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HOTTA Katsuyuki  堀田 勝幸

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… Alternative Names

堀田 勝幸  ホッタ カツユキ

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Researcher Number 70379816
Other IDs
Affiliation (Current) 2025: 岡山大学, 医療開発領域, 教授
Affiliation (based on the past Project Information) *help 2015 – 2023: 岡山大学, 大学病院, 教授
2014: 岡山大学, 大学病院, 講師
2013 – 2014: 岡山大学, 大学病院, 助教
2008: 岡山大, 助教
2007: Okayama University, 保健環境センター, 助教
2006: 岡山大学, 保健環境センター, 助手
Review Section/Research Field
Principal Investigator
Basic Section 50020:Tumor diagnostics and therapeutics-related / Tumor therapeutics / Public health/Health science
Except Principal Investigator
Basic Section 90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Respiratory organ internal medicine
Keywords
Principal Investigator
EGFR-TKI / 肺癌 / EGFR肺癌 / EGFR変異陽性肺癌 / EGFR遺伝子変異陽性肺癌 / インターロイキン6(IL-6) / EGFR遺伝子変異陽性非小細胞肺がん / チロシンキナーゼ阻害薬 / IL-6 / EGFR … More / クォンティフェロン検査 / 結核健診 / 医療系大学生 / ツベルクリン反応検査 / 結核検診 / クォンティフェロン … More
Except Principal Investigator
データマネジメント / 薬事承認申請 / 品質マネジメント / 先進医療 / 特定臨床研究 / 臨床研究法 / 悪性腫瘍 / 予防医学 / 遺伝子検査学 / 臨床検査システム / 固形癌 / メチル化 / エピゲノム / 先制医療 / 生体情報・計測 / 腫瘍検査学 / 検査・診断システム / mTOR阻害薬 / BIBW2552 / JAK1/2阻害薬 / everolimus / mTOR阻害薬 / 遺伝子改変マウス / 用量依存性 / gefitinib / AZD1480 / everolims / EGFR / NNK / Ogg1ホモノックアウトマウス / bevacizumab / cetuximab / JAK-1/2 inhibitors / everolimus (mTOR阻害薬), / afatinib / EGFR遺伝子改変マウス Less
  • Research Projects

    (6 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (20 People)
  •  EGFR肺癌における第3世代EGFR-TKI耐性へのIL-6の関与と克服の検討Principal Investigator

    • Principal Investigator
      堀田 勝幸
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Okayama University
  •  Quality management of Advanced medical care clinical resarch under Clinical Trial Act for pharmaceutial approval application

    • Principal Investigator
      Sakurai Jun
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90140:Medical technology assessment-related
    • Research Institution
      Okayama University
  •  Preemptive Medicine to Solid Tumors based on Epigenomics

    • Principal Investigator
      NAGASAKA TAKESHI
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90130:Medical systems-related
    • Research Institution
      Kawasaki Medical School
  •  Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutationsPrincipal Investigator

    • Principal Investigator
      Hotta Katsuyuki
    • Project Period (FY)
      2014 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Tumor therapeutics
    • Research Institution
      Okayama University
  •  Basic and clinical study of EGFR gene mutation-positive lung cancer using a genetically modified mouse

    • Principal Investigator
      KIURA Katsuyuki
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Okayama University
  •  医療系大学生に対するクォンティフェロン検査を用いた結核対策の精度向上に関する検討Principal Investigator

    • Principal Investigator
      堀田 勝幸
    • Project Period (FY)
      2006 – 2007
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Public health/Health science
    • Research Institution
      Okayama University

All 2018 2015 2014 2013 2012 2011 2007

All Journal Article Presentation

  • [Journal Article] Potential influence of interleukin-6 on the therapeutic effect of gefitinib in patients with advanced non-small cell lung cancer harbouring EGFR mutations.2018

    • Author(s)
      Tamura T, Kato Y, Ohashi K, Ninomiya K, Makimoto G, Gotoda H, Kubo T, Ichihara E, Tanaka T, Ichimura K, Maeda Y, Hotta K, Kiura K.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 495 Issue: 1 Pages: 360-367

    • DOI

      10.1016/j.bbrc.2017.10.175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K19454, KAKENHI-PROJECT-15H04830, KAKENHI-PROJECT-26430163, KAKENHI-PROJECT-16K15458
  • [Journal Article] Src mediates ERK reactivation in gefitinib resistance in non-small cell lung cancer.2014

    • Author(s)
      Ochi N, Takigawa N, Harada D, Yasugi M, Ichihara E, Hotta K, Tabata M, Tanimoto M, Kiura K.
    • Journal Title

      Exp Cell Res.

      Volume: 322 Issue: 1 Pages: 168-177

    • DOI

      10.1016/j.yexcr.2014.01.007

    • NAID

      120005517858

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
  • [Journal Article] A new human lung adenocarcinoma cell line harboring the EML4-ALK fusion gene.2014

    • Author(s)
      Isozaki H, Yasugi M, Takigawa N, Hotta K, Ichihara E, Taniguchi A, Toyooka S, Hashida S, Sendo T, Tanimoto M, Kiura K.
    • Journal Title

      Jpn J Clin Oncol

      Volume: 2014 Issue: 10 Pages: 963-968

    • DOI

      10.1093/jjco/hyu110

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Journal Article] Everolimus prolonged survival in transgenic mice with EGFR-driven lung tumors.2014

    • Author(s)
      Yasugi M, Takigawa N, Ochi N, Ohashi K, Harada D, Ninomiya T, Murakami T, Honda Y, Ichihara E, Tanimoto M, Kiura K.
    • Journal Title

      Exp Cell Res.

      Volume: 326 Issue: 2 Pages: 201-209

    • DOI

      10.1016/j.yexcr.2014.04.012

    • NAID

      120005526613

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-24591182, KAKENHI-PROJECT-25670399
  • [Journal Article] Vandetanib is effective in EGFR-mutant lung cancer cells with PTEN deficiency.2013

    • Author(s)
      Takeda H, Takigawa N, Ohashi K, Minami D, Kataoka I, Ichihara E, Ochi N, Tanimoto M, Kiura K.
    • Journal Title

      Mol Cancer Res

      Volume: 319 Issue: 2 Pages: 417-423

    • DOI

      10.1158/1541-7786.mcr-12-0401

    • NAID

      120005359097

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390221, KAKENHI-PROJECT-23651046, KAKENHI-PROJECT-24310042, KAKENHI-PLANNED-23114010
  • [Journal Article] Impact of physical size on gefitinib efficacy in patients with non-small cell lung cancer harboring EGFR mutations.2013

    • Author(s)
      Ichihara E, Hotta K, Takigawa N, Kudo K, Kato Y, Honda Y, Hayakawa H, Minami D, Sato A, Tabata M, Tanimoto M, Kiura K.
    • Journal Title

      Lung Cancer.

      Volume: 81 Issue: 3 Pages: 435-439

    • DOI

      10.1016/j.lungcan.2013.05.021

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Journal Article] Establishment of pemetrexed-resistant non-small cell lung cancer cell lines2011

    • Author(s)
      Zhang D, Ochi N, Takigawa N, Tanimoto I, Ichihara E, Hotta K, Tabata M, Tanimoto M, Kiura K
    • Journal Title

      Cancer Lett

      Volume: 309 Issue: 2 Pages: 228-235

    • DOI

      10.1016/j.canlet.2011.06.006

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Journal Article] Whole Blood Interferon-gamma Assay for Baseline Tuberculosis Screening among Japanese Healthcare Students2007

    • Author(s)
      Hotta K, et. al.
    • Journal Title

      Plos One 2(8)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18790397
  • [Presentation] Interleukin-6 Is a Valuable Predictive Marker for Therapeutic Effect of Gefitinib in Patients with Advanced NSCLC Harboring EGFR Mutations2015

    • Author(s)
      Y. Kato, K. Hotta, T. Tamura, T. Tanaka, K. Ichimura, K. Ohashi, T. Kubo, E. Ichihara, M. Tanimoto, K. Kiura
    • Organizer
      第16回世界肺癌会議
    • Place of Presentation
      米国コロラド州デンバー
    • Year and Date
      2015-09-06
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26430163
  • [Presentation] ALK inactivation induced acquired resistance to alectinib in lung cancer harboring EML4-ALK fusion gene.2014

    • Author(s)
      Hideko Isozaki, Eiki Ichihara, Masayuki Yasugi, Ocihi Nobuaki, Katsuyuki Hotta, Nagio Takigawa, Toshiaki Sendo, Mitsune Tanimoto, Katsuyuki Kiura
    • Organizer
      The 105th Annual Meeting of the American Association for Cancer Research
    • Place of Presentation
      San Diego, CA. USA
    • Year and Date
      2014-04-08
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Presentation] Afatinib prolonged survival in EGFR-driven lung cancer model compared to gefitinib2012

    • Author(s)
      Takashi Ninomiya, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura, Nagio Takigawa, Nobuaki Ochi, Masayuki Yasugi, Daijiro Harada.
    • Organizer
      AACR Annual Meeting 2012
    • Place of Presentation
      McCormick Place in Chicago, Illinois
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Presentation] Effect of AZD1480 on lung tumor in transgenic mice carrying activating EGFR mutation2012

    • Author(s)
      Toshi Murakami, Nagio Takigawa, Takashi Ninomiya, Nobuhiro Honda, Hideko Isozaki, Eiki Ichihara, Akiko Hisamoto, Katsuyuki Hotta, Mitsune Tanimoto, Katsuyuki Kiura
    • Organizer
      AACR Annual Meeting 2012
    • Place of Presentation
      McCormick Place in Chicago, Illinois
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Presentation] Role of ERK reactivation mediated by Src in acquired resistance to gefitinib in non-small cell lung cancer with EGFR mutation2011

    • Author(s)
      Ochi N, Takigawa N, Ohashi K, Takeda H, Fujii M, Kubo T, Ichihara E, Hotta K, Tanimoto M, Kiura K
    • Organizer
      AACR Annual Meeting 2011
    • Place of Presentation
      Orange County Convention Center, Orlando, FL, USA
    • Year and Date
      2011-04-03
    • Data Source
      KAKENHI-PROJECT-23390221
  • [Presentation] 医療系大学生に対するクォンティフェロン検査(QFT)を用いた結核対策の精度向2007

    • Author(s)
      堀田勝幸、他
    • Organizer
      第42回日本呼吸器学会中国四国地方会
    • Place of Presentation
      広島
    • Year and Date
      2007-07-06
    • Data Source
      KAKENHI-PROJECT-18790397
  • [Presentation] 医療系大学生に対するクォンティフェロン検査(QFT)を用いた結核対策の精度向2007

    • Author(s)
      堀田勝幸、他
    • Organizer
      第45回全国大学保健管理研究集会
    • Place of Presentation
      別府
    • Year and Date
      2007-10-11
    • Data Source
      KAKENHI-PROJECT-18790397
  • 1.  KIURA Katsuyuki (10243502)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 11 results
  • 2.  加藤 有加 (50544904)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  TKIGAWA Nagio (60325107)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 4.  TAKATA Minoru (30281728)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NAKABEPPU Yusaku (30180350)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  YOSHINO Tadashi (70183704)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  NAGASAKA TAKESHI (30452569)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  Sakurai Jun (30444657)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  市原 英基 (40549705)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 10 results
  • 10.  山口 佳之 (10230377)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  楳田 祐三 (10573735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  堅田 洋佑 (20716881)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  西田 直生志 (60281755)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  母里 淑子 (70708081)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  四方 賢一 (00243452)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  大野 彩 (20584626)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  Tamura Tomoki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 18.  Ninomiya Kiichiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  Ohashi Kadoaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 20.  Makimoto Go
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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