Ohno Mizuki 大野みずき

… Alternative Names

OHNO Mizuki 大野みずき

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Researcher Number	70380524
Other IDs
Affiliation (Current)	2025: 九州大学, 医学研究院, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 九州大学, 医学研究院, 助教 2016 – 2018: 九州大学, 医学研究院, 助教 2012 – 2016: 九州大学, 医学(系)研究科(研究院), 助教 2011 – 2012: 九州大学, 医学研究院, 助教 2009 – 2010: 九州大学, 大学院・医学研究院, 助教 2009: Kyushu University, 医学研究院, 助教
Review Section/Research Field	Principal Investigator Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related / Basic Section 45020:Evolutionary biology-related / Basic Section 45010:Genetics-related / Basic Section 44010:Cell biology-related / Risk sciences of radiation and chemicals / Evolutionary biology / Laboratory animal science / Genetics/Genome dynamics Except Principal Investigator Medium-sized Section 63:Environmental analyses and evaluation and related fields / Basic Section 55010:General surgery and pediatric surgery-related … More / Basic Section 59040:Nutrition science and health science-related / Basic Section 09080:Science education-related / Environmental and hygienic pharmacy / Health science and related fields / Environmental impact assessment / Risk sciences of radiation and chemicals / Biological Sciences Less
Keywords	Principal Investigator DNA修復 / ゲノム変異 / DNA損傷 / 生殖細胞 / 次世代影響 / 突然変異 / 生殖細胞ゲノム変異 / 継世代影響 / 酸化DNA損傷 / ゲノム維持機構 … More / 生殖細胞ゲノム / 遺伝情報維持 / 配偶子ゲノム / 卵子 / ゲノム維持 / 精子DNA損傷 / 卵子DNA修復 / 生物影響 / 環境ストレス / ミスマッチ修復 / 生殖細胞変異 / 非S期DNA合成 / 分子進化 / 遺伝子改変マウス / グノム変異 / エピミューテーション / 遺伝情報 … More Except Principal Investigator 酸化ストレス / 突然変異 / 遺伝学 / バイオインフォーマティクス / ミュータジェネシス / 発がん / ゲノム / 癌 / 遺伝子 / 低線量率放射線影響 / オミクス解析 / 進化多様性 / ゼブラフィッシュ / iPS細胞 / ヒルシュスプルング病類縁疾患 / 心臓 / 幹細胞 / 老化 / STEAM / 科学教育 / 遺伝リテラシー / 有害化学物質 / 環境 / 薬学 / 体内変異原性 / リスク評価 / 変異原物質 / ゲノム障害 / エクソーム解析 / 凍結保存 / 生殖細胞 / がんと遺伝 / MUTYH / OGG1 / MTH1 / ８-オキソグアニン / ミューテーターマウス / 体外受精 / 遺伝 / 生殖細胞突然変異 / 環境影響評価 / 次世代シーケンシング / マウスゲノム / 突然変異検出 / 進化 / 変異原性評価 / 実験動物 / 環境影響次世代評価 / ゲノム機能 / 生殖細胞系列突然変異 / ゲノム編集 / トランスクリプトーム / 集団遺伝学 / ゲノム機能解析 / ビッグデータ / トランスクリプトーム解析 / ゲノム解析 / 自然発生突然変異 / DNA修復 / DNA損傷 / 細胞死 / 消化管 / 活性酸素 / 動物 / 核酸 Less

卵子が持つ精子DNA損傷を修復する能力の分子機構解明と次世代ゲノム影響の解析Principal Investigator
- Principal Investigator
  
  大野みずき
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
  Basic Section 45020:Evolutionary biology-related
  Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related
- Research Institution
  Kyushu University
ヒルシュスプルング病類縁疾患モデルゼブラフィッシュを用いた新規治療法開発
- Principal Investigator
  
  近藤琢也
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55010:General surgery and pediatric surgery-related
- Research Institution
  Kyushu University
High-throughput and precision analysis of biological effects of low-dose-rate radiation.
- Principal Investigator
  
  権藤洋一
- Project Period (FY)
  2024 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 63:Environmental analyses and evaluation and related fields
- Research Institution
  Osaka University
初等教育における遺伝リテラシー向上のためのSTEAM教育プログラム開発の検討
- Principal Investigator
  
  鷹野典子 (甲斐典子)
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 09080:Science education-related
- Research Institution
  Kyushu University
心臓アンチエイジング薬の開発を目指したヒトiPS細胞由来老化心筋モデルの構築
- Principal Investigator
  
  日高京子
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  The University of Kitakyushu
Understanding molecular mechanism behind the oocyte's DNA repair ability of sperm genome damagePrincipal Investigator
- Principal Investigator
  
  Ohno Mizuki
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 44010:Cell biology-related
- Research Institution
  Kyushu University
An attempt to quantify and evaluate the effect of in vitro fertilization on the genomic information of offspring
- Principal Investigator
  
  SAKUMI KUNIHIKO
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Health science and related fields
- Research Institution
  Kyushu University
Characterization of mutation as a marker for carcinogenesis induced by oxidative stress: identification of mutation hotspot
- Principal Investigator
  
  AOKI Yasunobu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental and hygienic pharmacy
- Research Institution
  National Institute for Environmental Studies
Analysis of de novo germline mutations by using environmental genome stress-sensitive micePrincipal Investigator
- Principal Investigator
  
  Ohno Mizuki
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyushu University
Oxidative stress-induced mutagenesis and carcinogenesis in DNA repair-deficient mice
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyushu University
Detection of mouse germline mutations by ultra-throughput genomic analyses and development of the risk assessment system for low-dose mutagens
- Principal Investigator
  
  Gondo Yoichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Environmental impact assessment
- Research Institution
  Institute of Physical and Chemical Research
The role of non-S DNA synthesis on the local mutation ratePrincipal Investigator
- Principal Investigator
  
  OHNO Mizuki
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Evolutionary biology
- Research Institution
  Kyushu University
Study of molecular mechanisms of germline mutation by using DNA repair deficient micePrincipal Investigator
- Principal Investigator
  
  OHNO Mixuki
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Kyushu University
DNA修復欠損マウスを用いたエピミューテーションの解析Principal Investigator
- Principal Investigator
  
  大野みずき
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Genetics/Genome dynamics
- Research Institution
  Kyushu University
Oxidative stress-induced tumorigenesis in the small intestines of various types of DNA repair-deficient mice
- Principal Investigator
  
  TSUZUKI Teruhisa
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University

[Book] 日本臨牀（増刊号）最新臨床大腸癌学基礎研究から臨床応用へ2015
- Author(s)
  續輝久、大野みずき、中津可道
- Total Pages
  715
- Publisher
  株式会社日本臨牀社
- Data Source
  KAKENHI-PROJECT-25241012
[Book] 疾患モデルマウス表現型解析指南/DNA修復2011
- Author(s)
  大野みずき, 績輝久
- Publisher
  中山書店
- Data Source
  KAKENHI-PROJECT-22300144
[Journal Article] Oxidative stress accelerates intestinal tumorigenesis by enhancing 8-oxoguanine-mediated mutagenesis in MUTYH-deficient mice2024
- Author(s)
  Ohno, M., N. Takano, K. Hidaka, F. Sasaki, K. Yamauchi, Y. Aoki, T. Nohmi, Y. Nakabeppu, Y. Nakatsu, T. Tsuzuki
- Journal Title
  
  Genome Research
  
  Volume: 34 Issue: 1 Pages: 47-56
- DOI
  10.1101/gr.278326.123
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K02963, KAKENHI-PROJECT-22K11733, KAKENHI-PROJECT-20H03254
[Journal Article] Endogenous ROS production in early differentiation state suppresses endoderm differentiation via transient FOXC1 expression2022
- Author(s)
  Oka Sugako、Tsuzuki Teruhisa、Hidaka Masumi、Ohno Mizuki、Nakatsu Yoshimichi、Sekiguchi Mutsuo
- Journal Title
  
  Cell Death Discovery
  
  Volume: 8 Issue: 1 Pages: 150-150
- DOI
  10.1038/s41420-022-00961-2
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K09915, KAKENHI-PROJECT-22K11733, KAKENHI-PROJECT-20H03254
[Journal Article] Characteristic mutations induced in the small intestine of Msh2-knockout gpt delta mice2021
- Author(s)
  Aoki Yasunobu、Ohno Mizuki、Matsumoto Michiyo、Matsumoto Michi、Masumura Kenichi、Nohmi Takehiko、Tsuzuki Teruhisa
- Journal Title
  
  Genes and Environment
  
  Volume: 43 Issue: 1 Pages: 27-27
- DOI
  10.1186/s41021-021-00196-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03254, KAKENHI-PROJECT-19K12347
[Journal Article] Oxidative-stress-driven in vivo mutagenesis induced by oral administration of potassium bromate in the small intestines of gpt delta mice2020
- Author(s)
  Aoki Y, Taniguchi Y, Matsumoto M, Matsumoto M, Ohno M, Masumura K, Sasaki S, Tsuzuki T, Yamamoto M, Nohmi T
- Journal Title
  
  Mutation Reseaｒch
  
  Volume: 850-851 Pages: 503136-503136
- DOI
  10.1016/j.mrgentox.2020.503136
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K12347, KAKENHI-PROJECT-17K19494, KAKENHI-PROJECT-20H03254
[Journal Article] Spontaneous <i>de novo</i> germline mutations in humans and mice: rates, spectra, causes and consequences2019
- Author(s)
  Ohno, M.
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 94 Issue: 1 Pages: 13-22
- DOI
  10.1266/ggs.18-00015
- NAID
  130007625024
- ISSN
  1341-7568, 1880-5779
- Year and Date
  2019-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H05109, KAKENHI-PROJECT-17K19913
[Journal Article] Toward understanding <i>de novo</i> germline mutations in mammals2019
- Author(s)
  Ohno Mizuki
- Journal Title
  
  Genes Genet. Syst.
  
  Volume: 94 Issue: 1 Pages: 1-1
- DOI
  10.1266/ggs.94.1
- NAID
  130007625087
- ISSN
  1341-7568, 1880-5779
- Year and Date
  2019-02-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19913
[Journal Article] Analysis of de novo germline genome mutations2018
- Author(s)
  Ohno, M.
- Journal Title
  
  Impact
  
  Volume: 2018 Issue: 3 Pages: 63-65
- DOI
  10.21820/23987073.2018.3.63
- Open Access
- Data Source
  KAKENHI-PROJECT-16H05109, KAKENHI-PROJECT-17K19913
[Journal Article] PSMC5, a 19S Proteasomal ATPase, Regulates Cocaine Action in the Nucleus Accumbens.2015
- Author(s)
  Ohnishi YH, Ohnishi YN, Nakamura T, Ohno M, Kennedy PJ, Yasuyuki O, Nishi A, Neve R, Tsuzuki T, Nestler EJ.
- Journal Title
  
  PLoS One
  
  Volume: 10(5) Issue: 5 Pages: e0126710-e0126710
- DOI
  10.1371/journal.pone.0126710
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591735, KAKENHI-PLANNED-24108009, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-26281022, KAKENHI-PROJECT-26290064
[Journal Article] Germline mutation rates and the long-term phenotypic effects of mutation accumulation in wild-type laboratory mice and mutator mice2015
- Author(s)
  Arikuni Uchimura, Mayumi Higuchi, Yohei Minakuchi, Mizuki Ohno, Atsushi Toyoda, Asao Fujiyama, Ikuo Miura, Shigeharu Wakana, Jo Nishino, Takeshi Yagi
- Journal Title
  
  Genome Research
  
  Volume: 25 Issue: 8 Pages: 1125-1134
- DOI
  10.1101/gr.186148.114
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K12205, KAKENHI-PROJECT-15K14368, KAKENHI-PROJECT-221S0002, KAKENHI-PROJECT-26281022
[Journal Article] Mismatch repair deficient mice show susceptibility to oxidative stress-induced intestinal carcinogenesis2014
- Author(s)
  J. Piao, Y. Nakatsu, M. Ohno, K. Taguchi, T. Tsuzuki
- Journal Title
  
  International Journal of Biological Sciences
  
  Volume: 10 Issue: 1 Pages: 73-79
- DOI
  10.7150/ijbs.5750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-24108001, KAKENHI-PLANNED-24108009, KAKENHI-PROJECT-25241012, KAKENHI-PROJECT-26340025
[Journal Article] 8-oxoguanine causes spontaneous de novo germline mutations in mice.2014
- Author(s)
  Ohno, M., Sakumi, K., Fukumura, R., Furuichi, M., Iwasaki, Y., Hokama, M., Ikemura, T., Tsuzuki, T., and Nakabeppu, Y.
- Journal Title
  
  Sci Rep
  
  Volume: 4 Issue: 1 Pages: 4689-4689
- DOI
  10.1038/srep04689
- NAID
  120005703609
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22221004, KAKENHI-PLANNED-24108009, KAKENHI-PROJECT-25241012, KAKENHI-PROJECT-25241016
[Journal Article] 酸化損傷塩基がほ乳類ゲノムに及ぼす影響2010
- Author(s)
  大野みずき
- Journal Title
  
  福岡医学雑誌
  
  Volume: 101 Pages: 61-68
- Data Source
  KAKENHI-PROJECT-21657002
[Journal Article] NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals2010
- Author(s)
  Abolhassani, N, Iyama, T, Tsuchimoto, D, Sakumi, K, Ohno, M, Behmanesh, M, Nakabeppu, Y.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 9 Pages: 2891-2903
- NAID
  120005227421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22300144
[Journal Article] NUDT16 and ITPA play a dual protective role in maintaining chromosome stability and cell growth by eliminating dIDP/IDP and dITP/ITP from nucleotide pools in mammals2010
- Author(s)
  Abolhassani, N, lyama, T, Tsuchimoto, D, Sakumi, K, Ohno, M, Behmanesh, M, Nakabeppu, Y.
- Journal Title
  
  Nucleic Acids Research
  
  Volume: 9 Pages: 2891-2903
- NAID
  120005227421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21657002
[Journal Article] 酸化損傷塩基がほ乳類ゲノムに及ぼす影響2010
- Author(s)
  大野みずき
- Journal Title
  
  福岡医学雑誌
- Data Source
  KAKENHI-PROJECT-22300144
[Journal Article] Quantitative analysis of oxidized guanine, 8-oxoguanine, in mitochondrial DNA by immunofluorescence method2009
- Author(s)
  Ohno M, et al.
- Journal Title
  
  Methods Mol Biol. 554
  
  Pages: 199-212
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] De novo germline mutation rate and spectra in DNA repair-deficient mice lines2023
- Author(s)
  Mizuki Ohno, Noriko Takano, Kyoko Hidaka, Teruhisa Tsuzuki
- Organizer
  XXIIIrd International Congress of Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] 内在性酸化ストレス制御ヒトiPS細胞を用いた心筋細胞老化モデルの樹立2023
- Author(s)
  岡素雅子，李俊，王苑犁，鷹野典子，大野みずき，李鍾國，日高京子
- Organizer
  第46回日本生物学会年会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] Causes and mechanisms of de novo germline mutations2023
- Author(s)
  Mizuki Ohno
- Organizer
  Biological Effects & Application of Radiation 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] The biological response to internal and external exposure to cesium-137 may be different even at equivalent doses2023
- Author(s)
  Hiroo Nakajima, Mizuki Ohno, Noriko Takano, Satoru Endo, Hiroshi Ishihara
- Organizer
  International Commission on Radiological Protection (ICRP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Analysis of oxidative stress-induced somatic mutations in DNA mismatch repair-deficient mice2023
- Author(s)
  Noriko Takano, Kyoko Hidaka, Fumiko Sasaki, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Mizuki Ohno
- Organizer
  XXIIIrd International Congress of Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] rpsL-Tg/Msh2欠損マウスを用いた体細胞突然変異解析：NGS解析との比較2023
- Author(s)
  鷹野典子、日高京子、青木康展、能美健彦、中津可道、續輝久、大野みずき
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Establishment of a human iPS cell-derived senescent cardiomyocyte model by regulating endogenous ROS production2023
- Author(s)
  Sugako Oka, Li Jun, Wang Yuanli, Noriko Takano, Mizuki Ohno, Lee Jong-Kook, Kyoko Hidaka
- Organizer
  日本分子生物学会大46回
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Establishment of a human iPS cell-derived senescent cardiomyocyte model by regulating endogenous ROS production2023
- Author(s)
  Sugako Oka, Li Jun, Wang Yuanli, Noriko Takano, Mizuki Ohno, Lee Jong-Kook, Kyoko Hidaka
- Organizer
  日本分子生物学会大46回
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] A multidisciplinary challenge to assess the next-generation risks of low-dose-rate long-term gamma-ray exposure by whole-genome sequencing in the mouse model2023
- Author(s)
  Yoichi Gondo, Arikuni Uchimura, Manabu Yoneya, Satoshi Tanaka, Jun-Ichiro Komura, Minoru Kimura, Mizuki Ohno, Hiroshi Toki, Masako Bando, Yuichi Tsunoyama, Yoshihisa Matsumoto, Hisaji Maki, Yoshiya Shimada
- Organizer
  International Commission on Radiological Protection Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] マウスを用いた生殖細胞変異の研究2023
- Author(s)
  大野みずき
- Organizer
  日本環境変異原ゲノム学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 生殖細胞ゲノム変異の頻度とスペクトルに影響するDNA修復因子2023
- Author(s)
  大野みずき、鷹野典子、日髙京子
- Organizer
  日本遺伝学会第95回
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] DNA 修復欠損マウスを利用した心臓老化関連変異の探索2023
- Author(s)
  日高京子，岡寿雅子，鷹野典子，李鍾國，大野みずき
- Organizer
  日本環境変原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] 酸化ストレスはDNAミスマッチ修復機構欠損マウスのゲノム中のShort Tandem Repeat (STR) 配列での変異を増加させる2023
- Author(s)
  鷹野典子，日高京子，佐々木史子，中津可道，續輝久，大野みずき
- Organizer
  第46回日本生物学会年会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] rpsL-Tg/Msh2欠損マウスを用いた体細胞突然変異解析：NGS解析との比較2023
- Author(s)
  鷹野典子、日高京子、青木康展、能美健彦、中津可道、續輝久、大野みずき
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Oxidative stress increases Short Tandem Repeat (STR) instability in DNA mismatch repair-deficient mice genome2023
- Author(s)
  鷹野典子、日高京子、佐々木史子、中津可道、續輝久、大野みずき
- Organizer
  日本分子生物学会大46回
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 生殖細胞ゲノム変異の頻度とスペクトルに影響するDNA修復因子2023
- Author(s)
  大野みずき、鷹野典子、日髙京子
- Organizer
  日本遺伝学会第95回
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Exploring Cardiac Aging-Associated Mutations Using DNA Repair-Deficient Mice2023
- Author(s)
  Kyoko HIDAKA, Sugako OKA, Noriko TAKANO, Jong-Kook LEE, Mizuki OHNO
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] DNAミスマッチ修復欠損マウスの消化管における体細胞突然変異および酸化ストレス誘発体細胞突然変異の解析2023
- Author(s)
  鷹野典子，日高京子，佐々木史子，中津可道，續輝久，大野みずき
- Organizer
  日本遺伝学会第95回
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Impact of sperm DNA damage and oocyte-DNA repair ability on mouse reproduction2023
- Author(s)
  佐々木史子、鷹野典子、日高京子、大野みずき
- Organizer
  日本分子生物学会大46回
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Analysis of oxidative stress-induced somatic mutations in DNA mismatch repair-deficient mice2023
- Author(s)
  Noriko Takano, Kyoko Hidaka, Fumiko Sasaki, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Mizuki Ohno
- Organizer
  XXIIIrd International Congress of Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Oxidative stress increases Short Tandem Repeat (STR) instability in DNA mismatch repair-deficient mice genome2023
- Author(s)
  鷹野典子、日高京子、佐々木史子、中津可道、續輝久、大野みずき
- Organizer
  日本分子生物学会大46回
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] 精子DNA損傷と卵子のDNA修復機構2023
- Author(s)
  大野みずき
- Organizer
  日本臨床エンブリオロジスト学会第29回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 家族性大腸がんモデルマウスを用いた腫瘍発生数の線量率応答解析2023
- Author(s)
  藤通有希、星裕子、大野みずき、冨田雅典
- Organizer
  放射線影響学会第66回大会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] rpsL-Tg/Msh2 欠損マウスを用いた体細胞突然変異解析：NGS 解析との比較2023
- Author(s)
  鷹野典子，日高京子，青木康展，能美健彦，中津可道，續輝久，大野みずき
- Organizer
  日本環境変原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] DNAミスマッチ修復欠損マウスの消化管における体細胞突然変異および酸化ストレス誘発体細胞突然変異の解析2023
- Author(s)
  鷹野典子，日高京子，佐々木史子，中津可道，續輝久，大野みずき
- Organizer
  日本遺伝学会第95回
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Effect of Cs-137 internal exposure on mutagenesis and tumorigenesis in mice intestines2023
- Author(s)
  Mizuki Ohno, Hiroshi Ishihara, Hiroo Nakajima
- Organizer
  放射線影響学会第66回大会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] The biological response to internal and external exposure to cesium-137 may be different even at equivalent doses2023
- Author(s)
  Hiroo Nakajima, Mizuki Ohno, Noriko Takano, Satoru Endo, Hiroshi Ishihara
- Organizer
  International Commission on Radiological Protection (ICRP)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] De novo germline mutation rate and spectra in DNA repair-deficient mice lines2023
- Author(s)
  Mizuki Ohno, Noriko Takano, Kyoko Hidaka, Teruhisa Tsuzuki
- Organizer
  XXIIIrd International Congress of Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Exploring Cardiac Aging-Associated Mutations Using　DNA Repair-Deficient Mice2023
- Author(s)
  Kyoko HIDAKA, Sugako OKA, Noriko TAKANO, Jong-Kook LEE, Mizuki OHNO
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] High-precision detection of de novo mutations and application to risk assessment for the low-dose-rate longtime exposure to radiation2023
- Author(s)
  Yoichi Gondo, Arikuni Uchimura, Manabu Yoneya, Satoshi Tanaka, Jun-Ichiro Komura, Minoru Kimura, Mizuki Ohno, Hiroshi Toki, Masako Bando, Yuichi Tsunoyama, Yoshihisa Matsumoto, Hisaji Maki, Yoshiya Shimada
- Organizer
  第14回国際ゲノム会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Impact of sperm DNA damage and oocyte-DNA repair ability on mouse reproduction2023
- Author(s)
  佐々木史子、鷹野典子、日高京子、大野みずき
- Organizer
  日本分子生物学会大46回
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Toward a new risk assessment system for low-dose/low-dose-rate long exposure to radiation2023
- Author(s)
  Yoichi Gondo, Arikuni Uchimura, Manabu Yoneya, Satoshi Tanaka, Jun-Ichiro Komura, Minoru Kimura, Mizuki Ohno, Hiroshi Toki, Masako Bando, Yuichi Tsunoyama, Yoshihisa Matsumoto, Hisaji Maki, Yoshiya Shimada
- Organizer
  Biological Effects & Application of Radiation 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Oxidative Stress-Induced Mutagenesis and Tumorigenesis in MUTYH-Deficient Mice2023
- Author(s)
  Noriko Takano, Kyoko Hidaka, Fumiko Sasaki, Kazumi Yamauchi, Yasunobu Aoki, Takehiko Nohmi, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuki, Mizuki Ohno
- Organizer
  Biological Effects & Application of Radiation 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 137Cs の低線量内部被曝による抗腫瘍性免疫サイトカインの増加2022
- Author(s)
  中島裕夫、大野みずき、石原弘、宇野賀津子
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 酸化ストレスがDNAミスマッチ修復欠損マウスのゲノムにおよぼす影響2022
- Author(s)
  鷹野典子，日高京子，佐々木史子，中津可道，續輝久，大野みずき
- Organizer
  第45回日本生物学会年会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] 内在性酸化 DNA 損傷が生殖細胞ゲノムに及ぼす影響の解析:DNA 修復欠損マウスの研究から2022
- Author(s)
  大野みずき，鷹野典子，佐々木史子，日高京子
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] Expanded complete outbreeding method for the risk assessment of low-dose-rate long-exposure to gamma-ray in the mouse model2022
- Author(s)
  Yoichi Gondo, Satoshi Tanaka, Jun-Ichiro Komura, Minoru Kimura, Mizuki Ohno, Yoshihisa Matsumoto, Hisaji Maki
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] de novo 生殖細胞変異検出のためのパイプライン - 酸化 DNA 損傷修復欠損マウスを用いて2022
- Author(s)
  日高京子，鷹野典子，佐々木史子，大野みずき
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] DNAミスマッチ修復欠損マウスを用いた酸化ストレス誘発体細胞突然変異の解析2022
- Author(s)
  鷹野典子，日高京子，佐々木史子，中津可道，續輝久，大野みずき
- Organizer
  日本遺伝学会第94回大会
- Data Source
  KAKENHI-PROJECT-22K11733
[Presentation] DNAミスマッチ修復欠損マウスを用いた酸化ストレス誘発体細胞突然変異の解析2022
- Author(s)
  鷹野典子、日高京子、佐々木史子、中津可道、續輝久、大野みずき
- Organizer
  第94回日本遺伝学会
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Analysis of De novo Germline Mutations in DNA Repair Deficient Mice Lines2022
- Author(s)
  Mizuki Ohno
- Organizer
  13th International Conference on Environmental Mutagens
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 6 Impact of endogenous oxidative DNA damage on germline mutations: study from repair-deficient mice2022
- Author(s)
  Mizuki OHNO, Noriko TAKANO, Fumiko SASAKI, Kyoko HIDAKA
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 酸化ストレスがDNAミスマッチ修復欠損マウスのゲノムにおよぼす影響2022
- Author(s)
  鷹野典子、日高京子、佐々木史子、中津可道、續輝久、大野みずき
- Organizer
  第45回日本分子生物学会
- Data Source
  KAKENHI-PROJECT-22K02963
[Presentation] Analysis of De novo Germline Mutations in DNA Repair Deficient Mice Lines2022
- Author(s)
  Mizuki Ohno
- Organizer
  13th International Conference on Environmental Mutagens (ICEM2022)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 分化初期の酸化ストレスが細胞運命を変えるメカニズム2022
- Author(s)
  岡素雅子、續輝久、日高真純、大野みずき、中津可道、関口睦夫
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Impact of sperm DNA damage and oocyte DNA repair ability on mouse reproduction2022
- Author(s)
  Fumiko Sasaki, Kyoko Hidaka, Noriko Takano, Mizuki Ohno
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 生殖細胞変異検出のためのパイプライン - 酸化DNA損傷修復欠損マウスを用いて2022
- Author(s)
  日高京子、鷹野典子、佐々木史子、大野みずき
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] Effect of Cs-137 internal exposure on mutagenesis and tumorigenesis in mice intestines2022
- Author(s)
  Mizuki Ohno, Hiroshi Ishihara, Hiroo Nakajima
- Organizer
  日本放射線影響学会第65回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 7 Simultaneous sensitive quantification methodology of γH2ax-positive cells and DNA damage-induced RNAs induced by low-dose radiation in white blood cells of mouse2022
- Author(s)
  田中泉、石原弘、中島裕夫、大野みずき、田中美香、横地和子、上原章寛、武田志乃
- Organizer
  日本放射線影響学会第65回大会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] psLトランスジェニックマウスを用いたセシウム137の慢性的内部被ばくによる体細胞突然変異の解析2021
- Author(s)
  大野みずき, 鷹野典子, 中島裕夫, 石原弘, 中津可道, 續輝久
- Organizer
  日本環境異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] マウスにおけるセシウム137の低線量内部被ばくによる抗腫瘍免疫反応2021
- Author(s)
  中島裕夫, 宇野賀津子, 大野みずき, 石原弘, 續輝久, 米倉義晴
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] de novo Germline Mutation の頻度とスペクトルに影響する因子2021
- Author(s)
  大野みずき、鷹野典子、日高京子
- Organizer
  日本遺伝学会第93回大会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 暗期におけるアルキル化剤による小核誘発の増加はミスマッチ修復機構が関与する2021
- Author(s)
  伊藤圭一, 益森勝志, 大野みずき, 續輝久, 下位香代子
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] rpsLトランスジェニックマウスを用いたセシウム137の慢性的内部被ばくによる体細胞突然変異の解析2021
- Author(s)
  大野みずき, 鷹野典子, 中島裕夫, 石原弘, 中津可道, 續輝久
- Organizer
  日本環境変異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] ミスマッチ修復欠損条件下でgpt deltaマウス小腸に誘発される特徴的突然変異2021
- Author(s)
  青木康展, 大野みずき, 松本みちよ, 松本理, 増村健一, 能美健彦, 續輝久
- Organizer
  日本環境異原ゲノム学会
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] 生殖細胞での突然変異率と変異スペクトルに影響する因子は何か？2020
- Author(s)
  大野みずき
- Organizer
  日本遺伝学会
- Invited
- Data Source
  KAKENHI-PROJECT-20H03254
[Presentation] The impact of DNA repair status on germline mutation rate and spectra in mice2018
- Author(s)
  Ohno, M, Takano, N. Sakumi, K. Tsuzuki, T.
- Organizer
  SMBE2018 (Society for Molecular Biology and Evolution)
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 多世代にわたり低線量137Cs 内部被曝したA / J およびB6 マウスにおける全ゲノム解析2018
- Author(s)
  中島裕夫, 大野みずき、石原弘, 鈴木正敏, 遠藤曉, 遠藤大二, 續輝久, 藤堂剛
- Organizer
  日本環境変異原学会第47回大会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Application of transgenic mice to analyze genotoxic effects induced by non-thermal atmospheric air plasma2018
- Author(s)
  Yoshimichi Nakatsu, Noriko Takano, Mizuki Ohno, Satoshi Kitazaki, Kazunori Koga, Akiyo Tanaka, Masaharu Shiratani
- Organizer
  10th Anniversary International Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials/11th International Conference on Plasma-Nano Technology & Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] 生殖細胞ゲノム変異の発生原因と遺伝情報維持を担う分子機構2018
- Author(s)
  大野みずき、鷹野典子、作見邦彦
- Organizer
  第44回日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] Application of transgenic mice to analyze genotoxic effects induced by non-thermal atmospheric air plasma2018
- Author(s)
  Nakatsu, Y. Takano, N. Ohno, M. Kitazaki, S. Koga, K. Tanaka, A. Shiratani, M.
- Organizer
  10th Anniversary International Symposium on Advanced Plasma Science and its Applications for Nitrides and Nanomaterials/11th International Conference on Plasma-Nano Technology & Science
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 多世代にわたり低線量137Cs 内部被曝したA / J およびB6 マウスにおける全ゲノム解析2018
- Author(s)
  中島裕夫, 大野みずき、石原弘, 鈴木正敏, 遠藤曉, 遠藤大二, 續輝久, 藤堂剛
- Organizer
  日本環境変異原学会第47回大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] The impact of DNA repair status on germline mutation rate and spectra in mice2018
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Teruhisa Tsuzuki
- Organizer
  SMBE2018 (Society for Molecular Biology and Evolution)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] 生殖細胞ゲノム変異の発生原因と遺伝情報維持を担う分子機: Causes of de novo germline mutation and molecular mechanisms of genome integrity2018
- Author(s)
  大野みずき, 鷹野典子, 作見邦彦
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 学内の日本人学生の放射線に対する意識の変遷と外国人の放射線業務従事者の放射線についての知識の現状2018
- Author(s)
  中島　裕美子、安富祖　仁、佐藤　直紀、藤淵　俊王、野邉　由紀子、大野　みずき、平田　悠真、山里　眞、續　輝久、玉城　史朗
- Organizer
  日本放射線影響学会第６1回大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] ミスマッチ修復欠損マウスにおける体細胞および生殖細胞自然突然変異の解析2018
- Author(s)
  大野みずき, 鷹野典子, 中津可道, 續輝久
- Organizer
  日本放射線影響学会第６1回大会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Oxidative stress-induced tumorigenesis: Lesson from the experiments with DNA repair-deficient mice2018
- Author(s)
  Tsuzuki, T., Ohno, M., Takano, N., Taguchi, K., Nakatsu, Y
- Organizer
  Beijing Symposium on “Genomic Stability and Accurate Gene Expression under Oxidative Stress”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] ミスマッチ修復欠損マウスにおける体細胞および生殖細胞自然突然変異の解析2018
- Author(s)
  大野　みずき、鷹野　典子、中津　可道、續　輝久
- Organizer
  日本放射線影響学会第６1回大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] 学内の日本人学生の放射線に対する意識の変遷と外国人の放射線業務従事者の放射線についての知識の現状2018
- Author(s)
  中島裕美子、安富祖仁、佐藤直紀、藤淵俊王、野邉由紀子、大野みずき、平田悠真、山里眞、續輝久、玉城史朗
- Organizer
  日本放射線影響学会第６1回大会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Oxidative DNA damage and Repair in Cancer and Aging.2018
- Author(s)
  Yusaku Nakabeppu, Nona Abolhassani, Eiko Ohta, Zijing Sheng, Mizuki Ohno, Daisuke Tsuchimoto, Kunihiko Sakumi
- Organizer
  The 14th Japan - Korea Joint Symposium on Cancer and Ageing Research
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] 高感度変異検出をめざした多能性幹細胞におけるミューテーター株の作製2018
- Author(s)
  日高京子、林田元気、日高真純、大野みずき、續輝久、中津可道
- Organizer
  第41回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] DNA repair system as a constituent of mechanism underlying practical threshold of oxidative stress-induced tumorigenesis2017
- Author(s)
  Tsuzuki, T., Ohno, M., Takano, N., Taguchi, K., Nakabeppu, Y., Nakatsu, Y.
- Organizer
  2017年度生命科学系学会合同年次大会［日本分子生物学会第40回年会／日本生化学会第90回大会］
- Invited
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 遺伝性大腸がんモデルマウスにおける酸化ストレス誘発発がんと体細胞突然変異の解析2017
- Author(s)
  大野みずき、鷹野典子、中津可道、佐々木史子、作見邦彦、中別府雄作、續輝久
- Organizer
  日本放射線影響学会第60回大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 遺伝性大腸がんモデルマウスにおける酸化ストレス誘発発がんと体細胞突然変異の解析2017
- Author(s)
  大野みずき, 鷹野典子, 佐々木史子, 作見邦彦, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本放射線影響学会第60回大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] DNA repair system as a constituent of mechanism underlying practical threshold of oxidative stress-induced tumorigenesis2017
- Author(s)
  Tsuzuki, T., Ohno, M., Takano, N., Taguchi, K., Nakabeppu, Y., Nakatsu, Y.
- Organizer
  The 12th International Conference and the 5th Asian Congress on Environmental Mutagens
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 大腸癌モデルマウスを用いた酸化ストレス誘発発がんと体細胞突然変異の解析2017
- Author(s)
  大野みずき、鷹野典子、日高京子、作見邦彦、中別府雄作、中津可道、續輝久
- Organizer
  日本癌学会第76回学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Oxidative stress-induced intestinal tumors in Mutyh-deficient mice treated with low doses of potassium bromate2017
- Author(s)
  Tsuzuki, T., Ohno, M., Takano, N., Taguchi, K., Nakabeppu, Y., Aoki, Y., Nohmi, T., Nakatsu, Y.
- Organizer
  6th US-Japan DNA Repair Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Oxidative stress-induced mutagenesis in Msh2-deficient mice2017
- Author(s)
  Takano, N., Ohno, M., Hidaka, K., Nakatsu, Y., Tsuzuki, T.
- Organizer
  日本癌学会第76回学術総会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 遺伝性疾患自然発症モデル動物としてのmutator mouse2017
- Author(s)
  作見邦彦, 大野みずき, 中別府雄作
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] Somatic mutation analysis of oxodative stress-induced colon cancer model2017
- Author(s)
  大野みずき, 鷹野典子, 高野京子, 作見邦彦, 中別府雄作, 中津可道, 續輝久
- Organizer
  第76回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K19913
[Presentation] セシウム137の低線量内部被ばくによる生物影響：Msh2欠損マウスを用いた体細胞突然変異解析の試み2017
- Author(s)
  大野みずき、鷹野典子、中津可道、石原弘、中島裕夫、續輝久
- Organizer
  日本環境変異原学会第46回大会
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Oxidative stress-induced tumorigenesis: Lesson from the experiments with DNA repair-deficient mice2017
- Author(s)
  Tsuzuki, T., Ohno, M., Takano, N., Taguchi, K., Nakabeppu, Y., Nakatsu, Y.
- Organizer
  4th Transgenic Technology Meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] ミスマッチ修復欠損マウスを用いた新規生殖細胞変異の検出2016
- Author(s)
  大野みずき、鷹野典子、佐々木史子、中津可道、續輝久
- Organizer
  日本環境変異原学会第45回大会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Regulation of base substitution mutagenesis and chromosome recombination induced by 8-oxoguanine accumulated in the genome2016
- Author(s)
  大野みずき、作見邦彦、中別府雄作
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-12-03
- Invited
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Mutyh欠損マウスにおける酸化ストレスによる消化管腫瘍発生頻度上昇と特異的体細胞変異シグニチャーの解析2016
- Author(s)
  鷹野典子、大野みずき、中津可道、中別府雄作、續輝久
- Organizer
  日本分子生物学会第39回年会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] ミスマッチDNA修復系が体細胞および生殖細胞ゲノムにおよぼす影響2016
- Author(s)
  鷹野典子, 大野みずき, 佐々木史子, 中津可道, 續輝久
- Organizer
  日本遺伝学会
- Place of Presentation
  三島
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Mutyh欠損マウスにおける酸化ストレスによる消化管腫瘍発生頻度上昇と特異的体細胞変異シグニチャーの解析2016
- Author(s)
  鷹野典子、大野みずき、中津可道、中別府雄作、續輝久
- Organizer
  日本分子生物学会第39回年会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-12-02
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] ミスマッチ修復欠損マウスを用いた新規生殖細胞変異の検出2016
- Author(s)
  大野みずき、鷹野典子、佐々木史子、中津可道、續輝久
- Organizer
  日本環境変異原学会第45回大会
- Place of Presentation
  つくば国際会議場（茨城）
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 体細胞と生殖細胞のゲノム維持における酸化損傷DNAの修復機構の重要性2016
- Author(s)
  大野みずき
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  三島
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 酸化ストレスによる消化管腫瘍発生頻度上昇と特異的体細胞変異シグニチャー： Mutyh欠損マウスを用いた解析2016
- Author(s)
  大野みずき、鷹野典子、中津可道、中別府雄作、續輝久
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] ミスマッチ修復欠損マウスを用いた新規生殖細胞変異の検出2016
- Author(s)
  大野みずき, 鷹野典子, 佐々木史子, 中津可道, 續輝久
- Organizer
  日本環境変異原学会
- Place of Presentation
  つくば
- Year and Date
  2016-11-17
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] ミスマッチDNA修復系が体細胞および生殖細胞ゲノムにおよぼす影響2016
- Author(s)
  鷹野典子、大野みずき、佐々木史子、中津可道、續輝久
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  日本大学国際関係学部（静岡）
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] 酸化ストレスによる消化管腫瘍発生頻度上昇と特異的体細胞変異シグニチャー： Mutyh欠損マウスを用いた解析2016
- Author(s)
  大野みずき、鷹野典子、中津可道、中別府雄作、續輝久
- Organizer
  第75回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜（神奈川）
- Year and Date
  2016-10-07
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] ミスマッチDNA修復系が体細胞および生殖細胞ゲノムにおよぼす影響2016
- Author(s)
  鷹野典子、大野みずき、佐々木史子、中津可道、續輝久
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  三島
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 体細胞と生殖細胞のゲノム維持における酸化損傷DNAの修復機構の重要性2016
- Author(s)
  大野みずき
- Organizer
  日本遺伝学会
- Place of Presentation
  三島
- Year and Date
  2016-09-07
- Invited
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] 体細胞と生殖細胞のゲノム維持における酸化損傷DNAの修復機構の重要性2016
- Author(s)
  大野みずき
- Organizer
  日本遺伝学会第88回大会
- Place of Presentation
  日本大学国際関係学部（静岡）
- Year and Date
  2016-09-06
- Invited
- Data Source
  KAKENHI-PROJECT-16H05109
[Presentation] Maintenance of genome integrity: rate, causes and consequences of de novo germline mutation2016
- Author(s)
  Mizuki Ohno
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Invited
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Oxidative Stress-induced Tumorigenesis: Lesson from the Experiments with DNA Repair-deficient Mice2015
- Author(s)
  Teruhisa Tsuzuki, Mizuki Ohno, Noriko Takano, Kenichi Taguchi, Yusaku Nakabeppu, Yoshimichi Nakatsu
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto（京都国際会議場）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Mth1, Ogg1, Mutyh 三重欠損マウス家系を用いた生殖細胞突然変異の解析2015
- Author(s)
  作見邦彦, 大野みずき, 権藤洋一, 續輝久, 中別府雄作
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Influence of oxidative DNA damage on the rate of somatic and germline mutation2015
- Author(s)
  Ohno Mizuki, Takano Noriko, SAKUMI Kunihiko, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Analysis of oxidative stress-induced intestinal tumors in Trp53-deficient mice2015
- Author(s)
  Li Zan, 大野　みずき, 鷹野典子, 佐々木史子, 日高京子, 中津可道, 續輝久
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] MUTYH欠損マウスを用いた酸化ストレス誘発消化管がんと体細胞突然変異の解析2015
- Author(s)
  鷹野典子, 大野　みずき, 佐々木史子, 山内一己, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] MUTYH欠損マウスを用いた酸化ストレス誘発消化管がんと体細胞突然変異の解析2015
- Author(s)
  鷹野典子、大野みずき、佐々木史子、中別府雄作、日高京子、中津可道、續輝久
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  福岡（九州大学コラボ・ステーションI・II）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] ミスマッチ修復欠損マウスにおける生殖細胞ゲノム変異の解析2015
- Author(s)
  大野　みずき, 鷹野典子, 佐々木史子, 日高京子, 中津可道, 續輝久
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Trp53欠損マウスにおける酸化ストレス誘発消化管がんの解析2015
- Author(s)
  李賛、大野みずき、鷹野典子、佐々木史子、日高京子、中津可道、續輝久
- Organizer
  日本環境変異原学会第44回大会
- Place of Presentation
  福岡（九州大学コラボ・ステーションI・II）
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 生殖細胞自然突然変異の新規発生と変異アリールの伝達2015
- Author(s)
  作見邦彦, 大野　みずき, 古市正人, 續輝久, 中別府雄作
- Organizer
  日本環境変異原学会
- Place of Presentation
  福岡
- Year and Date
  2015-11-27
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Mismatch Repair Deficient Mice Show Susceptibility to Oxidative Stress-induced Intestinal Carcinogenesis2015
- Author(s)
  Yoshimich Nakatsu, Jingshu Piao, Takuya Hashizume, Mizuki Ohno, Kenichi Taguchi, Teruhisa Tsuzuki
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto（京都国際会議場）
- Year and Date
  2015-05-25
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Role of the oxidative DNA damage repair system in somatic and germline mutations in mice2015
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  Zing conference "Genome Integrity"
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-07-31
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] 酸化ストレス誘発消化管発がんと突然変異の抑制におけるMUTYHの役割2015
- Author(s)
  大野みずき、鷹野典子、中津可道、中別府雄作、續輝久
- Organizer
  日本癌学会第74回学術総会
- Place of Presentation
  名古屋（名古屋国際会議場）
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Mutyh欠損マウスを用いた酸化ストレス誘発突然変異と発がんの解析2015
- Author(s)
  鷹野典子、大野みずき、佐々木史子、山内一己、中別府雄作、中津可道、續輝久
- Organizer
  日本分子生物学会第38回年会・日本生化学会第88回大会合同大会
- Place of Presentation
  神戸（神戸国際会議場）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Influence of Oxidative DNA Damage on the Rate of Somatic and Germline Mutation2015
- Author(s)
  Ohno M, Takano N, Sakumi K, Fukumura R, Iwasaki Y, Ikemura T, Gondo Y, Nakabepppu Y, Nakatsu Y, Tsuzuki T
- Organizer
  15th International Congress of Radiation Research (ICRR2015)
- Place of Presentation
  Kyoto International Conference Center,Kyoto, Japan
- Year and Date
  2015-05-27
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25241016
[Presentation] MUTYH欠損マウスを用いた酸化ストレス誘発消化管がんと体細胞突然変異の解析2015
- Author(s)
  鷹野典子, 大野　みずき, 佐々木史子, 山内一己, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] 次世代ゲノム遺伝情報維持におけるミスマッチ修復の役割2015
- Author(s)
  大野みずき, 鷹野典子, 佐々木史子, 中津可道, 續輝久
- Organizer
  日本遺伝学会
- Place of Presentation
  仙台
- Year and Date
  2015-09-24
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] 酸化ストレス誘発消化管発がんと突然変異の抑制におけるMUTYHの役割2015
- Author(s)
  大野みずき, 鷹野典子, 中津可道, 中別府雄作, 續輝久
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2015-10-08
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] DNA酸化損傷修復欠損マウスの継代実験で捉えられた遺伝現象2014
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩崎裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜市長浜バイオ大学
- Year and Date
  2014-09-17
- Invited
- Data Source
  KAKENHI-PROJECT-25241016
[Presentation] 8-Oxoguanine causes spontaneous de novo germline mutations : a study from the mutator mouse line2014
- Author(s)
  大野みずき, 作見邦彦, 福村　龍太郎, 岩崎　裕貴, 池村　淑道, 續輝久, 権藤　洋一, 中別府雄作
- Organizer
  SMBE Satellite Meeting / NIG International Symposium
- Place of Presentation
  静岡　三島
- Invited
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] Oxidation of nucleic acids and control mechanisms of genetic diversity in mammals2014
- Author(s)
  中別府雄作, 大野みずき, 福村　龍太郎, 岩崎　裕貴, 池村　淑道, 権藤　洋一, 作見邦彦
- Organizer
  International Symposium on Germline Mutagenesis and Biodiversification
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] 8-oxoguanineに起因して新たに生じた生殖細胞突然変異の解析2014
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩崎裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜市パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25241016
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析2013
- Author(s)
  大野みずき, 作見邦彦, 福村　龍太郎, 権藤　洋一, 岩崎　裕貴, 池村　淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会　第８５回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] 活性酸素による核酸の酸化と哺乳動物における遺伝子多様性の制御機構2013
- Author(s)
  中別府雄作, 大野みずき, 作見邦彦
- Organizer
  日本遺伝学会　第８５回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析 (II)2013
- Author(s)
  作見邦彦, 大野みずき, 福村　龍太郎, 権藤　洋一, 岩崎　裕貴, 池村　淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会　第８５回大会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] 8-オキソグアニンの修復機構を欠損するマウスは、生殖細胞ゲノム中の突然変異頻度の上昇と遺伝性の変異形質を呈する2012
- Author(s)
  大野みずき
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 酸化損傷塩基の修復機構を欠損するマウス家系の解析2012
- Author(s)
  大野みずき
- Organizer
  第３５回日本分子生物学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 酸化損傷塩基の修復機構は生殖細胞ゲノム変異を抑制し同系交配によるマウスの表現型の安定性に寄与する2012
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、續輝久、中別府雄作
- Organizer
  日本環境変異原学会第41回大会
- Place of Presentation
  静岡
- Year and Date
  2012-11-29
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] Influence of 8-oxoguanine on mitotic and meiotic chromosome2012
- Author(s)
  Mizuki Ohno, Kunihiko Sakumi, Teruhisa Tsuzuki, Yusaku Nakabeppu
- Organizer
  The 10th International Symposium on Chromosomal Aberrations
- Place of Presentation
  Italia
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] Influence of 8-oxoguanine on mitotic and meiotic chromosome2012
- Author(s)
  Mizuki Ohno
- Organizer
  The 10th International Symposium on Chromosomal Aberrations
- Place of Presentation
  イタリア
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] ワークショップ8-オキソグアニンの修復機構を欠損するマウスは、生殖細胞ゲノム中の突然変異頻度の上昇と遺伝性の変異形質を呈する2012
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、續輝久、中別府雄作
- Organizer
  日本遺伝学会第84回大会
- Place of Presentation
  福岡
- Year and Date
  2012-09-25
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 酸化損傷塩基の修復機構を欠損するマウス家系の解析2012
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、田口健一、續輝久、中別府雄作
- Organizer
  第35回日本分子生物学会
- Place of Presentation
  福岡
- Year and Date
  2012-12-15
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] A study of radiation-induced oxidative DNA damage and its repair in mouse intestine2011
- Author(s)
  大野みずき, 中西恵美, 績輝久
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] Astudy of radiation- induced oxidative DNA damage and its repair in mouse intestine2011
- Author(s)
  Mizuki Ohno, Megumi Nakanishi, Teruhisa Tsuzuki
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  横浜
- Year and Date
  2011-12-15
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 8-oxoguanineはDNA鎖切断を誘発することで減数分裂期の相同染色体組換え頻度を上昇させる2011
- Author(s)
  大野みずき, 作見邦彦, 古市正人, 中西恵美, 績輝久, 中別府雄作
- Organizer
  日本遺伝学会第83会大会
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] A study of radiation-induced oxidative DNA damage and its repair in mouse tissues2011
- Author(s)
  Mizuki Ohno, Megumi Nakanishi, Teruhisa Tsuzuki
- Organizer
  14th International Congress of Radiation Research
- Place of Presentation
  ワルシャワ
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] A study of radiation- induced oxidative DNA damage and its repair in mouse tissues2011
- Author(s)
  Mizuki Ohno, Megumi Nakanishi, Teruhisa Tsuzuki
- Organizer
  14th Inter- national Congress of Radiation Research
- Place of Presentation
  Poland
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] マウス小腸における放射線誘発酸化損傷塩基の解析2011
- Author(s)
  大野みずき、中西恵美、續埋久
- Organizer
  日本放射線影響学会
- Place of Presentation
  神戸
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] マウス腸管における放射線誘発酸化DNA損傷の解析2011
- Author(s)
  大野みずき, 中西恵美, 績輝久
- Organizer
  日本環境変異学会第40回大会
- Place of Presentation
  東京
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] マウス小腸における放射線誘発酸化損傷塩基の解析2011
- Author(s)
  大野みずき、中西恵美、績輝久
- Organizer
  日本放射線影響学会第52大会
- Place of Presentation
  神戸
- Year and Date
  2011-11-17
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 8-oxoguanineはDNA鎖切断を誘発することで減数分裂期の相同染色体組換え頻度を上昇させる2011
- Author(s)
  大野みずき,作見邦彦,古市正人,中西恵美,續輝久,中別府雄作
- Organizer
  日本遺伝学会
- Place of Presentation
  京都
- Year and Date
  2011-09-21
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] マウス腸管における放射線誘発酸化DNA損傷の解析2011
- Author(s)
  大野みずき,中西恵美,續輝久
- Organizer
  日本環境変異学会
- Place of Presentation
  東京
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 酸化損傷DNAが生殖細胞ゲノムに及ぼす影響2010
- Author(s)
  大野みずき、作見邦彦、古市正人、中別府雄作、續輝久
- Organizer
  日本環境変異原学会39回大会
- Place of Presentation
  筑波国際会議場(茨城)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 8-oxoguanineはDNA鎖切断を誘発することで減数分裂期の相同染色体組換え頻度を上昇させる2010
- Author(s)
  大野みずき、作見邦彦、續輝久、中別府雄作
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 8-oxoguanineはDNA鎖切断を誘発することで減数分裂期の相同染色体組換え頻度を上昇させる2010
- Author(s)
  大野みずき、作見邦彦、續輝久、中別府雄作
- Organizer
  日本分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫)
- Year and Date
  2010-12-08
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 酸化損傷DNAが生殖細胞ゲノムに及ぼす影響2010
- Author(s)
  大野みずき、中西恵美、作見邦彦、古市正人、中別府雄作、續輝久
- Organizer
  日本環境変異原学会
- Place of Presentation
  筑波
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 酸化損傷DNAが生殖細胞ゲノムに及ぼす影響2010
- Author(s)
  大野みずき、作見邦彦、古市正人、中別府雄作、續輝久
- Organizer
  日本環境変異原学会39回大会
- Place of Presentation
  筑波国際会議場(茨城)
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 低LET放射線による核酸の損傷とその修復機構:腸管と精巣における解析2010
- Author(s)
  大野みずき、中西恵美、中津河道、續輝久
- Organizer
  日本放射線影響学会
- Place of Presentation
  京都
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 低LET放射線による核酸の損傷とその修復機構:腸管と精巣における解析2010
- Author(s)
  大野みずき、中西恵美、中津可道、續輝久
- Organizer
  放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-22300144
[Presentation] 低LET放射線による核酸の損傷とその修復機構:腸管と精巣における解析2010
- Author(s)
  大野みずき、中西恵美、中津可道、續輝久
- Organizer
  放射線影響学会第53回大会
- Place of Presentation
  京都テルサ(京都)
- Year and Date
  2010-10-20
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 酸化的DNA損傷と生殖細胞ゲノム変異2009
- Author(s)
  大野みずき, 他
- Organizer
  日本放射線影響学会第52回大会
- Place of Presentation
  広島
- Year and Date
  2009-11-12
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 酸化損傷塩基の修復能を欠損するマウスにおける継世代的影響の解析2009
- Author(s)
  大野みずき, 他
- Organizer
  日本遺伝学会第81回大会
- Place of Presentation
  長野
- Year and Date
  2009-09-17
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 酸化的DNA損傷に起因する染色体変異とその抑制機構2009
- Author(s)
  大野みずき, 他
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20012037
[Presentation] 酸化的DNA損傷と生殖細胞ゲノム変異2009
- Author(s)
  大野みずき, 他
- Organizer
  日本環境変異学会第38回大会
- Place of Presentation
  静岡
- Data Source
  KAKENHI-PROJECT-20012037
[Presentation] 8-Oxoguanine promotes homologous recombination in mammalian cells2009
- Author(s)
  大野みずき, 他
- Organizer
  ASM DNA repair and mutagenesis
- Place of Presentation
  カナダ
- Year and Date
  2009-06-02
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 酸化損傷塩基の修復能を欠損するマウスにおける継世代的影響の解析2009
- Author(s)
  大野みずき, 他
- Organizer
  日本遺伝学第81回大会
- Place of Presentation
  長野
- Data Source
  KAKENHI-PROJECT-20012037
[Presentation] 酸化的DNA損傷に起因する染色体変異とその抑制機構2009
- Author(s)
  大野みずき, 他
- Organizer
  弟32回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2009-12-10
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 酸化的DNA損傷と生殖細胞ゲノム変異2009
- Author(s)
  大野みずき, 他
- Organizer
  日本環境変異原学会
- Place of Presentation
  静岡
- Year and Date
  2009-11-27
- Data Source
  KAKENHI-PROJECT-21657002
[Presentation] 酸化的DNA損傷と生殖細胞ゲノム変異2009
- Author(s)
  大野みずき, 他
- Organizer
  日本放射線影響学会第52大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-20012037
[Presentation] ミューテーターマウス家系を用いた生殖細胞突然変異の解析システム
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-25241016
[Presentation] Oxidative stress-induced mutagenesis and tumorigenesis in the small intestine of Mutyh-deficient mice treated with low doses of potassium bromate
- Author(s)
  Mizuki Ohno, Noriko Takano, Yoshimichi Nakatsu, Yusaku Nakabeppu, Teruhisa Tsuzuki
- Organizer
  日本癌学会第73回学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] DNA酸化損傷修復欠損マウスの継代実験で捉えられた遺伝現象
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩﨑裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜
- Year and Date
  2014-09-16 – 2014-09-18
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] 酸化ストレス誘発突然変異と消化管がんの解析
- Author(s)
  大野みずき, 鷹野典子, 佐々木史子, 李贊, 田口健一, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] Role of the oxidative DNA damage repair system in somatic and germline mutations in mice
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu,Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  Zing conference Genomic integlity
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-01 – 2015-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] 8-Oxoguaninecauses spontaneous de novo germline mutations: a study from the mutator mouse lines
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  SMBE Satellite Meeting / NIG International Symposium
- Place of Presentation
  三島市
- Invited
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-25241016
[Presentation] 酸化DNA損傷と消化管がん
- Author(s)
  大野みずき、中津可道、中別府雄作、續輝久
- Organizer
  日本分子生物学会第34回年会
- Place of Presentation
  神戸国際会議場
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Mutyh欠損マウスにおける酸化ストレス誘発発がんおよび突然変異の解析
- Author(s)
  鷹野典子, 大野みずき, 中別府雄作, 中津可道, 續輝久
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 8-oxoguanineに起因して新たに生じた生殖細胞突然変異の解析
- Author(s)
  作見邦彦, 大野みずき, 福村　龍太郎, 権藤　洋一, 岩﨑裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] Oxidative stress -induced tumorigenesis in the small intestine of Mutyh-deficient mouse
- Author(s)
  大野みずき, 鷹野典子, 中津可道, 中別府雄作, 續輝久
- Organizer
  第73回日本癌学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2014-09-26 – 2014-09-28
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] Oxidative DNA damage and its repair system: implications for de novo germline mutations
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsua, Teruhisa Tsuzuki
- Organizer
  Genome Integlity, Zing Conference
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-01 – 2015-08-05
- Invited
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] DNA酸化損傷修復欠損マウスの継代実験で捉えられた遺伝現象
- Author(s)
  作見邦彦, 大野みずき, 福村龍太郎, 権藤洋一, 岩﨑裕貴, 池村淑道, 續輝久, 中別府雄作
- Organizer
  日本遺伝学会第86回大会
- Place of Presentation
  長浜
- Year and Date
  2014-09-17 – 2014-09-19
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Mutyh遺伝子欠損マウスを用いた酸化ストレス誘発消化管がんの解析
- Author(s)
  大野みずき、鷹野典子、佐々木史子、田口健一、中別府雄作、青木康展、能美健彦、中津可道、續輝久
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  東京
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Influence of oxidative DNA damage on the rate of somatic and germline mutation
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu,Yoshimichi Nakatsu, Teruhisa Tsuzuki
- Organizer
  15th International Congress of Radiation Research
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2015-05-25 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-26281022
[Presentation] Oxidative stress-induced intestinal tumors in Mutyh-deficient mice treated with low doses of potassium bromate
- Author(s)
  Teruhisa Tsuzuki, Mizuki Ohno, Noriko Takan1, Kenichi Taguchi, Yusaku Nakabeppu, Yasunobu Aoki, Takehiko Nohmi, Yoshimichi Nakatsu
- Organizer
  5th US-Japan DNA Repair Meeting
- Place of Presentation
  Tokushima
- Year and Date
  2014-10-28 – 2014-10-31
- Invited
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析 II
- Author(s)
  作見邦彦、大野みずき、福村太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応義塾大学・日吉キャンパス（横浜市）
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Oxidative DNA damage and its repair system: implications for de novo germline mutations
- Author(s)
  Mizuki Ohno
- Organizer
  第37回日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] Oxidative stress-induced tumorigenesis in the small intestine of Mutyh-deficient mice: the effect of low-level exposure to KBrO3
- Author(s)
  Teruhisa Tsuzuki, Mizuki Ohno, Yusaku Nakabeppu, Yoshimich Nakatsu
- Organizer
  日本癌学会第72回学術総会, Symposium 21: Biological Effects of Ionizing Radiation and Genotoxic Chemotherapeutic Agents
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 8-Oxoguanin causes spontaneous de novo germline mutations: A study from the mutator mouse line.
- Author(s)
  Ohno M, Sakumi K, Fukumura R, Iwasaki Y, Ikemura T, Tsuzuki T, Gondo Y, Nakabeppu Y
- Organizer
  SMBE Satellite Meeting/NIG International Symposium: The Cause of Genome Evolution
- Place of Presentation
  Mishima, Japan
- Invited
- Data Source
  KAKENHI-PROJECT-25241016
[Presentation] ミスマッチ修復欠損マウスにおける酸化ストレス誘発突然変異の解析
- Author(s)
  橋詰拓弥、中津可道、大野みずき、佐々木史子、鷹野典子、續輝久
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] ミューテーターマウス家系を用いた生殖細胞突然変異の解析システム
- Author(s)
  大野みずき、作見邦彦、福村龍太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  日本環境変異原学会第42回大会
- Place of Presentation
  岡山コンベンションセンター
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 8-oxoguanine に起因するde novo germline mutation の解析
- Author(s)
  大野みずき、福村龍太郎、権藤洋一、岩﨑裕貴、池村淑道、續輝久、中別府作
- Organizer
  日本分子生物学会第37回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] In vitro study for mutagenicity of purple rice hull extract using fibroblasts derived from rpsL-transgenic mouse
- Author(s)
  Charatda Punvittayagul, Yoshimichi Nakatsu, Rawiwan Wongpoomchai, Mizuki Ohno, Teruhisa Tsuzuki
- Organizer
  日本癌学会第72回学術総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 酸化ストレス誘発突然変異と消化管がん解析
- Author(s)
  大野みずき、鷹野典子、佐々木史子、橋詰拓弥、李賛、田口健一、中別府雄作、中津可道、續輝久
- Organizer
  日本放射線影響学会第57回大会
- Place of Presentation
  鹿児島
- Year and Date
  2014-10-01 – 2014-10-03
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Influence of oxidative DNA damage on the rate of somatic and germline mutation
- Author(s)
  Mizuki Ohno, Noriko Takano, Kunihiko Sakumi, Ryutaro Fukumura, Yuki Iwasaki, Toshimichi Ikemura, Yoichi Gondo, Yusaku Nakabeppu, Yoshimichi Nakatsu, Teruhisa Tsuzuk
- Organizer
  International Congress of Radiation Research
- Place of Presentation
  Kyoto
- Year and Date
  2015-05-25 – 2015-05-29
- Data Source
  KAKENHI-PROJECT-25650130
[Presentation] Mutyh遺伝子欠損マウスにおける酸化ストレス誘発突然変異の解析
- Author(s)
  鷹野典子、大野みずき、稲葉洋平、志村勉、欅田尚樹、中別府雄作、中津可道、續輝久
- Organizer
  日本環境変異原学会第43回大会
- Place of Presentation
  東京
- Year and Date
  2014-12-04 – 2014-12-05
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Mutyh遺伝子欠損マウスにおける酸化ストレス誘発突然変異の解析
- Author(s)
  鷹野典子、大野みずき、稲葉洋平、志村勉、欅田尚樹、中別府雄作、中津可道、續輝久
- Organizer
  日本分子生物学会第37回年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] Oxidative stress-induced intestinal tumors in Mutyh-deficient mice treated with low doses of potassium bromate
- Author(s)
  Teruhisa Tsuzuki, Mizuki Ohno, Noriko Takano, Kenichi Taguchi, Yusaku Nakabeppu, Yasunobu Aoki, Takehiko Nohmi, Yoshimichi Nakatsu
- Organizer
  4th Asian Conference on Environmental Mutagen
- Place of Presentation
  Kolkata, India
- Year and Date
  2014-12-10 – 2014-12-12
- Invited
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析
- Author(s)
  大野みずき、作見邦彦、福村太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  慶応義塾大学・日吉キャンパス（横浜市）
- Data Source
  KAKENHI-PROJECT-25241012
[Presentation] 酸化DNA 損傷に起因するde novo germline mutationの解析II
- Author(s)
  作見邦彦、大野みずき、福村龍太郎、権藤洋一、岩崎裕貴、池村淑道、續輝久、中別府雄作
- Organizer
  日本遺伝学会第85回大会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-25241016

1. TSUZUKI Teruhisa (40155429)

# of Collaborated Projects: 6 results

# of Collaborated Products: 89 results
2. NAKATSU Yoshimichi (00207820)

# of Collaborated Projects: 4 results

# of Collaborated Products: 33 results
3. 日高京子 (00216681)

# of Collaborated Projects: 4 results

# of Collaborated Products: 22 results
4. SAKUMI KUNIHIKO (50211933)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. 鷹野典子 (30840318)

# of Collaborated Projects: 3 results

# of Collaborated Products: 30 results
6. Gondo Yoichi (40225678)

# of Collaborated Projects: 2 results

# of Collaborated Products: 7 results
7. 岡素雅子 (80467894)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. YAO Takashi (20243933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. AOKI Yasunobu (20159297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 日高真純 (80238310)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
11. 姫野龍太郎 (60342838)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 茶野徳宏 (40346028)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 舘田英典 (70216985)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 野原恵子 (50160271)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 松本理 (60132867)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 手島康介 (20447593)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 坂東昌子 (20025365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 山内一己 (40415419)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 香崎正宙 (90717977)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 近藤琢也 (00644725)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 永田公二 (20419568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 張秀英 (50914173)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 田尻達郎 (80304806)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 内村有邦 (20513063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
25. 松本義久 (20302672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MASUMURA Kenichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. HIGUCHI Mayumi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 中別府雄作

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. 西昭徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 大西克典

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohno Mizuki 大野 みずき

OHNO Mizuki 大野 みずき

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卵子が持つ精子DNA損傷を修復する能力の分子機構解明と次世代ゲノム影響の解析Principal Investigator

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Understanding molecular mechanism behind the oocyte's DNA repair ability of sperm genome damagePrincipal Investigator

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Analysis of de novo germline mutations by using environmental genome stress-sensitive micePrincipal Investigator

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The role of non-S DNA synthesis on the local mutation ratePrincipal Investigator

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Study of molecular mechanisms of germline mutation by using DNA repair deficient micePrincipal Investigator

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DNA修復欠損マウスを用いたエピミューテーションの解析Principal Investigator

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Ohno Mizuki 大野みずき

OHNO Mizuki 大野みずき

[Book] 日本臨牀（増刊号）最新臨床大腸癌学基礎研究から臨床応用へ2015