FUJITA Ryousuke 藤田亮介

Researcher Number	70380855
Affiliation (based on the past Project Information) *help	2009: 長崎大, 医歯(薬)学総合研究科, 助教 2007 – 2009: Nagasaki University, 大学院・医歯薬学総合研究科, 助教 2005 – 2006: 長崎大学, 大学院医歯薬学総合研究科, 助手 2004 – 2005: Nagasaki University, Graduate School of Biomedical Sciences, Research Associate, 大学院・医歯薬学総合研究科, 助手
Review Section/Research Field	Principal Investigator Neurochemistry/Neuropharmacology / General pharmacology / Biological pharmacy Except Principal Investigator Biological Sciences / Environmental pharmacy / Biological pharmacy / Pain science / Anesthesiology/Resuscitation studies
Keywords	Principal Investigator プロサイモシンアルファー / 神経細胞 / グルコース / ミクログリア / アポトーシス / プロサイモシンアルファー / 脳卒中 / 海洋微生物ライブラリー / ネクローシス / 生理活性物質 … More / アストロサイト / シナプトタグミン / FRET / カルシウムイオン / cell death mode switch / apoptosis / necrosis / ProTα / S100A13 / TAT / FGF-1 / 非小胞性遊離機構 … More Except Principal Investigator MAP2 / 神経ステロイド / ストレス / tubulin / WGA / グルココルチコイド / HPA axis / ナノメディシン / ストレス性精神疾患 / NDI / STI / Ca^<2+> / FGF-1 / S100A13 / スパイン / アクチン / スプラウティング / リゾホスファチジン酸 / 脱髄 / 神経因性疼痛 / FRAP / Tashiro's carbonless medium / microorganism library / source of carbon / clean-up of waters / contamination / microorganism / endocrine disrupting chemicals / 無機培地 / ライブラリー / 炭素源 / 無毒化 / 汚染 / 微生物 / 環境ホルモン / serum starvation / non-vesicular release / Stress / S100 / 低酸素 / 核移行 / 分泌 / ネクローシス / 神経細胞死 / 無血清 / non-classical release / BDNF / Eph / Cre-loxP / プロサイモシンアルファー / LTP / WGA-EGFP / コルチコステロン / ex vivo培養 / 電子顕微鏡 / ミエリン関連タンパク質 / シュワン細胞 / 脱髄 / Ramak束 / ミエリンタンパク質 / アロディニア / MAG / 神経可塑性 / シナプス / 微小管 / 麻薬依存ストレス変調 / プロサイモシンアルファー / 虚血性神経変性疾患 / 神経ネットワーク可視化 / Tubulin / 神経因性疹痛 / 神経発芽 / LPA産生 / ex vivo解析 / LPA合成酵素 / ミエリン蛋白質 / Mass imaging / 線維筋痛症 / LPA de novo合成 / 脊髄損傷 / WGAトランスジーン法 / 神経回路 / 脂質 / 脳・神経 / QCM法 / X線結晶化構造解析 / 樹状突起 / 微小管制御ナノシステム Less

新しい脳卒中標的としての神経ネクローシス-プロサイモシンアルファと創薬基礎研究Principal Investigator
- Principal Investigator
  
  藤田亮介
- Project Period (FY)
  2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagasaki University
ストレス性精神疾患の可視化とナノメディシン
- Principal Investigator
  
  植田弘師
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
神経極性を形づくる微小管重合を制御する神経ステロイド
- Principal Investigator
  
  植田弘師
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
Research on the allodynia-involved sprouting mechanisms
- Principal Investigator
  
  UEDA Mutsumi
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pain science
- Research Institution
  Nagasaki University
Research of ischemic damage prevention by prothymosin alpha and screening of anti-necrosis factor from marine microbes laibraryPrincipal Investigator
- Principal Investigator
  
  FUJITA Ryousuke
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General pharmacology
- Research Institution
  Nagasaki University
ストレス性精神疾患の可視化とナノメディシン
- Principal Investigator
  
  植田弘師
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
ストレス性精神疾患の可視化とナノメディシン
- Principal Investigator
  
  UEDA Hiroshi
- Project Period (FY)
  2005
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
神経極性を形づくる微小管重合を制御する神経ステロイド
- Principal Investigator
  
  植田弘師
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Nagasaki University
Identification of molecular targets to cure intractable neuropathic pain with nerve injury-induced demyelination
- Principal Investigator
  
  UEDA Hiroshi
- Project Period (FY)
  2005 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (S)
- Research Field
  
  Anesthesiology/Resuscitation studies
- Research Institution
  Nagasaki University
ストレス誘発性小胞分泌機構の解明-HIVウイルス蛋白質TAT遊離の分子基盤Principal Investigator
- Principal Investigator
  
  藤田亮介
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagasaki University
Functional proteomics analysis of non-vesicular release mechanisms in stress exposed neuron-role of stress-induced non-vesicular release Prion, NDI and FGF-1 in neuron
- Principal Investigator
  
  UEDA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Nagasaki University
Preparation of microorganism library derived from soils of seacoast, river and lakes, and its utilization for the environmental clean-up from endocrine disrupting chemicals.
- Principal Investigator
  
  UEDA Hiroshi
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  Nagasaki University

All 2009 2008 2007

All Journal Article Presentation

[Journal Article] Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition2009
- Author(s)
  Fujita R., Ueda M., Fujiwara K. & Ueda H.
- Journal Title
  
  Cell Death & Differentiation 16
  
  Pages: 349-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790191
[Journal Article] Prothymosin-alphal plays a defensive role in retinal ischemia thro ugh necrosis and apoptosis inhibition2009
- Author(s)
  Ryousuke Fujita
- Journal Title
  
  Cell Death & Differentiation 16
  
  Pages: 349-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20023022
[Journal Article] Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition2009
- Author(s)
  Ryousuke Fujita
- Journal Title
  
  Cell Death & Differentiation 16
  
  Pages: 349-358
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790191
[Journal Article] Lysophosphatidic acid-induced membrane ruffling and brain-derived neurotrophic factor gene expression are mediated by ATP release in primary microglia2008
- Author(s)
  Fujita R, Ma Y, Ueda H
- Journal Title
  
  J. Neurochem 107(1)
  
  Pages: 152-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603008
[Journal Article] Lysophosphtidic acid-induced membrane ruffling and brain-derived neurotropic factor gene expression are mediated by ATP release in primary microglia2008
- Author(s)
  Ryousuke Fujita
- Journal Title
  
  Journal of Neurochemistry 107
  
  Pages: 152-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19603008
[Journal Article] Lysophosphtidic acid-induced membrane ruffling and brain-derived neurotropic factor gene expression are mediated by ATP release in primary microglia2008
- Author(s)
  Ryousuke Fujita
- Journal Title
  
  Journal of Neurochemistry 107
  
  Pages: 152-160
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109015
[Journal Article] Lysophosphatidic acid-induced membrane ruffling and BDNF gene expression are mediated by ATP release in primary microglia.2008
- Author(s)
  Fujita R, Ma Y, Ueda H.
- Journal Title
  
  J Neurochem 107(1)
  
  Pages: 152-60
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109015
[Journal Article] LPA-mediated demyelination in ex vivo culture of dorsal root.2007
- Author(s)
  Fujita R, Kiguchi N, Ueda H.
- Journal Title
  
  Neurochem Int. 50(2)
  
  Pages: 351-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17109015
[Journal Article] LPA-mediated demyelination in ex vivo culture of dorsal root.2007
- Author(s)
  Fujita R
- Journal Title
  
  Neurochem Int 50
  
  Pages: 351-355
- Data Source
  KAKENHI-PROJECT-17109015
[Journal Article] Prothymosin-alpha1 prevents necrosis and apoptosis following stroke2007
- Author(s)
  Fujita R. & Ueda H.
- Journal Title
  
  Cell Death & Differentiation 14
  
  Pages: 1839-1842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790191
[Journal Article] Prothymosin-alphal prevents necrosis and apoptosis following stroke.2007
- Author(s)
  Ryousuke Fujita
- Journal Title
  
  Cell Death & Differentiation 14
  
  Pages: 1839-1842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790191
[Journal Article] Prothymosin-alphal prevents necrosis and apoptosis following stroke.2007
- Author(s)
  Ryousuke Fujita
- Journal Title
  
  Cell Death & Differentiation 14
  
  Pages: 1839-1842
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18023028
[Presentation] PET解析を用いたProthymosin-αによるPKCβ活性化を介したグルコース取込み促進2008
- Author(s)
  藤田亮介、水間広、和田康弘、渡辺恭良、植田弘師
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] 神経細胞におけるProthymosin αによるPKCβを介したGLUT4膜移行促進機構の解明2008
- Author(s)
  藤村一輝、畠山有理、藤田亮介、植田弘師
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] プロサイモシン・アルファによるPKCβを介した虚血神経ネクローシス抑制とPET解析2008
- Author(s)
  藤田亮介
- Organizer
  第114会日本薬理学会近畿部会
- Place of Presentation
  神戸
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-20023022
[Presentation] 脳卒中治療薬としてのProthymosin αの可能性2008
- Author(s)
  神崎めぐみ、高濱和弘、藤田亮介、植田弘師
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin αによるPKCβを介した初代培養ミクログリアの活性化2008
- Author(s)
  植村朋香、藤田亮介、植田弘師
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Identification of prothymosin-alpha, the necrosis-apoptosis switch molecule in the cortical neuron culture.2008
- Author(s)
  藤田亮介
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-18023028
[Presentation] Identification of prothymosin-alpha, the necrosis-apoptosis switch molecule in the cortical neuron culture.2008
- Author(s)
  藤田亮介
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] プロサイモシン・アルファによるPKCβを介した虚血神経ネクローシス抑制とPET解析2008
- Author(s)
  藤田亮介
- Organizer
  第114会日本薬理学会近畿部会
- Place of Presentation
  神戸
- Year and Date
  2008-11-14
- Data Source
  KAKENHI-PROJECT-17109015
[Presentation] Identification of prothymosin-alpha, the necrosis-apoptosis switch molecule in the cortical neuron culture2008
- Author(s)
  藤田亮介、植田弘師
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin αによる虚血依存的なミクログリア活性化2008
- Author(s)
  米窪沙織、藤田亮介、植田弘師
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] 新規脳保護分子Prothymosin αによるラット一過性脳卒中傷害の改善2008
- Author(s)
  山崎達朗、藤田亮介、植田弘師
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin α prevents necrosis and apoptosis following stroke2008
- Author(s)
  米窪沙織、藤田亮介、植田弘師
- Organizer
  第81回日本薬理学会年会
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2008-03-17
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] PET解析を用いたProthymosin-αによるPI(Cβ活性化を介したグルコース取込み促進2008
- Author(s)
  藤田亮介
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸ポートアイランド(神戸市)
- Year and Date
  2008-12-11
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin-alpha1 prevents neuronal necrosis by reversing the decreased membrane localization of GLUT2007
- Author(s)
  Fujita R. and Ueda H.
- Organizer
  Neuroscience 2007
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin-alphal prevents neuronal necrosis by reversing the decreased membrane localization of GLUT2007
- Author(s)
  Ryousuke Fujita
- Organizer
  Neuroscience 2007
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Identification of prothymosin-alpha1, the necrosis-apoptosis switch molecule under the in vitro ischemia condition2007
- Author(s)
  Ueda H., Fujita R., Matsunaga H., Yoshida A. and Ueda M.
- Organizer
  Neuroscience 2007
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Identification of prothymosin-alpha1, the necrosis-apoptosis switch molecule under the in vitro ischemia condition2007
- Author(s)
  Ueda H., Fujita R., Matsunaga H., Yoshida A. and Ueda M.
- Organizer
  第5回国際受容体シンポジウム(IRS2007)
- Place of Presentation
  静岡コンベンションアーツセンター(静岡市)
- Year and Date
  2007-05-10
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin-alphal prevents neuronal necrosis by reversing the decreased membrane localization of GLUT2007
- Author(s)
  Ryousuke Fujita
- Organizer
  Neuroscience 2007
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2007-11-05
- Data Source
  KAKENHI-PROJECT-18023028
[Presentation] 虚血脳に対するプロサイモシンαのネクローシス保護機構2007
- Author(s)
  早田知永、高濱和弘、藤田亮介、植田弘師
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  シーガイア(宮崎市)
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] 神経ネクローシス保護分子プロサイモシンα2007
- Author(s)
  藤田亮介
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  シーガイア(宮崎市)
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-18023028
[Presentation] Prothymosin-alpha1 switches from an uncontrollable necrosis to a controllable apoptosis2007
- Author(s)
  Takahama K., Fujita R. and Ueda H.
- Organizer
  Neuroscience 2007
- Place of Presentation
  サンディエゴ(米国)
- Year and Date
  2007-11-03
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin-alpha1 switches from an uncontrollable necrosis to a controllable apoptosis2007
- Author(s)
  高濱和弘、藤田亮介、植田弘師
- Organizer
  Neuro 2007
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] マウス一過性中大脳動脈閉塞再灌流モデルにおけるプロサイモシンαの脳保護効果2007
- Author(s)
  高濱和弘、藤田亮介、植田弘師
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  シーガイア(宮崎市)
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin-alphal prevents neuronal necrosis by reversing the decreased membrane localization of GLUT2007
- Author(s)
  藤田亮介
- Organizer
  Neuro 2007
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-18023028
[Presentation] Prothymosin-alphal prevents neuronal necrosis by reversing the decreased membrane localization of GLUT2007
- Author(s)
  藤田亮介
- Organizer
  Neuro 2007
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] 神経ネクローシス保護分子プロサイモシンα2007
- Author(s)
  藤田亮介、植田弘師
- Organizer
  第60回日本薬理学会西南部会
- Place of Presentation
  シーガイア(宮崎市)
- Year and Date
  2007-11-22
- Data Source
  KAKENHI-PROJECT-19790191
[Presentation] Prothymosin-alpha1 prevents neuronal necrosis by reversing the decreased membrane localization of GLUT2007
- Author(s)
  藤田亮介、植田弘師
- Organizer
  Neuro 2007
- Place of Presentation
  パシフィコ横浜(横浜市)
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19790191

1. INOUE Makoto (60380987)

# of Collaborated Projects: 9 results

# of Collaborated Products: 0 results
2. UEDA Hiroshi (00145674)

# of Collaborated Projects: 8 results

# of Collaborated Products: 2 results
3. UEDA Mutsumi (30437834)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
4. UCHIDA Hitoshi (30549621)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 水野恭伸 (40311865)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 吉田明 (70257187)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SUMIKAWA Koji (60028660)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SAKAGUCHI Suehiro (60274635)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 芳本忠 (60088870)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

FUJITA Ryousuke 藤田 亮介

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Co-Researchers

新しい脳卒中標的としての神経ネクローシス-プロサイモシンアルファと創薬基礎研究Principal Investigator

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Research of ischemic damage prevention by prothymosin alpha and screening of anti-necrosis factor from marine microbes laibraryPrincipal Investigator

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ストレス誘発性小胞分泌機構の解明-HIVウイルス蛋白質TAT遊離の分子基盤Principal Investigator

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[Journal Article] Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition2009

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[Journal Article] Prothymosin-alphal plays a defensive role in retinal ischemia thro ugh necrosis and apoptosis inhibition2009

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[Journal Article] Prothymosin-alpha plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition2009

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[Journal Article] Lysophosphatidic acid-induced membrane ruffling and brain-derived neurotrophic factor gene expression are mediated by ATP release in primary microglia2008

FUJITA Ryousuke 藤田亮介