Kimura Kiminori 木村公則

… Alternative Names

木村公則キムラキミノリ

KIMURA Kiminori 木村公則

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Researcher Number	70397339
Other IDs
Affiliation (Current)	2025: 地方独立行政法人東京都立病院機構東京都立駒込病院(臨床研究室), 肝臓内科, 部長 2025: 公益財団法人東京都医学総合研究所, 疾患制御研究分野, 研究員
Affiliation (based on the past Project Information) *help	2025: 地方独立行政法人東京都立病院機構東京都立駒込病院(臨床研究室), 肝臓内科, 部長 2022 – 2023: 地方独立行政法人東京都立病院機構東京都立駒込病院(臨床研究室), 肝臓内科, 部長 2016 – 2020: 東京都立駒込病院(臨床研究室), 肝臓内科, 部長 2015: 東京都立駒込病院(臨床研究室), その他部局等, その他 2012 – 2013: 公益財団法人東京都医学総合研究所, ゲノム医科学研究分野, 研究員 … More 2011: (財)東京都医学総合研究所, ゲノム医科学研究分野, 研究員 2008 – 2010: Tokyo Metropolitan Organization for Medical Research, 東京都臨床医学総合研究所, 研究員 2007 – 2008: The University of Tokyo, Department of Immunotherapeutics,, Assistant professor 2007: 東京大学, 医学部附属病院, 助教 2005 – 2006: 岐阜大学, 人獣感染防御研究センター, 助手 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 53010:Gastroenterology-related Except Principal Investigator Radiation science
Keywords	Principal Investigator 肝硬変 / PRI-724 / 線維化 / small interference RNA / HCV / B型肝炎ウイルス / MASH / PD-L1 / 治療薬 / メモリT細胞 … More / PDL1抗体 / 肝細胞癌 / 免疫療法 / IL-18 / 肝細胞がん / Wnt 阻害剤 / b-カテニン / Wntシグナル / 肝線維化 / wnt シグナル / MMP / Wnt阻害剤 / RNA technology / antiviral drug / Hepatitis B virus / ウイルス複製 / RNA工学 / マウス / 創薬 / 感染症 / 抗ウイルス薬 / siRNA / サイトカイン / 慢性肝炎 / 治療ワクチン / ワクチン / CD44 / 接着因子 / 肝障害 / ケモカイン / CTL / 免疫 / 肝臓学 … More Except Principal Investigator 骨転移 / 臨床研究 / MDSC / CTL / 放射線治療 / がん治療 / がん / γδT細胞 / 免疫細胞治療 / 免疫 / 放射線治療学 Less

Development of therapeutic agents for a liver fibrosis model using extracellular vesicles derived from hepatic progenitor cellsPrincipal Investigator
- Principal Investigator
  
  木村公則
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Metropolitan Hospital Organization Tokyo Metropolitan Komagome Hospital
肝細胞がんに対する新規免疫チェックポイント阻害剤併用療法の開発Principal Investigator
- Principal Investigator
  
  木村公則
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Metropolitan Hospital Organization Tokyo Metropolitan Komagome Hospital
Elucidation of the mechanism of liver fibrosis by Wnt-b-catenin pathwayPrincipal Investigator
- Principal Investigator
  
  Kimura Kiminori
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Tokyo Metropolitan Komagome Hospital (Clinical research laboratory)
Development of new anti-fibrotic therapeutic drug for targeting Wnt signalPrincipal Investigator
- Principal Investigator
  
  Kimura Kiminori
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Metropolitan Komagome Hospital (Clinical research laboratory)
Development of the novel therapeutic vaccine using persistent viral hepatitis infection modelPrincipal Investigator
- Principal Investigator
  
  KIMURA Kiminori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
The analysis of inflammatory cascade between antigen specific CTLs and liver injury using hepatitis modelPrincipal Investigator
- Principal Investigator
  
  KIMURA Kiminori
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Tokyo Metropolitan Organization for Medical Research
Novel combined modality therapy with radiotherapy and immunotherapy for the treatment of cancer
- Principal Investigator
  
  KAKIMI Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Radiation science
- Research Institution
  The University of Tokyo
The study of anti-hepatitis B virus drugs using RNA technologyPrincipal Investigator
- Principal Investigator
  
  KIMURA Kiminori
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  The University of Tokyo
  Gifu University

[Book] 論理的創薬入門2006
- Author(s)
  桑田一夫, 木村公則, 他
- Total Pages
  283
- Publisher
  共立出版
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Inhibition of CBP/β-catenin signaling ameliorated fibrosis in cholestatic liver disease2022
- Author(s)
  Kimura Masamichi、Nishikawa Koji、Osawa Yosuke、Imamura Jun、Yamaji Kenzaburo、Harada Kenichi、Yatsuhashi Hiroshi、Murata Kazumoto、Miura Kouichi、Tanaka Atsushi、Kanto Tatsuya、Kohara Michinori、Kamisawa Terumi、Kimura Kiminori
- Journal Title
  
  Hepatology Communications
  
  Volume: 6 Issue: 10 Pages: 2732
- DOI
  10.1002/hep4.2043
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06981, KAKENHI-PROJECT-22K07991, KAKENHI-PROJECT-22K08091, KAKENHI-PROJECT-19K07115
[Journal Article] Programmed cell death ligand 1 (PD-L1) blockade attenuates metastatic colon cancer growth in cAMP-response element-binding protein (CREB)-binding protein (CBP)/β-catenin inhibitor-treated livers2019
- Author(s)
  Yosuke Osawa, Ekumi Kojika, Koji Nishikawa, Masamichi Kimura, Shigenori Osakaya, Hiromi Miyauchi, Tatsuya Kanto, Yutaka Kawakami, Kiminori Kimura
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 32 Pages: 3013-3026
- DOI
  10.18632/oncotarget.26892
- Data Source
  KAKENHI-PROJECT-18K08021
[Journal Article] Long-awaited treatment for hepatitis C virus decompensated cirrhosis2019
- Author(s)
  Kimura Kiminori
- Journal Title
  
  Journal of Gastroenterology
  
  Volume: 54 Issue: 3 Pages: 299-300
- DOI
  10.1007/s00535-018-01538-6
- Data Source
  KAKENHI-PROJECT-18K08021
[Journal Article] Tumor Necrosis Factor-a-Mediated Hepatocyte Apoptosis Stimulates Fibrosis in the Steatotic Liver in Mice2018
- Author(s)
  Yosuke Osawa,1,2 Ekumi Kojika,1 Yukiko Hayashi,1 Masamichi Kimura,1 Koji Nishikawa,1 Sachiyo Yoshio,2 Hiroyoshi Doi,2 Tatsuya Kanto,2 and Kiminori Kimura1
- Journal Title
  
  HEPATOLOGY COMMUNICATIONS
  
  Volume: 2 Issue: 4 Pages: 407-420
- DOI
  10.1002/hep4.1158
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09037, KAKENHI-PROJECT-18K08021, KAKENHI-PROJECT-18K15768
[Journal Article] Reduced therapeutic effect of antiviral drugs in patients with hepatitis B virus reactivation after hematopoietic stem cell transplantation2018
- Author(s)
  Kimura Masamichi、Nishikawa Koji、Sakamaki Hisashi、Mizokami Masashi、Kimura Kiminori
- Journal Title
  
  Hepatology Research
  
  Volume: 48 Issue: 6 Pages: 469-478
- DOI
  10.1111/hepr.13044
- Data Source
  KAKENHI-PROJECT-18K08021
[Journal Article] Image analysis of the nuclear characteristics of emerin protein and the correlation with nuclear grooves and intranuclear cytoplasmic inclusions in lung adenocarcinoma2018
- Author(s)
  Kobayashi Sayaka、Saio Masanao、Fukuda Toshio、Kimura Kiminori、Hirato Junko、Oyama Tetsunari
- Journal Title
  
  Oncology Reports
  
  Volume: 41 Pages: 133-142
- DOI
  10.3892/or.2018.6848
- Data Source
  KAKENHI-PROJECT-18K08021
[Journal Article] Wnt/β-Catenin Signaling as a Potential Target for the Treatment of Liver Cirrhosis Using Antifibrotic Drugs2018
- Author(s)
  Nishikawa Koji、Osawa Yosuke、Kimura Kiminori
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 19 Issue: 10 Pages: 3103-3103
- DOI
  10.3390/ijms19103103
- Data Source
  KAKENHI-PROJECT-18K08021
[Journal Article] Safety, Tolerability, and Preliminary Efficacy of the Anti-Fibrotic Small Molecule PRI-724, a CBP/β-Catenin Inhibitor, in Patients with Hepatitis C Virus-related Cirrhosis: A Single-Center, Open-Label, Dose Escalation Phase 1 Trial.2017
- Author(s)
  2.Kimura K, Ikoma A, Shibakawa M, Shimoda S, Harada K, Saio M, Imamura J, Osawa Y, Kimura M, Nishikawa K, Okusaka T, Morita S, Inoue K, Kanto T, Todaka K, Nakanishi Y, Kohara M, Mizokami M.
- Journal Title
  
  EBioMedicine
  
  Volume: 23 Pages: 79-87
- DOI
  10.1016/j.ebiom.2017.08.016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09037, KAKENHI-PROJECT-15K15146
[Journal Article] Serum DHCR24 Auto-antibody as a new Biomarker for Progression of Hepatitis C.2015
- Author(s)
  Ezzikouri S, Kimura K, Sunagozaka H, Kaneko S, Inoue K, Nishimura T, Hishima T, Kohara M, Tsukiyama-Kohara K.
- Journal Title
  
  EBioMedicine
  
  Volume: Apr 13;2(6) Issue: 6 Pages: 604-12
- DOI
  10.1016/j.ebiom.2015.04.007
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09037, KAKENHI-PROJECT-15K15146, KAKENHI-PROJECT-26253046, KAKENHI-PROJECT-24390117
[Journal Article] M2 macrophages play critical roles in progression of inflammatory liver disease in hepatitis C virus transgenic mice.2015
- Author(s)
  1.Ohtsuki T, Kimura K, Tokunaga Y, Tsukiyama-Kohara K, Tateno C, Hayashi Y, Hishima T, Kohara M
- Journal Title
  
  J Virol
  
  Volume: Oct 14;90(1) Issue: 1 Pages: 300-7
- DOI
  10.1128/jvi.02293-15
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K09037, KAKENHI-PROJECT-15K15146, KAKENHI-PROJECT-26860312, KAKENHI-PUBLICLY-15H01272, KAKENHI-PROJECT-15H04739, KAKENHI-PROJECT-24390117
[Journal Article] Inhibition of Cyclic Adenosine Monophosphate (cAMP)-response Element-binding Protein (CREB)- binding Protein (CBP)/β-Catenin Reduces Liver Fibrosis in Mice.2015
- Author(s)
  Osawa Y, Oboki K, Imamura J, Kojika E, Hayashi Y, Hishima T, Saibara T, Shibasaki F, Kohara M, Kimura K
- Journal Title
  
  EBioMedicine
  
  Volume: 2 Issue: 11 Pages: 1751-8
- DOI
  10.1016/j.ebiom.2015.10.010
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K09010, KAKENHI-PROJECT-15K09037, KAKENHI-PROJECT-26460965
[Journal Article] Should we try antiviral therapy for hepatitis C virus infection with pyoderma gangrenosum-like lesions?2014
- Author(s)
  Kiminori Kimura
- Journal Title
  
  Hepatology research
  
  Volume: 44 Issue: 2 Pages: 173-175
- DOI
  10.1111/hepr.12158
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] Should we try anti-viral therapy for hepatitis C virus infection with pyoderma gangrenosum-like lesions?2013
- Author(s)
  Kimura k
- Journal Title
  
  Hepatology Research
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] The development of therapeutic vaccine for hepatitis C virus2012
- Author(s)
  Kimura k, kohara m
- Journal Title
  
  Gan To Kagaku Ryoho
  
  Volume: 39(10) Pages: 1451-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] Kinetics of peripheral hepatitis B virus-specific CD8(+) T cells in patients with onset of viral reactivation.2012
- Author(s)
  Aoki J, Kowazaki Y, Ohtsuki T, Okamoto R, Ohashi K, Hayashi S, Sakamaki H, Kohara M, Kimura K
- Journal Title
  
  J Gastroenterol
  
  Volume: 47 Issue: 6 Pages: 22-22
- DOI
  10.1007/s00535-012-0676-y
- NAID
  10031184063
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-25114712, KAKENHI-PROJECT-25860305
[Journal Article] Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver2012
- Author(s)
  Sekiguchi S, Kimura K, Chiyo T, Ohtsuki T, Tobita Y, Tokunaga Y, Yasui F, Tsukiyama-Kohara K, Wakita T, Tanaka T, Miyasaka M, Mizuno K, Hayashi Y, Hishima T, Matsushima K, Kohara M.
- Journal Title
  
  PLoS One
  
  Volume: 7(12)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] The development of therapeutic vaccine for hepatitis C virus2012
- Author(s)
  Kimura K, Kohara M. Gan To Kagaku Ryoho.
- Journal Title
  
  Review
  
  Volume: Oct;39(10) Pages: 1451-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] Immunization with a recombinant vaccinia virus that encodes nonstructural proteins of the hepatitis C virus suppresses viral protein levels in mouse liver.2012
- Author(s)
  Sekiguchi, S, Kimura K, Chiyo T, Ohtsuki T, Tobita Y, Tokunaga Y, Yasui F, Tsukiyama-Kohara K, Wakita T, Tanaka T, Miyasaka M, Mizuno K, Hayashi Y, Hishima T, Matsushima K and Kohara M.
- Journal Title
  
  PLoS One
  
  Volume: 7 Issue: 12 Pages: e51656-e51656
- DOI
  10.1371/journal.pone.0051656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590547, KAKENHI-PROJECT-23591004, KAKENHI-PROJECT-23659238, KAKENHI-PROJECT-24390117, KAKENHI-PUBLICLY-23114511
[Journal Article] An experimental mouse model for hepatitis C virus.2011
- Author(s)
  Kimura K, Kohara M.
- Journal Title
  
  Exp.Animal.
  
  Volume: 60(2) Pages: 93-100
- NAID
  10029550066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Role of interleukin-18 in intrahepatic inflammatory cells recruitment in acute liver injury.2011
- Author(s)
  Kimura K, Sekiguchi S, Hayashi S, Hayashi y, Hishima T, Nagaki M, Kohara M.
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 89(3) Pages: 433-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] Role of interleukin-18 in intrahepatic inflammatory cells recruitment in acute liver injury.2011
- Author(s)
  Kimura K, Sekiguchi S, Hayashi S, Hayashi y, Hishima T, Nagaki M, Kohara M
- Journal Title
  
  Journal of Leukocyte Biology 89(3)
  
  Pages: 433-42
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] An experimental mouse model for hepatitis C virus.2011
- Author(s)
  Kimura K, Kohara M
- Journal Title
  
  Exp.Animal. 60(2)
  
  Pages: 93-100
- NAID
  10029550066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Role of interleukin-18 in intrahepatic inflammatory cell recruitment in acute liver injury2011
- Author(s)
  Kimura K, Sekiguchi S, Hayashi S, Hayashi Y, Hishima T, Nagaki M, Kohara M.
- Journal Title
  
  J Leukoc Biol
  
  Volume: Mar;89(3) Issue: 3 Pages: 433-42
- DOI
  10.1189/jlb.0710412
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] An experimental mouse model for hepatitis C virus.2011
- Author(s)
  Kimura K and Kohara M
- Journal Title
  
  Exp. Animal.
  
  Volume: 60(2) Pages: 93-100
- NAID
  10029550066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] An experimental mouse model for hepatitis C virus2011
- Author(s)
  Kimura K, Kohara M.
- Journal Title
  
  Exp Anim
  
  Volume: 60(2) Pages: 93-100
- NAID
  10029550066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591004
[Journal Article] Is there a delayed gastric emptying of patients with early-stage, untreated Parkinson's disease? An analysis using the 13C-acetate breath test.2011
- Author(s)
  Tanaka Y, Kato T, Nishida H, Yamada M, Koumura A, Sakurai T, Hayashi Y, Kimura A, Hozumi I, Araki H, Murase M, Nagaki M, Moriwaki H, Inuzuka T
- Journal Title
  
  J Neurol. 258(3)
  
  Pages: 421-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Roles of CD44 in chemical-induced liver injury.2010
- Author(s)
  Kimura K, Hayashi S, Nagaki M
- Journal Title
  
  Curr Opin Drug Discov Devel. 13(1)(Review)
  
  Pages: 96-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Roles of CD44 in chemical-induced liver injury2010
- Author(s)
  Kimura, et al.
- Journal Title
  
  Current Opinion in Drug Discovery & Development 13(1)
  
  Pages: 96-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Role of interleukin-18 in intrahepatic inflammatory cells recruitment in acute liver injury.2010
- Author(s)
  Kimura k, Sekiguchi S, et al.
- Journal Title
  
  Journal of Leukocyte Biology
  
  Volume: 89(3) Pages: 433-442
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] No relapse of neuromyelitis optica during secondary low B lymphocytes.2010
- Author(s)
  Tanaka S, Kimura K, Kawachi t, Inuzuka T
- Journal Title
  
  Neurology 75(19)
  
  Pages: 1745-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] No relapse of neuromyelitis optica during secondary low B lymphocytes.2010
- Author(s)
  Tanaka S, Kimura K, et al.
- Journal Title
  
  Neurology
  
  Volume: 75(19) Pages: 1745-1747
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Extended treatment duration of peginterferon-alpha2b plus ribavirin for 72 and 96 weeks in hepatitis C genotype 1-infected late responders.2009
- Author(s)
  Nagaki M, Shimizu M, Sugihara JI, Tomita E, Sano C, Naiki T, Kimura K, Amano K, Sakai T, Ninomiya M, Kojima T, Katsumura N, Fujimoto M, Moriwaki H
- Journal Title
  
  Aliment Pharmacol Ther. 30(4)
  
  Pages: 343-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Effect of CD44 blocking for CTL-induced acute liver injury in the hepatitis B virus transgenic mice.2009
- Author(s)
  Kimura K, Nagaki M, Saio M, Moriwaki M, Kakimi K
- Journal Title
  
  J gastroenterology 44(3)
  
  Pages: 218-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Pathological role of CD44 on NKT cells in carbon tetrachloride-mediated liver injury2009
- Author(s)
  Kimura, et al.
- Journal Title
  
  Hepatol Res 39(1)
  
  Pages: 93-105
- NAID
  10025324211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Pathological role of CD44 on NKT cells in carbon tetrachloride-mediated liver injury2009
- Author(s)
  Kimura k, et al.
- Journal Title
  
  Hepatology Research 39(1)
  
  Pages: 93-105
- NAID
  10025324211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Pathological role of CD44 on NKT cells in carbon tetrachloride-mediated liver injury.2009
- Author(s)
  Kimura K, Nagaki M, Matsura T, Moriwaki H, Kakimi K
- Journal Title
  
  Hepatol Res 39(1)
  
  Pages: 93-105
- NAID
  10025324211
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Effect of CD44 blocking for CTL-induced acute liver injury in the hepatitis B virus transge2009
- Author(s)
  Kimura k, et al.
- Journal Title
  
  Journal of gastroenterology 44(3)
  
  Pages: 218-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Effect of CD44 blocking for CTL-induced acute liver injury in the hepatitis B virus transgenic mice2009
- Author(s)
  Kimura, et al.
- Journal Title
  
  J gastroenterology 44(3)
  
  Pages: 218-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Critical role of CD44 in hepatotoxin-mediated liver injury2008
- Author(s)
  Kimura K
- Journal Title
  
  J Hepatol Epub(掲載確定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19390314
[Journal Article] Critical role of CD44 in Hepatotoxin mediated liver injury2008
- Author(s)
  Kimura K, Nagaki M, Kakimi K, Saio M, Saeki T, Okuda Y, Kuwata K, Moriwaki H
- Journal Title
  
  J hepatol 48(6)
  
  Pages: 952-61
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Memory Thl cell augments tumor-specific CTL following transcutaneous peptide immuniza2008
- Author(s)
  Hosoi A, Takeda Y, Furuichi Y, Kimura K
- Journal Title
  
  Cancer Research
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Critical role of CD44 in Hepatotoxin-mediated liver injury2008
- Author(s)
  Kimura K, Nagaki M, Kakimi K, Saio M, e
- Journal Title
  
  Journal of Hepatology
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination.2008
- Author(s)
  Hosoi A, Takeda Y, Sakuta K, Ueha S, Kurachi M, Kimura K, Maekawa R, Kakimi K
- Journal Title
  
  Biochem Biophys Res Commun. 371(2)
  
  Pages: 242-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Dendritic cell vaccine with mRNA targeted to the proteasome by polyubiquitination.2008
- Author(s)
  Hosoi A, Takeda Y, Sakuta K, Ueha S, Kurachi M, Kimura K, Maekawa R, Kakimi K.
- Journal Title
  
  Biochem Biophys Res Commun 371
  
  Pages: 242-246
- Data Source
  KAKENHI-PROJECT-19390314
[Journal Article] Memory Th1 cells augment tumor-specific CTL following transcutaneous peptide immunization.2008
- Author(s)
  Hosoi A, Takeda Y, Furuichi Y, Kurachi M, Kimura K, Maekawa R, Takatsu K, Kakimi K.
- Journal Title
  
  Cancer Res 68
  
  Pages: 3941-3949
- Data Source
  KAKENHI-PROJECT-19390314
[Journal Article] Critical role of CD44 in hepatotoxin-mediated liver injury2008
- Author(s)
  Kimura K, et al.
- Journal Title
  
  Journal of Heputology Jun;48(6)
  
  Pages: 952-961
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Memory Th1 cell augments tumor-specific CTL following transcutaneous peptide immunization.2008
- Author(s)
  Hosoi A, Takeda Y, Furuichi Y, Kurachi M, Kimura K, Maekawa R, Takatsu K, Kakimi K
- Journal Title
  
  Cancer Res. 68(10)
  
  Pages: 3941-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Critical role of CD44 in Hepatotoxin-mediated liver injury2008
- Author(s)
  Kimura K, Nagaki M, Kakimi K, Saio M, Saeki T, Okuda Y, Kuwata K, Moriwaki H.
- Journal Title
  
  J hepatol
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Memory Th1 cell augments tumor-specific CTL following transcutaneous peptide immunization.2008
- Author(s)
  Hosoi A, Takeda Y, Furuichi Y, Kimura K, et. al.
- Journal Title
  
  Cancer research
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Critical role of CD44 in Hepatotoxin-mediated liver injury2008
- Author(s)
  Kimura K, Nagaki M, KakimiK, Saio M, et. al.
- Journal Title
  
  Journal of Hepatology
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Inhibition of nuclear factor-kappa B exacerbates severe liver injury in Hepatitis B virus transgenic mice model2007
- Author(s)
  Satake S, Nagaki M, Kimura k, et al.
- Journal Title
  
  Hepatology Research (in press)
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Intrinsic resistance to TNF-α-induced hepatocyte apoptosis in ICR mice; The role of a short form of cellular FLICE-like inhibitory protein2007
- Author(s)
  Takai S, Nagaki m, Kimura K, wt al.
- Journal Title
  
  Laboratory Investigation (in press)
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-lbe2007
- Author(s)
  Ogiso T, Nagaki M, Kimura K, et. al.
- Journal Title
  
  Journal of Hepatology 47(6)
  
  Pages: 816-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Hot spots in prion protein for pathogenic conversion.2007
- Author(s)
  Kuwata K, Nishida N, Matsumoto T, Kamatari YO, Kimura K, et. al.
- Journal Title
  
  Proc Natl Acad Sci U S A. 104(29)
  
  Pages: 11921-6
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-lbeta.2007
- Author(s)
  Ogiso T, Nagaki M, Kimura K, et. al.
- Journal Title
  
  Journal of Hepatology 47(6)
  
  Pages: 816-5
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Intrinsic resistance to TNF-alpha-induced hepatocyte apoptosis in ICR mice correlates with expression of a short form of c-FLIP2007
- Author(s)
  Takai S, Nagaki M, Imao M, Kimura K, Kozawa O, Moriwaki H.
- Journal Title
  
  Lab Invest 87(6)
  
  Pages: 572-81
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Significant effect of hepatitis C virus specific CTLs on viral clearance in patients with type C chronic hepatitis treated with antiviral agents2007
- Author(s)
  Satake S, Nagaki M, Kimura K, et. al.
- Journal Title
  
  Hepatology Research
- NAID
  10024148453
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] B型肝炎に対する自然免疫の抗ウイルス効果2007
- Author(s)
  木村公則、永木正仁、森脇久隆
- Journal Title
  
  消化器科
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Hot spots in prion protein for pathogenic conversion2007
- Author(s)
  Kuwata K, Nishida N, Matsumoto T, Kamatari YO, Hosokawa-Muto J, Kodama K, Nakamura HK, Kimura K, Kawasaki M, Takakura Y, Shirabe S, Takata J, Kataoka Y, Katamine S.
- Journal Title
  
  Proc Natl Acad Sci USA 104
  
  Pages: 11921-6
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Significant effect of hepatitis C virus specific CTLs on viral clearance in patients with type C chronic hepatitis treated with antiviral agents.2007
- Author(s)
  Satake S, Nagaki M, Kimura K, Naiki T, Hayashi H, Sugihara J, Tomita E, Moriwaki H
- Journal Title
  
  Hepatol Res.
- NAID
  10024148453
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390203
[Journal Article] Inhibition of nuclear factor-kappa B induces inflammatory cell migration and exacerbates severe liver injury in hepatitis B virus transgenic mice2007
- Author(s)
  Satake S, Nagaki M, Kimura K, Moriwaki H.
- Journal Title
  
  Hepatol Res 37(7)
  
  Pages: 524-30
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Granulocyte colony-stimulating factor impairs liver regeneration in mice through the up-regulation of interleukin-1beta2007
- Author(s)
  Ogiso T, Nagaki M, Takai S, Tsukada Y, Mukai T, Kimura K, Moriwaki H.
- Journal Title
  
  J Hepatol 47(6)
  
  Pages: 816-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Inhibition of nuclear factor-kappa B induces inflammatory cell migration and exacerbates severe liver injury in hepatitis B virus transgenic mice.2007
- Author(s)
  Satake S, Nagaki M, Kimura K, Moriwaki H.
- Journal Title
  
  Hepatology Research 37(7)
  
  Pages: 524-30
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Significant effect of hepatitis C virus specific CTLs on viral clearance in patients with type C chronic hepatitis treated with antiviral agents2007
- Author(s)
  Satake S, Nagaki M, Kimura K, Naiki T, Hayashi H, Sugihara J, Tomita E, Moriwaki H.
- Journal Title
  
  Hepatol Res
- NAID
  10024148453
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Role of macrophage migration inhibitory factor in hapatitis B virus-specific cytotoxic-T-lymphocyte-induced liver injury.2006
- Author(s)
  Kiminori Kimura
- Journal Title
  
  Clinical and Vaccine Immunology 13
  
  Pages: 415-419
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Prevention of hepatic fibrosis in nonobese diabetic mice : a critical role for interferon-γ2006
- Author(s)
  Mukai T, Nagaki M, Kimura K, et al.
- Journal Title
  
  Liver International 26
  
  Pages: 1006-1006
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease2006
- Author(s)
  Kimura K, Moriwaki H, Nagaki M, Saio M, Nakamoto Y, Naito M, Kuwata K, Chisari FV.
- Journal Title
  
  Am J Pathol 168(3)
  
  Pages: 786-95
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Pathogenic role of B cells in anti-CD40-induced necroinflammatory liver disease.2006
- Author(s)
  Kiminori Kimura
- Journal Title
  
  The American Journal of Pathology 168
  
  Pages: 786-795
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Prevention of hepatic fibrosis in nonobese diabetic mice : a critical role for interferon-gamma2006
- Author(s)
  Mukai T, Nagaki M, Imose M, Kimura K, Satake S, Takai S, Moriwaki H.
- Journal Title
  
  Liver Int 26(8)
  
  Pages: 1006-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Role of macrophage migration inhibitory factor in hepatitis B virus-specific cytotoxic-T-lymphocyte-induced liver injury2006
- Author(s)
  Kimura K, Nagaki M, Nishihira J, Satake S, Kuwata K, Moriwaki H.
- Journal Title
  
  Clin Vaccine Immunol 13(3)
  
  Pages: 415-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Blockade of neutrophil elastase attenuates severe liver injury in hepatitis B transgenic mice2005
- Author(s)
  Takai S, Kimura K, Nagaki M, Satake S, Kakimi K, Moriwaki H.
- Journal Title
  
  J Virol 79(24)
  
  Pages: 15142-50
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Journal Article] Normal liver regeneration and liver cell apoptosis after partial hepatectomy in tumor necrosis factor-alpha-deficient mice2005
- Author(s)
  Hayashi H, Nagaki M, Imose M, Osawa Y, Kimura K, Takai S, Imao M, Naiki T, Kato T, Moriwaki H.
- Journal Title
  
  Liver Int 25(1)
  
  Pages: 162-70
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Patent] がんの治療剤2022
- Inventor(s)
  木村公則
- Industrial Property Rights Holder
  木村公則
- Industrial Property Rights Type
  特許
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-22K08091
[Presentation] Early memory T細胞を標的とした肝細胞がんに対する新規治療法の開発2023
- Author(s)
  木村公則
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-22K08091
[Presentation] Tissue macrophages are responsible for inflammatory liver disease in the hepatitis C virus transgenic mice2013
- Author(s)
  Kiminori Kimura, Takahiro Otsuki, Yuko Tokunaga, Michinori Kohara
- Organizer
  アメリカ肝臓学会
- Place of Presentation
  ワシントン、USA
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] Ki netics of peripheral hepatitis B virus-specific C D8+ T cells in patients with onset of viral rea ctivation. Poster presentation2013
- Author(s)
  Kimura K, Aoki J, Kowazaki Y, et al.
- Organizer
  AASLD (Americ an Association for the study of Liver Disease s) Single topic Conference
- Place of Presentation
  Washington DC
- Year and Date
  2013-03-21
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] KINETICS OF PERIPHERAL HEPATITIS B VIRUS-SPECIFIC CD8+ T CELLS IN PATIENTS WITH ONSET OF VIRAL REACTIVATION2013
- Author(s)
  Kimura k, Aoki J, Kohara m
- Organizer
  AASLD
- Place of Presentation
  ワシントン
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] The efficac y of entecavir in patients with hepatitis B viru s reactivation after allo-HSCT2013
- Author(s)
  Yoshioka K, Kimura K, et al.
- Organizer
  第75回日本血液学会学術集会、Poster presentation PS-1 -374
- Place of Presentation
  札幌
- Year and Date
  2013-11-09
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] 造血幹細胞移植後のHBV再活性化における宿主の免疫応答の解析2013
- Author(s)
  木村公則、坂巻壽他
- Organizer
  第17回日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2013-10-09
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] Kinetics of Peripheral Hepatitis B Virus-specific CD8+ T Cells in Patients with Onset of Viral Reactivation2012
- Author(s)
  Kimura k, Aoki J, Kohara m
- Organizer
  AASLD
- Place of Presentation
  ボストン
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] C型慢性肝炎に対する治療ワクチンの有効性について2012
- Author(s)
  木村公則、小原道法
- Organizer
  日本肝臓学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] HBV再活性化時における宿主免疫動態の解析2012
- Author(s)
  木村公則、青木淳、林星舟
- Organizer
  日本肝臓学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] Immunization with a recombinant vaccinia virus encoding a nonstructural protein of the hepatitis C virus ameliorates chronic hepatitis in the liver of transgenic mice2012
- Author(s)
  Kimura k, Kohara m
- Organizer
  keystone symposium "Immunological Mechanisms of Vaccination
- Place of Presentation
  カナダ
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] HCV感染による慢性肝炎の病態形成と炎症性サイトカインの関与2011
- Author(s)
  木村公則、小原道法
- Organizer
  日本肝臓学会総会シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2011
- Author(s)
  Kiminori Kimura
- Organizer
  keystone symposia
- Place of Presentation
  Calgary(CANADA)
- Year and Date
  2011-02-01
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2011
- Author(s)
  Kiminori Kimura, Michinori Kohara, et al
- Organizer
  keystone symposia
- Place of Presentation
  Calgary
- Year and Date
  2011-02-01
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2010
- Author(s)
  Kiminori Kimura
- Organizer
  AASLD
- Place of Presentation
  Boston(USA)
- Year and Date
  2010-12-02
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2010
- Author(s)
  Kiminori Kimura, Michinori Kohara, et al
- Organizer
  HCV meeting
- Place of Presentation
  Yokohama
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2010
- Author(s)
  Kiminori Kimura, Michinori Kohara, et al
- Organizer
  AASLD
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] C型慢性肝炎に対する遺伝子組換えワクチニアウイルスによる新たな治療戦略2010
- Author(s)
  木村公則、小原道法
- Organizer
  日本肝臓学会大会ワークショップ
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2010
- Author(s)
  Kiminori Kimura
- Organizer
  EASL topic conference
- Place of Presentation
  Amsterdam(オランダ)
- Year and Date
  2010-02-18
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Critical role of IL-18 for intrahepatic inflammatory cell recruitment in activated macrophages mediated liver injury2010
- Author(s)
  Kiminori Kimura
- Organizer
  AASLD
- Place of Presentation
  Boston(USA)
- Year and Date
  2010-12-01
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Critical role of IL-18 for intrahepatic inflammatory cell recruitment in activated macrophages mediated liver injury2010
- Author(s)
  Kiminori Kimura, Satoshi Sekiguchi, et al
- Organizer
  AASLD
- Place of Presentation
  Boston
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Hepatitis C virus-mediated pathogenesis is dependent on inflammatory cytokines irrespective of the HCV protein level2010
- Author(s)
  Kiminori Kimura
- Organizer
  HCV meeting
- Place of Presentation
  Yokohama(JAPAN)
- Year and Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Role of CD44 in chemical induced liver injury2010
- Author(s)
  Kiminori Kimura, Masahito Nagaki
- Organizer
  EASL topic conference
- Place of Presentation
  Amsterdam
- Year and Date
  2010-02-18
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] 抗CD40抗体を用いた肝障害モデルにおけるNKT細胞とマクロファージの相互作用2009
- Author(s)
  木村公則
- Organizer
  第45回日本肝臓学会総会
- Place of Presentation
  兵庫県・神戸ポートピアホテル、神戸国際展示場
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Critical role of CD44 in Hepatotoxin mediated liver injury2008
- Author(s)
  Kiminori Kimura, Masahito nagaki, Kazuhiro Kakimi, Hisataka Moriwaki
- Organizer
  AASLD
- Place of Presentation
  Boston, USA
- Year and Date
  2008-11-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Presentation] B型急性肝炎モデルにおける Thioredoxin-1 の関与2008
- Author(s)
  木村公則
- Organizer
  日本肝臓学会東部会
- Place of Presentation
  東京
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] ゾレドロン酸を用いて培養したVγ9Vδ2T 細胞による免疫細胞治療2008
- Author(s)
  大宮、近藤真、作田和子、野口敦崇、有吉直子、佐藤和聡、佐藤志保、佐藤啓介、細井亮宏、中野由貴子、木村公則、垣見和宏
- Organizer
  第12回基盤的癌免疫研究会総会
- Data Source
  KAKENHI-PROJECT-19390314
[Presentation] B型肝炎トランスジェニックマウスを用いた急性肝炎モデルにおけるCTLとCD44の相互作用2008
- Author(s)
  木村公則
- Organizer
  日本肝臓学会総会
- Place of Presentation
  松山市
- Year and Date
  2008-06-06
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] B型急性肝炎モデルにおけるThioredoxin-1の関与2008
- Author(s)
  木村公則、永木正仁
- Organizer
  日本肝臓学会東部会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-12-04
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] B型肝炎治療における自然免疫制御の有用性2008
- Author(s)
  木村公則、永木正仁
- Organizer
  日本肝臓学会シンポジウム
- Place of Presentation
  東京
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Interaction of CTLs and CD44 in acute hepatitis model using hepatitis B virus transgenic mice2008
- Author(s)
  Kiminori Kimura, Michinori Kohara, et al
- Organizer
  AASLD
- Place of Presentation
  San Francisco
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] B型肝炎治療における自然免疫制御の有用性2008
- Author(s)
  木村公則
- Organizer
  日本肝臓学会大会
- Place of Presentation
  東京
- Year and Date
  2008-10-02
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Interaction of CTLs and CD44 in acute hepatitis model using hepatitis B virus transgenic m2008
- Author(s)
  Kiminori Kimura
- Organizer
  The annual meeting of the american association for the study of liver diseas
- Place of Presentation
  サンフランシスコ
- Year and Date
  2008-11-02
- Data Source
  KAKENHI-PROJECT-20390203
[Presentation] Critical role of CD44 in Hepatotoxin-mediated liver injury2007
- Author(s)
  Kiminori Kimura, Kazuhiro Kakimi
- Organizer
  AASLD
- Place of Presentation
  Boston
- Year and Date
  2007-03-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Presentation] ユビキチン配列を付加したmRNA を導入した樹状細胞によるCTL の誘導2007
- Author(s)
  竹田やよい、細井亮宏、前川隆司、木村公則、垣見和宏
- Organizer
  第11回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390314
[Presentation] 四塩化炭素を用いた肝障害モデルにおけるCD44の役割2007
- Author(s)
  木村公則、永木正仁、垣見和宏、森脇久隆
- Organizer
  日本肝臓学会
- Place of Presentation
  大阪
- Year and Date
  2007-03-06
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Presentation] Critical role of CD44 in Hepatotoxin-mediated liver injury2007
- Author(s)
  木村公則、垣見和宏
- Organizer
  日本免疫学会
- Place of Presentation
  横浜
- Year and Date
  2007-12-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Presentation] TLR7 リガンドとTh エピトープペプチドを用いた経皮ペプチド免疫による腫瘍特異的CTLの誘導2007
- Author(s)
  細井亮宏、竹田やよい、前川隆司、木村公則、高津聖志、垣見和
- Organizer
  第11回基盤的癌免疫研究会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-19390314
[Presentation] Crucial role of CD44 in liver injury2007
- Author(s)
  kiminori kimura, Masahito nagaki, Kazuhiro Kakimi, Toshinori Nakayama, Masaru Taniguchi and Hisataka Moriwaki
- Organizer
  AAI
- Place of Presentation
  San Diego, USA
- Year and Date
  2007-04-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17590628
[Presentation] HCV持続発現マウスを用いたHCVワクチンの開発
- Author(s)
  木村公則、小原道法
- Organizer
  日本肝臓学会大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] C型慢性肝炎に対するＨＣＶ遺伝子組換えワクチニアウイルスによる治療効果
- Author(s)
  木村公則、小原道法
- Organizer
  日本免疫学会学術総会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] ＨＣＶ感染による慢性肝炎の病態形成と炎症性サイトカインの関与
- Author(s)
  木村公則、小原道法
- Organizer
  日本肝臓学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] C型肝炎発症におけるウイルス蛋白質と炎症性サイトカイン
- Author(s)
  木村公則、小原道法
- Organizer
  日本癌学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23591004
[Presentation] Recombinant vaccinia virus encoding hepatitis C virus nonstructural protein modulates host immune response and ameliorates chronic hepatitis in mouse model
- Author(s)
  Kiminori Kimura, Michinori Kohara
- Organizer
  AASLD
- Place of Presentation
  サンフランシスコ
- Data Source
  KAKENHI-PROJECT-23591004

1. NAGAKI Masahito (30293559)

# of Collaborated Projects: 3 results

# of Collaborated Products: 36 results
2. UEHA Satoshi (00447385)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
3. KAKIMI Kazuhiro (80273358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
4. KURACHI Makoto (00396722)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
5. IGAKI Hiroshi (90361344)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. SHIRAISHI Kenshiro (40447404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. TAGO Masao (50282520)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. FURUICHI Yoshihiro (70384998)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. SAIO Masanao (40242721)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MATSUSHIMA Kouji (50222427)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. MIYAGISHI Makoto (30323538)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MORIWAKI Hisataka (50174470)

# of Collaborated Projects: 1 results

# of Collaborated Products: 15 results
13. KOHARA Michinori (10250218)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
14. 大澤陽介 (60447787)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 齊尾征直

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
16. 小原恭子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 西原利治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kimura Kiminori 木村 公則

木村 公則 キムラ キミノリ

KIMURA Kiminori 木村 公則

Research Projects

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Co-Researchers

Development of therapeutic agents for a liver fibrosis model using extracellular vesicles derived from hepatic progenitor cellsPrincipal Investigator

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肝細胞がんに対する新規免疫チェックポイント阻害剤併用療法の開発Principal Investigator

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Elucidation of the mechanism of liver fibrosis by Wnt-b-catenin pathwayPrincipal Investigator

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Development of new anti-fibrotic therapeutic drug for targeting Wnt signalPrincipal Investigator

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Development of the novel therapeutic vaccine using persistent viral hepatitis infection modelPrincipal Investigator

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The analysis of inflammatory cascade between antigen specific CTLs and liver injury using hepatitis modelPrincipal Investigator

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Novel combined modality therapy with radiotherapy and immunotherapy for the treatment of cancer

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The study of anti-hepatitis B virus drugs using RNA technologyPrincipal Investigator

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[Book] 論理的創薬入門2006

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[Journal Article] Inhibition of CBP/β-catenin signaling ameliorated fibrosis in cholestatic liver disease2022

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[Journal Article] Programmed cell death ligand 1 (PD-L1) blockade attenuates metastatic colon cancer growth in cAMP-response element-binding protein (CREB)-binding protein (CBP)/&#x3B2;-catenin inhibitor-treated livers2019

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[Journal Article] Long-awaited treatment for hepatitis C virus decompensated cirrhosis2019

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[Journal Article] Tumor Necrosis Factor-a-Mediated Hepatocyte Apoptosis Stimulates Fibrosis in the Steatotic Liver in Mice2018

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[Journal Article] Reduced therapeutic effect of antiviral drugs in patients with hepatitis B virus reactivation after hematopoietic stem cell transplantation2018

Kimura Kiminori 木村公則

木村公則キムラキミノリ

KIMURA Kiminori 木村公則

[Journal Article] Programmed cell death ligand 1 (PD-L1) blockade attenuates metastatic colon cancer growth in cAMP-response element-binding protein (CREB)-binding protein (CBP)/β-catenin inhibitor-treated livers2019