Yamaguchi Shigeru 山口秀

… Alternative Names

YAMAGUCHI Shigeru 山口秀

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Researcher Number	70399939
Other IDs
Affiliation (Current)	2025: 北海道大学, 医学研究院, 講師
Affiliation (based on the past Project Information) *help	2021 – 2024: 北海道大学, 医学研究院, 講師 2019 – 2021: 北海道大学, 大学病院, 講師 2017: 北海道大学, 大学病院, 助教 2016: 北海道大学, 医学研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator 神経膠腫 / 膠芽腫 / G6PC3 / hypoxia / glioblastoma / photodynamic diagnosis / PpIX / IDH / lower-grade glioma / photodyanamic dianogisis … More / lower-grade gliomas / PEPT2 / 5-ALA / 蛍光診断 / 脳神経疾患 / マイクロRNA / メチオニン / 包括的遺伝子解析 / グリオーマ / gene expression analysis … More Except Principal Investigator PD-1 / EZH2 / ATRT / 神経鞘腫 / 疾患特異的iPS細胞 / neurofibromatosis type 2 / Schwann細胞 / 人工多能性幹細胞 / iPS細胞 / NF2 / 神経線維腫症2型 Less

Analysis of treatment effect of combination with EZH2 inhibitor and immune checkpoint inhibitor for aypical rhabdoid / teratoid tumors
- Principal Investigator
  
  金子貞洋
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Hokkaido University
膠芽腫における低酸素内糖代謝亢進メカニズムの検証Principal Investigator
- Principal Investigator
  
  山口秀
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Photodynamic diagnosis for low-grade gliomas: functional analysis of porphyrin synthesis pathwayPrincipal Investigator
- Principal Investigator
  
  Yamaguchi Shigeru
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Analysis of disease mechanism and discovery of novel treatment for neurofibromatosis type 2 using patient-derived induced pluripotent stem cell
- Principal Investigator
  
  Shunsuke Terasaka
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Hokkaido University
Exploration of methionine uptake mechanism on glioma through microRNA analysisPrincipal Investigator
- Principal Investigator
  
  YAMAGUCHI Shigeru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurosurgery
- Research Institution
  Hokkaido University

All 2024 2022 2021 2019 2017

All Journal Article Presentation

[Journal Article] Identifying G6PC3 as a Potential Key Molecule in Hypoxic Glucose Metabolism of Glioblastoma Derived from the Depiction of 18F-Fluoromisonidazole and 18F-Fluorodeoxyglucose Positron Emission Tomography2024
- Author(s)
  Okamoto Michinari、Yamaguchi Shigeru、Sawaya Ryosuke、Echizenya Sumire、Ishi Yukitomo、Kaneko Sadahiro、Motegi Hiroaki、Toyonaga Takuya、Hirata Kenji、Fujimura Miki
- Journal Title
  
  BioMed Research International
  
  Volume: 2024 Pages: 1-10
- DOI
  10.1155/2024/2973407
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09225
[Journal Article] Analysis of induced pluripotent stem cell clones derived from a patient with mosaic neurofibromatosis type 22022
- Author(s)
  Ishi Yukitomo、Era Takumi、Yuzawa Sayaka、Okamoto Michinari、Sawaya Ryosuke、Motegi Hiroaki、Yamaguchi Shigeru、Terasaka Shunsuke、Houkin Kiyohiro、Fujimura Miki
- Journal Title
  
  American Journal of Medical Genetics Part A
  
  Volume: - Issue: 6 Pages: 1863-1867
- DOI
  10.1002/ajmg.a.62700
- Data Source
  KAKENHI-PROJECT-19K09519
[Journal Article] Variations and natural history of primary intraparenchymal lesions associated with neurofibromatosis type 22021
- Author(s)
  Ishi Yukitomo、Harada Taisuke、Kameda Hiroyuki、Okada Hiromi、Yokota Isao、Okamoto Michinari、Sawaya Ryosuke、Motegi Hiroaki、Yamaguchi Shigeru、Terasaka Shunsuke、Kudo Kohsuke、Fujimura Miki
- Journal Title
  
  Neuroradiology
  
  Volume: 64 Issue: 2 Pages: 393-396
- DOI
  10.1007/s00234-021-02809-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09519, KAKENHI-PROJECT-21H02857, KAKENHI-PROJECT-19K17256
[Journal Article] Identification of PEPT2 as an Important Candidate Molecule in 5-ALA-mediated Fluorescence-Guided Surgery in WHO Grade II/III Gliomas2019
- Author(s)
  Hou C, Yamaguchi S, Ishi Y, Terasaka S, Kobayashi H, Motegi H, Hatanaka KC, Houkin K.
- Journal Title
  
  J Neurooncol
  
  Volume: 143 Issue: 2 Pages: 197-206
- DOI
  10.1007/s11060-019-03158-3
- NAID
  120006847764
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K09495
[Journal Article] PETの脳腫瘍への応用2017
- Author(s)
  山口　秀
- Journal Title
  
  脳神経外科
  
  Volume: 45 Pages: 1015-1024
- Data Source
  KAKENHI-PROJECT-16K19991
[Presentation] 蛍光診断補助装置VLD-EXを用いた深部に存在する悪性神経膠腫の摘出術2021
- Author(s)
  山口　秀
- Organizer
  第30回日本脳神経外科手術と機器学会
- Data Source
  KAKENHI-PROJECT-19K09495
[Presentation] BRAF V600変異を有する成人高悪性度神経膠腫の臨床病理学的検討2017
- Author(s)
  伊師雪友山口秀吉田道春茂木洋晃小林浩之寺坂俊介寶金清博
- Organizer
  第18回日本分子脳神経外科学会
- Data Source
  KAKENHI-PROJECT-16K19991
[Presentation] Clinicopathological Analysis of Adult High-Grade Gliomas Harboring BRAF V600E Mutation2017
- Author(s)
  Yukitomo Ishi, Shigeru Yamaguchi, Michiharu Yoshida, Hiroaki Motegi, Hiryuki Kobayashi, Shunsuke Terasaka, Kiyohiro Houkin
- Organizer
  The meeting of the Asian Society of Neuro-Oncology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19991
[Presentation] MRIとメチオニンPET所見から神経膠腫の病理診断や予後予測は可能か？2017
- Author(s)
  山口　秀、平田　健司、伊師　雪友、茂木　洋晃、小林　浩之、寺坂　俊介、寳金　清博
- Organizer
  第35回日本脳腫瘍学会
- Data Source
  KAKENHI-PROJECT-16K19991

1. 伊師雪友 (30812284)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. 小林浩之 (70374478)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 茂木洋晃 (40748844)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. Shunsuke Terasaka (10447055)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 江良択実 (00273706)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 平田健司 (30431365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 金子貞洋 (40811237)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. KO Suken

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Yamaguchi Shigeru 山口 秀

YAMAGUCHI Shigeru 山口 秀

Research Projects

Research Products

Co-Researchers

Analysis of treatment effect of combination with EZH2 inhibitor and immune checkpoint inhibitor for aypical rhabdoid / teratoid tumors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

膠芽腫における低酸素内糖代謝亢進メカニズムの検証Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Photodynamic diagnosis for low-grade gliomas: functional analysis of porphyrin synthesis pathwayPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of disease mechanism and discovery of novel treatment for neurofibromatosis type 2 using patient-derived induced pluripotent stem cell

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of methionine uptake mechanism on glioma through microRNA analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identifying G6PC3 as a Potential Key Molecule in Hypoxic Glucose Metabolism of Glioblastoma Derived from the Depiction of 18F-Fluoromisonidazole and 18F-Fluorodeoxyglucose Positron Emission Tomography2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of induced pluripotent stem cell clones derived from a patient with mosaic neurofibromatosis type 22022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Variations and natural history of primary intraparenchymal lesions associated with neurofibromatosis type 22021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of PEPT2 as an Important Candidate Molecule in 5-ALA-mediated Fluorescence-Guided Surgery in WHO Grade II/III Gliomas2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] PETの脳腫瘍への応用2017

Author(s)

Journal Title

Data Source

[Presentation] 蛍光診断補助装置VLD-EXを用いた深部に存在する悪性神経膠腫の摘出術2021

Author(s)

Organizer

Data Source

[Presentation] BRAF V600変異を有する成人高悪性度神経膠腫の臨床病理学的検討2017

Author(s)

Organizer

Data Source

[Presentation] Clinicopathological Analysis of Adult High-Grade Gliomas Harboring BRAF V600E Mutation2017

Author(s)

Organizer

Data Source

[Presentation] MRIとメチオニンPET所見から神経膠腫の病理診断や予後予測は可能か？2017

Author(s)

Organizer

Data Source

Yamaguchi Shigeru 山口秀

YAMAGUCHI Shigeru 山口秀