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Ito Takuhiro  伊藤 拓宏

… Alternative Names

ITO Takuhiro  伊藤 拓宏

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Researcher Number 70401164
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-3704-5205
Affiliation (Current) 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, チームリーダー
Affiliation (based on the past Project Information) *help 2019 – 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, チームリーダー
2018: 国立研究開発法人理化学研究所, 生命機能科学研究センター, ユニットリーダー
2015 – 2017: 国立研究開発法人理化学研究所, ライフサイエンス技術基盤研究センター, ユニットリーダー
2013 – 2014: 独立行政法人理化学研究所, ライフサイエンス技術基盤研究センター, ユニットリーダー
2012: 独立行政法人理化学研究所, その他部局等, 研究員 … More
2012: 独立行政法人理化学研究所, システム研究チーム, 研究員
2012: 独立行政法人理化学研究所, 生命分子システム基盤研究領域, 研究員
2011: 東京大学, 大学院・理学系研究科, 助教
2011: 東京大学, 大学院・理学系研究科, 特任助教
2011: 東京大学, 理学(系)研究科(研究院), 特任助教
2008 – 2009: The University of Tokyo, 大学院・理学系研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Structural biochemistry / Biological Sciences / Basic Section 43020:Structural biochemistry-related / Transformative Research Areas, Section (III)
Except Principal Investigator
Structural biochemistry / Living organism molecular science / Basic Section 43010:Molecular biology-related / Transformative Research Areas, Section (III)
Keywords
Principal Investigator
翻訳 / 生体分子 / 電子顕微鏡 / X線結晶構造解析 / 翻訳開始因子 / ウイルス / 立体構造 / eIF2 / eIF2B / X線結晶構造解析 … More / 翻訳開始 / タンパク質 / 核酸 / tRNA / 修飾塩基 / 2Aペプチド / 2Aペプチド / 統合的ストレス応答 / リボソーム / クライオ電子顕微鏡 / トモグラフィー / 単粒子解析 … More
Except Principal Investigator
リボソーム / 転写 / RNAポリメラーゼ / 転写因子 / 翻訳 / 翻訳開始因子 / X線結晶構造解析 / プラズマ / 結晶化 / 構造解析 / 翻訳制御 / RNA結合タンパク質 / lncRNA / 超天然変性タンパク質 / ノンコーディングRNA / 天然変性領域 Less
  • Research Projects

    (12 results)
  • Research Products

    (71 results)
  • Co-Researchers

    (28 People)
  •  Tissue-specific regulation of translation initiation mediated by ribosome heterogeneity

    • Principal Investigator
      藤原 俊伸
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43010:Molecular biology-related
    • Research Institution
      Kindai University
  •  Management of non-domain biopolymer research group

    • Principal Investigator
      中川 真一
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Hokkaido University
  •  Structural Analysis of Non Domain BiopolymerPrincipal Investigator

    • Principal Investigator
      伊藤 拓宏
    • Project Period (FY)
      2021 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Institute of Physical and Chemical Research
  •  Structural basis of traslation regulation by dynamic interactions between the complexesPrincipal Investigator

    • Principal Investigator
      Ito Takuhiro
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 43020:Structural biochemistry-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  ウイルスが引き起こす非標準的な翻訳機構の構造基盤Principal Investigator

    • Principal Investigator
      伊藤 拓宏
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  Molecular mechanism of ribosome hijack by the HCV IRESPrincipal Investigator

    • Principal Investigator
      Ito Takuhiro
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      Institute of Physical and Chemical Research
  •  ピコルナウイルスの2Aペプチドの終止コドン非依存的翻訳終結の構造基盤Principal Investigator

    • Principal Investigator
      伊藤 拓宏
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      Institute of Physical and Chemical Research
  •  翻訳開始因子eIF2Bの機能発現の構造基盤Principal Investigator

    • Principal Investigator
      伊藤 拓宏
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Biological Sciences
    • Research Institution
      The Institute of Physical and Chemical Research
  •  Plasma-Assisted Biological Macromolecular Crystallization

    • Principal Investigator
      ITO Tsuyohito
    • Project Period (FY)
      2011 – 2012
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Living organism molecular science
    • Research Institution
      Osaka University
  •  Structural basis for the functional mechanism of eukaryotic initiation factor eIF2Principal Investigator

    • Principal Investigator
      ITO Takuhiro
    • Project Period (FY)
      2011 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
      The University of Tokyo
  •  Crystallographic studies of macromolecular complexes in transcription and translation : RNA polymerases and the ribosome

    • Principal Investigator
      YOKOYAMA Shigeyuki
    • Project Period (FY)
      2008 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      The Institute of Physical and Chemical Research
      The University of Tokyo
      Tokyo Gakugei University
  •  Structural Basis of tRNA modification at position 37Principal Investigator

    • Principal Investigator
      ITO Takuhiro
    • Project Period (FY)
      2008 – 2009
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Structural biochemistry
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2018 2017 2016 2015 2014 2013 2010 2009 2008

All Journal Article Presentation

  • [Journal Article] Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A.2021

    • Author(s)
      36. Chen M, Asanuma M, Takahashi M, Shichino Y, Mito M, Fujiwara K, Saito H, Floor SN, Ingolia NT, Sodeoka M, Dodo K, Ito T, and Iwasaki S
    • Journal Title

      Cell Chem Biol.

      Volume: 28 Pages: 475-486

    • DOI

      10.1016/j.chembiol.2020.11.008

    • Description
      in press
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K05747, KAKENHI-PROJECT-19H03172, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-17H04998
  • [Journal Article] ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B2021

    • Author(s)
      Zyryanova Alisa F.、Kashiwagi Kazuhiro、Rato Claudia、Harding Heather P.、Crespillo-Casado Ana、Perera Luke A.、Sakamoto Ayako、Nishimoto Madoka、Yonemochi Mayumi、Shirouzu Mikako、Ito Takuhiro、Ron David
    • Journal Title

      Molecular Cell

      Volume: 81 Pages: 88-103

    • DOI

      10.1016/j.molcel.2020.10.031

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03172, KAKENHI-PROJECT-18K14644
  • [Journal Article] eIF2B-capturing viral protein NSs suppresses the integrated stress response2021

    • Author(s)
      Kashiwagi Kazuhiro、Shichino Yuichi、Osaki Tatsuya、Sakamoto Ayako、Nishimoto Madoka、Takahashi Mari、Mito Mari、Weber Friedemann、Ikeuchi Yoshiho、Iwasaki Shintaro、Ito Takuhiro
    • Journal Title

      Nature Communications

      Volume: 12 Pages: 7102-7102

    • DOI

      10.1038/s41467-021-27337-x

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K20178, KAKENHI-PROJECT-19H03172, KAKENHI-PROJECT-21K15023
  • [Journal Article] eIF2B and the Integrated Stress Response: A Structural and Mechanistic View2020

    • Author(s)
      Marintchev Assen、Ito Takuhiro
    • Journal Title

      Biochemistry

      Volume: 59 Pages: 1299-1308

    • DOI

      10.1021/acs.biochem.0c00132

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Journal Article] HCV IRES Captures an Actively Translating 80S Ribosome2019

    • Author(s)
      Yokoyama Takeshi、Machida Kodai、Iwasaki Wakana、Shigeta Tomoaki、Nishimoto Madoka、Takahashi Mari、Sakamoto Ayako、Yonemochi Mayumi、Harada Yoshie、Shigematsu Hideki、Shirouzu Mikako、Tadakuma Hisashi、Imataka Hiroaki、Ito Takuhiro
    • Journal Title

      Mol.Cell

      Volume: 印刷中 Pages: 1205-1214

    • DOI

      10.1016/j.molcel.2019.04.022

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-17H05677, KAKENHI-PROJECT-16H04756, KAKENHI-PROJECT-18K06172, KAKENHI-PROJECT-19K06533, KAKENHI-PROJECT-19K22390, KAKENHI-PLANNED-15H05931, KAKENHI-PROJECT-15H04324, KAKENHI-PROJECT-18H01838, KAKENHI-PROJECT-19H03172, KAKENHI-PROJECT-19H03197, KAKENHI-PROJECT-17H04995, KAKENHI-PLANNED-26116002
  • [Journal Article] The translation inhibitor Rocaglamide targets a bimolecular cavity between eIF4A and polypurine RNA.2019

    • Author(s)
      Iwasaki S. *, Iwasaki W., Takahashi M., Sakamoto A., Watanabe C., Shichino Y., Floor SN., Fujiwara K., Mito M., Dodo K., Sodeoka M., Imataka H., Honma T., Fukuzawa K., Ito T. *, and Ingolia NT. *
    • Journal Title

      Mol. Cell

      Volume: 73 Pages: 1-10

    • DOI

      10.1016/j.molcel.2018.11.026

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05677, KAKENHI-PROJECT-15H04324, KAKENHI-PROJECT-16H04756, KAKENHI-PROJECT-16H06276, KAKENHI-PUBLICLY-17H05679, KAKENHI-PROJECT-17H04998
  • [Journal Article] Structural basis for eIF2B inhibition in integrated stress response2019

    • Author(s)
      Kashiwagi Kazuhiro、Yokoyama Takeshi、Nishimoto Madoka、Takahashi Mari、Sakamoto Ayako、Yonemochi Mayumi、Shirouzu Mikako、Ito Takuhiro
    • Journal Title

      Science

      Volume: 364 Pages: 495-499

    • DOI

      10.1126/science.aaw4104

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-17H05677, KAKENHI-PROJECT-16H04756, KAKENHI-PROJECT-18K14644, KAKENHI-PROJECT-19H03172
  • [Journal Article] Dynamic inteaction of poly(A)-binding protein with the ribosome2018

    • Author(s)
      Machida Kodai、Shigeta Tomoaki、Yamamoto Yuki、Ito Takuhiro、Svitkin Yuri、Sonenberg Nahum、Imataka Hiroaki
    • Journal Title

      Scientific Reports

      Volume: 8 Pages: 17435-17435

    • DOI

      10.1038/s41598-018-35753-1

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05677, KAKENHI-PROJECT-15H04324, KAKENHI-PROJECT-16H04756, KAKENHI-PROJECT-17H04995, KAKENHI-PLANNED-26116002
  • [Journal Article] Trm5 and TrmD: two enzymes from distinct origins catalyze the identical tRNA modification, m1G372017

    • Author(s)
      Goto-Ito, S.
    • Journal Title

      Biomolecules

      Volume: 7

    • DOI

      10.3390/biom7010032

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01548, KAKENHI-PROJECT-16H04756
  • [Journal Article] Crystal structure of eukaryotic translation initiation factor 2B2016

    • Author(s)
      Kazuhiro Kashiwagi, Mari Takahashi, Madoka Nishimoto, Takuya B. Hiyama, Toshiaki Higo, Takashi Umehara, Kensaku Sakamoto, Takuhiro Ito, Shigeyuki Yokoyama
    • Journal Title

      Nature

      Volume: 531 Pages: 122-125

    • DOI

      10.1038/nature16991

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-15H01548, KAKENHI-PROJECT-26291035
  • [Journal Article] Expression, purification, and crystallization of Schizosaccharomyces pombe eIF2B2016

    • Author(s)
      Kazuhiro Kashiwagi, Tomoaki Shigeta, Hiroaki Imataka, Takuhiro Ito, Shigeyuki Yokoyama
    • Journal Title

      J. Structural and Functional Genomics

      Volume: 17 Pages: 33-38

    • DOI

      10.1007/s10969-016-9203-3

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PUBLICLY-15H01548, KAKENHI-PLANNED-26116002, KAKENHI-PROJECT-15H04324
  • [Journal Article] Structural basis for methyl-donor-dependent and sequence-specific binding to tRNA substrates by knotted methyltransferase TrmD.2015

    • Author(s)
      Takuhiro Ito, Isao Masuda, Ken-ichi Yoshida, Sakurako Goto-Ito, Shun-ichi Sekine, Se Won Suh, Ya-Ming Hou, Shigeyuki Yokoyama
    • Journal Title

      Proc Natl Acad Sci U S A.

      Volume: 112 Pages: 4197-205

    • DOI

      10.1073/pnas.1422981112

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01548, KAKENHI-PROJECT-25650018
  • [Journal Article] Crystal structure of the eukaryotic translation initiation factor 2A from Schizosaccharomyces pombe2014

    • Author(s)
      Kazuhiro Kashiwagi, Takuhiro Ito, Shigeyuki Yokoyama
    • Journal Title

      Journal of Structural and Functional Genomics

      Volume: -

    • DOI

      10.1007/s10969-014-9177-y

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23687013, KAKENHI-PUBLICLY-25121737
  • [Journal Article] Crystal structure of Methanocaldococcus jannaschii Trm4 complexed with sinefungin2010

    • Author(s)
      Kuratani, M., Hirano, M., Goto-Ito, S., Itoh, Y., Hikida, Y., Nishimoto, M., Sekine, SI., Bessho, Y., Ito, T., Grosjean, H. and Yokoyama, S.
    • Journal Title

      J. Mol. Biol

      Volume: 401(3) Pages: 323-333

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Structural basis for the major role of O-phosphoseryl-tRNA kinase in the UGA-specific encoding of selenocysteine2010

    • Author(s)
      Chiba, S., Itoh, Y., Sekine, S. and Yokoyama, S.
    • Journal Title

      Mol. Cell

      Volume: 39 Pages: 410-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Structural basis for the major role of O-phosphoseryl-tRNA kinase in the UGA-specific encoding of selenocysteine.2010

    • Author(s)
      Chiba, S., Itoh, Y., Sekine, S., Yokoyama, S.
    • Journal Title

      Mol.Cell 39

      Pages: 410-420

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Structure of nondiscriminating glutamyl-tRNA synthetase from Thermotoga maritima.2010

    • Author(s)
      Ito, T., et al.
    • Journal Title

      Acta.Crystallogr.D Biol.Crystallogr.

      Volume: 66 Pages: 813-820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Structure of Nondiscriminating Glutamyl-tRNA Synthetase from Thermotoga maritime2010

    • Author(s)
      Ito, T., Kiyasu, N., Matsunaga, R., Takahashi, S. and Yokoyama, S.
    • Journal Title

      Acta Crystallogr. D Biol. Crystallogr

      Volume: 66(7) Pages: 813-820

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.2010

    • Author(s)
      Ito, T., Yokoyama, S.
    • Journal Title

      Nature 467

      Pages: 612-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions.2010

    • Author(s)
      Ito, T., et al.
    • Journal Title

      Nature

      Volume: 467 Pages: 612-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Two enzymes bound to one transfer RNA assume alternative conformations for consecutive reactions2010

    • Author(s)
      Ito, T. and Yokoyama, S.
    • Journal Title

      Nature

      Volume: 467 Pages: 612-616

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Structure of selenophosphate synthetase essential for selenium incorporation into proteins and RNAs2009

    • Author(s)
      Itoh, Y., Sekine, SI., Matsumoto, E., Akasaka, R., Takemoto, C., Shirouzu, M. and Yokoyama, S.
    • Journal Title

      J. Mol. Biol

      Volume: 385 Pages: 1456-1469

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation2009

    • Author(s)
      Sakurako Goto-Ito
    • Journal Title

      Nat Struct Mol Biol 16

      Pages: 1109-1115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Journal Article] Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation2009

    • Author(s)
      Goto-Ito, S., Ito, T., Kuratani, M., Bessho, Y. and Yokoyama, S.
    • Journal Title

      Nat. Struct. Mol. Biol

      Volume: 16 Pages: 1109-1115

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Tertiary structure checkpoint at anticodon loop modification in tRNA functional maturation2009

    • Author(s)
      Goto-Ito, S., Ito, T., Kuratani, M., Bessho, Y., Yokoyama, S.
    • Journal Title

      Nat Struct Mol Biol 16

      Pages: 1109-1115

    • Data Source
      KAKENHI-PROJECT-20770077
  • [Journal Article] Crystal structure of theαsubunit of human translation initiation factor 2B2009

    • Author(s)
      Hiyama, T. B., Ito, T., Imataka, H. and Yokoyama, S.
    • Journal Title

      J. Mol. Biol

      Volume: 392 Pages: 937-951

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Crystal structure of the α subunit of human translation initiation factor 2B.2009

    • Author(s)
      Hiyama, T.B., Ito, T., Imataka, H., Yokoyama, S.
    • Journal Title

      J.Mol.Biol. 392

      Pages: 937-951

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Crystal structure of human selenocysteine tRNA2009

    • Author(s)
      Itoh, Y., Chiba, S., Sekine, SI. and Yokoyama, S.
    • Journal Title

      Nucleic Acids Res

      Volume: 37 Pages: 6259-6268

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Crystal Structure of the alpha subunit of human translation initiation factor 2B2009

    • Author(s)
      Hiyama, T.B., Ito, T., Imataka, H., Yokoyama, S
    • Journal Title

      J Mol Biol 392

      Pages: 937-951

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Journal Article] Crystal structure of archaeal tRNA(m(1)G37)methyltransferase aTrm52008

    • Author(s)
      Sakurako Goto-Ito
    • Journal Title

      Proteins 72

      Pages: 1274-1289

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Journal Article] Crystal Structure of Archaeal tRNA (m1G37) methyltransferase aTRM52008

    • Author(s)
      Goto-Ito, S., Ito, T., Ishii, R., Muto, Y., Bessho, Y., Yokoyama, S.
    • Journal Title

      PROTEINS: Structure, Function, and Bioinformatics 72

      Pages: 1274-1289

    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] eIF2B結合性ウイルスタンパク質NSsによる統合的ストレス応答抑制2021

    • Author(s)
      伊藤拓宏
    • Organizer
      第94回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] eIF2Bに結合するウイルスタンパク質NSsは統合的ストレス応答を抑制する2021

    • Author(s)
      伊藤拓宏
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] ストレス応答による翻訳開始停止機構の構造基盤~X線結晶構造解析とクライオ電子顕微鏡2020

    • Author(s)
      伊藤拓宏
    • Organizer
      第64回日本薬学会関東支部大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] 統合的ストレス応答阻害剤ISRIBの作用機序2020

    • Author(s)
      伊藤拓宏
    • Organizer
      第43回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] eIF2のリン酸化によるeIF2BのGEF活性制御の構造基盤2019

    • Author(s)
      伊藤拓宏
    • Organizer
      第42回日本分子生物学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] 翻訳の構造生物学~cryo-EMによる単粒子解析およびX線結晶構造解析、FMO法による解析例~2019

    • Author(s)
      伊藤拓宏
    • Organizer
      CBI学会第411回講演会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] HCV IRES captures an actively translating 80S ribosome to hijack the host translational machinery2019

    • Author(s)
      Ito Takuhiro
    • Organizer
      EMBO Workshop, Protein Synthesis and Translational Control
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H03172
  • [Presentation] Rocaglamide Aによる配列特異的な翻訳阻害の構造基盤2018

    • Author(s)
      伊藤拓宏
    • Organizer
      第20回日本RNA学会年会
    • Data Source
      KAKENHI-PROJECT-16H04756
  • [Presentation] Rocaglamide Aによる配列特異的な翻訳阻害の構造基盤2018

    • Author(s)
      伊藤拓宏
    • Organizer
      第20回日本RNA学会年会
    • Data Source
      KAKENHI-PUBLICLY-17H05677
  • [Presentation] Structural basis for sequence-specific translation inhibition by Rocaglamide A2018

    • Author(s)
      Ito Takuhiro
    • Organizer
      Translational Control
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04756
  • [Presentation] HCV IRES captures a translating 80S ribosome to hijack host translational machinery2018

    • Author(s)
      Ito Takuhiro
    • Organizer
      Proteins; from the Cradle to the Grave
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04756
  • [Presentation] Structural basis for sequence-specific translation inhibition by Rocaglamide A2018

    • Author(s)
      Ito Takuhiro
    • Organizer
      Translational Control
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05677
  • [Presentation] HCV IRES captures a translating 80S ribosome to hijack host translational machinery2018

    • Author(s)
      Ito Takuhiro
    • Organizer
      Proteins; from the Cradle to the Grave
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-17H05677
  • [Presentation] Structural basis for sequence-specific translation repression by eIF4A and Rocaglamide2017

    • Author(s)
      Ito, T.
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PUBLICLY-17H05677
  • [Presentation] Structural basis for sequence-specific translation repression by eIF4A and Rocaglamide2017

    • Author(s)
      Ito, T.
    • Organizer
      ConBio2017
    • Data Source
      KAKENHI-PROJECT-16H04756
  • [Presentation] Crystal sturucture of eukaryotic translation initiation factor 2B2016

    • Author(s)
      Takuhiro Ito
    • Organizer
      Nascent Chain Biology Meeting 2016
    • Place of Presentation
      富士レークホテル(山梨)
    • Year and Date
      2016-09-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-15H01548
  • [Presentation] Crystal sturucture of eukaryotic translation initiation factor 2B2016

    • Author(s)
      Takuhiro Ito
    • Organizer
      Nascent Chain Biology Meeting 2016
    • Place of Presentation
      富士レークホテル(山梨)
    • Year and Date
      2016-09-01
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16H04756
  • [Presentation] tRNA(m1G37)メチル基転移酵素TrmDの基質認識機構2015

    • Author(s)
      伊藤拓宏
    • Organizer
      BMB 2015
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2015-12-04
    • Data Source
      KAKENHI-PUBLICLY-15H01548
  • [Presentation] Structural Structural insight into the eIF2-eIF2B interaction2014

    • Author(s)
      Kashiwagi Kazuhiro, Takuhiro Ito, and Shigeyuki Yokoyama
    • Organizer
      23rd Congress and General Assembly of the International Union of Crystallography
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2014-08-11
    • Invited
    • Data Source
      KAKENHI-PROJECT-23687013
  • [Presentation] Structural insight into the interaction between eIF2B and eIF2B2014

    • Author(s)
      Kashiwagi Kazuhiro, Takuhiro Ito, and Shigeyuki Yokoyama
    • Organizer
      Translational Control 2014 in Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor, USA
    • Year and Date
      2014-09-02
    • Data Source
      KAKENHI-PUBLICLY-25121737
  • [Presentation] Structural insight into the interaction between eIF2B and eIF2B2014

    • Author(s)
      Kashiwagi Kazuhiro, Takuhiro Ito, and Shigeyuki Yokoyama
    • Organizer
      Translational Control 2014 in Cold Spring Harbor Laboratory
    • Place of Presentation
      Cold Spring Harbor, USA
    • Year and Date
      2014-09-02
    • Data Source
      KAKENHI-PROJECT-23687013
  • [Presentation] Structural Structural insight into the eIF2-eIF2B interaction2014

    • Author(s)
      Kashiwagi Kazuhiro, Takuhiro Ito, and Shigeyuki Yokoyama
    • Organizer
      23rd Congress and General Assembly of the International Union of Crystallography
    • Place of Presentation
      Montreal, Canada
    • Year and Date
      2014-08-11
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-25121737
  • [Presentation] Structural mechanism of site-specific RNA modification by the bacterial tRNA(m1G37)-methyltransferase TrmD2013

    • Author(s)
      Ito, T., Masuda, I., Yoshida, KI., Goto-ito, S., Sekine, SI., Wonsuh, S., Hou, YM. and Yokoyama, S.
    • Organizer
      7th International Conference on Structural Genomics 2013 - Structural Life Science (ICSG2013-SLS)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PROJECT-23687013
  • [Presentation] Structural mechanism of site-specific RNA modification by the bacterial tRNA(m1G37)-methyltransferase TrmD2013

    • Author(s)
      Ito, T., Masuda, I., Yoshida, KI., Goto-ito, S., Sekine, SI., Wonsuh, S., Hou, YM. and Yokoyama, S.
    • Organizer
      7th International Conference on Structural Genomics 2013 - Structural Life Science (ICSG2013-SLS)
    • Place of Presentation
      札幌
    • Data Source
      KAKENHI-PUBLICLY-25121737
  • [Presentation] Structural basis of the sequence-specific methyltransfer reaction by bacterial tRNA methyltransferase TrmD2013

    • Author(s)
      Ito, T., Masuda, I., Yoshida, KI., Goto-ito, S., Sekine, SI., Wonsuh, S., Hou, YM. and Yokoyama, S.
    • Organizer
      The 65th Fujihara Seminar International Symposium on Synthetic Biology of Unnatural Base Pairs and Amino Acids
    • Place of Presentation
      苫小牧
    • Data Source
      KAKENHI-PUBLICLY-25121737
  • [Presentation] 大気圧プラズマによる水中脱色反応の研究2013

    • Author(s)
      近藤 崇博、鷹尾 治樹、伊藤 剛仁、伊藤 拓宏、横山 茂之
    • Organizer
      2013 年春季 第60回応用物理学関連連合講演会
    • Place of Presentation
      神奈川工科大学
    • Data Source
      KAKENHI-PROJECT-23651218
  • [Presentation] Structural basis of the sequence-specific methyltransfer reaction by bacterial tRNA methyltransferase TrmD2013

    • Author(s)
      Ito, T., Masuda, I., Yoshida, KI., Goto-ito, S., Sekine, SI., Wonsuh, S., Hou, YM. and Yokoyama, S.
    • Organizer
      The 65th Fujihara Seminar International Symposium on Synthetic Biology of Unnatural Base Pairs and Amino Acids
    • Place of Presentation
      苫小牧
    • Data Source
      KAKENHI-PROJECT-23687013
  • [Presentation] 大気圧プラズマによる水中脱色反応の研究2013

    • Author(s)
      近藤崇博,鷹尾治樹,伊藤剛仁,伊藤拓宏,横山茂之
    • Organizer
      2013年春季 第60回応用物理学関連連合講演会
    • Place of Presentation
      神奈川工科大学(神奈川県)
    • Data Source
      KAKENHI-PROJECT-23651218
  • [Presentation] グルタミン-トランスアミドソームの結晶構造解析2010

    • Author(s)
      伊藤拓宏
    • Organizer
      第12回RNAミーティング
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Presentation] グルタミン-トランスアミドソームの結晶構造解析2010

    • Author(s)
      伊藤拓宏
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会合同大会(BMB2010)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Presentation] Tertiary structure checkpoint in tRNA functional maturation2010

    • Author(s)
      Takuhiro Ito
    • Organizer
      23rd tRNA workshop
    • Place of Presentation
      Averio, Portugal
    • Year and Date
      2010-01-29
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] O-ホスホセリルtRNAキナーゼとセレノシステインtRNA複合体の結晶構造2010

    • Author(s)
      伊藤弓弦
    • Organizer
      第12回RNAミーティング
    • Place of Presentation
      東京
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Presentation] Tertiary structure checkpoint in tRNA functional maturation2010

    • Author(s)
      伊藤(後藤)桜子
    • Organizer
      23^<rd> tRNA workshop
    • Place of Presentation
      Averio, Portugal
    • Year and Date
      2010-01-29
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] Crystallographic Studies of Aminoacyl-tRNA Synthesis and tRNA Modification2010

    • Author(s)
      Itoh, Y., Chiba, S., Naganuma, M., Goto-ito, S., Fukunaga, R., Kuratani, M., Bessho, Y., Ito, T., Sekine, SI., Yokoyama, S.
    • Organizer
      23rd tRNA Workshop
    • Place of Presentation
      Aveiro, Portugal
    • Year and Date
      2010-01-29
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Presentation] ゲルタミン-トランスアミドソームの結晶構造解析2010

    • Author(s)
      伊藤拓宏
    • Organizer
      第33回日本分子生物学会年会・第83回日本生化学会大会 合同大会(BMB2010)
    • Place of Presentation
      神戸
    • Data Source
      KAKENHI-PROJECT-20247008
  • [Presentation] tRNA37位のグアノシンに対するメチル基転移酵素(Trm5)は, tRNA成熟プロセスにおけるtRNAL字型立体構造のチェックポイントとして働く2009

    • Author(s)
      伊藤(後藤)桜子
    • Organizer
      第11回日本RNA学会年会
    • Place of Presentation
      朱鷺メッセ 新潟コンベンションセンター
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] tRNA 37位のグアノシンに対するメチル基転移酵素(Trm5)は, tRNA成熟プロセスにおけるtRNA L字型立体構造のチェックポイントとして働く2009

    • Author(s)
      伊藤(後藤)桜子
    • Organizer
      第11回日本RNA学会年会
    • Place of Presentation
      朱鷺メッセ新潟コンベンションセンター
    • Year and Date
      2009-07-28
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] tRNA37位のグアノシンに対するメチル基転移酵素(TRM5)によるtRNA認識機構の立体構造学的研究2008

    • Author(s)
      伊藤(後藤)桜子
    • Organizer
      第10回日本RNA学会年会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2008-07-25
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] tRNAアンチコドン隣位(37位)のグアノシンに連続的に働く修飾酵素の立体構造学的研究2008

    • Author(s)
      伊藤拓宏
    • Organizer
      第10回日本RNA学会年会
    • Place of Presentation
      札幌コンベンションセンター
    • Year and Date
      2008-07-23
    • Data Source
      KAKENHI-PROJECT-20770077
  • [Presentation] tRNA37位のグアノシンに対するメチル基転移酵素(TRM5)によるtRNA認識機構2008

    • Author(s)
      伊藤拓宏
    • Organizer
      BMB2008
    • Place of Presentation
      神戸ポートアイランド
    • Year and Date
      2008-12-12
    • Data Source
      KAKENHI-PROJECT-20770077
  • 1.  YOKOYAMA Shigeyuki (00159229)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 2.  SEKINE Shunichi (50321774)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 3.  FUJII Yoshifumi (30392096)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 4.  ITO Tsuyohito (70452472)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 5.  藤原 俊伸 (80362804)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  三嶋 雄一郎 (00557069)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  中川 真一 (50324679)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  廣瀬 哲郎 (30273220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  尾山 大明 (30422398)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  稲田 利文 (40242812)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  荒川 和晴 (40453550)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  甲斐 歳恵 (40579786)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  依田 隆夫 (50367900)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  泊 幸秀 (90447368)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  西増 弘志 (00467044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  IMATAKA hiroaki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 7 results
  • 17.  SHIGEMATSU hideki
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 18.  YOKOYAMA takeshi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 19.  KASHIWAGI kazuhiro
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 20.  IWASAKI Shintaro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 21.  岩崎 わかな
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 22.  多田隈 尚史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 23.  原田 慶恵
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 24.  町田 幸大
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 25.  坂本 健作
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 26.  高橋 智
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 27.  どど 孝介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 28.  伊藤 桜子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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