Hayashi Shigehiko 林重彦

… Alternative Names

Researcher Number	70402758
Other IDs
External Links
Affiliation (Current)	2019: 京都大学, 理学研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2019: 京都大学, 理学研究科, 教授 2013 – 2015: 京都大学, 理学(系)研究科(研究院), 教授 2013: 京都大学, 大学院・理学研究科, 教授 2012: 京都大学, 大学院・理学研究科, 准教授 2011 – 2012: 京都大学, 理学(系)研究科(研究院), 准教授 … More
Review Section/Research Field	Principal Investigator Biophysics / Science and Engineering / Biological Sciences / Basic Section 43040:Biophysics-related Except Principal Investigator Biological Sciences / Biophysics / Science and Engineering
Keywords	Principal Investigator 分子シミュレーション / 酵素反応 / 分子動力学法 / QM/MM 法 / 分子モーター / 酵素設計 / 量子化学計算 / ハイブリッド法 / シグナル伝達タンパク質 / 光受容体タンパク質 … More Except Principal Investigator 生物物理 / ナノバイオ / 1分子計測 / 分子モーター / MEMS / MD/QM / MD / QM / 回転分子モーター / 生体膜 / エネルギー変換 / 分子シミュレーション / 1 分子計測 / ナノバイオロジー / ナノバイオテクノロジー / ATP合成酵素 / べん毛モーター / マイクロ / 色 / タンパク質 / 光 / 実験と理論の融合 / シグナル伝達 / 生体分子 / 分子認識 / 分子機械 / 超分子化学 / ロドプシン / 分子複雑系 / 理論・計算 / 先端計測 / 機能創成 / 分子科学 Less

Theoretical Study on molecular mechanisms of functional processes of biological moleculesPrincipal InvestigatorOngoing
- Principal Investigator
  
  林重彦
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Theoretical determination of protonation states of the manganese cluster in photosystem IIPrincipal InvestigatorOngoing
- Principal Investigator
  
  林重彦
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Research Institution
  Kyoto University
Theoretical Study of Molecular functions of ProteinsPrincipal Investigator
- Principal Investigator
  
  林重彦
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
Support for International Activities of Studying the Function of Soft Molecular Systems by Concerted Use of Theory and Experiment
- Principal Investigator
  
  TAHARA Tahei
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Institute of Physical and Chemical Research
Theoretical Analysis and Rational Design of Catalytic Activity of Flexible MoleculesPrincipal Investigator
- Principal Investigator
  
  HAYASHI Shigehiko
- Project Period (FY)
  2013 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Theoretical study on molecular mechanisms of protein functionsPrincipal Investigator
- Principal Investigator
  
  Hayashi Shigehiko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
タンパク質機能におけるｐＫａ制御の分子機構Principal Investigator
- Principal Investigator
  
  林重彦
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Science and Engineering
- Research Institution
  Kyoto University
Investigation of color tuning mechanism in rhodopsins and production of multi-colored pigments
- Principal Investigator
  
  SUDO Yuki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biophysics
- Research Institution
  Nagoya University
Theoretical study of molecular mechanism of protein functionsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Shigehiko
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
Molecular mechanism of chemical-mechanical energy conversion of F1 molecular motor studied by molecular simulationsPrincipal Investigator
- Principal Investigator
  
  HAYASHI Shigehiko
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
Innovative nanoscience of supermolecular motor proteins working in biomembranes
- Principal Investigator
  
  NOJI Hiroyuki
- Project Period (FY)
  2006 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  The University of Tokyo
  Osaka University

[Book] 岩波講座計算科学第 4 巻　計算と生命, 第 3.3 章2012
- Author(s)
  林重彦
- Publisher
  岩波書店
- Data Source
  KAKENHI-PROJECT-22370058
[Book] タンパク質の生物学的機能と化学反応, 岩波講座計算科学第4 巻計算と生命, 第3.3 章2012
- Author(s)
  林重彦
- Data Source
  KAKENHI-PROJECT-22370058
[Book] 酵素反応と生体分子機能の分子シミュレーション. CSJ カレントレヴュー・巨大分子系の計算化学, 08, 第17 章2012
- Author(s)
  林重彦
- Data Source
  KAKENHI-PROJECT-22370058
[Book] 岩波講座計算科学第 4 巻　計算と生命, 第 3.3 章2012
- Author(s)
  林重彦
- Publisher
  岩波書店
- Data Source
  KAKENHI-PUBLICLY-23107717
[Journal Article] An Atomistic Model of a Precursor State of Light-Induced Channel Opening of Channelrhodopsin2018
- Author(s)
  Cheng Cheng, Motoshi Kamiya, Mizuki Takemoto, Ryuichiro Ishitani, Osamu Nureki, *Norio Yoshida, and *Shigehiko Hayashi
- Journal Title
  
  Biophys. J.
  
  Volume: 115 Pages: 1281-1291
- DOI
  10.1016/j.bpj.2018.08.024
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-18H05161, KAKENHI-PROJECT-16H04776, KAKENHI-PROJECT-17H03640, KAKENHI-PROJECT-16J11404, KAKENHI-PROJECT-16K05519, KAKENHI-PROJECT-16H06294
[Journal Article] QM/MM geometry optimization on extensive free-energy surfaces for examination of enzymatic reactions and design of novel functional properties of proteins2017
- Author(s)
  Shigehiko Hayashi*, Yoshihiro Uchida, Taisuke Hasegawa, Masahiro Higashi, Takahiro Kosugi, and Motoshi Kamiya
- Journal Title
  
  Annual Review of Physical Chemistry
  
  Volume: 63 Pages: 135-154
- DOI
  10.1146/annurev-physchem-052516-050827
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-16H04776
[Journal Article] 1.Photoactivation intermediates of a G-protein coupled receptor rhodopsin investigated by a hybrid molecular simulation.2017
- Author(s)
  Motoshi Kamiya and Shigehiko Hayashi*
- Journal Title
  
  Journal of Physical Chemistry B
  
  Volume: 121 Pages: 3842-3852
- DOI
  10.1021/acs.jpcb.6b13050
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-16H04776
[Journal Article] Polyaromatic Nanocapsule as a Sucrose Receptor in Water2017
- Author(s)
  Masahiro Yamashina, Munetaka Akita, Taisuke Hasegawa, Shigehiko Hayashi, and Michito Yoshizawa*
- Journal Title
  
  Science Adv.
  
  Volume: 3
- DOI
  10.1126/sciadv.1701126
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PLANNED-25104011, KAKENHI-PROJECT-16H04776, KAKENHI-PROJECT-16K13947, KAKENHI-PUBLICLY-17H05359
[Journal Article] ハイブリッド分子シミュレーションによるロドプシン光受容体の分子機能の理解と設計2017
- Author(s)
  林重彦
- Journal Title
  
  医学のあゆみ - 第5土曜特集号「生命現象を観る－革新的な構造生命科学が観せてくれる世界」
  
  Volume: 262 Pages: 552-558
- Data Source
  KAKENHI-PROJECT-16H04776
[Journal Article] Atomistic modeling of alternating access of a mitochondrial ADP/ATP membrane transporter with molecular simulations.2017
- Author(s)
  Koichi Tamura and Shigehiko Hayashi*
- Journal Title
  
  PLOS ONE
  
  Volume: 12
- DOI
  10.1371/journal.pone.0181489
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-16H04776
[Journal Article] ハイブリッド分子シミュレーションによるロドプシン光受容体の分子機能の理解と設計2017
- Author(s)
  林　重彦
- Journal Title
  
  医学のあゆみ - 第5土曜特集号「生命現象を観る－革新的な構造生命科学が観せてくれる世界」
  
  Volume: 262 Pages: 552-558
- Data Source
  KAKENHI-PLANNED-25104004
[Journal Article] X-ray Crystallographic Structure of Thermophilic Rhodopsin: Implications for High Thermal Stability and Optogenetic Function2016
- Author(s)
  Tsukamoto T, Mizutani K, Hasegawa T, Takahashi M, Honda N, Hashimoto N, Shimono K, Yamashita K, Yamamoto M, Miyauchi S, Takagi S, Hayashi S, Murata T, Sudo Y
- Journal Title
  
  The Journal of Biological Chemistry
  
  Volume: 291 Pages: 12223-12232
- DOI
  10.1074/jbc.m116.719815
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25250002, KAKENHI-PUBLICLY-15H00878, KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-15H04363, KAKENHI-PROJECT-16H04776, KAKENHI-PROJECT-26460044, KAKENHI-PROJECT-15K12769, KAKENHI-PROJECT-15K18519
[Journal Article] Atomistic design of microbial opsin-based blue-shifted optogenetics tools.2015
- Author(s)
  Kato HE, Kamiya M, Sugo S, Ito J, Taniguchi R, Orito A, Hirata K, Inutsuka A,Yamanaka A, Maturana AD, Ishitani R, Sudo Y, Hayashi S, Nureki O
- Journal Title
  
  Nat Commun.
  
  Volume: 6 Pages: 7177-7177
- DOI
  10.1038/ncomms8177
- NAID
  120005745621
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26640041, KAKENHI-PUBLICLY-15H00878, KAKENHI-PUBLICLY-15H01428, KAKENHI-PLANNED-25104004, KAKENHI-PUBLICLY-26118507, KAKENHI-PROJECT-15H04363, KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-26860157, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25291034, KAKENHI-PROJECT-26293046
[Journal Article] Molecular mechanism of wide photoabsorption spectral shifts of color variants of human cellular retinol binding protein II2015
- Author(s)
  Cheng Cheng, Motoshi Kamiya, Yoshihiro Uchida, and Shigehiko Hayashi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 137 Pages: 13362-13370
- DOI
  10.1021/jacs.5b08316
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-25291034
[Journal Article] Key chemical factors of arginine finger catalysis of F1-ATPase clarified by an unnatural amino acid mutation2015
- Author(s)
  Yukawa A, Iino R, Watanabe R, Hayashi S and Noji H
- Journal Title
  
  Biochemistry
  
  Volume: 54 Pages: 472-480
- DOI
  10.1021/bi501138b
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-23115002, KAKENHI-PLANNED-25104004, KAKENHI-PUBLICLY-25117505, KAKENHI-PROJECT-25251016, KAKENHI-PROJECT-25291034, KAKENHI-PUBLICLY-26102507
[Journal Article] Role of Bulk Water Environment in Regulation of Functional Hydrogen-Bond Network in Photoactive Yellow Protein2015
- Author(s)
  Koichi Tamura and Shigehiko Hayashi
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 119 Pages: 15537-15549
- DOI
  10.1021/acs.jpcb.5b07555
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-14J01431, KAKENHI-PROJECT-25291034
[Journal Article] Molecular Dynamics of Channelrhodopsin at the Early Stages of Channel Opening.2015
- Author(s)
  Mizuki Takemoto, Hideaki E. Kato, Michio Koyama, Jumpei Ito, Motoshi Kamiya, Shigehiko Hayashi, Andres D. Maturana, Karl Deisseroth, Ryuichiro Ishitani, and Osamu Nureki
- Journal Title
  
  PLoS One
  
  Volume: 10 Pages: 0131094-0131094
- DOI
  10.1371/journal.pone.0131094
- NAID
  120005947158
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-15J08129, KAKENHI-PROJECT-14J02967, KAKENHI-PROJECT-25291011, KAKENHI-PROJECT-25291034
[Journal Article] Converting a Light-driven Proton Pump into a Light-gated Proton Channel2015
- Author(s)
  K. Inoue, T. Tsukamoto, K. Shimono, Y. Suzuki, S. Miyauchi, S. Hayashi, H. Kandori, Y. Sudo*
- Journal Title
  
  J Am Chem Soc
  
  Volume: 137 Pages: 3291-3299
- DOI
  10.1021/ja511788f
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-22247024, KAKENHI-PROJECT-23687019, KAKENHI-PLANNED-25104004, KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-25291034, KAKENHI-PUBLICLY-26115706, KAKENHI-PROJECT-26460044, KAKENHI-PROJECT-26620005, KAKENHI-PROJECT-26708001
[Journal Article] Linear Response Path Following: A Molecular Dynamics Method To Simulate Global Conformational Changes of Protein upon Ligand Binding2015
- Author(s)
  Koichi Tamura and Shigehiko Hayashi
- Journal Title
  
  Journal of Chemical Theory and Computation
  
  Volume: 11 Pages: 2900-2917
- DOI
  10.1021/acs.jctc.5b00120
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-14J01431, KAKENHI-PROJECT-25291034
[Journal Article] Silencing neurons with light2014
- Author(s)
  Shigehiko Hayashi
- Journal Title
  
  Science
  
  Volume: 344 Pages: 369-370
- DOI
  10.1126/science.1253616
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-25291034
[Journal Article] Theoretical Study on Excited States of Bacteriochlorophyll a in Solutions with Density Functional Assessment2014
- Author(s)
  Masahiro Higashi, Takahiro Kosugi, Shigehiko Hayashi, and Shinji Saito
- Journal Title
  
  The Journal of Physical Chemistry B
  
  Volume: 118 Pages: 10906-101918
- DOI
  10.1021/jp507259g
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-25288011, KAKENHI-PROJECT-25291034, KAKENHI-PROJECT-26810008
[Journal Article] The reaction mechanism of Claisen rearrangement obtained by transition state spectroscopy and single direct-dynamics trajectory2013
- Author(s)
  Izumi Iwakura, Yu Kaneko, Shigehiko Hayashi, Atsushi Yabushita, andTakayoshi Kobayashi
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 1995-2004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] The reaction mechanism of Claisen rearrangement obtained by transition state spectroscopy and single direct-dynamics trajectory2013
- Author(s)
  Izumi Iwakura, Yu Kaneko, Shigehiko Hayashi, Atsushi Yabushita, and Takayoshi Kobayashi
- Journal Title
  
  Molecules
  
  Volume: 18 Pages: 1995-2004
- DOI
  10.3390/molecules18021995
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23107717
[Journal Article] Expression, purification and biochemical characterization of the cytoplasmic loop of PomA, a stator component of the Na<sup>+</sup> driven flagellar motor2013
- Author(s)
  Abe R
- Journal Title
  
  BIOPHYSICS
  
  Volume: 9 Issue: 0 Pages: 21-29
- DOI
  10.2142/biophysics.9.21
- NAID
  130003366026
- ISSN
  1349-2942
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23370053, KAKENHI-PROJECT-23657100, KAKENHI-PROJECT-23687019, KAKENHI-PROJECT-24657074, KAKENHI-PROJECT-24657099, KAKENHI-PUBLICLY-24121712
[Journal Article] "A blue-shifted light-driven proton pump for neural silencing"2013
- Author(s)
  Sudo, Y., Okazaki, A., Ono, H., Yagasaki, J., Sugo, S., Kamiya, M., Reissig, L., Inoue, K., Ihara, K., Kandori, H., Takagi, S., Hayashi, S.
- Journal Title
  
  J Biol Chem
  
  Volume: 288 Pages: 20624-20624
- DOI
  10.1074/jbc.m113.475533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-13F03076, KAKENHI-PROJECT-21570243, KAKENHI-PROJECT-22247024, KAKENHI-PROJECT-22300126, KAKENHI-PROJECT-23657100, KAKENHI-PROJECT-23687019, KAKENHI-PUBLICLY-24121712, KAKENHI-PROJECT-24370066, KAKENHI-PLANNED-25104009, KAKENHI-PROJECT-25291034, KAKENHI-PROJECT-25560424
[Journal Article] Structural and spectral characterizations of C1C2 channelrhodopsin and its mutants by molecular simulations2013
- Author(s)
  Motoshi Kamiya, Hideaki E. Kato, Ryuichiro Ishitani, Osamu Nureki, and Shigehiko Hayashi
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 556 Pages: 266-271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] A blue-shifted light-driven proton pump for neural silencing2013
- Author(s)
  Sudo, Y., Okazaki, A., Ono, H., Yagasaki, J., Sugo, S., Kamiya, M., Reissig, L., Inoue, K., Ihara, K., Kandori, H., Takagi, S., & Hayashi, S
- Journal Title
  
  J. Biol. Chem
  
  Volume: 288 Pages: 20624-20632
- Data Source
  KAKENHI-PROJECT-23657100
[Journal Article] Structural and spectral characterizations of C1C2 channelrhodopsin and its mutants by molecular simulations2013
- Author(s)
  Motoshi Kamiya, Hideaki E. Kato, Ryuichiro Ishitani, Osamu Nureki, Shigehiko Hayashi
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 556 Pages: 266-271
- DOI
  10.1016/j.cplett.2012.11.066
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-11J06643, KAKENHI-PUBLICLY-23107717
[Journal Article] Facile catch and release of fullerenes using a photoresponsive molecular tube2013
- Author(s)
  N. Kishi, M. Akita, M. Kamiya, S. Hayashi, H. -F. Hsu, M. Yoshizawa
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 135 Pages: 12976-12979
- DOI
  10.1021/ja406893y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J04743, KAKENHI-PLANNED-25104004, KAKENHI-PROJECT-25291034
[Journal Article] Folding Coupled with Assembly in Split Green Fluorescent Proteins Studied by Structure-Based Molecular Simulations2013
- Author(s)
  M. J. McGrath、I-F. W. Kuo, S.Hayashi, S. Takada
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: (in press) Pages: 8908-891
- DOI
  10.1021/ja401540g
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370057, KAKENHI-PUBLICLY-23107716, KAKENHI-PROJECT-23657100, KAKENHI-PUBLICLY-25118509, KAKENHI-PROJECT-25251019, KAKENHI-PROJECT-25291034
[Journal Article] Crucial role of protein flexibility in formation of a stable reaction transition state in an □-amylase catalysis.2012
- Author(s)
  Takahiro Kosugi and Shigehiko Hayashi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 134 Pages: 7045-7055
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] Molecular mechanism of ATP hydrolysis in F_1-ATPase revealed by molecular simulations and single molecule observations2012
- Author(s)
  Shigehiko Hayashi, Hiroshi Ueno, Abdul Rajjak Shaikh, Myco Umemura, Motoshi Kamiya, Yuko Ito, Mitsunori Ikeguchi、Yoshihito Komoriya, Ryota Iino, and Hiroyuki Noji
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 134 Pages: 8447-8454
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] QM/MM reweighting free energy SCF for geometry optimization on extensive free energy surface of enzymatic reaction2012
- Author(s)
  Takahiro Kosugi, Shigehiko Hayashi
- Journal Title
  
  Journal of Chemical Theory and Computation
  
  Volume: 8 Pages: 322-334
- DOI
  10.1021/ct2005837
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23107717
[Journal Article] QM/MM reweighting free energy SCF for geometry optimization on extensive free energy surface of enzymatic reaction2012
- Author(s)
  Takahiro Kosugi and Shigehiko Hayashi
- Journal Title
  
  Journal of Chemical Theory and Computation
  
  Volume: 8 Pages: 322-334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] Crucial role of protein flexibility in formation of a stable reaction transition state in an alpha-amylase catalysis2012
- Author(s)
  Takahiro Kosugi and Shigehiko Hayashi
- Journal Title
  
  Journal of the American Chemical Society
  
  Volume: 134 Pages: 7045-7055
- DOI
  10.1021/ja212117m
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-23107717
[Journal Article] Crystal structure of the channelrhodopsin light-gated cation channel2012
- Author(s)
  Kato HE, Zhang F, Yizhar O, Ramakrishnan C, Nishizawa T, Hirata K, Ito J, Aita Y, Tsukazaki T, Hayashi S, Hegemann P, Maturana AD, Ishitani R, Deisseroth K, Nureki O
- Journal Title
  
  Nature
  
  Volume: 482 Pages: 369-374
- Data Source
  KAKENHI-PROJECT-23657100
[Journal Article] Molecular mechanism of ATP hydrolysis in F1-ATPase revealed by molecular simulations and single molecule observations.2012
- Author(s)
  Shigehiko Hayashi, Hiroshi Ueno, Abdul Rajjak Shaikh, Myco Umemura, Motoshi Kamiya, Yuko Ito, Mitsunori Ikeguchi, Yoshihiro Momoriya, Ryota Iino, Hiroyuki Noji
- Journal Title
  
  J. Am. Chem. Soc.
  
  Volume: 134 Pages: 8447-8454
- DOI
  10.1021/ja211027m
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J07915, KAKENHI-PROJECT-22247025, KAKENHI-PROJECT-22300102, KAKENHI-PROJECT-22370058, KAKENHI-PROJECT-24651167, KAKENHI-PUBLICLY-23107717, KAKENHI-PUBLICLY-23107720
[Journal Article] Crystal structure of the channelrhodopsin light-gated cation channel2012
- Author(s)
  Hideaki E. Kato, Feng Zhang, Ofer Yizhar, Charu Ramakrishnan, Tomohiro Nishizawa, Kunio Hirata, Jumpei Ito, Yusuke Aita, Tomoya Tsukazaki, Shigehiko Hayashi, Peter Hegemann, Andres D. Maturana, Ryuichiro Ishitani, Karl Deisseroth, and Osamu Nureki
- Journal Title
  
  Nature
  
  Volume: 482 Pages: 369-374
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] Local entropy difference upon a substrate binding of a psychrophilic α-amylase and a mesophilic homologue2011
- Author(s)
  T.Kosugi, S.Hayashi
- Journal Title
  
  Chemical Physics Letters vol.501
  
  Pages: 517-522
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] A theoretical study on excited state double proton transfer reaction of a 7-azaindole dimer : an ab initio potential energy surface and its empirical valence bond model2011
- Author(s)
  K. Ando, S. Hayashi, S. Kato
- Journal Title
  
  Phys. Chem. Chem. Phys.
  
  Volume: 13 Pages: 11118-11127
- DOI
  10.1039/c1cp20420c
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21350010, KAKENHI-PUBLICLY-23107717, KAKENHI-PROJECT-23657100
[Journal Article] Local entropy difference upon a substrate binding of a psychrophilic α-amylase and a mesophilic homologue2011
- Author(s)
  Takahiro Kosugi, Shigehiko Hayashi
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 501 Pages: 517-522
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Local entropy difference upon a substrate binding of a psychrophilic □-amylase and a mesophilic homologue2011
- Author(s)
  Takahiro Kosugi and Shigehiko Hayashi
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 501 Pages: 517-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] A theoretical study on excited state double proton transfer reaction of a7-azaindole dimer: an ab initio potential energy surface and its empirical valence bond model2011
- Author(s)
  Kohei Ando, Shigehiko Hayashi, and Shigeki Kato
- Journal Title
  
  Physical Chemistry Chemical Physics
  
  Volume: 13 Pages: 11118-11127
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] Local entropy difference upon a substrate binding of a psychrophilic α-amylase and a mesophilic homologue2011
- Author(s)
  Takahiro Kosugi, Shigehiko Hayashi
- Journal Title
  
  Chemical Physics Letters
  
  Volume: 501 Pages: 517-522
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] Protein collective motions coupled to ligand migration in myoglobin2010
- Author(s)
  Yasutaka Nishihara, Shigeki Kato, Shigehiko Hayashi
- Journal Title
  
  Biophysical Journal
  
  Volume: 98 Pages: 1649-1657
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22370058
[Journal Article] Protein collective motions coupled to ligand migration in myoglobin2010
- Author(s)
  Y.Nishihara, S.Kato, S.Hayashi
- Journal Title
  
  Biophysical Journal vol.98
  
  Pages: 1649-1657
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Protein collective motions coupled to ligand migration in myoglobin2010
- Author(s)
  Yasutaka Nishihara, Shigeki Kato, Shigehiko Hayashi
- Journal Title
  
  Biophysical Journal
  
  Volume: 98 Pages: 1649-1657
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Photochemical reaction dynamics of the primary event of vision studied by means of a hybrid molecular simulation2009
- Author(s)
  Shigehiko Hayashi, Emad Tajkhorshid, and Klaus Schulten
- Journal Title
  
  Biophysical Journal 96
  
  Pages: 403-416
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Proton transfer reactions in reaction center of photosynthetic bacteria,Rhodobacter sphaeroides2009
- Author(s)
  Y.Kaneko, S.Hayashi, I.Ohmine
- Journal Title
  
  Journal of Physical Chemistry B vol.113
  
  Pages: 8993-9003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Electronic coulombic coupling of excitation-energy transfer in xanthorhodopsin2009
- Author(s)
  Kazuhiro Fujimoto, Shigehiko Hayashi
- Journal Title
  
  Journal of the American Chemical Society 131
  
  Pages: 14152-14153
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Proton transfer reactions in reaction center of photosynthetic bacteria, Rhodobacter sphaeroides2009
- Author(s)
  Yu Kaneko, Shigehiko Hayashi, Iwao Ohmine
- Journal Title
  
  Journal of Physical Chemistry B 113
  
  Pages: 8993-9003
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Mechanism of efficient firefly bioluminescence via adiabatic transition state and seam of sloped conical intersection2008
- Author(s)
  Lung Wa Chung, Shigehiko Hayashi, Marcus Lundberg, Toru Nakatsu, Hiroaki Kato, and Keiji Morokuma
- Journal Title
  
  Journal of the American Chemical Society 130
  
  Pages: 12880-12881
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] A search for ligand diffusion pathway in mioglobin using a metadynamics simulation2008
- Author(s)
  Yasutaka Nishihara, Shigehiko Hayashi, and Shigeki Kato
- Journal Title
  
  Chemical Physics Letters 464
  
  Pages: 220-225
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Transition state determination of enzyme reaction on free energy surface: Application to chorismate mutase.2007
- Author(s)
  Higashi, M., Hayashi, S., Kato, S.
- Journal Title
  
  Chem. Phys. Lett. 437
  
  Pages: 293-297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] 分子シミュレーションによるF1-ATPaseの構造機能解析2007
- Author(s)
  林重彦
- Journal Title
  
  蛋白質核酸酵素 52・4
  
  Pages: 329-334
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Transition state determination of enzyme reaction on free energy surface: Application to chorismate mutase2007
- Author(s)
  M.Higashi, S.Hayashi, S.Kato
- Journal Title
  
  Chemical Physics Letters vol.437
  
  Pages: 293-297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Transition state determination of enzyme reaction on free energy surface: Application to chorismate mutase2007
- Author(s)
  Masahiro Higashi, Shigehiko Hayashi, and Shigeki Kato
- Journal Title
  
  Chemical Physics Letters 437
  
  Pages: 293-297
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Transition state determination of enzyme reaction on free energy surface : Application to chorismate mutase2007
- Author(s)
  M.Higashi, S.Hayashi, S.Kato
- Journal Title
  
  Chem.Phys.Lett. 437
  
  Pages: 293-297
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] 分子シミュレーションによるF1-ATPaseの構造機能解析2007
- Author(s)
  林重彦
- Journal Title
  
  蛋白質核酸酵素 52
  
  Pages: 329-334
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] Geometry optimization based on linear response free energy with quantum mechanical/molecular mechanical method: Applications to Menshutkin-type and Claisen rearrangement reactions in aqueous solution.2007
- Author(s)
  Masahiro Higashi, Shigehiko Hayashi, and Shigeki Kato
- Journal Title
  
  Journal of Chemical Physics 126
  
  Pages: 144503-144503
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-18074004
[Journal Article] 分子シミュレーションによるF1-ATPaseの構造機能解析2007
- Author(s)
  林重彦
- Journal Title
  
  蛋白質核酸酵素 vol.52
  
  Pages: 329-334
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] 分子シミュレーションによるAsLOV2光受容タンパク質の光活性化中間状態2019
- Author(s)
  田口真彦、成セイ、東村智佳、内田芳裕、林重彦
- Organizer
  第16回京都大学福井謙一記念研究センターシンポジウム
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] 分子シミュレーションによるAsLOV2光受容タンパク質の光活性化中間状態2019
- Author(s)
  田口真彦、成セイ、東村智佳、内田芳裕、林重彦
- Organizer
  第16回京都大学福井謙一記念研究センターシンポジウム
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Functional molecular dynamics of rhodopsins revealed by hybrid molecular simulations2018
- Author(s)
  Shigehiko Hayashi
- Organizer
  18th International Conference on Retinal Proteins
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Photoactivation Intermediate of AsLOV2 Photoreceptor Protein Investigated by a Hybrid Molecular Simulation2018
- Author(s)
  Masahiko Taguchi, Cheng Cheng, Chika Higashimura, Shigehiko Hayashi
- Organizer
  FUKUI 2018 Satelite Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] 柔らかな分子がもたらす分子機能の理解と設計2018
- Author(s)
  林　重彦
- Organizer
  近畿化学協会コンピュータ化学部会（第103回例会）公開講演会「大規模シミュレーションによる機能発現の理解～分子領域からマクロ領域まで～
- Invited
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Functional Molecular Dynamics of Photo-Receptor Proteins Revealed by a Hybrid Molecular Simulation Technique2018
- Author(s)
  林　重彦
- Organizer
  第56回日本生物物理学会・シンポジウム “マルチスケール・フィジクスで見えてくる生体高分子のダイナミクスと機能機序”
- Invited
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Functional Molecular Dynamics of Photo-Receptor Proteins Revealed by a Hybrid Molecular Simulation Technique2018
- Author(s)
  林　重彦
- Organizer
  第56回日本生物物理学会・シンポジウム “マルチスケール・フィジクスで見えてくる生体高分子のダイナミクスと機能機序”
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Molecular simulation on light-activation mechanism of LOV photoreceptor protein2018
- Author(s)
  Masahiko Taguchi, Cheng Cheng, Chika Higashimura, Shigehiko Hayashi
- Organizer
  第56回日本生物物理学会
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Theoretical study on molecular mechanism of a light-driven ion transport of Halorhodopsin2018
- Author(s)
  Ryo Oyama,Taisuke Hasegawa,Shigehiko Hayashi
- Organizer
  第56回日本生物物理学会
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Theoretical study on molecular mechanism of a light-driven ion transport of Halorhodopsin2018
- Author(s)
  Ryo Oyama,Taisuke Hasegawa,Shigehiko Hayashi
- Organizer
  第56回日本生物物理学会
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Functional molecular dynamics of rhodopsins revealed by hybrid molecular simulations2018
- Author(s)
  Shigehiko Hayashi
- Organizer
  18th International Conference on Retinal Proteins
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Ab initio evaluation of redox potential of metalloprotein2018
- Author(s)
  Cheng Cheng, Shigehiko Hayashi
- Organizer
  第56回日本生物物理学会
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] 柔らかな分子がもたらす分子機能の理解と設計2018
- Author(s)
  林　重彦
- Organizer
  近畿化学協会コンピュータ化学部会（第103回例会）公開講演会「大規模シミュレーションによる機能発現の理解～分子領域からマクロ領域まで～
- Invited
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Functional Molecular Dynamics of Photo-Receptor Proteins Revealed by a Hybrid Molecular Simulation Technique2018
- Author(s)
  Shigehiko Hayashi
- Organizer
  Indo-Japan mini-workshop “Frontiers in Molecular Spectroscopy: From Fundamentals to Applications in Chemistry and Biology”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Functional Molecular Dynamics of Photo-Receptor Proteins Revealed by a Hybrid Molecular Simulation Technique2018
- Author(s)
  Shigehiko Hayashi
- Organizer
  Indo-Japan mini-workshop “Frontiers in Molecular Spectroscopy: From Fundamentals to Applications in Chemistry and Biology”
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Molecular simulation on light-activation mechanism of LOV photoreceptor protein2018
- Author(s)
  Masahiko Taguchi, Cheng Cheng, Chika Higashimura, Shigehiko Hayashi
- Organizer
  第56回日本生物物理学会
- Data Source
  KAKENHI-PUBLICLY-18H05161
[Presentation] Photoactivation Intermediate of AsLOV2 Photoreceptor Protein Investigated by a Hybrid Molecular Simulation2018
- Author(s)
  Masahiko Taguchi, Cheng Cheng, Chika Higashimura, Shigehiko Hayashi
- Organizer
  FUKUI 2018 Satelite Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Ab initio evaluation of redox potential of metalloprotein2018
- Author(s)
  Cheng Cheng, Shigehiko Hayashi
- Organizer
  第56回日本生物物理学会
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] 超分子カプセルの分子内包能と動的挙動2017
- Author(s)
  林　重彦、吉沢道人
- Organizer
  日本化学会第97春季年会　シンポジウム「複雑系のための分子科学―理論、計測、合成の連携で拓く柔らかな分子の新機能」
- Place of Presentation
  日吉・神奈川
- Year and Date
  2017-03-16
- Invited
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Understanding and designing color variants of retinal binding proteins by molecular simulations2017
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on “Protein Dynamics” (Telluride, USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 超分子カプセルの分子内包能と動的挙動2017
- Author(s)
  林　重彦、吉沢道人
- Organizer
  日本化学会第97春季年会　シンポジウム「複雑系のための分子科学―理論、計測、合成の連携で拓く柔らかな分子の新機能」
- Place of Presentation
  日吉・神奈川
- Year and Date
  2017-03-16
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Understanding and designing color variants of retinal binding proteins by molecular simulations2017
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on “Protein Dynamics” (Telluride, USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Understanding and designing color variants of retinal binding proteins by molecular simulations2017
- Author(s)
  Shigehiko Hayashi
- Organizer
  253rd American Chemical Society National Meeting (San Francisco, USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Understanding and designing color variants of retinal binding proteins by molecular simulations2017
- Author(s)
  Shigehiko Hayashi
- Organizer
  253rd American Chemical Society National Meeting (San Francisco, USA)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2016
- Author(s)
  Shigehiko Hayashi
- Organizer
  IAS Focused Program on “Molecular Machines of Life: Simulations Meets Experiment
- Place of Presentation
  香港・中国
- Year and Date
  2016-05-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2016
- Author(s)
  Shigehiko Hayashi
- Organizer
  Japan-France-Spain Joint-Symposium on Theoretical and Computational Science of Complex Systems
- Place of Presentation
  京都
- Year and Date
  2016-10-26
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2016
- Author(s)
  Shigehiko Hayashi
- Organizer
  The 16th KIAS Conference on Protein Structure and Function
- Place of Presentation
  ソウル・韓国
- Year and Date
  2016-09-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 柔らかいタンパク質の分子機能理解と設計2016
- Author(s)
  林　重彦
- Organizer
  第10回分子科学討論会
- Place of Presentation
  神戸・兵庫
- Year and Date
  2016-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2016
- Author(s)
  Shigehiko Hayashi
- Organizer
  IAS Focused Program on “Molecular Machines of Life: Simulations Meets Experiment”
- Place of Presentation
  香港・中国
- Year and Date
  2016-05-23
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 柔らかいタンパク質の分子機能理解と設計2016
- Author(s)
  林　重彦
- Organizer
  第10回分子科学討論会
- Place of Presentation
  神戸・兵庫
- Year and Date
  2016-09-13
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2016
- Author(s)
  Shigehiko Hayashi
- Organizer
  Japan-France-Spain Joint-Symposium on Theoretical and Computational Science of Complex Systems
- Place of Presentation
  ソウル・韓国
- Year and Date
  2016-09-21
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H04776
[Presentation] Atomistic Understanding and Design of Microbial Opsin-based Optogenetics Tools2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  Albany 2015: Conversation 19
- Place of Presentation
  Albany, USA
- Year and Date
  2015-06-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem2015 Symposium “Interplay between Chemistry and Dynamics in Biomolecular Machines”
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  IUPAC-2015 45th World Chemistry Congress
- Place of Presentation
  釜山・韓国
- Year and Date
  2015-08-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Understanding and designing color variants of retinal biding proteins by molecular simulations2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem2015 Symposium “Chemistry and Applications of Retinal Proteins: From Microbes to Humans”
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] タンパク質の pKa 制御とプロトン能動輸送の分子機構2015
- Author(s)
  林　重彦
- Organizer
  分子研研究会「膜タンパク質内部のプロトン透過を考える」
- Place of Presentation
  岡崎・愛知
- Year and Date
  2015-04-20
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Atomistic Understanding and Design of Microbial Opsin-based Optogenetics Tools2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  Albany 2015: Conversation 19
- Place of Presentation
  Albany, USA
- Year and Date
  2015-06-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] タンパク質の pKa 制御とプロトン能動輸送の分子機構2015
- Author(s)
  林　重彦
- Organizer
  分子研研究会「膜タンパク質内部のプロトン透過を考える」
- Place of Presentation
  岡崎・愛知
- Year and Date
  2015-04-20
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Understanding and designing color variants of retinal biding proteins by molecular simulations2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem2015 Symposium “Chemistry and Applications of Retinal Proteins: From Microbes to Humans”
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-18
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計2015
- Author(s)
  林　重彦
- Organizer
  第 12 回 AMO 討論会
- Place of Presentation
  東京
- Year and Date
  2015-06-19
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem2015 Symposium “Interplay between Chemistry and Dynamics in Biomolecular Machines”
- Place of Presentation
  Honolulu, USA
- Year and Date
  2015-12-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Role of Bound Water Molecules Inside Proteins in Their Functional Processes2015
- Author(s)
  林　重彦
- Organizer
  日本生物物理学会・シンポジウム “ポンプ、酵素、モーター、機能の鍵：pKa”
- Place of Presentation
  金沢・石川
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2015
- Author(s)
  Shigehiko Hayashi
- Organizer
  IUPAC-2015 45th World Chemistry Congress
- Place of Presentation
  釜山・韓国
- Year and Date
  2015-08-09
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計2015
- Author(s)
  林　重彦
- Organizer
  第 12 回 AMO 討論会
- Place of Presentation
  東京
- Year and Date
  2015-06-19
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Role of Bound Water Molecules Inside Proteins in Their Functional Processes2015
- Author(s)
  林　重彦
- Organizer
  日本生物物理学会・シンポジウム “ポンプ、酵素、モーター、機能の鍵：pKa”
- Place of Presentation
  金沢・石川
- Year and Date
  2015-09-13
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2014
- Author(s)
  Shigehiko Hayashi
- Organizer
  CRC-EC Joint Symposium on Chemical Theory on Complex System
- Place of Presentation
  Atlanta, USA
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計2014
- Author(s)
  林　重彦
- Organizer
  自然科学研究機構計算科学研究センタースーパーコンピュータワークショップ 2014「計算化学の最新の成果と展開」
- Place of Presentation
  岡崎・愛知
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計2014
- Author(s)
  林　重彦
- Organizer
  自然科学研究機構計算科学研究センタースーパーコンピュータワークショップ 2014「計算化学の最新の成果と展開」
- Place of Presentation
  岡崎・愛知
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2014
- Author(s)
  Shigehiko Hayashi
- Organizer
  CRC-EC Joint Symposium on Chemical Theory on Complex System
- Place of Presentation
  Atlanta, USA
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 酵素機能における分子の柔らかさの役割2014
- Author(s)
  林　重彦
- Organizer
  日本化学会第 94 春季年会中長期テーマシンポジウム「複雑系のための分子科学－理論研究によるアプローチ」
- Place of Presentation
  名古屋・愛知
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 酵素機能における分子の柔らかさの役割2014
- Author(s)
  林　重彦
- Organizer
  日本化学会第 94 春季年会中長期テーマシンポジウム「複雑系のための分子科学－理論研究によるアプローチ」
- Place of Presentation
  名古屋・愛知
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2013
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on “Protein Dynamics”
- Place of Presentation
  Telluride, USA
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] ハイブリッド分子シミュレーションでみる酵素の活性と柔らかさ2013
- Author(s)
  林　重彦
- Organizer
  第 13 回蛋白質科学会ワークショップ「計算科学と計測科学の協働により明らかになる蛋白質構造ダイナミクスの現状と将来
- Place of Presentation
  鳥取
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 光受容タンパク質の光吸収・蛍光スペクトルの理論的理解と合理的制御2013
- Author(s)
  林　重彦
- Organizer
  蛋白研セミナー「光の、光による、光のための蛋白質科学」
- Place of Presentation
  吹田・大阪
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2013
- Author(s)
  Shigehiko Hayashi
- Organizer
  Fifth Korea-Japan Seminars on Biomolecular Sciences: Experiments and Simulations
- Place of Presentation
  High 1 resort, Korea
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2013
- Author(s)
  Shigehiko Hayashi
- Organizer
  3rd International Conference on Molecular Simulations
- Place of Presentation
  神戸・兵庫
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2013
- Author(s)
  Shigehiko Hayashi
- Organizer
  Fifth Korea-Japan Seminars on Biomolecular Sciences: Experiments and Simulations
- Place of Presentation
  High 1 resort, Korea
- Year and Date
  2013-02-24
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] 分子シミュレーションから見た酵素の活性と柔らかさ2013
- Author(s)
  林重彦
- Organizer
  日本化学会第 93 春季年会中長期テーマシンポジウム「複雑系のための分子科学－複雑さと柔らかさ」
- Place of Presentation
  草津・滋賀
- Invited
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis2013
- Author(s)
  Shigehiko Hayashi
- Organizer
  3rd International Conference on Molecular Simulations
- Place of Presentation
  神戸・兵庫
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 分子シミュレーションから見た酵素の活性と柔らかさ2013
- Author(s)
  林重彦
- Organizer
  日本化学会第93春季年会中長期テーマシンポジウム「複雑系のための分子科学-複雑さと柔らかさ」
- Place of Presentation
  草津・滋賀
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] 分子シミュレーションから見た酵素の活性と柔らかさ2013
- Author(s)
  林重彦
- Organizer
  日本化学会第 93 春季年会中長期テーマシンポジウム「複雑系のための分子科学－複雑さと柔らかさ」
- Place of Presentation
  草津・滋賀
- Year and Date
  2013-03-22
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2012
- Author(s)
  Shigehiko Hayashi
- Organizer
  14th International Congress of Quantum Chemistry
- Place of Presentation
  Boulder, USA
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2012
- Author(s)
  Shigehiko Hayashi
- Organizer
  14th International Congress of Quantum Chemistry
- Place of Presentation
  Boulder, USA
- Year and Date
  2012-06-25
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2012
- Author(s)
  林重彦
- Organizer
  WIAS Top Runners’ Lecture Collection of Science「物質化学におけるコンピュータ利用の最前線」
- Place of Presentation
  早稲田・東京
- Invited
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2012
- Author(s)
  Shigehiko Hayashi
- Organizer
  Fifth International Symposium on Atomically Controlled Fabrication Technology
- Place of Presentation
  大阪
- Year and Date
  2012-10-22
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2012
- Author(s)
  林重彦
- Organizer
  WIAS Top Runners’ Lecture Collection of Science「物質化学におけるコンピュータ利用の最前線」
- Place of Presentation
  早稲田・東京
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] 「理論解析」の観点から2012
- Author(s)
  林重彦
- Organizer
  第4回光操作研究会「動作原理の理解と行動制御への応用」
- Place of Presentation
  岡崎・愛知
- Year and Date
  2012-09-27
- Invited
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] 「理論解析」の観点から2012
- Author(s)
  林重彦
- Organizer
  第4回光操作研究会「動作原理の理解と行動制御への応用」
- Place of Presentation
  岡崎・愛知
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2012
- Author(s)
  林重彦
- Organizer
  「水を主役としたATPエネルギー変換」第4回全体会議
- Place of Presentation
  宮城・仙台
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2012
- Author(s)
  林重彦
- Organizer
  WIAS Top Runners' Lecture Collection of Science「物質化学におけるコンピュータ利用の最前線」
- Place of Presentation
  早稲田・東
- Year and Date
  2012-11-20
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2012
- Author(s)
  Shigehiko Hayashi
- Organizer
  Fifth International Symposium on Atomically Controlled Fabrication Technology
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Chemicalreaction dynamics in solution and enzymes: A tribute to the memory of Professor Shigeki Kato2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  The fifth Asian Pacific Conference of Theoretical and Computational Chemistry
- Place of Presentation
  Rotorua, New Zealand
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] 生体機能の分子シミュレーション2011
- Author(s)
  林重彦
- Organizer
  文部科学省「革新的ハイパフォーマンス・コンピューティング・インフラ(HPCI)の構築」次世代スーパーコンピュータ戦略分野2「新物質・エネルギー創成」計算物質科学イニシアティブ(CMSI)計算分子科学研究拠点第1回研究会
- Place of Presentation
  愛知・岡崎
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  2011 Karen Japan Symposhim on Molecular Science "New Visions for Spectroscopy & Computation : Temporal and Spatial Advantures of Molecular Sciences"
- Place of Presentation
  釜山(韓国)
- Year and Date
  2011-07-06
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  2011 Korea Japan Symposium on Molecular Science "New Visions for Spectroscopy & Computation : Temporal and Spatial Adventures of Molecular Science"
- Place of Presentation
  釜山(韓国)
- Year and Date
  2011-07-06
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] Molecular mechanisms of enzymatic catalysis in F1-ATPase and a-amylase2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  WATOC 2011
- Place of Presentation
  Santiago de Compostela (Spain)
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2011
- Author(s)
  林重彦
- Organizer
  大阪大学蛋白質研究所セミナー「蛋白質科学の未来を語る-実験・理論研究者の対話-」
- Place of Presentation
  吹田(大阪)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2011
- Author(s)
  林重彦
- Organizer
  大阪大学蛋白質研究所セミナー「蛋白質科学の未来を語る-実験・理論研究者の対話-」
- Place of Presentation
  吹田(大阪)
- Year and Date
  2011-11-21
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] 新規微生物型ロドプシン(MR)から観る光駆動イオンポンプから光センサーへの分子進化2011
- Author(s)
  須藤雄気, 井原邦夫, 小林詩織, 鈴木大介, 入枝泰樹, 菊川峰志, 神取秀樹, 本間道夫
- Organizer
  第84回・日本生化学会年会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23657100
[Presentation] Molecular mechanisms of enzymatic catalysis in F1-ATPase and □-amylase2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  WATOC 2011
- Place of Presentation
  Santiago de Compostela, Spain
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] ハイブリッド分子シミュレーションで探る酵素反応の分子機構2011
- Author(s)
  林重彦
- Organizer
  分子研研究会「実験と理論による高次分子システムの機能発現の分子論的理解」
- Place of Presentation
  愛知・岡崎
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Molecular mechanism of enzymatic reaction studied by the QM/MM reweighting free energy SCF method2011
- Author(s)
  Shigehiko Hayashi, Takahiro Kosugi
- Organizer
  日本生物物理学会・シンポジウム"New approaches for probing biomolecular fluctuations"
- Place of Presentation
  姫路(兵庫)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  Fukui International Symposium for Theoretical Chemistry
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on "Riss of the Machines : Intergration of expertment, simulation and theory for a mechanistic understanding of biomolecular machines"
- Place of Presentation
  Telluride (USA)
- Year and Date
  2011-08-09
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on "Rise of the Machines: Integration of experiment, simulationand theory for a mechanisticunderstanding of biomolecular machines"
- Place of Presentation
  Telluride, Colorado
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] ハイブリッド分子シミュレーションで探る酵素活性の分子機構2011
- Author(s)
  林重彦
- Organizer
  大阪大学蛋白質研究所セミナー「蛋白質科学の未来を語る-実験・理論研究者の対話 -」
- Place of Presentation
  大阪・豊中
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on "Rise of the Machines : Integration of experiment, simulation and theory for a mechanistic understanding of biomolecular machines"
- Place of Presentation
  Telluride (USA)
- Year and Date
  2011-08-09
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] Molecular mechanisms of enzymatic catalysis in F1-ATPase and a-amylase2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  WATOC 2011
- Place of Presentation
  Santiago de Compostela (Spain)
- Year and Date
  2011-07-21
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  IMS Symposium on "Recent Developments of Spectroscopy and Spatial and Temporal Hierarchical Structures in Molecular Science"
- Place of Presentation
  愛知・岡崎
- Year and Date
  2011-10-18
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Molecular mechanism of enzymatic reaction studied by the QM/MM reweighting free energy SCF method2011
- Author(s)
  Shigehiko Hayashi, Takahiro Kosugi
- Organizer
  日本生物物理学会・シンポジウム"New approaches for probing biomolecular fluctuations"
- Place of Presentation
  姫路(兵庫)
- Year and Date
  2011-09-17
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] Hybrid molecular simulations toward understanding enzymatic catalysis2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  2011 Korea Japan Symposium on Molecular Science "New Visions for Spectroscopy & Computation: Temporal and Spatial Adventures of Molecular Science"
- Place of Presentation
  韓国・釜山
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Fukui International Symposium for Theoretical Chemistry2011
- Author(s)
  Shigehiko Hayashi
- Organizer
  Fukui International Symposium for Theoretical Chemistry
- Place of Presentation
  京都
- Year and Date
  2011-09-01
- Data Source
  KAKENHI-PUBLICLY-23107717
[Presentation] Molecular mechanism of enzymatic reaction studied by the QM/MM reweighting free energy SCF method2011
- Author(s)
  Shigehiko Hayashi and Takahiro Koaugi
- Organizer
  日本生物物理学会・シンポジウム "New approaches for probing biomolecular fluctuations"
- Place of Presentation
  兵庫・姫路
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Chemical reactions and molecular dynamics in functional processes of motor and photoreceptor proteins2010
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem 2010 Symposium "Computational Quantum Chemistry : Theory and Interactions with Experiment"
- Place of Presentation
  Honolulu(米国)
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Chemical reactions and molecular dynamics in functional processes of motor and photoreceptor proteins2010
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem 2010 Symposium "Computational Quantum Chemistry: Theory and Interactions with Experiment"
- Place of Presentation
  Honolulu, USA
- Data Source
  KAKENHI-PROJECT-22370058
[Presentation] Chemical reactions and molecular dynamics in functional processes of motor and photoreceptor proteins2010
- Author(s)
  Shigehiko Hayashi
- Organizer
  Pacifichem 2010 Symposium "Computational Quantum Chemistry : Theory and Interactions with Experiment"
- Place of Presentation
  Honolulu(米国)(招待講演)
- Year and Date
  2010-12-19
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical reactions and molecular dynamics in functional processes of motor and photoreceptor proteins2010
- Author(s)
  S.Hayashi
- Organizer
  Pacifichem 2010 Symposium "Computational Quantum Chemistry: Theory and Interactions with Experiment"
- Place of Presentation
  Honolulu(米国)
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] 分子シミュレーションによるタンパク質機能の分子機構の解明2010
- Author(s)
  林重彦
- Organizer
  新学術領域研究「高次π 空間の創発と機能開発」第三回公開シンポジウム
- Place of Presentation
  分子科学研究所
- Year and Date
  2010-03-15
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Photochemical Reaction Dynamics of Retinal Proteins2010
- Author(s)
  Shigehiko Hayashi
- Organizer
  69th Okazaki Conference on "New Frontier in Quantum Chemical Dynamics"
- Place of Presentation
  分子科学研究所
- Year and Date
  2010-02-22
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] ロドプシンのエネルギー変換と情報変換:理論的解析の現状と展望2009
- Author(s)
  林重彦
- Organizer
  第三回分子科学会シンポジウム「ロドプシンのエネルギー変換と情報変換」
- Place of Presentation
  東京工業大学
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] タンパク質内化学反応の分子機構に関する理論的研究2009
- Author(s)
  林重彦
- Organizer
  日本化学会東北支部・物理化学コロキウム
- Place of Presentation
  日本大学
- Year and Date
  2009-09-20
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] タンパク質中の化学反応経路2009
- Author(s)
  林重彦
- Organizer
  シンポジウム「化学反応経路探索のニューフロンティア」
- Place of Presentation
  豊田理化学研究所
- Year and Date
  2009-09-25
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions and Molecular Dynamics in Functional Processes of Motor and Photoreceptor Proteins2009
- Author(s)
  S.Hayashi
- Organizer
  2nd Japan-Korea Seminar on Biomolecular Sciences-Experiments and Simulations
- Place of Presentation
  名古屋大学
- Year and Date
  2009-12-23
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Simulations on Enzymatic Reactions and Structural Dynamics of Fl-ATPase2009
- Author(s)
  Shigehiko Hayashi, Myco Umemura, Yuko Ito, Mitsunori Ikeguchi
- Organizer
  International Symposium on "Innovative Nanoscience of Supermolecular Motor Proteins Working in Biomembrane"
- Place of Presentation
  京都大学
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Dynamics in Functional Processes of Photosensitive Proteins2009
- Author(s)
  Shigehiko Hayashi
- Organizer
  Japan-Korea Symposium on Molecular Science 2009 "Chemical Dynamics in Materials and Biological Molecular Sciences"
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Mechanisms of Enzymatic Activities in Motor and Photoreceptor Proteins2009
- Author(s)
  S.Hayashi
- Organizer
  CREST International Symposium on Theory and Simulations of Complex Molecular Systems
- Place of Presentation
  福井謙一記念研究センター
- Year and Date
  2009-07-21
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Simulations on Enzymatic Reactions and Structural Dynamics of F1-ATPase2009
- Author(s)
  S.Hayashi, M.Umemura, Y.Ito, M.Ikeguchi
- Organizer
  International Symposium on "Innovative Nanoscience of Supermolecular Motor Proteins Working in Biomembrane"
- Place of Presentation
  京都大学
- Year and Date
  2009-09-09
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Dynamics in Functional Processes of Photosensitive Proteins2009
- Author(s)
  S.Hayashi
- Organizer
  Japan-Korea Symposium on Molecular Science 2009 "Chemical Dynamics in Materials and Biological
- Place of Presentation
  淡路夢舞台国際会議場
- Year and Date
  2009-07-13
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Dynamics in Functional Processes of Photoreceptor Proteins2009
- Author(s)
  Shigehiko Hayashi
- Organizer
  International Symposium on "Reaction Dynamics of Many-Body Chemical Systems"
- Place of Presentation
  京都大学
- Year and Date
  2009-06-22
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] 生体機能の分子理論2009
- Author(s)
  林重彦
- Organizer
  実在系の分子理論・研究交流会
- Place of Presentation
  金沢文化ホール
- Year and Date
  2009-09-04
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Molecular Mechanism of ATP hydrolysis reaction in F1-ATPase molecular motor2008
- Author(s)
  A.R.Shaikh, Y.Ito, M.Ikeguchi, H.Ueno, H.Noji, S.Hayashi
- Organizer
  日本生物物理学会第46回年会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions in Photoreceptor and Motor Proteins Studied by hybrid QM/MM Simulations2008
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on "Protein Dynamics"
- Place of Presentation
  Telluride , Colorado (USA)
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] ハイブリッド分子シミュレーションで探るF1-ATPase分子モーターの化学-力学エネルギー変換機構2008
- Author(s)
  林重彦
- Organizer
  生物物理学会シンポジウム「F1-ATPase 分子モーターの分子機構」
- Place of Presentation
  神奈川・横浜
- Year and Date
  2008-12-22
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] ハイブリッド分子シミュレーションで探るF1-ATPase分子モーターの化学-力学エネルギー変換機構2008
- Author(s)
  林重彦
- Organizer
  生物物理学会シンポジウム「F1-ATPase分子モーターの分子機構」
- Place of Presentation
  神奈川・横浜
- Year and Date
  2008-12-22
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions in Photoreceptor and Motor Proteins Studied by hybrid QM/MM Simulations2007
- Author(s)
  S.Hayashi
- Organizer
  I2CAM Exploratory Workshop "Quantum Dynamics and Biomolecular Function"
- Place of Presentation
  Yeppoon, Australia.
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions in Photoreceptor and Motor Proteins Studied by hybrid QM/MM Simulations2007
- Author(s)
  Shigehiko Hayashi
- Organizer
  Telluride Science Research Center Workshop on "Protein Dynamics"
- Place of Presentation
  Telluride, Colorado
- Year and Date
  2007-08-01
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions in Photoreceptor and Motor Proteins Studied by hybrid QM/MM Simulations2007
- Author(s)
  Shigehiko Hayashi
- Organizer
  I2CAM Exploratory Workshop "Quantum Dynamics and Biomolecular Function"
- Place of Presentation
  Yeppoon, Australia
- Year and Date
  2007-04-12
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions in Photoreceptor and Motor Proteins Studied by hybrid QM/MM Simulations2007
- Author(s)
  S.Hayashi
- Organizer
  Telluride Science Research Center Workshop on "Protein Dynamics"
- Place of Presentation
  Telluride, Colorado.
- Year and Date
  2007-08-01
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] 分子シミュレーションで探るタンパク質の光受容と機能2007
- Author(s)
  林重彦
- Organizer
  特定領域「実在系の分子理論」A02・A03班合同研究会「実験と理論のインタープレイ」
- Place of Presentation
  東京・早稲田
- Year and Date
  2007-11-16
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] 膜超分子の分子シミュレーション2006
- Author(s)
  池口満徳、林重彦
- Organizer
  日本分子生物学会2006フォーラム「分子生物学の未来」シンポジウム「生命科学の革新的ナノバイオロジー」
- Place of Presentation
  愛知・名古屋
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Chemical Reactions in Photoreceptor and Motor Proteins Studied by hybrid QM/MM Simulations2006
- Author(s)
  S.Hayashi
- Organizer
  Discussion on "Theory and Simulation of biomolecular nano-machines"
- Place of Presentation
  兵庫・舞子
- Data Source
  KAKENHI-PLANNED-18074004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis
- Author(s)
  Shigehiko Hayashi
- Organizer
  Les Houches-TSRC Workshop on Protein Dynamics
- Place of Presentation
  Les Houches, France
- Year and Date
  2014-05-18 – 2014-05-23
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Understanding and Designing Color Variants of Retinal Biding Proteins by Molecular Simulations
- Author(s)
  Shigehiko Hayashi
- Organizer
  16th International Conference on Retinal Proteins
- Place of Presentation
  長浜・滋賀
- Year and Date
  2014-10-05 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis
- Author(s)
  Shigehiko Hayashi
- Organizer
  Les Houches-TSRC Workshop on Protein Dynamics
- Place of Presentation
  Les Houches, France
- Year and Date
  2014-05-18 – 2014-05-23
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計
- Author(s)
  林　重彦
- Organizer
  理研シンポジウム「生体分子系量子化学計算の最前線」
- Place of Presentation
  和光・埼玉
- Year and Date
  2015-01-22 – 2015-01-23
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 柔らかいタンパク質の分子機能の理解と設計
- Author(s)
  林　重彦
- Organizer
  第 14 回蛋白質科学会年会　公募型シンポジウム
- Place of Presentation
  横浜・神奈川
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Understanding and Designing Color Variants of Retinal Biding Proteins by Molecular Simulations
- Author(s)
  Shigehiko Hayashi
- Organizer
  16th International Conference on Retinal Proteins
- Place of Presentation
  長浜・滋賀
- Year and Date
  2014-10-05 – 2014-10-10
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis
- Author(s)
  Shigehiko Hayashi
- Organizer
  4th Indo-German Meeting on Modeling of Chemical and Biological Reactivity (MCBR4)
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2015-02-23 – 2015-02-25
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計
- Author(s)
  林　重彦
- Organizer
  CBI 学会 2014 年大会　プレナリーレクチャー
- Place of Presentation
  東京
- Year and Date
  2014-10-28 – 2014-10-30
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] 柔らかいタンパク質の分子機能の理解と設計
- Author(s)
  林　重彦
- Organizer
  理研シンポジウム「生体分子系量子化学計算の最前線」
- Place of Presentation
  和光・埼玉
- Year and Date
  2015-01-22 – 2015-01-23
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計
- Author(s)
  林　重彦
- Organizer
  CBI 学会 2014 年大会　プレナリーレクチャー
- Place of Presentation
  東京
- Year and Date
  2014-10-28 – 2014-10-30
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] Catalytic mechanism of NTPases
- Author(s)
  Shigehiko Hayashi
- Organizer
  Tokyo ATPase Workshop
- Place of Presentation
  東京
- Year and Date
  2014-06-02 – 2014-06-03
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Crucial Role of Protein Flexibility in Enzymatic Catalysis
- Author(s)
  Shigehiko Hayashi
- Organizer
  4th Indo-German Meeting on Modeling of Chemical and Biological Reactivity (MCBR4)
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2015-02-23 – 2015-02-25
- Invited
- Data Source
  KAKENHI-PLANNED-25104004
[Presentation] Catalytic mechanism of NTPases
- Author(s)
  Shigehiko Hayashi
- Organizer
  Tokyo ATPase Workshop
- Place of Presentation
  東京
- Year and Date
  2014-06-02 – 2014-06-03
- Invited
- Data Source
  KAKENHI-PROJECT-25291034
[Presentation] 柔らかいタンパク質の分子機能の理解と設計
- Author(s)
  林　重彦
- Organizer
  第 14 回蛋白質科学会年会　公募型シンポジウム
- Place of Presentation
  横浜・神奈川
- Year and Date
  2014-06-25 – 2014-06-27
- Invited
- Data Source
  KAKENHI-PLANNED-25104004

1. IKEGUCHI Mitsunori (60261955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. NOJI Hiroyuki (00343111)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. HONMA Michio (50209342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. HISABORI Toru (40181094)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NISHIZAKA Takayuki (40359112)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. TAKEUCHI Shoji (90343110)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. IMADA Katsumi (40346143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SUDO Yuki (10452202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
9. TAHARA Tahei (60217164)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MORITA Akihiro (70252418)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. TAKAHASHI Satoshi (30283641)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. MURAHASHI Tetsuro (40314380)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NAKANISHI Takashi (40391221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 神取秀樹 (70202033)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
15. 水谷泰久 (60270469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 北尾彰朗 (30252422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 藤井正明 (60181319)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. INUTSUKA Ayumu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. ISHITANI Ryuichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
20. IINO Ryota

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
21. INOUE Keiichi

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
22. TSUKAMOTO Takashi

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
23. SAITO Shinji

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 山中章弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 児嶋長次郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 加藤重樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
27. 渡邉朋信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
28. 渡邉力也

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. CHENG CHENG

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
30. 吉田紀生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
31. 濡木理

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
32. 林久美子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
33. REISSIG Louisa

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
34. 高木新

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
35. 井原邦夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
36. 宮内正二

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
37. 吉沢道人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
38. 齊藤真司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
39. 東雅大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
40. 高田彰二

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Shigehiko 林 重彦

HAYASHI Shigehiko 林 重彦

Research Projects

Research Products

Co-Researchers

Theoretical Study on molecular mechanisms of functional processes of biological moleculesPrincipal InvestigatorOngoing

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Theoretical determination of protonation states of the manganese cluster in photosystem IIPrincipal InvestigatorOngoing

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Theoretical Study of Molecular functions of ProteinsPrincipal Investigator

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Support for International Activities of Studying the Function of Soft Molecular Systems by Concerted Use of Theory and Experiment

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Theoretical Analysis and Rational Design of Catalytic Activity of Flexible MoleculesPrincipal Investigator

Principal Investigator

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Theoretical study on molecular mechanisms of protein functionsPrincipal Investigator

Principal Investigator

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タンパク質機能におけるｐＫａ制御の分子機構Principal Investigator

Principal Investigator

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Investigation of color tuning mechanism in rhodopsins and production of multi-colored pigments

Principal Investigator

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Theoretical study of molecular mechanism of protein functionsPrincipal Investigator

Principal Investigator

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Molecular mechanism of chemical-mechanical energy conversion of F1 molecular motor studied by molecular simulationsPrincipal Investigator

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Innovative nanoscience of supermolecular motor proteins working in biomembranes

Principal Investigator

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[Book] 岩波講座計算科学第 4 巻 計算と生命, 第 3.3 章2012

Author(s)

Publisher

Data Source

[Book] タンパク質の生物学的機能と化学反応, 岩波講座計算科学第4 巻 計算と生命, 第3.3 章2012

Author(s)

Data Source

[Book] 酵素反応と生体分子機能の分子シミュレーション. CSJ カレントレヴュー・巨大分子系の計算化学, 08, 第17 章2012

Author(s)

Data Source

Hayashi Shigehiko 林重彦

HAYASHI Shigehiko 林重彦

[Book] 岩波講座計算科学第 4 巻　計算と生命, 第 3.3 章2012

[Book] タンパク質の生物学的機能と化学反応, 岩波講座計算科学第4 巻計算と生命, 第3.3 章2012

[Book] 岩波講座計算科学第 4 巻　計算と生命, 第 3.3 章2012