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Shinzawa Koei  新澤 康英

ORCIDConnect your ORCID iD *help
… Alternative Names

新澤 康英  シンザワ コウエイ

新沢 康英  シンザワ コウエイ

SHINZAWA Koei  新沢 康英

新沢 康永  シンザワ コウエイ

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Researcher Number 70403186
Other IDs
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help 2025: 大阪大学, 大学院医学系研究科, 助教
2023: 大阪大学, 大学院医学系研究科, 助教
2020 – 2021: 大阪大学, 医学系研究科, 助教
2015: 大阪大学, 医学(系)研究科(研究院), 助教
2013: 大阪大学, 医学(系)研究科(研究院), 助教 … More
2012: 大阪大学, 大学院・医学系研究科, 助教
2011: 大阪大学, 医学系・研究科, 助教
2007 – 2011: 大阪大学, 医学系研究科, 助教 Less
Review Section/Research Field
Principal Investigator
Basic Section 50010:Tumor biology-related / Pathological medical chemistry
Except Principal Investigator
Neurosurgery
Keywords
Principal Investigator
細胞増殖 / モデルマウス / ピリミジン代謝 / 癌化 / メタボローム解析 / メラノサイト / マウスモデル / ピリミジン合成 / アンチセンス核酸 / GREB1 … More / 悪性黒色腫 / パーキンソン病 / phospholipase A2 / ノックアウトマウス / 脳神経疾患 / ホスホリパーゼA2 / ミトコンドリア / 疾患モデルマウス / スフェロイド / 神経軸索ジストロフィー … More
Except Principal Investigator
ニューロン / シュワン細胞 / オリゴデンドロサイト / オルファクトリースフィア / GABAニューロン / オリゴデンドロサイト前駆細胞 / 神経幹細胞 / 嗅粘膜 / 虚血 / 細胞交代 / ミトコンドリア / 個体発生 / マウス / 形態形成 / オートファジー / プログラム細胞死 / ネクローシス / アポトーシス / 細胞死 Less
  • Research Projects

    (5 results)
  • Research Products

    (28 results)
  • Co-Researchers

    (13 People)
  •  新規人工受容体技術を用いた腫瘍内在シグナルと腫瘍免疫との関係解明Principal Investigator

    • Principal Investigator
      新澤 康英
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      The University of Osaka
  •  Functional analysis of novel genes regulating malignant melanoma and their application to cancer therapyPrincipal Investigator

    • Principal Investigator
      Shinzawa Koei
    • Project Period (FY)
      2020 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50010:Tumor biology-related
    • Research Institution
      Osaka University
  •  Development of regenerative medicine by oligodendrocyte and schwann precursor cells

    • Principal Investigator
      Ohnishi Yuichiro
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurosurgery
    • Research Institution
      Osaka University
  •  Study of the pathomechanism of neuroaxonal distrophy using iPLA2beta-deficient mousePrincipal Investigator

    • Principal Investigator
      KOEI Shinzawa
    • Project Period (FY)
      2010 – 2011
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Osaka University
  •  Integrated study of cell death: Biology focusing on multiple mechanisms of mammalian cell death

    • Principal Investigator
      TSUJIMOTO Yoshihide
    • Project Period (FY)
      2007 – 2012
    • Research Category
      Grant-in-Aid for Creative Scientific Research
    • Research Institution
      Osaka University

All 2023 2021 2020 2015 2013 2012 2011 2010 2009 2008 2007

All Journal Article Presentation

  • [Journal Article] GREB1 isoform 4 is specifically transcribed by MITF and required for melanoma proliferation2023

    • Author(s)
      Shinzawa Koei、Matsumoto Shinji、Sada Ryota、Harada Akikazu、Saitoh Kaori、Kato Keiko、Ikeda Satsuki、Hirayama Akiyoshi、Yokoi Kazunori、Tanemura Atsushi、Nimura Keisuke、Ikawa Masahito、Soga Tomoyoshi、Kikuchi Akira
    • Journal Title

      Oncogene

      Volume: 42 Issue: 42 Pages: 3142-3156

    • DOI

      10.1038/s41388-023-02803-6

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-21K19408, KAKENHI-PROJECT-23K18240, KAKENHI-PROJECT-20K07571, KAKENHI-PLANNED-21H05160, KAKENHI-PROJECT-23K23865, KAKENHI-ORGANIZER-23H04939, KAKENHI-ORGANIZER-21H05158, KAKENHI-PROJECT-22H04922
  • [Journal Article] Isolation of human adult olfactory sphere cells as a cell source of neural progenitors.2015

    • Author(s)
      Ohnishi Y1, Iwatsuki K2, Ishihara M2, Shikina T3, Shinzawa K4, Moriwaki T2, Ninomiya K2, Ohkawa T2, Umegaki M2, Kishima H2, Yoshimine T2.
    • Journal Title

      Stem Cell Research

      Volume: 15(1) Issue: 1 Pages: 23-29

    • DOI

      10.1016/j.scr.2015.04.006

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-26462205, KAKENHI-PROJECT-15K21134, KAKENHI-PROJECT-25462215
  • [Journal Article] Olfactory sphere cells are a cell source for γ-aminobutyric acid-producing neurons.2015

    • Author(s)
      Ohnishi YI, Maruo T, Shinzawa K, Iwatsuki K, Moriwaki T, Oshino S, Kishima H, YoshimineT
    • Journal Title

      J Neurosci Res. 2

      Volume: 93 Issue: 8 Pages: 1293-1304

    • DOI

      10.1002/jnr.23585

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-26462208, KAKENHI-PROJECT-25462215
  • [Journal Article] Adult olfactory sphere cells are a source of oligodendrocyte and Schwann cell progenitors.2013

    • Author(s)
      Ohnishi Y, Iwatsuki K et al.
    • Journal Title

      Stem Cell Research

      Volume: 11 Issue: 3 Pages: 1178-1190

    • DOI

      10.1016/j.scr.2013.08.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23592124, KAKENHI-PROJECT-24791498, KAKENHI-PROJECT-25462215
  • [Journal Article] Analysis of two major intracellular phospholipases A(2)(PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts2011

    • Author(s)
      Ueno N, Taketomi Y, Yamamoto K, Hirabayashi T, Kamei D, Kita Y, Shimizu T, Shinzawa K, Tsujimoto Y, Ikeda K, Taguchi R, Murakami M
    • Journal Title

      J Biol Chem

      Volume: 286 Pages: 37249-63

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790314
  • [Journal Article] Insufficient remodeling of membranes of mitochondria and axon terminals causes neuroaxonal dystrophy in calcium-independent phospholipase A2β deficiency2011

    • Author(s)
      Beck, G., Sugiura, Y., Shinzawa, K., Kato, S., Setou, M., Tsujimoto, Y., Sakoda, S., and Sumi-Akamaru, H
    • Journal Title

      J. Neurosci.

      Volume: 31 Pages: 11411-11420

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Analysis of two major intracellular phospholipase A2s in mast cells reveals crucial contribution of cPLA2{alpha}, not iPLA2{beta}, to lipid mobilization in proximal mast cells and distal fibroblasts2011

    • Author(s)
      Ueno, N., Taketomi, Y., Yamamoto, K., Hirabayashi, T., Kamei, D., Kita, Y., Shimizu, T., Shinzawa, K., Tsujimoto, Y., Ikeda, K., Taguchi, R., and Murakami, M.
    • Journal Title

      J Biol Chem.

      Volume: 286 Pages: 37249-37263

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Neuroaxonal dystrophy in calcium-independent phospholipase A2βdeficiency results from insufficient remodeling and degeneration of mitochondrial and presynaptic membranes2011

    • Author(s)
      Beck G, Sugiura Y, Shinzawa K, Kato S, Setou M, Tsujimoto Y, Sakoda S, Sumi-Akamaru H.
    • Journal Title

      J Neurosci

      Volume: 31 Pages: 11411-20

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22790314
  • [Journal Article] Noxa is necessary for hydrogen peroxide-induced caspase-dependent cell death.2010

    • Author(s)
      Aikawa, T., Shinzawa, K., Tanaka, N. and Tsujimoto, Y.
    • Journal Title

      FEBS Letter

      Volume: 584 Pages: 681-688

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Essential role of p38 MAPK in caspase-independent, iPLA2-dependent cell death under hypoxia/low glucose conditions.2009

    • Author(s)
      Aoto, M., Shinzawa, K., Suzuki, Y., Ohkubo, N., Mitsuda, N. and Tsujimoto, Y.
    • Journal Title

      FEBS letter

      Volume: 583 Pages: 1611-1618

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Neuroaxonal dystrophy caused by group VIA phospholipase A_2 deficiency in mice: a model of human neurodegenerative disease.2008

    • Author(s)
      Shinzawa, K., Sumi, H., Ikawa, M., Matsuoka, Y., Okabe, M., Sakoda, S., Tsujimoto, Y.
    • Journal Title

      J. Neuroscience (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes2008

    • Author(s)
      Han, M. S., Park, S. Y., Shinzawa, K., Kim, S., Chung, K. W., Lee, J. H., Kwon, C. H., Lee, K. W., Lee, J. H., Park, C. K., Chung, W. J., Hwang, J. S., Yan, J. J., Song, D. K., Tsujimoto, Y., Lee, M. S
    • Journal Title

      J. Lipid Res. 49

      Pages: 84-97

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Neuroaxonal dystrophy caused by group VIA phospholipase A2 deficiency in mice: a model of human neurodegenerative disease.2008

    • Author(s)
      Shinzawa, K., Sumi, H., Ikawa, M., Matsuoka, Y., Okabe, M., Sakoda, S. and Tsujimoto, Y.
    • Journal Title

      J. Neurosci.

      Volume: 28 Pages: 2212-2220

    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Journal Article] Neuroaxonal dystrophy caused by group VIA phospholipase A_2 deficiency in mice : a model of human neurodegenerative disease2008

    • Author(s)
      Shinzawa, K., Sumi, H., Ikawa, M., Matsuoka, Y., Okabe, M., Sakoda, S., Tsujimoto, Y.
    • Journal Title

      J.Neurosci. 28

      Pages: 2212-2220

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] GREB1 isoform 4の悪性黒色腫形成における役割と治療への応用2023

    • Author(s)
      新沢康英、松本真司、佐田遼太、原田昭和、種村篤、横井一範、二村圭祐、伊川正人、曽我朋義、菊池 章
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K07571
  • [Presentation] GREB1 isoform 4はピリミジン合成を介して悪性黒色腫細胞の増殖能を促進する2021

    • Author(s)
      新澤 康英, 松本 真司, 種村 篤, 横井 一範, 藤本 学, 二村 圭祐, 曽我 朋義, 菊池 章
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-20K07571
  • [Presentation] 悪性黒色腫におけるGREB1 isoform 4の発現機構解析とがん治療への応用2020

    • Author(s)
      新沢康英、 松本真司、種村篤、藤本学、菊池 章
    • Organizer
      第93回日本生化学会大会
    • Data Source
      KAKENHI-PROJECT-20K07571
  • [Presentation] アセトアミノフェンにより誘導される接着肝細胞の同期的な細胞死2012

    • Author(s)
      斎藤千恵子、新沢康英、辻本賀英
    • Organizer
      第35回日本分子生物学会年会
    • Place of Presentation
      福岡国際会議場
    • Year and Date
      2012-12-12
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] iPLA2beta欠損マウスは神経軸索ジストロフィーを発症する2010

    • Author(s)
      新沢康英、辻本賀英
    • Organizer
      第19回日本Cell Death学会年会
    • Place of Presentation
      愛知県産業労働会館
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] iPLA2beta欠損マウスは神経軸索ジストローフィーを発症する2010

    • Author(s)
      新沢康英
    • Organizer
      第19回日本Cell Death学会学術集会
    • Place of Presentation
      名古屋市 愛知県産業労働会館
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-22790314
  • [Presentation] iPLA2beta欠損マウスは神経軸索ジストロフィーを発症する2010

    • Author(s)
      新沢康英
    • Organizer
      第19回日本Cell Death学会学術集会
    • Place of Presentation
      名古屋
    • Year and Date
      2010-07-31
    • Data Source
      KAKENHI-PROJECT-22790314
  • [Presentation] The roles of Ca2+-indepenedent group VIA phospholipase A2 (iPLA2b) in hyopoxic death and neuroaxonal dystrophy2008

    • Author(s)
      Shinzawa, K., Sumi, H., Ikawa, M., Matsuoka, Y., Okabe. M., Sakoda, S., Tsujimoto, Y.
    • Organizer
      The 7^<th> International Cell Death Society Symposium Shanghai, China
    • Place of Presentation
      中国 上海
    • Year and Date
      2008-06-08
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] 酸化ストレス誘導性アポトーシスの解析2008

    • Author(s)
      相川知徳、新沢康英、辻本賀英
    • Organizer
      第31回日本分子生物学会年会
    • Place of Presentation
      神戸国際会議場
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] The roles of Ca2+-indepenedent group VIA phospholipase A2 (iPLA2β) in hyopoxic death and neuroaxonal dystrophy.2008

    • Author(s)
      新沢康英、隅 寿恵、松岡洋祐、佐古田三郎、辻本賀英
    • Organizer
      The 7th International Cell Death Society Symposium Shanghai, China
    • Place of Presentation
      上海(中国)
    • Year and Date
      2008-06-08
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] 酸化ストレス誘導性アポトーシスの解析2008

    • Author(s)
      相川知徳, 新沢康英, 辻本賀英
    • Organizer
      日本分子生物学会年会2008
    • Place of Presentation
      神戸
    • Year and Date
      2008-12-09
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] The roles of Ca2+-indepenedent group VIA phospholipase A2 (iPLA2b) in hyopoxic death and neuroaxonal dystrophy2008

    • Author(s)
      Shinzawa, K., Sumi, H., Ikawa, M., Matsuoka, Y., Okabe. M., Sakoda, S., Tsujimoto, Y.
    • Organizer
      The 7^<th> International Cell Death Society Symposium
    • Place of Presentation
      中国上海
    • Year and Date
      2008-06-08
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] ストレス刺激で誘導されるグローバルヒストン脱アセチル化機構2007

    • Author(s)
      新沢康英、相川知徳、辻本賀英
    • Organizer
      第30回日本分子生物学会年会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2007-12-18
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • [Presentation] ストレス刺激で誘導されるグローバルヒストン脱アセチル化機構2007

    • Author(s)
      新沢康英、相川知徳、辻本賀英
    • Organizer
      日本分子生物学会年会2007
    • Place of Presentation
      横浜
    • Year and Date
      2007-12-18
    • Data Source
      KAKENHI-PROJECT-19GS0316
  • 1.  TSUJIMOTO Yoshihide (70132735)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 2.  EGUCHI Yutaka (20243214)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  SHIBUYA Toshiharu (70448033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  HAMADA Yoshio (10132739)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Ohnishi Yuichiro (00533811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  Yoshimine Toshiki (00201046)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  Kishima Haruhiko (10332743)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  Iwatsuki Koichi (80346204)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 9.  恵口 豊 (20243206)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  ISHIHARA Masahiro
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  OSHINO Satoru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  辻本 貨英
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 17 results
  • 13.  二村 圭祐
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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