Hirano Yu 平野悠

… Alternative Names

HIRANO Yu 平野悠

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Researcher Number	70415735
Affiliation (Current)	2025: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員
Affiliation (based on the past Project Information) *help	2016 – 2023: 国立研究開発法人産業技術総合研究所, 生命工学領域, 主任研究員 2015 – 2016: 国立研究開発法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 2012 – 2014: 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 主任研究員 2011: 独立行政法人産業技術総合研究所, 生物プロセス研究部門, 研究員 2008 – 2009: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 研究員 2007: National Institute of Advanced Industrial Science and Technology, ゲノムファクトリー研究部門, 研究員 2006: 独立行政法人産業技術総合研究所, ゲノムファクトリー研究部門, 研究員
Review Section/Research Field	Principal Investigator Analytical chemistry / Basic Section 34020:Analytical chemistry-related Except Principal Investigator Drug development chemistry / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
Keywords	Principal Investigator SECM / 電気化学 / マイクロ電極 / 細胞 / 心筋細胞 / 一細胞分析 / 走査型電気化学顕微鏡 / バイオ関連機器 / 走査型プローブ顕微鏡 / ncRNA … More / 顕微鏡 / アンチセンス / microRNA / マイクロ・ナノ電極 / DNA / 酵素 / 生体分析 … More Except Principal Investigator 核酸 / miRNA / クロスリンク / RNA / 核酸医薬 / アンチセンス / 遺伝子 / オリゴヌクレオチド / microRNA / antisense / oligonucleotide therapy / oligonucleotide / siRNA Less

miRNA制御核酸の機能を細胞単位で解析する技術の開発Principal Investigator
- Principal Investigator
  
  平野悠
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 34020:Analytical chemistry-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Complex formation between RNA cleaving-enzyme and antisense and its application to regulation of long non-coding RNAs.
- Principal Investigator
  
  Yasuo Komatsu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of microbiosensor with DNA scaffolds for cell metabolic analysisPrincipal Investigator
- Principal Investigator
  
  Hirano Yu
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of anti-miRNA oligonucleotides on the basis of structure control.
- Principal Investigator
  
  Komatsu Yasuo
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of anti-miRNA oligonucleotides with stable duplexes to control cardiac diseases.
- Principal Investigator
  
  Komatsu Yasuo
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Drug development chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Analysis of beat fluctuations in cardiomyocytes by scanning electrochemical microscopyPrincipal Investigator
- Principal Investigator
  
  Hirano Yu
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Analysis of cellular functions in primary cells usingscanning electrochemical microscopyPrincipal Investigator
- Principal Investigator
  
  HIRANO Yu
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
Development of functional microelectrode for evaluation of cell membrane functionPrincipal Investigator
- Principal Investigator
  
  HIRANO Yu
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology
ナノプローブ電極を利用した高機能電気化学顕微鏡の開発Principal Investigator
- Principal Investigator
  
  平野悠
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Analytical chemistry
- Research Institution
  National Institute of Advanced Industrial Science and Technology

[Book] 不凍タンパク質の機能と応用2018
- Author(s)
  平野悠　ほか　（監修　津田栄）
- Total Pages
  290
- Publisher
  シーエムシー出版
- ISBN
  9784781313399
- Data Source
  KAKENHI-PROJECT-17K05917
[Journal Article] Promotion of cytoplasmic localization of oligonucleotides by connecting cross-linked duplexes2022
- Author(s)
  Hirano Yu、Komatsu Yasuo
- Journal Title
  
  RSC Advances
  
  Volume: 12 Issue: 38 Pages: 24471-24477
- DOI
  10.1039/d2ra04375k
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05123, KAKENHI-PROJECT-20H03372
[Journal Article] Synthesis of crosslinked 2′-OMe RNA duplexes and their application for effective inhibition of miRNA function2021
- Author(s)
  Abdelhady Ahmed Mostafa、Hirano Yu、Onizuka Kazumitsu、Okamura Hidenori、Komatsu Yasuo、Nagatsugi Fumi
- Journal Title
  
  Bioorg. Med. Chem. Lett.
  
  Volume: 48 Pages: 128257-128257
- DOI
  10.1016/j.bmcl.2021.128257
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03372, KAKENHI-PROJECT-20H02855, KAKENHI-PROJECT-21K05123, KAKENHI-PROJECT-21K19038
[Journal Article] Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation2021
- Author(s)
  Okumura Sho、Hirano Yu、Komatsu Yasuo
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 11467-11467
- DOI
  10.1038/s41598-021-90972-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03372, KAKENHI-PROJECT-21K05123
[Journal Article] Inhibition of breast cancer cell proliferation with anti-microRNA oligonucleotides flanked by interstrand cross-linked duplexes2020
- Author(s)
  Okumura Sho、Hirano Yu、Komatsu Yasuo
- Journal Title
  
  Nucleosides, Nucleotides & Nucleic Acids
  
  Volume: 39 Issue: 1-3 Pages: 225-235
- DOI
  10.1080/15257770.2019.1671595
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K05917, KAKENHI-PROJECT-16H05106
[Journal Article] Facile control of surface crystallographic orientation of anodized nanoporous gold catalyst and its application for highly efficient hydrogen evolution reaction2020
- Author(s)
  Mie Yasuhiro、Takayama Haruka、Hirano Yu
- Journal Title
  
  Journal of Catalysis
  
  Volume: 389 Pages: 476-482
- DOI
  10.1016/j.jcat.2020.06.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07024, KAKENHI-PROJECT-17K05917
[Journal Article] Adsorptive Stripping Voltammetry for the Determination of Dissolved Oxygen Using a Mesoporous Pt Microelectrode2019
- Author(s)
  Masiki Ikegami, Yu Hirano, Yasuhiro Mie, Yasuo Komatsu
- Journal Title
  
  Journal of The Electrochemical Society
  
  Volume: 166 Issue: 6 Pages: B542-B546
- DOI
  10.1149/2.0021908jes
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K05917, KAKENHI-PROJECT-16K08218, KAKENHI-PROJECT-16H05106
[Journal Article] Synthesis and Application of Interstrand Cross-Linked Duplexes by Covalently Linking a Pair of Abasic Sites2018
- Author(s)
  Hirano Yu、Kojima Naoshi、Komatsu Yasuo
- Journal Title
  
  Current Protocols in Nucleic Acid Chemistry
  
  Volume: 75 Issue: 1
- DOI
  10.1002/cpnc.63
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K05917, KAKENHI-PROJECT-16H05106
[Journal Article] Function Control of Anti-microRNA Oligonucleotides Using Interstrand Cross-Linked Duplexes2018
- Author(s)
  Yasuhiro Mie, Yu Hirano, Keiko Kowata, Akiyoshi Nakamura, Mayu Yasunaga, Yoshihiro Nakajima, Yasuo Komatsu
- Journal Title
  
  MOLECULAR THERAPY-NUCLEIC ACIDS
  
  Volume: 10 Pages: 64-74
- DOI
  10.1016/j.omtn.2017.11.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K08218, KAKENHI-PROJECT-17K05917, KAKENHI-PROJECT-16H05106, KAKENHI-PROJECT-16H03295
[Journal Article] Analysis of time-course drug response in rat cardiomyocytes cultured on a pattern of islands2018
- Author(s)
  Okumura Sho、Hirano Yu、Maki Yoshiyuki、Komatsu Yasuo
- Journal Title
  
  The Analyst
  
  Volume: 143 Issue: 17 Pages: 4083-4089
- DOI
  10.1039/c8an01033a
- NAID
  120006718705
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K05917
[Journal Article] Bienzyme reactions on cross-linked DNA scaffolds for electrochemical analysis.2017
- Author(s)
  Hirano, Y., Ikegami, M., Kowata, K. and Komatsu, Y.
- Journal Title
  
  Bioelectrochemistry
  
  Volume: 113 Pages: 15-19
- DOI
  10.1016/j.bioelechem.2016.08.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25410162
[Journal Article] Fabrication and characterization of nanoporous gold on microelectrode2016
- Author(s)
  Masiki Ikegami, Yu Hirano, Yasuhiro Mie, Yasuo Komatsu
- Journal Title
  
  Journal of Electroanalytical Chemistry
  
  Volume: 783 Pages: 188-191
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25410162
[Journal Article] Fabrication and characterization of nanoporous gold on microelectrode.2016
- Author(s)
  Ikegami, M., Hirano, Y., Mie, Y. and Komatsu, Y.
- Journal Title
  
  J. Electroanalytical Chem.
  
  Volume: 783 Pages: 188-191
- DOI
  10.1016/j.jelechem.2016.11.023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25460055
[Journal Article] Analysis of beat fluctuations and oxygen consumption in cardiomyocytes by scanning electrochemical microscopy.2014
- Author(s)
  Hirano, Y., Kodama, M., Shibuya, M., Maki, Y. and Komatsu, Y.
- Journal Title
  
  Anal. Biochem.
  
  Volume: 447C Pages: 39-42
- DOI
  10.1016/j.ab.2013.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25410162, KAKENHI-PROJECT-25620121
[Journal Article] Development of a scanning electrochemical microscopy-based micropipette and its application to analysis of topographic change of single-cell2013
- Author(s)
  平野　悠
- Journal Title
  
  bioelectrochemistry
  
  Volume: 92 Pages: 1-5
- DOI
  10.1016/j.bioelechem.2013.01.004
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23750095, KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25620121
[Journal Article] Direct Electrochemistry of Microsomal Human Flavin-containing Monooxygenases 1 and 3 on Naphthalenethiol Thin Films.2013
- Author(s)
  Ikegami, M., Mie, Y., Hirano, Y. and Komatsu, Y.
- Journal Title
  
  Ecs Electrochemistry Letters
  
  Volume: 2 Issue: 12 Pages: G5-G7
- DOI
  10.1149/2.003312eel
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293030, KAKENHI-PROJECT-25410162, KAKENHI-PROJECT-25620121
[Journal Article] Improvement of Detectable Sensitivity for Enzyme Reaction by Scanning Electrochemical Microscopy with Distance Control System for Immunosensing2012
- Author(s)
  Yu Hirano, Tomoyuki Yasukawa, Yoshiaki Mase, Daisuke Oyamatsu, Hitoshi Shiku, Fumio Mizutani, Tomokazu Matsue
- Journal Title
  
  Electrochemistry
  
  Volume: 80 Issue: 1 Pages: 30-32
- DOI
  10.5796/electrochemistry.80.30
- NAID
  10029981363
- ISSN
  1344-3542, 2186-2451
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22245011, KAKENHI-PROJECT-23750095
[Journal Article] Preparation of Immunosensors using a Microfluidic Device with an Interdigitated Array Electrode Modified with Antibodies.2010
- Author(s)
  Y. Hirano, T. Yasukawa, Y. Sawayashiki, H. Shiku F. Mizutani, T. Matsue
- Journal Title
  
  Electrochemistry 78
  
  Pages: 175-177
- NAID
  130002150585
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750068
[Journal Article] Construction of Time-Lapse Scanning Electrochemical Microscopy with Temperature Control and Its Application To Evaluate the Preservation Effects of Antifreeze Proteins on Living Cells2008
- Author(s)
  Yu Hirano
- Journal Title
  
  Analytical Chemistry 80
  
  Pages: 9349-9354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750068
[Journal Article] Hypothermic preservation effect on mammalian cells of type III antifreeze proteins2008
- Author(s)
  Y. Hirano, Y. Nishimiya, S. Matsumoto, M. Matsushita, S. Todo, A. Miura, Y. Komatsu, S. Tsuda
- Journal Title
  
  57
  
  Pages: 46-51
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750068
[Journal Article] Construction of Time-Lapse Scanning Electrochemical Microscopy with Temperature Control and Its Application to Evaluate the Preservation Effects of Antifreeze Proteins on Living Cells.2008
- Author(s)
  Y. Hirano, Y. Nishimiya, K. Kowata, F. Mizutani, S. Tsuda, Y. Komatsu
- Journal Title
  
  Anal. Chem. 80
  
  Pages: 9349-9354
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20750068
[Journal Article] Topographic, electrochemical, and optical images captured using standing approach mode scanning electrochemical/optical microscopy2006
- Author(s)
  Y.Takahashi, Y.Hirano et al.
- Journal Title
  
  LANGMUIR 25
  
  Pages: 10299-10299
- Data Source
  KAKENHI-PROJECT-18750070
[Patent] マイクロ電極の電極表面の処理方法、表面処理マイクロ電極の製造方法及び表面処理マイクロ電極2015
- Inventor(s)
  池上真志樹、平野悠、小松康雄
- Industrial Property Rights Holder
  池上真志樹、平野悠、小松康雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-093240
- Filing Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-25410162
[Patent] マイクロ電極の電極表面の処理方法、表面処理マイクロ電極の製造方法及び表面処理マイクロ電極2015
- Inventor(s)
  池上真志樹、平野悠、小松康雄
- Industrial Property Rights Holder
  池上真志樹、平野悠、小松康雄
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-093240
- Filing Date
  2015-04-30
- Data Source
  KAKENHI-PROJECT-25293030
[Patent] 核酸複合体、核酸ハイブリダイゼーションの形成方法、医薬組成物、核酸検出用プローブ及び相補鎖核酸複合体2014
- Inventor(s)
  小松康雄、平野　悠、三重安弘
- Industrial Property Rights Holder
  小松康雄、平野　悠、三重安弘
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-251847
- Filing Date
  2014-12-12
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] 安定化した2本鎖構造を有するアンチセンス核酸の細胞内動態2023
- Author(s)
  平野悠、小松康雄
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-20H03372
[Presentation] 安定化した2本鎖構造を有するアンチセンス核酸の細胞内動態2023
- Author(s)
  平野悠，小松康雄
- Organizer
  日本核酸医薬学会第8回年会
- Data Source
  KAKENHI-PROJECT-21K05123
[Presentation] ２本鎖構造を有するアンチセンス核酸の細胞内局在2022
- Author(s)
  平野悠、小松康雄
- Organizer
  核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K05123
[Presentation] ２本鎖構造を利用したアンチセンス核酸の細胞内局在の制御2022
- Author(s)
  平野悠、小松康雄
- Organizer
  日本核酸医薬学会第7回年会
- Data Source
  KAKENHI-PROJECT-20H03372
[Presentation] ２本鎖構造を利用したアンチセンス核酸の細胞内局在の制御2022
- Author(s)
  平野悠、小松康雄
- Organizer
  核酸医薬学会
- Data Source
  KAKENHI-PROJECT-21K05123
[Presentation] ２本鎖構造を有するアンチセンス核酸の細胞内局在2021
- Author(s)
  平野悠、小松康雄
- Organizer
  日本核酸医薬学会第6回年会
- Data Source
  KAKENHI-PROJECT-20H03372
[Presentation] Effect of terminal double-stranded structures on intracellular localization of anti-miRNA oligonucleotide2019
- Author(s)
  平野悠、千高佐知子、小松康雄
- Organizer
  International Symposium on Nucleic Acids Chemistry 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05917
[Presentation] クロスリンク２本鎖構造によるanti-miRNAオリゴの細胞内局在への影響2019
- Author(s)
  平野悠、扇谷仁希、千高佐知子、三重安弘、小松康雄
- Organizer
  核酸医薬学会　第5回年会
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] クロスリンク２本鎖構造によるanti-miRNAオリゴの細胞内局在への影響2019
- Author(s)
  平野悠、扇谷　仁希、千高佐知子、三重安弘、小松康雄
- Organizer
  核酸医薬学会　第4回年会
- Data Source
  KAKENHI-PROJECT-17K05917
[Presentation] International Symposium on Nucleic Acids Chemistry 20192019
- Author(s)
  平野悠、千高佐知子、小松康雄
- Organizer
  日本核酸化学会
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] 微細構造白金マイクロ電極を用いた溶存酸素の検出2018
- Author(s)
  池上真志樹, 平野悠, 三重安弘
- Organizer
  応用物理学会
- Data Source
  KAKENHI-PROJECT-17K05917
[Presentation] クロスリンク２本鎖構造を有するanti-miRNAオリゴ核酸の細胞内動態2018
- Author(s)
  平野悠, 扇谷仁希, 三重安弘, 小綿恵子, 小松康雄
- Organizer
  核酸医薬学会　第4回年会
- Data Source
  KAKENHI-PROJECT-17K05917
[Presentation] 走査型電気化学顕微鏡用の白金/金コンポジット微細構造電極の開発2018
- Author(s)
  池上真志樹、平野　悠、三重安弘、小松康雄
- Organizer
  第65回応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] クロスリンク２本鎖構造を有するanti-miRNAオリゴ核酸の細胞内動態2018
- Author(s)
  平野悠、扇谷仁希、三重安弘、小綿恵子、小松康雄
- Organizer
  核酸医薬学会　第4回年会
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] 架橋化構造を有するanti-miRNAオリゴによる神経膠芽腫細胞の増殖抑制効果2017
- Author(s)
  三重安弘、平野悠、小綿恵子、小松康雄
- Organizer
  日本核酸医薬学会第3回年会
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] アノード溶解によるナノポーラスゴールド形成の電極サイズ依存性2017
- Author(s)
  池上真志樹、平野　悠、三重安弘、小松康雄
- Organizer
  応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] アノード溶解によるナノポーラスゴールド形成の電極サイズ依存性2017
- Author(s)
  池上真志樹、平野悠、三重安弘、小松康雄
- Organizer
  第64回応用物理学会春季学術講演会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2017-03-14
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] Construction of a bienzyme immobilizing microelectrode by cross-linked DNA scaffolds and its application to analysis of cellular metabolism.2017
- Author(s)
  平野悠、池上真志樹、小綿恵子、小松康雄
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry 2017
- Data Source
  KAKENHI-PROJECT-16H05106
[Presentation] 走査型電気化学顕微鏡用の白金/金コンポジット微細構造電極の開発2017
- Author(s)
  池上真志樹, 平野悠, 三重安弘, 小松康雄
- Organizer
  第65回応用物理学会春季学術講演会
- Data Source
  KAKENHI-PROJECT-17K05917
[Presentation] Construction of a bienzyme immobilizing microelectrode by cross-linked DNA scaffolds and its application to analysis of cellular metabolism2017
- Author(s)
  平野悠, 池上真志樹, 小綿恵子, 小松康雄
- Organizer
  The 44th International Symposium on Nucleic Acids Chemistry 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K05917
[Presentation] クロスリンク２本鎖構造を有する anti-miRNA オリゴ核酸の構造と miRNA 阻害活性との相関2016
- Author(s)
  三重安弘、平野　悠、小綿恵子、中村彰良、安永茉由、中島芳浩、小松康雄
- Organizer
  日本核酸医薬学会第2回年会
- Place of Presentation
  東京理科大学葛飾キャンパス（東京都葛飾区）
- Year and Date
  2016-11-15
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] 走査型電気化学顕微鏡を基盤とした心筋細胞解析システムの開発2016
- Author(s)
  奥村翔、平野悠、小松康雄、牧与志幸
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-12-01
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] 走査型電気化学顕微鏡を用いた心筋細胞の拍動解析2016
- Author(s)
  奥村翔、平野悠、小松康雄、牧与志幸
- Organizer
  第25回日本バイオイメージング学会
- Place of Presentation
  名古屋市立大学薬学部宮田専治記念ホール（名古屋市瑞穂区）
- Year and Date
  2016-09-04
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] 走査型電気化学顕微鏡を用いた心筋細胞の拍動解析2016
- Author(s)
  奥村翔、平野悠、小松康雄、牧与志幸
- Organizer
  日本バイオイメージング学会
- Place of Presentation
  名古屋市立大学薬学部、名古屋市
- Year and Date
  2016-09-06
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] 走査型電気化学顕微鏡を基盤とした心筋細胞解析システムの開発2016
- Author(s)
  奥村翔、平野悠、小松康雄、牧与志幸
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] Structure-function relationship of anti-miRNA oligonucleotides modified with interstrand cross-links.2016
- Author(s)
  三重安弘、小綿恵子、平野悠、中村彰良、安永茉由、中島芳浩、小松康雄
- Organizer
  The 21st Annual Meeting of the RNA Society
- Place of Presentation
  国立京都国際会館（京都市左京区）
- Year and Date
  2016-06-28
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] クロスリンク2本鎖を有する核酸のmiRNA阻害効果と構造の相関性2016
- Author(s)
  小綿恵子、三重安弘、平野悠、中村彰良、安永茉由、中島芳浩、小松康雄
- Organizer
  日本薬学会第136年会
- Place of Presentation
  パシフィコ横浜、横浜市
- Year and Date
  2016-03-28
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] Interstrand cross-link of 2′-O-Methyl RNA duplexes and its application as miRNA inhibitors.2015
- Author(s)
  三重安弘、平野悠、小綿恵子、中村彰良、安永茉由、中島芳浩、小松康雄
- Organizer
  日本核酸医薬学会第1回年会
- Place of Presentation
  京都テルサ、京都市
- Year and Date
  2015-11-30
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] 2′-O-Methyl RNA 2本鎖の分子内架橋化反応とmiRNA阻害核酸への展開2015
- Author(s)
  三重安弘、平野悠、小綿恵子、小松康雄
- Organizer
  第17 回日本RNA 学会年会
- Place of Presentation
  ホテルライフォート札幌、札幌市
- Year and Date
  2015-07-15
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] Development of scanning electrochemical microscopy for living cells2014
- Author(s)
  平野　悠
- Organizer
  2nd BPPT-AIST Joint Symposium
- Place of Presentation
  北海道
- Year and Date
  2014-09-10
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] 走査型電気化学顕微鏡を利用した心筋細胞の拍動解析技術の開発2013
- Author(s)
  平野悠、小玉実生恵、渋谷真宏、牧与志幸、小松康雄
- Organizer
  日本分析化学会第62年会
- Place of Presentation
  近畿大学　東大阪キャンパス（大阪府）
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] Electrochemical monitoring of enzyme reactions promoted on double stranded DNA2011
- Author(s)
  平野　悠
- Organizer
  第38回国際核酸化学シンポジウム
- Place of Presentation
  札幌北海道大学
- Data Source
  KAKENHI-PROJECT-23750095
[Presentation] Electrochemical monitoring of enzyme reactions promoted on double stranded DNA2011
- Author(s)
  Y. Hirano, K. Ichikawa, N. Kojima, and Y. Komatsu
- Organizer
  第38回国際核酸化学シンポジウム
- Place of Presentation
  北海道大学(北海道)
- Year and Date
  2011-11-10
- Data Source
  KAKENHI-PROJECT-23750095
[Presentation] キャピラリー添加と走査型電気化学顕微鏡を併用した一細胞連続観察システムの開発2009
- Author(s)
  平野悠
- Organizer
  日本分析化学会
- Place of Presentation
  北海道大学(札幌)
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-20750068
[Presentation] キャピラリー添加と走査型電気化学顕微鏡を併用した一細胞連続観察システムの開発2009
- Author(s)
  平野悠
- Organizer
  日本分析化学会
- Place of Presentation
  札幌
- Year and Date
  2009-09-24
- Data Source
  KAKENHI-PROJECT-20750068
[Presentation] 低温環境下の細胞を評価するための走査型電気化学顕微鏡の開発2008
- Author(s)
  平野悠
- Organizer
  日本分析化学会
- Place of Presentation
  福岡
- Year and Date
  2008-09-10
- Data Source
  KAKENHI-PROJECT-20750068
[Presentation] 樹脂製ニードル型マイクロ電極の開発とその特性
- Author(s)
  平野悠、小松康雄
- Organizer
  電気化学会
- Place of Presentation
  関西大学千里山キャンパス（大阪府）
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] 電気化学測定を利用した一細胞動態解析技術の開発と細胞毒性試験への展開
- Author(s)
  平野悠、小綿恵子、小玉実生恵、小松康雄
- Organizer
  シンポジウム：細胞アッセイ技術の現状と将来
- Place of Presentation
  東京大学生産技術研究所コンベンションホール（東京都）
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] 2本鎖間架橋化DNAを活用した電極界面上での酵素反応場の構築
- Author(s)
  平野悠、小玉実生恵、小綿恵子、池上真志樹、小松康雄
- Organizer
  薬学会第134年会
- Place of Presentation
  熊本大学（熊本県）
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] フラビン含有モノオキシゲナーゼを用いた酵素固定化電極
- Author(s)
  池上真志樹、三重安弘、平野悠、小松康雄
- Organizer
  応用物理学会春季学術講演会
- Place of Presentation
  青山学院大学相模原キャンパス（神奈川県）
- Data Source
  KAKENHI-PROJECT-25410162
[Presentation] 査型電気化学顕微鏡を利用した心筋細胞の拍動解析技術の開発
- Author(s)
  平野悠, 小玉実生恵, 牧　与志幸, 渋谷真広, 小松康雄
- Organizer
  日本分析化学会第62年会
- Place of Presentation
  近畿大学
- Data Source
  KAKENHI-PROJECT-25293030
[Presentation] 2本鎖間架橋化DNAを活用した電極界面上での酵素反応場の構築
- Author(s)
  平野悠, 小玉実生恵, 小綿恵子, 池上真志樹, 小松康雄
- Organizer
  薬学会第134年会
- Place of Presentation
  熊本大学
- Data Source
  KAKENHI-PROJECT-25293030

1. Komatsu Yasuo (30271670)

# of Collaborated Projects: 3 results

# of Collaborated Products: 26 results
2. 周東智 (70241346)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. 南川典昭 (40209820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 三重安弘

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Hirano Yu 平野 悠

HIRANO Yu 平野 悠

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miRNA制御核酸の機能を細胞単位で解析する技術の開発Principal Investigator

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Complex formation between RNA cleaving-enzyme and antisense and its application to regulation of long non-coding RNAs.

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Development of microbiosensor with DNA scaffolds for cell metabolic analysisPrincipal Investigator

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Development of anti-miRNA oligonucleotides on the basis of structure control.

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Development of anti-miRNA oligonucleotides with stable duplexes to control cardiac diseases.

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Analysis of beat fluctuations in cardiomyocytes by scanning electrochemical microscopyPrincipal Investigator

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Analysis of cellular functions in primary cells usingscanning electrochemical microscopyPrincipal Investigator

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Development of functional microelectrode for evaluation of cell membrane functionPrincipal Investigator

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ナノプローブ電極を利用した高機能電気化学顕微鏡の開発Principal Investigator

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[Book] 不凍タンパク質の機能と応用2018

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[Journal Article] Promotion of cytoplasmic localization of oligonucleotides by connecting cross-linked duplexes2022

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[Journal Article] Synthesis of crosslinked 2′-OMe RNA duplexes and their application for effective inhibition of miRNA function2021

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[Journal Article] Stable duplex-linked antisense targeting miR-148a inhibits breast cancer cell proliferation2021

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Hirano Yu 平野悠

HIRANO Yu 平野悠