Kanai Masashi 金井雅史

… Alternative Names

KANAI MASASHI 金井雅史

KANAI Masashi 金井雅史

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Researcher Number	70432416
Other IDs
Affiliation (Current)	2025: 関西医科大学, 医学部, 教授 2025: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2025: 関西医科大学, 医学部, 教授 2019: 京都大学, 医学研究科, 准教授 2016 – 2018: 京都大学, 医学研究科, 特定准教授 2015: 京都大学, 医学(系)研究科(研究院), 准教授 2012 – 2014: 京都大学, 医学(系)研究科(研究院), 講師 … More 2010: Kyoto University, 医学研究科, 特定助教 2007 – 2009: Kyoto University, 医学研究科, 助教 2008: Kyoto University, 大学院・医学研究科, 助教 Less
Review Section/Research Field	Principal Investigator Gastroenterology / Basic Section 50020:Tumor diagnostics and therapeutics-related / Medical pharmacy / Applied pharmacology Except Principal Investigator General pharmacology / Medical sociology
Keywords	Principal Investigator オキサリプラチン / 膵癌 / pharmacogenetics / 個別化治療 / 神経障害 / 次世代シーケンス / 白金製剤 / 相同組み換え修復異常 / DNA修復異常 / がん遺伝子パネル検査 … More / ゲノム / 個別化医療 / 相同修復組み換え遺伝子 / BRCA / ゲノム医療 / 膵がん / 抗がん薬 / miRNA / QOL / マイクロRNA / がん / クルクミン / pharmacogenomics / 薬理遺伝学 / がん化学療法 / 化学療法 / 大腸癌 … More Except Principal Investigator 心筋保護 / 薬物療法 / がん / 心筋障害 / エネルギー代謝 / オートファジー / ミトコンドリア / 抗がん剤 / 心不全 / TAPS / CTCAE / RECIST / ガイドライン / 臨床腫瘍学 / がん診療 / 医学教育学 Less

オキサリプラチンの至適投与法に関する研究Principal Investigator
- Principal Investigator
  
  金井雅史
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kansai Medical University
Development of precision medicine for patients with pancreatic cancer who harbor homologous recombinant repair genesPrincipal Investigator
- Principal Investigator
  
  KANAI MASASHI
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical pharmacy
- Research Institution
  Kyoto University
Research for heart protection during cancer chemotherapy via regulating cardiac autophagy
- Principal Investigator
  
  Iwai-Kanai Eri
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  Tenri Health Care University
Investigation of a novel anti-cancer effects of curcumin using comprehensive miRNA expression analysisPrincipal Investigator
- Principal Investigator
  
  KANAI MASASHI
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied pharmacology
- Research Institution
  Kyoto University
Pharmacogenetic study to predicting clinical response of oxaliplatin in patients with advanced colorectal cancerPrincipal Investigator
- Principal Investigator
  
  KANAI Masashi
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Educational system of oncology
- Principal Investigator
  
  YANAGIHARA Kazuhiro
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Medical sociology
- Research Institution
  Kyoto University
Pharmacogenetic analysis of clinical response to oxaliplatin-based Chemotherapy in colorectal cancer patientsPrincipal Investigator
- Principal Investigator
  
  KANAI Masashi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University

All 2019 2018 2017 2016 2015 2014 2013 2012 2011 2010 2009 2008 2007 Other

All Journal Article Presentation Book

[Book] 肝と膵2019
- Author(s)
  金井　雅史
- Total Pages
  4
- Publisher
  医学図書出版
- Data Source
  KAKENHI-PROJECT-17K08413
[Book] 分子消化器病(遺伝子多型解析は消化器癌化学療法にどのように役に立つのか?)2011
- Author(s)
  金井雅史、松本繁巳、千葉勉
- Publisher
  (in press)
- Data Source
  KAKENHI-PROJECT-21790661
[Book] 分子消化器病「消化器癌治療薬選択のための遺伝子検査」2010
- Author(s)
  金井雅史、千葉勉
- Total Pages
  5
- Publisher
  先端医学社
- Data Source
  KAKENHI-PROJECT-21790661
[Book] 外科治療(胆道癌補助化学療法の実際)第102号2010
- Author(s)
  田浦康二郎、波多野悦朗、金井雅史、上本伸二
- Data Source
  KAKENHI-PROJECT-21790661
[Book] 分子消化器病(消化器癌治療薬選択のための遺伝子検査)7巻4号2010
- Author(s)
  金井雅史、千葉勉
- Data Source
  KAKENHI-PROJECT-21790661
[Book] 伏見医報(分子標的薬剤を用いた消化器がん化学療法の現状)6072010
- Author(s)
  金井雅史
- Total Pages
  277
- Data Source
  KAKENHI-PROJECT-21790661
[Book] 最近の消化器癌化学療法の進歩-大腸癌化学療法を中心に, 西宮医師会雑誌第14号2009
- Author(s)
  金井雅史
- Data Source
  KAKENHI-PROJECT-19790482
[Book] 臨床消化器内科2008
- Author(s)
  八隅秀二郎、金井雅史、高忠之、浅田全範、上野憲司、多田真輔
- Total Pages
  7
- Publisher
  日本メディカルセンター
- Data Source
  KAKENHI-PROJECT-19790482
[Book] 膵癌化学療法の治療効果判定, 臨床消化器内科23巻8号2008
- Author(s)
  八隅秀二郎, 金井雅史, 高忠之, 浅田全範, 上野憲司, 多田真輔
- Data Source
  KAKENHI-PROJECT-19790482
[Book] がん患者を受け持ったら, 臨床研修プラクティス4巻6号2007
- Author(s)
  金井雅史
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer2018
- Author(s)
  Kondo Tomohiro、Kanai Masashi、Kou Tadayuki、Sakuma Tomohiro、Mochizuki Hiroaki、Kamada Mayumi、Nakatsui Masahiko、Uza Norimitsu、Kodama Yuzo、Masui Toshihiko、Takaori Kyoichi、Matsumoto Shigemi、Miyake Hidehiko、Okuno Yasushi、Muto Manabu
- Journal Title
  
  Oncotarget
  
  Volume: 9 Issue: 28 Pages: 19817-19825
- DOI
  10.18632/oncotarget.24865
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08413, KAKENHI-PROJECT-18H02692
[Journal Article] Activation of PPARα in the early stage of heart failure maintained myocardial function and energetics in pressure overload heart failure.2017
- Author(s)
  Kaimoto S, Hoshino A, Ariyoshi M, Okawa Y, Tateishi S, Ono K, Uchihashi M, Fukai K, Iwai-Kanai E, Matoba S.
- Journal Title
  
  Am J Physiol Heart Circ Physiol. 2017
  
  Volume: ３１２（２）
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460350
[Journal Article] Cardiac Cellular Fate in the Adrenergic Overload.2016
- Author(s)
  Iwai-Kanai E .
- Journal Title
  
  Bul Tenri Heal Car
  
  Volume: ４（１） Pages: 33-33
- NAID
  40020922692
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460350
[Journal Article] D-Glutamate is metabolized in the heart mitochondria.2016
- Author(s)
  M. Ariyoshi, M. Katane, K. Hamase, Y. Miyoshi, M. Nakane, A. Hoshino, Y. Okawa, Y. Mita, S. Kaimoto, M. Uchihashi, K. Fukai, K. Ono, S. Tateishi, D. Hato, R. Yamanaka, S. Honda, Y. Fushimura, E. Iwai-Kanai, N. Ishihara, M. Mita, H. Homma, and S. Matoba.
- Journal Title
  
  Sci. Rep.
  
  Volume: 7 Issue: 1 Pages: 43911-43911
- DOI
  10.1038/srep43911
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01209, KAKENHI-PROJECT-26291044, KAKENHI-PROJECT-26460350, KAKENHI-PROJECT-15K09144, KAKENHI-PROJECT-16K18707, KAKENHI-PROJECT-17K08609, KAKENHI-PROJECT-17H03677
[Journal Article] alpha-adrenergic agonist protects hearts by inducing Akt1-mediated autophagy.2015
- Author(s)
  Nakaoka M, Iwai-Kanai E, Katamura M, Okawa Y, Mita Y, Matoba S.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 456(1) Pages: 250-6
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460350
[Journal Article] An alpha-adrenergic agonist protects hearts by inducing Akt1-mediated autophagy.2015
- Author(s)
  Nakaoka M, Iwai-Kanai E, Katamura M, Okawa Y, Mita Y, Matoba S.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 456 Issue: 1 Pages: 250-6
- DOI
  10.1016/j.bbrc.2014.11.067
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790773, KAKENHI-PROJECT-26460350
[Journal Article] Comparative Outcomes between Initially Unresectable and Recurrent Cases of Advanced Pancreatic Cancer Following Palliative Chemotherapy2014
- Author(s)
  Xue P, Kanai M, Mori Y, Nishimura T, Uza N, Kodama Y, Kawaguchi Y, Takaori K, Matsumoto S, Uemoto S, Chiba T.
- Journal Title
  
  Pancreas
  
  Volume: 43 Issue: 3 Pages: 411-416
- DOI
  10.1097/mpa.0000000000000050
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] Neutrophil-to-Lymphocyte Ratio for Predicting Palliative Chemotherapy Outcomes in Advanced Pancreatic Cancer Patients2014
- Author(s)
  Xue P, Kanai M, Mori Y, Nishimura T, Uza N, Kodama Y, Kawaguchi Y, Takaori K, Matsumoto S, Uemoto S, Chiba T
- Journal Title
  
  Cancer Medicine
  
  Volume: 3 Pages: 406-415
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] Patients with recurrent biliary tract cancer have a better prognosis than those with unresectable disease: retrospective analysis of a multi-institutional experience with patients of advanced biliary tract cancer who received palliative chemotherapy2014
- Author(s)
  Ikezawa K, Kanai M, Ajiki T, Tsukamoto T, Toyokawa H, Terajima H, Furuyama H, Nagano H, Ikai I, Kuroda N, Awane M, Ochiai T, Takemura S, Miyamoto A, Kume M, Ogawa M, Takeda Y, Taira K, Ioka T
- Journal Title
  
  J Hepatobiliary Pancreat Sci
  
  Volume: 21 Issue: 2 Pages: 98-104
- DOI
  10.1002/jhbp.2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] Oxidative post-translational modifications develop LONP1 dysfunction in pressure overload heart failure.2014
- Author(s)
  Hoshino A, Okawa Y, Ariyoshi M, Kaimoto S, Uchihashi M, Fukai K, Iwai-Kanai E, Matoba S.
- Journal Title
  
  Circ Heart Fail.
  
  Volume: 7(3) Issue: 3 Pages: 500-509
- DOI
  10.1161/circheartfailure.113.001062
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26460350
[Journal Article] Therapeutic application of curcumin for patients with pancreatic cancer2014
- Author(s)
  Kanai M
- Journal Title
  
  World Journal of Gastroenterology
  
  Volume: 20 Pages: 9384-9391
- NAID
  120005522517
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] Curcumin attenuates doxorubicin-induced cardiotoxicity by inducing autophagy via the　regulation of JNK phosphorylation2014
- Author(s)
  M Katamura, E Iwai-Kanai, M Nakaoka, Y Okawa, M Ariyoshi, Y Mita, A Nakamura, K Ikeda, T Ogata, T Ueyama, S Matoba
- Journal Title
  
  J Clin Exp Cardiolog
  
  Volume: 5 Issue: 09 Pages: 337-337
- DOI
  10.4172/2155-9880.1000337
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24790773, KAKENHI-PROJECT-26460350
[Journal Article] Comparative Outcomes of Elderly and Non-elderly Patients Receiving First-Line Palliative Chemotherapy for Advanced Biliary Tract Cancer.2014
- Author(s)
  Kou T, Kanai M, Ikezawa K, Ajiki T, Tsukamoto T, Toyokawa H, Yazumi S, Terajima H, Furuyama H, Nagano H, Ikai I, Kuroda N, Awane M, Ochiai T, Takemura S, Miyamoto A, Kume M, Ogawa M, Takeda Y, Taira T, Ioka T
- Journal Title
  
  J Gastroenterol Hepatol
  
  Volume: 29 Issue: 2 Pages: 403-408
- DOI
  10.1111/jgh.12338
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] A phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin(®)) in cancer patients2013
- Author(s)
  Kanai M, Otsuka Y, Otsuka K, Sato M, Nishimura T, Mori Y, Kawaguchi M, Hatano E, Kodama Y, Matsumoto S, Murakami Y, Imaizumi A, Chiba T, Nishihira J, Shibata H.
- Journal Title
  
  Cancer Chemother Pharmacol
  
  Volume: Epub ahead of print
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] A Phase I study investigating the safety and pharmacokinetics of highly bioavailable curcumin (Theracurmin) in cancer patients2013
- Author(s)
  Kanai M
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
  
  Volume: on line Issue: 6 Pages: 1-10
- DOI
  10.1007/s00280-013-2151-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22501041, KAKENHI-PROJECT-24590655
[Journal Article] A single-center analysis of the survival benefits of adjuvant gemcitabine chemotherapy for biliary tract cancer2013
- Author(s)
  Yamanaka K, Hatano E, Kanai M, Tanaka S, Yamamoto K, Narita M, Nagata H, Ishii T, Machimoto T, Taura K, Uemoto S.
- Journal Title
  
  Int J Clin Oncol
  
  Volume: 未確定
- NAID
  120005652822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24590655
[Journal Article] Dose-escalation and pharmacokinetic study of nanoparticlecurcumin, apotential anticancer agent with improved bioavailability, in health human volunteers.2011
- Author(s)
  Kanai M, Imaizumi A, Otsuka Y, Sasaki H, Hashiguchi M, Tsujiko K, Matsumoto S,Ishiguro H, Chiba T.
- Journal Title
  
  Cancer Chemother Pharmacol. (Epub ahead of print)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] A Case of Progressive Digital Ischemia after Early Withdrawal of Gemcitabine and S-1 in a Patient with Systemic Sclerosis.2011
- Author(s)
  Zaima C, Kanai M, Ishikawa S, Kawaguchi Y, Masui T, Mori Y, Nishimura T,Matsumoto S, Yanagihara K, Chiba T, Mimori T.
- Journal Title
  
  Jpn J Clin Oncol. 41(6)
  
  Pages: 803-806
- NAID
  120004225524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Premedication with 20 mg dexamethasone effectively prevents relapse of extensive skin rash associated with gemcitabine monotherapy2010
- Author(s)
  Kanai M, Matsumoto S, Nishimura T, Matsumura Y, Hatano E, Mori A, Masui T, Kawaguchi Y, Nakamura E, Tada S, Kitano T, Ishiguro H, Yanagihara K, Chiba T
- Journal Title
  
  Ann Oncol. 21(1)
  
  Pages: 189-190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Associations between glutathione S-transferase pi Ile^<105>Val and glyoxylate aminotransferase Pro^<11>Leu and Ile^<340>Met polymor phisms and early-onset oxaliplatin-induced neuropathy2010
- Author(s)
  Kanai M, Yoshioka A, Tanaka S, et al
- Journal Title
  
  Cancer Epidemiology 34(in press)
  
  Pages: 189-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] KLF4α Up-regulation Promotes Cell Cycle Progression and Reduces Survival Time of Patients With Pancreatic Cancer.2010
- Author(s)
  Wei D, Wang L, Kanai M (Equal contribution with W.D, W.L), et al.
- Journal Title
  
  Gastroenterology
  
  Volume: 139 Pages: 2135-45
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Premedication with 20 mg dexamethasone effectively prevents relapse of extensive skin rash associated with gemcitabine monotherapy2010
- Author(s)
  Kanai M, Matsumoto S, Nishimura T, et al.
- Journal Title
  
  Ann Oncol
  
  Volume: 21 Pages: 189-90
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Oxaliplatin-free interval as a risk factor for hypersensitivity reaction among colorectal cancer patients treated with FOLFOX2010
- Author(s)
  Mori Y, Nishimura T, Kitano T, Yoshimura K, Matsumoto S, Kanai M, Hazama M, Ishiguro H, Nagayama S, Yanagihara K, Teramukai S, Chiba T, Sakai Y, Fukushima M
- Journal Title
  
  Oncology. 79(1-2)
  
  Pages: 136-143
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] A multi-institution phase II study of gemcitabine/S-1 combination chemotherapy for patients with advanced biliary tract cancer2010
- Author(s)
  Kanai M, Yoshimura K, Tsumura T, Asada M, Suzuki C, Niimi M, Matsumoto S, Nishimura T, Nitta T, Yasuchika K, Taura K, Mori Y, Hamada A, Inoue N, Tada S, Yanagihara K, Yazumi S, Osaki Y, Chiba T, Ikai I, Fukushima M, Uemoto S, Hatano E
- Journal Title
  
  Cancer Chemother Pharmacol 67(6)
  
  Pages: 1429-1434
- NAID
  120003238952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Associations between glutathione S-transferase pi Ile105Val and glyoxylate aminotransferase Pro11Leu and Ile340Met polymorphisms and early-onset oxaliplatin-induced neuropathy2010
- Author(s)
  Kanai M, Yoshioka A, Tanaka S et al.Kanai M, Yoshioka A, Tanaka S, Nagayama S, Matsumoto S, Nishimura T, Niimi M,Teramukai S, Takahashi R, Mori Y, Kitano T, Ishiguro H, Yanagihara K, Chiba T, Fukushima M, Matsuda F
- Journal Title
  
  Cancer Epidemiology 34(2)
  
  Pages: 189-193
- NAID
  120002098847
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer2010
- Author(s)
  Kanai M, Yoshimura K, Asada M, et al
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
- NAID
  120003238951
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] KLF4α Up-regulation Promotes Cell Cycle Progression and Reduces Survival Time of Patients With Pancreatic Cancer.2010
- Author(s)
  Wei D, Wang L, Kanai M, Jia Z, Le X, Li Q, Wang H, Xie K
- Journal Title
  
  Gastroenterology. 139(6)
  
  Pages: 2135-2145
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Phase II study of S-1 and docetaxel for previously treated patients with locally advanced or metastatic non-small cell lung cancer.2010
- Author(s)
  Yanagihara K, Yoshimura K, Niimi M, Yasuda H, Sasaki T, Nishimura T, Ishiguro H, Matsumoto S, Kitano T, Kanai M, Misawa A, Tada H, Teramukai S, Mio T, Fukushima M.
- Journal Title
  
  Cancer Chemother Pharmacol. 66(5)
  
  Pages: 913-918
- NAID
  120002515188
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Associations between glutathione S-transferase pi Ile^<105> Val and glyoxylate aminotransferase Pro^<11> Leu and Ile^<340> Met polymorphisms and early-onset oxaliplatin-induced neuropathy2010
- Author(s)
  Kanai M, Yoshioka A, Tanaka S, et al.
- Journal Title
  
  Cancer Epidemiology
  
  Volume: 34 Pages: 189-193
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Aphase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer.2010
- Author(s)
  Kanai M, Yoshimura K, Asada M, Imaizumi A, Suzuki C, Matsumoto S, Nishimura T, Mori Y, Masui T, Kawaguchi Y, Yanagihara K, Yazumi S, Chiba T, Guha S, Aggarwal BB
- Journal Title
  
  Cancer Chemother Pharmacol. 66(5)
  
  Pages: 913-918
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] A multi-institution phase II study of gemcitabine/S-1 combination chemotherapy for patients with advanced biliary tract cancer2010
- Author(s)
  Kanai M, Yoshimura K, Tsumura T, et al
- Journal Title
  
  Cancer Chemotherapy and Pharmacology
- NAID
  120003238952
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] UGT1A1*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients2009
- Author(s)
  Onoue M, Terada T, Kanai M, et al.
- Journal Title
  
  Int J Clin Oncol. 14
  
  Pages: 136-4
- NAID
  10025147852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] UGT1A1^*6 polymorphism is most predictive of severe neutropenia induced by irinotecan in Japanese cancer patients2009
- Author(s)
  Onoue M, Terada T, Kanai M, et al.(12名中8番)
- Journal Title
  
  Int J Clin Oncol 14
  
  Pages: 136-142
- NAID
  10025147852
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790661
[Journal Article] Safety and efficacy of modified FOLFOX6 for treatment of metastatic or locally advanced colorectal cancer. A single-institution outcome study2008
- Author(s)
  Matsumoto S, Nishimura T, Kanai M, et al.
- Journal Title
  
  Chemotherapy 54(5)
  
  Pages: 395-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Satety and efficacy of modified FOLFOX6 for treatment of metastaticor locally advanced colorectal cancer. A single-institution outcome2008
- Author(s)
  Matsumoto S,Nishimura T, Kanai M, et.al.(15名)
- Journal Title
  
  Chemotherapy 54
  
  Pages: 395-403
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Kruppel-like factor 4 induces p27Kipl expression in and suppresses the growth and metastasis of human pancreatic cancer cells2008
- Author(s)
  Wei D, Kanai M, Jia Z, et.al.(5名)
- Journal Title
  
  Cancer Res 68
  
  Pages: 4631-39
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Clinical outcome of combination therapy of gemcitabine with S-1 for advanced pancreatic cancer2008
- Author(s)
  Yamauchi J, Kanai M, Matsumoto S, et.al.(16名)
- Journal Title
  
  Pancreas 36
  
  Pages: 327-328
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Kruppel-like factor 4 induces p27Kip1 expression in and suppresses the growth and metastasis of human pancreatic cancer cells2008
- Author(s)
  Wei D, Kanai M, Jia Z, et al.
- Journal Title
  
  Cancer Res. Jun 15 68(12)
  
  Pages: 4631-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Clinical outcome of combination therapy of gemcitabine with S-1 for advanced pancreatic cancer2008
- Author(s)
  Yamauchi J, Kanai M, Matsumoto S, et al.
- Journal Title
  
  Pancreas Apr 36(3)
  
  Pages: 327-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Prevalence and incidence of anemia in Japanese cancer patients receiving outpatient chemotherapy2007
- Author(s)
  Kitano T, Tada H, Kanai M, et al.(13名 5番)
- Journal Title
  
  Int J Hematol 86
  
  Pages: 37-41
- NAID
  10018515509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] Prevalence and incidence of anemia in Japanese cancer patients receiving outpatient chemotherapy2007
- Author(s)
  Kitano T, Tada H, Kanai M, et al.
- Journal Title
  
  Int J Hematol. Jul 86(1)
  
  Pages: 37-41
- NAID
  10018515509
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] The efficacy and safety of docetaxel/nedaplatin combination therapy as a second line regimen in advanced esophageal cancer2007
- Author(s)
  Kanai M, Matsumoto S, Nishimura T, et al.(15名 1番)
- Journal Title
  
  Int J Clin Oncol 12
  
  Pages: 224-227
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] The efficacy and safety of docetaxel/nedaplatin combination therapy as a second line regimen in advanced esophageal cancer2007
- Author(s)
  Kanai M, Matsumoto S, Nishimura T, et al.
- Journal Title
  
  Int J Clin Oncol Jun 12(3)
  
  Pages: 224-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Journal Article] A history of smoking is inversely correlated with the incidence of gemcitabine-induced neutropenia
- Author(s)
  Kanai M, Morita S, Nishimura T, et al.
- Journal Title
  
  Ann Oncol (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790482
[Presentation] Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer2019
- Author(s)
  Masashi Kanai
- Organizer
  50th Annual Scientific Meeting of American Pancreatic Association
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08413
[Presentation] がん関連遺伝子パネル (OncoPrimeTM) を用いたprecision medicine2017
- Author(s)
  金井雅史、髙忠之、松本繁巳、武藤学
- Organizer
  第3回日本産科婦人科遺伝診療学会
- Invited
- Data Source
  KAKENHI-PROJECT-17K08413
[Presentation] BDH1は心筋酸化ストレスを軽減し心不全悪化を軽減する2016
- Author(s)
  立石周平　有吉真　内橋基樹　波東大地　山中亮平　金井恵理　的場聖明
- Organizer
  第２５回日本Cell Death 学会
- Place of Presentation
  東京
- Year and Date
  2016-09-09
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] Efficacy and Safety of Therapeutic Angiogenesis by Basic Fibroblast Growth Factor With Atelocollagen Solution in Patients with Critical Limb Ischemia.2016
- Author(s)
  Ohno K, Kojima S, Ariyoshi M, Kaimoto S, Uchihashi M, Kaneda H, Kagimura T, Fukushima M, Iwai-Kanai E, Matoba S.
- Organizer
  AHA Scientific Sessions 2017
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] Age Related Cardiac Dysfunction and Pancreatic β-cell Function in Diabetes Were Improved by P53 Inhibition Through Parkin-mediated Mitophagy.2016
- Author(s)
  Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, Okawa Y, Mita Y, Kaimoto S, Uchihashi M, Fukai K, Ono K, Tateishi S, Hato D, Yamanaka R, Honda S, Fushimura Y, Iwai-Kanai E, Ishihara N, Mita M, Homma H, Matoba S.
- Organizer
  AHA Scientific Sessions 2017
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2016-11-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] Ketone Body Metabolizing Enzyme 3-hydroxybutyrate Dehydrogenase 1 (Bdh1)2015
- Author(s)
  Shuhei Tateishi, Motoki Uchihashi, Atsushi Hoshino, Makoto Ariyoshi, Kazunori Ono, Satoshi Kaimoto, Kuniyoshi Fukai,　Eri Iwai-Kanai, Satoaki Matoba
- Organizer
  American Heart Association Scientific Sessions 2015
- Place of Presentation
  Orlando, FL, USA
- Year and Date
  2015-11-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] クルクミンは、Jnkの活性化を抑制し、ドキソルビシン心筋障害を改善する2015
- Author(s)
  片村真紀　金井恵理　山中亮悦　波東大地　立石周平　大野数則　内橋基樹　深井邦剛1中岡幹彦　大川義文　有吉真　三田雄一郎　的場聖明
- Organizer
  第２４回　日本Cell Death学会
- Place of Presentation
  大阪
- Year and Date
  2015-07-11
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] 心臓超音波における左室拡張不全のスクリーニングに関する技術的検討2015
- Author(s)
  桑野和代　中村文彦　松尾収二　金井恵理
- Organizer
  第７９回日本循環器学会学術集会
- Place of Presentation
  大阪
- Year and Date
  2015-04-24
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] Therapeutic application of highly bioavailable curcumin for patients with cancer2014
- Author(s)
  Kanai M
- Organizer
  The 2nd International Conference on Pharma and Food
- Place of Presentation
  静岡
- Year and Date
  2014-11-05
- Invited
- Data Source
  KAKENHI-PROJECT-24590655
[Presentation] がん治療におけるクルクミンの可能性2014
- Author(s)
  金井　雅史
- Organizer
  第134年会日本薬学会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-24590655
[Presentation] A Phase I study of highly bioavailable curcumin (THERACURMIN ® ) in patients with refractory pancreatic or biliary tract cancer2013
- Author(s)
  Kanai M, Otsuka Y, Otsuka K, Sato M, Nishimura T, Mori Y, Kawaguchi M, Hatano E, Kodama Y, Matsumoto S, Murakami Y, Imaizumi A, Chiba T, Nishihira J, Shibata H.
- Organizer
  ASCO GI meeting
- Place of Presentation
  Sanfrancisco
- Data Source
  KAKENHI-PROJECT-24590655
[Presentation] がん治療におけるクルクミンの可能性2013
- Author(s)
  金井　雅史
- Organizer
  第9回日本食品免疫学会
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-24590655
[Presentation] ゲムシタビンに抵抗性となった膵癌・胆道癌患者に対するナノ化クルクミン療法の第I相臨床試験2012
- Author(s)
  金井　雅史、森　由希子、西村　貴文、松本　繁巳、柳原　一広、千葉　勉、波多野　悦朗、川口　義弥、児玉　裕三、西平　順、大塚　和令、柴田　浩行
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-24590655
[Presentation] ゲムシタビンによる皮疹とその対策2011
- Author(s)
  金井雅史
- Organizer
  第2回京都胆道カンファランス
- Place of Presentation
  京都
- Year and Date
  2011-01-13
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] 細粒化クルクミンを用いた新しいがん治療法の開発2011
- Author(s)
  金井雅史
- Organizer
  日本抗加齢医学会シンポジウム
- Place of Presentation
  京都
- Year and Date
  2011-05-27
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] クルクミンを用いた新しいがん治療法の開発2011
- Author(s)
  金井雅史、八隅秀二郎、千葉勉
- Organizer
  日本消化器病学会シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2011-10-16
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] クルクミンを用いた新規癌治療法の開発2010
- Author(s)
  金井雅史、八隅秀二郎、千葉勉
- Organizer
  日本消化器病学会
- Place of Presentation
  東京
- Year and Date
  2010-10-15
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] Pharmacogenetic approach to predicting clinical response of chemotherapy in advanced colorectal cancer2010
- Author(s)
  Kanai M
- Organizer
  Organisation for Oncology and Translational Research conference
- Place of Presentation
  Kyoto, Japan(招待講演)
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] A Phase I/II Study of Complementary Therapy Using Curcumin for Pancreatic Cancer Patients Who Get Refractory to Gemcitabine-Based Chemotherapy2010
- Author(s)
  Kanai M
- Organizer
  The 3rd World Cancer Congress 2010招待講演
- Place of Presentation
  Singapore
- Year and Date
  2010-06-23
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] A Phase I/II Study of Complementary Therapy Using Curcumin for Pancreatic Cancer Patients Who Get Refractory to Gemcitabine-Based Chemotherapy2010
- Author(s)
  Kanai M
- Organizer
  The 3^<rd> World Cancer Congress 2010
- Place of Presentation
  Singapore(招待講演)
- Year and Date
  2010-06-23
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] 切除不能進行胆道癌に対するゲムシタビン/S-1併用療法の治療成績2010
- Author(s)
  金井雅史
- Organizer
  第1回京都胆道カンファランス
- Place of Presentation
  京都
- Year and Date
  2010-06-10
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] A Phase I/II Study of Complementary Therapy Using Curcumin for Pancreatic Cancer Patients Who Get Refractory to Gemcitabine-Based Chemotherapy2010
- Author(s)
  Kanai M
- Organizer
  International Society for Nutraceuticals and Functional Food Annual Conference 2010招待講演
- Place of Presentation
  Indonesia
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] 切除不能胆道癌に対するgemcitabine+S-1併用療法の第II相臨床試験(最終結果)2010
- Author(s)
  金井雅史、波多野悦朗、津村剛彦、浅田全範、松本繁巳、西村貴文、濱田暁彦、井上直也、森由希子、吉村健一、柳原一広、多田真輔、八隅秀二郎、大崎往夫、千葉勉
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  東京
- Year and Date
  2010-03-18
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] Pharmacogenetic approach to predicting clinical response of chemotherapy in advanced colorectal cancer2010
- Author(s)
  Masashi Kanai
- Organizer
  Organisation for Oncology and Translational Research conference
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] A Phase I/II Study of Complementary Therapy Using Curcumin for Pancreatic Cancer Patients Who Get Resistant to Gemcitabine-Based Chemotherapy2010
- Author(s)
  Kanai M
- Organizer
  International Society for Nutraceuticals and Functional Foods Annual Conference 2010
- Place of Presentation
  Bali, Indonesia(招待講演)
- Year and Date
  2010-10-13
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] Pharmacogenetic approach to predicting clinical response of chemotherapy in advanced colorectal cancer2010
- Author(s)
  Kanai M
- Organizer
  Organisation for Oncology and Translational Research conference招待講演
- Place of Presentation
  Kyoto, Japan
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-21790661
[Presentation] Smoking history inhibits the incidence of neutropenia during gemcitabine monotherapy in cancer patients2009
- Author(s)
  Kanai M, Morita S, Matsumoto S, Nishimura T, Fukushima M
- Organizer
  Keystone Symposia
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2009-03-24
- Data Source
  KAKENHI-PROJECT-19790482
[Presentation] これからのがん医療を支える医療人をどう育成するか2008
- Author(s)
  柳原一広, 金井雅史, 石黒洋, 福島雅典
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋国際会議場・名古屋
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590511
[Presentation] これからのがん医療を支える医療人をどう育成するか2008
- Author(s)
  柳原一広、金井雅史、石黒洋、福島雅典
- Organizer
  第46回日本癌治療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-11-01
- Data Source
  KAKENHI-PROJECT-19590511
[Presentation] 進行・再発食道癌に対するセカンドライン化学療法としてのドセタキセル/ネダプラチン併用療法の治療成績2007
- Author(s)
  金井雅史, 松本繁巳, 西村貴文, 他
- Organizer
  日本臨床腫瘍学会
- Place of Presentation
  札幌
- Year and Date
  2007-03-24
- Data Source
  KAKENHI-PROJECT-19790482
[Presentation] The efficacy and safety of docetaxel/nedaplatin combination therapy as a second line regimen in advanced esophageal cancer2007
- Author(s)
  Kanai M, Matsumoto S, Nishimura T, Fukushima M
- Organizer
  ASCO Gastrointestinal Cancers Symposium
- Place of Presentation
  Orlando, USA
- Year and Date
  2007-01-19
- Data Source
  KAKENHI-PROJECT-19790482
[Presentation] Bdh1 Reduced Oxidative Stress and Cardiac Remodeling in Pressure Overload Heart Failure
- Author(s)
  Uchihashi M, Atsushi Hoshino, Makoto Ariyoshi, Shuhei Tateishi, Kazunori Ono, Satoshi Kaimoto, Kuniyoshi Fukai, Eri Kanai, Satoaki Matoba, iwai-kanai, E, Matoba S.
- Organizer
  The 79th Annual Scientific Meeting of Japanese Circulation Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] Activation of PPARα During the Progressive Phase of Heart Failure Improved Myocardial Energetics and Function in Pressure Overload Heart Failure
- Author(s)
  Satoshi Kaimoto, Atsushi Hoshino, Makoto Ariyoshi, Yoshifumi Okawa, Motoki Uchihashi, Kuniyoshi Fukai, Kazunori Ono, Shuhei Tateishi, Eri Iwai-Kanai, and Satoaki Matoba
- Organizer
  American Heart Association Scientific Sessions2014
- Place of Presentation
  Chicago, Illinois 60007, United States
- Year and Date
  2014-11-15 – 2014-11-19
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] The current guideline of pancreatic cancer in Japan
- Author(s)
  Kanai M
- Organizer
  Shanghai International Conference on Pancreatic Cancer
- Place of Presentation
  Shanghai
- Year and Date
  2014-08-01 – 2014-08-03
- Invited
- Data Source
  KAKENHI-PROJECT-24590655
[Presentation] Oxidative Post-translational Modification of Lon Protease Homolog (LONP1) Contributes to the Development of Heart Failure
- Author(s)
  Matoba S Atsushi Hoshino, Yoshifumi Ohkawa, Makoto Ariyoshi, Satoshi Kaimoto, Motoki Uchihashi, Kuniyoshi Fukai, Eri Iwai-Kanai
- Organizer
  The 79th Annual Scientific Meeting of Japanese Circulation Society
- Place of Presentation
  Osaka, Japan
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-26460350
[Presentation] 心臓超音波における左室拡張不全のスクリーニングに関する技術的検討
- Author(s)
  桑野和代、中村文彦, 松尾収二, 金井恵理
- Organizer
  第７９回日本循環器学会
- Place of Presentation
  大阪、日本
- Year and Date
  2015-04-24 – 2015-04-26
- Data Source
  KAKENHI-PROJECT-26460350

1. MATSUDA Fumihiko (50212220)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. Iwai-Kanai Eri (20372584)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
3. YANAGIHARA Kazuhiro (70332731)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. NISHIMURA Takafumi (40378732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. FUKUSHIMA Masanori (80107820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. ISHIGURO Hiroshi (20422925)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. MISAWA Akiko (10378755)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. YASUDA Hiroyasu (90396482)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. HIRAIDE Atsushi (20199037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 村上善基 (00397556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. 的場聖明 (10305576)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
12. MATSUMOTO Shigemi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KITANO Toshiyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 三田雄一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
15. 石原直忠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kanai Masashi 金井 雅史

KANAI MASASHI 金井 雅史

KANAI Masashi 金井 雅史

Research Projects

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Co-Researchers

オキサリプラチンの至適投与法に関する研究Principal Investigator

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Development of precision medicine for patients with pancreatic cancer who harbor homologous recombinant repair genesPrincipal Investigator

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Research for heart protection during cancer chemotherapy via regulating cardiac autophagy

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Investigation of a novel anti-cancer effects of curcumin using comprehensive miRNA expression analysisPrincipal Investigator

Principal Investigator

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Pharmacogenetic study to predicting clinical response of oxaliplatin in patients with advanced colorectal cancerPrincipal Investigator

Principal Investigator

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Educational system of oncology

Principal Investigator

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Pharmacogenetic analysis of clinical response to oxaliplatin-based Chemotherapy in colorectal cancer patientsPrincipal Investigator

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[Book] 肝と膵2019

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[Book] 分子消化器病(遺伝子多型解析は消化器癌化学療法にどのように役に立つのか?)2011

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[Book] 分子消化器病「消化器癌治療薬選択のための遺伝子検査」2010

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[Book] 外科治療(胆道癌補助化学療法の実際)第102号2010

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[Book] 分子消化器病(消化器癌治療薬選択のための遺伝子検査)7巻4号2010

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[Book] 伏見医報(分子標的薬剤を用いた消化器がん化学療法の現状)6072010

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[Book] 最近の消化器癌化学療法の進歩-大腸癌化学療法を中心に, 西宮医師会雑誌第14号2009

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[Book] 臨床消化器内科2008

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Kanai Masashi 金井雅史

KANAI MASASHI 金井雅史

KANAI Masashi 金井雅史

[Journal Article] Curcumin attenuates doxorubicin-induced cardiotoxicity by inducing autophagy via the　regulation of JNK phosphorylation2014