Ito Sachiko 伊藤佐知子

… Alternative Names

伊藤佐知子イトウサチコ

ITO Sachiko 伊藤佐知子

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Researcher Number	70447845
Other IDs
Affiliation (Current)	2025: 名古屋大学, 医学系研究科, 講師
Affiliation (based on the past Project Information) *help	2025: 名古屋大学, 医学系研究科, 講師 2022 – 2023: 名古屋大学, 医学系研究科, 講師 2016 – 2017: 名古屋大学, 医学系研究科, 講師 2016: 名古屋大学, 医学(系)研究科(研究院), 助教 2015 – 2016: 名古屋大学, 医学(系)研究科(研究院), 講師 … More 2011 – 2014: 名古屋大学, 医学(系)研究科(研究院), 助教 2010 – 2011: 名古屋大学, 医学系研究科, 助教 2008: Nagoya University, 大学院・医学系研究科, COE特任助教 2008: Nagoya University, 大学院・医学系研究科, COE特任教授 2007: Nagoya University, 大学院・医学研究科, 助教 2007: 名古屋大学, 環境医学研究所, 研究員 Less
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Applied health science / Applied health science / Neurochemistry/Neuropharmacology Except Principal Investigator General internal medicine(including psychosomatic medicine) / Cerebral neurosurgery
Keywords	Principal Investigator GADD34 / 免疫チェックポイント阻害剤 / ERストレス / 炎症 / マクロファージ / 創傷治癒 / シグナル伝達 / 腫瘍免疫 / がん免疫 / 代謝 … More / 酸化ストレス / がん免疫応答 / 大腸癌 / MDSCs / 腫瘍形成 / 低酸素ストレス / 炎症関連大腸癌 / TLR4シグナル / 細胞ストレス / 細胞増殖 / オートファージー / ストレス / ストレス応答 / 栄養欠乏 / アポトーシス / オートファジー / 栄養制御 / 老化 / TORシグナル伝達系 / 栄養欠乏ストレス / 絶食ストレス / mTORシグナル / 神経科学 / アミロイドβ / ミクログリア / 神経生物学 … More Except Principal Investigator 再生 / 免疫 / 生活習慣病 / ストレス / メタボリックシンドローム / インスリンシグナル / 脂肪肝 / ２型糖尿病 / ERストレス / GADD34 / 老化 / 脳種瘍 / ミクログリア / オートファジー / 脳腫瘍 Less

がんの遺伝子発現変化に伴う抗腫瘍免疫応答減弱の克服に向けたメカニズムの解明Principal Investigator
- Principal Investigator
  
  伊藤佐知子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagoya University
がん免疫療法の治療抵抗性に関わる遺伝子変異による抗腫瘍免疫応答減弱機構の解明Principal Investigator
- Principal Investigator
  
  伊藤佐知子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Nagoya University
Analysis of the function of GADD34 in innate immune response and inflammation-induced colon cancerPrincipal Investigator
- Principal Investigator
  
  Ito Sachiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Nagoya University
Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCs
- Principal Investigator
  
  isobe ken-ichi
- Project Period (FY)
  2013 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General internal medicine(including psychosomatic medicine)
- Research Institution
  Nagoya Women's University
  Nagoya University
Analysis of the function of GADD34 in cell growth, migration and starvation-stress responsePrincipal Investigator
- Principal Investigator
  
  Ito Sachiko
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied health science
- Research Institution
  Nagoya University
Analysis of GADD34 function in aging, nutrient control and wound healingPrincipal Investigator
- Principal Investigator
  
  ITO Sachiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  Nagoya University
ミクログリアによる悪性脳腫瘍とオートファジーの制御
- Principal Investigator
  
  神澤孝夫
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Institute of Brain and Blood Vessels
  Nagoya University
Cloning of Aβ-binding membrane protein in microglia by using SST-REX methodPrincipal Investigator
- Principal Investigator
  
  ITO Sachiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Nagoya University

All 2016 2015 2014 2013 2012 2011 2010 2009 2008 Other

All Journal Article Presentation

[Journal Article] Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils.2016
- Author(s)
  Tanaka Y, Ito S, Isobe K.
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Issue: 1 Pages: 23920-23920
- DOI
  10.1038/srep23920
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05280, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-15K01708
[Journal Article] GADD34 Promotes Tumor Growth by Inducing Myeloid-derived Suppressor Cells.2016
- Author(s)
  Liu L, Ito S, Nishio N, Sun Y, Tanaka Y, Isobe K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 36 Pages: 4623-4628
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K01708
[Journal Article] GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation.2016
- Author(s)
  Ito S, Tanaka Y, Oshino R, Okado S, Hori M, Isobe KI.
- Journal Title
  
  Cell Death Dis.
  
  Volume: 7 Issue: 5 Pages: e2219-e2219
- DOI
  10.1038/cddis.2016.116
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16H05280, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-15K01708
[Journal Article] Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice.2016
- Author(s)
  Du Q, Tsuboi N, Shi Y, Ito S, Sugiyama Y, Furuhashi K, Endo N, Kim H, Katsuno T, Akiyama S, Matsuo S, Isobe KI, Maruyama S.
- Journal Title
  
  Am J Pathol.
  
  Volume: 186 Issue: 12 Pages: 3176-3188
- DOI
  10.1016/j.ajpath.2016.08.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-15K09256, KAKENHI-PROJECT-16K09611
[Journal Article] GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition2015
- Author(s)
  Liu L, Ito S, Nishio N, Sun Y, Chen N, Tanaka Y, Isobe K
- Journal Title
  
  Anticancer Res.
  
  Volume: 35 Pages: 5317-5324
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K01708
[Journal Article] GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition.2015
- Author(s)
  Liu L, Ito S, Nishio N, Sun Y, Chen N, Tanaka Y, Isobe K.
- Journal Title
  
  Anticancer Res.
  
  Volume: 35(10) Pages: 5317-5324
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293166
[Journal Article] Recruitment of Gr1(+)CD11b (+)F4/80 (+) Population in the Bone Marrow and Spleen by Irradiation-Induced Pulmonary Damage.2015
- Author(s)
  Thanasegaran S, Ito S, Nishio N, Uddin MN, Sun Y, Isobe K.
- Journal Title
  
  Inflammation
  
  Volume: 38 Issue: 2 Pages: 465-475
- DOI
  10.1007/s10753-014-9952-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-26870257
[Journal Article] Angioblast derived from ES cells construct blood vessels and ameliorate diabetic polyneuropathy in mice.2015
- Author(s)
  Himeno T
- Journal Title
  
  Journal of Diabetes Research
  
  Volume: 2015 Pages: 257230-257230
- DOI
  10.1155/2015/257230
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25293144, KAKENHI-PROJECT-25293166
[Journal Article] Effects of growth arrest and DNA damage-inducible protein 34 (GADD34) on inflammation-induced colon cancer in mice2015
- Author(s)
  Tanaka Y, Ito S, Oshino R, Chen N, Nishio N, Isobe K.
- Journal Title
  
  Br J Cancer.
  
  Volume: 113 Issue: 4 Pages: 669-679
- DOI
  10.1038/bjc.2015.263
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01708, KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition2015
- Author(s)
  Liu L, Ito S, Nishio N, Sun Y, Chen N, Tanaka Y, Isobe K
- Journal Title
  
  Anticancer Res.
  
  Volume: 35 Pages: 5317-5324
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500852
[Journal Article] Thymic Epithelial Cells Induced from Pluripotent Stem Cells by a Three-Dimensional Spheroid Culture System Regenerates Functional T Cells in Nude Mice.2015
- Author(s)
  41. Okabe Motohito, Sachiko Ito, Naomi Nishio, Yuriko Tanaka and Ken-ichi Isobe
- Journal Title
  
  Cell Reprogramming
  
  Volume: 17(5) Issue: 5 Pages: 368-375
- DOI
  10.1089/cell.2015.0006
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-25293166
[Journal Article] Growth arrest and DNA damage-inducible protein (GADD34) enhanced liver inflammation and tumorigenesis in a diethylnitrosamine (DEN)-treated murine model.2015
- Author(s)
  Chen N, Nishio N, Ito S, Tanaka Y, Sun Y, Isobe K.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: 64 Issue: 6 Pages: 777-789
- DOI
  10.1007/s00262-015-1690-8
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K01708, KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy2015
- Author(s)
  Ito S, Tanaka Y, Oshino R, Aiba K, Thanasegaran S, Nishio N, Isobe K
- Journal Title
  
  Scientific Reports
  
  Volume: 5 Issue: 1 Pages: 8327-8327
- DOI
  10.1038/srep08327
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257
[Journal Article] Acrolein induced both pulmonary inflammation and the death of lung epithelial cells.2014
- Author(s)
  Sun Y, Ito S, Nishio N, Tanaka Y, Chen N, Isobe K.
- Journal Title
  
  Toxicol Lett.
  
  Volume: 229 Issue: 2 Pages: 384-392
- DOI
  10.1016/j.toxlet.2014.06.021
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-26870257
[Journal Article] iPSCs, aging and age-related diseases.2014
- Author(s)
  Isobe K, Cheng Z, Nishio N, Suganya T, Tanaka Y, Ito S.
- Journal Title
  
  N Biotechnol
  
  Volume: 31 Issue: 5 Pages: 411-421
- DOI
  10.1016/j.nbt.2014.04.004
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257
[Journal Article] Negative regulation of GADD34 on myofibroblasts during cutaneous wound healing.2014
- Author(s)
  Liu L, Nishio N, Ito S, Tanaka Y, Isobe K.
- Journal Title
  
  Biomed Res Int
  
  Volume: 2014 Pages: 137049-137049
- DOI
  10.1155/2014/137049
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257
[Journal Article] Acrolein induced both pulmonary inflammation and the death of lung epithelial cells2014
- Author(s)
  Sun Y, Ito S, Nishio N, Tanaka Y, Chen N, Isobe K.
- Journal Title
  
  Toxicol Lett.
  
  Volume: 229 Pages: 384-392
- DOI
  10.1155/2015/170309
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-26870257, KAKENHI-PROJECT-15K01708, KAKENHI-PROJECT-24500852
[Journal Article] iPS cell sheets created by a novel magnetite tissue engineering method for reparative angiogenesis.2013
- Author(s)
  Kito T, Shibata R, Ishii M, Suzuki H, Himeno T, Kataoka Y, Yamamura Y, Yamamoto T, Nishio N, Ito S, Numaguchi Y, Tanigawa T, Yamashita JK, Ouchi N, Honda H, Isobe K, Murohara T.
- Journal Title
  
  Sci Rep
  
  Volume: 11:3 Issue: 1 Pages: 1418-1418
- DOI
  10.1038/srep01418
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144, KAKENHI-PROJECT-23390207, KAKENHI-PROJECT-23390208, KAKENHI-PROJECT-23790845, KAKENHI-PROJECT-24659384, KAKENHI-PROJECT-25293166, KAKENHI-PROJECT-25860595
[Journal Article] Characteristics of cardiac aging in C57BL/6 mice.2013
- Author(s)
  Cheng Z, Ito S, Nishio N, Thanasegaran S, Fang H, Isobe K.
- Journal Title
  
  Exp Gerontol
  
  Volume: 48(3) Issue: 3 Pages: 341-348
- DOI
  10.1016/j.exger.2013.01.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144, KAKENHI-PROJECT-25293166
[Journal Article] Mesenchymal stem cell-like cells derived from mouse induced pluripotent stem cells ameliorate diabetic polyneuropathy in mice.2013
- Author(s)
  Himeno T, Kamiya H, Naruse K, Cheng Z, Ito S, Kondo M, Okawa T, Fujiya A, Kato J, Suzuki H, Kito T, Hamada Y, Oiso Y, Isobe K, Nakamura J.
- Journal Title
  
  Biomed Res Int
  
  Volume: - Pages: 259187-259187
- DOI
  10.1155/2013/259187
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23591303, KAKENHI-PROJECT-25293166
[Journal Article] Loss of GADD34 induces early age-dependent deviation to the myeloid lineage.2013
- Author(s)
  Nishio N, Ito S, Isobe K.
- Journal Title
  
  Immunol Cell Biol.
  
  Volume: 92 Issue: 2 Pages: 170-80
- DOI
  10.1038/icb.2013.78
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] No immunogenicity of IPS cells in syngeneic host studied by in vivo injection and 3D scaffold experiments.2013
- Author(s)
  Thanasegaran S, Cheng Z, Ito S, Nishio N, Isobe K.
- Journal Title
  
  Biomed Res Int.
  
  Volume: 2013 Pages: 378207-378213
- DOI
  10.1155/2013/378207
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] Establishment of self-renewable GM-CSF-dependent immature macrophages in vitro from murine bone marrow.2013
- Author(s)
  Ito S, Tanaka Y, Nishio N, Thanasegaran S, Isobe K.
- Journal Title
  
  PLoS One.
  
  Volume: 8 Issue: 10 Pages: e76943-e76943
- DOI
  10.1371/journal.pone.0076943
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24500852, KAKENHI-PROJECT-25293166
[Journal Article] Autophagic activity in thymus and liver during aging.2012
- Author(s)
  Uddin MN
- Journal Title
  
  Age(Dordr)
  
  Volume: 34(1) Issue: 1 Pages: 75-85
- DOI
  10.1007/s11357-011-9221-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390144, KAKENHI-PROJECT-22700691
[Journal Article] Gadd34 induces autophagy through the suppression of the mTOR pathway during starvation2011
- Author(s)
  Uddin MN, Ito S, Nishio N, Suganya T, Isobe K
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 407(4) Issue: 4 Pages: 692-8
- DOI
  10.1016/j.bbrc.2011.03.077
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700691
[Journal Article] GADD34 suppresses wound healing by upregulating expression of myosin IIA2010
- Author(s)
  Tanaka C, Ito S, Nishio N, Kodera Y, Sakurai H, Suzuki H, Nakao A, Isobe K
- Journal Title
  
  Transgenic Res
  
  Volume: 19(4) Issue: 4 Pages: 637-45
- DOI
  10.1007/s11248-009-9347-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22700691
[Journal Article] Age-related decline of immune function and age-related diseases2009
- Author(s)
  Ken-ichi Isobe, Naomi Nishio, Sachiko Ito
- Journal Title
  
  Nihon Rinsyo in press
- NAID
  40016709041
- Data Source
  KAKENHI-PROJECT-19700340
[Journal Article] Inhibition of reactive oxygen species down-regulates protein synthesis in RAW 264.7.2008
- Author(s)
  Kimura K, Ito S, Nagino M, Isobe K
- Journal Title
  
  Biochem Biophys Res Commun 372(1)
  
  Pages: 272-275
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19700340
[Presentation] Therapeutic effects of antibiotics on colitis and colon carcinogenesis in AOM/DSS-induced murine colitis-associated colon cancer model2015
- Author(s)
  Tanaka Y, Ito S, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Therapeutic effects of antibiotics on colitiss and colon carcinogensis in AOM/DSS-induced murine colitiss-associated colon cancer model.2015
- Author(s)
  Tanaka Y, Ito S, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター　北海道、札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 promotes colon carcinogenesis through upregulating IL-6-STAT3 signaling2015
- Author(s)
  Ito S, Tanaka Y, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター（北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GADD34 promotes colon carcinogensis through upregulating IL-6-STAT3 signaling.2015
- Author(s)
  Ito S, Tanaka Y, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター　北海道、札幌市
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 promotes colon carcinogenesis through upregulating IL-6-STAT3 signaling2015
- Author(s)
  Ito S, Tanaka Y, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K01708
[Presentation] Therapeutic effects of antibiotics on colitis and colon carcinogenesis in AOM/DSS-induced murine colitis-associated colon cancer model2015
- Author(s)
  Tanaka Y, Ito S, Isobe K.
- Organizer
  第44回日本免疫学会学術総会
- Place of Presentation
  札幌コンベンションセンター(北海道札幌市）
- Year and Date
  2015-11-18
- Data Source
  KAKENHI-PROJECT-15K01708
[Presentation] ストレス応答遺伝子GADD34はマウス炎症関連大腸癌モデルにおいて炎症・発癌を促進する2015
- Author(s)
  田中ゆりこ, 伊藤佐知子, 磯部健一
- Organizer
  第38回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド (兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] ストレス応答遺伝子GADD34はマウス炎症関連大腸癌モデルにおいて炎症・発癌を促進する2015
- Author(s)
  田中ゆりこ、伊藤佐知子、磯部健一
- Organizer
  第38回分子生物学会年会
- Place of Presentation
  神戸ポートアイランド(兵庫県神戸市）
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K01708
[Presentation] Acrolein-induced lung cell death and macrophages functional changes.2014
- Author(s)
  Sun Yang,Sachiko Ito, Yuriko Tanaka, Lintao Liu, Nana Chin, Naomi Nishioand Ken-ichi Isobe
- Organizer
  The japanese-Korean Lymphoreticular workshop 2014 in conjunction with the 5th Asian Hematopathology symposium
- Place of Presentation
  名古屋大学附属病院(名古屋市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Injection of GR-1+CD11ｂ+ cells to inflammation-induced colon cancer reduces tumor formation2014
- Author(s)
  Yutriko Tanaka, Sachiko Ito, Reina Oshino, Naomi Nishio, Ken-ichi Isobe
- Organizer
  The japanese-Korean Lymphoreticular workshop 2014 in conjunction with the 5th Asian Hematopathology symposium
- Place of Presentation
  名古屋大学附属病院(名古屋市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Negative Regulation of GADD34 on Myofibroblasts during Cutaneous Wound Healing2013
- Author(s)
  Lintao Liu, Naomi Nishio,Sachiko Ito, Yuriko Tanaka and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Negative regulation of GADD34 on mofibroblasts during cutaneous wound healing2013
- Author(s)
  Liu L., Nishio N., Ito S., Tanaka Y.,Isobe K.
- Organizer
  Annual Meeting of the Japanese of Society for Immunology, 2013
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GADD34は高脂肪食による脂肪蓄積を予防する2013
- Author(s)
  西尾尚美, 伊藤佐知子、磯部　健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪大学中之島センター、大阪国際会議場（大阪市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GM-CSF依存的に長期増殖するマウス骨髄由来マクロファージ細胞の解析２2013
- Author(s)
  伊藤佐知子、田中ゆりこ、西尾尚美、Zhao Cheng、磯部健一
- Organizer
  第36回　日本基礎老化学会
- Place of Presentation
  大阪国際会議場（大阪市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Acrolein-induced lung cell death and macrophages functional changes2013
- Author(s)
  Sun Y., Ito S., Tanaka Y., Nihiso N., Isobe K.
- Organizer
  Annual Meeting of the Japanese of Society for Immunology, 2013
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GM－CSF依存的に長期増殖するマウス骨髄由来マクロファージ細胞の解析２2013
- Author(s)
  伊藤佐知子、田中ゆりこ、西尾尚美、Cheng Zhao, 磯部健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪大学中之島センター、大阪国際会議場(大阪市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Establishment of macrophage stem-like cells from murine bone marrow2013
- Author(s)
  Ito S., Tanaka Y., Nishio N., Oshino R., Isobe K.
- Organizer
  Annual Meeting of the Japanese of Society for Immunology, 2013
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] The role of macrophages in tumorigenesis.2013
- Author(s)
  Yuriko　TANAKA,, Sachiko Ito, Naomi Nishio and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34は高脂肪食による脂肪蓄積を予防する2013
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第36回　日本基礎老化学会
- Place of Presentation
  大阪国際会議場（大阪市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Establishment of macrophage stem-like cells from murine bone marrow2013
- Author(s)
  Sachiko Ito, Naomi Nishio,Yuriko Tanaka and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Loss of GAD34 induces fatty liver diseased, type II diabetes2013
- Author(s)
  Nishio N., Ito S., Isobe K.
- Organizer
  Annual Meeting of the Japanese of Society for Immunology, 2013
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Acrolein-induced lung cell death and macrophages functional changes2013
- Author(s)
  Yang Sun,, Sachiko Ito, Yuriko Tanaka, Naomi Nishio and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Loss of GADD34 induces fatty liver diseases, type II Diabetes2013
- Author(s)
  NISHIO Naomi,Sachiko Ito and Ken-ichi Isobe
- Organizer
  第42回日本免疫学会
- Place of Presentation
  幕張メッセ(千葉市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] iPS細胞の免疫原生とaging2013
- Author(s)
  Thanasegaran Suganya、, Zhao Cheng, 伊藤佐知子、西尾直美、磯部　健一
- Organizer
  第36回日本基礎老化学会
- Place of Presentation
  大阪大学中之島センター、大阪国際会議場(大阪市）
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] The roles of macrophages in colon tumorigenesis2013
- Author(s)
  Tanaka Y., Ito S., Nishio N., Oshino R., Isobe K.
- Organizer
  Annual Meeting of the Japanese of Society for Immunology, 2013
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GM-CSF依存的に長期増殖するマウス骨髄由来マクロファージの解析2012
- Author(s)
  伊藤佐知子、田中ゆりこ、西尾尚美、磯部健一
- Organizer
  第35回日本基礎老化学会
- Place of Presentation
  千葉県船橋・東邦大学
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Loss of GAD34 induces early immune aging: impact on the proliferation of neutrophil-linage cells.2012
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GADD34は免疫老化を抑制する。骨髄好中球前駆細胞の増殖抑制2012
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第35回日本基礎老化学会
- Place of Presentation
  千葉県船橋・東邦大学
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] The expression of GADD34 is induced by various TLR ligands and affects the cytokine productions via TLR signaling2012
- Author(s)
  伊藤佐知子、西尾尚美、田中ゆりこ、磯部健一
- Organizer
  第41回日本免疫学会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GADD34 regulates the LPS-induced cytokine production via TSC-mTOR signaling pathway2011
- Author(s)
  伊藤佐知子、西尾尚美、鈴木治彦、磯部健一
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] GADD34遺伝子欠損マウスは老化に伴いミエロ系細胞が異常増殖する2011
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第34回日本基礎老化学会
- Place of Presentation
  東京
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] The loss of GAD34 gene induced the abnormal expansion of neutrophil2011
- Author(s)
  西尾尚美、伊藤佐知子、鈴木治彦、磯部健一
- Organizer
  第40回日本免疫学会総会
- Place of Presentation
  千葉
- Year and Date
  2011-11-27
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] GADD34 regulates the LPS-induced cytokine production via TSC-mTOR signaling pathway.2011
- Author(s)
  伊藤佐知子
- Organizer
  第40回　日本免疫学会総会
- Place of Presentation
  千葉、幕張メッセ
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] マウス骨髄由来樹状細胞における GADD34 の役割と老化との関連2010
- Author(s)
  伊藤佐知子、西尾尚美、磯部健一
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] マウス骨髄由来樹状細胞におけるGADD34の役割と老化の関連2010
- Author(s)
  伊藤佐知子
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  野依記念学術交流会館(名古屋大学、名古屋市)
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] GADD34の生体内機能と老化への関与2010
- Author(s)
  西尾尚美、伊藤佐知子、磯部健一
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] 磯部健一胸腺の老化と胸腺上皮細胞の変化2010
- Author(s)
  Mohammad NizamUddin、伊藤佐知子、西尾尚美、Zhao Cheng 、Zhang Rong
- Organizer
  第33回日本基礎老化学会
- Place of Presentation
  名古屋
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22700691
[Presentation] Amyloid-β刺激によるミクログリア活性化と炎症性物質の産生2008
- Author(s)
  伊藤佐知子、磯部健一
- Organizer
  第31回日本基礎老化学会
- Place of Presentation
  松本、日本
- Year and Date
  2008-06-13
- Data Source
  KAKENHI-PROJECT-19700340
[Presentation] Murine model of age-related COPD and lung defense system.
- Author(s)
  Sun Y, Ito S, Chen N, Tanaka Y, Liu L, Nishio N, Isobe K.
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works tossups obesity-induced non alcoholic steatohepatitis (NASH) by regulation of insulin/IGF signaling.
- Author(s)
  Nishio N, Ito S, Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] The effects of GADD34 on LPS stimulation in mice
- Author(s)
  Oshino R, Ito S, Tanaka Y, Nishio N, Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] The effects of GADD34 on LPS stimulation in mice.
- Author(s)
  Oshino R, Ito S, Tanaka Y, Nishio N, Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to　 suppress obesity-induced non alcoholic steatohepatitis (NASH) by regulation of insulin/IGF signaling.
- Author(s)
  Nishio N, Ito S, Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] The involvement of growth arrest and DNA damage-inducible protein (GADD34) in the tumorigenesis of hepatocellular carcinoma
- Author(s)
  Chen N, Nishio N, Ito S, Sun Y, Tanaka Y, Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 promotes colon inflammation and tumorigenesis
- Author(s)
  Tanaka Y Ito S, Oshino R, Nishio N Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Establishment of macrophage stem-like cells from murine yolk sac.
- Author(s)
  Ito S, Oshino R Tanaka Y, Nishio N Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to suppress obesity-induced metabolic diseases including type 2 diabetes and NASH.
- Author(s)
  Nishio N, Ito S, Isobe K.
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町））
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 promotes colon inflammation and tumorigenesis
- Author(s)
  Tanaka Y Ito S, Oshino R, Nishio N Isobe K.
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府、京都市））
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Murine model experiments of stem cell therapy to age-related infectious diseases
- Author(s)
  Chen N, Ito S, Cheng Z,
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] GADD34 works to suppress obesity-induced metabolic diseases including type 2 diabetes and NASH
- Author(s)
  Nishio Naomi, Ito Sachiko, Isobe Ken-ichi
- Organizer
  日本基礎老化学会第37回大会
- Place of Presentation
  あいち健康プラザ（愛知県知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
- Author(s)
  Ito Sachiko, Tanaka Yuriko, Thanasegaran Suganya Oshino Reina, Nishio Naomi, Isobe Ken-ichi,
- Organizer
  日本基礎老化学会第37回大会
- Place of Presentation
  あいち健康プラザ（愛知県知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] GADD34 inhibits activation-induced apoptosis of macrophages through enhancement of autophagy
- Author(s)
  Ito S, Tanaka Y, Thanasegaran S, Oshino R, Nishio
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] Effects of GADD34 to TLR signaling
- Author(s)
  Tanaka Yuriko, Ito Sachiko, Oshino Reina, Nishio Naomi, Isobe Ken-ichi
- Organizer
  日本基礎老化学会第37回大会
- Place of Presentation
  あいち健康プラザ（愛知県知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Murine model of age-related COPD and lung defense system.
- Author(s)
  Yang Sun, Ito Sachiko, Chen Nana, Tanaka Yuriko, Liu Lintao, Nishio Naomi, Isobe Ken-ichi
- Organizer
  日本基礎老化学会第37回大会
- Place of Presentation
  あいち健康プラザ（愛知県知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Establishment of macrophage stem-like cells from murine yolk sac
- Author(s)
  Ito S, Oshino R Tanaka Y, Nishio N Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Murine model experiments of stem cell therapy to age-related infectious diseases
- Author(s)
  Chen Nana, Ito Sachiko, Cheng Zhao, THanasegaran Suganaya, Yang Sun, Nishio Naomi, Isobe Ken-ichi
- Organizer
  日本基礎老化学会第37回大会
- Place of Presentation
  あいち健康プラザ（愛知県知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-24500852
[Presentation] Effects of GADD34 to TLR signaling
- Author(s)
  Tanaka Y, Ito S, Oshino R, Nishio N Isobe K.
- Organizer
  第37回日本基礎老化学会大会
- Place of Presentation
  あいち健康プラザ　健康科学館（愛知県、知多郡東浦町）
- Year and Date
  2014-06-26 – 2014-06-27
- Data Source
  KAKENHI-PROJECT-25293166
[Presentation] The involvement of growth arrest and DNA damage-inducible protein (GADD34) in the tumorigenesis of hepatocellular carcinoma
- Author(s)
  Chen N, Nishio N, Ito S, Sun Y, Tanaka Y, Isobe K
- Organizer
  第43回日本免疫学会学術総会
- Place of Presentation
  国立京都国際会館（京都府京都市）
- Year and Date
  2014-12-10 – 2014-12-12
- Data Source
  KAKENHI-PROJECT-24500852

1. isobe ken-ichi (20151441)

# of Collaborated Projects: 1 results

# of Collaborated Products: 28 results
2. 神澤孝夫 (60447844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 澤田誠 (10187297)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 祖父江元 (20148315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 大橋憲太郎 (50332953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 西尾尚美 (80513457)

# of Collaborated Projects: 1 results

# of Collaborated Products: 22 results
7. 長谷川忠男 (10314014)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SHIBATA Rei

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 室慶直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 成瀬桂子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 中村二郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 神谷英紀

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ito Sachiko 伊藤 佐知子

伊藤 佐知子 イトウ サチコ

ITO Sachiko 伊藤 佐知子

Research Projects

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Co-Researchers

がんの遺伝子発現変化に伴う抗腫瘍免疫応答減弱の克服に向けたメカニズムの解明Principal Investigator

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がん免疫療法の治療抵抗性に関わる遺伝子変異による抗腫瘍免疫応答減弱機構の解明Principal Investigator

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Analysis of the function of GADD34 in innate immune response and inflammation-induced colon cancerPrincipal Investigator

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Age-related diseases analyzed by ER stresses and immune functions using murine models including iPSCs

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Analysis of the function of GADD34 in cell growth, migration and starvation-stress responsePrincipal Investigator

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Analysis of GADD34 function in aging, nutrient control and wound healingPrincipal Investigator

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ミクログリアによる悪性脳腫瘍とオートファジーの制御

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Cloning of Aβ-binding membrane protein in microglia by using SST-REX methodPrincipal Investigator

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[Journal Article] Vancomycin-sensitive bacteria trigger development of colitis-associated colon cancer by attracting neutrophils.2016

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[Journal Article] GADD34 Promotes Tumor Growth by Inducing Myeloid-derived Suppressor Cells.2016

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[Journal Article] GADD34 suppresses lipopolysaccharide-induced sepsis and tissue injury through the regulation of macrophage activation.2016

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[Journal Article] Transfusion of CD206+ M2 Macrophages Ameliorates Antibody-Mediated Glomerulonephritis in Mice.2016

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[Journal Article] GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition2015

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[Journal Article] GADD34 Facilitates Cell Death Resulting from Proteasome Inhibition.2015

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Ito Sachiko 伊藤佐知子

伊藤佐知子イトウサチコ

ITO Sachiko 伊藤佐知子