Ogawa Tomohiro 小川智弘

… Alternative Names

OGAWA Tomohiro 小川智弘

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Researcher Number	70448752
Affiliation (Current)	2025: 近畿大学, 工学部, 准教授
Affiliation (based on the past Project Information) *help	2014 – 2015: 近畿大学, 工学部, 講師 2011: 大阪市立大学, 大学院・医学研究科, 博士研究員 2011: 近畿大学, 工学部, 助教 2010: 大阪市立大学, 大学院・医学研究科, ポスドク研究員 2009 – 2010: 大阪市立大学, 大学院・医学研究科, 研究員
Review Section/Research Field	Principal Investigator General anatomy (including histology/embryology) / Gastroenterology Except Principal Investigator Carcinogenesis / Gastroenterology
Keywords	Principal Investigator コラーゲン / 肝臓 / 星細胞 / 線維化 / オステオポンチン / インテグリン / マイクロRNA Except Principal Investigator ビタミンA / 線維芽細胞 / サイトグロビン … More / 間質細胞 / 自然発症 / 乳癌 / ジエチルニトロサミン / サイトグロイン / ジェチルニトロサミン / 動物モデル / 肝癌 / 肝硬変 Less

Study on the molecular mechanisms of fibrogenesis by myofibroblasts which accumulate around fibersPrincipal Investigator
- Principal Investigator
  
  OGAWA Tomohiro
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General anatomy (including histology/embryology)
- Research Institution
  Kinki University
Involvement of cytoglobin-expressing mesenchymal cells in cancer development
- Principal Investigator
  
  KAWADA Norifumi
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Carcinogenesis
- Research Institution
  Osaka City University
Development of liver fibrosis therapy targeting hepatic stellate cells by microRNAPrincipal Investigator
- Principal Investigator
  
  OGAWA Tomohiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kinki University
  Osaka City University
Analyses of the development of liver cancer and cirrhosis by using cytoglobin-deficient mice
- Principal Investigator
  
  KAWADA Norifumi
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Osaka City University

All 2015 2012 2011 2010

All Journal Article Presentation Patent

[Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis.2012
- Author(s)
  Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N.
- Journal Title
  
  Gut
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis2012
- Author(s)
  Ogawa T, Enomoto M, Fujii H, Sekiya Y, Yoshizato K, Ikeda K, Kawada N
- Journal Title
  
  Gut
  
  Volume: (in press)
- Data Source
  KAKENHI-PROJECT-22650224
[Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis2012
- Author(s)
  小川智弘
- Journal Title
  
  Gut
  
  Volume: (掲載確定) Issue: 11 Pages: 1600-1609
- DOI
  10.1136/gutjnl-2011-300717
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790666
[Journal Article] microRNA-221/222 up-regulation indicates the activation of stellate cells and the progression of liver fibrosis2012
- Author(s)
  Ogawa T, Enomoto M, Fujii H他4名
- Journal Title
  
  Gut
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790666
[Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011
- Author(s)
  Sekiya Y, Ogawa T, Iizuka M, Yoshizato K, Ikeda K, Kawada N.
- Journal Title
  
  J Cell Physiol
  
  Volume: 226 Pages: 2535-42
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] Down-regulation of cyclin E1 expression by microrna-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011
- Author(s)
  Sekiya Y, Ogawa T, Iizuka M他3名
- Journal Title
  
  J Cell Physiol
  
  Volume: 226(10) Pages: 2535-2542
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790666
[Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Thuy le TT2011
- Author(s)
  Morita T, Yoshida K, Wakasa K, Iizuka M, Ogawa T, Mori M, Sekiya Y, Momen S, Motoyama H, Ikeda K, Yoshizato K, Kawada N.
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 1050-60
- Data Source
  KAKENHI-PROJECT-22650224
[Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Thuy le TT2011
- Author(s)
  Morita T, Yoshida K, Wakasa K, Iizuka M, Ogawa T, Mori M, Sekiya Y, Momen S, Motoyama H, Ikeda K, Yoshizato K, Kawada N.
- Journal Title
  
  Am J Pathol
  
  Volume: 179 Pages: 1050-60
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] Suppression of hepatic stellate cell activation by microRNA-29b2011
- Author(s)
  Sekiya Y, Ogawa T, Yoshizato K他2名
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 412(1) Pages: 74-79
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790666
[Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011
- Author(s)
  Sekiya Y, Ogawa T, Iizuka M, Yoshizato K, Ikeda K, Kawada N.
- Journal Title
  
  J Cell Physiol
  
  Volume: 226 Pages: 2535-42
- Data Source
  KAKENHI-PROJECT-22650224
[Journal Article] Suppression of type I collagen production by microRNA-29b in cultured human stellate cells.2010
- Author(s)
  Ogawa T, Iizuka M, et al.
- Journal Title
  
  Biochem Biophys Res Commun. 391
  
  Pages: 316-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits.2010
- Author(s)
  Ogawa T, Fujii H, et al.
- Journal Title
  
  Am J Pathol.
  
  Volume: 177 Pages: 153-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650224
[Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits2010
- Author(s)
  Ogawa T, Fujii H, Yoshizato K, Kawada N.
- Journal Title
  
  Am J Pathol
  
  Volume: 177 Pages: 153-65
- Data Source
  KAKENHI-PROJECT-22650224
[Journal Article] Down-regulation of cyclin El expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation.2010
- Author(s)
  Sekiya Y, Ogawa T, et al.
- Journal Title
  
  J Cell Physiol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22650224
[Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits.2010
- Author(s)
  Ogawa T, Fujii H, et al.
- Journal Title
  
  Am J Pathol.
  
  Volume: 177 Pages: 153-165
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] Suppression of type I collagen production by microRNA-29b in cultured human stellate cells2010
- Author(s)
  Ogawa T, Iizuka M, Sekiya Y他3名
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 391(1) Pages: 316-321
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790666
[Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation.2010
- Author(s)
  Sekiya Y, Ogawa T, et al.
- Journal Title
  
  J Cell Physiol.
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits2010
- Author(s)
  Ogawa T, Fujii H, Yoshizato K, Kawada N
- Journal Title
  
  Am J Pathol
  
  Volume: 177 Pages: 153-65
- Data Source
  KAKENHI-PROJECT-21390232
[Journal Article] Reversibility of fibrosis, inflammation, and endoplasmic reticulum stress in the liver of rats fed a methionine-choline-deficient diet.2010
- Author(s)
  Mu YP, Ogawa T, Kawada N.
- Journal Title
  
  Lab Invest. 90
  
  Pages: 245-256
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390232
[Patent] 肝線維症の存在及び/又は肝線維症の重症度の判定方法、判定マーカー、判定用キット、肝線維症の治療の効果予測方法、効果予測マーカー、並びに効果予測用キット2010
- Inventor(s)
  河田則文、榎本大、小川智弘
- Industrial Property Rights Holder
  公立大学法人大阪市立大学
- Industrial Property Number
  2010-281254
- Filing Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22650224
[Patent] 肝線維症の存在及び/又は肝線維症の重症度の判定方法、判定マーカー、判定用キット、肝線維症の治療の効果予測方法、効果予測マーカー、並びに効果予測用キット2010
- Inventor(s)
  河田則文、榎本大、小川智弘
- Industrial Property Rights Holder
  公立大学法人大阪市立大学
- Industrial Property Number
  2010-281254
- Filing Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-21390232
[Patent] 肝線維症の存在及び/又は肝線維症の重症度の判定方法、判定マーカー、判定用キット、肝線維症の治療の効果予測方法、効果予測マーカー、並びに効果予測用キット2010
- Inventor(s)
  河田則文、榎本大、小川智弘
- Industrial Property Rights Holder
  大阪市立大学
- Industrial Property Number
  2010-281254
- Filing Date
  2010-12-17
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] Propolis components suppresses activated hepatic stellate cell invasion by inhibition of MMP-2 and MMP-9 expression and its activation2015
- Author(s)
  小川智弘
- Organizer
  第18回国際類洞壁細胞シンポジウム
- Place of Presentation
  アメリカ（パシフィックグローブ）
- Year and Date
  2015-11-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26860140
[Presentation] マイクロRNAの肝線維化診断マーカーとしての有用性とその機能2012
- Author(s)
  小川智弘
- Organizer
  Kansai Liver Club 2012
- Place of Presentation
  太閤園(大阪)
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] マイクロRNAの肝線維化診断マーカーとしての有用性とその機能2012
- Author(s)
  小川智弘、榎本大、藤井英樹, 他3名
- Organizer
  Kansai Liver Club2012
- Place of Presentation
  太閤園(大阪)
- Year and Date
  2012-03-03
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] 慢性肝疾患における肝線維化バイオマーカーとしてのマイクロRNAの有用性2011
- Author(s)
  榎本大、小川智弘、河田則文
- Organizer
  第39回日本肝臓学会西部会
- Place of Presentation
  岡山コンベンションセンター(岡山)
- Year and Date
  2011-12-09
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] 肝線維化と星細胞活性化に関与するマイクロRNAの解析2011
- Author(s)
  飯塚昌司、小川智弘、関谷由美子, 他4名
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  マリンメッセ福岡(福岡)
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] 肝線維化と星細胞活性化に関与するマイクロRNAの解析2011
- Author(s)
  飯塚昌司、榎本大、吉里勝利、小川智弘, 他2名
- Organizer
  第18回肝細胞研究会
- Place of Presentation
  東京ガーデンパレス(東京)
- Year and Date
  2011-06-24
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] C型慢性肝炎患者における肝線維化診断マーカーとしてのマイクロRNAの有用性2011
- Author(s)
  小川智弘
- Organizer
  第97回日本消化器病学会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] 慢性肝疾患における肝線維化バイオマーカーとしてのマイクロRNAの有用性2011
- Author(s)
  飯塚昌司、小川智弘、榎本大, 他3名
- Organizer
  第23回肝類洞壁細胞研究会学術集会
- Place of Presentation
  東京ガーデンパレス(東京)
- Year and Date
  2011-12-17
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] miR-195の肝星細胞増殖における役割についての検討2011
- Author(s)
  関谷由美子、小川智弘、飯塚昌司, 他3名
- Organizer
  第47回日本肝臓学会総会
- Place of Presentation
  ホテルグランパシフィックLE DAIBA(東京)
- Year and Date
  2011-06-03
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] Indication of the Activation of Stellate Cells and the Progression of Liver Fibrosis by MicroRNA-2222011
- Author(s)
  榎本大、小川智弘、飯塚昌司, 他5名
- Organizer
  62nd Annual Meeting of the American Association for the Study of Liver Diseases
- Place of Presentation
  Center(アメリカ)
- Year and Date
  2011-11-06
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] 慢性肝疾患における肝線維化バイオマーカーとしてのmiR-222の有用性2011
- Author(s)
  飯塚昌司、榎本大、小川智弘, 他6名
- Organizer
  第15回日本肝臓学会大会
- Place of Presentation
  マリンメッセ福岡(福岡)
- Year and Date
  2011-10-20
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] C型慢性肝炎患者における肝線維化診断マーカーとしてのマイクロRNAの有用性2011
- Author(s)
  小川智弘、榎本大、河田則文
- Organizer
  第97回日本消化器病学会総会
- Place of Presentation
  京王プラザホテル(東京)
- Year and Date
  2011-05-13
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] Type I interferon inhibits hepatic stellate cell proliferation via downregulation of cyclin E1 by microRNA-1952010
- Author(s)
  関谷由美子、小川智弘、飯塚昌司, 他3名
- Organizer
  15th International Symposium on Cells of the Hepatic Sinusoid
- Place of Presentation
  Hilton Hotel Pasadena(アメリカ)
- Year and Date
  2010-08-31
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] 星細胞活性化に関与するマイクロRNAについての検討2010
- Author(s)
  関谷由美子、小川智弘、飯塚昌司, 他3名
- Organizer
  第6回広島肝臓プロジェクト研究センターシンポジウム
- Place of Presentation
  ホテルグランヴィア広島(広島)
- Year and Date
  2010-06-04
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] マイクロRNAによる肝星細胞のI型コラーゲン発現制御2010
- Author(s)
  飯塚昌司、小川智弘、関谷由美子, 他3名
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形国際ホテル(山形)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] MICRORNA-29B SUPPRESSES TYPE I COLLAGEN AND SP1 EXPRESSION IN INTERFERON-TREATED STELLATE CELLS2010
- Author(s)
  小川智弘、飯塚昌司、関谷由美子, 他3名
- Organizer
  45th annual meeting of the European Association for the Study of the Liver
- Place of Presentation
  ウィーン(オーストリア)
- Year and Date
  2010-04-17
- Data Source
  KAKENHI-PROJECT-22790666
[Presentation] I型インターフェロンのマイクロRNA発現調節を介した肝星細胞増殖抑制作用2010
- Author(s)
  関谷由美子、小川智弘、飯塚昌司, 他3名
- Organizer
  第46回日本肝臓学会総会
- Place of Presentation
  山形国際ホテル(山形)
- Year and Date
  2010-05-27
- Data Source
  KAKENHI-PROJECT-22790666

1. KAWADA Norifumi (30271191)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
2. MORITA Takashi (70150349)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. TAMORI Akihiro (30291595)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. ENOMOTO Masaru (20423874)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. LE Thuy (10572175)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. MOTOYAMA Hiroyuki (00573601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 志賀亮子 (50382221)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ogawa Tomohiro 小川 智弘

OGAWA Tomohiro 小川 智弘

Research Projects

Research Products

Co-Researchers

Study on the molecular mechanisms of fibrogenesis by myofibroblasts which accumulate around fibersPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Involvement of cytoglobin-expressing mesenchymal cells in cancer development

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of liver fibrosis therapy targeting hepatic stellate cells by microRNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analyses of the development of liver cancer and cirrhosis by using cytoglobin-deficient mice

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis.2012

Author(s)

Journal Title

Data Source

[Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis2012

Author(s)

Journal Title

Data Source

[Journal Article] MicroRNA-221/222 upregulation indicates the activation of stellate cells and the progression of liver fibrosis2012

Author(s)

Journal Title

DOI

Data Source

[Journal Article] microRNA-221/222 up-regulation indicates the activation of stellate cells and the progression of liver fibrosis2012

Author(s)

Journal Title

Data Source

[Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011

Author(s)

Journal Title

Data Source

[Journal Article] Down-regulation of cyclin E1 expression by microrna-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011

Author(s)

Journal Title

Data Source

[Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Thuy le TT2011

Author(s)

Journal Title

Data Source

[Journal Article] Promotion of liver and lung tumorigenesis in DEN-treated cytoglobin-deficient mice. Thuy le TT2011

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of hepatic stellate cell activation by microRNA-29b2011

Author(s)

Journal Title

Data Source

[Journal Article] Down-regulation of cyclin E1 expression by microRNA-195 accounts for interferon-β-induced inhibition of hepatic stellate cell proliferation2011

Author(s)

Journal Title

Data Source

[Journal Article] Suppression of type I collagen production by microRNA-29b in cultured human stellate cells.2010

Author(s)

Journal Title

Data Source

[Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits.2010

Author(s)

Journal Title

Data Source

[Journal Article] A human-type nonalcoholic steatohepatitis model with advanced fibrosis in rabbits2010

Author(s)

Ogawa Tomohiro 小川智弘

OGAWA Tomohiro 小川智弘