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Sakurai Katsuyasu  櫻井 勝康

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Researcher Number 70507920
Other IDs
Affiliation (Current) 2025: 筑波大学, 国際統合睡眠医科学研究機構, 准教授
Affiliation (based on the past Project Information) *help 2022 – 2023: 筑波大学, 国際統合睡眠医科学研究機構, 准教授
2018 – 2022: 筑波大学, 国際統合睡眠医科学研究機構, 助教
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (II) / Complex systems / Basic Section 46030:Function of nervous system-related
Except Principal Investigator
Transformative Research Areas, Section (II) / Medium-sized Section 10:Psychology and related fields / Basic Section 59040:Nutrition science and health science-related / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
Keywords
Principal Investigator
神経回路 / 体温 / 恐怖 / 中枢神経薬 / Fos / 生理作用 / オピオイド / 神経活動依存的標識法 / cFos / オーガズム … More / 痛み / ドーパミン / 性行動 / 心拍数 / Trpa1 / 視床下核 / TRPA1 / 恐怖刺激 / 温度 / 体温調節 … More
Except Principal Investigator
神経回路 / 睡眠 / 作動薬 / 神経科学 / 構造生物学 / オピオイド / GPCR / 創薬化学 / クライオ電子顕微鏡単粒子解析 / シグナル伝達 / Gタンパク質共役型受容体 / オピオイド受容体 / 運動制御 / 目標志向的行動 / オペラント条件づけ / 古典的条件づけ / カルシウムイメージング / 予測 / 報酬 / 時間認識 / ケモジェネティクス / リッキング / 運動 / 条件づけ / 時間知覚 / マウス / オプトジェネティクス / 時間 / 認知 / 社会 / 記憶 / 学習 / 行動 / オレキシン受容体作動薬 / オレキシン / 睡眠欲 / cFos / 心的外傷後ストレス障害 / ストレス / 麻酔 / 血糖値 / 眠気 / 神経細胞 Less
  • Research Projects

    (8 results)
  • Research Products

    (16 results)
  • Co-Researchers

    (10 People)
  •  Decomposition of the neuronal mechanisms of opioid receptor ligands-induced physiological responsesPrincipal Investigator

    • Principal Investigator
      Sakurai Katsuyasu
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      University of Tsukuba
  •  Multi-scale platform for untangling physiological complexity

    • Principal Investigator
      Saitoh Tsuyoshi
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      University of Tsukuba
  •  Understanding integrated sensing system of sleep pressure

    • Principal Investigator
      Liu Qonghua
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      University of Tsukuba
  •  オーガズムを捕える -性行動による報酬系賦活化のメカニズムの理解-Principal Investigator

    • Principal Investigator
      櫻井 勝康
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      University of Tsukuba
  •  Elucidation of metabolic rhythm regulation by orexin agonist

    • Principal Investigator
      Fukusumi Shoji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      University of Tsukuba
  •  Structure of behavior: comparative cognitive neurobiological approach

    • Principal Investigator
      Toda Koji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
    • Review Section
      Medium-sized Section 10:Psychology and related fields
    • Research Institution
      Keio University
      Waseda University
  •  三叉神経のTRPA1を介した急激な体温低下を生みだす脳内メカニズムの解明Principal Investigator

    • Principal Investigator
      櫻井 勝康
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      University of Tsukuba
  •  Identification of neural pathway involving innate fear-induced hypothermia and bradycardiaPrincipal Investigator

    • Principal Investigator
      Sakurai Katsuyasu
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 46030:Function of nervous system-related
    • Research Institution
      University of Tsukuba

All 2023 2022 2021 2020 2019

All Journal Article Presentation

  • [Journal Article] The present and future of synthetic orexin receptor agonists2023

    • Author(s)
      Saitoh Tsuyoshi、Sakurai Takeshi
    • Journal Title

      Peptides

      Volume: 167 Pages: 171051-171051

    • DOI

      10.1016/j.peptides.2023.171051

    • Peer Reviewed
    • Data Source
      KAKENHI-ORGANIZER-21H05111
  • [Journal Article] Discovery of novel orexin receptor antagonists using a 1,3,5-trioxazatriquinane bearing multiple effective residues (TriMER) librasy2022

    • Author(s)
      Saitoh T, Amezawa M, Horiuchi J, Nagumo Y, Yamamoto N, Kutsumura N, Ohshita R, Tokuda A, Irukayama-Tomobe Y, Ogawa Y, Ishikawa Y, Hasegawa E, Sakurai T, Uchida Y, Sato T, Gouda H, Tanimura R, Yanagisawa M, Nagase H.
    • Journal Title

      Eur J Med Chem

      Volume: 240 Pages: 114505-27

    • DOI

      10.1016/j.ejmech.2022.114505

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K07314, KAKENHI-PROJECT-22H04918, KAKENHI-ORGANIZER-21H05111, KAKENHI-PROJECT-20H03361
  • [Journal Article] Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice2021

    • Author(s)
      Can Liu, Chia-Ying Lee, Greg Asher, Liqin Cao, Yuka Terakoshi, Peng Cao, Reiko Kobayakawa, Ko Kobayakawa, Katsuyasu Sakurai, Qinghua Liu
    • Journal Title

      Nature Communications

      Volume: 12 Issue: 1 Pages: 2648-2648

    • DOI

      10.1038/s41467-021-22914-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06738, KAKENHI-PUBLICLY-19H05006, KAKENHI-PROJECT-18K06515, KAKENHI-PROJECT-17H06095, KAKENHI-PROJECT-20K20578, KAKENHI-PUBLICLY-20H04849
  • [Journal Article] Posterior subthalamic nucleus (PSTh) mediates innate fear-associated hypothermia in mice.2021

    • Author(s)
      Liu C, Lee CY, Asher G, Cao L, Terakoshi Y, Cao P, Kobayakawa R, Kobayakawa K, Sakurai K, Liu Q
    • Journal Title

      Nature Communications

      Volume: -

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0070
  • [Journal Article] Hyper-Activation of mPFC Underlies Specific Traumatic Stress-Induced Sleep-Wake EEG Disturbances2020

    • Author(s)
      Tingting Lou, Jing Ma, Zhiqiang Wang, Yuka Terakoshi, Chia-Ying Lee, Greg Asher, Liqin Cao, Zhiyu Chen, Katsuyasu Sakurai, Qinghua Liu
    • Journal Title

      Frontiers in Neuroscience

      Volume: 14 Pages: 883-883

    • DOI

      10.3389/fnins.2020.00883

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06738, KAKENHI-PROJECT-19H03263, KAKENHI-PROJECT-18KK0070
  • [Journal Article] A discrete neuronal circuit induces a hibernation-like state in rodents2020

    • Author(s)
      Takahashi TM, Sunagawa GA, Soya S, Abe M, Sakurai K, Ishikawa K, Yanagisawa M, Hama H, Hasegawa E, Miyawaki A, Sakimura K, Takahashi M, Sakurai T.
    • Journal Title

      Nature

      Volume: - Issue: 7814 Pages: 109-114

    • DOI

      10.1038/s41586-020-2163-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0070, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-19K09241, KAKENHI-PROJECT-18KK0458, KAKENHI-ORGANIZER-16H06400, KAKENHI-PLANNED-16H06401, KAKENHI-PUBLICLY-19H04894, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02595, KAKENHI-PROJECT-19J20876, KAKENHI-PROJECT-19K22465
  • [Journal Article] General anesthetics activate a potent central pain-suppression circuit in the amygdala.2020

    • Author(s)
      Hua T, Chen B, Lu D, Sakurai K, Zhao S, Han BX, Kim J, Yin L, Chen Y, Lu J, Wang F.
    • Journal Title

      Nature Neuroscience

      Volume: - Issue: 7 Pages: 854-868

    • DOI

      10.1038/s41593-020-0632-8

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0070
  • [Journal Article] A specialized neural circuit gates social vocalizations in the mouse.2019

    • Author(s)
      Tschida K, Michael V, Takatoh J, Han BX, Zhao S, Sakurai K, Mooney R, Wang F.
    • Journal Title

      Neuron

      Volume: 103 Issue: 3 Pages: 459-472

    • DOI

      10.1016/j.neuron.2019.05.025

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0070
  • [Presentation] ON-OFFを見る -神経活動の遷移の大規模な可視化-2023

    • Author(s)
      櫻井勝康
    • Organizer
      日本薬学会第143年会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21H05111
  • [Presentation] 新規機能的コネクトーム解析法2022

    • Author(s)
      櫻井勝康
    • Organizer
      第95回日本生化学会大会
    • Invited
    • Data Source
      KAKENHI-ORGANIZER-21H05111
  • [Presentation] Discovery of novel orexin receptor antagonists with 1,3,5-trioxazatriquinane skeleton2021

    • Author(s)
      Mao Amezawa; Tsuyoshi Saitoh; Yukiko Ishikawa; Yoko Irukayama; Emi Hasegawa; Hiroaki Gouda; Naoshi Yamamoto; Noriki Kutsumura; Yasuyuki Nagumo; Sakurai Takeshi; Masashi Yanagisawa; Hiroshi Nagase
    • Organizer
      The 2021 International Chemical Congress of Pacific Basin Societies (Pacifichem)
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-21H05111
  • [Presentation] Design and Synthesis of Novel Orexin Receptor Antagonists with 1,3,5-Trioxazatriquinane skeleton2021

    • Author(s)
      Mao Amezawa; Jumpei Horiuchi; Tsuyoshi Saitoh; Ryuichiro Ohshita; Naoshi Yamamoto; Yasuyuki Nagumo; Yukiko Ishikawa; Yoko Irukayama; Emi Hasegawa; Noriki Kutsumura; Ryuji Tanimura; Sakurai Takeshi; Masashi Yanagisawa; Hiroshi Nagase
    • Organizer
      AIMECS2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-ORGANIZER-21H05111
  • [Presentation] Effects of optogenetic manipulations of GABAergic neurons in the hippocampus on interval timing in head-fixed mice.2020

    • Author(s)
      Yatagai, S., Ujihara, Y., Niki, Y., Yamada, K., Sakurai, K. & Toda, K.
    • Organizer
      日本動物心理学会第80回大会
    • Data Source
      KAKENHI-PROJECT-18KK0070
  • [Presentation] Neural mechanism of time perception.2020

    • Author(s)
      Toda, K., Yatagai, S., Yamada, K., Yamamoto, K., Sakurai, K., Meck, WH. & Yin, HH.
    • Organizer
      日本生理学会第97回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KK0070
  • [Presentation] Neural correlates of time perception in head-fixed mice.2019

    • Author(s)
      Yatagai, S., Yamada, K., Yamamoto, K., Sakurai, K. & Toda, K.
    • Organizer
      日本動物心理学会第79回大会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18KK0070
  • [Presentation] Discovery of Novel Orexin Receptor Antagonist with 1,3,5-Trioxazatriquinane Skeleton2019

    • Author(s)
      3.Amezawa M, Horiuchi J, Saitoh T, Ogawa Y, Ishikawa Y, Irukayama Y, Hasegawa E, Hayakawa D, Watanabe Y, Nagumo Y, Yamamoto N, Kutsumura N, Gouda H, Sakurai T, Yanagisawa M, Nagase H.
    • Organizer
      The 27th French-Japanese Symposium on Medicinal and Fine Chemistry Hotel Leopalace Hakata
    • Data Source
      KAKENHI-PROJECT-18K11014
  • 1.  Saitoh Tsuyoshi (80609933)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 2.  Liu Qonghua (90723792)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  Fukusumi Shoji (10750002)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  Toda Koji (60794948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 5.  入鹿山 容子 (90312834)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 6.  橘 吉寿 (50373197)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  井上 飛鳥 (50525813)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  寿野 良二 (60447521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  SOU Reikin
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 10.  桜井 武
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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