Yamashita Akiko 山下明子

… Alternative Names

YAMASHITA Akiko 山下明子

Less

Researcher Number	70511319
Other IDs
Affiliation (Current)	2025: 九州大学, 歯学研究院, 助教
Affiliation (based on the past Project Information) *help	2015 – 2024: 九州大学, 歯学研究院, 助教 2014 – 2016: 九州大学, 大学病院, 助教 2013: 広島大学, その他の研究科, 助教 2013: 広島大学, 医歯薬保健学研究科, 助教 2013: 広島大学, 大学院医歯薬保健学研院, 助教 … More 2012 – 2013: 広島大学, 医歯薬保健学研究院, 助教 2012: 広島大学, 医歯薬保健学研究院(歯), 助教 2011: 広島大学, 医歯(薬)学総合研究科, 助教 2011: 広島大学, 医歯薬学総合研究科, 助教 2008 – 2011: Hiroshima University, 大学院・医歯薬学総合研究科, 助教 2009: Hiroshima University, 医歯薬学総合研究科, 助教 Less
Review Section/Research Field	Principal Investigator Basic Section 57030:Conservative dentistry-related / Periodontal dentistry / Periodontology Except Principal Investigator Periodontology / Conservative dentistry / Periodontal dentistry
Keywords	Principal Investigator 歯周病 / 歯肉増殖症 / メタボリックシンドローム / SPOCK1 / アディポサイトカイン / 肥満 / プロテオグリカン / 歯肉増殖 / カテプシン / フラボノイド / マクロファージ / 脂肪細胞 / 抗炎症作用 … More Except Principal Investigator … More インスリン抵抗性 / 脂肪細胞 / 脂肪組織 / 歯周病 / 樹状細胞 / 歯周炎症 / 肥満 / 軽微な慢性炎症 / 歯周医学 / 炎症性サイトカイン / 共培養 / 炎症 / マクロファージ / マイクロアレイ / 補体調節因子 / β酸化 / 脂肪分化 / 脂肪蓄積 / CfB / 脂肪細胞分化 / インスリン感受性 / 遺伝子導入マウス / 遺伝子改変マウス / ccr7 / ccl19 / 褐色脂肪細胞 / 白色脂肪細胞 / 熱産生 / 脂肪細胞―マクロファージ相互作用 / エネルギー代謝 / eGFR / lipocalin-2 / 心腎連関 / メサンギウム / CKD / 膵ベータ細胞 / 膵アルファ細胞 / 脂肪組織炎症 / 膵β細胞 / 膵α細胞 / 内毒素 / 細胞死 / 膵島炎症 / 脂肪炎症 / ケモカイン / 脂肪細胞－マクロファージ相互作用 / 急性炎症 / 液性因子 / マイクロアレイ解析 / プロテオミクス / バイオアッセイ / DNAマイクロアレイ / 腫瘍壊死因子 / 歯髄 / 炎症メディエーター / 分泌蛋白 / 融解壊死 / 歯髄炎症 / TNF-alpha / 歯髄細胞 / 遺伝子発現 / 炎症制御 / サイトカイン / 炎症反応 / 歯髄炎 / カテプシン-L / ライソゾーム酵素 / 歯肉増殖症 / ヒト歯肉繊維芽細胞 / カテプシン / ヒト歯肉線維芽細胞 / 多毛症 / カテプシンL Less

miRNAを標的とした薬剤性歯肉増殖症新規治療薬の開発Principal Investigator
- Principal Investigator
  
  山下明子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kyushu University
歯肉増殖症や肥満に関わる新規分子SPOCK1のシグナリング経路の探索Principal Investigator
- Principal Investigator
  
  山下明子
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kyushu University
The elucidation of the pathophysiology of gingival overgrowth.Principal Investigator
- Principal Investigator
  
  Yamashita Akiko
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 57030:Conservative dentistry-related
- Research Institution
  Kyushu University
New direction in periodontal medicine: Association of periodontal inflammation with energy metabolism
- Principal Investigator
  
  Nishimura Fusanori
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Kyushu University
Role of complement factor B on insulin resistance-related disease
- Principal Investigator
  
  Iwashita Misaki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Kyushu University
the unravelling of the role of cathepsin in gingival overgrowthPrincipal Investigator
- Principal Investigator
  
  Yamashita Akiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontology
- Research Institution
  Kyushu University
Molecular basis for periodontal medicine based on the interaction between infiltrated inflammatory cells and resident cells.
- Principal Investigator
  
  NISHIMURA FUSANORI
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Periodontology
- Research Institution
  Kyushu University
Basic study aimed at the control of insulin resistance induced periodontal inflammation that target miRNAPrincipal Investigator
- Principal Investigator
  
  YAMASHITA Akiko
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
Analysis of patients with gingival hyperplasia and hypertrichosis
- Principal Investigator
  
  ARAKAWA Makoto
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
Comprehensive analysis of the molecules up- or down- regulataed in dental pulp cells co-cultured with macrophages
- Principal Investigator
  
  NISHIMURA Fusanori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Conservative dentistry
- Research Institution
  Kyushu University
  Hiroshima University
Global analysis of adipocytes co-cultured with macrophages treated with anti-inflammatory substancePrincipal Investigator
- Principal Investigator
  
  YAMASHITA Akiko
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University
The basic and clinical study of the relevance of periodontal disease and metabolic syndrome.Principal Investigator
- Principal Investigator
  
  YAMASHITA Akiko
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (Start-up)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Hiroshima University

[Book] 4. 高齢者・有病者の歯内治療糖尿病とエンド―ぺリオ, 興地隆史、井澤常泰、石井信之、木ノ本喜史編集「DENTAL DIAMOND 増刊号ライフステージと歯内療法歯の長期保存のために」2013
- Author(s)
  山下明子、西村英紀
- Publisher
  デンタルダイアモンド社(共同執筆)
- Data Source
  KAKENHI-PROJECT-23659889
[Journal Article] Endothelial Insulin Resistance Exacerbates Experimental Periodontitis2023
- Author(s)
  Zeze T.、Shinjo T.、Sato K.、Nishimura Y.、Imagawa M.、Chen S.、Ahmed A.-k.、Iwashita M.、Yamashita A.、Fukuda T.、Sanui T.、Park K.、King G.L.、Nishimura F.
- Journal Title
  
  Journal of Dental Research
  
  Volume: 102 Issue: 10 Pages: 1152-1161
- DOI
  10.1177/00220345231181539
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0212, KAKENHI-PROJECT-21K09897, KAKENHI-PROJECT-20K09958, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-23K27774
[Journal Article] Epithelial-to-mesenchymal transition, inflammation, subsequent collagen production, and reduced proteinase expression cooperatively contribute to cyclosporin-A-induced gingival overgrowth development2023
- Author(s)
  Imagawa Mio、Shinjo Takanori、Sato Kohei、Kawakami Kentaro、Zeze Tatsuro、Nishimura Yuki、Toyoda Masaaki、Chen Shuang、Ryo Naoaki、Ahmed Al-kafee、Iwashita Misaki、Yamashita Akiko、Fukuda Takao、Sanui Terukazu、Nishimura Fusanori
- Journal Title
  
  Frontiers in Physiology
  
  Volume: 14 Pages: 01-16
- DOI
  10.3389/fphys.2023.1298813
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0212, KAKENHI-PROJECT-21K09897, KAKENHI-PROJECT-23K09170, KAKENHI-PROJECT-20K09958, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-20H03865, KAKENHI-PROJECT-23K27774
[Journal Article] miR-582-5p targets Skp1 and regulates NF-κB signaling-mediated inflammation2023
- Author(s)
  Li Rongzhi、Sano Tomomi、Mizokami Akiko、Fukuda Takao、Shinjo Takanori、Iwashita Misaki、Yamashita Akiko、Sanui Terukazu、Nakatsu Yusuke、Sotomaru Yusuke、Asano Tomoichiro、Kanematsu Takashi、Nishimura Fusanori
- Journal Title
  
  Archives of Biochemistry and Biophysics
  
  Volume: 734 Pages: 109501-109501
- DOI
  10.1016/j.abb.2022.109501
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09897, KAKENHI-PROJECT-22K09904, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-20H03865, KAKENHI-PROJECT-21K19380, KAKENHI-PROJECT-20KK0212, KAKENHI-PROJECT-23K09170, KAKENHI-PROJECT-21K09817, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-23K27650
[Journal Article] XAF1 overexpression exacerbates diabetes by promoting pancreatic β-cell apoptosis.2022
- Author(s)
  Nishimura Y, Iwashita M, Hayashi M, Shinjo T, Watanabe Y, Zeze T, Yamashita A, Fukuda T, Sanui T, Sano T, Asano T, Nishimura F.
- Journal Title
  
  Acta Diabetol
  
  Volume: 59 Issue: 10 Pages: 1275-1286
- DOI
  10.1007/s00592-022-01930-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09958, KAKENHI-PROJECT-21K09897, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-21K19380
[Journal Article] A Case Report of Improved Palmoplantar Pustulosis following Periodontal Treatment and Possible Association with Diminished Systemic Subclinical Inflammation2021
- Author(s)
  Yamashita Akiko、Sano Tomomi、Iwashita Misaki、Nishimura Fusanori
- Journal Title
  
  Case Reports in Dermatological Medicine
  
  Volume: 2021 Pages: 1-5
- DOI
  10.1155/2021/5548760
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09578, KAKENHI-PROJECT-20K18512
[Journal Article] The Link Between Periodontal Inflammation and Obesity2021
- Author(s)
  Iwashita Misaki、Hayashi Masato、Nishimura Yuki、Yamashita Akiko
- Journal Title
  
  Current Oral Health Reports
  
  Volume: 8 Issue: 4 Pages: 76-83
- DOI
  10.1007/s40496-021-00296-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09578, KAKENHI-PROJECT-21K21043
[Journal Article] Adipose-specific C-C motif chemokine ligand (CCL) 19 overexpression drives the mice to both insulin resistance and weight gain2021
- Author(s)
  Hayashi Masato、Iwashita Misaki、Nishimura Yuki、Shinjo Takanori、Sano Tomomi、Yamashita Akiko、Fukuda Takao、Sanui Terukazu、Asano Tomoichiro、Nishimura Fusanori
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 9 Issue: 1 Pages: e001871-e001871
- DOI
  10.1136/bmjdrc-2020-001871
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09578, KAKENHI-PROJECT-20H03732, KAKENHI-PROJECT-20K09958, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-21K21089, KAKENHI-PROJECT-20KK0212
[Journal Article] SPOCK1 is a novel inducer of epithelial to mesenchymal transition in drug-induced gingival overgrowth2020
- Author(s)
  Alshargabi Rehab、Sano Tomomi、Yamashita Akiko、Takano Aiko、Sanada Taiki、Iwashita Misaki、Shinjo Takanori、Fukuda Takao、Sanui Terukazu、Kishida Shosei、Nishimura Fusanori
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 9785-9785
- DOI
  10.1038/s41598-020-66660-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09578, KAKENHI-PROJECT-20K09958, KAKENHI-PROJECT-19K22721, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-18K17071
[Journal Article] SPOCK1 induces adipose tissue maturation: New insights into the function of SPOCK1 in metabolism2020
- Author(s)
  Alshargabi Rehab、Shinjo Takanori、Iwashita Misaki、Yamashita Akiko、Sano Tomomi、Nishimura Yuki、Hayashi Masato、Zeze Tatsuro、Fukuda Takao、Sanui Terukazu、Nishimura Fusanori
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 533 Issue: 4 Pages: 1076-1082
- DOI
  10.1016/j.bbrc.2020.09.129
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09578, KAKENHI-PROJECT-20K09958, KAKENHI-PROJECT-19K22721, KAKENHI-PROJECT-20K18512, KAKENHI-PROJECT-20K18513, KAKENHI-PROJECT-18K17071
[Journal Article] Ccr7 null mice are protected against diet-induced obesity via Ucp1 upregulation and enhanced energy expenditure2019
- Author(s)
  Sano Tomomi、Sanada Taiki、Sotomaru Yusuke、Shinjo Takanori、Iwashita Misaki、Yamashita Akiko、Fukuda Takao、Sanui Terukazu、Asano Tomoichiro、Kanematsu Takashi、Nishimura Fusanori
- Journal Title
  
  Nutrition & Metabolism
  
  Volume: 16 Issue: 1 Pages: 43-43
- DOI
  10.1186/s12986-019-0372-5
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-17K11644, KAKENHI-PROJECT-17K11986
[Journal Article] Dental pulp cell-derived powerful inducer of TNF-α comprises PKR containing stress granule rich microvesicles.2019
- Author(s)
  Suzuki S, Fukuda T, Nagayasu S, Nakanishi J, Yoshida K, Hirata-Tsuchiya S, Nakao Y, Sano T, Yamashita A, Yamada S, Ohta K, Shiba H, Nishimura F.
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 3825-3825
- DOI
  10.1038/s41598-019-40046-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K11987, KAKENHI-PROJECT-18K17071, KAKENHI-PROJECT-16H05555, KAKENHI-PROJECT-17K11706, KAKENHI-PROJECT-16K11551
[Journal Article] Adipose tissue complement factor B promotes adipocyte maturation2018
- Author(s)
  Matsunaga H, Iwashita M, Shinjo T, Yamashita A, Tsuruta M, Nagasaka S, Taniguchi A, Fukushima M, Watanabe N, Nishimura F
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 495 Issue: 1 Pages: 740-748
- DOI
  10.1016/j.bbrc.2017.11.069
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11835, KAKENHI-PROJECT-16H05555
[Journal Article] Metabolic Endotoxemia-Activated Macrophages Promote Pancreatic β Cell Death via IFNβ-Xaf1 Pathway2017
- Author(s)
  Tsuruta Mitsudai、Iwashita Misaki、Shinjo Takanori、Matsunaga Hiroaki、Yamashita Akiko、Nishimura Fusanori
- Journal Title
  
  Hormone and Metabolic Research
  
  Volume: 50 Issue: 02 Pages: 160-167
- DOI
  10.1055/s-0043-121467
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H05555
[Journal Article] Protection from diet-induced obesity and insulin resistance in mice lacking CCL19-CCR7 signaling.2015
- Author(s)
  Sano T, Iwashita M, Nagayasu S, Yamashita A, Shinjo T, Hashikata A, Asano T, Kushiyama A, Ishimaru N, Takahama Y, Nishimura F
- Journal Title
  
  Obesity
  
  Volume: 23 Issue: 7 Pages: 1460-1471
- DOI
  10.1002/oby.21127
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K15676, KAKENHI-ORGANIZER-24111001, KAKENHI-PLANNED-24111004, KAKENHI-PROJECT-25461372, KAKENHI-PROJECT-26861816, KAKENHI-PROJECT-25293425
[Journal Article] he Inflammation-lipocalin2 axis may contribute to the development of chronic kidney disease.2014
- Author(s)
  Hashikata A, Yamashita A, Suzuki S, Nagayasu S, Shinjo T, Taniguchi A, Fukushima M, Nakai Y, Nin K, Watanabe N, Asano T, Abiko Y, Kushiyama A, Nagasaka S, Nishimura F.
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: ２９ Issue: 3 Pages: 611-618
- DOI
  10.1093/ndt/gft449
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293425, KAKENHI-PROJECT-25461372
[Journal Article] Flavonol-containing phosphorylated pullulan may attenuate pulp inflammation2013
- Author(s)
  J. Yonehiro
- Journal Title
  
  Int. Endod. J.
  
  Volume: 46 Issue: 2 Pages: 119-127
- DOI
  10.1111/j.1365-2591.2012.02095.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220009, KAKENHI-PROJECT-22249066, KAKENHI-PROJECT-23659889, KAKENHI-PROJECT-24659873, KAKENHI-PROJECT-24659893
[Journal Article] Establishment of ex vivo pulpitis model by co-culturing immortalized dental pulp cells and macrophages2012
- Author(s)
  J. Yonehiro
- Journal Title
  
  Int. Endod. J.
  
  Volume: 45 Issue: 12 Pages: 1103-1108
- DOI
  10.1111/j.1365-2591.2012.02074.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22220009, KAKENHI-PROJECT-22249066, KAKENHI-PROJECT-23659889, KAKENHI-PROJECT-24659873, KAKENHI-PROJECT-24659893
[Journal Article] Adipocyte-macrophage interaction may mediate LPS-induced low-grade inflammation : potentiallink with metabolic complicationsInnate Immunity2012
- Author(s)
  Nakarai H., Yamashita A., Nagayasu S., Iwashita M., Kumamoto S., Ohyama H., Hata M., Soga Y., Kushiyama A., Asano T., Abiko Y., Nishimura F
- Volume
  18(1)
- Pages
  164-170
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792086
[Journal Article] Adipocyte-macrophage interaction may mediate LPS-induced low-grade inflammation : potential link with metabolic complications2011
- Author(s)
  Hideo Nakarai, Akiko Yamashita, et.al.
- Journal Title
  
  Innate Immunity
  
  Volume: (掲載決定)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22792086
[Journal Article] 糖尿病と易感染性歯周病と糖尿病2010
- Author(s)
  山下明子, 西村英紀
- Journal Title
  
  Diabetes frontier
  
  Volume: 21(3) Pages: 302-306
- Data Source
  KAKENHI-PROJECT-22792086
[Journal Article] Periodontal disease : Chronic low-grade inflammation accelerating aging2009
- Author(s)
  Fusanori Nishimura, Yoshihiko Soga, Akiko Yamashita
- Journal Title
  
  Inflammation and Regeneration 29(3)
  
  Pages: 186-189
- NAID
  10024797364
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890143
[Journal Article] 歯周病と糖尿病2009
- Author(s)
  西村英紀, 山下明子
- Journal Title
  
  内分泌・糖尿病科 28(5)
  
  Pages: 366-370
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890143
[Journal Article] Chronic low-grade inflammation accelerating aging2009
- Author(s)
  Fusanori Nishimura, Yoshihiko Soga, Akiko Yamashita, Periodontal disease
- Journal Title
  
  Inflammation and Regeneration 29(3)
  
  Pages: 186-189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890143
[Journal Article] DNA microarray analyses of genes expressed differentially in 3T3-L1 adipocytes co-cultured with murine macrophage cell line RAW264. 7 in the presence of the toll-like receptor 4 ligand bacterial endotoxin2008
- Author(s)
  A Yamashita, Y Soga, Y Iwamoto, T Asano, Y Li, Y Abiko, F Nishimura
- Journal Title
  
  International journal of Obesity 32
  
  Pages: 1725-729
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890143
[Journal Article] DNA microarray analyses of genes expressed differentially in 3T3-L1 adipocytes co-cultured with murine macrophage cell line RAW264.7 in the presence of the toll-like receptor 4 ligand bacterial endotoxin2008
- Author(s)
  Akiko Yamashita
- Journal Title
  
  International journal of Obesity 32
  
  Pages: 1725-1729
- NAID
  120001092430
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 血管内皮細胞におけるインスリン抵抗性は、インスリン作用によるPI3K-Akt－FoxO１経路を介した炎症誘導性VCAM－１発現を破綻させることで歯周炎の増悪に寄与する2023
- Author(s)
  瀬々起朗、新城尊徳、西村優輝、佐藤晃平、今川澪、陳爽、梁尚陽、岩下未咲、山下明子、西村英紀
- Organizer
  第６６回日本歯周病学会春季学術大会（高松市）
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] 掌蹠膿疱症の増悪因子として口腔内の感染病巣が疑われた慢性歯周炎患者の一症例2023
- Author(s)
  山下明子、新城尊徳、西村英紀
- Organizer
  第６６回秋季日本雌雄病学会学術大会（長崎市）
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] 血管内皮細胞におけるインスリン抵抗性は糖尿病関連歯周炎を増悪させる2023
- Author(s)
  瀬々起朗、新城尊徳、西村優輝、佐藤晃平、今川澪、陳爽、梁尚陽、岩下未咲、山下明子、西村英紀
- Organizer
  日本歯科保存学会２０２３年度春季学術大会（第１５３回）（松江市）
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] 実験的歯周炎を惹起したKK-Ayマウスでは、糸球体中HPGDS発現上昇を介して腎症が増悪する2023
- Author(s)
  佐藤晃平、新城尊徳、瀬々起朗、今川澪、梁尚陽、陳爽、西村優輝、岩下未咲、山下明子、西村英紀
- Organizer
  第６６回日本歯周病学会春季学術大会（高松市）
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] 実験的歯周炎によって２型糖尿病モデルKK-Ayマウスにおける腎症は増悪する2023
- Author(s)
  新城尊徳、佐藤晃平、横溝久、瀬々起朗、今川澪、岩下未咲、山下明子、西村英紀
- Organizer
  第６６回日本糖尿病学会年次学術集会（鹿児島市）
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] SPOCK1はシクロスポリンによる薬剤性歯肉増殖症において歯周炎症を介した歯肉肥厚と歯槽骨吸収を増大する2022
- Author(s)
  今川澪、新城尊徳、山下明子、佐藤晃平、瀬々起朗、西村優輝、川上賢太郎、岩下未咲、西村英紀
- Organizer
  第65回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] XAF１の過剰発現は膵β細胞のアポトーシスを促進することで糖尿病を悪化させる2022
- Author(s)
  西村優輝、岩下未咲、新城尊徳、瀬々起朗、佐野朋美、山下明子、西村英紀
- Organizer
  第157回日本歯科保存学会2022年度秋季学術大会
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] 実験的歯周炎により2型糖尿病モデルKK-Aｙマウスの糖尿病性腎臓病は増悪する2022
- Author(s)
  佐藤晃平、新城尊徳、瀬々起朗、今川澪、西村優輝、岩下未咲、山下明子、西村英紀
- Organizer
  令和4年度日本歯周病学会九州五大学日本臨床歯周病学会九州支部合同研修会
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] Endothelial insulin resistance contributes to the pathogenesis of diabetes-related periodontitis.2022
- Author(s)
  Tatsuo Zeze, Takanori Shinjo, Kohei Sato, Mio Imagawa, Yuki Nishimura,Misaki Iwashita,Akiko Yamashita, Takao Fukuda, Terukazu Sanui, Fusanori Nishimura
- Organizer
  2022 IADR/APR General Session
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] SPOCK1はシクロスポリンによる薬剤性歯肉増殖症において歯周炎症を介した歯肉肥厚と歯槽骨吸収を増大する2022
- Author(s)
  今川澪、新城尊徳、山下明子、佐藤晃平、瀬々起朗、西村優輝、川上賢太郎、岩下未咲、西村英紀
- Organizer
  第156回日本歯科保存学会2022年春季学術大会
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] Identification of microRNA regulating NF-κB pathway in macrophage.2021
- Author(s)
  李栄智、佐野朋美、新城尊徳、岩下未咲、山下明子、福田隆男、西村英紀
- Organizer
  第64回春季日本歯周病学会学術大会、
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] High-fat diet-induced XAF1exacerbates diabetes by promoting pancreatic β-cell apoptosis.2021
- Author(s)
  Yuki　Nishimura, Misaki Iwashita, Masato Hayashi, Takanori Shinjo, Tatsuro Zeze, Akiko Yamashita, Takao Fukuda, Terukazu Sanui, Tomomi Sano, Fusanori Nishimura.
- Organizer
  JADR 69th annual meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 実験的歯周炎により2型糖尿病モデルKK-Ayマウスの糖尿病性腎臓病は増悪する2021
- Author(s)
  佐藤晃平、新城尊徳、西村優輝、瀬々起朗、今川澪、岩下未咲、山下明子、西村英紀．
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] dentification of microRNA regulating NF-κB pathway in macrophage.2021
- Author(s)
  Rongzhi Li, Tomimi Sano, Takanori Shinjo, Misaki Iwashita, Akiko Yamashita, Takao Fukuda, Fusanori Nishimura.
- Organizer
  KOB・OBT合同国際シンポジウム
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 血管内皮細胞におけるインスリン抵抗性は炎症誘導性VCAM-1発現制御が破綻することで歯周炎増悪に寄与する2021
- Author(s)
  瀬々起朗、新城尊徳、西村優輝、佐藤晃平、今川澪、岩下未咲、山下明子、西村英紀
- Organizer
  第64回日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 実験的歯周炎により2型糖尿病モデルKK-Ayマウスの糖尿病性腎臓病は増悪する2021
- Author(s)
  佐藤晃平、新城尊徳、西村優輝、瀬々起朗、今川澪、岩下未咲、山下明子、西村英紀
- Organizer
  第64回秋季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] Insulin resistance in vascular endothelial cells contributes to the exacerbation of periodontitis via dysregulation of inflammation-induced VCAM-1expression.2021
- Author(s)
  Zeze T, Shinjo T, Nishimura Y, Sato K, Imagawa M, Yamashita A, Nishimura F
- Organizer
  JADR 69th annual meeting.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] SPOCK1は歯周炎における歯槽骨吸収と歯肉肥厚に関与する2021
- Author(s)
  今川澪、新城尊徳、山下明子、西村優輝、瀬々起朗、佐藤晃平、岩下未咲、西村英紀
- Organizer
  2021年度日本歯科保存学会秋季学術大会（第154回）
- Data Source
  KAKENHI-PROJECT-21K09897
[Presentation] SPOCK1は歯周炎における歯槽骨吸収と歯肉肥厚に関与する2021
- Author(s)
  今川澪、新城尊徳、山下明子、西村優輝、瀬々起朗、佐藤晃平、岩下未咲、西村英紀
- Organizer
  2021年度日本歯科保存学会秋季学術大会（第154回）
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 膵β細胞Xaf１が膵島機能および糖尿病発症に及ぼす影響2021
- Author(s)
  西村優輝、岩下未咲、林大翔、新城尊徳、瀬々起朗、佐野朋美、山下明子、西村英紀
- Organizer
  2021年度日本歯科保存学会春季学術大会（第154回）
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 脂肪細胞CCL19が脂肪組織炎症および脂質代謝に及ぼす影響2020
- Author(s)
  林大翔、岩下未咲、西村優輝、新城尊徳、瀬々起朗、佐野朋美、山下明子、西村英紀
- Organizer
  第63回春季歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 膵β細胞Xaf1が膵島機能および糖尿病発症に及ぼす影響2020
- Author(s)
  西村優輝、岩下未咲、林大翔、新城尊徳、佐野朋美、山下明子、西村英紀
- Organizer
  第152回日本歯科保存学会春季学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 脂肪・歯周組織で発現誘導されるmiRNAによる抗炎症効果の検討2019
- Author(s)
  眞田大樹、佐野朋美、松永紘明、岩下未咲、山下明子、Rehab　Alshargabi、兼松隆、西村英紀
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] 脂肪細胞に発現するCCL19が脂肪組織炎症および代謝制御に及ぼす影響2019
- Author(s)
  林大翔、岩下未咲、西村優輝、佐野朋美、山下明子、西村英紀
- Organizer
  第150回日本歯科保存学会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] SPOCK1 is a novel epithelial mesenchymal transition (EMT) inducer in calsium channtel blocker-induced gingival overgrowth.2019
- Author(s)
  Rehab　Alshargabi, Tomomi Sano, Akiko Yamashita,Taiki Sanada, Takao Fukuda, Misaki Iwashita, Terukazu Sanui, Fusanori Nishimura
- Organizer
  2019　Kyudai Oral Bioscience & OBT Research Center Joint International Symposium
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] SPOCK-1　upregulation is a novel epithelial mesenchymal transition (EMT) inducer in calcium channel blocker-induced gingival overgrowth.2019
- Author(s)
  Rehab　Alshargabi, Tomomi Sano, Akiko Yamashita,Taiki Sanada, Takao Fukuda, Misaki Iwashita, Terukazu Sanui, Fusanori Nishimura
- Organizer
  第62回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] identification of micro RNAs involved in adipose tissue inflammation.2019
- Author(s)
  Sano　T, Sanada T, Rehab A, Sotomaru Y, Iwashita M, Yamashita A, Nishimura F
- Organizer
  13th Asian Pacific Society of Periodontoligy Meeting.
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] the role of proteoglycans in the pathogenesis of drug induces gingival overgrowth (DIGO)2018
- Author(s)
  Rehab　Alshargabi, Aiko Takano, Akiko Yamashita, Misaki Iwashita, Takao Fukuda, Terukazu Sanui, Fusanori Nishimura
- Organizer
  第61回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] The Role of Proteoglycans in Drug Indused Gingival Overgrowth (DIGO)2018
- Author(s)
  Rehab　Alshargabi, Tomomi Sano, Akiko Yamashita,Taiki Sanada, Takao Fukuda, Misaki Iwashita, Terukazu Sanui, Fusanori Nishimura
- Organizer
  第149回秋季日本歯科保存学会学術大会
- Data Source
  KAKENHI-PROJECT-18K09578
[Presentation] Complement factor Bは脂肪細胞の成熟および肥満を促進する2018
- Author(s)
  松永紘明、岩下未咲、山下明子、新城尊徳、鶴田満大、西村英紀
- Organizer
  第61回春季日本歯周病学会学術大会
- Data Source
  KAKENHI-PROJECT-16K11835
[Presentation] 脂肪組織Complement factor Bは脂肪細胞の成熟および肥満を促進する2017
- Author(s)
  松永紘明、岩下未咲、新城尊徳、山下明子、鶴田満大、西村英紀
- Organizer
  日本歯周病学会九州五大学・日本臨床歯周病学会九州支部2017年度合同研修会
- Data Source
  KAKENHI-PROJECT-16K11835
[Presentation] 薬剤性歯肉増殖症におけるspock-1の役割2017
- Author(s)
  Rehab Alshargabi, 高野愛子, 山下明子，豊田啓介, 岩下未咲，佐野朋美，竹下正章，鶴田満大，松永紘明，眞田大樹, 相田宜利，讃井彰一，西村英紀
- Organizer
  平成29年度日本歯周病学会60周年記念京都大会
- Data Source
  KAKENHI-PROJECT-15K11393
[Presentation] Epicatechin down-regulates inflammatory genes in adipocytes co-cultured with endotoxin-activated macrophages.2017
- Author(s)
  Akiko Yamashita, Tomomi Sano, Shintaro Nagayasu, Misaki Iwashita, Takanori Shinjo, Fusanori Nishimura
- Organizer
  95th IADR General Session
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11393
[Presentation] 脂肪組織Complement factor Bが炎症および代謝制御に及ぼす影響2017
- Author(s)
  松永紘明、岩下未咲、山下明子、新城尊徳、鶴田満大、西村英紀
- Organizer
  第60回日本歯周病学会春季学術大会
- Data Source
  KAKENHI-PROJECT-16K11835
[Presentation] The effect of cathepsin-B deficiency on gingival overgrowth in mice.2016
- Author(s)
  Akiko Yamashita, Alshargabi Rehab Yahya Fara Sallam, Takanori Shinjyo, Misaki Iwashita, Hiroaki Matsunaga, Mitsudai Tsuruta, Yoko Hashimoto, Fusanori Nishimura
- Organizer
  94th IADR General Session
- Place of Presentation
  Ｓｅｏｕｌ，Ｒｅｐｕｂｌｉｃ　ｏｆ　Ｋｏｒｅａ
- Year and Date
  2016-06-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K11393
[Presentation] 脂肪組織Complement factor Bが炎症および代謝制御に及ぼす影響2016
- Author(s)
  松永紘明、山下明子、岩下未咲、新城尊徳、鶴田満大、西村英紀
- Organizer
  第59回日本歯周病学会春季学術大会
- Place of Presentation
  かごしま県民交流センター
- Year and Date
  2016-05-19
- Data Source
  KAKENHI-PROJECT-16K11835
[Presentation] The effect of cathepsin-B deficiency on gingival overgrowth in mice.2016
- Author(s)
  Alshargabi Rehab Yahya Fara Sallam, Akiko Yamashita, Takanori Shinjyo, Misaki Iwashita, Hiroaki Matsunaga, Mitsudai Tsuruta, Yoko Hashimoto, Fusanori Nishimura
- Organizer
  第59回春季日本歯周病学会学術大会
- Place of Presentation
  鹿児島市
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K11393
[Presentation] 多毛症を合併した先天性歯肉増殖症患者由来歯肉線維芽細胞のカテプシン活性の検討2013
- Author(s)
  荒川真、半井英雄、山下明子、岩本義博、鈴木茂樹、西村英紀
- Organizer
  日本歯周病学会2013年度春季学術大会(第56回)
- Place of Presentation
  タワーホール船堀(東京)
- Data Source
  KAKENHI-PROJECT-23593059
[Presentation] 多毛症を合併した先天性歯肉増殖症患者由来歯肉線維芽細胞のカテプシン活性の検討2013
- Author(s)
  荒川真、半井英雄、山下明子、岩本義博、鈴木茂樹、西村英紀
- Organizer
  日本歯周病学会
- Place of Presentation
  タワーホール船堀（東京）
- Data Source
  KAKENHI-PROJECT-23593059
[Presentation] 13：局所の慢性炎症が惹起するインスリン抵抗性などのメタボリックシンドロームに関わるmiRNAの網羅的解析2012
- Author(s)
  山下明子
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-24792331
[Presentation] マクロファージと共存する脂肪細胞を LPS 刺激した際に発現変動する miRNA の網羅的解析2012
- Author(s)
  山下明子, 岩下未咲, 鈴木茂樹, 櫛山暁史, 安孫子宜光, 浅野知一郎, 西村英紀
- Organizer
  第55回日本糖尿病学会年次学術集会
- Place of Presentation
  横浜
- Year and Date
  2012-05-18
- Data Source
  KAKENHI-PROJECT-24792331
[Presentation] 歯髄細胞が産生するTNFα誘導因子の探索2012
- Author(s)
  永安慎太郎、鈴木茂樹、小武家誠司、山下明子、安孫子宜光、西村英紀
- Organizer
  第137回日本歯科保存学会秋季学術大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-23659889
[Presentation] 2型糖尿病患者におけるココアフラボノールの心血管イベント抑制効果機序の検討～脂肪細胞・マクロファージ相互作用の観点から～2011
- Author(s)
  永安慎太郎, 山下明子, 他
- Organizer
  第54回日本歯周病学会春季学術大会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] ココアフラボノイドの心血管イベント抑制効果機序の解析―脂肪細胞マクロファージ相互作用の観点から2011
- Author(s)
  山下明子, 他
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] ココアフラボノイドの心血管イベント抑制効果機序の解析-脂肪細胞マクロファージ相互作用の観点から2011
- Author(s)
  山下明子, 他
- Organizer
  第54回日本糖尿病学会年次学術集会
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] 2型糖尿病患者におけるココアフラボノールの心血管イベント抑制効果機序の検討～脂肪細胞・マクロファージ相互作用の観点から～2011
- Author(s)
  永安慎太郎, 山下明子, 他
- Organizer
  第54回日本歯周病学会春季学術大会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] Adipose tissue inflammation and smoking synergistically suppress leptin expression in Japanese obese males : Potential mechanism of resistance to weight loss among obese smokers2011
- Author(s)
  Nagayasu S., Yamashita A., 他
- Organizer
  4th Hiroshima Conference on Education and Scienee in Dentistry
- Place of Presentation
  広島
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] 喫煙がレプチン産生に与える影響についての検討2011
- Author(s)
  永安慎太郎, 山下明子, 他
- Organizer
  第54回日本歯周病学会秋季学術大会
- Place of Presentation
  下関
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] フラボノイドによる歯髄炎症制御の応用～リン酸化プルランセメントを用いての検討2011
- Author(s)
  米廣純子,山下明子,永安慎太郎,西村英紀, 他
- Organizer
  第132回日本歯科保存学会春季学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-23659889
[Presentation] Periodontal disease may up-regulatestri glycerides in Japanese viaenhanced lipolysis2011
- Author(s)
  Nakarai H., Yamashita A., NishimuraF
- Organizer
  The 89^<th> Internationaland American Association forDental Research
- Place of Presentation
  SanDiego, U. S. A.
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] Fusanori Nishimura : Study on inhibitoryef fects of Cacao flavonol on arteriosclerosisby its anti-inflammatoryaction2011
- Author(s)
  Shintaro Nagayasu, Akiko Yamashita, Shigeki Suzuki, Yoshimitu Abiko
- Organizer
  3^<rd> International Workshop onBioDental Education and Research
- Place of Presentation
  Hiroshima
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] Adipose tissue inflammation and smoking synergistically suppress leptinexpression in Japanese obesemales : Potential mechanism of resistanceto weight loss among obesesmokers2010
- Author(s)
  Shintaro Nagayasu, Akiko Yamashita, et al
- Organizer
  4th Hiroshima Conferenceon Education and Science in Dentistry
- Place of Presentation
  Hiroshima
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] マクロファージはTNF-αを介して脂肪分解を誘導し,中性脂肪の上昇に関与する2010
- Author(s)
  半井英雄, 山下明子, 西村英紀
- Organizer
  第53回歯周病学会秋季学術大会
- Place of Presentation
  高松市
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] マクロファージはTNF-αを介して脂肪分解を誘導し中性脂肪の上昇に関与する2010
- Author(s)
  半井英雄, 山下明子, 他
- Organizer
  第53回日本歯周病学会秋季学術大会
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] 脂肪細胞はマクロファージと胸像ンすることでLPS刺激によって急性期タンパクSAAを高産生する2010
- Author(s)
  半井英雄, 山下明子, 他
- Organizer
  第53回日本糖尿病学会年次学術集会
- Place of Presentation
  岡山市
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] フラボノイドによる歯髄炎症制御の応用～リン酸化プルランセメントを用いての検討2010
- Author(s)
  米廣純子, 山下明子, 他
- Organizer
  第132回日本歯科保存学会春季学術大会
- Place of Presentation
  熊本
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] ココアフラボノールの心血管イベント抑制効果の機序の検討-脂肪細胞・マクロファージ相互作用の観点から2010
- Author(s)
  永安慎太郎, 山下明子, 西村英紀, 他
- Organizer
  第53回歯周病学会秋季学術大会
- Place of Presentation
  高松市
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] ココアフラボノールの心血管イベント抑制効果機序の検討.脂肪細胞・マクロファージ相互作用の観点から2010
- Author(s)
  永安慎太郎, 山下明子, 他
- Organizer
  第25回日本糖尿病合併症学会
- Place of Presentation
  大津
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] ココアフラボノールの心血管イベント抑制効果の機序の検討-脂肪細胞・マクロファージ相互作用の観点から2010
- Author(s)
  永安慎太郎, 山下明子, 他
- Organizer
  第53回日本歯周病学会秋季学術大会
- Place of Presentation
  高松
- Year and Date
  2010-09-19
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] 脂肪細胞はマクロファージと共存することでLPS刺激によって急性期タンパクSAAを高産生する2010
- Author(s)
  半井英雄, 山下明子, 他
- Organizer
  第53回日本糖尿病学会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] Periodontal tissue destructionis associated with high triglyceridesin Japanese2010
- Author(s)
  Yamashita A, et al
- Organizer
  Periodontal tissue destructionis associated with high triglyceridesin Japanese
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] Periodontal tissue destruction is associated with high triglycerides in Japanese2010
- Author(s)
  Akiko Yamashita, Fusanori Nishimura, et.al.
- Organizer
  88^<th> IADR
- Place of Presentation
  Barcelona, Spain
- Data Source
  KAKENHI-PROJECT-22792086
[Presentation] マクロファージと共存する脂肪細胞はLPS刺激によってtoll-like receptorを介するシグナルを増強する分子群を産生する2009
- Author(s)
  山下明子, 他
- Organizer
  第52回日本糖尿病学会学術大会
- Place of Presentation
  大阪市
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] マクロファージと共存する脂肪細胞はLPS刺激によって toll-like receptor を介するシグナルを増強する分子群を産生する2009
- Author(s)
  熊本園子, 山下明子, 他
- Organizer
  第52回日本歯周病学会春季学術大会
- Place of Presentation
  岡山コンベンションセンター(岡山県岡山市)
- Year and Date
  2009-05-15
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 低濃度LPS刺激条件下の脂肪細胞・マクロファージ共培養系における脂肪細胞の網羅的遺伝子発現解析2009
- Author(s)
  山下明子, 他
- Organizer
  第130回日本歯科保存学会春季学術大会
- Place of Presentation
  札幌市
- Year and Date
  2009-06-12
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] マクロファージと共存する脂肪細胞はLPS刺激によって toll-like receptor を介するシグナルを増強する分子群を産生する2009
- Author(s)
  山下明子, 他
- Organizer
  第52回日本糖尿病学会学術大会
- Place of Presentation
  大阪国際会議場(大阪府大阪市)
- Year and Date
  2009-05-22
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 低濃度LPS刺激条件下の脂肪細胞・マクロファージ共培養系における脂肪細胞の網羅的遺伝子発現解析2009
- Author(s)
  山下明子, 他
- Organizer
  第130回日本歯科保存学会春季学術大会
- Place of Presentation
  北海道コンベンションセンター(北海道札幌市)
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] DNA microarray analyses of LPS-stimulated adipocytes co- cultured with macrophages2009
- Author(s)
  Akiko Yamashita, et al
- Organizer
  87th the International Association for Dental Research
- Place of Presentation
  Miami, U.S. A
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] マクロファージと共存する脂肪細胞はLPS刺激によってtoll-like receptorを介するシグナルを増強する分子群を産生する2009
- Author(s)
  熊本園子, 山下明子, 他
- Organizer
  第52回日本歯周病学会春季学術大会
- Place of Presentation
  岡山市
- Year and Date
  2009-05-16
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] DNA microarray analyses of LPS-stimulated adipocytes co-cultured with macrophages2009
- Author(s)
  山下明子
- Organizer
  87^<th> the International Association for Dental Research
- Place of Presentation
  Maiami, U.S.A
- Year and Date
  2009-04-04
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] マクロファージと共存する脂肪細胞の急性期タンパク産生性はLPS刺激によって増強する2009
- Author(s)
  半井英雄, 山下明子, 他
- Organizer
  第52回日本歯周病学会秋季学術大会
- Place of Presentation
  宮崎観光ホテル(宮崎県宮崎市)
- Year and Date
  2009-10-11
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] マクロファージと共存する脂肪細胞の急性期タンパク産生性はLPS刺激によって増強する2009
- Author(s)
  半井英雄, 山下明子, 他
- Organizer
  第52回日本歯周病学会秋季学術大会
- Place of Presentation
  宮崎市
- Year and Date
  2009-10-11
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] Cytokine Profile Produced from LPS- stimulated Macrophage- Adipocyte Co-cultures2008
- Author(s)
  Akiko Yamashita, et al
- Organizer
  86th The International Association for Dental Research
- Place of Presentation
  tront, Canada
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 歯周炎症がメタボリックシンドロームの病態に及ぼす影響を判定するための検査指標の確立を目指した基礎研究2008
- Author(s)
  山下明子, 他
- Organizer
  第1回日本口腔検査学会総会・学術大会
- Place of Presentation
  東京都
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 低濃度LPSにより脂肪細胞・マクロファージ共培養系から産生される分子のサイトカインアレイ解析2008
- Author(s)
  山下明子
- Organizer
  第51回春季日本歯周病学会学術大会
- Place of Presentation
  大宮ソニックシティ(埼玉県さいたま市)
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 脂肪細胞-マクロファージ共培養系をLPS刺激することによって脂肪細胞で発現量が変動する遺伝子群の網羅的解析2008
- Author(s)
  山下明子
- Organizer
  第51回秋季日本歯周病学会学術大会
- Place of Presentation
  四日市市文化会館(三重県四日市市)
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 低濃度LPSにより脂肪細胞・マクロファージ共培養系から産生される分子のサイトカインアレイ解析2008
- Author(s)
  山下明子, 他
- Organizer
  第51回春季日本歯周病学会学術大会
- Place of Presentation
  さいたま市
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 脂肪細胞-マクロファージ相互作用から捉えた, 肥満症における炎症の増幅機序の解明2008
- Author(s)
  山下明子, 他
- Organizer
  第41回広島大学歯学会総会
- Place of Presentation
  広島市
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 脂肪細胞-マクロファージ共培養系をLPS刺激することによって脂肪細胞で発現量が変動する遺伝子群の網羅的解析2008
- Author(s)
  山下明子, 他
- Organizer
  第51回秋季日本歯周病学会学術大会
- Place of Presentation
  三重県四日市市
- Year and Date
  2008-10-19
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 歯周炎症がメクボリックシンドロームの病態に及ぼす影響を判定するための検査指標の確立を目指した基礎研究2008
- Author(s)
  山下明子
- Organizer
  第1回日本口腔検査学会総会・学術大会
- Place of Presentation
  東京歯科大学水道橋校舎血脇記念ホール(東京都千代田区)
- Year and Date
  2008-08-23
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] 脂肪細胞-マクロファージ相互作用から捉えた, 肥満症における炎症の増幅機序の解明2008
- Author(s)
  山下明子
- Organizer
  第41回広島大学歯学会総会
- Place of Presentation
  広島大学歯学部大講義室(A棟6階)(広島県広島市)
- Year and Date
  2008-06-15
- Data Source
  KAKENHI-PROJECT-20890143
[Presentation] Cytokine Profile Produced from LPS-stimulated Macrophage-Adipocyte Co-cultures2008
- Author(s)
  Akiko Yamashita
- Organizer
  86^<th> The International Association for Dental Research
- Place of Presentation
  トロント, カナダ
- Year and Date
  2008-07-04
- Data Source
  KAKENHI-PROJECT-20890143

1. NISHIMURA Fusanori (80208222)

# of Collaborated Projects: 9 results

# of Collaborated Products: 54 results
2. Iwashita Misaki (80611326)

# of Collaborated Projects: 4 results

# of Collaborated Products: 31 results
3. SUZUKI Shigeki (30549762)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. ABIKO Yoshimitsu (70050086)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
5. 浅野知一郎 (70242063)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. 佐野朋美 (50782075)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
7. ARAKAWA Makoto (60379881)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 大山秀樹 (90280685)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中西博 (20155774)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 讃井彰一 (70507780)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. FUKUDA Takao

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
12. 石丸直澄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 新城尊徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Yamashita Akiko 山下 明子

YAMASHITA Akiko 山下 明子

Research Projects

Research Products

Co-Researchers

miRNAを標的とした薬剤性歯肉増殖症新規治療薬の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

歯肉増殖症や肥満に関わる新規分子SPOCK1のシグナリング経路の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The elucidation of the pathophysiology of gingival overgrowth.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

New direction in periodontal medicine: Association of periodontal inflammation with energy metabolism

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of complement factor B on insulin resistance-related disease

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

the unravelling of the role of cathepsin in gingival overgrowthPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular basis for periodontal medicine based on the interaction between infiltrated inflammatory cells and resident cells.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Basic study aimed at the control of insulin resistance induced periodontal inflammation that target miRNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of patients with gingival hyperplasia and hypertrichosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Comprehensive analysis of the molecules up- or down- regulataed in dental pulp cells co-cultured with macrophages

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Global analysis of adipocytes co-cultured with macrophages treated with anti-inflammatory substancePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The basic and clinical study of the relevance of periodontal disease and metabolic syndrome.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 4. 高齢者・有病者の歯内治療 糖尿病とエンド―ぺリオ, 興地隆史、井澤常泰、石井信之、木ノ本喜史 編集「DENTAL DIAMOND 増刊号ライフステージと歯内療法 歯の長期保存のために」2013

Author(s)

Publisher

Yamashita Akiko 山下明子

YAMASHITA Akiko 山下明子

[Book] 4. 高齢者・有病者の歯内治療糖尿病とエンド―ぺリオ, 興地隆史、井澤常泰、石井信之、木ノ本喜史編集「DENTAL DIAMOND 増刊号ライフステージと歯内療法歯の長期保存のために」2013