ishii takashi 石井健士

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Ishii Takashi 石井健士

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Researcher Number	70516731
Other IDs
Affiliation (Current)	2025: 鎌倉女子大学, 家政学部, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2022: 鎌倉女子大学, 家政学部, 准教授 2020: 福岡歯科大学, 口腔歯学部, 講師 2016 – 2018: 福岡歯科大学, 口腔歯学部, 講師 2014 – 2015: 福岡歯科大学, 歯学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Molecular biology Except Principal Investigator Risk sciences of radiation and chemicals
Keywords	Principal Investigator AUF1 / 8-oxoG / 酸化損傷 / 老化 / 神経変性疾患 / PCBP1 / アポトーシス / RNA / 酸化ストレス / RNA結合タンパク質 … More / RNA分解 / PCBP2 / Auf1 / 疾患 / 酸化RNA / mRNA分解 / mRNA / ８－オキソグアニン … More Except Principal Investigator Mth1 / mutT / Auf1 / RNAの分解 / 8-オキソグアニン / 酸化RNA / ノックアウト細胞株 / ヌクレオチド代謝 / 酸化ヌクレオチド / アポトーシス / ８ーオキソグアニン / RNA 酸化 / 酸化ストレス Less

Initiation mechanisms of apoptosis for elimination of oxiditively damaged RNAPrincipal Investigator
- Principal Investigator
  
  Ishii Takashi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  Kamakura Women's University
  Fukuoka Dental College
Research for mechanisms of control in gene expression under oxidative stressPrincipal Investigator
- Principal Investigator
  
  Ishii Takashi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Molecular biology
- Research Institution
  Fukuoka Dental College
Cell death mechanism by RNA oxidative signal transduction
- Principal Investigator
  
  Sekiguchi Takeshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Risk sciences of radiation and chemicals
- Research Institution
  Kyushu University

All 2022 2021 2020 2018 2017 2016 2015

All Journal Article Presentation

[Journal Article] Involvement of Gtr1p in the oxidative stress response in yeast Saccharomyces cerevisiae2022
- Author(s)
  Sekiguchi Takeshi、Ishii Takashi、Kamada Yoshiaki、Funakoshi Minoru、Kobayashi Hideki、Furuno Nobuaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 598 Pages: 107-112
- DOI
  10.1016/j.bbrc.2022.02.016
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K06668, KAKENHI-PROJECT-19K06740, KAKENHI-PROJECT-20K06495
[Journal Article] WDR35 is involved in subcellular localization of acetylated tubulin in 293T cells2021
- Author(s)
  Sekiguchi Takeshi、Ishii Takashi、Kobayashi Hideki、Furuno Nobuaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 547 Pages: 169-175
- DOI
  10.1016/j.bbrc.2021.01.092
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06495, KAKENHI-PROJECT-19K06740
[Journal Article] PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions2020
- Author(s)
  Ishii Takashi、Igawa Tatsuhiro、Hayakawa Hiroshi、Fujita Tsugumi、Sekiguchi Mutsuo、Nakabeppu Yusaku
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 295 Issue: 34 Pages: 12247-12261
- DOI
  10.1074/jbc.ra119.011870
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K06495
[Journal Article] Specific binding of PCBP1 to heavily oxidized RNA to induce cell death2018
- Author(s)
  Ishii Takashi、Hayakawa Hiroshi、Igawa Tatsuhiro、Sekiguchi Takeshi、Sekiguchi Mutsuo
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 115 Issue: 26 Pages: 6715-6720
- DOI
  10.1073/pnas.1806912115
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K07260
[Journal Article] Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells.2015
- Author(s)
  Ishii T, Hayakawa H, Sekiguchi T, Adachi N, Sekiguchi M.
- Journal Title
  
  Free Radic Biol Med.
  
  Volume: 79 Pages: 109-116
- DOI
  10.1016/j.freeradbiomed.2014.11.018
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24310149, KAKENHI-PROJECT-24570160, KAKENHI-PROJECT-26340040, KAKENHI-PROJECT-26670031
[Presentation] PCBP2 is down regulated in degenerating neurons and rarely observed in skein-like inclusions in ALS2022
- Author(s)
  吉村基、本田裕之、笹ケ迫直一、森慎一郎、石井健士、二宮利治、磯部紀子、岩城徹
- Organizer
  第６３回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K06495
[Presentation] RNAの酸化損傷に対する生体防御機構2020
- Author(s)
  石井　健士
- Organizer
  福岡歯科大学学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06495
[Presentation] PCBP1タンパク質は酸化損傷RNA結合因子として機能する2018
- Author(s)
  石井健士
- Organizer
  日本遺伝学会
- Data Source
  KAKENHI-PROJECT-16K07260
[Presentation] Heavily oxidized RNA induces apoptosis2018
- Author(s)
  Takashi Ishii
- Organizer
  Beijing Symposium on Genetic Stability and Accurate Gene Expression under Oxidative Stress
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07260
[Presentation] PCBP1タンパク質は重度の酸化損傷を受けたRNAを認識して細胞死を誘導する2018
- Author(s)
  石井健士
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K07260
[Presentation] 酸化損傷を受けたRNA鎖に結合する新規因子の同定2017
- Author(s)
  石井健士
- Organizer
  日本分子生物学会
- Data Source
  KAKENHI-PROJECT-16K07260
[Presentation] Human proteins that recognize oxidative RNA damage.2017
- Author(s)
  Hayakawa, H., Ishii, T., Sekiguchi, M.
- Organizer
  Gordon Research Conf. Oxidative Stress and Disease
- Place of Presentation
  Lucca, Italy
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 酸化損傷mRNAの代謝に関わる新規因子の探索2016
- Author(s)
  石井健士
- Organizer
  日本分子生物学会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-16K07260
[Presentation] 酸化損傷mRNAの代謝に関わる新規因子の探索2016
- Author(s)
  石井健士、早川浩、関口猛、関口睦夫
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 毒性物質の排出における出芽酵母Gtr1タンパク質の働き2016
- Author(s)
  関口猛、石井健士、早川浩、古野伸明、小林英紀、関口睦夫
- Organizer
  第39回日本分子生物学会年
- Place of Presentation
  横浜
- Year and Date
  2016-11-30
- Data Source
  KAKENHI-PROJECT-26340040
[Presentation] 遺伝子破壊細胞株を用いたヒトNudix ファミリータンパク質の機能解析.2015
- Author(s)
  橋口一成、石井健士、早川浩、関口睦夫.
- Organizer
  第38回日本分子生物学会第88回日本生化学会大会合同大会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26340040

1. Sekiguchi Takeshi (60187846)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. 早川浩 (70150422)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
3. 伊東理世子 (10140865)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 関口睦夫 (00037342)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
5. 足立典隆

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 鎌田芳彰

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ishii takashi 石井 健士

Ishii Takashi 石井 健士

Research Projects

Research Products

Co-Researchers

Initiation mechanisms of apoptosis for elimination of oxiditively damaged RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for mechanisms of control in gene expression under oxidative stressPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cell death mechanism by RNA oxidative signal transduction

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Involvement of Gtr1p in the oxidative stress response in yeast Saccharomyces cerevisiae2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] WDR35 is involved in subcellular localization of acetylated tubulin in 293T cells2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] PCBP1 and PCBP2 both bind heavily oxidized RNA but cause opposing outcomes, suppressing or increasing apoptosis under oxidative conditions2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Specific binding of PCBP1 to heavily oxidized RNA to induce cell death2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of Auf1 in elimination of oxidatively damaged messenger RNA in human cells.2015

Author(s)

Journal Title

DOI

Data Source

[Presentation] PCBP2 is down regulated in degenerating neurons and rarely observed in skein-like inclusions in ALS2022

Author(s)

Organizer

Data Source

[Presentation] RNAの酸化損傷に対する生体防御機構2020

Author(s)

Organizer

Data Source

[Presentation] PCBP1タンパク質は酸化損傷RNA結合因子として機能する2018

Author(s)

Organizer

Data Source

[Presentation] Heavily oxidized RNA induces apoptosis2018

Author(s)

Organizer

Data Source

[Presentation] PCBP1タンパク質は重度の酸化損傷を受けたRNAを認識して細胞死を誘導する2018

Author(s)

Organizer

Data Source

[Presentation] 酸化損傷を受けたRNA鎖に結合する新規因子の同定2017

Author(s)

Organizer

Data Source

[Presentation] Human proteins that recognize oxidative RNA damage.2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] 酸化損傷mRNAの代謝に関わる新規因子の探索2016

Author(s)

ishii takashi 石井健士

Ishii Takashi 石井健士