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Kaimori Jun-Ya  貝森 淳哉

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KAIMORI Junya  貝森 淳哉

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Researcher Number 70527697
Affiliation (Current) 2025: 大阪大学, 大学院医学系研究科, 招へい教授
Affiliation (based on the past Project Information) *help 2023 – 2024: 大阪大学, 大学院医学系研究科, 招へい教授
2022: 大阪大学, 大学院医学系研究科, 寄附講座准教授
2021: 大阪大学, 医学系研究科, 寄附講座准教授
2016 – 2018: 大阪大学, 医学系研究科, 寄附講座准教授
2016: 大阪大学, 医学(系)研究科(研究院), 准教授 … More
2013 – 2016: 大阪大学, 医学(系)研究科(研究院), 寄附講座准教授
2014 – 2015: 大阪大学, 大学院医学系研究科, 寄附講座准教授
2014: 大阪大学, 医学(系)研究科(研究院), 准教授
2012: 大阪大学, 医学(系)研究科(研究院), 准教授
2011: 大阪大学, 医学系・研究科, 寄附講座准教授
2009 – 2011: Osaka University, 医学系研究科, 寄附講座准教授 Less
Review Section/Research Field
Principal Investigator
Kidney internal medicine / Basic Section 53040:Nephrology-related
Except Principal Investigator
Urology / General internal medicine(including psychosomatic medicine)
Keywords
Principal Investigator
Enac / ラミニン / 細胞外マトリックス / 菲薄基底膜病 / 血尿 / 遺伝性腎疾患 / ankyrin / 遺伝性疾患 / Ankyrin 3 / 高血圧 … More / ankyrin-3 / 低マグネシウム血症 / 低カリウム血症 / 高血圧症 / EnaC / Kv1.1 / ANK3 / 遺伝性高血圧症 / 低K血症 / 低Mg血症 / 腎臓学 / 尿細管間質腎炎 / 家族性疾患 / 腎臓内科 / 全エクソーム解析 / 次世代シークエンサー / 家族性尿細管間質腎炎 / ER stress / transgenic mouse / 細胞内凝集 / 小胞体ストレス / VNTR / MUC1 / ADTKD / cell hypertrophy / 転写抑制因子 / 転写促進因子 / Chip-seq / epigeneticcs / histone acetylation / gene expression / histone modification / epigenome / epigenetics / Smurf1, 2 / lipid raft / NEDD4-2 / endocytosis / TGF-b / Lipid raft / Smurf1,2 / Rap1B / RhoA / Polyductin / ARPKD / 細胞内情報伝達 / 腎臓 / 発現制御 / 遺伝子 … More
Except Principal Investigator
腎移植 / MRI / 臓器移植 / 免疫抑制療法 / 抗CD70抗体 / 腎臓繊維化 / DTI MRI / DTI / 腎繊維化 / 糖尿病性腎症 / エピジェネティクス / 腎臓内科 / エピジェネティクス / エピジェネティック / 細胞肥大 / ヒストン修飾 / エピジェネティク / 腎障害 / SPG / siCD40 / siCD40/SPG複合体 / CD40 siRNA / 免疫寛容 / 移植腎繊維化 / q space imaging / 拡散テンソルMRI / 拡散MRI / BOLD MRI / 組織障害 / 移植グラフト / 臓器障害 Less
  • Research Projects

    (10 results)
  • Research Products

    (33 results)
  • Co-Researchers

    (11 People)
  •  新規遺伝子変異による菲薄基底膜病の分子病態学的研究Principal Investigator

    • Principal Investigator
      貝森 淳哉
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  molecular genetic analyses of a family with hereditary hypo Mg, hypo K ,and hypertensionPrincipal Investigator

    • Principal Investigator
      Kaimori Jun-Ya
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 53040:Nephrology-related
    • Research Institution
      Osaka University
  •  a molecular biology study of Autosomal dominant tubulointerstitial kidney disease by using mutated MUC1 cDNA sequence identified in our own patient family.Principal Investigator

    • Principal Investigator
      Kaimori Junya
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  Development of next-generation immunosuppressive therapy in organ transplantation using anti-CD70 antibody

    • Principal Investigator
      Ichimaru Naotsugu
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Osaka University
  •  Development of non-invasive bioimaging techniques for evaluation of transplantation related kidney injury.

    • Principal Investigator
      Shiro Takahara
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Osaka University
  •  Development of a new therapy by regulating histone acetylation

    • Principal Investigator
      ISAKA Yoshitaka
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      General internal medicine(including psychosomatic medicine)
    • Research Institution
      Osaka University
  •  Permanent acceptance of allografts with CD40 siRNA by use of a novel polysaccharide siRNA delivery system.

    • Principal Investigator
      ICHIMARU Naotsugu
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Urology
    • Research Institution
      Osaka University
  •  Basic research of new epigenetic marker, H4K20acPrincipal Investigator

    • Principal Investigator
      Kaimori Jun-Ya
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University
  •  establishment of a new evaluation technique by none envasive MRI

    • Principal Investigator
      TAKAHARA Shiro
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Urology
    • Research Institution
      Osaka University
  •  the research of PKHD1 product FPC in cell signaling related to major ARPKD phenotypes.Principal Investigator

    • Principal Investigator
      KAIMORI Junya
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Kidney internal medicine
    • Research Institution
      Osaka University

All 2022 2018 2017 2016 2014 2013 2010 2009

All Journal Article Presentation Book

  • [Book] 腎と透析ベッドサイド事典2018

    • Author(s)
      貝森淳哉
    • Total Pages
      472
    • Publisher
      東京医学社
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Journal Article] 家族性尿細管腎炎2018

    • Author(s)
      貝森淳哉
    • Journal Title

      別冊Bio Clinica

      Volume: 7(4) Pages: 104-109

    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Journal Article] 家族性尿細管間質腎炎2017

    • Author(s)
      貝森淳哉
    • Journal Title

      Bio Clinica

      Volume: 32 Pages: 71-76

    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Journal Article] Diffusion Tensor Imaging MRI with spin echo sequence and long duration measurement was identified for evaluation of renal fibrosis in rat fibrosis model2017

    • Author(s)
      Jun-Ya Kaimori, Yoshitaka Isaka, Masaki Hatanaka, Satoko Yamamoto, Naotsugu Ichimaru, Akihiko Fujikawa, Hiroshi Shibata, Akira Fujimori, Sosuke Miyoshi, Takashi Yokawa, Kagayaki Kuroda, Toshiki Moriyama, Hiromi Rakugi, Shiro Takahara
    • Journal Title

      Transplantation Proceedings

      Volume: 49 Issue: 1 Pages: 145-152

    • DOI

      10.1016/j.transproceed.2016.10.014

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K10640
  • [Journal Article] Analysis of an ADTKD family with a novel frameshift mutation in MUC1 reveals characteristic features of mutant MUC1 protein2017

    • Author(s)
      Satoko Yamamoto, Jun-Ya Kaimori, Takuji Yoshimura, Tomoko Namba, Atsuko Imai, Kaori Kobayashi, Ryoichi Imamura, Naotsugu Ichimaru, Kazuto Kato, Akihiro Nakaya, Shiro Takahara, Yoshitaka Isaka
    • Journal Title

      Nephrology Dialysis Transplantation

      Volume: in press

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Journal Article] Analysis of an ADTKD family with a novel frameshift mutation in MUC1 reveals characteristic features of mutant MUC1 protein2017

    • Author(s)
      Yamamoto S, Kaimori J, Yoshimura T, Namba T, Imai A, Kobayashi K, Imamura R, Ichimaru N, Kato K, Nakaya A, Takahara S, & Isaka Y
    • Journal Title

      Nephrology Dialysis Transplantation

      Volume: 32 Issue: 12 Pages: 2010-2007

    • DOI

      10.1093/ndt/gfx083

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07222, KAKENHI-PROJECT-16K09615, KAKENHI-PROJECT-17K08632, KAKENHI-PROJECT-16K19404
  • [Journal Article] Visualization of kidney fibrosis in diabetic nephropathy by long diffusion tensor imaging MRI with spin-echo sequence2017

    • Author(s)
      Kaimori JY, Isaka Y, Hatanaka M, Yamamoto S, Ichimaru N, Fujikawa A, Shibata H, Fujimori A, Miyoshi S, Yokawa T, Kuroda K, Moriyama T, Rakugi H, Takahara S
    • Journal Title

      Scientific Reports

      Volume: 7 Issue: 1 Pages: 5731-5731

    • DOI

      10.1038/s41598-017-06111-4

    • Data Source
      KAKENHI-PROJECT-15K10640
  • [Journal Article] 家族性尿細管間質腎炎2017

    • Author(s)
      貝森淳哉、高原史郎、猪阪善隆
    • Journal Title

      細胞

      Volume: 49 Pages: 475-478

    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Journal Article] Histone H4 lysine 20 acetylation is associated with gene repression in human cells.2016

    • Author(s)
      Kaimori, J. Y., Maehara, K., Hayashi-Takanaka, Y., Harada, A., Fukuda, M., Yamamoto, S., Ichimaru, N., Umehara, T., Yokoyama, S., Matsuda, R., Ikura, T., Nagao, K., Obuse, C., Nozaki, N., Takahara, S., Takao, T., Ohkawa, Y., Kimura, H., and Isaka, Y.
    • Journal Title

      Sci Rep.

      Volume: 6 Issue: 1 Pages: 24318-24318

    • DOI

      10.1038/srep24318

    • NAID

      120005770760

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K06942, KAKENHI-PUBLICLY-15H01462, KAKENHI-PLANNED-25116005, KAKENHI-PROJECT-25503002, KAKENHI-PROJECT-25670410, KAKENHI-PROJECT-26291071, KAKENHI-PUBLICLY-16H01219, KAKENHI-PUBLICLY-16H01307, KAKENHI-PUBLICLY-16H01550, KAKENHI-PUBLICLY-16H01577, KAKENHI-PLANNED-25116010, KAKENHI-PROJECT-16H04739, KAKENHI-PROJECT-26281020, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26293166, KAKENHI-PROJECT-15K12203, KAKENHI-PROJECT-26650002, KAKENHI-PROJECT-15K18457, KAKENHI-PROJECT-16K18479, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-25116004
  • [Journal Article] Histone H4 lysine 20 acetylation is associated with gene repression in human cells.2016

    • Author(s)
      Kaimori J, Maehara K, Hayashi-Takanaka Y, Harada A, Fukuda M, Yamamoto S, Ichimaru N, Umehara T, Yokoyama S, Matsuda R, Ikura T, Nagao K, Obuse C, Nozak Ni, akahara S, Takao T, Ohkawa Y, Kimura H, and Isaka Y
    • Journal Title

      Scientific Reports

      Volume: in press

    • NAID

      120005770760

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-26293166
  • [Journal Article] 心停止後ラット腎臓のfunctional MRIを用いた詳細な障害の評価と腎移植後グラフト予後予測可能性2014

    • Author(s)
      貝森淳哉、岩井聡美、小林英司、畑中雅喜、津田秀年、小尾佳嗣、奥見雅由、矢澤浩治、市丸直嗣、楽木宏美、野々村祝夫、猪阪善隆、高原史郎
    • Journal Title

      Organ Biology

      Volume: 21(2) Pages: 179-181

    • NAID

      130004715801

    • Open Access
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Journal Article] Non-Invasive Magnetic Resonance Imaging in Rats for Prediction of the Fate of Grafted Kidneys from Cardiac Death Donors2013

    • Author(s)
      J Kaimori, S Iwai, M Hatanaka, T Teratani, Y Obi,H Tsuda, Y Isaka, T Yokawa, K Kuroda, N Ichimaru,MOkumi, K Yazawa, H Rakugi, N Nonomura, S Takahara, E Kobayashi
    • Journal Title

      PLOS ONE

      Volume: Volume 8 | Issue 5 |

    • NAID

      130004715801

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Presentation] 低Mg・低K血症を伴う遺伝性高血圧の新規責任遺伝子ANK-3の同定とその変異の機能解析2022

    • Author(s)
      梶本幸男、坂口悠介、貝森淳哉、服部洸輝、朝比奈悠太、土井洋平、岡樹史、高橋篤史、猪阪善隆
    • Organizer
      臨床体液研究会
    • Data Source
      KAKENHI-PROJECT-21K08277
  • [Presentation] 低Mg・低K血症を伴う遺伝性高血圧の新規責任遺伝子ANK-3の同定とその変異の機能解析2022

    • Author(s)
      梶本幸男、坂口悠介、貝森淳哉、服部洸輝、朝比奈悠太、土井洋平、岡樹史、高橋篤史、猪阪善隆
    • Organizer
      第65回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-21K08277
  • [Presentation] 異常MUC1 transgenic mouseの解析で明らかとなった、ADTKD-MUC1が全身性疾患である可能性2018

    • Author(s)
      貝森淳哉
    • Organizer
      第9回腎不全研究会
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Presentation] 異常MUC1 transgenic mouseの解析で明らかとなった、ADTKD-MUC1が全身性疾患である可能性2018

    • Author(s)
      貝森淳哉
    • Organizer
      第26回嚢胞性腎疾患研究会
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Presentation] CME NPHとMCKDを見逃さないために MCKD症例2017

    • Author(s)
      貝森淳哉
    • Organizer
      第60回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Presentation] MCKD1の発症には変異MUC1遺伝子に対するナンセンス変異依存mRNA分解機構の破綻と小胞体ストレスが関与している2017

    • Author(s)
      山本聡子, 貝森淳哉, 高原史郎, 猪阪善隆
    • Organizer
      第60回日本腎臓学会学術総会
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Presentation] 糖尿病性腎症の存在下でも可能な、DTI MRIによる腎線維化撮影法の確立2017

    • Author(s)
      貝森淳哉,猪阪善隆,余川隆, 市丸直嗣,高原史郎
    • Organizer
      第43回日本移植学会学術総会
    • Data Source
      KAKENHI-PROJECT-15K10640
  • [Presentation] 腎疾患最終診断としての病理、質量分析、遺伝子診断2017

    • Author(s)
      貝森淳哉
    • Organizer
      第60回日本腎臓学会学術総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-16K09615
  • [Presentation] New Epigenetic Marker, H4K20ac Related to Transcriptional Suppression2013

    • Author(s)
      貝森淳哉
    • Organizer
      アメリカ腎臓学会
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-25670410
  • [Presentation] Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors2013

    • Author(s)
      貝森淳哉
    • Organizer
      アジア移植学会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Presentation] 次世代シークエンサーを用いた新規ヒストン修飾の研究2013

    • Author(s)
      貝森淳哉
    • Organizer
      日本腎臓学会
    • Place of Presentation
      東京国際フォーラム
    • Data Source
      KAKENHI-PROJECT-25670410
  • [Presentation] Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors2013

    • Author(s)
      貝森淳哉
    • Organizer
      アメリカ腎臓学会
    • Place of Presentation
      Atlanta, GA, USA
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Presentation] 移植腎臓live imaging : functional MRIとmultiphoton microscopy 2つのmodality2013

    • Author(s)
      貝森淳哉
    • Organizer
      日本移植学会
    • Place of Presentation
      京都国際会議場
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Presentation] Non-invasive magnetic resonance imaging in rats for prediction of the fate of grafted kidneys from cardiac death donors2013

    • Author(s)
      貝森淳哉
    • Organizer
      日本臓器保存生物医学会
    • Place of Presentation
      東京医科大学病院
    • Data Source
      KAKENHI-PROJECT-24659714
  • [Presentation] Pkhd1 deficiency identifies a nobel functional relationship between Fibrocystin/Polyductin and NEDD4 family E3 ligase mediated endocytosis, leading to ARPKD clinical symptoms.2010

    • Author(s)
      貝森淳哉
    • Organizer
      腎疾患と高血圧研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-03
    • Data Source
      KAKENHI-PROJECT-21591029
  • [Presentation] Pkhd1 deficiency identifies a nobel functional relationship between Fibrocystin/ Polyductin and NEDD4 family E3 ligase mediated endocytosis, leading to ARPKD clinical symptoms2010

    • Author(s)
      貝森淳哉
    • Organizer
      腎疾患と高血圧研究会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-03
    • Data Source
      KAKENHI-PROJECT-21591029
  • [Presentation] Pkhd1 deficiency identifies a novel functional relationship between FPC, Nedd4 ubiquitin ligase family-mediated endocytosis, TGF-beta signaling, and ENaC regulation2010

    • Author(s)
      貝森淳哉
    • Organizer
      米国腎臓学会
    • Place of Presentation
      米国Denver
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21591029
  • [Presentation] Pkhd1 deficiency identifies a novel functional relationship between FPC, Nedd4 ubiquitin ligase family-mediated endocytosis, TGF-beta signaling, and ENaC regulation.2010

    • Author(s)
      貝森淳哉
    • Organizer
      米国腎臓学会
    • Place of Presentation
      米国Denver
    • Year and Date
      2010-11-18
    • Data Source
      KAKENHI-PROJECT-21591029
  • [Presentation] Pkhd1 deficiency causes dysregulation in SMURFs and endocytosis, leading to cell-structural changes and enhanced TGF-beta signaling2010

    • Author(s)
      貝森淳哉
    • Organizer
      日本腎臓学会
    • Place of Presentation
      神戸
    • Year and Date
      2010-06-16
    • Data Source
      KAKENHI-PROJECT-21591029
  • [Presentation] Polyductin(PD1) deficiency causes dysregulation of Smurfs and altered endocytosis, resulting in cytostructural changes and TGF-b signaling defects2009

    • Author(s)
      貝森淳哉
    • Organizer
      日本腎臓学会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21591029
  • [Presentation] Polyductin (PD1) deficiency causes dysregulation of Smurfs and altered endocytosis, resulting in cytostructural changes and TGF-b signaling defacts2009

    • Author(s)
      貝森淳哉
    • Organizer
      第52回 日本腎臓学会学術総会
    • Place of Presentation
      パシフィコ横浜
    • Year and Date
      2009-06-04
    • Data Source
      KAKENHI-PROJECT-21591029
  • 1.  TAKAHARA Shiro (70179547)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 8 results
  • 2.  ISAKA Yoshitaka (00379166)
    # of Collaborated Projects: 7 results
    # of Collaborated Products: 11 results
  • 3.  ICHIMARU Naotsugu (70346211)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 4 results
  • 4.  KURODA Kagayaki (70205243)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 5.  LI Xiao-Kang (60321890)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  坂口 悠介 (80756817)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 2 results
  • 7.  KOBAYASHI Eiji (00245044)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  KIMURA Hiroshi (30241392)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  KOBAYASHI kaori
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  長尾 恒治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  中谷 明弘
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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