HIRAIWA Hideki 平岩秀樹

… Alternative Names

Researcher Number	70566976
Affiliation (Current)	2020: 名古屋大学, 医学部附属病院, 病院講師
Affiliation (based on the past Project Information) *help	2016 – 2020: 名古屋大学, 医学部附属病院, 病院講師 2010 – 2013: 名古屋大学, 医学部附属病院, 病院助教 2011 – 2012: 名古屋大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Orthopaedic surgery Except Principal Investigator Orthopaedic surgery / Basic Section 56020:Orthopedics-related / Surgery related to the biological and sensory functions and related fields / Rehabilitation science/Welfare engineering
Keywords	Principal Investigator 関節病学 / 軟骨代謝 / 加齢 / 変形性膝関節症 / 後期糖化最終生成物 Except Principal Investigator 変形性関節症 / 軟骨細胞 / microRNA / Drug repositioning / ADAMTS4 … More

Ｗｎｔ/βカテニン・ＡＤＡＭ１０阻害による新規作用機序の変性関節症治療薬の開発Ongoing
- Principal Investigator
  
  石黒直樹
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Nagoya University
Diagnosis of Motor function and improvement methods of motor function of community living elderly people using artificial intelligenceOngoing
- Principal Investigator
  
  長谷川幸治
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Kansai University of Welfare Sciences
変形性関節症における軟骨細胞の再プログラミングによる多分化能の獲得
- Principal Investigator
  
  酒井忠博
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Surgery related to the biological and sensory functions and related fields
- Research Institution
  Nagoya University
Development of a new drug for treating osteoarthritis caused by increased expression of Dkk1 molecule
- Principal Investigator
  
  Ishiguro Naoki
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
Establishment of a checkup method for early knee osteoarthritis using analyses of vibroarthrography from the knee joint
- Principal Investigator
  
  Ota Susumu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Seijoh University
Micro RNAs could modulate the reprogramming of osteoarthritic chondrocytes.
- Principal Investigator
  
  SAKAI TADAHIRO
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
The effect of advanced glycation end products to meniscal degeneration of osteoarthritic kneesPrincipal Investigator
- Principal Investigator
  
  HIRAIWA Hideki
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University
The pathological roles of micro RNAs in osteoarthritis
- Principal Investigator
  
  SAKAI Tadahiro
- Project Period (FY)
  2010 – 2011
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Nagoya University

All 2020 2019 2017 2016 2013 2012 2011

All Journal Article Presentation

[Journal Article] Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling2017
- Author(s)
  Miyamoto Kentaro、Ohkawara Bisei、Ito Mikako、Masuda Akio、Hirakawa Akihiro、Sakai Tadahiro、Hiraiwa Hideki、Hamada Takashi、Ishiguro Naoki、Ohno Kinji
- Journal Title
  
  PLOS ONE
  
  Volume: 12
- DOI
  10.1371/journal.pone.0184388
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K06707, KAKENHI-PROJECT-15H04840, KAKENHI-PROJECT-16K15661
[Journal Article] 小児膝伸展機構損傷後に膝蓋腱骨化を生じた２例2017
- Author(s)
  宮本健太郎，小田智之，黒河内和俊，高橋成夫，平岩秀樹，濱田恭，山下暁士，岸本烈純，土谷早穂，酒井忠博
- Journal Title
  
  JOSKAS
  
  Volume: 42(2) Pages: 364-365
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15661
[Journal Article] スポーツで受傷した膝複合靱帯損傷に総腓骨神経損傷を合併した２例2017
- Author(s)
  酒井忠博，平岩秀樹，濱田恭，小田智之，山下暁士，宮本健太郎，岸本烈純，土谷早穂，大羽宏樹，川村佑介
- Journal Title
  
  JOSKAS
  
  Volume: 42(2) Pages: 370-371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15661
[Journal Article] Coxitis kneeに対する人工膝関節置換術の治療成績2017
- Author(s)
  濱田恭, 平岩秀樹, 小田智之, 山下暁士, 宮本健太郎, 岸本烈純, 土谷早穂, 川村佑介, 大羽宏樹, 酒井忠博
- Journal Title
  
  JOSKAS
  
  Volume: 42(2) Pages: 296-297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15661
[Journal Article] 反復性肩関節脱臼に対する空気を用いた関節造影CTの診断能の検討2017
- Author(s)
  平岩秀樹, 酒井忠博, 濱田恭, 大野洋平, 小田智之, 山下暁士, 宮本健太郎, 岸本烈純, 土谷早穂, 大羽宏樹, 川村佑介
- Journal Title
  
  肩関節
  
  Volume: 41(3) Pages: 649-652
- NAID
  130006195195
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15661
[Journal Article] Hypoxia-inducible factor-2α induces expression of type X collagen and matrix metalloproteinases 13 in osteoarthritic meniscal cells2016
- Author(s)
  Ishizuka S,Sakai T,Hiraiwa H,Hamada T,Warren K,Ono Y,Nakashima M,Matsukawa T,Oda T,Takamatsu A,Yamashita S,Ishiguro N
- Journal Title
  
  Inflammation Research
  
  Volume: 65（６） Pages: 439-48
- DOI
  10.1007/s00011-016-0926-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15661
[Journal Article] Osteoarthritis-derived chondrocytes are a potential source of multipotent progenitor cells for cartilage tissue engineering.2016
- Author(s)
  Oda T, Sakai T, Hiraiwa H, Hamada T, Ono Y, Nakashima M, Ishizuka S, Matsukawa T, Yamashita S, Tsuchiya S, Ishiguro N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 479（３） Pages: 469-475
- DOI
  10.1016/j.bbrc.2016.09.085
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15661
[Journal Article] SURFACE MARKERS AND GENE EXPRESSION TO CHARACTERIZE THE DIFFERENTIATION OF MONOLAYER EXPANDED HUMAN ARTICULAR CHONDROCYTES2013
- Author(s)
  TAKASHI HAMADA, TADAHIRO SAKAI, HIDEKI HIRAIWA, MOTOSHIGE NAKASHIMA, YOHEI ONO, HIROHITO MITSUYAMA and NAOKI ISHIGURO
- Journal Title
  
  Nagoya J. Med. Sci
  
  Volume: 75 Pages: 101-111
- NAID
  120005227637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659672
[Journal Article] Chondrogenic capacity and alterations in hyaluronan synthesis of cultured human osteoarthritic chondrocytes2013
- Author(s)
  Ono Y, Sakai T, Hiraiwa H, Hamada T, Omachi T, Nakashima M, Ishizuka S, Matsukawa T, Knudson W, Knudson CB, Ishiguro N.
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 435(4) Pages: 733-739
- DOI
  10.1016/j.bbrc.2013.05.052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659672
[Journal Article] SURFACE MARKERS AND GENE EXPRESSION TO CHARACTERIZE THE DIFFERENTIATION OF MONOLAYER EXPANDED HUMAN ARTICULAR CHONDROCYTES,2013
- Author(s)
  TAKASHI HAMADA, TADAHIRO SAKAI, HIDEKI HIRAIWA, MOTOSHIGE NAKASHIMA, YOHEI ONO, HIROHITO MITSUYAMA and NAOKI ISHIGURO.
- Journal Title
  
  Nagoya J. Med. Sci.
  
  Volume: 75 Pages: 101-111
- NAID
  120005227637
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659672
[Journal Article] MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes2013
- Author(s)
  Matsukawa T, Sakai T, Yonezawa T, Hiraiwa H, Hamada T, Nakashima M, Ono Y, Ishizuka S, Nakahara H, Lotz MK, Asahara H, Ishiguro N.
- Journal Title
  
  Arthritis Research and Therapy
  
  Volume: 15(1)
- DOI
  10.1186/ar4164
- NAID
  40020134052
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24659672, KAKENHI-PROJECT-25830062
[Journal Article] Role of S100A12 in the pathogenesis of osteoarthritis.2012
- Author(s)
  Motoshige Nakashima
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 422 Pages: 508-14
- DOI
  10.1016/j.bbrc.2012.05.036
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659716, KAKENHI-PROJECT-24659672
[Journal Article] Inflammatory effect of advanced glycation end products on human meniscal cells from osteoarthritic knees cells2011
- Author(s)
  Hiraiwa H, Sakai T, Mitsuyama H, Hamada T, Yamamoto R, Omachi T, Ohno Y, Nakashima M, Ishiguro N
- Journal Title
  
  Inflammation Research
  
  Volume: 60(11) Pages: 1039-1048
- DOI
  10.1007/s00011-011-0365-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21390419, KAKENHI-PROJECT-22659269, KAKENHI-PROJECT-23659716
[Presentation] Activity of Wnt signaling in regenerated tendon and its effects on tendon repair.2020
- Author(s)
  Takefumi Sakaguchi, Bisei Ohkawara, Hideki Hiraiwa, Shinya Ishizuka, Kinji Ohno, Naoki Ishiguro
- Organizer
  ORS 2020 Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] 腱再生におけるwntシグナル活性の変化とそれが腱修復に与える影響2019
- Author(s)
  坂口健史,大河原美静, 岸本烈純, 宮本健太郎, 平岩秀樹, 石黒直樹, 大野欽司
- Organizer
  第34 回日本整形外科学会基礎学術集会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] Meclozine enhances skeletal muscle growth and improves exercise performance.2019
- Author(s)
  Yusuke Kawamura, Bisei Ohkawara, Hideki Hiraiwa, Shinya Ishizuka, Kinji Ohno, Naoki Ishiguro
- Organizer
  第5回日本筋学会学術集会
- Data Source
  KAKENHI-PROJECT-19H03779
[Presentation] Analysis of Tendon-related Genes and Angiogenesis-related Genes in Tendon-like Cells2017
- Author(s)
  Saho Tsuchiya, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Yohei Ono, Tomoyuki Oda, Satoshi Yamashita Kentaro Miyamoto, Yasuzumi Kishimoto, Yusuke Kawamura, Hiroki Oba, Naoki Ishiguro
- Organizer
  2017 Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15661
[Presentation] Wnt/β・カテニンシグナル経路は腱関連遺伝子発見に影響を与える2017
- Author(s)
  岸本烈純，大河原美静，酒井忠博，平岩秀樹，濱田恭，大野洋平，山下暁士，小田智之，土谷早穂，大野欽司，石黒直樹
- Organizer
  第90回日本整形外科学会学術総会
- Data Source
  KAKENHI-PROJECT-16K15661
[Presentation] Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling2017
- Author(s)
  Kentaro Miyamoto,Bisei Ohkawara,Akihiro Hirakawa,Tadahiro Sakai,Hideki Hiraiwa,Takashi Hamada,Kinji Ohno,Naoki Ishiguro
- Organizer
  2017 Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  サンディエゴ（アメリカ）
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15661
[Presentation] 変形性関節症由来軟骨細胞の再分化能についての検討2013
- Author(s)
  小田智之、酒井忠博、平岩秀樹、濱田恭、大野洋平、中島基成、石塚真哉、高松晃、山下暁士、石黒直樹
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Successful Phenotype Rescue of Monolayer-expanded Osteoarthritic Human Chondrocytes using Pellet Culture2013
- Author(s)
  Yohei Ono,Tadahiro Sakai, Hedeki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Shinya Ishizuka, Warren Knudson, Cheryl B. Knudson, Naoki Ishiguro
- Organizer
  2013 Annual meeting of AAOS
- Place of Presentation
  シカゴ（アメリカ）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Wntシグナル経路の制御を介した変形性関節症に対する新たな治療薬の検索2013
- Author(s)
  高松晃、酒井忠博、平岩秀樹、濱田恭、中島基成、松川哲也、小田智之、山下暁士、宮本健太郎、石黒直樹、大河原美静、大野欽司
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Drug screening for inhibition of Wnt/β-catenin signaling in osteoarthritis2013
- Author(s)
  Akira Takamatsu, Bisei Ohkawara, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Shinya Ishizuka, Tomoyuki Oda, Satoshi Yamashita, Kinji Ohno, Naoki Ishiguro
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] 変形性関節症由来軟骨細胞(OAC)の再分化能についての検討2013
- Author(s)
  小田智之、酒井忠博、平岩秀樹、濱田恭、大野洋平、中島基成、石塚真哉、高松晃、山下暁士、石黒直樹
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  千里ライフサイエンスセンター（豊中市）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] MicroRNA-23b suppress MMP-13 expression via post-transcriptional silencing of both hypoxia inducible factor-2α and rund-related transcription factor 2 expression in osteoarthritic chondrocytes2013
- Author(s)
  Ishizuka,S; Sakai, T; Hiraiwa, H; Hamada, T; Nakashima, M; Oda T; Takamatsu A; Yamashita S; Ishiguro, N
- Organizer
  2012 Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  San Antonio（アメリカ）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] 変形性関節症由来軟骨細胞(OAC)の再分化能についての検討2013
- Author(s)
  小田智之、酒井忠博、平岩秀樹、濱田恭、大野洋平、中島基成、石塚真哉、高松晃、山下暁士、石黒直樹
- Organizer
  第26回日本軟骨代謝学会
- Place of Presentation
  千里ライフサイエンスセンター(豊中市)
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] 変形性関節症由来軟骨細胞の再分化能についての検討2013
- Author(s)
  小田智之、酒井忠博、平岩秀樹、濱田恭、大野洋平、中島基成、石塚真哉、高松晃、山下暁士、石黒直樹
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ(千葉市)
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Drug screening for inhibition of Wnt/b-catenin signaling in osteoarthritis2013
- Author(s)
  Akira Takamatsu, Bisei Ohkawara, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Shinya Ishizuka, Tomoyuki Oda, Satoshi Yamashita, Kinji Ohno, Naoki Ishiguro
- Organizer
  2012 Annual Meeting of Orthopaedic Research Society
- Place of Presentation
  San Antonio（アメリカ）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] MicroRNA-23b suppress MMP-13 expression via post-transcriptional silencing of both hypoxia inducible factor-2αand rund-related transcription factor 2 expression in osteoarthritic chondrocytes2013
- Author(s)
  Shinya Ishizuka, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Tomoyuki Oda, Satoshi Yamashita, Akira Takamatsu, Naoki Ishiguro
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  San Antonio, USA
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Wntシグナル経路の制御を介した変形性関節症に対する新たな治療薬の検索2013
- Author(s)
  高松晃、酒井忠博、平岩秀樹、濱田恭、中島基成、松川哲也、小田智之、山下暁士、宮本健太郎、石黒直樹、大河原美静、大野欽司
- Organizer
  第28回日本整形外科学会基礎学術集会
- Place of Presentation
  幕張メッセ（千葉市）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Increased expression of Hypoxia-inducible factor-2α in osteoarthritic meniscus cells2012
- Author(s)
  Ishizuka,S; Sakai, T; Hiraiwa, H; Hamada, T;Nakashima, M; Oda T; Takamatsu A; YamashitaS; Ishiguro, N
- Organizer
  第40回日本関節病学会
- Place of Presentation
  鹿児島市民文化ホール、鹿児島サンロイヤルホテル（鹿児島
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] microRNA-23bはHIF2-α、RUNX2の発現抑制を介してOA軟骨細胞におけるMMP-13の発現を制御する2012
- Author(s)
  石塚真哉、酒井忠博、平岩秀樹、濱田恭、中島基茂、小田智之、高松晃、山下暁士、石黒直樹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場(名古屋市)
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] The effect of S100A12 in the pathogenesis of osteoarthritis2012
- Author(s)
  Nakashima M, Sakai T, Hiraiwa H, Hamada T, Ishiguro N, et al
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  San Francisco, California, USA
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] 他人OA軟骨細胞におけるmicroRNA-125bによるAggrecanase-1(ADAMTS4)の発現制御2012
- Author(s)
  松川哲也、酒井忠博、平岩秀樹、濱田恭、大間知孝顕、中島基茂
- Organizer
  第25回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-22659271
[Presentation] S100A12タンパクによる変形性関節症の進行における影響2012
- Author(s)
  中島基成、酒井忠博、平岩秀樹、濱田恭、石塚真哉、小田智之、高松晃、山下暁士、石黒直樹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] S100A12タンパクによる変形性関節症の進行における影響2012
- Author(s)
  中島基成、酒井忠博、平岩秀樹、濱田恭、石塚真哉、小田智之、高松晃、山下暁士、石黒直樹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] Increased expression of Hypoxia-inducible factor-2α in osteoarthritic meniscus cells2012
- Author(s)
  Ishizuka,S; Sakai, T; Hiraiwa, H; Hamada, T; Nakashima, M; Oda T; Takamatsu A; Yamashita S; Ishiguro, N
- Organizer
  第40回日本関節病学会
- Place of Presentation
  鹿児島市民文化ホール、鹿児島サンロイヤルホテル（鹿児島市）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] OA半月板におけるHIF-2αの高発現2012
- Author(s)
  石塚真哉, 酒井忠博, 平岩秀樹, 濱田恭ら
- Organizer
  第40回日本関節病学会
- Place of Presentation
  鹿児島
- Year and Date
  2012-11-08
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] 変形性関節症(OA)半月板細胞におけるhypoxiainducible factor-2α(HIF-2α)の高発現と軟骨内骨化関連遺伝子の制御2012
- Author(s)
  石塚真哉, 酒井忠博, 平岩秀樹, 濱田恭ら
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] microRNA-23bはHIF2-α、RUNX2の発現抑制を介してOA軟骨細胞におけるMMP-13の発現を制御する。2012
- Author(s)
  石塚真哉、酒井忠博、平岩秀樹、濱田恭、中島基成、小田智之、高松晃、山下暁士、石黒直樹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] OA半月板におけるHypoxia-inducible factor-2α の高発現2012
- Author(s)
  石塚真哉、酒井忠博、平岩秀樹、濱田恭、中島基成、小田智之、高松晃、山下暁士、石黒直樹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] 変形性関節症(OA)半月板細胞におけるhypoxiainducible factor-2α(HIF-2α)の高発現と軟骨内骨化関連遺伝子の制御2012
- Author(s)
  石塚真哉、酒井忠博、平岩秀樹、濱田恭、中島基成、小田智之、高松晃、山下暁士、石黒直樹
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋国際会議場（名古屋市熱田区）
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] MicroRNA-125b Regulates the Expression of Aggrecanase-1 (ADAMTS4) in Human Osteoarthritic Chondrocytes2012
- Author(s)
  Tetsuya Matsukawa, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Takaaki Omachi, Motoshige Nakashima, Shinya Ishizuka, Tomoyuki Oda, Akira Takamatsu, Satoshi Yamashita, Naoki Ishiguro
- Organizer
  10th World Congress of the International Cartilage Repair Society　2012
- Place of Presentation
  モントリオール（カナダ）
- Data Source
  KAKENHI-PROJECT-24659672
[Presentation] Increased expression of Hypoxia-inducible factor-2alfa in osteoarthritic meniscus cells2012
- Author(s)
  Ishizuka S, Sakai T, Hiraiwa H, Hamada T, Ishiguro N, et al
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  San Francisco, California, USA
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] S100A12タンパクによる変形性関節症の進行における影響2012
- Author(s)
  中島基成, 酒井忠博, 平岩秀樹, 濱田恭ら
- Organizer
  第27回日本整形外科学会基礎学術集会
- Place of Presentation
  名古屋
- Year and Date
  2012-10-26
- Data Source
  KAKENHI-PROJECT-23659716
[Presentation] MicroRNA-23b and 27b regulate both Hypoxia-inducible factor-2a and endochondral ossification related gene expressions in osteoarthritic chondrocytes2012
- Author(s)
  Shinya Ishizuka, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Takaaki Ohmachi, Yohei Ohno, Motoshige Nakashima, Tetsuya Matsukawa, et al.
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  Spotlight Session
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-22659271
[Presentation] MicroRNA-125b regulates the expression of Aggrecanase-1(ADAMTS4) in human osteoarthritic chondrocytes2012
- Author(s)
  Tetsuya Matsukawa, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Takaaki Ohmachi, Yohei Ohno, Motoshige Nakashima, Shinya Ishizuka, et al.
- Organizer
  Orthopaedic Research Society
- Place of Presentation
  Spotlight Session
- Year and Date
  2012-02-04
- Data Source
  KAKENHI-PROJECT-22659271
[Presentation] 他microRNA-23b, 27bはOAの軟骨細胞においてHypoxia-inducible factor-2a(HIF-2a)及び軟骨内骨化関連遺伝子の発現を制御する2012
- Author(s)
  石塚真哉、酒井忠博、平岩秀樹、濱田恭、大間知孝顕、中島基茂
- Organizer
  第25回日本軟骨代謝学会
- Data Source
  KAKENHI-PROJECT-22659271
[Presentation] 膝蓋靭帯欠損部再生組織における腱関連遺伝子と軟骨関連遺伝子の発現2011
- Author(s)
  大間知孝顕、酒井忠博、平岩秀樹、濱田恭、山本隆一郎、中島基成、大野洋平、犬飼規夫、松川哲也、石塚真哉、石黒直樹
- Organizer
  第24回日本軟骨代謝学会
- Place of Presentation
  九州大学百年講堂(福岡市)
- Year and Date
  2011-03-04
- Data Source
  KAKENHI-PROJECT-22659271
[Presentation] 単層培養過程の継代に伴うヒトOA軟骨細胞の表現型変化と再分化能2011
- Author(s)
  大野洋平、酒井忠博、平岩秀樹、濱田恭、山本隆一郎、大間知孝顕、中島基成、犬飼規夫、石塚真哉、松川哲也、石黒直樹
- Organizer
  第24回日本軟骨代謝学会
- Place of Presentation
  九州大学百年講堂(福岡市)
- Year and Date
  2011-03-05
- Data Source
  KAKENHI-PROJECT-22659271

1. SAKAI Tadahiro (60378198)

# of Collaborated Projects: 6 results

# of Collaborated Products: 47 results
2. HAMADA Takashi (90566978)

# of Collaborated Projects: 4 results

# of Collaborated Products: 37 results
3. YAMAMOTO Ryuichiro (80586743)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. Ishiguro Naoki (20212871)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. 高橋伸典 (20570196)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
6. Ota Susumu (50452199)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 光山浩人 (80467282)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 宮本健太郎 (50789899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 大野洋平 (60792736)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 長谷和徳 (10357775)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 坂井建宣 (10516222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 伊東保志 (70268069)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 福山篤司 (40452198)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 後藤基志 (00290916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 大古拓史 (60715126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 長谷川幸治 (50208500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 今釜史郎 (40467288)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 八田武志 (80030469)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 水野正明 (70283439)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 大野欽司 (80397455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
21. 大河原美静 (80589606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
22. OHMACHI Takaaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. YONEZAWA Tomo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HIRAIWA Hideki 平岩 秀樹

平岩 秀樹 ヒライワ ヒデキ

Research Projects

Research Products

Co-Researchers

Ｗｎｔ/βカテニン・ＡＤＡＭ１０阻害による新規作用機序の変性関節症治療薬の開発Ongoing

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

Diagnosis of Motor function and improvement methods of motor function of community living elderly people using artificial intelligenceOngoing

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

変形性関節症における軟骨細胞の再プログラミングによる多分化能の獲得

Principal Investigator

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Research Institution

Development of a new drug for treating osteoarthritis caused by increased expression of Dkk1 molecule

Principal Investigator

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Research Institution

Establishment of a checkup method for early knee osteoarthritis using analyses of vibroarthrography from the knee joint

Principal Investigator

Project Period (FY)

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Research Institution

Micro RNAs could modulate the reprogramming of osteoarthritic chondrocytes.

Principal Investigator

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The effect of advanced glycation end products to meniscal degeneration of osteoarthritic kneesPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The pathological roles of micro RNAs in osteoarthritis

Principal Investigator

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Research Institution

[Journal Article] Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 小児膝伸展機構損傷後に膝蓋腱骨化を生じた２例2017

Author(s)

Journal Title

Data Source

[Journal Article] スポーツで受傷した膝複合靱帯損傷に総腓骨神経損傷を合併した２例2017

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Journal Title

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[Journal Article] Coxitis kneeに対する人工膝関節置換術の治療成績2017

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[Journal Article] 反復性肩関節脱臼に対する空気を用いた関節造影CTの診断能の検討2017

Author(s)

Journal Title

NAID

Data Source

[Journal Article] Hypoxia-inducible factor-2α induces expression of type X collagen and matrix metalloproteinases 13 in osteoarthritic meniscal cells2016

Author(s)

Journal Title

DOI

Data Source

HIRAIWA Hideki 平岩秀樹

平岩秀樹ヒライワヒデキ