MIZUSHIGE TAKAFUMI 水重貴文

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MIZUSHIGE Takafumi 水重貴文

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Researcher Number	70571008
Other IDs
Affiliation (Current)	2025: 宇都宮大学, 農学部, 准教授
Affiliation (based on the past Project Information) *help	2023 – 2024: 宇都宮大学, 農学部, 准教授 2013 – 2021: 宇都宮大学, 農学部, 准教授 2012: 京都大学, 学際融合教育研究推進センター・生理化学研究ユニット, 助教
Review Section/Research Field	Principal Investigator Food science / Basic Section 08030:Family and consumer sciences, and culture and living-related / Basic Section 38050:Food sciences-related
Keywords	Principal Investigator 海馬 / ストレス / ペプチド / 神経新生 / 精神的ストレス / マウス / うつ / 体内動態 / ジペプチド / 不安 … More / ドーパミン / 行動 / 認知機能 / うつ様行動 / コラーゲンペプチド / コラーゲン / 腸管吸収 / 消化吸収 / 神経幹細胞 / 骨形成タンパク質 / 骨形成タンパク質受容体 / セロトニン / 抗不安作用 / 抗うつ作用 / チロシルロイシン / 受容体同定 / 構造活性相関 / 気分障害 / 低分子ペプチド Less

Effects of food peptide on cognitive function and the hippocampal mechanismPrincipal Investigator
- Principal Investigator
  
  水重貴文
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Utsunomiya University
Mechanism of neuromodulatory effects by collagen peptidesPrincipal Investigator
- Principal Investigator
  
  Mizushige Takafumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Utsunomiya University
Gastrointestinal absorption mechanism and novel physiological function of food-derived low-molecular weight peptidesPrincipal Investigator
- Principal Investigator
  
  Mizushige Takafumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Utsunomiya University
Novel signaling pathway in food-derived neuromodulating peptidesPrincipal Investigator
- Principal Investigator
  
  Mizushige Takafumi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Utsunomiya University
Identification of target molecule on novel functional peptides in the central nervous systemPrincipal Investigator
- Principal Investigator
  
  MIZUSHIGE Takafumi
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Food science
- Research Institution
  Utsunomiya University
  Kyoto University

All 2024 2023 2022 2021 2020 2019 2018 2017 2015 2014 2013 2012

All Journal Article Presentation Patent

[Journal Article] Dietary Alaska Pollack Protein Induces Acute Skeletal Muscle Hypertrophy in Rats, Regardless of Specific Amino Acid and Amino Acid Balance of Diet2023
- Author(s)
  Uchida Kenji、Fujitani Mina、Mizushige Takafumi、Hayamizu Kohsuke、Hara Yuma、Sawai Mariko、Utsunomiya Sachi、Uehigashi Ryota、Okada Shinji、Kishida Taro
- Journal Title
  
  Nutraceuticals
  
  Volume: 3 Issue: 4 Pages: 513-528
- DOI
  10.3390/nutraceuticals3040037
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K25604
[Journal Article] Dietary Alaska Pollack Protein Induces Acute and Sustainable Skeletal Muscle Hypertrophy in Rats.2022
- Author(s)
  Uchida K, Fujitani M, Mizushige T, Kawabata F, Hayamizu K, Uozumi K, Hara Y, Sawai M, Uehigashi R, Okada S, Goto-Inoue N, Morisasa M, Kishida T.
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 3 Pages: 547-547
- DOI
  10.3390/nu14030547
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927, KAKENHI-PROJECT-21H00803
[Journal Article] Mechanism of Soy Isoflavone Daidzein-Induced Female-Specific Anorectic Effect.2022
- Author(s)
  Fujitani M, Mizushige T, Adhikari S, Bhattarai K, Kishida T.
- Journal Title
  
  Metabolites
  
  Volume: 12 Issue: 3 Pages: 252-252
- DOI
  10.3390/metabo12030252
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927, KAKENHI-PROJECT-21K14805
[Journal Article] Lipid Dynamics due to Muscle Atrophy Induced by Immobilization2021
- Author(s)
  Kimura K, Morisasa M, Mizushige T, Karasawa R, Kanamaru C, Kabuyama Y, Hayasaka T, Mori T, Goto-Inoue N.
- Journal Title
  
  J. Oleo Sci.
  
  Volume: 70 Issue: 7 Pages: 937-946
- DOI
  10.5650/jos.ess21045
- NAID
  130008060027
- ISSN
  1345-8957, 1347-3352
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K05927, KAKENHI-PROJECT-23K21605
[Journal Article] Neuromodulatory peptides: Orally active anxiolytic-like and antidepressant-like peptides derived from dietary plant proteins2021
- Author(s)
  Mizushige T
- Journal Title
  
  Peptides
  
  Volume: 142 Pages: 170569-170569
- DOI
  10.1016/j.peptides.2021.170569
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927
[Journal Article] Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice.2020
- Author(s)
  Mizushige T, Uchida T, Ohinata K.
- Journal Title
  
  Sci Rep
  
  Volume: 10 Issue: 1 Pages: 2257-2257
- DOI
  10.1038/s41598-020-59039-7
- NAID
  120006879492
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927
[Journal Article] Prolyl-hydroxyproline, a collagen-derived dipeptide, enhances hippocampal cell proliferation, which leads to antidepressant-like effects in mice.2020
- Author(s)
  Nogimura D, Mizushige T, Taga Y, Nagai A, Shoji S, Azuma N, Kusubata M, Adachi SI, Yoshizawa F, Kabuyama Y.
- Journal Title
  
  FASEB J
  
  Volume: 34 Issue: 4 Pages: 5715-5723
- DOI
  10.1096/fj.201902871r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927
[Journal Article] Orally administered milk-derived tripeptide improved cognitive decline in mice fed a high-fat diet.2019
- Author(s)
  Nagai A, Mizushige T, Matsumura S, Inoue K, Ohinata K.
- Journal Title
  
  FASEB J
  
  Volume: 33 Issue: 12 Pages: 14095-14102
- DOI
  10.1096/fj.201900621r
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927, KAKENHI-PROJECT-18K19737
[Journal Article] Ginger-Degraded Collagen Hydrolysate Exhibits Antidepressant Activity in Mice2019
- Author(s)
  Mizushige T, Nogimura D, Nagai A, Mitsuhashi H, Taga Y, Kusubata M, Hattori S, Kabuyama Y.
- Journal Title
  
  Journal of Nutritional Science and Vitaminology
  
  Volume: 65 Issue: 3 Pages: 251-257
- DOI
  10.3177/jnsv.65.251
- NAID
  130007670177
- ISSN
  0301-4800, 1881-7742
- Year and Date
  2019-06-30
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K05927
[Journal Article] Absorption and metabolism of orally administered collagen hydrolysates evaluated by the vascularly perfused rat intestine and liver in situ 2018
- Author(s)
 Osawa Y, Mizushige T, Jinno S, Sugihara F, Inoue N, Tanaka H, Kabuyama Y.
- Journal Title
 
 Biomed. Res.
 
 Volume: 39 Issue: 1 Pages: 1-11
- DOI
 10.2220/biomedres.39.1
- NAID
 130006394276
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K07731
[Journal Article] Enzymatic digest of whey protein and wheylin-1, a dipeptide released in the digest, increase insulin sensitivity in an Akt phosphorylation-dependent manner.2018
- Author(s)
  Ogiwara M, Ota W, Mizushige T, Kanamoto R, Ohinata K.
- Journal Title
  
  Food Funct.
  
  Volume: 9 Issue: 9 Pages: 4635-4641
- DOI
  10.1039/c8fo00919h
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K07731
[Journal Article] Fish protein hydrolysate exhibits anti-obesity activity and reduces hypothalamic neuropeptide Y and agouti-related protein mRNA expressions in rats 2017
- Author(s)
 Mizushige T, Komiya M, Onda M, Uchida K, Hayamizu K, Kabuyama Y.
- Journal Title
 
 Biomed. Res.
 
 Volume: 38 Issue: 6 Pages: 351-357
- DOI
 10.2220/biomedres.38.351
- NAID
 130006248351
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-16K07731
[Journal Article] A novel Alaska pollack-derived peptide, which increases glucose uptake in skeletal muscle cells, lowers the blood glucose level in diabetic mice2015
- Author(s)
  Ayabe T, Mizushige T, Ota W, Kawabata F, Hayamizu K, Han L, Tsuji T, Kanamoto R, Ohinata K
- Journal Title
  
  Food & Function
  
  Volume: 6 Issue: 8 Pages: 2749-2757
- DOI
  10.1039/c5fo00401b
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26850081
[Journal Article] Fish protein intake induces fast-muscle hypertrophy and reduces liver lipids and serum glucose levels in rats2015
- Author(s)
  Kawabata F, Mizushige T, Uozumi K, Hayamizu K, Li H, Tsuji T, Kishida T.
- Journal Title
  
  Bioscience Biotechnology and Biochemistry
  
  Volume: 79 Issue: 1 Pages: 109-116
- DOI
  10.1080/09168451.2014.951025
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26850081
[Journal Article] Antidepressant-like effect of food-derived pyroglutamyl peptides in mice2015
- Author(s)
  Yamamoto Y, Mizushige T, Mori Y, Shimmura Y, Fukutomi Y, Kanamoto R, Ohinata K
- Journal Title
  
  Neuropeptides
  
  Volume: 51 Pages: 25-29
- DOI
  10.1016/j.npep.2015.04.002
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26850081, KAKENHI-PROJECT-26292070
[Journal Article] Identification of novelβ-lactoglobulin-derived peptides, wheylin-1 and -2, having anxiolytic-like activity in mice2014
- Author(s)
  Yamada A, Mizushige T, Kanamoto R, Ohinata K
- Journal Title
  
  Mol Nutr Food Res
  
  Volume: 58(2) Pages: 353-8
- Data Source
  KAKENHI-PROJECT-24780127
[Journal Article] Identification of novel β-lactoglobulin-derived peptides, wheylin-1 and -2, having anxiolytic-like activity in mice.2014
- Author(s)
  Yamada A, Mizushige T, Kanamoto R, Ohinata K.
- Journal Title
  
  Mol Nutr Food Res.
  
  Volume: 58(2) Issue: 2 Pages: 353-8
- DOI
  10.1002/mnfr.201300237
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380076, KAKENHI-PROJECT-24780127
[Journal Article] Orally administered δ opioid agonist peptide rubiscolin-6 stimulates food intake in aged mice with ghrelin resistance.2014
- Author(s)
  Miyazaki Y, Kaneko K, Iguchi S, Mizushige T, Kanamoto R, Yoshikawa M, Shimizu T, Ohinata K.
- Journal Title
  
  Mol Nutr Food Res
  
  Volume: 58 Issue: 10 Pages: 2046-2052
- DOI
  10.1002/mnfr.201400100
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26292070, KAKENHI-PROJECT-26850081
[Journal Article] δ-Opioid receptor activation stimulates normal diet intake but conversely suppresses high-fat diet intake in mice.2014
- Author(s)
  Kaneko K, Mizushige T, Miyazaki Y, Lazarus M, Urade Y, Yoshikawa M, Kanamoto R, Ohinata K.
- Journal Title
  
  Am J Physiol Regul Integr Comp Physiol.
  
  Volume: 306(4) Issue: 4 Pages: 265-272
- DOI
  10.1152/ajpregu.00405.2013
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23380076, KAKENHI-PROJECT-24300129, KAKENHI-PROJECT-24780127
[Journal Article] Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice.2013
- Author(s)
  Mizushige T, Kanegawa N, Yamada A, Ota A, Kanamoto R, Ohinata K.
- Journal Title
  
  Neurosci Lett.
  
  Volume: 543 Pages: 126-9
- DOI
  10.1016/j.neulet.2013.03.043
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380076, KAKENHI-PROJECT-24780127
[Journal Article] Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice2013
- Author(s)
  Mizushige T, Kanegawa N, Yamada A, Ota A, Kanamoto R, Ohinata K
- Journal Title
  
  Neurosci Lett
  
  Volume: 24;543 Pages: 126-9
- Data Source
  KAKENHI-PROJECT-24780127
[Journal Article] Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine αS-casein.2013
- Author(s)
  Mizushige T, Sawashi Y, Yamada A, Kanamoto R, Ohinata K.
- Journal Title
  
  FASEB J.
  
  Volume: 00
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24780127
[Journal Article] Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovineαS-casein2013
- Author(s)
  Mizushige T, Sawashi Y, Yamada A, Kanamoto R, Ohinata K
- Journal Title
  
  FASEB J
  
  Volume: 27(7) Pages: 2911-7
- Data Source
  KAKENHI-PROJECT-24780127
[Journal Article] Complement C5a exhibits anxiolytic-like activity via the prostaglandin D2-DP1 receptor system coupled to adenosine A2A and GABAA receptors2012
- Author(s)
  Miyamoto C, Yoshida M, Yoshikawa M, Mizushige T, Ohinata K
- Journal Title
  
  Prostaglandins Other Lipid Media
  
  Volume: 98(1-2) Pages: 17-22
- Data Source
  KAKENHI-PROJECT-24780127
[Journal Article] Characterization of ovolin, an orally active tryptic peptide released from ovalbumin with anxiolytic-like activity2012
- Author(s)
  Oda A, Kaneko K, Mizushige T, Lazarus M, Urade Y, Ohinata K
- Journal Title
  
  J Neurochem
  
  Volume: 122(2) Pages: 356-62
- Data Source
  KAKENHI-PROJECT-24780127
[Patent] ソバ由来成分を含有する抗うつ性組成物2020
- Inventor(s)
  田村由自、水重貴文、佐藤史佳、金野尚武、羽生直人、他２名
- Industrial Property Rights Holder
  田村由自、水重貴文、佐藤史佳、金野尚武、羽生直人、他２名
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2020-065799
- Filing Date
  2020
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] コラーゲンペプチドの脳神経調節作用2024
- Author(s)
  水重貴文、蕪山由己人
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-23K25604
[Presentation] そばプロラミンは腸内細菌叢の変化に伴い抗うつ様効果を有する2023
- Author(s)
  兼子歩乃圭、水重貴文、茗花美幸、金野尚武、前田勇、羽生直人、蕪山由己人
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-23K25604
[Presentation] コラーゲンペプチドは海馬インスリンシグナルを活性化し認知機能を改善する2023
- Author(s)
  大濵直輝、水重貴文、橋本颯太、多賀祐喜、楠畑雅、蕪山由己人
- Organizer
  日本アミノ酸学会第17回学術大会
- Data Source
  KAKENHI-PROJECT-23K25604
[Presentation] そばタンパク質の抗うつ作用と腸脳相関の関与2022
- Author(s)
  佐藤史佳，水重貴文，茗花美幸，金野尚武，前田勇，羽生直人，蕪山由己人
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] ゆずの調合香料が精神的ストレスに及ぼす影響2021
- Author(s)
  植松大成, 水重貴文, 北本拓磨, 謝肖男, 佐藤翔, 山崎裕輝, 松下翔, 鶴田真理子, 長谷川光司, 蕪山由己人
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 不運動・軽運動モデルに対する魚肉タンパク質の効果の検証2021
- Author(s)
  森笹瑞季、木村圭佑、水重貴文、蕪山由己人、内田健志、吉田恵里子、森司、井上菜穂子
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 関節固定による筋萎縮時の脂質代謝動態2021
- Author(s)
  木村圭佑、森笹瑞季、水重貴文、蕪山由己人、早坂孝宏、吉田恵里子、内田健志、森司、井上菜穂子
- Organizer
  日本農芸化学会2021年度大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] ステロール類縁物質である大豆イソフラボンの生理作用―食欲抑制効果を中心に―2021
- Author(s)
  岸田太郎, 藤谷美菜, 水重貴文
- Organizer
  第75回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] コラーゲンペプチドの血液脳関門透過と神経軸索伸長への影響2021
- Author(s)
  高橋佳菜, 水重貴文, 多賀祐喜, 楠畑雅, 蕪山由己人
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] ジヒドロキシプロリン含有ペプチドの有機合成とその生理活性について2020
- Author(s)
  堀優希、二瓶賢一、水重貴文、蕪山由己人
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 環状ペプチドを含むコラーゲン加水分解物の皮膚光老化に対する影響解析2020
- Author(s)
  阿久津歩夢, 篠原日菜子, 多賀祐喜, 楠畑雅, 水重貴文, 蕪山由己人
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 社会的敗北ストレスモデルにおけるコラーゲン分解物の抗うつ作用と神経炎症への影響2020
- Author(s)
  野木村大、水重貴文、多賀祐喜、楠畑雅、蕪山由己人
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] メラノーマ皮膚癌細胞の増殖に対するアミノ酸栄養及び温度の影響評価2020
- Author(s)
  小石川眞紀, 三浦亮太郎, 水重貴文, 蕪山由己人
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] そば摂取がうつ様行動に及ぼす影響とそのメカニズム解析2020
- Author(s)
  佐藤史佳, 水重貴文, 田村由自, 野木村大, 金野尚武, 吉澤史昭, 前田勇, 羽生直人, 蕪山由己人
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] コラーゲン分解物は社会的敗北ストレスにより誘導される神経炎症を抑制する2020
- Author(s)
  野木村大, 水重貴文, 多賀祐喜, 楠畑雅, 吉澤史昭, 蕪山由己人
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] そばタンパク質の抗うつ作用とそのメカニズム2020
- Author(s)
  佐藤史佳、水重貴文、田村由自、茗花美幸、金野尚武、前田勇、羽生直人、蕪山由己人
- Organizer
  日本アミノ酸学会第14回学術大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 食品由来ペプチドの脳神経調節作用に関する研究2020
- Author(s)
  水重貴文
- Organizer
  第74回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] コラーゲン由来ペプチドの脳内移行2020
- Author(s)
  高橋佳菜、水重貴文、多賀祐喜、楠畑雅、蕪山由己人
- Organizer
  日本アミノ酸学会第14回学術大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 熱処理コラーゲン分解物由来ペプチドの体内動態および認知機能向上作用2020
- Author(s)
  飯塚真理乃、水重貴文、多賀祐喜、楠畑雅、蕪山由己人
- Organizer
  日本アミノ酸学会第14回学術大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 廃用性筋委縮の回復時においてスケソウダラ由来タンパク質配合餌の摂取が骨格筋肥大に与える影響の解析2020
- Author(s)
  木村圭佑, 森笹瑞季, 水重貴文, 蕪山由己人, 唐澤陸央, 金丸千夏, 内田健志, 吉田恵里子, 森司, 井上菜穂子
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] コラーゲン分解物の認知機能向上作用とその活性成分の同定2019
- Author(s)
  飯塚真理乃, 野木村大, 多賀祐喜, 岩井ミチ, 楠畑雅, 水重貴文, 蕪山由己人
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 魚肉タンパク質摂取の廃用性筋萎縮の回復に対する影響2019
- Author(s)
  唐澤陸央, 金丸千夏, 木村圭佑, 森笹瑞季, 内田健志, 吉田恵里子, 井上菜穂子, 森司, 水重貴文, 蕪山由己人
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 鮒ずし由来乳酸菌FS-1株の免疫賦活による感染症予防効果2019
- Author(s)
  篠原日菜子、阿久津歩夢、吉田恵里子、内田健志、韓力、水重貴文、蕪山由己人
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲン由来ペプチドの投与がマウスの皮膚創傷治癒に与える影響の解析2019
- Author(s)
  佐藤侑紀、須永真実、水重貴文、蕪山由己人
- Organizer
  日本農芸化学会2019年度大会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲン分解物が海馬モノアミン代謝に及ぼす影響2019
- Author(s)
  野木村大, 多賀祐喜, 楠畑雅, 安達真一, 吉澤史昭, 水重貴文, 蕪山由己人
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 高脂肪食摂取による認知機能低下に対する牛乳由来ペプチドの改善機構2019
- Author(s)
  古川太一, 永井研迅, 水重貴文, 松村成暢, 井上和生, 大日向耕作
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-19K05927
[Presentation] 高脂肪食摂取による認知機能低下に対する牛乳由来ペプチドの改善作用2018
- Author(s)
  永井研迅，水重貴文，松村成暢，井上和生，大日向耕作
- Organizer
  日本アミノ酸学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲン由来ペプチドが培養海馬神経幹細胞の増殖に及ぼす影響2018
- Author(s)
  庄司紗代，水重貴文，蕪山由己人
- Organizer
  日本アミノ酸学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] ジヒドロキシプロリン含有ペプチドの抗酸化特性の評価2018
- Author(s)
  堀優希，二瓶泰雅，鈴木稔朗，三井美彩，三田千鶴，水重貴文，二瓶賢一，蕪山由己人
- Organizer
  日本アミノ酸学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コルチコステロン投与マウスにおけるコラーゲン分解物の抗うつ作用とその作用に対するドーパミン神経の関与2018
- Author(s)
  野木村大，三ツ橋春香，多賀祐喜，楠畑雅，服部俊治，水重貴文，蕪山由己人
- Organizer
  日本アミノ酸学会第12回学術大会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲンペプチドPro-Hypの抗うつ作用2017
- Author(s)
  永井研迅、東奈央、水重貴文、蕪山由己人
- Organizer
  日本栄養食糧学会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲン由来抗うつペプチドの同定およびその脳脊髄液への移行2017
- Author(s)
  永井研迅、東奈央、水重貴文、蕪山由己人
- Organizer
  日本農芸化学会関東支部
- Invited
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] 海馬における神経幹細胞の増殖および神経栄養因子の発現に及ぼすコラーゲン加水分解物の影響2017
- Author(s)
  野木村大、永井研迅、多賀祐喜、楠畑雅、林田治、服部俊治、水重貴文、蕪山由己人
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲン由来抗うつペプチドの同定およびその脳脊髄液への移行2017
- Author(s)
  永井研迅、東奈央、水重貴文、蕪山由己人
- Organizer
  日本農芸化学会2017年度大会
- Place of Presentation
  京都女子大学
- Year and Date
  2017-03-19
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] コラーゲン加水分解物投与がマウス皮膚幹細胞に対して与える影響の解析2017
- Author(s)
  森傑、上原ほのか、水重貴文、蕪山由己人
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-16K07731
[Presentation] 海馬神経新生を誘導する抗うつジペプチドTyr-Leuの標的受容体同定2014
- Author(s)
  水重貴文、石田祐己、金本龍平、大日向耕作
- Organizer
  日本農芸化学会2014年度大会
- Place of Presentation
  東京
- Year and Date
  2014-03-30
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] Novel anxiolytic-like peptide released from alpha-s-casein by gastrointestinal proteases2013
- Author(s)
  Takafumi Mizushige, Yurina Sawashi, Ayako Yamada, Ryuhei Kanamoto, Kousaku Ohinata
- Organizer
  IUNS 20th International Congress of Nutrition
- Place of Presentation
  スペイン・グラナダ
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] ペプチドTyr-Leuの抗うつメカニズム―海馬神経新生に及ぼす影響―2013
- Author(s)
  水重貴文、山本裕佳子、澤祇有里菜、金本龍平、大日向耕作
- Organizer
  第67回日本栄養食糧学会
- Place of Presentation
  名古屋
- Year and Date
  2013-05-26
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] Novel anxiolytic-like peptide released from alpha-s-casein by gastrointestinal proteases2013
- Author(s)
  Takafumi Mizushige, Yurina Sawashi, Ayako Yamada, Ryuhei Kanamoto, Kousaku Ohinata
- Organizer
  IUNS 20th International Congress of Nutrition
- Place of Presentation
  Granada (Spain)
- Year and Date
  2013-09-20
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] 牛乳αs-caseinの消化管酵素分解により新しい抗不安トリペプチドTyr-Leu-Glyが生成する2013
- Author(s)
  水重　貴文、澤岻　有里菜、金本　龍平、大日向　耕作
- Organizer
  日本農芸化学会２０１３年度大会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] 牛乳αs-caseinから抗不安トリペプチドTyr-Leu-Glyが生成する2013
- Author(s)
  水重貴文、澤岻有里菜、金本龍平、大日向耕作
- Organizer
  日本農芸化学会2013年度大会
- Place of Presentation
  仙台
- Year and Date
  2013-03-28
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] ジペプチドTyr-Leuの抗うつメカニズム―海馬神経新生に及ぼす影響―2013
- Author(s)
  水重貴文、山本裕佳子、澤祇有里菜、金本龍平、大日向耕作
- Organizer
  第67回日本栄養食糧学会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] ジペプチドTyr-Leuは単回経口投与で抗うつ作用を示す2012
- Author(s)
  水重　貴文、大日向　耕作
- Organizer
  第３５回日本神経科学大会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] 牛乳α-casozepineとその分子内に存在するジペプチドTyr-Leuの抗不安機構の比較2012
- Author(s)
  水重貴文、大日向耕作
- Organizer
  第66回日本栄養食糧学会
- Place of Presentation
  仙台
- Year and Date
  2012-05-20
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] ジペプチドTyr-Leuは単回経口投与で抗うつ作用を示す2012
- Author(s)
  水重貴文、大日向耕作
- Organizer
  第35回日本神経科学会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] ジペプチドYLによる抗うつ作用2012
- Author(s)
  大日向耕作、水重貴文、金本龍平
- Organizer
  第６回日本アミノ酸学会
- Place of Presentation
  千葉
- Data Source
  KAKENHI-PROJECT-24780127
[Presentation] 牛乳α-casozepineとその分子内に存在するジペプチドTyr-Leuの抗不安機構の比較2012
- Author(s)
  水重　貴文、大日向　耕作
- Organizer
  第６６回日本栄養食糧学会
- Place of Presentation
  仙台
- Data Source
  KAKENHI-PROJECT-24780127

1. 蕪山由己人 (20285042)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. 鈴木智大 (10649601)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 高堂裕平 (60593564)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 大日向耕作

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. 裏出良博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIZUSHIGE TAKAFUMI 水重 貴文

MIZUSHIGE Takafumi 水重 貴文

Research Projects

Research Products

Co-Researchers

Effects of food peptide on cognitive function and the hippocampal mechanismPrincipal Investigator

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Mechanism of neuromodulatory effects by collagen peptidesPrincipal Investigator

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Gastrointestinal absorption mechanism and novel physiological function of food-derived low-molecular weight peptidesPrincipal Investigator

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Novel signaling pathway in food-derived neuromodulating peptidesPrincipal Investigator

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Identification of target molecule on novel functional peptides in the central nervous systemPrincipal Investigator

Principal Investigator

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[Journal Article] Dietary Alaska Pollack Protein Induces Acute Skeletal Muscle Hypertrophy in Rats, Regardless of Specific Amino Acid and Amino Acid Balance of Diet2023

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[Journal Article] Dietary Alaska Pollack Protein Induces Acute and Sustainable Skeletal Muscle Hypertrophy in Rats.2022

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[Journal Article] Mechanism of Soy Isoflavone Daidzein-Induced Female-Specific Anorectic Effect.2022

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[Journal Article] Lipid Dynamics due to Muscle Atrophy Induced by Immobilization2021

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[Journal Article] Neuromodulatory peptides: Orally active anxiolytic-like and antidepressant-like peptides derived from dietary plant proteins2021

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[Journal Article] Dipeptide tyrosyl-leucine exhibits antidepressant-like activity in mice.2020

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[Journal Article] Prolyl-hydroxyproline, a collagen-derived dipeptide, enhances hippocampal cell proliferation, which leads to antidepressant-like effects in mice.2020

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[Journal Article] Orally administered milk-derived tripeptide improved cognitive decline in mice fed a high-fat diet.2019

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[Journal Article] Ginger-Degraded Collagen Hydrolysate Exhibits Antidepressant Activity in Mice2019

MIZUSHIGE TAKAFUMI 水重貴文

MIZUSHIGE Takafumi 水重貴文