Tanaka Hiroki 田中宏樹

… Alternative Names

TANAKA Hiroki 田中宏樹

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Researcher Number	70596155
Other IDs
Affiliation (Current)	2025: 国立研究開発法人医薬基盤・健康・栄養研究所, 医薬基盤研究所難病・免疫ゲノム研究センター, 研究員 2025: 旭川医科大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 旭川医科大学, 医学部, 講師 2015 – 2022: 旭川医科大学, 医学部, 助教 2014 – 2015: 旭川医科大学, 医学部, 客員講師 2013 – 2014: 旭川医科大学, 医学部, その他 2013 – 2014: 旭川医科大学, 医学部, 特任講師 2013: 旭川医科大学, 医学邪, 特任助教 2011 – 2012: 旭川医科大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Experimental pathology / Tumor diagnostics / Clinical oncology Except Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology / Hematology / Basic Section 49030:Experimental pathology-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Basic Section 59010:Rehabilitation science-related / Basic Section 54010:Hematology and medical oncology-related / Legal medicine
Keywords	Principal Investigator 血小板 / 肝がん / 肝癌 / 鉄 / 骨格筋 / 脂肪性肝炎 / 骨格筋萎縮 / FGF9 / 非アルコール性脂肪性肝疾患 / 非アルコール性脂肪肝炎 … More / エネルギー代謝 / コレステロール合成 / 脂質代謝 / 鉄過剰 / HIF-1 alpha / HIF-1α / HIF-1alpha … More Except Principal Investigator 鉄 / 血小板 / 肝硬変 / 胆管癌 / 原発性肝癌 / 分化転換」 / 脱分化 / 分化転換 / 混合型肝癌 / 胆管細胞癌 / 肝細胞癌 / 肝腫瘍 / 副作用 / エピゲノム / 死後脳 / 鎮痛薬 / オピオイド / 心機能障害 / 骨格筋再生 / exosome / exosome miRNA / サルコペニア誘導心機能不全 / 不全心筋回復障害 / miRNA / オートファジー / 心臓悪液質 / サルコペニア / 非トランスフェリン結合鉄 / labile plasma iron (LPI) / 非トランスフェリン結合鉄（NTBI） / 抗腫瘍効果 / フェロトーシス / 肝発癌 / 肝線維化 / NASH / プロバイオティクス / 選択的インスリン抵抗性 / インスリン抵抗性 / 腸内細菌 / NAFLD / 臨床 / 細胞・組織 / 遺伝子 / 癌 / メチル化解析 / コピー数多型 / 次世代シーケンサー / 体細胞変異解析 / コピー数変異 / 若年発症 / 感受性遺伝子 / 膵癌 / ダイアリシス / ドパミン / 側坐核 / 薬物依存 / マイクロダイアリシス / 危険ドラッグ / ジフェニジン / cell-based bioassay / ラベルフリー / EPIC / ＥＰＩＣ / ＤＭＲ / ＨＴＳ / Flow cytometry法 / Ｃell-based bioassay / フェロポルチン / ヘプシジン / UPR / 小胞体ストレス / 鉄代謝異常 / 脂肪肝 / 鉄代謝 / クロマトグラフ用樹脂剤 / キレート剤 / NTA / バイオマーカー / 自動分析装置 / HPLC / トランスフェリン / 鉄過剰 / NTBI / 不安定鉄 Less

肝がん関連血小板の獲得形質に介入した新たな治療法の開発Principal Investigator
- Principal Investigator
  
  田中宏樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Asahikawa Medical College
Exploring alterations in platelet function and therapeutic targets in liver cirrhosis
- Principal Investigator
  
  長谷部拓夢
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
DDS using autologous platelets: a new therapeutic strategy to reverse the hepatocarcinoma-platelet interactionPrincipal Investigator
- Principal Investigator
  
  Tanaka Hiroki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Asahikawa Medical College
Mechanisms of gene regulation intrinsic for human brain in opioid adverse efects
- Principal Investigator
  
  笠井慎也
- Project Period (FY)
  2019 – 2023
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
- Research Institution
  Tokyo Metropolitan Institute of Medical Science
Mechanisms determining the wide spectrum of hepatocytic tumors
- Principal Investigator
  
  Nishikawa Yuji
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Asahikawa Medical College
Analysis of hepatic fibrosis and carcinogenesis in NASH by substances derived from microbiota
- Principal Investigator
  
  SAWADA Koji
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Asahikawa Medical College
Anti-tumor effect achieved by effective induction of ferroptosis utilizing non-transferrin-bound iron
- Principal Investigator
  
  IKUTA KATSUYA
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Asahikawa Medical College
Mechanisms of sarcopenia-induced cardiac function alteration and functional improvement via skeletal muscle regeneration in the ischemic heart.
- Principal Investigator
  
  Takehara Naofumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Kyoto Prefectural University of Medicine
  Asahikawa Medical College
Molecular pathology of fatty liver disease learned from the muscle-liver axisPrincipal Investigator
- Principal Investigator
  
  Tanaka Hiroki
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  Asahikawa Medical College
Genetic alterations in early-onset pancreatic cancer
- Principal Investigator
  
  Sasajima Junpei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Evaluation of the neurochemical effects of diphenidine, a new psychoactive substance, on the dopaminergic reward system by using rat brain microdialysis
- Principal Investigator
  
  SHIMIZU Keiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Legal medicine
- Research Institution
  Asahikawa Medical College
ヘプシジン関連創薬のためのＥＰＩＣシステムを応用した活性型ヘプシジン測定系の開発
- Principal Investigator
  
  佐々木勝則
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Asahikawa Medical College
Aberrant energy metabolism induced by iron overload; Analysis for novel carcinogenic factor in liver tissuePrincipal Investigator
- Principal Investigator
  
  Tanaka Hiroki
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor diagnostics
- Research Institution
  Asahikawa Medical College
Iron overload by iron metabolism dysregulation and UPR breakdown through the ER stress
- Principal Investigator
  
  Ohtake Takaaki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Asahikawa Medical College
Nobel quantification system of non-transferrin-bound iron utilizing automated analyzer
- Principal Investigator
  
  SASAKI Katsunori
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Asahikawa Medical College
Inhibition of HIF-1 alpha using a novel Iron facilitator LS5-81 and its anti-cancer activity in hepatocellular carcinomaPrincipal Investigator
- Principal Investigator
  
  TANAKA Hiroki
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Clinical oncology
- Research Institution
  Asahikawa Medical College

[Book] 特別支援教育のための障害理解 : 未来に開かれた教育へ2022
- Author(s)
  濵田豊彦(監), 東京学芸大学特別支援科学講座(編), 田中美歩(分担)
- Total Pages
  284
- Publisher
  金子書房
- ISBN
  9784760828531
- Data Source
  KAKENHI-PROJECT-19KK0225
[Journal Article] Educational challenges for 22q11.2 deletion syndrome in Japan: Findings from a mixed methods survey.2023
- Author(s)
  Tanaka M, Kanehara A, Morishima R, Kumakura Y, Okouchi N, Nakajima N, Hamada J, Ogawa T, Tamune H, Nakahara M, Jinde S, Kano Y, Kasai K.
- Journal Title
  
  J Appl Res Intellect Disabil
  
  Volume: 36 Issue: 3 Pages: 558-570
- DOI
  10.1111/jar.13079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0225
[Journal Article] High levels of Myc expression are required for the robust proliferation of hepatocytes, but not for the sustained weak proliferation2023
- Author(s)
  Goto Masanori、Ooshio Takako、Yamamoto Masahiro、Tanaka Hiroki、Fujii Yumiko、Meng Lingtong、Kamikokura Yuki、Okada Yoko、Nishikawa Yuji
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1869 Issue: 4 Pages: 166644-166644
- DOI
  10.1016/j.bbadis.2023.166644
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20K07558, KAKENHI-PROJECT-23K06667, KAKENHI-PROJECT-20K07443
[Journal Article] Probiotic-derived heptelidic acid exerts antitumor effects on extraintestinal melanoma through glyceraldehyde-3-phosphate dehydrogenase activity control2022
- Author(s)
  Isozaki Shotaro、Konishi Hiroaki、Tanaka Hiroki、Yamamura Chikage、Moriichi Kentaro、Ogawa Naoki、Fujiya Mikihiro
- Journal Title
  
  BMC Microbiology
  
  Volume: 22 Issue: 1 Pages: 110-110
- DOI
  10.1186/s12866-022-02530-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-21K07929, KAKENHI-PROJECT-22K17411
[Journal Article] Influence of Prenatal Drug Exposure, Maternal Inflammation, and Parental Aging on the Development of Autism Spectrum Disorder2022
- Author(s)
  Sato A, Kotajima-Murakami H, Tanaka M, Katoh Y, Ikeda K
- Journal Title
  
  Front Psychiatry
  
  Volume: 13 Pages: 821455-821455
- DOI
  10.3389/fpsyt.2022.821455
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16902, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-23K21457
[Journal Article] Soluble thrombomodulin ameliorates aberrant hemostasis after rewarming in a rat accidental hypothermia model2022
- Author(s)
  Takauji Shuhei、Tanaka Hiroki、Hayakawa Mineji、Horioka Kie、Isozaki Shotaro、Konishi Hiroaki
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 587 Pages: 1-8
- DOI
  10.1016/j.bbrc.2021.11.086
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225
[Journal Article] Medical, welfare, and educational challenges and psychological distress in parents caring for an individual with 22q11.2 deletion syndrome: A cross-sectional survey in Japan.2022
- Author(s)
  Morishima R, Kumakura Y, Usami S, Kanehara A, Tanaka M, Okochi N, Nakajima N, Hamada J, Ogawa T, Ando S, Tamune H, Nakahara M, Jinde S, Kano Y, Tanaka K, Hirata Y, Oka A, Kasai K.
- Journal Title
  
  Am J Med Genet A
  
  Volume: 188 Issue: 1 Pages: 37-45
- DOI
  10.1002/ajmg.a.62485
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19KK0225
[Journal Article] Hypoxia-induced nuclear translocation of β-catenin in the healing process of frostbite2022
- Author(s)
  Isozaki Shotaro、Tanaka Hiroki、Horioka Kie、Konishi Hiroaki、Kashima Shin、Takauji Shuhei、Fujiya Mikihiro、Druid Henrik
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
  
  Volume: 1868 Issue: 6 Pages: 166385-166385
- DOI
  10.1016/j.bbadis.2022.166385
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22K17411
[Journal Article] Interaction between social behavior and paternal age in offspring of the same paternal mice2022
- Author(s)
  Tanaka Miho、Sato Atsushi、Kotajima‐Murakami Hiroko、Kashii Hirofumi、Hagino Yoko、Ide Soichiro、Ikeda Kazutaka
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: 42 Issue: 3 Pages: 343-346
- DOI
  10.1002/npr2.12258
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06814, KAKENHI-PROJECT-22K07340, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19K16902, KAKENHI-PROJECT-23K21457
[Journal Article] 肝・骨格筋軸に着目した脂肪性肝炎の新規治療薬開発2021
- Author(s)
  田中宏樹.
- Journal Title
  
  化学工業　特集/創薬を支える独創的な技術開発
  
  Volume: 72 Pages: 38-43
- Data Source
  KAKENHI-PROJECT-19KK0225
[Journal Article] Treatment of hepatocellular carcinoma with autologous platelets encapsulating sorafenib or lenvatinib: A novel therapy exploiting tumor‐platelet interactions2021
- Author(s)
  Tanaka Hiroki、Horioka Kie、Hasebe Takumu、Sawada Koji、Nakajima Shunsuke、Konishi Hiroaki、Isozaki Shotaro、Goto Masanori、Fujii Yumiko、Kamikokura Yuki、Ogawa Katsuhiro、Nishikawa Yuji
- Journal Title
  
  International Journal of Cancer
  
  Volume: 150 Issue: 10 Pages: 1640-1653
- DOI
  10.1002/ijc.33915
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-21K07167, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-21K17328, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-22K17411
[Journal Article] Bacteria-derived ferrichrome inhibits tumor progression in sporadic colorectal neoplasms and colitis-associated cancer.2021
- Author(s)
  Iwama T, Fujiya M, Konishi H, Tanaka H, Murakami Y, Kunogi T, Sasaki T, Takahashi K, Ando K, Ueno N, Kashima S, Moriichi K, Tanabe H, Okumura T.
- Journal Title
  
  Cancer Cell Int
  
  Volume: 21 Issue: 1 Pages: 21-21
- DOI
  10.1186/s12935-020-01723-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19K17419
[Journal Article] Probiotic derived polyphosphate accelerates intestinal epithelia wound healing through inducing platelet-derived mediators.2021
- Author(s)
  Isozaki S, Konishi H, Fujiya M, Tanaka H, Murakami Y, Kashima S, Ando K, Ueno N, Moriichi K, Okumura T.
- Journal Title
  
  Mediators of Inflammation
  
  Volume: 2021:5582943 Pages: 1-14
- DOI
  10.1155/2021/5582943
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-19K17419
[Journal Article] Sarcopenia-derived exosomal micro-RNA 16-5p disturbs cardio-repair via a pro-apoptotic mechanism in myocardial infarction in mice2021
- Author(s)
  Hayasaka Taiki、Takehara Naofumi、Aonuma Tatsuya、Kano Kohei、Horiuchi Kiwamu、Nakagawa Naoki、Tanaka Hiroki、Kawabe Jun-ichi、Hasebe Naoyuki
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 19163-19163
- DOI
  10.1038/s41598-021-98761-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K10737, KAKENHI-PROJECT-19K19824, KAKENHI-PROJECT-21K08021
[Journal Article] Impaired wakefulness and rapid eye movement sleep in dopamine-deficient mice2021
- Author(s)
  Kashiwagi Mitsuaki、Kanuka Mika、Tanaka Kaeko、Fujita Masayo、Nakai Ayaka、Tatsuzawa Chika、Kobayashi Kazuto、Ikeda Kazutaka、Hayashi Yu
- Journal Title
  
  Molecular Brain
  
  Volume: 14 Issue: 1 Pages: 170-170
- DOI
  10.1186/s13041-021-00879-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K21456, KAKENHI-PROJECT-20K22674, KAKENHI-PUBLICLY-21H00199, KAKENHI-PUBLICLY-21H00414, KAKENHI-PROJECT-20H03353, KAKENHI-PROJECT-21K15179, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-23K21457
[Journal Article] Decreased Portal Circulation Augments Fibrosis and Ductular Reaction in Nonalcoholic Fatty Liver Disease in Mice2021
- Author(s)
  Meng Lingtong、Goto Masanori、Tanaka Hiroki、Kamikokura Yuki、Fujii Yumiko、Okada Yoko、Furukawa Hiroyuki、Nishikawa Yuji
- Journal Title
  
  The American Journal of Pathology
  
  Volume: 191 Issue: 9 Pages: 1580-1591
- DOI
  10.1016/j.ajpath.2021.06.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03448
[Journal Article] Generation of combined hepatocellular‐cholangiocarcinoma through transdifferentiation and dedifferentiation in p53‐knockout mice2021
- Author(s)
  Liu Yang、Xin Bing、Yamamoto Masahiro、Goto Masanori、Ooshio Takako、Kamikokura Yuki、Tanaka Hiroki、Meng Lingtong、Okada Yoko、Mizukami Yusuke、Nishikawa Yuji
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 8 Pages: 3111-3124
- DOI
  10.1111/cas.14996
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03448, KAKENHI-PROJECT-20K07558
[Journal Article] Low temperature induces von-willebrand factor expression via increased early growth response 1 transcriptional activity in splenic sinusoidal endothelial cells.2020
- Author(s)
  Horioka K, Tanaka H, Isozaki S, Konishi H, Addo L, Takauji S, Druid H.
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 526 Issue: 1 Pages: 239-245
- DOI
  10.1016/j.bbrc.2020.03.073
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225
[Journal Article] Postoperative improvement of executive function and adaptive behavior in children with intractable epilepsy2020
- Author(s)
  Ueda R, Kaga Y, Kita Y, Tanaka M, Iwasaki M, Takeshita E, Shimizu-Motohashi Y, Ishiyama A, Saito T, Nakagawa E, Sugai K, Sasaki M, Okada T, Inagaki M.
- Journal Title
  
  Brain Dev.
  
  Volume: 2 Issue: 2 Pages: 280-287
- DOI
  10.1016/j.braindev.2020.08.005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08044, KAKENHI-PROJECT-20K07917, KAKENHI-PROJECT-19K02943, KAKENHI-PROJECT-19KK0225
[Journal Article] Acute Colchicine Poisoning Causes Endotoxemia via the Destruction of Intestinal Barrier Function: The Curative Effect of Endotoxin Prevention in a Murine Model.2020
- Author(s)
  Horioka K, Tanaka H, Isozaki S, Konishi H, Fujiya M, Okuda K, Asari M, Shiono H, Ogawa K, Shimizu K
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 65 Issue: 1 Pages: 132-140
- DOI
  10.1007/s10620-019-05729-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19KK0225
[Journal Article] A tumor-specific modulation of heterogeneous ribonucleoprotein A0 promotes excessive mitosis and growth in colorectal cancer cells.2020
- Author(s)
  Konishi H, Fujiya M, Kashima S, Sakatani A, Dokoshi T, Ando K, Ueno N, Iwama T, Moriichi K, Tanaka H, Okumura T
- Journal Title
  
  Cell Death & Disease
  
  Volume: 11 Issue: 4 Pages: 245-245
- DOI
  10.1038/s41419-020-2439-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17419, KAKENHI-PROJECT-17K15911, KAKENHI-PROJECT-19KK0225
[Journal Article] Rewarming from accidental hypothermia enhances whole blood clotting properties in a murine model2020
- Author(s)
  Horioka Kie、Tanaka Hiroki、Isozaki Shotaro、Konishi Hiroaki、Addo Lynda、Takauji Shuhei、Druid Henrik
- Journal Title
  
  Thrombosis Research
  
  Volume: 195 Pages: 114-119
- DOI
  10.1016/j.thromres.2020.07.022
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K19477, KAKENHI-PROJECT-19KK0225
[Journal Article] Probiotic-derived ferrichrome inhibits the growth of refractory pancreatic cancer cells.2020
- Author(s)
  Kita A, Fujiya M, Konishi H, Tanaka H, Kashima S, Iwama T, Ijiri M, Murakami Y, Takauji S, Goto T, Sakatani A, Ando K, Ueno N, Ogawa N, Okumura T.
- Journal Title
  
  Int J Oncol
  
  Volume: 57 Issue: 3 Pages: 721-732
- DOI
  10.3892/ijo.2020.5096
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K07927, KAKENHI-PROJECT-19K16484, KAKENHI-PROJECT-19K17419, KAKENHI-PROJECT-19KK0225, KAKENHI-PROJECT-18K15770
[Journal Article] Autofluorescence Imaging Reflects the Nuclear Enlargement of Tumor Cells as well as the Cell Proliferation Ability and Aberrant Status of the p53, Ki-67, and p16 Genes in Colon Neoplasms2019
- Author(s)
  Moriichi K, Fujiya M, Kobayashi Y, Murakami Y, Iwama T, Kunogi T, Sasaki T, Ijiri M, Takahashi K, Tanaka K, Sakatani A, Ando K, Nomura Y, Ueno N, Kashima S, Ikuta K, Tanabe H, Mizukami Y, Saitoh Y, Okumura T.
- Journal Title
  
  Molecules
  
  Volume: 24 Issue: 6 Pages: 1106-1106
- DOI
  10.3390/molecules24061106
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09472, KAKENHI-PROJECT-18K08347, KAKENHI-PROJECT-18K15770, KAKENHI-PROJECT-19K17419, KAKENHI-PROJECT-17K15911
[Journal Article] Novel Automated Measuring System for Evaluating Labile Plasma Iron in Serum2019
- Author(s)
  Saito T, Ikuta K, Hatayama M, Shibusa K, Matsui K, Tanaka R, Toki Y, Kato D, Iizuka N, Okumura T.
- Journal Title
  
  Annals of Clinical Biochemistry
  
  Volume: 56 (6) Issue: 6 Pages: 654-661
- DOI
  10.1177/0004563219861413
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08347, KAKENHI-PROJECT-17K08971
[Journal Article] Comparative genome-wide analysis of gastric adenocarcinomas with hyperplastic polyp components2019
- Author(s)
  Yoshiyasu Takayama, Yusuke Ono, Yusuke Mizukami, Hideaki Itoh, Nozomi Nakajima, Hideo Arai, Shinya Tanaka, Sumihito Nobusawa, Hideaki Yokoo, Yasuhiro Onozato
- Journal Title
  
  Virchows Arch
  
  Volume: 475 Issue: 3 Pages: 383-389
- DOI
  10.1007/s00428-019-02592-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09451, KAKENHI-PROJECT-17K09472
[Journal Article] Hepatic nerve growth factor induced by iron overload triggers defenestration in liver sinusoidal endothelial cells.2015
- Author(s)
  Addo L, Tanaka H, Yamamoto M, Toki Y, Ito S, Ikuta K, Sasaki K, Ohtake T, Torimoto Y, Fujiya M, Kohgo Y.
- Journal Title
  
  Biochim Biophys Acta
  
  Volume: 1852(1) Issue: 1 Pages: 175-83
- DOI
  10.1016/j.bbadis.2014.11.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25460969
[Journal Article] Augmented hepatic Toll-like receptors by fatty acids trigger the pro-inflammatory state of nonalcoholic fatty liver disease in mice.2014
- Author(s)
  Sawada K, Ohtake T, Hasebe T, Abe M, Tanaka H, Ikuta K, Suzuki Y, Fujiya M, Hasebe C, Kohgo Y.
- Journal Title
  
  Hepatology Research
  
  Volume: in press Issue: 8 Pages: 920-34
- DOI
  10.1111/hepr.12199
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931, KAKENHI-PROJECT-25460969, KAKENHI-PROJECT-26870026
[Journal Article] Up-regulation of iron regulatory hormone hepcidin by interferon α.2014
- Author(s)
  Ichiki K, Ikuta K, Addo L, Tanaka H, Sasaki Y, Shimonaka Y, Sasaki K, Ito S, Shindo M, Ohtake T, Fujiya M, Torimoto Y, Kohgo Y.
- Journal Title
  
  Journal of Gastroenterology and Hepatology
  
  Volume: 29 Issue: 2 Pages: 387-394
- DOI
  10.1111/jgh.12348
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22390148, KAKENHI-PROJECT-23590931, KAKENHI-PROJECT-24591377, KAKENHI-PROJECT-25460969
[Journal Article] Iron facilitator LS081 reduces Hypoxia inducible factor-1α protein and functions as anti-cancer agent in hepatoma2012
- Author(s)
  Tanaka H, Li Z, Ikuta K,Addo L, et al.
- Journal Title
  
  Cancer Science
  
  Volume: 103 Issue: 4 Pages: 767-774
- DOI
  10.1111/j.1349-7006.2011.02192.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790902, KAKENHI-PROJECT-23701094
[Journal Article] Anticancer activity of the iron facilitator LS0812011
- Author(s)
  Li Z, Tanaka H, Galiano F, Glass J
- Journal Title
  
  J Exp Clin Cancer Res
  
  Volume: 31 Issue: 1 Pages: 30-34
- DOI
  10.1186/1756-9966-30-34
- Data Source
  KAKENHI-PROJECT-23701094
[Journal Article] Improved quantification for non-transferrin-bound iron measurement using high-performance liquid chromatography by reducing iron contamination2011
- Author(s)
  Sasaki K, Ikuta K, et al
- Journal Title
  
  Mol Med Reports
  
  Volume: 4 Pages: 913-918
- DOI
  10.3892/mmr.2011.518
- NAID
  120004461831
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21790902, KAKENHI-PROJECT-23591363
[Journal Article] Improved quantification for non-transferrin-bound iron measurement using high performance liquid chromatography by reducing iron contamination2011
- Author(s)
  Katsunori Sasaki, Katsuya Ikuta, Hiroki Tanaka, Takaaki Ohtake, Yoshihiro Torimoto, Mikihiro Fujuya and Yutaka Kohgo
- Journal Title
  
  Mol. Med. Reports
  
  Volume: 4 Pages: 913-918
- NAID
  120004461831
- Data Source
  KAKENHI-PROJECT-23591363
[Patent] 肝細胞における脂肪蓄積量を低減させるための脂肪低減剤及び血中コレステロール低減剤2017
- Inventor(s)
  田中宏樹
- Industrial Property Rights Holder
  田中宏樹
- Industrial Property Rights Type
  特許
- Filing Date
  2017
- Overseas
- Data Source
  KAKENHI-PROJECT-17K08779
[Presentation] Tumor-educated plateletsの蛋白質合成能の増強による肝がん進展の促進2023
- Author(s)
  田中宏樹、堀岡希衣、後藤正憲、藤井裕美子、上小倉佑機、西川祐司
- Organizer
  第30回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-21K07167
[Presentation] De novo protein synthesis capacity of Tumor-educated platelets2023
- Author(s)
  Hiroki Tanaka, Kie Horioka
- Organizer
  ISTH 2023 Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07167
[Presentation] 22q11.2欠失症候群のmultimorbidity、三障害併存が医療における困難に与える影響2023
- Author(s)
  田中美歩, 熊倉陽介, 金原明子, 宇野晃人, 澤井大和, 高橋優輔, 柳下祥, 神出誠一郎, 笠井清登.
- Organizer
  第17回日本統合失調症学会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] 慢性肝障害から発生する肝発癌におけるエピゲノム異常2022
- Author(s)
  Hiroki Tanaka, Masanori Goto, Yumiko Fujii, Yuki Kamikokura, Yuji Nishikawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 肝細胞がんにおけるがん遺伝子Mycとプロリン代謝酵素PRODHの関連2022
- Author(s)
  後藤　正憲、田中　宏樹、藤井　裕美子、上小倉　佑機、岡田　陽子、西川　祐司
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 血小板－肝細胞相互作用：ラット肝細胞による血小板由来微小胞の取り込み2022
- Author(s)
  田中宏樹
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-21K07167
[Presentation] Platelet-Derived Microvesicles Promote Selective Cell Viability in Hepatocellular Carcinoma: Differences in Properties between Normal Platelets and Tumor Educated Platelets2022
- Author(s)
  Hiroki Tanaka
- Organizer
  64th ASH annual meeting and exposition
- Data Source
  KAKENHI-PROJECT-21K07167
[Presentation] 肝内胆管細胞における脂質ホスファターゼ SHIP2 の細胞核への集積2022
- Author(s)
  藤井　裕美子、上小倉　佑機、後藤　正憲、人見　淳一、田中　宏樹、岡田　陽子、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 血小板由来微小胞による肝腫瘍細胞の生存能促進2022
- Author(s)
  田中　宏樹、上小倉　佑機、後藤　正憲、藤井　裕美子、西川　祐司
- Organizer
  第29回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス海馬における過成熟現象2022
- Author(s)
  萩原英雄, 小清水久嗣, 服部聡子, 田中美歩, 池田和隆, 宮川剛.
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] マウス肝腫瘍のNotch経路の活性化と胆管癌表現型に対するMycとMycnの影響2022
- Author(s)
  Masanori Goto, Hiroki Tanaka, Yumiko Fujii, Yuki Kamikokura, Yoko Okada, and Yuji Nishikawa
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 血小板－肝細胞相互作用：ラット肝細胞による血小板由来微小胞の取り込み2022
- Author(s)
  田中　宏樹、堀岡　希衣、後藤　正憲、上小倉　佑機、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] GABAA 受容体アンタゴニストのピクロトキシン暴露による仔の自閉症様行動と遺伝子発現解析.2022
- Author(s)
  古田島浩子, 萩原英雄, 佐藤敦志, 萩野洋子, 田中美歩, 加藤喜久, 西藤泰昌, 高松幸雄, 内野茂夫, 宮川剛, 池田和隆.
- Organizer
  BPCNPNPPP4学会合同年会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] 活性型 AKT と YAP で誘導したマウス胆管癌表現型に対する Myc または Mycn の影響2022
- Author(s)
  後藤　正憲、田中　宏樹、藤井　裕美子、上小倉　佑機、岡田　陽子、西川　祐司
- Organizer
  第111回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Exposure to GABAA receptor antagonist picrotoxin in pregnant mice causes autism-like behaviors and aberrant gene expression in offspring.2022
- Author(s)
  Kotajima-Murakami H, Hagihara H, Sato A, Hagino Y, Tanaka M, Katoh Y, Nishito Y, Takamatsu Y, Uchino S, Miyakawa T, Ikeda K.
- Organizer
  NEURO2022
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] 自己血小板によるドラッグデリバリーシステム―肝癌・血小板相互作用を利用した新たな治療戦略―2021
- Author(s)
  田中　宏樹、堀岡　希衣、後藤正憲、人見淳一、藤井　裕美子、上小倉　佑機、孟　玲童、小川　勝洋、西川　祐司
- Organizer
  第110回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Prenatal exposure of GABAA receptor inhibitor picrotoxin causes ASD-like behaviors and aberrant gene expression in mice.2021
- Author(s)
  Kotajima-Murakami H, Hagihara H, Sato A, Hagino Y, Tanaka M, Katoh Y, Nishito Y, Takamatsu Y, Uchino S, Miyakawa T, Ikeda K.
- Organizer
  7th Congress of Asian College of Neuropsychopharmacology (7th Congress of AsCNP)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] 非アルコール性脂肪肝炎の進展における門脈循環障害の意義2021
- Author(s)
  西川祐司、孟玲童、後藤正憲、田中宏樹、上小倉佑機、藤井裕美子、岡田陽子、古川博之
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] マウス肝再生における Myc 依存性、Myc 非依存性の肝細胞増殖機構2021
- Author(s)
  後藤正憲、大塩貴子、山本雅大、藤井裕美子、田中宏樹、上小倉佑機、孟玲童、岡田陽子、西川祐司
- Organizer
  第28回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 自己血小板を用いたドラッグデリバリーシステムの肝細胞癌に対するターゲティング効果2021
- Author(s)
  田中宏樹, 堀岡希衣, 後藤正憲, 人見淳一, 藤井裕美子, 上小倉佑機, 孟玲童, 小川勝洋, 西川祐司
- Organizer
  第80回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-21K07167
[Presentation] 分化転換および脱分化による混合型肝癌の発生：肝細胞特異的p53ノックアウトマウスを用いた検討2021
- Author(s)
  西川祐司，劉洋，辛氷，山本雅大，大塩貴子，後藤正憲，上小倉佑機，田中宏樹，孟玲童，岡田陽子，水上祐輔
- Organizer
  第57回日本肝癌研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 自己血小板を用いたドラッグデリバリーシステムの肝細胞癌に対するターゲティング効果.2021
- Author(s)
  田中宏樹, 堀岡希衣, 後藤正憲, 人見淳一, 藤井裕美子, 上小倉佑機, 孟玲童, 小川勝洋, 西川祐司.
- Organizer
  第80回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] Targeting effect of the autologous platelet-based drug delivery system on hepatocellular carcinoma2021
- Author(s)
  Hiroki Tanaka , Kie Horioka , Masanori Goto , Junichi Hitomi , Yumiko Fujii , Yuki Kamikokura , Lingtong Meng , Katsuhiro Ogawa , Yuji Nishikawa
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 血清中フリー鉄による酸化活性（Labile Plasma Iron）の自動分析装置対応測定2020
- Author(s)
  齋藤豪志、生田克哉、田中利輝、奥村利勝．
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08347
[Presentation] 妊娠マウスへのGABA受容体阻害剤曝露による仔への影響.2020
- Author(s)
  古田島浩子, 佐藤敦志, 萩野洋子, 田中美歩, 加藤喜久, 高松幸雄, 内野茂夫, 池田和隆.
- Organizer
  NPBPPP2020合同年会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] A novel therapeutic strategy for hepatocellular carcinoma based on the tumor-platelet interaction.2020
- Author(s)
  Tanaka H., Horioka K., Goto M., Hitomi J., Fujii Y., Ogawa K., Nishikawa Y.
- Organizer
  第79回日本癌学会学術集会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] p53欠損マウス肝細胞のin vitro形質転換：肝内移植で形成される腫瘍の表現型と間質の状態変化の関連2020
- Author(s)
  上小倉佑機，後藤正憲，人見淳一，藤井裕美子，田中宏樹，渡邉賢二，大塩貴子，山本雅大，孟玲童，岡田陽子，西川祐司
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Amelioration of the Pathologic Changes in the Hepatocyte-Specific BRAFV600E Mutated Mice by Administration of Aspirin.2020
- Author(s)
  Tanaka H., Horioka K., Yamamoto M., Yamazaki K., Ogawa K.
- Organizer
  The International Society on Thrombosis and Haemostasis (ISTH) Virtual Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] 腫瘍・血小板相互作用を利用した肝癌に対する新規治療法2020
- Author(s)
  田中宏樹、堀岡希衣、長谷部拓夢、中嶋駿介、澤田康司、小川勝洋、西川祐司
- Organizer
  第27回肝細胞研究会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Exposure of picrotoxin, a GABAA receptor antagonist, in pregnant mice causes ASD-like behaviors in offspring.2020
- Author(s)
  Kotajima H, Sato A, Hagino Y, Tanaka M, Kato Y, Takamatsu Y, Uchino S, Ikeda K.
- Organizer
  59th Annual Meeting of The American College of Neuropsychopharmacology (ACNP 2020) Virtual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] Lactobacillus brevis SBC8803はNAFLDにおける選択的インスリン抵抗性を部分的に改善させる2020
- Author(s)
  澤田康司、田中宏樹、林秀美、長谷部拓夢、中嶋駿介、藤谷幹浩、奥村利勝
- Organizer
  JDDW2020
- Data Source
  KAKENHI-PROJECT-18K07991
[Presentation] 肝特異的ヒトBRAFV600E変異発現トランスジェニックマウスに見られた異常血小板増多症2020
- Author(s)
  田中宏樹，堀岡希衣，山崎弘資，西川祐司，小川勝洋
- Organizer
  第53回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] 発がんの分子病理学～なぜがんゲノム検査が必要か？～2020
- Author(s)
  田中宏樹
- Organizer
  第5回細胞研究会勉強会
- Invited
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] p53ノックアウトマウス肝細胞のin vitro形質転換による胆管癌および混合型肝癌細胞株の樹立2020
- Author(s)
  上小倉佑機、後藤正憲、人見淳一、藤井裕美子、田中宏樹、渡邉賢二、大塩貴子、山本雅大、孟玲童、岡田陽子、西川祐司
- Organizer
  第109回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Exposure of GABA receptor inhibitor picrotoxin in pregnant mice causes ASD-like behaviors in offspring.2020
- Author(s)
  Kotajima H, Sato A, Hagino Y, Tanaka M, Kato Y, Takamatsu Y, Uchino S, Ikeda K.
- Organizer
  第43回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] 非アルコール性脂肪性肝疾患の進展に対する門脈循環障害の影響2020
- Author(s)
  孟玲童，後藤正憲，上小倉佑機，田中宏樹，藤井裕美子，人見淳一，岡田陽子，西川祐司
- Organizer
  第53回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] Exposure of pregnant mice to GABA receptor inhibitor picrotoxin causes ASD-like behaviors in offspring.2020
- Author(s)
  Kotajima H, Sato A, Hagino Y, Tanaka M, Kato Y, Takamatsu Y, Uchino S, Ikeda K.
- Organizer
  The International College of Neuropsychopharmacology (CINP2021) Virtual Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] The effects and underling mechanisms of Lactobacillus brevis SBC8803 monotherapy on a mouse model of non-alcoholic fatty liver disease2020
- Author(s)
  Koji Sawada, Hiroki Tanaka, Hidemi Hayashi, Takumu Hasebe, Shunsuke Nakajima, Mikihiro Fujiya, Toshikatsu Okumura.
- Organizer
  AASLD 2020, The Liver Meeting Digital Experience
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07991
[Presentation] 腫瘍・血小板相互作用を利用した肝癌に対する新規治療法2020
- Author(s)
  田中宏樹，堀岡希衣，後藤正憲，人見淳一，藤井裕美子，上小倉佑機，孟玲童，小川勝洋，西川祐司
- Organizer
  第122回北海道癌談話会例会
- Data Source
  KAKENHI-PROJECT-19H03448
[Presentation] mTOR signaling pathway plays a key role in non-syndromic autism spectrum disorder.2019
- Author(s)
  Kotajima H, Kobayashi T, Sato A, Hagino Y, Tanaka M, Nishito Y, Takamatsu Y, Uchino S, Ikeda K.
- Organizer
  6th Congress of Asian College of Neuropsychopharmacology (AsCNP2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19KK0225
[Presentation] デジタルPCRによるBRAF遺伝子変異検査は甲状腺乳頭癌のFNA正診率を向上させる BRAF mutation testing by dPCR improves the diagnosis accuracy of FNA for the papillary thyroid carcinoma2019
- Author(s)
  北崎アリサ、駒林優樹、小野裕介、木村太一、田中伸哉、長嶋和郎、水上裕輔.
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K09451
[Presentation] ABNORMAL ACTIVATION OF HNRNPA0 INHIBITS CANCER CELL APOPTOSIS AND PROMOTES EXCESSIVE MITOSIS IN CANCER CELLS.2019
- Author(s)
  Konishi H, Fujiya M, Kita A, Tanaka H, Kashima S, Sakatani A, Dokoshi T, Ando K, Ueno N, Moriichi K, Iwama T, Takahashi K, Murakami Y, Ikuta K, Mizukami Y, Goto T, Okumura T.
- Organizer
  DDW2019米国消化器病週間
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09451
[Presentation] PATHWAYS OF PROGRESSION FROM INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM AND THE GENETIC DIVERSITY OF ASSOCIATED ORGAN FIELD.2019
- Author(s)
  Mizukami Y, Omori Y, Ono Y, Karasaki H, Tanino M, Yamaguchi H, Furukawa T, Maguchi H, Tanaka S, Okumura T
- Organizer
  DDW2019米国消化器病週間
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09451
[Presentation] Mechanistic study of diphenidine, a new psychoactive substance, for the neurochemical effect by using rat brain microdialysis2018
- Author(s)
  Katsuhiro Okuda, Masaru Asari, Hiroki Tanaka, Shotaro Isozaki, Hiromi Yamada, Kie Horioka, Ayaka Yoshida, Kazuo Matsubara, Hiroshi Shiono, Keiko Shimizu
- Organizer
  24th Congress of the International Academy of Legal Medicine
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09197
[Presentation] NAFLDにおけるLactobacillus brevis SBL8803の有用性に関する検討2018
- Author(s)
  澤田康司、田中宏樹、林秀美、長谷部拓夢、中嶋駿介、生田克哉、藤谷幹浩、奥村利勝
- Organizer
  第42回日本肝臓学会東部会
- Data Source
  KAKENHI-PROJECT-18K07991
[Presentation] Evaluation of the neurochemical effects of diphenidine, a new psychoactive substance, on the dopaminergic reward system by using rat brain microdialysis2017
- Author(s)
  Okuda K, Tanaka H, Asari M, Horioka K, Matsubara K, Shiono H, Shimizu K
- Organizer
  Neuroscience 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09197
[Presentation] ラット脳マイクロダイアリシスによるジフェニジンの脳内報酬系への影響評価2017
- Author(s)
  奥田勝博, 田中宏樹, 浅利　優, 堀岡希衣, 早川　輝, 磯崎翔太郎, 吉田あやか, 松原和夫, 塩野　寛, 清水惠子
- Organizer
  第101次日本法医学会学術全国集会
- Data Source
  KAKENHI-PROJECT-16K09197
[Presentation] 肝発癌における鉄過剰の新たな役割：鉄過剰が引き起こす脂質代謝異常を介した細胞増殖シグナルの亢進2015
- Author(s)
  田中宏樹，澤田康司，長谷部拓夢，佐々木勝則，藤谷幹浩，大竹孝明，高後裕
- Organizer
  第26回日本消化器癌発生学会総会
- Place of Presentation
  米子市
- Year and Date
  2015-11-19
- Data Source
  KAKENHI-PROJECT-26830092
[Presentation] Fatty acids induce the expression of TLRs as the pro-inflammatory state in NAFLD mice liver.2013
- Author(s)
  Sawada K, Ohtake T, Hasebe T, Nakajima S, Abe M, Tanaka H, Kohgo Y.
- Organizer
  The 64th Annual Meeting of American Association for the Study of Liver Diseases.
- Place of Presentation
  Washington, DC
- Data Source
  KAKENHI-PROJECT-25460969
[Presentation] Nobel quantification system of non-transferrin-bound iron (NTBI) utilizing automatic analyzer2013
- Author(s)
  Katsuya Ikuta, Satoshi Ito, Lynda Addo, Mayumi Hatayama, Yasumichi Toki, Junki Inamura, Motohiro Shindo, Hiroki Tanaka, Katsunori Sasaki, Yoshihiro Torimoto, Yutaka Kohgo
- Organizer
  2013 IBIS Meeting BioIron
- Place of Presentation
  London, UK
- Data Source
  KAKENHI-PROJECT-23591363
[Presentation] Nobel quantification system for non-transferrin-bound iron utilizing automated analyzer2013
- Author(s)
  Junki Inamura, Katsuya Ikuta, Daisuke Kato, Naomi Iizuka, Yasumichi Toki, Satoshi Ito, Hiroki Tanaka, Katsunori Sasaki, Motohiro Shindo, Yoshihiro Torimoto, Yutaka Kohgo
- Organizer
  第75回日本血液学会学術集会(JSH2013)
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591363
[Presentation] Nobel quantification system for non-transferrin-bound iron utilizing automated analyzer2013
- Author(s)
  Junki Inamura, Katsuya Ikuta, Daisuke Kato, Naomi Iizuka, Yasumichi Toki, Satoshi Ito, Hiroki Tanaka, Katsunori Sasaki, Motohiro Shindo, Yoshihiro Torimoto, Yutaka Kohgo
- Organizer
  第75回日本血液学会学術集会（JSH2013）
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591363
[Presentation] Non-metal HPLCを用いた高感度NTBI測定法の確立2012
- Author(s)
  佐々木勝則、生田克哉、田中宏樹、大竹孝明、藤谷幹浩、鳥本悦宏、高後裕
- Organizer
  日本薬学会第132年会
- Place of Presentation
  北海道大学（札幌市）
- Data Source
  KAKENHI-PROJECT-23591363
[Presentation] Non-metal HPLCを用いた高感度NTBI測定法の確立佐々木勝則2012
- Author(s)
  生田克哉,田中宏樹,大竹孝明,藤谷幹浩,鳥本悦宏,高後裕
- Organizer
  日本薬学会第132年会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23591363
[Presentation] 慢性肝障害に伴う鉄沈着における組織内低酸素の役割2012
- Author(s)
  田中　宏樹，神田　裕介，知念　日菓利，野崎　大蔵，加藤　大介，アド　リンダ，伊藤　巧，岡村　直香，生田　克哉，大竹　孝明，佐々木　勝則，尾崎　充彦，鳥本　悦宏，高後　裕，岡田　太
- Organizer
  第36回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  札幌市
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] A novel iron facilitator LS081 inhibits HIF-1α protein expression and functions as an anticancer agent2011
- Author(s)
  田中宏樹
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] Reliable quantification of non-transferrin-bound iron (NTBI) in healthy volunteers by improved high sensitive method using HPLC2011
- Author(s)
  Takaaki Hosoki, Katsuya Ikuta, Takaaki Ohtake, Hiroki Tanaka, Katsunoti Sasaki, Yoshihiro Torimoto and Yutaka Kohgo
- Organizer
  2011 IBIS Meeting BioIron
- Place of Presentation
  Vancouver, Canada
- Data Source
  KAKENHI-PROJECT-23591363
[Presentation] A novel iron facilitator LS081 inhibits HIF-1 α protein expression and functions as an anticancer agent2011
- Author(s)
  田中宏樹,生田克哉,佐々木勝則,細木卓明,鳥本悦宏,中村正雄,阿久津弘明,Zhen Li,Jonathan Glass,高後裕
- Organizer
  第70回日本癌学会学術集会
- Place of Presentation
  名古屋市
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] 新規鉄輸送促進剤LS081によるHIF-1αを標的とした肝癌治療効果2011
- Author(s)
  田中宏樹,生田克哉,山本昌代、安藤勝祥、河本徹、岡村直香、伊藤貴博、中村正雄,阿久津弘明,佐々木勝則,鳥本悦宏,Zhen Li,Jonathan Glass,高後裕
- Organizer
  第9回日本臨床腫瘍学会学術集会
- Place of Presentation
  横浜市
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] Glass J A novel iron facilitator LS081 inhibits HIF-1α protein expression and functions as an anticancer agent Podium presentation, Fourth Congress of the International BioIron Society (IBIS)2011
- Author(s)
  Tanaka H, Ikuta K, Hosoki T, Sasaki K, Nakamura M, Akutsu H, Torimoto Y, Kohgo Y, Li Z
- Organizer
  Biennial World Meeting 2011
- Place of Presentation
  Vncouver, BC, Canada
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] A novel iron facilitator LS081 inhibits HIF-1α protein expression and functions as an anticancer agent2011
- Author(s)
  田中宏樹
- Organizer
  Fourth Congress of the International BioIron Society (IBIS) Biennial World Meeting 2011
- Place of Presentation
  バンクーバー
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] Iron uptake facilitator LS5-81 のHIF-1α発現抑制効果2010
- Author(s)
  田中宏樹,生田克哉,佐々木勝則,細木卓明,鳥本悦宏,中村正雄,阿久津弘明,Zhen Li,Jonathan Glass,高後裕
- Organizer
  第34回日本鉄バイオサイエンス学会学術集会
- Place of Presentation
  東京都
- Data Source
  KAKENHI-PROJECT-23701094
[Presentation] Iron-overload alters lipid metabolism and Ras signaling independent of oxidative stress in mouse liver tissue by whole RNA sequencing
- Author(s)
  Hiroki Tanaka, Takaaki Ohtake, Lynda Addo, Masayo Yamamoto, Yasumichi Toki, Koji, Sawada, Synsuke Nakajima, Takumu Hasebe, Katsuya Ikuta, Katsunori Sasaki, Yoshihiro Torimoto, Mikihiro Fujiya, Yutaka Kohgo
- Organizer
  The liver meeting 2014
- Place of Presentation
  Boston
- Year and Date
  2014-11-07 – 2014-11-11
- Data Source
  KAKENHI-PROJECT-26830092
[]
[]

1. SASAKI Katsunori (60336394)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
2. IKUTA Katsuya (00396376)

# of Collaborated Projects: 3 results

# of Collaborated Products: 11 results
3. OHTAKE Takaaki (10359490)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
4. KOHGO Yutaka (10133183)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
5. SHIMIZU Keiko (90312462)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
6. SAWADA Koji (80548660)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. 奥田勝博 (00389115)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
8. 浅利優 (40360979)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
9. 長谷部拓夢 (10596282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
10. Sasajima Junpei (80451467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. Takehara Naofumi (90374793)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. Nishikawa Yuji (90208166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 21 results
13. 水上裕輔 (30400089)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
14. 小野裕介 (40742648)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
15. 土岐康通 (90596280)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
16. 齋藤豪志 (80837930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
17. 川辺淳一 (10400087)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. 笠井慎也 (20399471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
19. 池田和隆 (60281656)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
20. 村上浩子 (60619592)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
21. 田中美歩 (40788155)

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
22. 後藤正憲 (00432203)

# of Collaborated Projects: 1 results

# of Collaborated Products: 19 results
23. 藤井裕美子 (30722334)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
24. 人見淳一 (40568664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
25. 堀岡希衣 (20897730)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. MATSUBARA Kazuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
27. UENO Nobuhiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
28. HAYASHI Yu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
29. IDE Soichiro

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
30. 藤谷幹浩

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
31. 磯崎翔太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
32. 小西弘晃

# of Collaborated Projects: 0 results

# of Collaborated Products: 7 results
33. 盛一健太郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
34. 岡田俊

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tanaka Hiroki 田中 宏樹

TANAKA Hiroki 田中 宏樹

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肝がん関連血小板の獲得形質に介入した新たな治療法の開発Principal Investigator

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DDS using autologous platelets: a new therapeutic strategy to reverse the hepatocarcinoma-platelet interactionPrincipal Investigator

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Molecular pathology of fatty liver disease learned from the muscle-liver axisPrincipal Investigator

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Aberrant energy metabolism induced by iron overload; Analysis for novel carcinogenic factor in liver tissuePrincipal Investigator

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Tanaka Hiroki 田中宏樹

TANAKA Hiroki 田中宏樹