• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

LI HENG  李 コウ

ORCIDConnect your ORCID iD *help
… Alternative Names

LI Heng  李 コウ

Less
Researcher Number 70621994
Other IDs
Affiliation (Current) 2025: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 病態生化学研究部, 科研費研究員
Affiliation (based on the past Project Information) *help 2023: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 病態生化学研究部, 科研費研究員
2016 – 2022: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 疾病研究第二部, 科研費研究員
2015: 国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所知的障害研究部, 科研費研究員
2015: 国立研究開発法人国立精神・神経医療研究センター, 精神保健研究所・知的障害研究部, 流動研究員
2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所 疾病研究第2部, 科研費研究員 … More
2014: 独立行政法人国立精神・神経医療研究センター, 神経研究所疾病研究第二部, 科研費研究員
2013 – 2014: 独立行政法人国立精神・神経医療研究センター, 精神保健研究所 知的障害研究部, 科研費研究員
2013: 独立行政法人国立精神・神経医療研究センター, 精神保健研究所知的障害研究部, 流動研究員
2012: 独立行政法人国立精神・神経医療研究センター, その他部局等, 研究員 Less
Review Section/Research Field
Principal Investigator
Basic Section 52050:Embryonic medicine and pediatrics-related / Pediatrics / Biomedical engineering/Biological material science
Except Principal Investigator
Psychiatric science
Keywords
Principal Investigator
大脳白質形成不全症 / Pelizaeus-Merzbacher病 / 小胞体 / カルシウム恒常性 / 髄鞘形成不全 / ペリツェウス・メルツバッハー病 / 神経変性 / 先天性大脳白質形成不全 / ミトコンドリア / ミトコンドリア機能障害 … More / 小胞体カルシウム枯渇 / 細胞病態 / カルシウム / 膜輸送 / ER-Golgi輸送 / カルシウム枯渇 / 細胞内輸送 / 神経障害 / 病態解析 / 胎児低酸素症 / 胎児低酸素血症 / 胎児脳 / 人工赤血球 … More
Except Principal Investigator
GABA神経系 / 不安 Less
  • Research Projects

    (5 results)
  • Research Products

    (13 results)
  • Co-Researchers

    (8 People)
  •  カルシウム恒常性障害に着目した先天性大脳白質形成不全症の新規細胞病態の解明Principal Investigator

    • Principal Investigator
      李 コウ
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Center of Neurology and Psychiatry
  •  The study of novel cell pathology of congenital dysplasia of cortical white matter focusing on globally impaired membrane traffickingPrincipal Investigator

    • Principal Investigator
      Li Heng
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 52050:Embryonic medicine and pediatrics-related
    • Research Institution
      National Center of Neurology and Psychiatry
  •  The study of neurodegeneration as a prognostic factor in congenital dysplasia of cortical white matterPrincipal Investigator

    • Principal Investigator
      Li Heng
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Pediatrics
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Identification of anxiety induced gene and therapeutic approach

    • Principal Investigator
      Inagaki Masumi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Psychiatric science
    • Research Institution
      National Center of Neurology and Psychiatry
  •  Development of a novel therapy for fetal hypoxia used by artificial oxygen carriers (hemoglobin vesicles)Principal Investigator

    • Principal Investigator
      LI Heng
    • Project Period (FY)
      2012 – 2014
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biomedical engineering/Biological material science
    • Research Institution
      National Center of Neurology and Psychiatry

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2013

All Journal Article Presentation

  • [Journal Article] Abnormality in GABAergic postsynaptic transmission associated with anxiety in Bronx waltzer mice with an Srrm4 mutation2024

    • Author(s)
      Shirakawa Yuka, Li Heng, Inoue Yuki, Izumi Hitomi, Kaga Yoshimi, Goto Yu-ichi, Inoue Ken, Inagaki Masumi
    • Journal Title

      IBRO Neuroscience Reports

      Volume: 16 Pages: 67-77

    • DOI

      10.1016/j.ibneur.2023.12.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K13967, KAKENHI-PROJECT-22K07900, KAKENHI-PROJECT-21H02886
  • [Journal Article] POLR1C variants dysregulate splicing and cause hypomyelinating leukodystrophy2020

    • Author(s)
      Kashiki Hitoshi、Li Heng、Miyamoto Sachiko、Ueno Hiroe、Tsurusaki Yoshinori、Ikeda Chizuru、Kurata Hirofumi、Okada Takumi、Shimazu Tomoyuki、Imamura Hoseki、Enomoto Yumi、Takanashi Jun-ichi、Kurosawa Kenji、Saitsu Hirotomo、Inoue Ken
    • Journal Title

      Neurology Genetics

      Volume: 6 Issue: 6 Pages: 1-7

    • DOI

      10.1212/nxg.0000000000000524

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K08237, KAKENHI-PROJECT-19K08358, KAKENHI-PROJECT-20H03641, KAKENHI-PROJECT-19K22606
  • [Journal Article] Gene suppressing therapy for Pelizaeus-Merzbacher disease using artificial microRNA2019

    • Author(s)
      Li Heng、Okada Hironori、Suzuki Sadafumi、Sakai Kazuhisa、Izumi Hitomi、Matsushima Yukiko、Ichinohe Noritaka、Goto Yu-ichi、Okada Takashi、Inoue Ken
    • Journal Title

      JCI Insight

      Volume: 4 Issue: 10 Pages: 125052-125052

    • DOI

      10.1172/jci.insight.125052

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-16H05361, KAKENHI-PROJECT-16K19679, KAKENHI-PROJECT-19K08358, KAKENHI-PROJECT-17H00892, KAKENHI-PROJECT-19K22606
  • [Presentation] Mitochondrial dysfunction via calcium homeostasis disruption as a cellular pathogenesis of Pelizaeus-Merzbacher Disease2023

    • Author(s)
      Heng Li, Reiko Mishima, Ken Inoue
    • Organizer
      第46回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K07900
  • [Presentation] Globally impaired ER-Golgi trafficking via ER calcium depletion as a cellular pathogenesis of Pelizaeus-Merzbacher Disease2022

    • Author(s)
      Heng Li, Reiko Mishima, Yu-ichi Goto, Ken Inoue
    • Organizer
      第45回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-22K07900
  • [Presentation] Impairment ER-Golgi trafficking via ER calcium depletion as a cellular pathogenesis of Pelizaeus-Merzbacher Disease2021

    • Author(s)
      Heng Li, Yu-ichi Goto, Ken inoue
    • Organizer
      第44回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K08358
  • [Presentation] Globally impaired ER-Golgi trafficking as a cellular pathogenesis of Pelizaeus-Merzbacher disease2020

    • Author(s)
      Heng Li, Yu-ichi Goto, Ken Inoue
    • Organizer
      第43回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19K08358
  • [Presentation] Gene suppressing therapy for Pelizaeus Merzbacher disease using artificial miRNA2019

    • Author(s)
      Heng Li, Hironori Okada, Sadafumi Suzuki, Kazuhisa Sakai, Hitomi Izumi, Yukiko Matsushima, Noritaka Ichinohe, Yu-ichi Goto, Takashi Okada, and Ken Inoue
    • Organizer
      日本神経科学学会 第42回日本神経科学大会
    • Data Source
      KAKENHI-PROJECT-19K08358
  • [Presentation] Development of AAV enabling oligodendrocyte-specific gene suppression: implication for the treatment of Pelizaeus-Merzbacher disease2018

    • Author(s)
      Heng Li, Hironori Okada, Sadafumi Suzuki, Kazuhisa Sakai, Takashi Okada, Noritaka Ichinohe, Yu-ichi Goto, Ken Inoue
    • Organizer
      第41回日本分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-16K19679
  • [Presentation] Globally Impaired ER-Golgi trafficking as a cellular pathogenesis of Pelizaeus-Merzbacher Disease2017

    • Author(s)
      李コウ
    • Organizer
      第69回日本細胞生物学会大会
    • Data Source
      KAKENHI-PROJECT-16K19679
  • [Presentation] ER-Golgi transport may serve as a novel drug target for Pelizaeus-Merzbacher disease caused by PLP1 amino acid substitutions2016

    • Author(s)
      Ken Inoue, Heng Li, P.R. Mangalika, Yu-ichi Goto
    • Organizer
      第13回国際人類遺伝学会
    • Place of Presentation
      国立京都国際会館, 京都, 日本
    • Year and Date
      2016-04-03
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19679
  • [Presentation] Impaired ER-Golgi trafficking as a novel therapeutic target for Pelizaeus-Merzbacher disease caused by PLP1 amino acid substitutions.2016

    • Author(s)
      Ken Inoue, Heng Li, P.R. Mangalika, Yu-ichiGoto
    • Organizer
      The American Society of Human Genetics Annual Meeting 2016
    • Place of Presentation
      The Vancouver Convention Center, Vancouver, Canada
    • Year and Date
      2016-10-18
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19679
  • [Presentation] 不安様行動におけるCCKA 、CCKB 受容体の異なる役割2013

    • Author(s)
      李 コウ,太田英伸,泉 仁美,松田芳樹,関 美佳,戸田宜子,秋山美沙紀,松島由紀子,加我牧子,稲垣真澄
    • Organizer
      神経科学会
    • Place of Presentation
      京都 国際会議場
    • Data Source
      KAKENHI-PROJECT-25461745
  • 1.  INAGAKI Masumi (70203198)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 2.  OHTA Hidenobu (80422103)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 3.  INOUE Ken (30392418)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 4.  SAKAI Hiromi (70318830)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  KAGA Makiko (20142250)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  OSAKABE Hitomi (30625520)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  SUGIURA Yuka (50750402)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 8.  高梨 潤一
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

URL: 

Are you sure that you want to link your ORCID iD to your KAKEN Researcher profile?
* This action can be performed only by the researcher himself/herself who is listed on the KAKEN Researcher’s page. Are you sure that this KAKEN Researcher’s page is your page?

この研究者とORCID iDの連携を行いますか?
※ この処理は、研究者本人だけが実行できます。

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi