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MATSUSHITA MICHIKO  松下 倫子

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Matsushita Michiko  松下 倫子

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Researcher Number 70642198
Other IDs
Affiliation (Current) 2025: 鳥取大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2021 – 2024: 鳥取大学, 医学部, 助教
2014 – 2019: 鳥取大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 49020:Human pathology-related / Human pathology
Keywords
Principal Investigator
メルケル細胞癌 / メルケル細胞ポリオーマウイルス / MCPyV / 三次リンパ組織様構造 (TLS) / RNA修飾 / METTL3 / RNA-seq / 遺伝子病理診断学 / エピゲノム / Notch … More / H3K27me3 / SWI/SNF複合体 / NGS / immunohistochemistry / JAK-STAT経路 / Hedgehog signal経路 / CADM1 / Immunohistochemistry Less
  • Research Projects

    (4 results)
  • Research Products

    (22 results)
  • Co-Researchers

    (4 People)
  •  メルケル細胞癌の疲弊T細胞とTLS構成細胞に基づく治療効果予測・耐性機構の解明Principal Investigator

    • Principal Investigator
      松下 倫子
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Tottori University
  •  エピトランスクリプトーム解析によるメルケル細胞癌の病態機構解明Principal Investigator

    • Principal Investigator
      松下 倫子
    • Project Period (FY)
      2021 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49020:Human pathology-related
    • Research Institution
      Tottori University
  •  Analysis of epigenomic abnormalities in Merkel cell carcinomaPrincipal Investigator

    • Principal Investigator
      MATSUSHITA Michiko
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      Tottori University
  •  Analysis of pathogenesis using NGS in Merkel cell carcinoma associated polyomavirusPrincipal Investigator

    • Principal Investigator
      Matsushita Michiko
    • Project Period (FY)
      2014 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Human pathology
    • Research Institution
      Tottori University

All 2023 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

  • [Journal Article] Clinical significance of the expression of FOXP3 and TIGIT in Merkel cell carcinoma2023

    • Author(s)
      Iwasaki Takeshi、Hayashi Kazuhiko、Matsushita Michiko、Nonaka Daisuke、Matsumoto Takamasa、Taniguchi Midori、Kuwamoto Satoshi、Umekita Yoshihisa、Oda Yoshinao
    • Journal Title

      Scientific Reports

      Volume: 13 Issue: 1 Pages: 13114-13114

    • DOI

      10.1038/s41598-023-40050-7

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K15406, KAKENHI-PROJECT-21K06885
  • [Journal Article] Decreased H3K27me3 Expression is Associated With Merkel Cell Polyomavirus-Negative Merkel Cell Carcinoma, Especially Combined With Cutaneous Squamous Cell Carcinoma2019

    • Author(s)
      Michiko Matsushita, Takeshi Iwasaki, Lusi Oka Wardhani, Satoshi Kuwamoto, Daisuke Nonaka, Keiko Nagata, Masako Kato , Yukisato Kitamura , Kazuhiko Hayashi
    • Journal Title

      Anticancer Res.

      Volume: 39 Issue: 10 Pages: 5573-5579

    • DOI

      10.21873/anticanres.13751

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K08720, KAKENHI-PROJECT-17K15644
  • [Journal Article] Expression of Notch 3 and Jagged 1 Is Associated With Merkel Cell Polyomavirus Status and Prognosis in Merkel Cell Carcinoma.2019

    • Author(s)
      Wardhani LO, Matsushita M, Kuwamoto S, Nonaka D, Nagata K, Kato M, Kitamura Y, Hayashi K
    • Journal Title

      Anticancer Research

      Volume: 39 Issue: 1 Pages: 319-329

    • DOI

      10.21873/anticanres.13114

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15644, KAKENHI-PROJECT-17K08720
  • [Journal Article] Lower expression of CADM1 and higher expression of MAL in Merkel cell carcinomas are associated with Merkel cell polyomavirus infection and better prognosis.2016

    • Author(s)
      Iwasaki T, Matsushita M, Nonaka D, Nagata K, Kato M, Kuwamoto S, Murakami I, Hayashi K
    • Journal Title

      Hum Pathol.

      Volume: 48 Pages: 1-8

    • DOI

      10.1016/j.humpath.2015.09.030

    • Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460433, KAKENHI-PROJECT-26860238
  • [Journal Article] Comment on 'Cytokeratin 20-negative Merkel cell carcinoma is infrequently associated with the Merkel cell polyomavirus'.2016

    • Author(s)
      Iwasaki T, Matsushita M, Nonaka D, Murakami I, Hayashi K.
    • Journal Title

      Mod Pathol.

      Volume: 29 Issue: 1 Pages: 89-90

    • DOI

      10.1038/modpathol.2015.69

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26460433, KAKENHI-PROJECT-26860238
  • [Journal Article] A new in situ hybridization and immunohistochemistry with a novel antibody to detect small T-antigen expressions of Merkel cell polyomavirus (MCPyV).2014

    • Author(s)
      Matsushita M, Nonaka D, Iwasaki T, Kuwamoto S, Murakami I, Kato M, Nagata K, Kitamura Y, Hayashi K.
    • Journal Title

      Diagn Pathol

      Volume: 9 Issue: 1 Pages: 65-65

    • DOI

      10.1186/1746-1596-9-65

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24500420, KAKENHI-PROJECT-26460433, KAKENHI-PROJECT-26860238
  • [Presentation] RNAscopeを用いたメルケル細胞癌の組織切片上でのMCPyV検出の有用性2023

    • Author(s)
      松下 倫子, 林 一彦, 岩崎 健, 桑本 聡史
    • Organizer
      第112回 日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06885
  • [Presentation] RNAscopeを用いたメルケル細胞癌の組織切片上でのMCPyV検出の有用性2023

    • Author(s)
      松下倫子、林一彦、岩崎健、桑本聡史
    • Organizer
      第112回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06885
  • [Presentation] メルケル細胞癌におけるFOXP3、TIGIT/CD155経路の異常発現と臨床病態の解明2023

    • Author(s)
      岩崎 健, 林 一彦, 松下 倫子, 松本 崇雅, 宮本 拓海, 大石 智恵美, 桑本 聡史, 梅北 善久, 小田 義直
    • Organizer
      第112回 日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-21K06885
  • [Presentation] The expression of Notch signaling pathway in Merkel cell carcinoma.2019

    • Author(s)
      Matsushita M, Lusi Oka Wardhani, Iwasaki T, Kuwamoto S, Nonaka D, Nagata K, Kato M, Kitamura Y, Hayashi K
    • Organizer
      31st European Congress of Pathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15644
  • [Presentation] メルケル細胞ポリオーマウイルス陰性のメルケル細胞癌では、ヒストンH3K27me3修飾が低下する2018

    • Author(s)
      松下倫子、岩崎健、桑本聡史、野中大輔、長田佳子、加藤雅子、北村幸郷、林一彦
    • Organizer
      第107回日本病理学会総会
    • Data Source
      KAKENHI-PROJECT-17K15644
  • [Presentation] The histone modification H3K27me3 is reduced in MCPyV-negative Merkel cell carcinomas.2018

    • Author(s)
      Matsushita M, Iwasaki T, Kuwamoto S, Lusi Oka Wardhani, Nonaka D, Nagata K, Kato M, Kitamura Y, Hayashi K.
    • Organizer
      30th European Congress of Pathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15644
  • [Presentation] Altered expression of SWI/SNF complex and its significance in Merkel cell carcinoma.2017

    • Author(s)
      Matsushita M, et al.
    • Organizer
      29th European Congress of Pathology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K15644
  • [Presentation] メルケル細胞癌におけるJAK-STAT経路活性化とMCPyVおよび予後との関係2016

    • Author(s)
      松下倫子、岩崎健、野中大輔、桑本聡史、長田佳子、加藤雅子、北村幸郷、林一彦
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター(宮城)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] メルケル細胞癌におけるHedgehog signal発現とMCPyV感染および予後との関連2016

    • Author(s)
      黒見晃行、松下倫子、岩崎健、野中大輔、桑本聡史、長田佳子、加藤雅子、北村幸郷、林一彦
    • Organizer
      第105回日本病理学会総会
    • Place of Presentation
      仙台国際センター(宮城)
    • Year and Date
      2016-05-12
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] Ecology of merkel cell polyomavirus in healthy skin among individuals in an asian cohort shows close agreement with interleukin-1 loop model in langerhans cell histiocytosis.2016

    • Author(s)
      Murakami I, Nakashima J, Hashida Y, Daibata M, Matsushita M, Iwasaki T, Kuwamoto S, Kato M, Nagata K, Hayashi K, Oka T, Yoshino T, Imamura T, Morimoto A, Imashuku S, Gogusev J, Jaubert F.
    • Organizer
      32nd Annual Meeting of the Histiocyte Society
    • Place of Presentation
      Dublin (Ireland)
    • Year and Date
      2016-10-17
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] The relations of JAK-STAT signaling expressions to MCPyV-infection and outcome in Merkel cell carcinomas.2016

    • Author(s)
      Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Kato M, Kitamura Y, Hayash K.
    • Organizer
      XXXI International Congress of the International Academy of Pathology and 28th Congress of the European Society of Pathology
    • Place of Presentation
      Cologne (Germany)
    • Year and Date
      2016-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] Expression of a long non-coding RNA NEAT1 is significantly higher in MCPyV-positive Merkel cell carcinomas than MCPyV-negative ones.2016

    • Author(s)
      Akizuki G, Imamura K, Yamada T, Mizutani R, Matsushita M, Iwasaki T, Nonaka D, Kuwamoto S, Nagata K, Hayashi K, Akimitsu N.
    • Organizer
      XXXI International Congress of the International Academy of Pathology and 28th Congress of the European Society of Pathology
    • Place of Presentation
      Cologne (Germany)
    • Year and Date
      2016-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] Biphasic production of immunoglobulin from Epstein-Barr virus reactivated lymphocytes in Graves' disease patients and controls.2016

    • Author(s)
      Nagata K, Kumata K, Nakayama Y, Satoh Y, Matsushita M, Kuwamoto S, Kato M, Sugihara H, Murakami I, Hayashi K.
    • Organizer
      XXXI International Congress of the International Academy of Pathology and 28th Congress of the European Society of Pathology
    • Place of Presentation
      Cologne (Germany)
    • Year and Date
      2016-09-25
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] Activation-induced deaminase (AID) gene expressions in Merkel cell carcinomas.by immunohistochemical and molecular analysis2015

    • Author(s)
      Matsushita M, et al.
    • Organizer
      27th European Congress of Pathology
    • Place of Presentation
      Belgrade (Serbia)
    • Year and Date
      2015-09-08
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] メルケル細胞癌の発癌における活性化誘導シチジンデアミナーゼ発現関与の検討2015

    • Author(s)
      松下倫子、他
    • Organizer
      第104回日本病理学会総会
    • Place of Presentation
      名古屋国際会議場(愛知)
    • Year and Date
      2015-04-30
    • Data Source
      KAKENHI-PROJECT-26860238
  • [Presentation] Higher CADM1 expression and lower MAL expression in Merkel cell carcinomas (MCCs) are associated with MCPyV-negative MCCs and unfavorable outcome.

    • Author(s)
      Iwasaki T, Matsushita M, et al.
    • Organizer
      27th European Congress of Pathology
    • Place of Presentation
      Belgrade (Serbia)
    • Year and Date
      2015-09-05 – 2015-09-09
    • Data Source
      KAKENHI-PROJECT-26860238
  • 1.  林 一彦 (30180962)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  岩崎 健 (40766185)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  KATO Shinsuke
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 4.  加藤 雅子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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