Fukuda Akihisa 福田晃久

Researcher Number	70644897
Other IDs	https://orcid.org/0000-0002-1940-596X
Affiliation (Current)	2025: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2024: 京都大学, 医学研究科, 講師 2019 – 2022: 京都大学, 医学研究科, 講師 2016 – 2018: 京都大学, 医学研究科, 特定病院助教 2016: 京都大学, 大学院医学研究科, 助教 2014 – 2015: 京都大学, 医学(系)研究科(研究院), 助教 2013: 京都大学, 医学(系)研究科(研究院), 医員
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Gastroenterology Except Principal Investigator Gastroenterology
Keywords	Principal Investigator 膵癌 / クロマチンリモデリング / マウスモデル / エピジェネティクス / 膵がん / IPMN / 浸潤 / 転移 / 治療 / 治療標的 … More / クロマチンリモデリング因子 / 分子機序 / 膵臓学 / 胆道学 / マウス / 起源細胞 / エピゲネティクス / 膵臓癌 / 膵臓がん … More Except Principal Investigator 癌 / 内科 / 分化 / 可塑性 / 膵臓癌 / 大腸癌 / 胃 / 膵臓 / 大腸 / 消化器 / 幹細胞 Less

ヒト膵癌の転移、進行におけるRECKの機能的役割の解明Principal Investigator
- Principal Investigator
  
  福田晃久
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyoto University
The functional role of chromatin regulator in established PDACPrincipal Investigator
- Principal Investigator
  
  Fukuda Akihisa
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kyoto University
Therapeutic strategy against gastrointestinal cancer by utilizing cancer hierarchy
- Principal Investigator
  
  Seno Hiroshi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
The functional role of chromatin remodeling regualtor Arid11a in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Fukuda Akihisa
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
Anti-cancer therapies baesd on novel cancer stem cell-specific factors
- Principal Investigator
  
  Seno Hiroshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University
The functional role of chromatin remodeling regualtor Brg1 in pancreatic cancerPrincipal Investigator
- Principal Investigator
  
  Fukuda Akihisa
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Gastroenterology
- Research Institution
  Kyoto University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras.2023
- Author(s)
  Munemasa Nagao, Kenta Mizukoshi, Shinnosuke Nakayama, Mio Namikawa, Yukiko Hiramatsu, Takahisa Maruno, Yuki Nakanishi, Tatsuaki Tsuruyama, Akihisa Fukuda*, Hiroshi Seno. *corresponding author
- Journal Title
  
  Oncotarget
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03639
[Journal Article] Impact of neoadjuvant intensity-modulated radiation therapy on borderline resectable pancreatic cancer with arterial abutment; a prospective, open-label, phase II study in a single institution.2022
- Author(s)
  Masui T, Nagai K, Anazawa T, Sato A, Uchida Y, Nakano K, Yogo A, Kaneda A, Nakamura N, Yoshimura M, Mizowaki T, Uza N, Fukuda A, Matsumoto S, Kanai M, Isoda H, Mizumoto M, Seo S, Hata K, Taura K, Kawaguchi Y, Takaori K, Uemoto S, Hatano E.
- Journal Title
  
  BMC Cancer
  
  Volume: 29 Issue: 1 Pages: 119-119
- DOI
  10.1186/s12885-022-09244-6
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03639
[Journal Article] Context-Dependent Roles of Hes1 in the Adult Pancreas and Pancreatic Tumor Formation.2022
- Author(s)
  Marui S, Nishikawa Y, Shiokawa M, Yokode M, Matsumoto S, Muramoto Y, Ota S, Nakamura T, Yoshida H, Okada H, Kuwada T, Matsumori T, Kuriyama K, Fukuda A, Saur D, Aoi T, Uza N, Kodama Y, Chiba T, Seno H.
- Journal Title
  
  Gastroenterology.
  
  Volume: 163 Issue: 6 Pages: 1613-1629
- DOI
  10.1053/j.gastro.2022.08.048
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19480, KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-20J01362
[Journal Article] <scp>JNK</scp> pathway plays a critical role for expansion of human colorectal cancer in the context of <scp>BRG1</scp> suppression2022
- Author(s)
  Yoshikawa Takaaki、Fukuda Akihisa、Omatsu Mayuki、Namikawa Mio、Sono Makoto、Fukunaga Yuichi、Masuda Tomonori、Araki Osamu、Nagao Munemasa、Ogawa Satoshi、Masuo Kenji、Goto Norihiro、Hiramatsu Yukiko、Muta Yu、Tsuda Motoyuki、Maruno Takahisa、Nakanishi Yuki、Kawada Kenji、Takaishi Shigeo、Seno Hiroshi
- Journal Title
  
  Cancer Science
  
  Volume: 113 Issue: 10 Pages: 3417-3427
- DOI
  10.1111/cas.15520
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15948, KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-22KJ2232, KAKENHI-PROJECT-23K21432
[Journal Article] Loss of Arid1a and Pten in Pancreatic Ductal Cells Induces Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway.2022
- Author(s)
  Fukunaga Y, Fukuda A, Omatsu M, Namikawa M, Sono M, Masuda T, Araki O, Nagao M, Yoshikawa T, Ogawa S, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Ferrer J, Tsuruyama T, Masui T, Hatano E, Seno H.
- Journal Title
  
  Gastroenterology.
  
  Volume: 163 Issue: 2 Pages: 466-480
- DOI
  10.1053/j.gastro.2022.04.020
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K19480, KAKENHI-PROJECT-21K15948, KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-22KJ2232, KAKENHI-PROJECT-23K21432
[Journal Article] Concurrent activation of Kras and canonical Wnt signaling induces premalignant lesions that progress to extrahepatic biliary cancer in mice2022
- Author(s)
  Nagao M, Fukuda A, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Yoshikawa T, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Taketo MM, Ferrer J, Tsuruyama T, Nakanuma Y, Taura K, Uemoto S, Seno H.
- Journal Title
  
  Cancer Res.
  
  Volume: - Issue: 9 Pages: 1803-1817
- DOI
  10.1158/0008-5472.can-21-2176
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22841, KAKENHI-PROJECT-19J01318, KAKENHI-PROJECT-21K20801, KAKENHI-PROJECT-22KJ2232, KAKENHI-PROJECT-21K19480, KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-23K21432
[Journal Article] SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP22021
- Author(s)
  Masuo K, Chen R, Yogo A, Sugiyama A, Fukuda A, Masui T, Uemoto S, Seno H, Takaishi S.
- Journal Title
  
  Cancer Sci.
  
  Volume: 112 Issue: 12 Pages: 4987-4999
- DOI
  10.1111/cas.15162
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-21K19480, KAKENHI-PROJECT-19H03639
[Journal Article] Brg1 is required to maintain colorectal cancer stem cells.2021
- Author(s)
  Yoshikawa T, Fukuda A*, Omatsu M, Namikawa M, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Muta Y, Tsuda M, Maruno T, Nakanishi Y, Kawada K, Takaishi S, Seno H.
- Journal Title
  
  J Pathology
  
  Volume: 255 Pages: 257-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19H03639
[Journal Article] Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging2021
- Author(s)
  Maruno Takahisa、Fukuda Akihisa、Goto Norihiro、Tsuda Motoyuki、Ikuta Kozo、Hiramatsu Yukiko、Ogawa Satoshi、Nakanishi Yuki、Yamaga Yuichi、Yoshioka Takuto、Takaori Kyoichi、Uemoto Shinji、Saur Dieter、Chiba Tsutomu、Seno Hiroshi
- Journal Title
  
  eLife
  
  Volume: 10 Pages: 1-24
- DOI
  10.7554/elife.55117
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K22841, KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-18J01600, KAKENHI-PROJECT-19K22619, KAKENHI-PROJECT-19K16712
[Journal Article] The role of SWI/SNF chromatin remodeling complex in pancreatic cancer. *corresponding author2021
- Author(s)
  2.Motoyuki Tsuda, Akihisa Fukuda, Munenori Kawai, Osamu Araki, Hiroshi Seno.
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 2 Pages: 490-497
- DOI
  10.1111/cas.14768
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-19J01318, KAKENHI-PROJECT-19K22619
[Journal Article] Setdb1 inhibits p53-mediated apoptosis and is required for formation of pancreatic ductal adenocarcinomas in mice.2020
- Author(s)
  6.Ogawa S, Fukuda A, Matsumoto Y, Hanyu Yu, Sono M, Fukunaga Y, Masuda T, Araki O, Nagao M, Yoshikawa T, Goto N, Hiramatsu Y, Tsuda M, Maruno T, Nakanishii Y, Hussein S.M, Tsuruyama T, Takaori K, Uemotoio　S, Seno H.
- Journal Title
  
  Gastroenterology
  
  Volume: 159 Issue: 2 Pages: 682-696
- DOI
  10.1053/j.gastro.2020.04.047
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03639, KAKENHI-PROJECT-20H03659, KAKENHI-PROJECT-18J01600, KAKENHI-PROJECT-19K22619
[Journal Article] Arid1a is essential for intestinal stem cells through Sox9 regulation.2019
- Author(s)
  Hiramatsu Y, Fukuda A, Ogawa S, Goto N, Ikuta K, Tsuda M, Matsumoto Y, Kimura Y, Yoshioka T, Takada Y, Maruno T, Hanyu Y, Tsuruyama T, Wang Z, Akiyama H, Takaishi S, Miyoshi H, Taketo MM, Chiba T, Seno H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 116 (5) Issue: 5 Pages: 1704-1713
- DOI
  10.1073/pnas.1804858116
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09460, KAKENHI-PROJECT-15H05721, KAKENHI-PROJECT-17H04059, KAKENHI-PROJECT-17H04157
[Journal Article] Bmi1 marks gastric stem cells located in the isthmus in mice.2019
- Author(s)
  Yoshioka T, Fukuda A, Araki O, Ogawa S, Hanyu Y, Matsumoto Y, Yamaga Y, Nakanishi Y, Kawada K, Sakai Y, Chiba T, Seno H.
- Journal Title
  
  J Pathol.
  
  Volume: 248 Issue: 2 Pages: 179-190
- DOI
  10.1002/path.5244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22619, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-17H04157
[Journal Article] Epithelial EP4 plays an essential role in maintaining homeostasis in colon.2019
- Author(s)
  Matsumoto Y, Nakanishi Y, Yoshioka T, Yamaga Y, Masuda T, Fukunaga Y, Sono M, Yoshikawa T, Nagao M, Araki O, Ogawa S, Goto N, Hiramatsu Y, Breyer RM, Fukuda A, Seno H.
- Journal Title
  
  Sci Rep.
  
  Volume: 9 Issue: 1 Pages: 15244-15244
- DOI
  10.1038/s41598-019-51639-2
- NAID
  120006956728
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22619, KAKENHI-PROJECT-19K16712, KAKENHI-PROJECT-17H04157
[Journal Article] Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells.2019
- Author(s)
  Goto N, Fukuda A, Yamaga Y, Yoshikawa T, Maruno T, Maekawa H, Inamoto S, Kawada K, Sakai Y, Miyoshi H, Taketo MM, Chiba T, Seno H.
- Journal Title
  
  Proc Natl Acad Sci U S A.
  
  Volume: 116 Issue: 26 Pages: 12996-13005
- DOI
  10.1073/pnas.1900251116
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22619, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-18J01600
[Journal Article] ARID1A Maintains Differentiation of Pancreatic Ductal Cells and inhibits Development of Pancreatic Ductal Adenocarcinoma in Mice2018
- Author(s)
  Yoshito Kimura, Akihisa Fukuda, Satoshi Ogawa, Takahisa Maruno, Yutaka Takada, Motoyuki Tsuda, Yukiko Hiramatsu, Osamu Araki, Munemasa Nagao, Takaaki Yoshikawa, Kozo Ikuta, Takuto Yoshioka, Zong Wang, Haruhiko Akiyama, Christopher V. Wright, Kyoichi Takaori, Shinji Uemoto, Tsutomu Chiba, Hiroshi Seno
- Journal Title
  
  Gastroenterology
  
  Volume: 3 Issue: 1 Pages: 30346-9
- DOI
  10.1053/j.gastro.2018.03.039
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09394, KAKENHI-PROJECT-17J05511, KAKENHI-PROJECT-17H04157
[Journal Article] The BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.2018
- Author(s)
  Tsuda M, Fukuda A, Roy N, Hiramatsu Y, Leonhardt L, Kakiuchi N, Hoyer K, Ogawa S, Goto N, Ikuta K, Kimura Y, Matsumoto Y, Takada Y, Yoshioka T, Maruno T, Yamaga Y, Kim GE, Akiyama H, Ogawa S, Wright CV, Saur D, Takaori K, Uemoto S, Hebrok M, Chiba T, Seno H.
- Journal Title
  
  J Clin Invest.
  
  Volume: 128 Issue: 8 Pages: 3475-3489
- DOI
  10.1172/jci94287
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-17H06805, KAKENHI-PROJECT-16K09394, KAKENHI-PROJECT-16K15613
[Journal Article] Nardilysin inhibits pancreatitis and suppresses pancreatic ductal adenocarcinoma initiation in mice.2018
- Author(s)
  Ikuta K, Fukuda A, Ogawa S, Masuo K, Goto N, Hiramatsu Y, Tsuda M, Kimura Y, Matsumoto Y, Kimura Y, Maruno T, Kanda K, Nishi K, Takaori K, Uemoto S, Takaishi S, Chiba T, Nishi E, Seno H.
- Journal Title
  
  Gut
  
  Volume: 印刷中 Issue: 5 Pages: 882-892
- DOI
  10.1136/gutjnl-2017-315425
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09460, KAKENHI-PUBLICLY-18H04694, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-17H06804, KAKENHI-PROJECT-16K09394, KAKENHI-PROJECT-16K15613
[Journal Article] Nardilysin controls intestinal tumorigenesis through HDAC1/p53?dependent transcriptional regulation2018
- Author(s)
  Kanda Keitaro、Sakamoto Jiro、Matsumoto Yoshihide、Ikuta Kozo、Goto Norihiro、Morita Yusuke、Ohno Mikiko、Nishi Kiyoto、Chiba Tsutomu、Nishi Eiichiro、Seno Hiroshi
- Journal Title
  
  JCI Insight
  
  Volume: 3 Issue: 8 Pages: 1-15
- DOI
  10.1172/jci.insight.91316
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09575, KAKENHI-PROJECT-16H05297, KAKENHI-PROJECT-17H04048, KAKENHI-PROJECT-15J03212, KAKENHI-PROJECT-16K15216, KAKENHI-PLANNED-18H05503, KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-18H04164
[Journal Article] Gene expression profile of Dclk1+ cells in intestinal tumors.2018
- Author(s)
  Yamaga Y, Fukuda A, Nakanishi Y, Goto N, Matsumoto Y, Yoshioka T, Maruno T, Chiba T, Seno H.
- Journal Title
  
  Dig Liver Dis.
  
  Volume: 50 Issue: 12 Pages: 1353-1361
- DOI
  10.1016/j.dld.2018.06.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H04157
[Journal Article] Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine2017
- Author(s)
  Goto Norihiro、Ueo Taro、Fukuda Akihisa、Kawada Kenji、Sakai Yoshiharu、Miyoshi Hiroyuki、Taketo Makoto Mark、Chiba Tsutomu、Seno Hiroshi
- Journal Title
  
  Cancer Research
  
  Volume: 77 Issue: 13 Pages: 3442-3454
- DOI
  10.1158/0008-5472.can-16-3192
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04157, KAKENHI-PROJECT-15J03212, KAKENHI-PROJECT-16K15427
[Journal Article] Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling.2016
- Author(s)
  Takada Y, Fukuda A, Chiba T, Seno H.
- Journal Title
  
  Development
  
  Volume: 143 Pages: 3532-3539
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26293173
[Journal Article] Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling2016
- Author(s)
  Takada Y, Fukuda A, Chiba T, Seno H.
- Journal Title
  
  Development
  
  Volume: 143 Issue: 19 Pages: 3532-3539
- DOI
  10.1242/dev.141549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09394
[Journal Article] Molecular Mechanism of Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN-derived Pancreatic Ductal Adenocarcinoma2015
- Author(s)
  Fukuda A
- Journal Title
  
  J Hepatobiliary Pancreatic Sci
  
  Volume: ２２ Pages: 519-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461021
[Journal Article] Molecular mechanism of Intraductal Papillary Mucinous Neoplasm (IPMN) and IPMN-derived Pancreatic Ductal Adenocarcinoma.2015
- Author(s)
  Fukuda, A
- Journal Title
  
  J Hepatobiliary Pancreatic Sci
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461021
[Journal Article] EP4 receptor–associated protein in macrophages ameliorates colitis and colitis-associated tumorigenesis.2015
- Author(s)
  Nakatsuji, M., M. Minami*, H. Seno*, M. Yasui, H. Komekado, S. Higuchi, R. Fujikawa, Y. Nakanishi, A. Fukuda, K. Kawada, Y. Sakai, T. Kita, P. Libby, H. Ikeuchi, M. Yokode, and T. Chiba
- Journal Title
  
  PLoS Genet
  
  Volume: 11 Issue: 10 Pages: e1005542-e1005542
- DOI
  10.1371/journal.pgen.1005542
- NAID
  120005947032
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K08230, KAKENHI-PROJECT-26460338, KAKENHI-PROJECT-26293173
[Journal Article] The Chromatin Regulator Brg1 Suppresses Formation of Intraductal Papillary Mucinous Neoplasm and Pancreatic Ductal Adenocarcinoma.2014
- Author(s)
  von Figura G*, Fukuda A*, Roy N* Roy N*, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J,Mueller WF, Busch A, Hertel KJ, Hebrok M. co-first authors
- Journal Title
  
  Nature Cell Biology
  
  Volume: 16 Issue: 3 Pages: 255-267
- DOI
  10.1038/ncb2916
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461021
[Journal Article] Brg1はIPMNおよびIPMN由来膵癌の形成を抑制する2014
- Author(s)
  福田晃久
- Journal Title
  
  分子消化器病
  
  Volume: 12
- Data Source
  KAKENHI-PROJECT-25461021
[Presentation] Simultaneous loss of Arid1a and Pten in pancreatic ductal cells induces ITPN and PDAC through activation of the YAP/TAZ pathway.2022
- Author(s)
  福田晃久
- Organizer
  ムーンショットワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03639
[Presentation] The role of chromatin remodeling regulators in pancreatic cancer.2022
- Author(s)
  Akihisa Fukuda
- Organizer
  The 7th JCA-AACR Special Joint Conference
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03639
[Presentation] 膵がんの上皮間葉転換・転移の制御因子2022
- Author(s)
  福田晃久、妹尾浩.
- Organizer
  第3回「医学と数理」ワークショップ
- Invited
- Data Source
  KAKENHI-PROJECT-19H03639
[Presentation] Insights into initiation and progression of PDAC.2022
- Author(s)
  Akihisa Fukuda
- Organizer
  American Pancreatic Association Annual meeting
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03639
[Presentation] クロマチン制御因子を標的とした新規膵がん治療法の開発.2022
- Author(s)
  福田晃久
- Organizer
  京都大学「医学領域」産学連携推進機構／一般社団法人芝蘭会産学情報交流会セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-19H03639
[Presentation] The mechanism of pancreatic cancer development.2021
- Author(s)
  Akihisa Fukuda
- Organizer
  The 5th Annual conference of Al-Azhar Hepatogastroenterology club (AHC, 2021), Therapeutic advances in hepatogastroenterology.
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03639
[Presentation] The role of tuft cell-like tumor/cancer cells in intestinal tumors.2019
- Author(s)
  妹尾浩、後藤規弘、福田晃久
- Organizer
  第78回日本癌学会総会
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] BRG1/SOX9 axis is critical for acinar cell-derived pancreatic tumorigenesis.2018
- Author(s)
  津田喬之、福田晃久、妹尾浩
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] The functional role of Eset in exocrine pancreatic regeneration and pancreatic cancer initiation2018
- Author(s)
  小川智、福田晃久、津田喬之、後藤規弘、平松由紀子、妹尾浩
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] Sox9制御を介した腸幹細胞、腸恒常性維持におけるArid1aの役割について2018
- Author(s)
  平松由紀子、福田晃久、妹尾浩
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] Essential role of Arid1a in intestinal stem cell maintenance and homeostasis through Sox9 regulation.2018
- Author(s)
  Yukio Hiramatsu, Akihisa Fukuda, Hiroshi Seno
- Organizer
  GI Research Academy 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] 腸管の正常幹細胞と腫瘍幹細胞におけるHes1の役割2018
- Author(s)
  後藤規弘、福田晃久、妹尾浩
- Organizer
  第104回日本消化器病学会総会
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] 膵がん形成過程における可塑性と幹細胞性2017
- Author(s)
  妹尾浩、丸野貴久、後藤規弘、津田喬之、木村佳人、福田晃久
- Organizer
  第76回日本癌学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] Brg1 plays a critical role in PanIN formation through regulating Sox9 expression.2017
- Author(s)
  Motoyuki Tsuda, Akihisa Fukuda, Takahisa Maruno, Haruhiko Akiyama, Kyoichi Takaori, Shinji Uemoto, Tsutomu Chiba, Hiroshi Seno, et al.
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] The role of Hes1 in the normal and tumor stem cells of the intestine.2017
- Author(s)
  Norihiro Goto, Akihisa Fukuda, Tsutomu Chiba, Hiroshi Seno
- Organizer
  American Association for Cancer Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] Nardilysin functions as a tumor suppressor in pancreatic ductal adenocarcinoma through maintaining acinar cell differentiation and suppressing pancreatitis.2017
- Author(s)
  Kozo Ikuta, Akihisa Fukuda, Eiichiro Nishi, Hiroshi Seno, et al.
- Organizer
  Digestive Disease Week 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H04157
[Presentation] クロマチンリモデリング因子Ｂrg１はIＰＭＮおよびIPMN由来膵癌の発生を抑制する2016
- Author(s)
  Fukuda A, Chiba T, Seno H
- Organizer
  第20回分子標的治療学会学術集会
- Place of Presentation
  別府
- Year and Date
  2016-05-31
- Invited
- Data Source
  KAKENHI-PROJECT-25461021
[Presentation] 消化器腫瘍における腫瘍幹細胞標的治療2016
- Author(s)
  妹尾浩、丸野貴久、後藤規弘、福田晃久
- Organizer
  第75回日本癌学会総会
- Place of Presentation
  横浜市　パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-26293173
[Presentation] Hierarchy in mouse digestive organ tumors.2016
- Author(s)
  妹尾浩、丸野貴久、津田喬之、福田晃久
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  横浜市　パシフィコ横浜
- Invited
- Data Source
  KAKENHI-PROJECT-26293173
[Presentation] Role of Dclk1-expressing cells in digestive organs.2016
- Author(s)
  Seno H, Maruno T, Fukuda A.
- Organizer
  The 41st Naito Conference
- Place of Presentation
  Sapporo, Chateraise Gateaux Kingdom
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293173
[Presentation] Targeting tumor stem cells in the intestine.2015
- Author(s)
  Seno H, Yamaga Y, Matsumoto Y, Nakanishi Y, Fukuda A, Chiba T.
- Organizer
  The 3rd JSGE International Topic Conference
- Place of Presentation
  仙台市
- Year and Date
  2015-04-25
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26293173
[Presentation] Cell of origin and complexity in digestive organ tumors.2015
- Author(s)
  妹尾浩、福田晃久、丸野貴久、後藤規弘、千葉勉
- Organizer
  第74回日本癌学会学術総会
- Place of Presentation
  名古屋市
- Year and Date
  2015-10-08
- Invited
- Data Source
  KAKENHI-PROJECT-26293173
[Presentation] 膵臓癌の発生におけるクロマチンリモデリング因子Brg1の役割
- Author(s)
  Fukuda A*, von Figura G*, Roy N*, Liku ME, Morris Iv JP, Kim GE, Russ HA, Firpo MA, Mulvihill SJ, Dawson DW, Ferrer J, Mueller WF, Busch A, Hertel KJ, Hebrok M. * Equal Atuthorship
- Organizer
  日本分子生物学会
- Place of Presentation
  神戸ポートピアホテル（神戸)
- Invited
- Data Source
  KAKENHI-PROJECT-25461021
[Presentation] Identification of a pancreatic tumor specific stem cell marker.
- Author(s)
  Takahisa Maruno, Akihisa Fukuda, Hiroshi Seno, Tsutomu　Chiba.
- Organizer
  第73回日本癌学会学術総会 2014　東京.
- Place of Presentation
  東京
- Year and Date
  2014-09-25 – 2014-09-27
- Data Source
  KAKENHI-PROJECT-25461021

1. SENO HIROSHI (90335266)

# of Collaborated Projects: 5 results

# of Collaborated Products: 32 results
2. MINAMI Manabu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 高石繁生

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
4. 大野美紀子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 横出正之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Fukuda Akihisa 福田 晃久

Research Projects

Research Products

Co-Researchers

ヒト膵癌の転移、進行におけるRECKの機能的役割の解明Principal Investigator

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The functional role of chromatin regulator in established PDACPrincipal Investigator

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Therapeutic strategy against gastrointestinal cancer by utilizing cancer hierarchy

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The functional role of chromatin remodeling regualtor Arid11a in pancreatic cancerPrincipal Investigator

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Anti-cancer therapies baesd on novel cancer stem cell-specific factors

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The functional role of chromatin remodeling regualtor Brg1 in pancreatic cancerPrincipal Investigator

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[Journal Article] p53 protects against formation of extrahepatic biliary precancerous lesions in the context of oncogenic Kras.2023

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[Journal Article] Impact of neoadjuvant intensity-modulated radiation therapy on borderline resectable pancreatic cancer with arterial abutment; a prospective, open-label, phase II study in a single institution.2022

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[Journal Article] Context-Dependent Roles of Hes1 in the Adult Pancreas and Pancreatic Tumor Formation.2022

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[Journal Article] <scp>JNK</scp> pathway plays a critical role for expansion of human colorectal cancer in the context of <scp>BRG1</scp> suppression2022

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[Journal Article] Loss of Arid1a and Pten in Pancreatic Ductal Cells Induces Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway.2022

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[Journal Article] Concurrent activation of Kras and canonical Wnt signaling induces premalignant lesions that progress to extrahepatic biliary cancer in mice2022

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[Journal Article] SNAIL2 contributes to tumorigenicity and chemotherapy resistance in pancreatic cancer by regulating IGFBP22021

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[Journal Article] Brg1 is required to maintain colorectal cancer stem cells.2021

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[Journal Article] Visualization of stem cell activity in pancreatic cancer expansion by direct lineage tracing with live imaging2021

Author(s)

Fukuda Akihisa 福田晃久