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Natsuga Ken  夏賀 健

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NATSUGA Ken  夏賀 健

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Researcher Number 70645457
Other IDs
External Links
Affiliation (Current) 2025: 北海道大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help 2021 – 2024: 北海道大学, 医学研究院, 准教授
2020 – 2021: 北海道大学, 大学病院, 講師
2016 – 2018: 北海道大学, 大学病院, 講師
2015: 北海道大学, 北海道大学病院, 助教
2013 – 2015: 北海道大学, 大学病院, 助教
Review Section/Research Field
Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related
Except Principal Investigator
Dermatology / Basic Section 53050:Dermatology-related
Keywords
Principal Investigator
表皮水疱症 / 再生医学 / 幹細胞 / 毛包 / 表皮 / 創傷治癒 / 細胞外マトリクス / 自己抗原 / 自己抗体
Except Principal Investigator
皮膚病態学 … More / 皮膚病態斈 / 免疫寛容 / 表皮水疱症 / 自己免疫性水疱症 / 17型コラーゲン / 水疱性類天疱瘡 / 皮膚病理学 / Age-associated B cell / 制御性T細胞 / 水疱症 / 免疫チェックポイント阻害薬 / DPP-4阻害薬 / 7型コラーゲン / BP180 / 類天疱瘡 / 加齢 / 自己免疫疾患 / 瘢痕型脱毛症 / 自己抗体 / コラーゲン / 細菌叢 / 皮膚基底膜 / 皮膚細菌叢 / COL17 / プラスミン / 自己免疫 / 酵素 / 細胞・組織 / タンパク質 / 生体分子 Less
  • Research Projects

    (14 results)
  • Research Products

    (109 results)
  • Co-Researchers

    (21 People)
  •  Identifying and overcoming factors contributing to delayed wound healing in epidermolysis bullosa.Principal Investigator

    • Principal Investigator
      夏賀 健
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Hokkaido University
  •  Elucidation of the mechanism of the breakdown of cutaneous immune tolerance focusing on aging

    • Principal Investigator
      Ujiie Hideyuki
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Hokkaido University
  •  エピトープスプレディング現象に着目した水疱性類天疱瘡の病態解明

    • Principal Investigator
      西江 渉
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 53050:Dermatology-related
    • Research Institution
      Hokkaido University
  •  Dynamics of epithelial stem cells upon woundingPrincipal Investigator

    • Principal Investigator
      Natsuga Ken
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Novel bullous pemphigoid models induced by breaking tolerance to autoantigens.

    • Principal Investigator
      Nishie Wataru
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Establishment of cicatricial alopecia animal models

    • Principal Investigator
      Nakamura Hideki
    • Project Period (FY)
      2016 – 2018
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Pathogenesis of bullous pemphigoid: a study using class-switched monoclonal antibodies.

    • Principal Investigator
      Nishie Wataru
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Treatment of epidermolysis bullosa with revertant keratinocyte-derived iPS cells

    • Principal Investigator
      Fujita Yasuyuki
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Prevention of autoantigen depletion for bullous pemphigoid treatmentPrincipal Investigator

    • Principal Investigator
      Natsuga Ken
    • Project Period (FY)
      2015 – 2016
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Induction of tolerance to bullous pemphigoid autoantigen by oral administration of antigenic peptides.

    • Principal Investigator
      Nishie Wataru
    • Project Period (FY)
      2015
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Generation of mosaic model of epidermolysis bullosa by inactivation of X chromosome.

    • Principal Investigator
      NISHIE Wataru
    • Project Period (FY)
      2014
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Elucidating roles of plasmin in blister formation of bullous pemphigoid

    • Principal Investigator
      Nakamura Hideki
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Modulation of skin microbiota through basememt membrane

    • Principal Investigator
      SHIMIZU Hiroshi
    • Project Period (FY)
      2013
    • Research Category
      Grant-in-Aid for Challenging Exploratory Research
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University
  •  Production of a novel blistering disease model by regulating expression of collagen XVII

    • Principal Investigator
      Nishie Wataru
    • Project Period (FY)
      2012 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Dermatology
    • Research Institution
      Hokkaido University

All 2023 2022 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

  • [Book] Current Genetics in Dermatology2013

    • Author(s)
      Natsuga K
    • Total Pages
      16
    • Publisher
      INTECH
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Book] Epidermolysis bullosa simplex Current Genetics in Dermatology2013

    • Author(s)
      Natsuga K
    • Publisher
      Intech
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Native Autoantigen Complex Detects Pemphigoid Autoantibodies2023

    • Author(s)
      Mai Shoko、Izumi Kentaro、Mai Yosuke、Natsuga Ken、Ishii Norito、Sawamura Daisuke、Schauer Franziska、Kiritsi Dimitra、Nishie Wataru、Ujiie Hideyuki
    • Journal Title

      JID Innovations

      Volume: 3 Issue: 3 Pages: 100193-100193

    • DOI

      10.1016/j.xjidi.2023.100193

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K17334, KAKENHI-PROJECT-22K08419, KAKENHI-PROJECT-21K08316, KAKENHI-PROJECT-21H02938
  • [Journal Article] Mutant Lef1 controls Gata6 in sebaceous gland development and cancer2019

    • Author(s)
      Oules Benedicte、Rognoni Emanuel、Hoste Esther、Goss Georgina、Fiehler Ryan、Natsuga Ken、Quist Sven、Mentink Remco、Donati Giacomo、Watt Fiona M
    • Journal Title

      The EMBO Journal

      Volume: 印刷中 Issue: 9

    • DOI

      10.15252/embj.2018100526

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Efficient gene reframing therapy for recessive dystrophic epidermolysis bullosa using CRISPR/Cas92019

    • Author(s)
      Takashima Shota、Shinkuma Satoru、Fujita Yasuyuki、Nomura Toshifumi、Ujiie Hideyuki、Natsuga Ken、Iwata Hiroaki、Nakamura Hideki、Vorobyev Artem、Abe Riichiro、Shimizu Hiroshi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: in press Issue: 8 Pages: 1711-1721

    • DOI

      10.1016/j.jid.2019.02.015

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-19K08764, KAKENHI-PROJECT-17H01572
  • [Journal Article] Fc-binding proteins enhance autoantibody-induced BP180 depletion in pemphigoid2019

    • Author(s)
      Iwata H, Kamaguchi M, Ujiie H, Ujiie I, Natsuga K, Nishie W, ShimizuH:
    • Journal Title

      J Pathol

      Volume: 247 Issue: 3 Pages: 371-380

    • DOI

      10.1002/path.5196

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
  • [Journal Article] Bullous Pemphigoid IgG Induces Cell Dysfunction and Enhances the Motility of Epidermal Keratinocytes via Rac1/Proteasome Activation2019

    • Author(s)
      Tie Duerna、Da Xia、Natsuga Ken、Yamada Nanako、Yamamoto Osamu、Morita Eishin
    • Journal Title

      Frontiers in Immunology

      Volume: 10 Pages: 200-200

    • DOI

      10.3389/fimmu.2019.00200

    • NAID

      120007002182

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Intravenous IgG Reduces Pathogenic Autoantibodies, Serum IL-6 Levels, and Disease Severity in Experimental Bullous Pemphigoid Models2018

    • Author(s)
      Sasaoka Tetsumasa、Ujiie Hideyuki、Nishie Wataru、Iwata Hiroaki、Ishikawa Makoto、Higashino Hiroshi、Natsuga Ken、Shinkuma Satoru、Shimizu Hiroshi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 138 Issue: 6 Pages: 1260-1267

    • DOI

      10.1016/j.jid.2018.01.005

    • NAID

      120006636167

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Novel COL7A1 mutation in a family with bullous dermolysis of the newborn: Phenotypic variability associated with a COL7A1 mutation within the same family2018

    • Author(s)
      Takashima Shota、Shinkuma Satoru、Fujita Yasuyuki、Natsuga Ken、Nomura Toshifumi、Hida Tokimasa、Ishikawa Shuku、Nakamura Hideki、Abe Riichiro、Shimizu Hiroshi
    • Journal Title

      The Journal of Dermatology

      Volume: 印刷中 Issue: 9

    • DOI

      10.1111/1346-8138.14287

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K15540, KAKENHI-PROJECT-18K19531, KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-17K16317
  • [Journal Article] High Expression of Collagen XVII Compensates for Its Depletion Induced by Pemphigoid IgG in the Oral Mucosa.2018

    • Author(s)
      Kamaguchi M, Iwata H, Ujiie H, Natsuga K, Nishie W, Kitagawa Y, Shimizu H.
    • Journal Title

      J Invest Dermatol.

      Volume: - Issue: 8 Pages: 1707-1715

    • DOI

      10.1016/j.jid.2018.03.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
  • [Journal Article] Oral mucosa is a useful substrate for detecting autoantibodies of mucous membrane pemphigoid.2018

    • Author(s)
      Kamaguchi M, Iwata H, Ujiie H, Izumi K, Natsuga K, Nishie W, Asaka T, Kitagawa Y, Shimizu H.
    • Journal Title

      Br J Dermatol.

      Volume: 178 Issue: 2 Pages: e119-e121

    • DOI

      10.1111/bjd.15925

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
  • [Journal Article] Portable negative-pressure wound therapy for pyoderma gangrenosum: Report of two cases2018

    • Author(s)
      Yamaguchi Y, Yanagi T, Sato K, Yoshimoto N, Hirata Y, Ujiie I, Nishimura M, Natsuga K, Shiiya C, Tsukinaga I, Shimizu H
    • Journal Title

      J Dermatol

      Volume: 印刷中 Issue: 4 Pages: 483-486

    • DOI

      10.1111/1346-8138.14180

    • NAID

      120006600950

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Extensive Eruptive Syringoma After Liver Transplantation2018

    • Author(s)
      Maeda T、Natsuga K、Nishie W、Yamashita K、Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 98 Issue: 1 Pages: 119-120

    • DOI

      10.2340/00015555-2814

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Epidermal aspects of type VII collagen: Implications for dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita2018

    • Author(s)
      Watanabe Mika、Natsuga Ken、Shinkuma Satoru、Shimizu Hiroshi
    • Journal Title

      The Journal of Dermatology

      Volume: 45 Issue: 5 Pages: 515-521

    • DOI

      10.1111/1346-8138.14222

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H01572, KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-17K16317
  • [Journal Article] Life before and beyond blistering: The role of collagen XVII in epidermal physiology2018

    • Author(s)
      Natsuga K, Watanabe M, Nishie W, Shimizu H
    • Journal Title

      Exp Dermatol

      Volume: 印刷中 Issue: 10 Pages: 1135-1141

    • DOI

      10.1111/exd.13550

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Regulatory T-cell dysfunction induces autoantibodies to bullous pemphigoid antigens in mice and human subjects2018

    • Author(s)
      Muramatsu Ken、Ujiie Hideyuki、Kobayashi Ichiro、Nishie Wataru、Izumi Kentaro、Ito Takamasa、Yoshimoto Norihiro、Natsuga Ken、Iwata Hiroaki、Shimizu Hiroshi
    • Journal Title

      Journal of Allergy and Clinical Immunology

      Volume: 142 Issue: 6 Pages: 1818-1830.e6

    • DOI

      10.1016/j.jaci.2018.03.014

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Sweet's Syndrome Mimicking Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis2018

    • Author(s)
      Kosumi H, Watanabe M, Natsuga K, Miyauchi T, Shiiya C, Ujiie H, Shimizu H
    • Journal Title

      Am J Med

      Volume: 印刷中 Issue: 6 Pages: e241-e242

    • DOI

      10.1016/j.amjmed.2017.12.033

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] The direct binding of collagen XVII and collagen IV is disrupted by pemphigoid autoantibodies2018

    • Author(s)
      Kamaguchi Mayumi、Iwata Hiroaki、Nishie Wataru、Toyonaga Ellen、Ujiie Hideyuki、Natsuga Ken、Kitagawa Yoshimasa、Shimizu Hiroshi
    • Journal Title

      Laboratory Investigation

      Volume: 99 Issue: 1 Pages: 48-57

    • DOI

      10.1038/s41374-018-0113-9

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
  • [Journal Article] Acute vascular reaction due to lipo-prostaglandin E12018

    • Author(s)
      Fujimura Y, Watanabe M, Natsuga K, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 印刷中 Issue: 7

    • DOI

      10.1111/jdv.14807

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Loss of interaction between plectin and type XVII collagen results in epidermolysis bullosa simplex2017

    • Author(s)
      Natsuga K, Nishie W, Nishimura M, Shinkuma S, Watanabe M, Izumi K, Nakamura H, Hirako Y, Shimizu H
    • Journal Title

      Hum Mutat

      Volume: 38 Issue: 12 Pages: 1666-1670

    • DOI

      10.1002/humu.23344

    • NAID

      120006540047

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K10207, KAKENHI-PROJECT-17K16317
  • [Journal Article] Appearance of antidesmocollin 1 autoantibodies leading to a vegetative lesion in a patient with pemphigus vulgaris2017

    • Author(s)
      Yamaguchi Y.、Shinkuma S.、Ishii N.、Takashima S.、Natsuga K.、Ujiie H.、Iwata H.、Nomura T.、Fujita Y.、Hamasaka A.、Hamasaka K.、Hashimoto T.、Shimizu H.
    • Journal Title

      Br J Dermatol

      Volume: 178 Issue: 1 Pages: 294-295

    • DOI

      10.1111/bjd.15834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Crusted impetigo-like eruption on the face: A case report of IgG/IgA pemphigus2017

    • Author(s)
      Moriuchi R, Ito T, Kikuchi K, Nakashita N, Muramatsu R, Natsuga K, Shimizu H, Shimizu S
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 印刷中 Issue: 6

    • DOI

      10.1111/jdv.14060

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Psoriasiform mycosis fungoides masquerading as tumourous plaques2017

    • Author(s)
      Yamaguchi Y, Fujita Y, Hirata Y, Nishimura M, Shinkuma S, Natsuga K, Hida T, Kato N, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 印刷中 Issue: 3 Pages: 295-296

    • DOI

      10.1684/ejd.2017.2971

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-17K16317
  • [Journal Article] Generalized Pustular Psoriasis2017

    • Author(s)
      Kosumi Hideyuki、Ito Takamasa、Fujita Yasuyuki、Izumi Kentaro、Maya Yuka、Yanagi Teruki、Natsuga Ken、Ujiie Hideyuki、Shinkuma Satoru、Nomura Toshifumi、Sadanobu Naoya、Shimizu Hiroshi
    • Journal Title

      J Pediatr

      Volume: 188 Pages: 305-305.e1

    • DOI

      10.1016/j.jpeds.2017.05.058

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Autoantibodies of non-inflammatory bullous pemphigoid hardly deplete type XVII collagen of keratinocytes2017

    • Author(s)
      Imafuku K, Iwata H, Kamaguchi M, Izumi K, Natsuga K, Ujiie H, Nishie W, Shimizu H
    • Journal Title

      Exp Dermatol

      Volume: 印刷中 Issue: 12 Pages: 1171-1174

    • DOI

      10.1111/exd.13331

    • NAID

      120006540054

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-17K16317
  • [Journal Article] 出生前診断2017

    • Author(s)
      夏賀 健
    • Journal Title

      Visual Dermatology

      Volume: 16 Pages: 276-277

    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] C-Terminal Processing of Collagen XVII Induces Neoepitopes for Linear IgA Dermatosis Autoantibodies2017

    • Author(s)
      Toyonaga Ellen、Nishie Wataru、Izumi Kentaro、Natsuga Ken、Ujiie Hideyuki、Iwata Hiroaki、Yamagami Jun、Hirako Yoshiaki、Sawamura Daisuke、Fujimoto Wataru、Shimizu Hiroshi
    • Journal Title

      Journal of Investigative Dermatology

      Volume: 137 Issue: 12 Pages: 2552-2559

    • DOI

      10.1016/j.jid.2017.07.831

    • NAID

      120006540048

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K10207, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-26293254, KAKENHI-PROJECT-16H05365, KAKENHI-PROJECT-16K15539, KAKENHI-PROJECT-16K15541, KAKENHI-PROJECT-15KK0289
  • [Journal Article] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation in the COL7A1 gene2017

    • Author(s)
      Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 88 Issue: 1 Pages: 139-141

    • DOI

      10.1016/j.jdermsci.2017.03.022

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16K15540
  • [Journal Article] Early severe pachyonychia congenita subtype PC-K6a with a novel mutation in the KRT6A gene2017

    • Author(s)
      Cammarata-Scalisi F, Natsuga K, Toyonaga E, Nishie W, Shimizu H, Avendano A, Araque D, Da Silva G, Bellacchio E, Callea M
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 31 Issue: 2

    • DOI

      10.1111/jdv.13800

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation in the COL7A1 gene2017

    • Author(s)
      Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
    • Journal Title

      J Dermatol Sci

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Lichenoid drug eruption caused by clonazepam2017

    • Author(s)
      Muramatsu K, Ujiie H, Natsuga K, Nishie W, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 31 Issue: 2

    • DOI

      10.1111/jdv.13862

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Type XVII collagen coordinates proliferation in the interfollicular epidermis.2017

    • Author(s)
      Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuk Si, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt F and Shimizu H
    • Journal Title

      eLife

      Volume: 6:e26635 Pages: 1-24

    • DOI

      10.7554/elife.26635

    • NAID

      120006337772

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16H03949, KAKENHI-PROJECT-17H04022
  • [Journal Article] Cutis Verticis Gyrata Fluctuation with Atopic Dermatitis Disease Activity2017

    • Author(s)
      Kosumi H、Izumi K、Natsuga K、Yamaguchi Y、Itami A、Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: 97 Issue: 10 Pages: 1245-1246

    • DOI

      10.2340/00015555-2750

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Journal Article] Detection of mucous membrane pemphigoid autoantibodies by full-length BP180 enzyme-linked immunosorbent assay2017

    • Author(s)
      Izumi Kentaro、Nishie Wataru、Mai Yosuke、Ujiie Hideyuki、Iwata Hiroaki、Natsuga Ken、Shimizu Hiroshi
    • Journal Title

      J Dermatol Sci

      Volume: 88 Issue: 2 Pages: 247-248

    • DOI

      10.1016/j.jdermsci.2017.07.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-17K16318, KAKENHI-PROJECT-16H05365, KAKENHI-PROJECT-16K15539, KAKENHI-PROJECT-15KK0289
  • [Journal Article] Mucocutaneous pyoderma gangraenosum due to trisomy 8 neutrophilic infiltrates in a patient with myelodysplastic syndrome2016

    • Author(s)
      Haga N, Iwata H, Yamaguchi Y, Shirato T, Nishimura K, Yamane N, Shinkuma S, Natsuga K, Kondo T, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 174 Issue: 1 Pages: 239-241

    • DOI

      10.1111/bjd.14102

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Autoantibody profile differentiates between inflammatory and noninflammatory bullous pemphigoid.2016

    • Author(s)
      Izumi K, Nishie W, Mai Y, Wada M, Natsuga K, Ujiie H, Iwata H, Yamagami J, Shimizu H
    • Journal Title

      J Invest Dermatol

      Volume: 136 Issue: 11 Pages: 2201-2210

    • DOI

      10.1016/j.jid.2016.06.622

    • NAID

      120006360054

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-16H05365, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-16K15539
  • [Journal Article] Extensive Erythema and Hyperkeratosis on the Extremities and Lumbar Area as an Unusual Mani-festation of Nagashima-type Palmoplantar Keratosis2016

    • Author(s)
      Miyauchi T, Nomura T, Suzuki S, Ohguchi Y, Yamaguchi Y, Shinkuma S, Natsuga K, Fujita Y, Shimizu H.
    • Journal Title

      Acta Dermato-Venereologica

      Volume: in press Pages: 856-858

    • DOI

      10.2340/00015555-2391

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K19668
  • [Journal Article] Verrucous hyperplasia associated with neuropathy from schistorrhachis2016

    • Author(s)
      Imafuku K, Hata H, Inamura Y, Kitamura S, Natsuga K, Iwata H, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 30 Issue: 5 Pages: 876-878

    • DOI

      10.1111/jdv.13042

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Macropinocytosis of type XVII collagen induced by bullous pemphigoid IgG is regulated via protein kinase C2016

    • Author(s)
      Iwata H, Ujiie H, Nishimura M, Izumi K, Natsuga K, Shinkuma S, Nishie W, Shimizu H
    • Journal Title

      Lab Invest

      Volume: 96 Issue: 12 Pages: 1301-1310

    • DOI

      10.1038/labinvest.2016.108

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Metal implant-induced skin ulcer mimicking scrofuloderma2016

    • Author(s)
      Kitamura S, Natsuga K*, Imafuku K, Homma E, Yamane N, Aoyagi S, Matsumura T, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 30 Issue: 3 Pages: 449-450

    • DOI

      10.1111/jdv.12825

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Nodular morphoea: a first case associated with linear morphoea2016

    • Author(s)
      Nakazato S, Nomura T, Yamane N, Shinkuma S, Natsuga K, Fujita Y, Arita K, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 26 Issue: 1 Pages: 95-96

    • DOI

      10.1684/ejd.2015.2656

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-25461681, KAKENHI-PROJECT-15K19668
  • [Journal Article] Stem cell markers of skin appendages in human skin tumours2016

    • Author(s)
      Natsuga K
    • Journal Title

      Br J Dermatol

      Volume: 175 Issue: 3 Pages: 459-459

    • DOI

      10.1111/bjd.14655

    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Silicone medical adhesive removers for hyperkeratosis in epidermolysis bullosa2016

    • Author(s)
      Fujita Y, Shinkuma S, Matsumura W, Natsuga K, Hata H, Nomura T, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 26 Issue: 5 Pages: 501-502

    • DOI

      10.1684/ejd.2016.2817

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Epitope-dependent pathogenicity of Abs targeting a major bullous pemphigoid autoAg collagen XVII/BP1802016

    • Author(s)
      Wada M, Nishie W*, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H:
    • Journal Title

      J Invest Dermatol

      Volume: 136 Pages: 938-946

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Journal Article] Pyoderma gangrenosum associated with acute respiratory distress syndrom2016

    • Author(s)
      Watanabe M, Natsuga K, Ota M, Ito K
    • Journal Title

      Am J Med

      Volume: 129 Issue: 2 Pages: e17-e18

    • DOI

      10.1016/j.amjmed.2015.08.035

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Increased bacterial load and expression of antimicrobial peptides in skin of barrier-deficient mice with reduced cancer susceptibility2016

    • Author(s)
      Natsuga K, Cipolat S, Watt FM
    • Journal Title

      J Invest Dermatol

      Volume: 136 Issue: 1 Pages: 99-106

    • DOI

      10.1038/jid.2015.383

    • NAID

      120005822527

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Epidermolysis bullosa acquisita develops in dominant dystrophic epidermolysis bullosa2016

    • Author(s)
      Hayashi R, Natsuga K, Watanabe M, Iwata H, Shinkuma S, Ito A, Masui Y, Ito M, Shimomura Y
    • Journal Title

      J Invest Dermatol

      Volume: 136 Issue: 1 Pages: 320-323

    • DOI

      10.1038/jid.2015.370

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Concomitant neoplasms in skin and stomach unveil the role of type IV collagen and E-cadherin in MUC5AC expression in vivo2016

    • Author(s)
      Hata H, Natsuga K, Kitamura S, Imafuku K, Yamaguchi Y, Ebihara Y, Shichinohe T, Hirano S, Shimizu H
    • Journal Title

      Br J Dermatol

      Volume: 174 Issue: 2 Pages: 395-397

    • DOI

      10.1111/bjd.14084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Anti-laminin-gamma 1 pemphigoid with generalized pustular psoriasis and psoriasis vulgaris2016

    • Author(s)
      Fujimura Y, Natsuga K*, Hamade Y, Nomura Y, Kaku Y, Muramatsu R, Shimizu H
    • Journal Title

      Acta Dermato-Venereol

      Volume: 96 Issue: 1 Pages: 120-121

    • DOI

      10.2340/00015555-2168

    • NAID

      120005722550

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] mTOR expression correlates with invasiveness and progression of extramammary Paget's disease2016

    • Author(s)
      Hata H, Kitamura S, Inamura Y, Imafuku K, Homma E, Muramatsu K, Natsuga K, Abe R, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 30 Issue: 7 Pages: 1238-1239

    • DOI

      10.1111/jdv.13168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Extracellular cleavage of collagen XVII is essential for correct cutaneous basement membrane formation.2016

    • Author(s)
      Nishimura M, Nishie W, Shirafuji Y, Shinkuma S, Natsuga K, Nakamura H, Sawamura D, Iwatsuki K, Shimizu H
    • Journal Title

      Hum Mol Genet

      Volume: 15;25(2) Issue: 2 Pages: 328-39

    • DOI

      10.1093/hmg/ddv478

    • NAID

      120005868259

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-15K15409, KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-26293254, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-15KK0289
  • [Journal Article] Galectin-6 is a novel skin anti-microbial peptide that is modulated by the skin barrier and microbiome2016

    • Author(s)
      Natsuga K, Watt FM
    • Journal Title

      J Dermatol Sci

      Volume: 84 Issue: 1 Pages: 97-99

    • DOI

      10.1016/j.jdermsci.2016.06.008

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Epitope-Dependent Pathogenicity of Antibodies Targeting a Major Bullous Pemphigoid Autoantigen Collagen XVII/BP180.2016

    • Author(s)
      Wada M, Nishie W, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H
    • Journal Title

      J Invest Dermatol

      Volume: in press Issue: 5 Pages: 938-946

    • DOI

      10.1016/j.jid.2015.11.030

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-15K19668
  • [Journal Article] Mucosal hyperpigmentation from prophylactic minocycline for EGFR inhibitor2016

    • Author(s)
      Imafuku K, Natsuga K*, Aoyagi S, Shimizu H
    • Journal Title

      J Eur Acad Dermatol Venereol

      Volume: 30 Issue: 4 Pages: 690-692

    • DOI

      10.1111/jdv.12978

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Two cases of erosive oral lichen planus with non-pathogenic autoantibodies to desmoglein 32016

    • Author(s)
      Muramatsu K, Nishie W, Natsuga K, Fujita Y, Iwata H, Yamada T, Yamashita E, Asaka T, Shimizu H
    • Journal Title

      J Dermatol

      Volume: 43 Issue: 11 Pages: 1350-1353

    • DOI

      10.1111/1346-8138.13493

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Anti-BP180-type mucous membrane pemphigoid: Report of two cases2016

    • Author(s)
      Wada M, Sato J, Shindoh M, Ujiie H, Natsuga K, Nishie W, Shimizu H, Kitagawa Y
    • Journal Title

      Odontology

      Volume: 104 Issue: 1 Pages: 114-118

    • DOI

      10.1007/s10266-014-0181-2

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Context-Dependent Regulation of Collagen XVII Ectodomain Shedding in Skin.2015

    • Author(s)
      Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, Nakamura H, Shimizu H.
    • Journal Title

      Am J Pathol

      Volume: in press Issue: 5 Pages: 1361-71

    • DOI

      10.1016/j.ajpath.2015.01.012

    • NAID

      120005752843

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-26670516, KAKENHI-PROJECT-15K19668
  • [Journal Article] Bowen’s disease on the palm presents refractory skin erosion without erythematous plaque2015

    • Author(s)
      Kitamura S, Iwata H, Imafuku K, Hata H, Natsuga K, Aoyagi S, Shimizu H
    • Journal Title

      J Dermatol

      Volume: 42 Issue: 2 Pages: 225-6

    • DOI

      10.1111/1346-8138.12745

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Plectin-related skin diseases2015

    • Author(s)
      Natsuga K
    • Journal Title

      J Dermatol Sci

      Volume: 77 Issue: 3 Pages: 139-45

    • DOI

      10.1016/j.jdermsci.2014.11.005

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Journal Article] Generalized acute subcutaneous edema as a rare cutaneous manifestation of severe dermatomyositis.2015

    • Author(s)
      Watanabe M, Natsuga K, Arita K, Abe R, Shimizu H.
    • Journal Title

      Journal of European Academy of Dermatology and Venereology

      Volume: in press Issue: 11

    • DOI

      10.1111/jdv.13460

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461681, KAKENHI-PROJECT-15K19668
  • [Journal Article] Plasma cell cheilitis extending beyond vermillion border2015

    • Author(s)
      Fujimura Y, Natsuga K*, Abe R, Morita Y, Nomura T, Shimizu H
    • Journal Title

      J Dermatol

      Volume: 42 Issue: 9 Pages: 935-6

    • DOI

      10.1111/1346-8138.12985

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-15H04780
  • [Journal Article] Context-Dependent Regulation of Collagen XVII Ectodomain Sheddingin Skin.2015

    • Author(s)
      Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, NakamuraH, Shimizu H
    • Journal Title

      Am J Pathol

      Volume: 185(5) Pages: 1361-71

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Journal Article] In vivo analysis of IgE autoantibodies in bullous pemphigoid: A study of 100 cases.2015

    • Author(s)
      Moriuchi R, Nishie W, Ujiie H, Natsuga K, Shimizu H.
    • Journal Title

      J Dermatol Sci

      Volume: 78 Issue: 1 Pages: 21-25

    • DOI

      10.1016/j.jdermsci.2015.01.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-26670516, KAKENHI-PROJECT-15K19668
  • [Journal Article] Skipped exon in COL7A1 determines the clinical phenotypes of dystrophic epidermolysis bullosa.2015

    • Author(s)
      Toyonaga E, Nishie W, Komine M, Murata S, Shinkuma S, Natsuga K, Nakamura H, Ohtsuki M, Shimizu H.
    • Journal Title

      British Journal of Dermatology

      Volume: 172 Issue: 4 Pages: 1141-1144

    • DOI

      10.1111/bjd.13386

    • Peer Reviewed / Acknowledgement Compliant
    • Data Source
      KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-25461661
  • [Journal Article] Non-solar-induced elastotic bands on the forearm2015

    • Author(s)
      Haga N, Abe R, Morita Y, Fujimura Y, Natsuga K, Nomura T, Kumakiri M, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 25 Issue: 5 Pages: 508-9

    • DOI

      10.1684/ejd.2015.2629

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-15H04780
  • [Journal Article] Bullous Pemphigoid Autoantibodies Directly Induce Blister Formation without Complement Activation.2014

    • Author(s)
      Ujiie H, Sasaoka T, Izumi K, Nishie W, Shinkuma S, Natsuga K, Nakamura H, Shibaki A, Shimizu H
    • Journal Title

      The Journal of Immunology

      Volume: 193 Issue: 9 Pages: 4415-4428

    • DOI

      10.4049/jimmunol.1400095

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Journal Article] Dermoscopic Features of Plasma Cell Cheilitis and Actinic Cheilitis2014

    • Author(s)
      Ito T, Natsuga K, Tanimura S, Aoyagi S, Shimizu H
    • Journal Title

      Acta Derm Venereol

      Volume: (in press) Issue: 5 Pages: 593-594

    • DOI

      10.2340/00015555-1795

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Ultrasound B-mode and Elastographic Findings of Angiomatoid Fibrous Histiocytoma2014

    • Author(s)
      Hata H, Natsuga K, Homma E, Aoyagi S, Shimizu H
    • Journal Title

      Clin Exp Dermatol

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Paper-Based ELISA for the Detection of Autoimmune Antibodies in Body Fluid-The Case of Bullous Pemphigoid2014

    • Author(s)
      Hsu CK, Huang HY, Chen WR, Nishie W, Ujiie H, Natsuga K, Fan ST, Wang HK, Lee JY, Tsai WL, Shimizu H, Cheng CM
    • Journal Title

      Anal Chem

      Volume: (in press) Issue: 9 Pages: 4605-4610

    • DOI

      10.1021/ac500835k

    • Year and Date
      2014-04-27
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Epidermal Wnt/beta-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors2014

    • Author(s)
      Donati G, Proserpio V, Lichtenberger BM, Natsuga K, Sinclair R, Fujiwara H, Watt FM
    • Journal Title

      Proc Natl Acad Sci U S A

      Volume: 111 Issue: 15

    • DOI

      10.1073/pnas.1312880111

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494, KAKENHI-PUBLICLY-25122720
  • [Journal Article] Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility2014

    • Author(s)
      Cipolat S, Hoste E, Natsuga K, Quist S, Watt FM
    • Journal Title

      eLife

      Volume: 印刷中

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Epidermal Barriers2014

    • Author(s)
      Natsuga K
    • Journal Title

      Cold Spring Harb Perspect Med

      Volume: 4 Issue: 4 Pages: a018218-a018218

    • DOI

      10.1101/cshperspect.a018218

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis2013

    • Author(s)
      Cottle DL, Kretzschmar K, Schweiger PJ, Quist SR, Gollnick HP, Natsuga K, Aoyagi S, Watt FM
    • Journal Title

      Cell Rep

      Volume: 3 Issue: 2 Pages: 427-441

    • DOI

      10.1016/j.celrep.2013.01.013

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Jacyk、Ken Natsuga、Hideyuki Ujiie、Hideki Nakamura、Masashi Akiyama、Hiroshi Shimizu2013

    • Author(s)
      Satoru Shinkuma、Wataru Nishie、 Witold K
    • Journal Title

      A Novel Keratin 5 Mutation in an African Family with Epidermolysis Bullosa Simplex Indicates the Importance of the Amino Acid Located at the Boundary Site Between the H1 and Coil 1A Domains

      Volume: 印刷中 Issue: 5 Pages: 585-587

    • DOI

      10.2340/00015555-1538

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23890006, KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24659516, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
  • [Journal Article] Coexistence case of bullous pemphigoid and pemphigus foliaceus2013

    • Author(s)
      Tsujiwaki M, Abe R, Nomura Y, Nishimura M, Hoshina D, Shinkuma S, Natsuga K, Ujiie H, Arita K, Shimizu H
    • Journal Title

      Eur J Dermatol

      Volume: 23 Issue: 4 Pages: 552-553

    • DOI

      10.1684/ejd.2013.2084

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and-independent manner2012

    • Author(s)
      Natsuga K, Nishie W, et al.
    • Journal Title

      J Immunol

      Volume: 188 Pages: 5792-9

    • NAID

      10031131103

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24390274
  • [Journal Article] Ultrasound B-mode and Elastographic Findings of Angiomatoid Fibrous Histiocytoma.

    • Author(s)
      Hata H, Natsuga K, Homma E, Aoyagi S, Shimizu H
    • Journal Title

      Clin Exp Dermatol

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Journal Article] Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility

    • Author(s)
      Cipolat S, Hoste E, Natsuga K, Quist S, Watt FM
    • Journal Title

      eLife

      Volume: (in press)

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] Conformational epitope mapping of autoantibodies against BP180 in dipeptidyl peptidase-4 inhibitors-associated bullous pemphigoid2023

    • Author(s)
      Shoko Mai, Kentaro Izumi, Yosuke Mai, Ken Natsuga, Wataru Nishie, and Hideyuki Ujiie
    • Organizer
      International Societies for Investigative Dermatology 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02938
  • [Presentation] Type XVII collagen-specific CD4+ T cell clones induce bullous pemphigoid in mice by producing IL-52023

    • Author(s)
      Norihiro Yoshimoto, Ken Muramatsu, Takamasa Ito, Zheng Miao, Kentaro Izumi, Ken Natsuga, Hiroaki Iwata, Yoshinori Hasegawa, Hiroshi Shimizu, Hideyuki Ujiie
    • Organizer
      International Societies for Investigative Dermatology 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02938
  • [Presentation] Aged mice produce IgM autoantibodies against the basement membrane zone2023

    • Author(s)
      Chihiro Shiiya, Ken Muramatsu, Norihiro Yoshimoto, Sho Katayama, Takuya Kawamura, Shoko Mai, Yosuke Mai, Hiroyuki Kitahata, Ken Natsuga, Hiroaki Iwata, Kentaro Izumi, Hideyuki Ujiie
    • Organizer
      International Societies for Investigative Dermatology 2023
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02938
  • [Presentation] Type XVII collagen-specific CD4+ T cell clones induce the phenotype of bullous pemphigoid in mice by producing Th2 cytokines2022

    • Author(s)
      Norihiro Yoshimoto, Ken Muramatsu, Takamasa Ito, Zheng Miao, Ken Natsuga, Wataru Nishie, Hiroaki Iwata, Yoshinori Hasegawa, Hiroshi Shimizu, Hideyuki Ujiie
    • Organizer
      The 47th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-21H02938
  • [Presentation] 表皮の恒常性維持と外的刺激に対する応答2019

    • Author(s)
      夏賀 健
    • Organizer
      第1回炎症性皮膚疾患集中セミナー
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Presentation] Differences in collagen XVII expression between skin and oral mucosa affect the pathogenicity of pemphigoid IgG2018

    • Author(s)
      .Kamaguchi M, Iwata H, Ujiie H, Natsuga K, Nishie W, Asaka T, Shimizu H, Kitagawa Y.
    • Organizer
      14th Biennial Congress of the European Association of Oral Medicine Gotenbrug, Sweden.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Clavus serves as a model of epidermal stem cell responses to mechanical forces2018

    • Author(s)
      Natsuga K, Watanabe M, Hata H, Kobayashi Y, Nagayama M, Shimizu H
    • Organizer
      International Investigative Dermatology 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Presentation] 表皮化水疱症 発症機序/新規治療法の最新の進歩2018

    • Author(s)
      夏賀 健
    • Organizer
      第117回日本皮膚科学会総会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Presentation] Organization of the epidermal basement membrane zone determined through super-resolution microscopy2018

    • Author(s)
      Natsuga K, Watanabe M, Shimizu H
    • Organizer
      7th SSSR and SCUR meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Presentation] Abnormalities in laminin-332 have post-translational effects on laminin γ22017

    • Author(s)
      Natsuga K, Nishie W, Watanabe M, Nakamura H, Shinkuma S, Shimizu H
    • Organizer
      EB2017 - 5th World Conference of EB Research & 4th Conference of EB-CLINET
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K16317
  • [Presentation] Abnormalities in laminin-332 have post-translational effects on laminin γ22017

    • Author(s)
      Natsuga K, Nishie W, Watanabe M, Nakamura H, Shinkuma S, Shimizu H
    • Organizer
      EB2017 - 5th World Conference of EB Research
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation.2017

    • Author(s)
      Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
    • Organizer
      The 76th Annual Meeting of the Society for Investigative Dermatology.
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Characterization of non-hemidesmosomal collagen XVII in basal keratinocytes2016

    • Author(s)
      Natsuga K, Watanabe M, Nishie W, Shimizu H
    • Organizer
      41th Annual Meeting of the Japanese Society for Investigative Dermatology (JSID)
    • Place of Presentation
      仙台国際センター(宮城県仙台市)
    • Year and Date
      2016-12-09
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Presentation] 皮膚基底膜構築における17型コラーゲン細胞外領域切断の生理機能の解析2016

    • Author(s)
      西村真智子, 西江渉, 新熊悟, 夏賀健, 中村秀樹, 白藤宜紀, 岩月啓氏, 澤村大輔, 清水宏
    • Organizer
      第407回日本皮膚科学会北海道地方会
    • Place of Presentation
      札幌医大、札幌市
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Defective binding of plectin and collagen XVII leads to epidermolysis bullosa simplex.2016

    • Author(s)
      Natsuga K, Nihsie W, Nishimura M, Shinkuma S, Watanabe M, Izumi K, Nakamura H, Hirako Y, Shimizu H
    • Organizer
      The 46th Annual European Society for Dermatological Research meeting.
    • Place of Presentation
      Technical University of Munich, Munich, Germany
    • Year and Date
      2016-09-07
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K10120
  • [Presentation] Organization of the Basement Membrane Zone: Implications for Epidermolysis Bullosa2016

    • Author(s)
      Natsuga K
    • Organizer
      第115回日本皮膚科学会総会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Presentation] 表皮細胞の分化・増殖における基底膜の役割2016

    • Author(s)
      夏賀 健
    • Organizer
      第115回日本皮膚科学会総会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Presentation] アトピー性皮膚炎/魚鱗癬における細菌叢と抗菌ペプチド2016

    • Author(s)
      夏賀 健
    • Organizer
      第115回日本皮膚科学会総会
    • Place of Presentation
      京都国際会館(京都府京都市)
    • Invited
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Presentation] 全長XVII型コラーゲンを抗原としたELISAによる粘膜類天疱瘡患者自己抗体の検出2015

    • Author(s)
      泉 健太郎、西江 渉、夏賀 健、岩田浩明、氏家英之、清水 宏
    • Organizer
      第37回水疱症研究会
    • Place of Presentation
      コラッセ福島、福島市
    • Year and Date
      2015-09-26
    • Data Source
      KAKENHI-PROJECT-24390274
  • [Presentation] A single laminin subunit deficiency alters other laminin expression depending on the mutated genes.2015

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Nakamura H, Watanabe M, Kambe M, Hatamochi A, Kimura U, Suga Y, Shimizu H
    • Organizer
      The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Okayama convention center, Okayama, Okayama-City
    • Year and Date
      2015-12-11
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] A single laminin subunit deficiency alters other laminin expression depending on the mutated genes2015

    • Author(s)
      Natsuga K, Nishie W, Shinkuma S, Nakamura H, Watanabe M, Kambe N, Hatamochi A, Kimura U, Suga Y, Shimizu H
    • Organizer
      40th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Okayama, Japan
    • Year and Date
      2015-12-11
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K19668
  • [Presentation] 全長XVII型コラーゲンを抗原としたELISAによる粘膜類天疱瘡患者自己抗体の検出2015

    • Author(s)
      泉 健太郎、西江 渉、夏賀 健、岩田浩明、氏家英之、清水 宏
    • Organizer
      第37回水疱症研究会
    • Place of Presentation
      コラッセ福島、福島県、福島市
    • Year and Date
      2015-09-26
    • Data Source
      KAKENHI-PROJECT-15K15409
  • [Presentation] Pathogenetic mechanisms in autoimmune skin fragility2013

    • Author(s)
      Natsuga K
    • Organizer
      The 40th Annual Meeting of Society for Cutaneous Ultrastructure Research
    • Place of Presentation
      Castellani Parkhotel Salzburg (Austria)
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] Skin barrier defect allows more abundant microbiota in skin and induces skin inflammation and the expression of antimicrobial peptides independently of microbiota : Skin barrier defect allows more abundant microbiota in skin and induces skin inflammation and the expression of antimicrobial peptides independently of microbiota.2013

    • Author(s)
      Natsuga K, Cipolat S, Watt FM
    • Organizer
      The International Investigative Dermatology 2013
    • Place of Presentation
      Edinburgh, Scotland
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] Pathogenetic mechanisms in autoimmune skin fragility.2013

    • Author(s)
      Natsuga K
    • Organizer
      The 40th Annual Meeting of Society for Cutaneous Ultrastructure Research
    • Place of Presentation
      Salzburg, Austria
    • Invited
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] Essential role of collagen XVII in basement membrane formation and keratinocyte migration.2013

    • Author(s)
      Nishimura M, Nihsie W, Shinkuma S, Natsuga K, Nakamura H, Sawamura D, Iwatsuki K, Shimizu H
    • Organizer
      The International Investigative Dermatology
    • Place of Presentation
      Edinburgh International Conference Centre (Scotland)
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] Skin barrier defect allows more abundant microbiota in skin and induces skin inflammation and the expression of antimicrobial peptides independently of microbiota2013

    • Author(s)
      Natsuga K, Cipolat S, Watt FM
    • Organizer
      International Investigative Dermatology 2013
    • Place of Presentation
      Edinburgh International Conference Centre (UK)
    • Data Source
      KAKENHI-PROJECT-25670494
  • [Presentation] One amino acid deletion in type XII collagen-binding domain of plectin with a truncation mutation underlies epidermolysis bullosa simplex.

    • Author(s)
      Natsuga K, Nishie W, Nishimura M, Nakamura H, Shimizu H.
    • Organizer
      The 39th Annual Meeting of the Japanese Society of Invesitigative Dermatology
    • Place of Presentation
      ホテル阪急エキスポパーク(吹田市)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-26670516
  • [Presentation] Context-dependent tight regulation of collagen XVII ectodomain shedding in skin.

    • Author(s)
      Nishie W, Natsuga K, Izumi K, Ujiie H, Hata H, Nakamura H, Shimizu H
    • Organizer
      The 39th Annual Meeting of the Japanese Society of Invesitigative Dermatology
    • Place of Presentation
      ホテル阪急エキスポパーク(吹田市)
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-24390274
  • [Presentation] One amino acid deletion in collagen XVII-binding domain of plectin with a truncation mutation underlies epidermolysis bullosa simplex.

    • Author(s)
      Natsuga K, Nishimura M, Nakamura H, Nihsie W, Shimizu H
    • Organizer
      The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Hotel Hankyu Expo Park, Osaka, Suita-City
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25461661
  • [Presentation] Context-dependent tight regulation of collagen XVII ectodomain shedding in skin.

    • Author(s)
      Nihsie W, Natsuga K, Izumi K, Hata H, Nakamura H, Shimizu H
    • Organizer
      The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
    • Place of Presentation
      Hotel Hankyu Expo Park, Osaka, Suita-City
    • Year and Date
      2014-12-12 – 2014-12-14
    • Data Source
      KAKENHI-PROJECT-25461661
  • 1.  Nishie Wataru (20443955)
    # of Collaborated Projects: 9 results
    # of Collaborated Products: 24 results
  • 2.  UJIIE HIDEYUKI (60374435)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 12 results
  • 3.  SHIMIZU Hiroshi (00146672)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 27 results
  • 4.  岩田 浩明 (20397334)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 7 results
  • 5.  泉 健太郎 (50793668)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 5 results
  • 6.  Nakamura Hideki (60435956)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 16 results
  • 7.  Watanabe Mika
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 8.  Fujimura Yu
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 4 results
  • 9.  SHINKUMA SATORU (00613788)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 10.  Fujita Yasuyuki (80374437)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  乃村 俊史 (50399911)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 12.  柳 輝希 (50755973)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  眞井 洋輔 (00972308)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  長山 雅晴 (20314289)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  高島 翔太 (60962800)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  MATSUMURA WAKANA
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  NAKAYAMA CHIHIRO
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  TOYONAGA ellen
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  ARITA Ken
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 20.  平子 善章
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 21.  築山 忠維
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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