Natsuga Ken 夏賀健

… Alternative Names

NATSUGA Ken 夏賀健

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Researcher Number	70645457
Other IDs
External Links
Affiliation (Current)	2025: 北海道大学, 医学研究院, 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 北海道大学, 医学研究院, 准教授 2020 – 2021: 北海道大学, 大学病院, 講師 2016 – 2018: 北海道大学, 大学病院, 講師 2015: 北海道大学, 北海道大学病院, 助教 2013 – 2015: 北海道大学, 大学病院, 助教
Review Section/Research Field	Principal Investigator Dermatology / Basic Section 53050:Dermatology-related Except Principal Investigator Dermatology / Basic Section 53050:Dermatology-related
Keywords	Principal Investigator 表皮水疱症 / 再生医学 / 幹細胞 / 毛包 / 表皮 / 創傷治癒 / 細胞外マトリクス / 自己抗原 / 自己抗体 Except Principal Investigator 皮膚病態学 … More / 皮膚病態斈 / 免疫寛容 / 表皮水疱症 / 自己免疫性水疱症 / 17型コラーゲン / 水疱性類天疱瘡 / 皮膚病理学 / Age-associated B cell / 制御性T細胞 / 水疱症 / 免疫チェックポイント阻害薬 / DPP-4阻害薬 / 7型コラーゲン / BP180 / 類天疱瘡 / 加齢 / 自己免疫疾患 / 瘢痕型脱毛症 / 自己抗体 / コラーゲン / 細菌叢 / 皮膚基底膜 / 皮膚細菌叢 / COL17 / プラスミン / 自己免疫 / 酵素 / 細胞・組織 / タンパク質 / 生体分子 Less

Identifying and overcoming factors contributing to delayed wound healing in epidermolysis bullosa.Principal Investigator
- Principal Investigator
  
  夏賀健
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Hokkaido University
Elucidation of the mechanism of the breakdown of cutaneous immune tolerance focusing on aging
- Principal Investigator
  
  Ujiie Hideyuki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Hokkaido University
エピトープスプレディング現象に着目した水疱性類天疱瘡の病態解明
- Principal Investigator
  
  西江渉
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53050:Dermatology-related
- Research Institution
  Hokkaido University
Dynamics of epithelial stem cells upon woundingPrincipal Investigator
- Principal Investigator
  
  Natsuga Ken
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Novel bullous pemphigoid models induced by breaking tolerance to autoantigens.
- Principal Investigator
  
  Nishie Wataru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Establishment of cicatricial alopecia animal models
- Principal Investigator
  
  Nakamura Hideki
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Pathogenesis of bullous pemphigoid: a study using class-switched monoclonal antibodies.
- Principal Investigator
  
  Nishie Wataru
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Treatment of epidermolysis bullosa with revertant keratinocyte-derived iPS cells
- Principal Investigator
  
  Fujita Yasuyuki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Prevention of autoantigen depletion for bullous pemphigoid treatmentPrincipal Investigator
- Principal Investigator
  
  Natsuga Ken
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Induction of tolerance to bullous pemphigoid autoantigen by oral administration of antigenic peptides.
- Principal Investigator
  
  Nishie Wataru
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Generation of mosaic model of epidermolysis bullosa by inactivation of X chromosome.
- Principal Investigator
  
  NISHIE Wataru
- Project Period (FY)
  2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Elucidating roles of plasmin in blister formation of bullous pemphigoid
- Principal Investigator
  
  Nakamura Hideki
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Modulation of skin microbiota through basememt membrane
- Principal Investigator
  
  SHIMIZU Hiroshi
- Project Period (FY)
  2013
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University
Production of a novel blistering disease model by regulating expression of collagen XVII
- Principal Investigator
  
  Nishie Wataru
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Dermatology
- Research Institution
  Hokkaido University

All 2023 2022 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book

[Book] Current Genetics in Dermatology2013
- Author(s)
  Natsuga K
- Total Pages
  16
- Publisher
  INTECH
- Data Source
  KAKENHI-PROJECT-25670494
[Book] Epidermolysis bullosa simplex Current Genetics in Dermatology2013
- Author(s)
  Natsuga K
- Publisher
  Intech
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Native Autoantigen Complex Detects Pemphigoid Autoantibodies2023
- Author(s)
  Mai Shoko、Izumi Kentaro、Mai Yosuke、Natsuga Ken、Ishii Norito、Sawamura Daisuke、Schauer Franziska、Kiritsi Dimitra、Nishie Wataru、Ujiie Hideyuki
- Journal Title
  
  JID Innovations
  
  Volume: 3 Issue: 3 Pages: 100193-100193
- DOI
  10.1016/j.xjidi.2023.100193
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K17334, KAKENHI-PROJECT-22K08419, KAKENHI-PROJECT-21K08316, KAKENHI-PROJECT-21H02938
[Journal Article] Mutant Lef1 controls Gata6 in sebaceous gland development and cancer2019
- Author(s)
  Oules Benedicte、Rognoni Emanuel、Hoste Esther、Goss Georgina、Fiehler Ryan、Natsuga Ken、Quist Sven、Mentink Remco、Donati Giacomo、Watt Fiona M
- Journal Title
  
  The EMBO Journal
  
  Volume: 印刷中 Issue: 9
- DOI
  10.15252/embj.2018100526
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Efficient gene reframing therapy for recessive dystrophic epidermolysis bullosa using CRISPR/Cas92019
- Author(s)
  Takashima Shota、Shinkuma Satoru、Fujita Yasuyuki、Nomura Toshifumi、Ujiie Hideyuki、Natsuga Ken、Iwata Hiroaki、Nakamura Hideki、Vorobyev Artem、Abe Riichiro、Shimizu Hiroshi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: in press Issue: 8 Pages: 1711-1721
- DOI
  10.1016/j.jid.2019.02.015
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-19K08764, KAKENHI-PROJECT-17H01572
[Journal Article] Fc-binding proteins enhance autoantibody-induced BP180 depletion in pemphigoid2019
- Author(s)
  Iwata H, Kamaguchi M, Ujiie H, Ujiie I, Natsuga K, Nishie W, ShimizuH:
- Journal Title
  
  J Pathol
  
  Volume: 247 Issue: 3 Pages: 371-380
- DOI
  10.1002/path.5196
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
[Journal Article] Bullous Pemphigoid IgG Induces Cell Dysfunction and Enhances the Motility of Epidermal Keratinocytes via Rac1/Proteasome Activation2019
- Author(s)
  Tie Duerna、Da Xia、Natsuga Ken、Yamada Nanako、Yamamoto Osamu、Morita Eishin
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 10 Pages: 200-200
- DOI
  10.3389/fimmu.2019.00200
- NAID
  120007002182
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Intravenous IgG Reduces Pathogenic Autoantibodies, Serum IL-6 Levels, and Disease Severity in Experimental Bullous Pemphigoid Models2018
- Author(s)
  Sasaoka Tetsumasa、Ujiie Hideyuki、Nishie Wataru、Iwata Hiroaki、Ishikawa Makoto、Higashino Hiroshi、Natsuga Ken、Shinkuma Satoru、Shimizu Hiroshi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 138 Issue: 6 Pages: 1260-1267
- DOI
  10.1016/j.jid.2018.01.005
- NAID
  120006636167
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Novel COL7A1 mutation in a family with bullous dermolysis of the newborn: Phenotypic variability associated with a COL7A1 mutation within the same family2018
- Author(s)
  Takashima Shota、Shinkuma Satoru、Fujita Yasuyuki、Natsuga Ken、Nomura Toshifumi、Hida Tokimasa、Ishikawa Shuku、Nakamura Hideki、Abe Riichiro、Shimizu Hiroshi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 印刷中 Issue: 9
- DOI
  10.1111/1346-8138.14287
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K15540, KAKENHI-PROJECT-18K19531, KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-17K16317
[Journal Article] High Expression of Collagen XVII Compensates for Its Depletion Induced by Pemphigoid IgG in the Oral Mucosa.2018
- Author(s)
  Kamaguchi M, Iwata H, Ujiie H, Natsuga K, Nishie W, Kitagawa Y, Shimizu H.
- Journal Title
  
  J Invest Dermatol.
  
  Volume: - Issue: 8 Pages: 1707-1715
- DOI
  10.1016/j.jid.2018.03.002
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
[Journal Article] Oral mucosa is a useful substrate for detecting autoantibodies of mucous membrane pemphigoid.2018
- Author(s)
  Kamaguchi M, Iwata H, Ujiie H, Izumi K, Natsuga K, Nishie W, Asaka T, Kitagawa Y, Shimizu H.
- Journal Title
  
  Br J Dermatol.
  
  Volume: 178 Issue: 2 Pages: e119-e121
- DOI
  10.1111/bjd.15925
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
[Journal Article] Portable negative-pressure wound therapy for pyoderma gangrenosum: Report of two cases2018
- Author(s)
  Yamaguchi Y, Yanagi T, Sato K, Yoshimoto N, Hirata Y, Ujiie I, Nishimura M, Natsuga K, Shiiya C, Tsukinaga I, Shimizu H
- Journal Title
  
  J Dermatol
  
  Volume: 印刷中 Issue: 4 Pages: 483-486
- DOI
  10.1111/1346-8138.14180
- NAID
  120006600950
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Extensive Eruptive Syringoma After Liver Transplantation2018
- Author(s)
  Maeda T、Natsuga K、Nishie W、Yamashita K、Shimizu H
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 98 Issue: 1 Pages: 119-120
- DOI
  10.2340/00015555-2814
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Epidermal aspects of type VII collagen: Implications for dystrophic epidermolysis bullosa and epidermolysis bullosa acquisita2018
- Author(s)
  Watanabe Mika、Natsuga Ken、Shinkuma Satoru、Shimizu Hiroshi
- Journal Title
  
  The Journal of Dermatology
  
  Volume: 45 Issue: 5 Pages: 515-521
- DOI
  10.1111/1346-8138.14222
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01572, KAKENHI-PROJECT-17H05089, KAKENHI-PROJECT-17K16317
[Journal Article] Life before and beyond blistering: The role of collagen XVII in epidermal physiology2018
- Author(s)
  Natsuga K, Watanabe M, Nishie W, Shimizu H
- Journal Title
  
  Exp Dermatol
  
  Volume: 印刷中 Issue: 10 Pages: 1135-1141
- DOI
  10.1111/exd.13550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Regulatory T-cell dysfunction induces autoantibodies to bullous pemphigoid antigens in mice and human subjects2018
- Author(s)
  Muramatsu Ken、Ujiie Hideyuki、Kobayashi Ichiro、Nishie Wataru、Izumi Kentaro、Ito Takamasa、Yoshimoto Norihiro、Natsuga Ken、Iwata Hiroaki、Shimizu Hiroshi
- Journal Title
  
  Journal of Allergy and Clinical Immunology
  
  Volume: 142 Issue: 6 Pages: 1818-1830.e6
- DOI
  10.1016/j.jaci.2018.03.014
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Sweet's Syndrome Mimicking Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis2018
- Author(s)
  Kosumi H, Watanabe M, Natsuga K, Miyauchi T, Shiiya C, Ujiie H, Shimizu H
- Journal Title
  
  Am J Med
  
  Volume: 印刷中 Issue: 6 Pages: e241-e242
- DOI
  10.1016/j.amjmed.2017.12.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] The direct binding of collagen XVII and collagen IV is disrupted by pemphigoid autoantibodies2018
- Author(s)
  Kamaguchi Mayumi、Iwata Hiroaki、Nishie Wataru、Toyonaga Ellen、Ujiie Hideyuki、Natsuga Ken、Kitagawa Yoshimasa、Shimizu Hiroshi
- Journal Title
  
  Laboratory Investigation
  
  Volume: 99 Issue: 1 Pages: 48-57
- DOI
  10.1038/s41374-018-0113-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-16K10141, KAKENHI-PROJECT-17K16317
[Journal Article] Acute vascular reaction due to lipo-prostaglandin E12018
- Author(s)
  Fujimura Y, Watanabe M, Natsuga K, Shimizu H
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 印刷中 Issue: 7
- DOI
  10.1111/jdv.14807
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Loss of interaction between plectin and type XVII collagen results in epidermolysis bullosa simplex2017
- Author(s)
  Natsuga K, Nishie W, Nishimura M, Shinkuma S, Watanabe M, Izumi K, Nakamura H, Hirako Y, Shimizu H
- Journal Title
  
  Hum Mutat
  
  Volume: 38 Issue: 12 Pages: 1666-1670
- DOI
  10.1002/humu.23344
- NAID
  120006540047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K10207, KAKENHI-PROJECT-17K16317
[Journal Article] Appearance of antidesmocollin 1 autoantibodies leading to a vegetative lesion in a patient with pemphigus vulgaris2017
- Author(s)
  Yamaguchi Y.、Shinkuma S.、Ishii N.、Takashima S.、Natsuga K.、Ujiie H.、Iwata H.、Nomura T.、Fujita Y.、Hamasaka A.、Hamasaka K.、Hashimoto T.、Shimizu H.
- Journal Title
  
  Br J Dermatol
  
  Volume: 178 Issue: 1 Pages: 294-295
- DOI
  10.1111/bjd.15834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Crusted impetigo-like eruption on the face: A case report of IgG/IgA pemphigus2017
- Author(s)
  Moriuchi R, Ito T, Kikuchi K, Nakashita N, Muramatsu R, Natsuga K, Shimizu H, Shimizu S
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 印刷中 Issue: 6
- DOI
  10.1111/jdv.14060
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Psoriasiform mycosis fungoides masquerading as tumourous plaques2017
- Author(s)
  Yamaguchi Y, Fujita Y, Hirata Y, Nishimura M, Shinkuma S, Natsuga K, Hida T, Kato N, Shimizu H
- Journal Title
  
  Eur J Dermatol
  
  Volume: 印刷中 Issue: 3 Pages: 295-296
- DOI
  10.1684/ejd.2017.2971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-17K16317
[Journal Article] Generalized Pustular Psoriasis2017
- Author(s)
  Kosumi Hideyuki、Ito Takamasa、Fujita Yasuyuki、Izumi Kentaro、Maya Yuka、Yanagi Teruki、Natsuga Ken、Ujiie Hideyuki、Shinkuma Satoru、Nomura Toshifumi、Sadanobu Naoya、Shimizu Hiroshi
- Journal Title
  
  J Pediatr
  
  Volume: 188 Pages: 305-305.e1
- DOI
  10.1016/j.jpeds.2017.05.058
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Autoantibodies of non-inflammatory bullous pemphigoid hardly deplete type XVII collagen of keratinocytes2017
- Author(s)
  Imafuku K, Iwata H, Kamaguchi M, Izumi K, Natsuga K, Ujiie H, Nishie W, Shimizu H
- Journal Title
  
  Exp Dermatol
  
  Volume: 印刷中 Issue: 12 Pages: 1171-1174
- DOI
  10.1111/exd.13331
- NAID
  120006540054
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-17K16317
[Journal Article] 出生前診断2017
- Author(s)
  夏賀　健
- Journal Title
  
  Visual Dermatology
  
  Volume: 16 Pages: 276-277
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] C-Terminal Processing of Collagen XVII Induces Neoepitopes for Linear IgA Dermatosis Autoantibodies2017
- Author(s)
  Toyonaga Ellen、Nishie Wataru、Izumi Kentaro、Natsuga Ken、Ujiie Hideyuki、Iwata Hiroaki、Yamagami Jun、Hirako Yoshiaki、Sawamura Daisuke、Fujimoto Wataru、Shimizu Hiroshi
- Journal Title
  
  Journal of Investigative Dermatology
  
  Volume: 137 Issue: 12 Pages: 2552-2559
- DOI
  10.1016/j.jid.2017.07.831
- NAID
  120006540048
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K10207, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-26293254, KAKENHI-PROJECT-16H05365, KAKENHI-PROJECT-16K15539, KAKENHI-PROJECT-16K15541, KAKENHI-PROJECT-15KK0289
[Journal Article] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation in the COL7A1 gene2017
- Author(s)
  Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
- Journal Title
  
  J Dermatol Sci
  
  Volume: 88 Issue: 1 Pages: 139-141
- DOI
  10.1016/j.jdermsci.2017.03.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16K15540
[Journal Article] Early severe pachyonychia congenita subtype PC-K6a with a novel mutation in the KRT6A gene2017
- Author(s)
  Cammarata-Scalisi F, Natsuga K, Toyonaga E, Nishie W, Shimizu H, Avendano A, Araque D, Da Silva G, Bellacchio E, Callea M
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 31 Issue: 2
- DOI
  10.1111/jdv.13800
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation in the COL7A1 gene2017
- Author(s)
  Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
- Journal Title
  
  J Dermatol Sci
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Lichenoid drug eruption caused by clonazepam2017
- Author(s)
  Muramatsu K, Ujiie H, Natsuga K, Nishie W, Shimizu H
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 31 Issue: 2
- DOI
  10.1111/jdv.13862
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Type XVII collagen coordinates proliferation in the interfollicular epidermis.2017
- Author(s)
  Watanabe M, Natsuga K, Nishie W, Kobayashi Y, Donati G, Suzuk Si, Fujimura Y, Tsukiyama T, Ujiie H, Shinkuma S, Nakamura H, Murakami M, Ozaki M, Nagayama M, Watt F and Shimizu H
- Journal Title
  
  eLife
  
  Volume: 6:e26635 Pages: 1-24
- DOI
  10.7554/elife.26635
- NAID
  120006337772
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-16H03949, KAKENHI-PROJECT-17H04022
[Journal Article] Cutis Verticis Gyrata Fluctuation with Atopic Dermatitis Disease Activity2017
- Author(s)
  Kosumi H、Izumi K、Natsuga K、Yamaguchi Y、Itami A、Shimizu H
- Journal Title
  
  Acta Derm Venereol
  
  Volume: 97 Issue: 10 Pages: 1245-1246
- DOI
  10.2340/00015555-2750
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K16317
[Journal Article] Detection of mucous membrane pemphigoid autoantibodies by full-length BP180 enzyme-linked immunosorbent assay2017
- Author(s)
  Izumi Kentaro、Nishie Wataru、Mai Yosuke、Ujiie Hideyuki、Iwata Hiroaki、Natsuga Ken、Shimizu Hiroshi
- Journal Title
  
  J Dermatol Sci
  
  Volume: 88 Issue: 2 Pages: 247-248
- DOI
  10.1016/j.jdermsci.2017.07.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16317, KAKENHI-PROJECT-17K16318, KAKENHI-PROJECT-16H05365, KAKENHI-PROJECT-16K15539, KAKENHI-PROJECT-15KK0289
[Journal Article] Mucocutaneous pyoderma gangraenosum due to trisomy 8 neutrophilic infiltrates in a patient with myelodysplastic syndrome2016
- Author(s)
  Haga N, Iwata H, Yamaguchi Y, Shirato T, Nishimura K, Yamane N, Shinkuma S, Natsuga K, Kondo T, Shimizu H
- Journal Title
  
  Br J Dermatol
  
  Volume: 174 Issue: 1 Pages: 239-241
- DOI
  10.1111/bjd.14102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Autoantibody profile differentiates between inflammatory and noninflammatory bullous pemphigoid.2016
- Author(s)
  Izumi K, Nishie W, Mai Y, Wada M, Natsuga K, Ujiie H, Iwata H, Yamagami J, Shimizu H
- Journal Title
  
  J Invest Dermatol
  
  Volume: 136 Issue: 11 Pages: 2201-2210
- DOI
  10.1016/j.jid.2016.06.622
- NAID
  120006360054
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-16H05365, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-16K15539
[Journal Article] Extensive Erythema and Hyperkeratosis on the Extremities and Lumbar Area as an Unusual Mani-festation of Nagashima-type Palmoplantar Keratosis2016
- Author(s)
  Miyauchi T, Nomura T, Suzuki S, Ohguchi Y, Yamaguchi Y, Shinkuma S, Natsuga K, Fujita Y, Shimizu H.
- Journal Title
  
  Acta Dermato-Venereologica
  
  Volume: in press Pages: 856-858
- DOI
  10.2340/00015555-2391
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09738, KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-15K19668
[Journal Article] Verrucous hyperplasia associated with neuropathy from schistorrhachis2016
- Author(s)
  Imafuku K, Hata H, Inamura Y, Kitamura S, Natsuga K, Iwata H, Shimizu H
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 30 Issue: 5 Pages: 876-878
- DOI
  10.1111/jdv.13042
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Macropinocytosis of type XVII collagen induced by bullous pemphigoid IgG is regulated via protein kinase C2016
- Author(s)
  Iwata H, Ujiie H, Nishimura M, Izumi K, Natsuga K, Shinkuma S, Nishie W, Shimizu H
- Journal Title
  
  Lab Invest
  
  Volume: 96 Issue: 12 Pages: 1301-1310
- DOI
  10.1038/labinvest.2016.108
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Metal implant-induced skin ulcer mimicking scrofuloderma2016
- Author(s)
  Kitamura S, Natsuga K*, Imafuku K, Homma E, Yamane N, Aoyagi S, Matsumura T, Shimizu H
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 30 Issue: 3 Pages: 449-450
- DOI
  10.1111/jdv.12825
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Nodular morphoea: a first case associated with linear morphoea2016
- Author(s)
  Nakazato S, Nomura T, Yamane N, Shinkuma S, Natsuga K, Fujita Y, Arita K, Shimizu H
- Journal Title
  
  Eur J Dermatol
  
  Volume: 26 Issue: 1 Pages: 95-96
- DOI
  10.1684/ejd.2015.2656
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H04780, KAKENHI-PROJECT-25461681, KAKENHI-PROJECT-15K19668
[Journal Article] Stem cell markers of skin appendages in human skin tumours2016
- Author(s)
  Natsuga K
- Journal Title
  
  Br J Dermatol
  
  Volume: 175 Issue: 3 Pages: 459-459
- DOI
  10.1111/bjd.14655
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Silicone medical adhesive removers for hyperkeratosis in epidermolysis bullosa2016
- Author(s)
  Fujita Y, Shinkuma S, Matsumura W, Natsuga K, Hata H, Nomura T, Shimizu H
- Journal Title
  
  Eur J Dermatol
  
  Volume: 26 Issue: 5 Pages: 501-502
- DOI
  10.1684/ejd.2016.2817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Epitope-dependent pathogenicity of Abs targeting a major bullous pemphigoid autoAg collagen XVII/BP1802016
- Author(s)
  Wada M, Nishie W*, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H:
- Journal Title
  
  J Invest Dermatol
  
  Volume: 136 Pages: 938-946
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K10120
[Journal Article] Pyoderma gangrenosum associated with acute respiratory distress syndrom2016
- Author(s)
  Watanabe M, Natsuga K, Ota M, Ito K
- Journal Title
  
  Am J Med
  
  Volume: 129 Issue: 2 Pages: e17-e18
- DOI
  10.1016/j.amjmed.2015.08.035
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Increased bacterial load and expression of antimicrobial peptides in skin of barrier-deficient mice with reduced cancer susceptibility2016
- Author(s)
  Natsuga K, Cipolat S, Watt FM
- Journal Title
  
  J Invest Dermatol
  
  Volume: 136 Issue: 1 Pages: 99-106
- DOI
  10.1038/jid.2015.383
- NAID
  120005822527
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Epidermolysis bullosa acquisita develops in dominant dystrophic epidermolysis bullosa2016
- Author(s)
  Hayashi R, Natsuga K, Watanabe M, Iwata H, Shinkuma S, Ito A, Masui Y, Ito M, Shimomura Y
- Journal Title
  
  J Invest Dermatol
  
  Volume: 136 Issue: 1 Pages: 320-323
- DOI
  10.1038/jid.2015.370
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Concomitant neoplasms in skin and stomach unveil the role of type IV collagen and E-cadherin in MUC5AC expression in vivo2016
- Author(s)
  Hata H, Natsuga K, Kitamura S, Imafuku K, Yamaguchi Y, Ebihara Y, Shichinohe T, Hirano S, Shimizu H
- Journal Title
  
  Br J Dermatol
  
  Volume: 174 Issue: 2 Pages: 395-397
- DOI
  10.1111/bjd.14084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Anti-laminin-gamma 1 pemphigoid with generalized pustular psoriasis and psoriasis vulgaris2016
- Author(s)
  Fujimura Y, Natsuga K*, Hamade Y, Nomura Y, Kaku Y, Muramatsu R, Shimizu H
- Journal Title
  
  Acta Dermato-Venereol
  
  Volume: 96 Issue: 1 Pages: 120-121
- DOI
  10.2340/00015555-2168
- NAID
  120005722550
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] mTOR expression correlates with invasiveness and progression of extramammary Paget's disease2016
- Author(s)
  Hata H, Kitamura S, Inamura Y, Imafuku K, Homma E, Muramatsu K, Natsuga K, Abe R, Shimizu H
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 30 Issue: 7 Pages: 1238-1239
- DOI
  10.1111/jdv.13168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Extracellular cleavage of collagen XVII is essential for correct cutaneous basement membrane formation.2016
- Author(s)
  Nishimura M, Nishie W, Shirafuji Y, Shinkuma S, Natsuga K, Nakamura H, Sawamura D, Iwatsuki K, Shimizu H
- Journal Title
  
  Hum Mol Genet
  
  Volume: 15;25(2) Issue: 2 Pages: 328-39
- DOI
  10.1093/hmg/ddv478
- NAID
  120005868259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-15K15409, KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-26293254, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-16K10120, KAKENHI-PROJECT-15KK0289
[Journal Article] Galectin-6 is a novel skin anti-microbial peptide that is modulated by the skin barrier and microbiome2016
- Author(s)
  Natsuga K, Watt FM
- Journal Title
  
  J Dermatol Sci
  
  Volume: 84 Issue: 1 Pages: 97-99
- DOI
  10.1016/j.jdermsci.2016.06.008
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Epitope-Dependent Pathogenicity of Antibodies Targeting a Major Bullous Pemphigoid Autoantigen Collagen XVII/BP180.2016
- Author(s)
  Wada M, Nishie W, Ujiie H, Izumi K, Iwata H, Natsuga K, Nakamura H, Kitagawa Y, Shimizu H
- Journal Title
  
  J Invest Dermatol
  
  Volume: in press Issue: 5 Pages: 938-946
- DOI
  10.1016/j.jid.2015.11.030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-15K19668
[Journal Article] Mucosal hyperpigmentation from prophylactic minocycline for EGFR inhibitor2016
- Author(s)
  Imafuku K, Natsuga K*, Aoyagi S, Shimizu H
- Journal Title
  
  J Eur Acad Dermatol Venereol
  
  Volume: 30 Issue: 4 Pages: 690-692
- DOI
  10.1111/jdv.12978
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Two cases of erosive oral lichen planus with non-pathogenic autoantibodies to desmoglein 32016
- Author(s)
  Muramatsu K, Nishie W, Natsuga K, Fujita Y, Iwata H, Yamada T, Yamashita E, Asaka T, Shimizu H
- Journal Title
  
  J Dermatol
  
  Volume: 43 Issue: 11 Pages: 1350-1353
- DOI
  10.1111/1346-8138.13493
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Anti-BP180-type mucous membrane pemphigoid: Report of two cases2016
- Author(s)
  Wada M, Sato J, Shindoh M, Ujiie H, Natsuga K, Nishie W, Shimizu H, Kitagawa Y
- Journal Title
  
  Odontology
  
  Volume: 104 Issue: 1 Pages: 114-118
- DOI
  10.1007/s10266-014-0181-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Context-Dependent Regulation of Collagen XVII Ectodomain Shedding in Skin.2015
- Author(s)
  Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, Nakamura H, Shimizu H.
- Journal Title
  
  Am J Pathol
  
  Volume: in press Issue: 5 Pages: 1361-71
- DOI
  10.1016/j.ajpath.2015.01.012
- NAID
  120005752843
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-25461661, KAKENHI-PROJECT-26670516, KAKENHI-PROJECT-15K19668
[Journal Article] Bowen’s disease on the palm presents refractory skin erosion without erythematous plaque2015
- Author(s)
  Kitamura S, Iwata H, Imafuku K, Hata H, Natsuga K, Aoyagi S, Shimizu H
- Journal Title
  
  J Dermatol
  
  Volume: 42 Issue: 2 Pages: 225-6
- DOI
  10.1111/1346-8138.12745
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Plectin-related skin diseases2015
- Author(s)
  Natsuga K
- Journal Title
  
  J Dermatol Sci
  
  Volume: 77 Issue: 3 Pages: 139-45
- DOI
  10.1016/j.jdermsci.2014.11.005
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668
[Journal Article] Generalized acute subcutaneous edema as a rare cutaneous manifestation of severe dermatomyositis.2015
- Author(s)
  Watanabe M, Natsuga K, Arita K, Abe R, Shimizu H.
- Journal Title
  
  Journal of European Academy of Dermatology and Venereology
  
  Volume: in press Issue: 11
- DOI
  10.1111/jdv.13460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461681, KAKENHI-PROJECT-15K19668
[Journal Article] Plasma cell cheilitis extending beyond vermillion border2015
- Author(s)
  Fujimura Y, Natsuga K*, Abe R, Morita Y, Nomura T, Shimizu H
- Journal Title
  
  J Dermatol
  
  Volume: 42 Issue: 9 Pages: 935-6
- DOI
  10.1111/1346-8138.12985
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-15H04780
[Journal Article] Context-Dependent Regulation of Collagen XVII Ectodomain Sheddingin Skin.2015
- Author(s)
  Nishie W, Natsuga K, Iwata H, Izumi K, Ujiie H, Toyonaga E, Hata H, NakamuraH, Shimizu H
- Journal Title
  
  Am J Pathol
  
  Volume: 185(5) Pages: 1361-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25461661
[Journal Article] In vivo analysis of IgE autoantibodies in bullous pemphigoid: A study of 100 cases.2015
- Author(s)
  Moriuchi R, Nishie W, Ujiie H, Natsuga K, Shimizu H.
- Journal Title
  
  J Dermatol Sci
  
  Volume: 78 Issue: 1 Pages: 21-25
- DOI
  10.1016/j.jdermsci.2015.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390274, KAKENHI-PROJECT-26670516, KAKENHI-PROJECT-15K19668
[Journal Article] Skipped exon in COL7A1 determines the clinical phenotypes of dystrophic epidermolysis bullosa.2015
- Author(s)
  Toyonaga E, Nishie W, Komine M, Murata S, Shinkuma S, Natsuga K, Nakamura H, Ohtsuki M, Shimizu H.
- Journal Title
  
  British Journal of Dermatology
  
  Volume: 172 Issue: 4 Pages: 1141-1144
- DOI
  10.1111/bjd.13386
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-25461661
[Journal Article] Non-solar-induced elastotic bands on the forearm2015
- Author(s)
  Haga N, Abe R, Morita Y, Fujimura Y, Natsuga K, Nomura T, Kumakiri M, Shimizu H
- Journal Title
  
  Eur J Dermatol
  
  Volume: 25 Issue: 5 Pages: 508-9
- DOI
  10.1684/ejd.2015.2629
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19668, KAKENHI-PROJECT-15H04780
[Journal Article] Bullous Pemphigoid Autoantibodies Directly Induce Blister Formation without Complement Activation.2014
- Author(s)
  Ujiie H, Sasaoka T, Izumi K, Nishie W, Shinkuma S, Natsuga K, Nakamura H, Shibaki A, Shimizu H
- Journal Title
  
  The Journal of Immunology
  
  Volume: 193 Issue: 9 Pages: 4415-4428
- DOI
  10.4049/jimmunol.1400095
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25461661
[Journal Article] Dermoscopic Features of Plasma Cell Cheilitis and Actinic Cheilitis2014
- Author(s)
  Ito T, Natsuga K, Tanimura S, Aoyagi S, Shimizu H
- Journal Title
  
  Acta Derm Venereol
  
  Volume: (in press) Issue: 5 Pages: 593-594
- DOI
  10.2340/00015555-1795
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Ultrasound B-mode and Elastographic Findings of Angiomatoid Fibrous Histiocytoma2014
- Author(s)
  Hata H, Natsuga K, Homma E, Aoyagi S, Shimizu H
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Paper-Based ELISA for the Detection of Autoimmune Antibodies in Body Fluid-The Case of Bullous Pemphigoid2014
- Author(s)
  Hsu CK, Huang HY, Chen WR, Nishie W, Ujiie H, Natsuga K, Fan ST, Wang HK, Lee JY, Tsai WL, Shimizu H, Cheng CM
- Journal Title
  
  Anal Chem
  
  Volume: (in press) Issue: 9 Pages: 4605-4610
- DOI
  10.1021/ac500835k
- Year and Date
  2014-04-27
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Epidermal Wnt/beta-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors2014
- Author(s)
  Donati G, Proserpio V, Lichtenberger BM, Natsuga K, Sinclair R, Fujiwara H, Watt FM
- Journal Title
  
  Proc Natl Acad Sci U S A
  
  Volume: 111 Issue: 15
- DOI
  10.1073/pnas.1312880111
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494, KAKENHI-PUBLICLY-25122720
[Journal Article] Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility2014
- Author(s)
  Cipolat S, Hoste E, Natsuga K, Quist S, Watt FM
- Journal Title
  
  eLife
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Epidermal Barriers2014
- Author(s)
  Natsuga K
- Journal Title
  
  Cold Spring Harb Perspect Med
  
  Volume: 4 Issue: 4 Pages: a018218-a018218
- DOI
  10.1101/cshperspect.a018218
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] c-MYC-induced sebaceous gland differentiation is controlled by an androgen receptor/p53 axis2013
- Author(s)
  Cottle DL, Kretzschmar K, Schweiger PJ, Quist SR, Gollnick HP, Natsuga K, Aoyagi S, Watt FM
- Journal Title
  
  Cell Rep
  
  Volume: 3 Issue: 2 Pages: 427-441
- DOI
  10.1016/j.celrep.2013.01.013
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Jacyk、Ken Natsuga、Hideyuki Ujiie、Hideki Nakamura、Masashi Akiyama、Hiroshi Shimizu2013
- Author(s)
  Satoru Shinkuma、Wataru Nishie、 Witold K
- Journal Title
  
  A Novel Keratin 5 Mutation in an African Family with Epidermolysis Bullosa Simplex Indicates the Importance of the Amino Acid Located at the Boundary Site Between the H1 and Coil 1A Domains
  
  Volume: 印刷中 Issue: 5 Pages: 585-587
- DOI
  10.2340/00015555-1538
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23890006, KAKENHI-PROJECT-24249062, KAKENHI-PROJECT-24659516, KAKENHI-PROJECT-24659526, KAKENHI-PROJECT-25670494
[Journal Article] Coexistence case of bullous pemphigoid and pemphigus foliaceus2013
- Author(s)
  Tsujiwaki M, Abe R, Nomura Y, Nishimura M, Hoshina D, Shinkuma S, Natsuga K, Ujiie H, Arita K, Shimizu H
- Journal Title
  
  Eur J Dermatol
  
  Volume: 23 Issue: 4 Pages: 552-553
- DOI
  10.1684/ejd.2013.2084
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Antibodies to pathogenic epitopes on type XVII collagen cause skin fragility in a complement-dependent and-independent manner2012
- Author(s)
  Natsuga K, Nishie W, et al.
- Journal Title
  
  J Immunol
  
  Volume: 188 Pages: 5792-9
- NAID
  10031131103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24390274
[Journal Article] Ultrasound B-mode and Elastographic Findings of Angiomatoid Fibrous Histiocytoma.
- Author(s)
  Hata H, Natsuga K, Homma E, Aoyagi S, Shimizu H
- Journal Title
  
  Clin Exp Dermatol
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Journal Article] Epidermal barrier defects link atopic dermatitis with altered skin cancer susceptibility
- Author(s)
  Cipolat S, Hoste E, Natsuga K, Quist S, Watt FM
- Journal Title
  
  eLife
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25670494
[Presentation] Conformational epitope mapping of autoantibodies against BP180 in dipeptidyl peptidase-4 inhibitors-associated bullous pemphigoid2023
- Author(s)
  Shoko Mai, Kentaro Izumi, Yosuke Mai, Ken Natsuga, Wataru Nishie, and Hideyuki Ujiie
- Organizer
  International Societies for Investigative Dermatology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02938
[Presentation] Type XVII collagen-specific CD4+ T cell clones induce bullous pemphigoid in mice by producing IL-52023
- Author(s)
  Norihiro Yoshimoto, Ken Muramatsu, Takamasa Ito, Zheng Miao, Kentaro Izumi, Ken Natsuga, Hiroaki Iwata, Yoshinori Hasegawa, Hiroshi Shimizu, Hideyuki Ujiie
- Organizer
  International Societies for Investigative Dermatology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02938
[Presentation] Aged mice produce IgM autoantibodies against the basement membrane zone2023
- Author(s)
  Chihiro Shiiya, Ken Muramatsu, Norihiro Yoshimoto, Sho Katayama, Takuya Kawamura, Shoko Mai, Yosuke Mai, Hiroyuki Kitahata, Ken Natsuga, Hiroaki Iwata, Kentaro Izumi, Hideyuki Ujiie
- Organizer
  International Societies for Investigative Dermatology 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02938
[Presentation] Type XVII collagen-specific CD4+ T cell clones induce the phenotype of bullous pemphigoid in mice by producing Th2 cytokines2022
- Author(s)
  Norihiro Yoshimoto, Ken Muramatsu, Takamasa Ito, Zheng Miao, Ken Natsuga, Wataru Nishie, Hiroaki Iwata, Yoshinori Hasegawa, Hiroshi Shimizu, Hideyuki Ujiie
- Organizer
  The 47th Annual Meeting of the Japanese Society for Investigative Dermatology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02938
[Presentation] 表皮の恒常性維持と外的刺激に対する応答2019
- Author(s)
  夏賀　健
- Organizer
  第1回炎症性皮膚疾患集中セミナー
- Invited
- Data Source
  KAKENHI-PROJECT-17K16317
[Presentation] Differences in collagen XVII expression between skin and oral mucosa affect the pathogenicity of pemphigoid IgG2018
- Author(s)
  .Kamaguchi M, Iwata H, Ujiie H, Natsuga K, Nishie W, Asaka T, Shimizu H, Kitagawa Y.
- Organizer
  14th Biennial Congress of the European Association of Oral Medicine Gotenbrug, Sweden.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10120
[Presentation] Clavus serves as a model of epidermal stem cell responses to mechanical forces2018
- Author(s)
  Natsuga K, Watanabe M, Hata H, Kobayashi Y, Nagayama M, Shimizu H
- Organizer
  International Investigative Dermatology 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16317
[Presentation] 表皮化水疱症　発症機序/新規治療法の最新の進歩2018
- Author(s)
  夏賀　健
- Organizer
  第117回日本皮膚科学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-17K16317
[Presentation] Organization of the epidermal basement membrane zone determined through super-resolution microscopy2018
- Author(s)
  Natsuga K, Watanabe M, Shimizu H
- Organizer
  7th SSSR and SCUR meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16317
[Presentation] Abnormalities in laminin-332 have post-translational effects on laminin γ22017
- Author(s)
  Natsuga K, Nishie W, Watanabe M, Nakamura H, Shinkuma S, Shimizu H
- Organizer
  EB2017 - 5th World Conference of EB Research & 4th Conference of EB-CLINET
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16317
[Presentation] Abnormalities in laminin-332 have post-translational effects on laminin γ22017
- Author(s)
  Natsuga K, Nishie W, Watanabe M, Nakamura H, Shinkuma S, Shimizu H
- Organizer
  EB2017 - 5th World Conference of EB Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10120
[Presentation] A case of recessive dystrophic epidermolysis bullosa with a novel c.6885_6898del14 mutation.2017
- Author(s)
  Shinkuma S, Masunaga T, Miyawaki S, Takashima S, Natsuga K, Nomura T, Fujita Y, Nakamura H, Shimizu H
- Organizer
  The 76th Annual Meeting of the Society for Investigative Dermatology.
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10120
[Presentation] Characterization of non-hemidesmosomal collagen XVII in basal keratinocytes2016
- Author(s)
  Natsuga K, Watanabe M, Nishie W, Shimizu H
- Organizer
  41th Annual Meeting of the Japanese Society for Investigative Dermatology (JSID)
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-12-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19668
[Presentation] 皮膚基底膜構築における17型コラーゲン細胞外領域切断の生理機能の解析2016
- Author(s)
  西村真智子, 西江渉, 新熊悟, 夏賀健, 中村秀樹, 白藤宜紀, 岩月啓氏, 澤村大輔, 清水宏
- Organizer
  第407回日本皮膚科学会北海道地方会
- Place of Presentation
  札幌医大、札幌市
- Data Source
  KAKENHI-PROJECT-16K10120
[Presentation] Defective binding of plectin and collagen XVII leads to epidermolysis bullosa simplex.2016
- Author(s)
  Natsuga K, Nihsie W, Nishimura M, Shinkuma S, Watanabe M, Izumi K, Nakamura H, Hirako Y, Shimizu H
- Organizer
  The 46th Annual European Society for Dermatological Research meeting.
- Place of Presentation
  Technical University of Munich, Munich, Germany
- Year and Date
  2016-09-07
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10120
[Presentation] Organization of the Basement Membrane Zone: Implications for Epidermolysis Bullosa2016
- Author(s)
  Natsuga K
- Organizer
  第115回日本皮膚科学会総会
- Place of Presentation
  京都国際会館（京都府京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K19668
[Presentation] 表皮細胞の分化・増殖における基底膜の役割2016
- Author(s)
  夏賀　健
- Organizer
  第115回日本皮膚科学会総会
- Place of Presentation
  京都国際会館（京都府京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K19668
[Presentation] アトピー性皮膚炎/魚鱗癬における細菌叢と抗菌ペプチド2016
- Author(s)
  夏賀　健
- Organizer
  第115回日本皮膚科学会総会
- Place of Presentation
  京都国際会館（京都府京都市）
- Invited
- Data Source
  KAKENHI-PROJECT-15K19668
[Presentation] 全長XVII型コラーゲンを抗原としたELISAによる粘膜類天疱瘡患者自己抗体の検出2015
- Author(s)
  泉　健太郎、西江　渉、夏賀　健、岩田浩明、氏家英之、清水　宏
- Organizer
  第37回水疱症研究会
- Place of Presentation
  コラッセ福島、福島市
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-24390274
[Presentation] A single laminin subunit deficiency alters other laminin expression depending on the mutated genes.2015
- Author(s)
  Natsuga K, Nishie W, Shinkuma S, Nakamura H, Watanabe M, Kambe M, Hatamochi A, Kimura U, Suga Y, Shimizu H
- Organizer
  The 40th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okayama convention center, Okayama, Okayama-City
- Year and Date
  2015-12-11
- Data Source
  KAKENHI-PROJECT-25461661
[Presentation] A single laminin subunit deficiency alters other laminin expression depending on the mutated genes2015
- Author(s)
  Natsuga K, Nishie W, Shinkuma S, Nakamura H, Watanabe M, Kambe N, Hatamochi A, Kimura U, Suga Y, Shimizu H
- Organizer
  40th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Okayama, Japan
- Year and Date
  2015-12-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19668
[Presentation] 全長XVII型コラーゲンを抗原としたELISAによる粘膜類天疱瘡患者自己抗体の検出2015
- Author(s)
  泉　健太郎、西江　渉、夏賀　健、岩田浩明、氏家英之、清水　宏
- Organizer
  第37回水疱症研究会
- Place of Presentation
  コラッセ福島、福島県、福島市
- Year and Date
  2015-09-26
- Data Source
  KAKENHI-PROJECT-15K15409
[Presentation] Pathogenetic mechanisms in autoimmune skin fragility2013
- Author(s)
  Natsuga K
- Organizer
  The 40th Annual Meeting of Society for Cutaneous Ultrastructure Research
- Place of Presentation
  Castellani Parkhotel Salzburg (Austria)
- Invited
- Data Source
  KAKENHI-PROJECT-25670494
[Presentation] Skin barrier defect allows more abundant microbiota in skin and induces skin inflammation and the expression of antimicrobial peptides independently of microbiota : Skin barrier defect allows more abundant microbiota in skin and induces skin inflammation and the expression of antimicrobial peptides independently of microbiota.2013
- Author(s)
  Natsuga K, Cipolat S, Watt FM
- Organizer
  The International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh, Scotland
- Data Source
  KAKENHI-PROJECT-25670494
[Presentation] Pathogenetic mechanisms in autoimmune skin fragility.2013
- Author(s)
  Natsuga K
- Organizer
  The 40th Annual Meeting of Society for Cutaneous Ultrastructure Research
- Place of Presentation
  Salzburg, Austria
- Invited
- Data Source
  KAKENHI-PROJECT-25670494
[Presentation] Essential role of collagen XVII in basement membrane formation and keratinocyte migration.2013
- Author(s)
  Nishimura M, Nihsie W, Shinkuma S, Natsuga K, Nakamura H, Sawamura D, Iwatsuki K, Shimizu H
- Organizer
  The International Investigative Dermatology
- Place of Presentation
  Edinburgh International Conference Centre (Scotland)
- Data Source
  KAKENHI-PROJECT-25461661
[Presentation] Skin barrier defect allows more abundant microbiota in skin and induces skin inflammation and the expression of antimicrobial peptides independently of microbiota2013
- Author(s)
  Natsuga K, Cipolat S, Watt FM
- Organizer
  International Investigative Dermatology 2013
- Place of Presentation
  Edinburgh International Conference Centre (UK)
- Data Source
  KAKENHI-PROJECT-25670494
[Presentation] One amino acid deletion in type XII collagen-binding domain of plectin with a truncation mutation underlies epidermolysis bullosa simplex.
- Author(s)
  Natsuga K, Nishie W, Nishimura M, Nakamura H, Shimizu H.
- Organizer
  The 39th Annual Meeting of the Japanese Society of Invesitigative Dermatology
- Place of Presentation
  ホテル阪急エキスポパーク（吹田市）
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-26670516
[Presentation] Context-dependent tight regulation of collagen XVII ectodomain shedding in skin.
- Author(s)
  Nishie W, Natsuga K, Izumi K, Ujiie H, Hata H, Nakamura H, Shimizu H
- Organizer
  The 39th Annual Meeting of the Japanese Society of Invesitigative Dermatology
- Place of Presentation
  ホテル阪急エキスポパーク（吹田市）
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-24390274
[Presentation] One amino acid deletion in collagen XVII-binding domain of plectin with a truncation mutation underlies epidermolysis bullosa simplex.
- Author(s)
  Natsuga K, Nishimura M, Nakamura H, Nihsie W, Shimizu H
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Hotel Hankyu Expo Park, Osaka, Suita-City
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25461661
[Presentation] Context-dependent tight regulation of collagen XVII ectodomain shedding in skin.
- Author(s)
  Nihsie W, Natsuga K, Izumi K, Hata H, Nakamura H, Shimizu H
- Organizer
  The 39th Annual Meeting of the Japanese Society for Investigative Dermatology
- Place of Presentation
  Hotel Hankyu Expo Park, Osaka, Suita-City
- Year and Date
  2014-12-12 – 2014-12-14
- Data Source
  KAKENHI-PROJECT-25461661

1. Nishie Wataru (20443955)

# of Collaborated Projects: 9 results

# of Collaborated Products: 24 results
2. UJIIE HIDEYUKI (60374435)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
3. SHIMIZU Hiroshi (00146672)

# of Collaborated Projects: 4 results

# of Collaborated Products: 27 results
4. 岩田浩明 (20397334)

# of Collaborated Projects: 3 results

# of Collaborated Products: 7 results
5. 泉健太郎 (50793668)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
6. Nakamura Hideki (60435956)

# of Collaborated Projects: 2 results

# of Collaborated Products: 16 results
7. Watanabe Mika

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
8. Fujimura Yu

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
9. SHINKUMA SATORU (00613788)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. Fujita Yasuyuki (80374437)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 乃村俊史 (50399911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. 柳輝希 (50755973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 眞井洋輔 (00972308)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 長山雅晴 (20314289)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 高島翔太 (60962800)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. MATSUMURA WAKANA

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. NAKAYAMA CHIHIRO

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. TOYONAGA ellen

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. ARITA Ken

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 平子善章

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 築山忠維

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Natsuga Ken 夏賀 健

NATSUGA Ken 夏賀 健

Research Projects

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Co-Researchers

Identifying and overcoming factors contributing to delayed wound healing in epidermolysis bullosa.Principal Investigator

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Dynamics of epithelial stem cells upon woundingPrincipal Investigator

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Prevention of autoantigen depletion for bullous pemphigoid treatmentPrincipal Investigator

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[Book] Current Genetics in Dermatology2013

Author(s)

Natsuga Ken 夏賀健

NATSUGA Ken 夏賀健