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Ubukawa Kumi  小松 久美

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… Alternative Names

鵜生川久美

UBUKAWA Kumi  鵜生川 久美

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Researcher Number 70646554
Affiliation (based on the past Project Information) *help 2019 – 2021: 秋田大学, 医学系研究科, 講師
2018: 秋田大学, 医学部附属病院, 助教
2013 – 2017: 秋田大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Hematology / Basic Section 54010:Hematology and medical oncology-related
Except Principal Investigator
Basic Section 54010:Hematology and medical oncology-related
Keywords
Principal Investigator
脱核 / Cdc42 / ヒト赤芽球 / ダイニン / 赤血球造血 / CASIN / CASIN(阻害剤) / TRL4 / LPS / 好中球 … More / 造血幹細胞 / 微小管形成中心(MTOC) / EHNA(阻害剤) / 微小管形成中心(MTOC) / EHNA(阻害剤) / mDia2 / 細胞極性 / 中心体 / 赤芽球 … More
Except Principal Investigator
標的治療 / ゲノム編集 / 機能解析 / 遺伝子変異 / 免疫抑制療法 / 体細胞変異 / 骨髄系腫瘍関連遺伝子 / 再発・難治性 / 後天性赤芽球癆 Less
  • Research Projects

    (4 results)
  • Research Products

    (15 results)
  • Co-Researchers

    (5 People)
  •  後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発

    • Principal Investigator
      廣川 誠
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Akita University
  •  The mechanism of organelle relocation in human erythroblasts.Principal Investigator

    • Principal Investigator
      Ubukawa Kumi
    • Project Period (FY)
      2018 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 54010:Hematology and medical oncology-related
    • Research Institution
      Akita University
  •  The mechanism for determining the position of contraction ring formation in human erythroblast enucleation.Principal Investigator

    • Principal Investigator
      Ubukawa Kumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Akita University
  •  Human erythroblast enucleation requires dynein depependent cell polarization.Principal Investigator

    • Principal Investigator
      UBUKAWA Kumi
    • Project Period (FY)
      2013 – 2014
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Hematology
    • Research Institution
      Akita University

All 2021 2020 2019 2018 2016 2014

All Journal Article Presentation

  • [Journal Article] IL-6 Generated from Human Hematopoietic Stem and Progenitor Cells through TLR4 Signaling Promotes Emergency Granulopoiesis by Regulating Transcription Factor Expression2021

    • Author(s)
      Sasaki Yumi、Guo Yong-Mei、Goto Tatsufumi、Ubukawa Kumi、Asanuma Ken、Kobayashi Isuzu、Sawada Kenichi、Wakui Hideki、Takahashi Naoto
    • Journal Title

      The Journal of Immunology

      Volume: 207 Issue: 4 Pages: 1078-1086

    • DOI

      10.4049/jimmunol.2100168

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08315, KAKENHI-PROJECT-20K17367
  • [Journal Article] Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts2020

    • Author(s)
      Ubukawa Kumi、Goto Tatsufumi、Asanuma Ken、Sasaki Yumi、Guo Yong-Mei、Kobayashi Isuzu、Sawada Kenichi、Wakui Hideki、Takahashi Naoto
    • Journal Title

      Scientific Reports

      Volume: 10 Issue: 1 Pages: 11806-11806

    • DOI

      10.1038/s41598-020-68799-1

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] Thrombocytopenia Caused by a Tea Beverage of <i>Taxus yunnanensis</i> (Chinese Yew)2019

    • Author(s)
      Ubukawa K, Kameoka Y, Guo YM, Nara M, Watanabe A, Fujishima M, Fujishima N, Yoshioka T, Takahashi N.
    • Journal Title

      Intern. Med.

      Volume: 58 Issue: 21 Pages: 3153-3156

    • DOI

      10.2169/internalmedicine.2967-19

    • NAID

      130007740721

    • ISSN
      0918-2918, 1349-7235
    • Year and Date
      2019-11-01
    • Language
      English
    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] 1.ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts.2019

    • Author(s)
      Goto T, Ubukawa K, Kobayashi I, Sugawara K, Asanuma K, Sasaki Y, Guo YM, Takahashi N, Sawada K, Wakui H, Nunomura W.
    • Journal Title

      Exp Hematol.

      Volume: 72

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] The localization of α-synuclein in the process of differentiation of human erythroid cells2018

    • Author(s)
      Araki Katsuya、Sugawara Kotomi、Hayakawa Eri H.、Ubukawa Kumi、Kobayashi Isuzu、Wakui Hideki、Takahashi Naoto、Sawada Kenichi、Mochizuki Hideki、Nunomura Wataru
    • Journal Title

      International Journal of Hematology

      Volume: 108 Issue: 2 Pages: 130-138

    • DOI

      10.1007/s12185-018-2457-8

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K08315, KAKENHI-PROJECT-18K11135, KAKENHI-PROJECT-16K09716
  • [Journal Article] 赤血球脱核とその異常2018

    • Author(s)
      鵜生川久美
    • Journal Title

      血液フロンティア

      Volume: 28 Pages: 1315-1359

    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Journal Article] Erythroblast enucleation is a dynein-dependent process.2016

    • Author(s)
      Kobayashi I, Ubukawa K, Sugawara K, Asanuma K, Guo Y, Yamashita J, Takahashi N, Sawada K, Nunomura W.
    • Journal Title

      Exp. Hematol.

      Volume: 44 Issue: 4 Pages: 247-256

    • DOI

      10.1016/j.exphem.2015.12.003

    • Peer Reviewed / Acknowledgement Compliant / Open Access
    • Data Source
      KAKENHI-PROJECT-15K09448, KAKENHI-PROJECT-15K19540
  • [Journal Article] 赤芽球脱核の分子機構と血液疾患2014

    • Author(s)
      鵜生川久美、澤田賢一
    • Journal Title

      血液内科

      Volume: 68 Pages: 585-591

    • Data Source
      KAKENHI-PROJECT-25860777
  • [Journal Article] なぜ?どのように?赤芽球の脱核2014

    • Author(s)
      鵜生川久美
    • Journal Title

      血液フロンティア

      Volume: 24 Pages: 55-61

    • Data Source
      KAKENHI-PROJECT-25860777
  • [Presentation] Cdc42 regulates terminal differentiation in human erythroblasts.2018

    • Author(s)
      Goto T, Ubukawa K, Asanuma K, Kobayashi I, Guo YM, Takahashi N, Wakui H, Nunomura W.
    • Organizer
      第80回日本血液学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Presentation] ヒト赤芽球の終末分化におけるCdc42の情報伝達経路の解明.2018

    • Author(s)
      後藤樹史、鵜生川久美、浅沼研、小林五十鈴、郭永梅、高橋直人、涌井秀樹、布村渉
    • Organizer
      第91回日本生化学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K08315
  • [Presentation] 赤芽球におけるα-synuclein の発現と膜結合解析2016

    • Author(s)
      菅原琴美, 荒木克哉, 浅沼研, 早川枝李, 鵜生川久美, 小林五十鈴, 山下順助, 高橋直人, 涌井秀樹, 澤田賢一, 望月秀樹, 布村渉
    • Organizer
      日本膜学会第38年会
    • Place of Presentation
      早稲田大学 西早稲田キャンパス63号館 (新宿区)
    • Year and Date
      2016-05-10
    • Data Source
      KAKENHI-PROJECT-15K19540
  • [Presentation] Cdc42 regulates enucleation of human erythroblasts.2016

    • Author(s)
      Kumi Ubukawa, Tatsufumi Goto, Isuzu Kobayashi, Yong-Mei Guo, Ken Asanuma, Naoto Takahashi, Hideki Wakui & Wataru Nunomura.
    • Organizer
      The 2016 ASCB Meeting
    • Place of Presentation
      San Francisco (USA).
    • Year and Date
      2016-12-03
    • Data Source
      KAKENHI-PROJECT-15K19540
  • [Presentation] ヒドロキシクロロキンによる乳酸脱水素酵素の活性阻害と抗腫瘍効果の解析2016

    • Author(s)
      後藤樹史, 菅原琴美, 浅沼研, 小林五十鈴, 鵜生川久美, 郭永梅, 高橋直人, 涌井秀樹, 布村渉
    • Organizer
      日本生化学会東北支部会 第82回例会・シンポジウム
    • Place of Presentation
      弘前大学医学部・基礎大講堂(弘前市)
    • Year and Date
      2016-05-21
    • Data Source
      KAKENHI-PROJECT-15K19540
  • [Presentation] ヒト赤血球系細胞におけるα-synuclein の細胞内局在とリン脂質結合2016

    • Author(s)
      菅原琴美, 荒木克哉, 浅沼研, 早川枝李, 鵜生川久美, 小林五十鈴, 山下順助, 高橋直人, 涌井秀樹, 澤田賢一, 望月秀樹, 布村渉
    • Organizer
      第36回日本細胞生物学会・日本ケミカルバイオロジー学会第11回年会合同大会
    • Place of Presentation
      京都テルサ (京都市)
    • Year and Date
      2016-06-15
    • Data Source
      KAKENHI-PROJECT-15K19540
  • 1.  高橋 直人 (80344753)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 6 results
  • 2.  廣川 誠 (50241667)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  久場 敬司 (10451915)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  石田 文宏 (80311695)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  NUNOMURA Wataru
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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