Ubukawa Kumi 小松久美

… Alternative Names

鵜生川久美

UBUKAWA Kumi 鵜生川久美

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Researcher Number	70646554
Affiliation (based on the past Project Information) *help	2019 – 2021: 秋田大学, 医学系研究科, 講師 2018: 秋田大学, 医学部附属病院, 助教 2013 – 2017: 秋田大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 脱核 / Cdc42 / ヒト赤芽球 / ダイニン / 赤血球造血 / CASIN / CASIN（阻害剤） / TRL4 / LPS / 好中球 … More / 造血幹細胞 / 微小管形成中心（MTOC） / EHNA（阻害剤） / 微小管形成中心(MTOC) / EHNA(阻害剤） / mDia2 / 細胞極性 / 中心体 / 赤芽球 … More Except Principal Investigator 標的治療 / ゲノム編集 / 機能解析 / 遺伝子変異 / 免疫抑制療法 / 体細胞変異 / 骨髄系腫瘍関連遺伝子 / 再発・難治性 / 後天性赤芽球癆 Less

後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発
- Principal Investigator
  
  廣川誠
- Project Period (FY)
  2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Akita University
The mechanism of organelle relocation in human erythroblasts.Principal Investigator
- Principal Investigator
  
  Ubukawa Kumi
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Akita University
The mechanism for determining the position of contraction ring formation in human erythroblast enucleation.Principal Investigator
- Principal Investigator
  
  Ubukawa Kumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Akita University
Human erythroblast enucleation requires dynein depependent cell polarization.Principal Investigator
- Principal Investigator
  
  UBUKAWA Kumi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Hematology
- Research Institution
  Akita University

All 2021 2020 2019 2018 2016 2014

All Journal Article Presentation

[Journal Article] IL-6 Generated from Human Hematopoietic Stem and Progenitor Cells through TLR4 Signaling Promotes Emergency Granulopoiesis by Regulating Transcription Factor Expression2021
- Author(s)
  Sasaki Yumi、Guo Yong-Mei、Goto Tatsufumi、Ubukawa Kumi、Asanuma Ken、Kobayashi Isuzu、Sawada Kenichi、Wakui Hideki、Takahashi Naoto
- Journal Title
  
  The Journal of Immunology
  
  Volume: 207 Issue: 4 Pages: 1078-1086
- DOI
  10.4049/jimmunol.2100168
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08315, KAKENHI-PROJECT-20K17367
[Journal Article] Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts2020
- Author(s)
  Ubukawa Kumi、Goto Tatsufumi、Asanuma Ken、Sasaki Yumi、Guo Yong-Mei、Kobayashi Isuzu、Sawada Kenichi、Wakui Hideki、Takahashi Naoto
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 11806-11806
- DOI
  10.1038/s41598-020-68799-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08315
[Journal Article] Thrombocytopenia Caused by a Tea Beverage of <i>Taxus yunnanensis</i> (Chinese Yew)2019
- Author(s)
  Ubukawa K, Kameoka Y, Guo YM, Nara M, Watanabe A, Fujishima M, Fujishima N, Yoshioka T, Takahashi N.
- Journal Title
  
  Intern. Med.
  
  Volume: 58 Issue: 21 Pages: 3153-3156
- DOI
  10.2169/internalmedicine.2967-19
- NAID
  130007740721
- ISSN
  0918-2918, 1349-7235
- Year and Date
  2019-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08315
[Journal Article] 1.ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts.2019
- Author(s)
  Goto T, Ubukawa K, Kobayashi I, Sugawara K, Asanuma K, Sasaki Y, Guo YM, Takahashi N, Sawada K, Wakui H, Nunomura W.
- Journal Title
  
  Exp Hematol.
  
  Volume: 72
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08315
[Journal Article] The localization of α-synuclein in the process of differentiation of human erythroid cells2018
- Author(s)
  Araki Katsuya、Sugawara Kotomi、Hayakawa Eri H.、Ubukawa Kumi、Kobayashi Isuzu、Wakui Hideki、Takahashi Naoto、Sawada Kenichi、Mochizuki Hideki、Nunomura Wataru
- Journal Title
  
  International Journal of Hematology
  
  Volume: 108 Issue: 2 Pages: 130-138
- DOI
  10.1007/s12185-018-2457-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08315, KAKENHI-PROJECT-18K11135, KAKENHI-PROJECT-16K09716
[Journal Article] 赤血球脱核とその異常2018
- Author(s)
  鵜生川久美
- Journal Title
  
  血液フロンティア
  
  Volume: 28 Pages: 1315-1359
- Data Source
  KAKENHI-PROJECT-18K08315
[Journal Article] Erythroblast enucleation is a dynein-dependent process.2016
- Author(s)
  Kobayashi I, Ubukawa K, Sugawara K, Asanuma K, Guo Y, Yamashita J, Takahashi N, Sawada K, Nunomura W.
- Journal Title
  
  Exp. Hematol.
  
  Volume: 44 Issue: 4 Pages: 247-256
- DOI
  10.1016/j.exphem.2015.12.003
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K09448, KAKENHI-PROJECT-15K19540
[Journal Article] 赤芽球脱核の分子機構と血液疾患2014
- Author(s)
  鵜生川久美、澤田賢一
- Journal Title
  
  血液内科
  
  Volume: 68 Pages: 585-591
- Data Source
  KAKENHI-PROJECT-25860777
[Journal Article] なぜ？どのように？赤芽球の脱核2014
- Author(s)
  鵜生川久美
- Journal Title
  
  血液フロンティア
  
  Volume: 24 Pages: 55-61
- Data Source
  KAKENHI-PROJECT-25860777
[Presentation] Cdc42 regulates terminal differentiation in human erythroblasts.2018
- Author(s)
  Goto T, Ubukawa K, Asanuma K, Kobayashi I, Guo YM, Takahashi N, Wakui H, Nunomura W.
- Organizer
  第80回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08315
[Presentation] ヒト赤芽球の終末分化におけるCdc42の情報伝達経路の解明．2018
- Author(s)
  後藤樹史、鵜生川久美、浅沼研、小林五十鈴、郭永梅、高橋直人、涌井秀樹、布村渉
- Organizer
  第91回日本生化学会学術集会
- Data Source
  KAKENHI-PROJECT-18K08315
[Presentation] 赤芽球におけるα-synuclein の発現と膜結合解析2016
- Author(s)
  菅原琴美, 荒木克哉, 浅沼研, 早川枝李, 鵜生川久美, 小林五十鈴, 山下順助, 高橋直人, 涌井秀樹, 澤田賢一, 望月秀樹, 布村渉
- Organizer
  日本膜学会第38年会
- Place of Presentation
  早稲田大学　西早稲田キャンパス63号館（新宿区）
- Year and Date
  2016-05-10
- Data Source
  KAKENHI-PROJECT-15K19540
[Presentation] Cdc42 regulates enucleation of human erythroblasts.2016
- Author(s)
  Kumi Ubukawa, Tatsufumi Goto, Isuzu Kobayashi, Yong-Mei Guo, Ken Asanuma, Naoto Takahashi, Hideki Wakui & Wataru Nunomura.
- Organizer
  The 2016 ASCB Meeting
- Place of Presentation
  San Francisco (USA).
- Year and Date
  2016-12-03
- Data Source
  KAKENHI-PROJECT-15K19540
[Presentation] ヒドロキシクロロキンによる乳酸脱水素酵素の活性阻害と抗腫瘍効果の解析2016
- Author(s)
  後藤樹史, 菅原琴美, 浅沼研, 小林五十鈴, 鵜生川久美, 郭永梅, 高橋直人, 涌井秀樹, 布村渉
- Organizer
  日本生化学会東北支部会　第82回例会・シンポジウム
- Place of Presentation
  弘前大学医学部・基礎大講堂（弘前市）
- Year and Date
  2016-05-21
- Data Source
  KAKENHI-PROJECT-15K19540
[Presentation] ヒト赤血球系細胞におけるα-synuclein の細胞内局在とリン脂質結合2016
- Author(s)
  菅原琴美, 荒木克哉, 浅沼研, 早川枝李, 鵜生川久美, 小林五十鈴, 山下順助, 高橋直人, 涌井秀樹, 澤田賢一, 望月秀樹, 布村渉
- Organizer
  第36回日本細胞生物学会・日本ケミカルバイオロジー学会第11回年会合同大会
- Place of Presentation
  京都テルサ（京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K19540

1. 高橋直人 (80344753)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 廣川誠 (50241667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 久場敬司 (10451915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 石田文宏 (80311695)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. NUNOMURA Wataru

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ubukawa Kumi 小松 久美

鵜生川久美

UBUKAWA Kumi 鵜生川 久美

Research Projects

Research Products

Co-Researchers

後天性赤芽球癆における体細胞遺伝子変異の機能解明と新規治療基盤の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of organelle relocation in human erythroblasts.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism for determining the position of contraction ring formation in human erythroblast enucleation.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Human erythroblast enucleation requires dynein depependent cell polarization.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] IL-6 Generated from Human Hematopoietic Stem and Progenitor Cells through TLR4 Signaling Promotes Emergency Granulopoiesis by Regulating Transcription Factor Expression2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cdc42 regulates cell polarization and contractile actomyosin rings during terminal differentiation of human erythroblasts2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Thrombocytopenia Caused by a Tea Beverage of <i>Taxus yunnanensis</i> (Chinese Yew)2019

Author(s)

Journal Title

DOI

NAID

ISSN

Year and Date

Language

Data Source

[Journal Article] 1.ATP produced by anaerobic glycolysis is essential for enucleation of human erythroblasts.2019

Author(s)

Journal Title

Data Source

[Journal Article] The localization of α-synuclein in the process of differentiation of human erythroid cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 赤血球脱核とその異常2018

Author(s)

Journal Title

Data Source

[Journal Article] Erythroblast enucleation is a dynein-dependent process.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 赤芽球脱核の分子機構と血液疾患2014

Author(s)

Journal Title

Data Source

[Journal Article] なぜ？どのように？赤芽球の脱核2014

Author(s)

Journal Title

Data Source

[Presentation] Cdc42 regulates terminal differentiation in human erythroblasts.2018

Author(s)

Organizer

Data Source

[Presentation] ヒト赤芽球の終末分化におけるCdc42の情報伝達経路の解明．2018

Ubukawa Kumi 小松久美

UBUKAWA Kumi 鵜生川久美