NAKAZAKI MASAHITO 中崎公仁

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NAKAZAKI Masahito 中崎公仁

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Researcher Number	70722461
Other IDs	https://orcid.org/0000-0003-3155-5116
Affiliation (Current)	2025: 札幌医科大学, 医学部, 特任助教
Affiliation (based on the past Project Information) *help	2025: 札幌医科大学, 医学部, 特任助教 2024: 札幌医科大学, 医学部, その他 2014 – 2020: 札幌医科大学, 医学部, 研究員
Review Section/Research Field	Principal Investigator Basic Section 56020:Orthopedics-related / Neurosurgery Except Principal Investigator Neurosurgery / Basic Section 56010:Neurosurgery-related / Basic Section 56020:Orthopedics-related / Basic Section 59010:Rehabilitation science-related / Rehabilitation science/Welfare engineering / Cerebral neurosurgery
Keywords	Principal Investigator 血管性認知症 / 脳小血管病 / 骨髄間葉系幹細胞 Except Principal Investigator 骨髄間葉系幹細胞 / 骨髄幹細胞 / 脊髄損傷 / 再生医療 / 神経可塑性 / 脳梗塞 / spinal cord injury … More / 間葉系幹細胞 / brain plasticity / 再生医学 / diffusion tensor imaging / 神経再生 / 慢性期 / 可塑性 / リハビリテーション / 幹細胞 / 慢性期脳梗塞 / 拡散MRI / 脊髄介在ニューロン / 神経回路再編 / 神経トレーサー / diffusion tensor / MRI / mesenchymal stem cells / 脳コネクトーム解析 / brain connectivity / 移植 / 治療法 / 分子メカニズム / 浸潤能 / 神経膠腫 / 悪性神経膠腫 / high grade glioma / migration / invasion / prognosis / IL13 receptor alpha 2 / SERPINEA1 / ACTC1 / glioblastoma / glioma / 血管内膜増殖 / 頚動脈損傷 / 再灌流障害 / 脳神経外科学 / 神経再生医療学 / tractography / diffusion MRI / 機能回復 / transplantation / mesenchymal stem cell / 新生児低酸素性虚血性脳症 / 動物モデル / 低酸素性虚血性脳症 Less

骨髄間葉系幹細胞由来の細胞外小胞による神経栄養保護効果増幅機序Principal Investigator
- Principal Investigator
  
  中崎公仁
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
脳梗塞に対する骨髄幹細胞治療による神経回路の再構築の革新的MRIによる統合的解析
- Principal Investigator
  
  長濱宏史
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Sapporo Medical University
脊髄損傷に対する骨髄間葉系幹細胞移植による、脳脊髄の可塑性亢進メカニズムの解析
- Principal Investigator
  
  岡真一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Sapporo Medical University
慢性期脳梗塞に対する骨髄幹細胞治療における至適リハビリ条件の探索
- Principal Investigator
  
  山下達郎
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59010:Rehabilitation science-related
- Research Institution
  Sapporo Medical University
Therapeutic strategies for cerebral infarction and spinal cord injury by activating plasticity throughout the central nervous system
- Principal Investigator
  
  本望修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Sapporo Medical University
Analysis of accelerating plasticity in the brain following intravenous infusion of mesenchymal stem cells in spinal injury
- Principal Investigator
  
  OKA SHINICHI
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  Sapporo Medical University
Intravenous infusion of mesenchymal stem cells enhance plasticity in the brain of rat model of experimental spinal cord injury
- Principal Investigator
  
  Nagahama Hiroshi
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
Analysis of the neural circuits reconstructed by interneurons in mesenchmal stem cell transplantation for spinal cord injury
- Principal Investigator
  
  Hirota Ryosuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56020:Orthopedics-related
- Research Institution
  Sapporo Medical University
analysis of molecular mechanism of invasion in malignant gliomas and development of a novel treatment by inhibition of glioma cell migrations
- Principal Investigator
  
  Wanibuchi Masahiko
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Osaka Medical College
  Sapporo Medical University
Improvement in neural function following intravenous infusion of mesenchymal stem cells in experimental cerebral stroke
- Principal Investigator
  
  Suzuki Junpei
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Functional recovery following intravenous infusion of mesenchymal stem cells via induction of neural plasticity in chronic spinal cord injury
- Principal Investigator
  
  Morita Tomonori
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Development of new therapy with mesenchymal stem cell for reperfusion injury following reperfusion therapy
- Principal Investigator
  
  Honmou Osamu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells
- Principal Investigator
  
  Katsuya Komatsu
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
  Kyoto University
Functional recovery following intravenous infusion of mesenchymal stem cells in experimental spinal cord injury
- Principal Investigator
  
  Sasaki Masanori
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Restoration of cognitive impairment following intravenous infusion of mesenchymal stem cells in a rat model of cerebral small vessel diseasePrincipal Investigator
- Principal Investigator
  
  Nakazaki Masahito
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Analysis of neural plasticity induced by intravenous infusion of mesenchymal stem cells in experimental model of cerebral infarction
- Principal Investigator
  
  Hiroshi Nagahama
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Induced neural plasticity by intravenous infusion of mesenchymal stem cells (MSC) and rehabilitation in ischemic brain
- Principal Investigator
  
  Sasaki Yuichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Rehabilitation science/Welfare engineering
- Research Institution
  Sapporo Medical University
Therapeutic Effects of Intravenous Infusion of MSCs in Hypoxic-Ischemic Encephalopathy Rat
- Principal Investigator
  
  Sakai Takuro
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
INTRAVENOUS INFUSION OF MESENCHYMAL STEM CELLS PROMOTES FUNCTIONAL RECOVERY IN A MODEL OF CHRONIC SPINAL CORD INJURY
- Principal Investigator
  
  Morita Tomonori
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Fundamental analysis of ischemic brain plasticity induced by bone marrow mesenchymal stem cell transplantation
- Principal Investigator
  
  Suzuki Junpei
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Profile analysis of mesenchymal stem cell for cellular therapy
- Principal Investigator
  
  Honmou Osamu
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Functional recovery following intravenous infusion of MSCs via repair of pericytes in rat spinal cord injury
- Principal Investigator
  
  Sasaki Masanori
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  Sapporo Medical University
Characteristic analysis of mesenchymal stem cells for regenerative medicine
- Principal Investigator
  
  RIE Onodera
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Cerebral neurosurgery
- Research Institution
  Sapporo Medical University

All 2019 2018 2017 2016 Other

All Journal Article Presentation

[Journal Article] Intravenous Infusion of Mesenchymal Stem Cells Alters Motor Cortex Gene Expression in a Rat Model of Acute Spinal Cord Injury2019
- Author(s)
  Oshigiri Tsutomu、Sasaki Toru、Sasaki Masanori、Kataoka-Sasaki Yuko、Nakazaki Masahito、Oka Shinichi、Morita Tomonori、Hirota Ryosuke、Yoshimoto Mitsunori、Yamashita Toshihiko、Hashimoto-Torii Kazue、Honmou Osamu
- Journal Title
  
  Journal of Neurotrauma
  
  Volume: 36 Issue: 3 Pages: 411-420
- DOI
  10.1089/neu.2018.5793
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10794, KAKENHI-PROJECT-16K10830, KAKENHI-PROJECT-17K10902
[Journal Article] Intravenous infusion of mesenchymal stem cells improves impaired cognitive function in a cerebral small vessel disease model. Neuroscience.2019
- Author(s)
  3)Nakazaki M, Sasaki M, Kataoka-Sasaki Y, Oka S, Suzuki J, Sasaki Y, Nagahama H, Hashi K, Kocsis JD, Honmou O.
- Journal Title
  
  J Neuroscience.
  
  Volume: 408 Pages: 361-377
- DOI
  10.1016/j.neuroscience.2019.04.018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07569, KAKENHI-PROJECT-19K09461, KAKENHI-PROJECT-17K10901
[Journal Article] 8. Evaluation of the Therapeutic Mechanisms in Regeneration Therapy for Cerebral Infarction Using Pre-clinical Magnetic Resonance Imaging2018
- Author(s)
  Nagahama Hiroshi、Suzuki Junpei、Sasaki Masanori、Nakazaki Masahito、Honmou Osamu
- Journal Title
  
  Japanese Journal of Radiological Technology
  
  Volume: 74 Issue: 7 Pages: 722-725
- DOI
  10.6009/jjrt.2018_JSRT_74.7.722
- NAID
  130007399800
- ISSN
  0369-4305, 1881-4883
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-16K10730
[Journal Article] Preservation of interhemispheric cortical connections through corpus callosum following intravenous infusion of mesenchymal stem cells in a rat model of cerebral infarction2018
- Author(s)
  Nagahama Hiroshi、Nakazaki Masahito、Sasaki Masanori、Kataoka-Sasaki Yuko、Namioka Takahiro、Namioka Ai、Oka Shinichi、Onodera Rie、Suzuki Junpei、Sasaki Yuichi、Kocsis Jeffery D.、Honmou Osamu
- Journal Title
  
  Brain Research
  
  Volume: 1695 Pages: 37-44
- DOI
  10.1016/j.brainres.2018.05.033
- Data Source
  KAKENHI-PROJECT-16K10730
[Journal Article] Intravenous infusion of mesenchymal stem cells for protection against brainstem infarction in a persistent basilar artery occlusion model in the adult rat2018
- Author(s)
  Namioka Ai、Namioka Takahiro、Sasaki Masanori、Kataoka-Sasaki Yuko、Oka Shinichi、Nakazaki Masahito、Onodera Rie、Suzuki Junpei、Sasaki Yuichi、Nagahama Hiroshi、Kocsis Jeffery D.、Honmou Osamu
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: Oct1 Issue: 4 Pages: 1-9
- DOI
  10.3171/2018.4.jns173121
- Data Source
  KAKENHI-PROJECT-16K10730
[Journal Article] Intravenous infusion of mesenchymal stem cells promotes functional recovery in a rat model of chronic cerebral infarction2018
- Author(s)
  Namioka Takahiro、Namioka Ai、Sasaki Masanori、Kataoka-Sasaki Yuko、Oka Shinichi、Nakazaki Masahito、Onodera Rie、Suzuki Junpei、Sasaki Yuichi、Nagahama Hiroshi、Kocsis Jeffery D.、Honmou Osamu
- Journal Title
  
  Journal of Neurosurgery
  
  Volume: Oct1 Issue: 4 Pages: 1-8
- DOI
  10.3171/2018.5.jns18140
- Data Source
  KAKENHI-PROJECT-16K10730
[Journal Article] Functional recovery after the systemic administration of mesenchymal stem cells in a rat model of neonatal hypoxia-ischemia2018
- Author(s)
  Sakai Takuro、Sasaki Masanori、Kataoka-Sasaki Yuko、Oka Shinichi、Nakazaki Masahito、Fukumura Shinobu、Kobayashi Masaki、Tsutsumi Hiroyuki、Kocsis Jeffery D.、Honmou Osamu
- Journal Title
  
  Journal of Neurosurgery: Pediatrics
  
  Volume: 22 Issue: 5 Pages: 513-522
- DOI
  10.3171/2018.5.peds1845
- Data Source
  KAKENHI-PROJECT-16K10730
[Journal Article] Elevated brain derived neurotrophic factor (BDNF) levels in plasma but not serum reflect in vivo functional viability of infused mesenchymal stem cells after middle cerebral artery occlusion in rat.2017
- Author(s)
  Nakamura H, Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Namioka T, Namioka A, Onodera R, Suzuki J, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O.
- Journal Title
  
  J Neurosurg Sci.
  
  Volume: 印刷中 Issue: 4 Pages: 926-926
- DOI
  10.3171/2016.8.jns16240
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K10730
[Journal Article] Elevated brain derived neurotrophic factor (BDNF) levels in plasma but not serum reflect in vivo functional viability of infused mesenchymal stem cells after middle cerebral artery occlusion in rat.2017
- Author(s)
  Nakamura H, Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Oka S, Nakazaki M, Namioka T, Namioka A, Onodera R, Suzuki J, Nagahama H, Mikami T, Wanibuchi M, Kocsis JD, Honmou O.
- Journal Title
  
  Journal of Neurosurgical Sciences
  
  Volume: Feb 8 Issue: 1
- DOI
  10.23736/s0390-5616.17.03989-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26350618, KAKENHI-PROJECT-16K10730
[Journal Article] Synergic effects of rehabilitation and intravenous infusion of mesenchymal stem cells after stroke in rats.2016
- Author(s)
  Sasaki Y, Sasaki M, Kataoka-Sasaki Y, Nakazaki M, Nagahama H, Suzuki J, Tateyama D, Oka S, Namioka T, Namioka A, Onodera R, Mikami T, Wanibuchi M, Kakizawa M, Ishiai S, Kocsis JD, Honmou O
- Journal Title
  
  Physical Therapy
  
  Volume: 96(11) Issue: 11 Pages: 1791-1798
- DOI
  10.2522/ptj.20150504
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23500596, KAKENHI-PROJECT-26350618
[Journal Article] INTRAVENOUS INFUSION OF MESENCHYMAL STEM CELLS PROMOTES FUNCTIONAL RECOVERY IN A MODEL OF CHRONIC SPINAL CORD INJURY2016
- Author(s)
  Tomonori Morita, Masanori Sasaki, Yukon Kataoka-Sasaki, Masahito Nakazaki, Hiroshi Nagahama, Shinichi Oka, Tsutomu Oshigiri, Tsuneo Takebayashi, Toshihiko Yamashita, Jeffery D. Kocsis, Osamu Honmou
- Journal Title
  
  Neuroscience
  
  Volume: 335 Pages: 221-231
- DOI
  10.1016/j.neuroscience.2016.08.037
- NAID
  40021725590
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462213, KAKENHI-PROJECT-16K10794
[Presentation] INTRAVENOUS INFUSION OF MESENCHYMAL STEM CELLS PROMOTES FUNCTIONAL RECOVERY IN A MODEL OF CHRONIC SPINAL CORD INJURY2017
- Author(s)
  Tomonori Morita, Masanori Sasaki, Yukon Kataoka-Sasaki, Masahito Nakazaki, Hiroshi Nagahama, Shinichi Oka, Tsutomu Oshigiri, Tsuneo Takebayashi, Toshihiko Yamashita, Jeffery D. Kocsis, Osamu Honmou
- Organizer
  Orthopaedic Research Society 2017 Annual Meeting
- Place of Presentation
  San Diego
- Year and Date
  2017-03-19
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462213
[Presentation] ラット慢性期脊髄損傷モデルに対する骨髄間葉系幹細胞の経静脈的投与による機能回復の検討2016
- Author(s)
  森田智慶, 佐々木祐典, 佐々木優子, 中崎公仁, 長濱宏史, 岡真一, 押切勉, 竹林庸雄, 山下敏彦, 本望修
- Organizer
  第131回北海道整形災害外科学会
- Place of Presentation
  函館
- Year and Date
  2016-06-04
- Data Source
  KAKENHI-PROJECT-26462213
[Presentation] 脊髄損傷患者に対する自己培養骨髄間葉系幹細胞の静脈内投与
- Author(s)
  本望修　佐々木祐典　岡真一　中崎公仁　森田智慶　竹林庸雄　山下敏彦
- Organizer
  第48回日本脊髄障害医学会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-25462227

1. SASAKI Masanori (20538136)

# of Collaborated Projects: 21 results

# of Collaborated Products: 12 results
2. HONMOU Osamu (90285007)

# of Collaborated Projects: 17 results

# of Collaborated Products: 9 results
3. WANIBUCHI Masahiko (30343388)

# of Collaborated Projects: 12 results

# of Collaborated Products: 1 results
4. MIKAMI Takeshi (30372816)

# of Collaborated Projects: 9 results

# of Collaborated Products: 1 results
5. Namioka Ai (60748995)

# of Collaborated Projects: 9 results

# of Collaborated Products: 5 results
6. Namioka Takahiro (70748996)

# of Collaborated Projects: 9 results

# of Collaborated Products: 5 results
7. SUZUKI Junpei (00572596)

# of Collaborated Projects: 8 results

# of Collaborated Products: 0 results
8. Hiroshi Nagahama (20725676)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
9. SASAKI Yuichi (00570136)

# of Collaborated Projects: 6 results

# of Collaborated Products: 2 results
10. MORITA Tomonori (60723343)

# of Collaborated Projects: 6 results

# of Collaborated Products: 4 results
11. OKA SHINICHI (70789453)

# of Collaborated Projects: 6 results

# of Collaborated Products: 1 results
12. 佐々木優子 (80631142)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
13. SAKAI Takurou (80639229)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
14. KOBAYASHI Masaki (70592715)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
15. 押切勉 (70754612)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
16. RIE Onodera (60393328)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
17. Hirota Ryosuke (10815434)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
18. 山下敏彦 (70244366)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
19. 鵜飼亮 (30896113)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
20. Katsuya Komatsu (60749498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
21. 三國信啓 (60314217)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
22. 横山貴裕 (60896116)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
23. 山下達郎 (60815439)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
24. 福村忍 (30718341)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 竹林庸雄 (30347166)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
26. 飯星智史 (60457710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 鳥越俊彦 (20301400)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 寺島嘉紀 (20438005)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 福士龍之介 (00894065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. 小原尚 (20919732)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. 小林萬里 (50971074)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. ISHIAI Sumio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

NAKAZAKI MASAHITO 中崎 公仁

NAKAZAKI Masahito 中崎 公仁

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Restoration of cognitive impairment following intravenous infusion of mesenchymal stem cells in a rat model of cerebral small vessel diseasePrincipal Investigator

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NAKAZAKI MASAHITO 中崎公仁

NAKAZAKI Masahito 中崎公仁