Kawano Kenichi 河野健一

… Alternative Names

Kenichi Kawano 河野健一

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Researcher Number	70732874
Other IDs	https://orcid.org/0000-0003-1927-2922
Affiliation (Current)	2025: 京都大学, 薬学研究科, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 京都大学, 薬学研究科, 助教 2016 – 2019: 京都大学, 化学研究所, 助教 2015: 京都大学, 学内共同利用施設等, 研究員 2015: 京都大学, 物質-細胞統合システム拠点, 研究員 2014: 京都大学, ウイルス研究所, 助教
Review Section/Research Field	Principal Investigator Basic Section 47030:Pharmaceutical hygiene and biochemistry-related / Basic Section 43040:Biophysics-related / Physical pharmacy Except Principal Investigator Medium-sized Section 47:Pharmaceutical sciences and related fields / Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related / Drug development chemistry / Physical pharmacy
Keywords	Principal Investigator 細胞外小胞 / 曲率認識ペプチド / 1細胞解析 / オートインデューサー / マイクロ流路デバイス / 蛍光イメージング / 免疫細胞 / 超遠心分離法 / 腸内細菌 / 免疫活性 … More / アジュバント / 脂質パッキング / 直接膜透過 / 膜透過性ペプチド / 錯体化学 / 境界領域 / 細胞膜 / 錯体脂質 / 人工脂質ラフト / 二量体 / アマンタジン耐性 / A型インフルエンザウイルス / 溶液NMR / S31N変異体 / M2プロトンチャネル / 可溶化剤 … More Except Principal Investigator 膜タンパク質 / 可溶化剤 / 膜タンパク質可溶化 / アミロイドβ / アルツハイマー病 / 薬物送達 / 細胞 / 蛋白質 / 薬学 / エンドソーム膜不安定化ペプチド / バイオ高分子医薬品 / バイオ医薬品 / 膜傷害性ペプチド / クモ毒 / マクロピノサイトーシス / エンドサイトーシス / 抗体 / 細胞内送達 / 蛍光イメージング Less

Exploration for functional factors governing the diversity of extracellular vesicles: Single-cell analysisPrincipal Investigator
- Principal Investigator
  
  河野健一
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kyoto University
新規リン脂質誘導体可溶化剤を用いた革新的膜タンパク質研究プラットホームの構築
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 47:Pharmaceutical sciences and related fields
- Research Institution
  Kyoto University
Exploration of adjuvant-active substances derived from extracellular membrane vesiclesPrincipal Investigator
- Principal Investigator
  
  Kenichi Kawano
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kyoto University
In-cell分光法によるアミロイドβ産生制御機構・構造変化の解明と創薬
- Principal Investigator
  
  松崎勝巳
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47020:Pharmaceutical analytical chemistry and physicochemistry-related
- Research Institution
  Kyoto University
Elucidation of the mechanism underlying the influx point of cell-penetrating peptides using artificial lipid domainsPrincipal Investigator
- Principal Investigator
  
  Kawano Kenichi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43040:Biophysics-related
- Research Institution
  Kyoto University
Development of a novel fluorescent labeling method for detecting heterooligomers of membrane proteins on living cells
- Principal Investigator
  
  Katsumi Matsuzaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University
New strategy for intracellular delivery of biomacropharmaceuticals
- Principal Investigator
  
  Futaki Shiroh
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Drug development chemistry
- Research Institution
  Kyoto University
Structural analysis of Am-resistant M2-S31N mutant using a novel detergent and solution NMRPrincipal Investigator
- Principal Investigator
  
  Kawano Kenichi
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyoto University

All 2024 2023 2022 2021 2019

All Journal Article Presentation

[Journal Article] Extracellular-Vesicle Catch-and-Release Isolation System Using a Net-Charge Invertible Curvature-Sensing Peptide2024
- Author(s)
  Kawano Kenichi、Kuzuma Yuki、Yoshio Koichi、Hosokawa Kenta、Oosugi Yuuto、Fujiwara Takahiro、Yokoyama Fumiaki、Matsuzaki Katsumi
- Journal Title
  
  Analytical Chemistry
  
  Volume: 96 Issue: 9 Pages: 3754-3762
- DOI
  10.1021/acs.analchem.3c03756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K14516, KAKENHI-PROJECT-23KJ0327, KAKENHI-PROJECT-21K15254
[Journal Article] Loosening of Lipid Packing by Cell‐Surface Recruitment of Amphiphilic Peptides by Coiled‐Coil Tethering2019
- Author(s)
  Sakai Takayuki、Kawano Kenichi、Iino Masatomo、Takeuchi Toshihide、Imanishi Miki、Futaki Shiroh
- Journal Title
  
  ChemBioChem
  
  Volume: 20 Issue: 16 Pages: 2151-2159
- DOI
  10.1002/cbic.201900347
- Peer Reviewed
- Data Source
  KAKENHI-PUBLICLY-18H04547, KAKENHI-PROJECT-18K14664
[Presentation] 曲率認識ペプチドを用いた新規手法で単離した細胞外小胞の機能性評価2024
- Author(s)
  河野健一, 葛馬佑樹, 吉尾航一, 細川健太, 大杉悠斗, 藤原敬宏, 横山文秋, 松﨑勝巳
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-21K15254
[Presentation] リン脂質誘導体カクテルによる膜タンパク質の小サイズでの安定な可溶化2024
- Author(s)
  松崎勝巳; 高木麻衣; 秦綾美; 長谷綾菜; 横山あずさ; 林田幸一; 星遥華; 山崎大資; 大山侃志; 河野健一; 黒田悠介; 山岡庸介; 星野大; 矢野義明; 高須清誠日本薬学会第144年会
- Organizer
  日本薬学会第144年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K18184
[Presentation] 新規リン脂質誘導体による可溶化GPCRのリガンド結合能評価2024
- Author(s)
  星遥華; 河野健一; 藤原敬宏; 黒田悠介; 山岡庸介; 高須清誠; 松崎勝巳
- Organizer
  日本薬学会第144年会
- Data Source
  KAKENHI-PROJECT-23K18184
[Presentation] 神経細胞膜上における Aβ40 と 42 共存下での線維形成機構2023
- Author(s)
  川口真由; 河野健一; 松崎勝巳
- Organizer
  第44回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21355
[Presentation] Extracellular-vesicle catch-and-release isolation system using a ph-dependent EV-binding curvature-sensing peptide2023
- Author(s)
  Kenichi Kawano, Yuki Kuzuma, Takahiro Fujiwara, Fumiaki Yokoyama, Katsumi Matsuzaki
- Organizer
  第60回ペプチド討論会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15254
[Presentation] 電荷反転型曲率認識ペプチドを用いた細胞外小胞の簡便な回収法の開発2023
- Author(s)
  河野健一, 葛馬佑樹, 藤原敬宏, 横山文秋, 松﨑勝巳
- Organizer
  「日本膜学会第45年会」・「膜シンポジウム2023」合同大会
- Data Source
  KAKENHI-PROJECT-21K15254
[Presentation] 細胞外小胞の単離に向けた新規 pH 応答性曲率認識ペプチドの設計2023
- Author(s)
  葛馬佑樹、河野健一、松崎勝巳
- Organizer
  日本薬学会第143年会
- Data Source
  KAKENHI-PROJECT-21K15254
[Presentation] 細胞外小胞の高感度検出を基軸とした曲率認識ペプチドの創製研究2022
- Author(s)
  河野健一、葛馬佑樹、横山文秋、釜阪紘平、小川拓哉、川本純、栗原達夫、松﨑勝巳
- Organizer
  第16回バイオ関連化学シンポジウム
- Data Source
  KAKENHI-PROJECT-21K15254
[Presentation] STRUCTURAL FACTORS GOVERNING VESICLE DETECTION OF CURVATURE-SENSING PEPTIDES2022
- Author(s)
  Kenichi Kawano, Fumiaki Yokoyama, Kouhei Kamasaka, Jun Kawamoto, Takuya Ogawa, Tatsuo Kurihara, and Katsumi Matsuzaki
- Organizer
  The 59th Japanese Peptide Symposium
- Data Source
  KAKENHI-PROJECT-21K15254
[Presentation] 生細胞膜中で形成されるアミロイドβタンパク質の構造解析2021
- Author(s)
  角友登、河野健一、矢野義明、星野大、松崎勝巳
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-23K21355
[Presentation] 人工ドメイン形成による膜物性および細胞形態の変化2019
- Author(s)
  河野健一, 高橋康史, 大谷亮, 木下祥尚
- Organizer
  膜シンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K14664
[Presentation] 錯体脂質を用いた生細胞膜上における人工ドメイン構築2019
- Author(s)
  河野健一, 高橋康史, 大谷亮, 木下祥尚
- Organizer
  第13回バイオ関連化学シンポジウム2019
- Data Source
  KAKENHI-PROJECT-18K14664
[Presentation] Induction and reversible control of phase separation on living cell membranes2019
- Author(s)
  Kenichi Kawano, Yasufumi Takahashi, Ryo Ohtani, Masanao Kinoshita, Shiroh Futaki
- Organizer
  第57回日本生物物理化学学会例会
- Data Source
  KAKENHI-PROJECT-18K14664
[Presentation] 生細胞膜上における相分離の誘発と可逆的制御2019
- Author(s)
  河野健一, 高橋康史, 大谷亮, 木下祥尚, 二木史朗
- Organizer
  第17回フィジカルファーマフォーラム
- Data Source
  KAKENHI-PROJECT-18K14664

1. Katsumi Matsuzaki (00201773)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Futaki Shiroh (50199402)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. TAKEUCHI Toshihide (70600120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 星野忠次 (90257220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 星野大 (70304053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
6. 松崎勝己

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 横山文秋

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 二木史郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kawano Kenichi 河野 健一

Kenichi Kawano 河野 健一

Research Projects

Research Products

Co-Researchers

Exploration for functional factors governing the diversity of extracellular vesicles: Single-cell analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規リン脂質誘導体可溶化剤を用いた革新的膜タンパク質研究プラットホームの構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of adjuvant-active substances derived from extracellular membrane vesiclesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

In-cell分光法によるアミロイドβ産生制御機構・構造変化の解明と創薬

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism underlying the influx point of cell-penetrating peptides using artificial lipid domainsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a novel fluorescent labeling method for detecting heterooligomers of membrane proteins on living cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

New strategy for intracellular delivery of biomacropharmaceuticals

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Structural analysis of Am-resistant M2-S31N mutant using a novel detergent and solution NMRPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Extracellular-Vesicle Catch-and-Release Isolation System Using a Net-Charge Invertible Curvature-Sensing Peptide2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Loosening of Lipid Packing by Cell‐Surface Recruitment of Amphiphilic Peptides by Coiled‐Coil Tethering2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] 曲率認識ペプチドを用いた新規手法で単離した細胞外小胞の機能性評価2024

Author(s)

Organizer

Data Source

[Presentation] リン脂質誘導体カクテルによる膜タンパク質の小サイズでの安定な可溶化2024

Author(s)

Organizer

Data Source

[Presentation] 新規リン脂質誘導体による可溶化GPCRのリガンド結合能評価2024

Author(s)

Organizer

Data Source

[Presentation] 神経細胞膜上における Aβ40 と 42 共存下での線維形成機構2023

Author(s)

Organizer

Data Source

[Presentation] Extracellular-vesicle catch-and-release isolation system using a ph-dependent EV-binding curvature-sensing peptide2023

Kawano Kenichi 河野健一

Kenichi Kawano 河野健一