Tsubouchi Tomomi 坪内知美

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TSUBOUCHI Tomomi 坪内知美

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Researcher Number	70754505
Other IDs
Affiliation (Current)	2025: 静岡大学, 農学部, 准教授 2025: 基礎生物学研究所, 幹細胞生物学研究室, 准教授(兼任)
Affiliation (based on the past Project Information) *help	2025: 基礎生物学研究所, 幹細胞生物学研究室, 准教授 2016 – 2022: 基礎生物学研究所, 幹細胞生物学研究室, 准教授
Review Section/Research Field	Principal Investigator Basic Section 43010:Molecular biology-related / Developmental biology / Biological Sciences Except Principal Investigator Biological Sciences / Molecular biology
Keywords	Principal Investigator ゲノム恒常性 / 幹細胞 / 多能性幹細胞 / ｄNTP産生 / DNA 複製 / dNTP産生 / ES細胞 / dNTP / DNA複製 / 胚性幹細胞 … More / DNA損傷 / 多能性誘導 / DNA損傷応答 / ゲノム不安定化 / 多能性獲得 … More Except Principal Investigator 1細胞解析 / 多能性 / 幹細胞 / ES細胞 / クロマチン / ゲノム恒常性 / DNA損傷 / 多能性幹細胞 / 遺伝学 / 出芽酵母 / 染色体構造 / 細胞周期 / 染色体 / シナプトネマ複合体 / 相同組換え / 減数分裂 Less

多能性幹細胞を支えるDNA複製制御機構の理解Principal Investigator
- Principal Investigator
  
  坪内知美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43010:Molecular biology-related
- Research Institution
  National Institute for Basic Biology
Mechanisms of maintenance and regeneration of pluripotent stem cells
- Principal Investigator
  
  Umeda Masaaki
- Project Period (FY)
  2017 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nara Institute of Science and Technology
多能性誘導過程におけるゲノム恒常性Principal Investigator
- Principal Investigator
  
  坪内知美
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  National Institute for Basic Biology
Genome Maintenance Mechanisms in Pluropotent Stem CellsPrincipal Investigator
- Principal Investigator
  
  Tsubouchi Tomomi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  National Institute for Basic Biology
Understanding the mechanisms for ensuring timely destruction of the synaptonemal complex during meiosis
- Principal Investigator
  
  TSUBOUCHI Hideo
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Molecular biology
- Research Institution
  Tokyo Institute of Technology
  National Institute for Basic Biology

All 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Polo is not solo in meiosis2018
- Author(s)
  Argunhan Bilge、Tsubouchi Tomomi、Tsubouchi Hideo
- Journal Title
  
  Cell Cycle
  
  Volume: (17) 3 Issue: 3 Pages: 1-2
- DOI
  10.1080/15384101.2017.1411435
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07422
[Journal Article] Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis.2017
- Author(s)
  Argunhan B, Leung WK, Afshar N, Terentyev Y, Subramanian VV, Murayama Y, Hochwagen A, Iwasaki H, Tsubouchi T, Tsubouchi H.
- Journal Title
  
  EMBO J
  
  Volume: 36 Issue: 17 Pages: 2488-2509
- DOI
  10.15252/embj.201695895
- NAID
  120007117670
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-INTERNATIONAL-15K21761, KAKENHI-PUBLICLY-16H01404, KAKENHI-PROJECT-16H06160, KAKENHI-PROJECT-16H07422, KAKENHI-PLANNED-15H05974
[Journal Article] Exiting prophase I: no clear boundary2017
- Author(s)
  Tsubouchi Hideo、Argunhan Bilge、Tsubouchi Tomomi
- Journal Title
  
  Current Genetics
  
  Volume: 64 Issue: 2 Pages: 423-427
- DOI
  10.1007/s00294-017-0771-y
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H07422
[Presentation] Regulation of DNA replication in mammalian pluripotent stem cells2020
- Author(s)
  Yasunao Kamikawa、Akino Matsumoto、Tomomi Tsubouchi
- Organizer
  JSDB Online Meeting
- Data Source
  KAKENHI-PLANNED-17H06477
[Presentation] Regulation of DNA replication in mammalian pluripotent stem cells2019
- Author(s)
  Tomomi Tsubouchi
- Organizer
  International Symposium for Female Researchers in Chromatin Biology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 哺乳類多能性幹細胞におけるDNA複製制御2019
- Author(s)
  坪内知美
- Organizer
  第37回染色体ワークショップ/ 第18回核ダイナミクス研究会
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 哺乳類多能性幹細胞におけるDNA複製ストレスと複製制御2019
- Author(s)
  上川泰直、長沼麻衣、坪内知美
- Organizer
  第42回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] A unique regulation of dNTP levels in mammalian pluripotent stem cells2019
- Author(s)
  Yasunao Kamikawa, Akino Matsumoto and Tomomi Tsubouchi
- Organizer
  Cold Spring Harbor Laboratory Meeting: Eukaryotic DNA Replicatin & Genome Maintenance
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 多能性幹細胞におけるdNTP産生制御とゲノム恒常性2019
- Author(s)
  上川泰直、松本陽乃、坪内知美
- Organizer
  第25回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 多能性幹細胞におけるDNA複製完了のメカニズム2018
- Author(s)
  上川泰直　坪内知美
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 多能性幹細胞におけるDNA複製ストレス応答2018
- Author(s)
  上川泰直、坪内知美
- Organizer
  日本遺伝学会第90回大会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06477
[Presentation] 多能性幹細胞におけるDNA複製ストレス応答2018
- Author(s)
  上川泰直　坪内知美
- Organizer
  第90回日本遺伝学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 多能性細胞におけるゲノム恒常性維持機構（仮題）2018
- Author(s)
  坪内知美
- Organizer
  日本分子生物学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 多能性幹細胞におけるDNA複製完了のメカニズム2018
- Author(s)
  上川泰直、坪内知美
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06477
[Presentation] Unique regulation of dNTP production in mammalian pluripotent stem cells2018
- Author(s)
  上川泰直　坪内知美
- Organizer
  EMBO workshop on DNA Replication, Chromosome Segregation and Fate Decisions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] Genome maintenance mechanisms in mammalian pluripotent stem cells2018
- Author(s)
  上川泰直、坪内知美
- Organizer
  第59回日本植物生理学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06477
[Presentation] 多能性細胞の複製ストレス応答機構（仮題）2018
- Author(s)
  上川泰直　坪内知美
- Organizer
  日本遺伝学会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 複製フォーク動態を介した多能性幹細胞におけるゲノム安定性維持機構2018
- Author(s)
  上川泰直、坪内知美
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PLANNED-17H06477
[Presentation] Unique regulation of dNTP production in mammalian pluripotent stem cells2018
- Author(s)
  上川泰直、坪内知美
- Organizer
  EMBO Workshop on DNA Replication, Chromosome Segregation and Fate Decisions
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-17H06477
[Presentation] 多能性とゲノム恒常性（仮題）2018
- Author(s)
  上川泰直　坪内知美
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-16H01412
[Presentation] 複製フォーク動態を介した多能性幹細胞におけるゲノム安定性維持機構2018
- Author(s)
  上川泰直　坪内知美
- Organizer
  第41回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] Live-imaging study of cells undergoing reprogramming towards pluripotency2017
- Author(s)
  熊崎泰成　坪内知美
- Organizer
  2017年度生命科学系合同年次大会（第４０回日本分子生物学会年会）
- Data Source
  KAKENHI-PUBLICLY-16H01412
[Presentation] DNA replication and genome stability in pluripotent stem cells2017
- Author(s)
  坪内知美
- Organizer
  2017年度生命科学系合同年次大会（第40回日本分子生物学会年会）
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 減数分裂期特異的に形成される高次染色体構造を解消するメカニズム2017
- Author(s)
  坪内英生
- Organizer
  第24回DNA複製・組換え・修復ワークショップ
- Data Source
  KAKENHI-PROJECT-16H07422
[Presentation] Genome maintenance mechanisms in mammalian pluripotent stem cells2017
- Author(s)
  坪内知美
- Organizer
  第５９回日本植物生理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-16K07382
[Presentation] 多能性細胞におけるDNA複製とゲノム恒常性2017
- Author(s)
  上川泰直、坪内知美
- Organizer
  第40回日本分子生物学会年会
- Data Source
  KAKENHI-PLANNED-17H06477

1. TSUBOUCHI Hideo (20283822)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
2. ARGUNHAN Bilge (30792759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
3. Umeda Masaaki (80221810)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 蓑田亜希子 (40721569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 岩崎博史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Tsubouchi Tomomi 坪内 知美

TSUBOUCHI Tomomi 坪内 知美

Research Projects

Research Products

Co-Researchers

多能性幹細胞を支えるDNA複製制御機構の理解Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of maintenance and regeneration of pluripotent stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

多能性誘導過程におけるゲノム恒常性Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Genome Maintenance Mechanisms in Pluropotent Stem CellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Understanding the mechanisms for ensuring timely destruction of the synaptonemal complex during meiosis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Polo is not solo in meiosis2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Fundamental cell cycle kinases collaborate to ensure timely destruction of the synaptonemal complex during meiosis.2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Exiting prophase I: no clear boundary2017

Author(s)

Journal Title

DOI

Data Source

[Presentation] Regulation of DNA replication in mammalian pluripotent stem cells2020

Author(s)

Organizer

Data Source

[Presentation] Regulation of DNA replication in mammalian pluripotent stem cells2019

Author(s)

Organizer

Data Source

[Presentation] 哺乳類多能性幹細胞におけるDNA複製制御2019

Author(s)

Organizer

Data Source

[Presentation] 哺乳類多能性幹細胞におけるDNA複製ストレスと複製制御2019

Author(s)

Organizer

Data Source

[Presentation] A unique regulation of dNTP levels in mammalian pluripotent stem cells2019

Author(s)

Organizer

Data Source

[Presentation] 多能性幹細胞におけるdNTP産生制御とゲノム恒常性2019

Author(s)

Organizer

Data Source

[Presentation] 多能性幹細胞におけるDNA複製完了のメカニズム2018

Author(s)

Organizer

Data Source

[Presentation] 多能性幹細胞におけるDNA複製ストレス応答2018

Tsubouchi Tomomi 坪内知美

TSUBOUCHI Tomomi 坪内知美