Miyawaki Shingo 宮脇慎吾

… Alternative Names

MIYAWAKI Shingo 宮脇慎吾

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Researcher Number	70756759
Other IDs
Affiliation (Current)	2025: 岐阜大学, 応用生物科学部, 准教授
Affiliation (based on the past Project Information) *help	2022 – 2024: 岐阜大学, 応用生物科学部, 准教授 2020 – 2021: 岐阜大学, 応用生物科学部, 助教 2019: 大阪大学, 生命機能研究科, 特任助教(常勤) 2018: 徳島大学, 先端酵素学研究所(次世代), 特任助教 2017: 徳島大学, 先端酵素学研究所(次世代), 助教
Review Section/Research Field	Principal Investigator Basic Section 42020:Veterinary medical science-related / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields / Basic Section 48020:Physiology-related / Obstetrics and gynecology Except Principal Investigator Medium-sized Section 42:Veterinary medical science, animal science, and related fields / Basic Section 42020:Veterinary medical science-related / Medium-sized Section 58:Society medicine, nursing, and related fields / Basic Section 58020:Hygiene and public health-related: including laboratory approach / Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
Keywords	Principal Investigator ゲノム編集 / マウス / 遺伝性疾患 / 犬 / Cryptic exon / 生殖腺体細胞 / Sry / 代謝 / エピゲノム / 性決定 … More / 獣医学 / 遺伝子治療 / トランスクリプト / 長鎖RNAシーケンス / long read / cryptic exon / 遺伝子 / 環境 … More Except Principal Investigator 免疫 / マウス / ゲノム編集 / 生体防御 / 血液凝固 / 接触活性化因子 / 犬 / 感染感受性 / 宿主域 / コウモリ / 人獣共通感染症 / 野生動物 / ストレス / 下行性疼痛制御経路 / 下行性疼痛抑制経路 / 脊髄 / 大腸運動 / 排便 / 消化管 / 自然免疫 / トキソプラズマ / ウイルス / 転写誤調節 / 遺伝子編集 / 低温耐性 / 選択的スプライシング / 転写後調節 / 低温ショックタンパク質 / 低体温 / 冬眠 / イヌ / 修飾遺伝子 / Autopsy imaging / 遺伝性疾患 / 消化管腫瘍 / 家族性大腸腺腫症 / ジャックラッセルテリア / 遺伝性消化管ポリポーシス / タンパク質分解 / 性決定因子 / 相互作用因子 / ゲノム進化 / 性決定遺伝子 / Sry / 性決定 Less

犬の遺伝性疾患“再現マウス”を活用したゲノム編集治療法の開発Principal Investigator
- Principal Investigator
  
  宮脇慎吾
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Comprehensive understanding of the antiviral innate immune response elicited by latently infected protozoan parasites
- Principal Investigator
  
  正谷達謄
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58020:Hygiene and public health-related: including laboratory approach
- Research Institution
  Gifu University
脳と大腸を機能連関させる神経回路のリモデリングとその排便異常への関与
- Principal Investigator
  
  志水泰武
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Gifu University
致死性病原体の潜伏を可能にする野生動物の分子免疫機構
- Principal Investigator
  
  高島康弘
- Project Period (FY)
  2023 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 58:Society medicine, nursing, and related fields
- Research Institution
  Gifu University
A new interpretation of contact activation system: A host defense mechanism for hemostasis and infection control
- Principal Investigator
  
  鬼頭克也
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
犬の新たな遺伝性疾患である「消化管腫瘍性ポリポーシス」の重症化機構の解明
- Principal Investigator
  
  平田暁大
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
Mechanisms of low temperature tolerance common to mammals as a basis for induction of artificial hibernation.
- Principal Investigator
  
  Shimizu Yasutake
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 42:Veterinary medical science, animal science, and related fields
- Research Institution
  Gifu University
Revision of the mechanism of action of the mammalian sex-determining gene Sry and its genome evolutionary process
- Principal Investigator
  
  Tachibana Makoto
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Osaka University
Identification of Cryptic exon by long RNA sequencingPrincipal Investigator
- Principal Investigator
  
  Miyawaki Shingo
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 43:Biology at molecular to cellular levels, and related fields
- Research Institution
  Gifu University
elucidate the causes of genetic diseases in dogs using genome-edited micePrincipal Investigator
- Principal Investigator
  
  宮脇慎吾
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42020:Veterinary medical science-related
- Research Institution
  Gifu University
EFFECT OF MATERNAL DIET AND NUTRITIONAL STATUS ON MAMMALIAN SEX DETERMINATIONPrincipal Investigator
- Principal Investigator
  
  Miyawaki Shingo
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Gifu University
  Osaka University
The influence of maternal nutrition on sex determinationPrincipal Investigator
- Principal Investigator
  
  MIYAWAKI Shingo
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Obstetrics and gynecology
- Research Institution
  The University of Tokushima

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Book

[Book] The Evolutionary Aspects of the Mammalian Sex-Determining Gene SRY.2023
- Author(s)
  Shingo Miyawaki and Makoto Tachibana
- Total Pages
  17
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-21H04769
[Book] The Evolutionary Aspects of the Mammalian Sex-Determining Gene SRY2023
- Author(s)
  Shingo Miyawaki and Makoto Tachibana
- Total Pages
  17
- Publisher
  Springer Nature
- Data Source
  KAKENHI-PROJECT-21H04769
[Journal Article] The Evolutionary Aspects of the Mammalian Sex-Determining Gene SRY2022
- Author(s)
  Miyawaki Shingo、Tachibana Makoto
- Journal Title
  
  Spectrum of Sex
  
  Volume: 1 Pages: 69-84
- DOI
  10.1007/978-981-19-5359-0_5
- ISBN
  9789811953583, 9789811953590
- Data Source
  KAKENHI-PROJECT-21K19213
[Journal Article] マウスの性決定遺伝子Sryにおける「隠れエキソン」と，それがコードする真の性決定因子SRY-Tの発見2021
- Author(s)
  宮脇慎吾、立花誠
- Journal Title
  
  実験医学
  
  Volume: 39(4) Pages: 571-574
- Data Source
  KAKENHI-PROJECT-19K16490
[Journal Article] 性決定遺伝子の全貌-マウスSryにおける“隠れエキソン”の発見-2021
- Author(s)
  宮脇慎吾、立花誠
- Journal Title
  
  医学のあゆみ
  
  Volume: 278 Pages: 1132-1133
- Data Source
  KAKENHI-PROJECT-21H04769
[Journal Article] The mouse Sry locus harbors a cryptic exon that is essential for male sex determination2020
- Author(s)
  Miyawaki Shingo、Kuroki Shunsuke、Maeda Ryo、Okashita Naoki、Koopman Peter、Tachibana Makoto
- Journal Title
  
  Science
  
  Volume: 370 Issue: 6512 Pages: 121-124
- DOI
  10.1126/science.abb6430
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05364, KAKENHI-PROJECT-18H02419, KAKENHI-PROJECT-20H03262, KAKENHI-PROJECT-18J00586, KAKENHI-PROJECT-20J40132, KAKENHI-PROJECT-19K22388, KAKENHI-PROJECT-19K16490, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06424
[Journal Article] Characterization of brown adipose tissue thermogenesis in the naked mole-rat (Heterocephalus glaber), a heterothermic mammal2020
- Author(s)
  Oiwa Yuki、Oka Kaori、Yasui Hironobu、Higashikawa Kei、Bono Hidemasa、Kawamura Yoshimi、Miyawaki Shingo、Watarai Akiyuki、Kikusui Takefumi、Shimizu Atsushi、Okano Hideyuki、Kuge Yuji、Kimura Kazuhiro、Okamatsu-Ogura Yuko、Miura Kyoko
- Journal Title
  
  Scientific Reports
  
  Volume: 10 Issue: 1 Pages: 19488-19499
- DOI
  10.1038/s41598-020-74929-6
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20KK0250, KAKENHI-PROJECT-20H00443, KAKENHI-PROJECT-19H03116, KAKENHI-PROJECT-18K19254, KAKENHI-PROJECT-19K16490
[Journal Article] 遺伝子改変マウスの作製の歴史と技術進歩2019
- Author(s)
  宮脇慎吾、立花誠
- Journal Title
  
  生産と技術
  
  Volume: Vol. 71 (4) Pages: 15-20
- NAID
  40022051021
- Data Source
  KAKENHI-PROJECT-19K16490
[Journal Article] Role of epigenetic regulation in mammalian sex determination.2019
- Author(s)
  Shingo Miyawaki, Makoto Tachibana
- Journal Title
  
  Curr Top Dev Biol.
  
  Volume: 134 Pages: 195-221
- DOI
  10.1016/bs.ctdb.2019.01.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K17924, KAKENHI-PROJECT-19K22388, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06424, KAKENHI-PROJECT-18H02419
[Journal Article] Teratoma Formation Assay for Assessing Pluripotency and Tumorigenicity of Pluripotent Stem Cells2017
- Author(s)
  Miyawaki Shingo、Okada Yohei、Okano Hideyuki、Miura Kyoko
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 7 Issue: 16
- DOI
  10.21769/bioprotoc.2518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K19465, KAKENHI-PROJECT-17K17924, KAKENHI-PUBLICLY-17H05707, KAKENHI-PROJECT-15H04278, KAKENHI-PROJECT-16K14602
[Journal Article] Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance2017
- Author(s)
  Shunsuke Kuroki, Naoki Okashita, Baba Shoko, Maeda Ryo, Shingo Miyawaki, Masashi Yano, Yamaguchi Miyoko, Kitano Satsuki, Miyachi Hitoshi, Itoh Akihiro, Yoshida Minoru and Makoto Tachibana
- Journal Title
  
  PLoS Genetics
  
  Volume: 13(9) Issue: 9 Pages: 1-22
- DOI
  10.1371/journal.pgen.1007034
- NAID
  120006812002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17924, KAKENHI-ORGANIZER-17H06423, KAKENHI-PLANNED-17H06424, KAKENHI-PROJECT-26221204, KAKENHI-PROJECT-16K18492, KAKENHI-PROJECT-16K21196
[Presentation] Cold-inducible RNA-binding protein（CIRP）遺伝子ゲノム編集マウスにおける休眠・低体温誘導2023
- Author(s)
  髙橋愛佳、白石茂菜実、堀井有希、宮脇慎吾、平田暁大、椎名貴彦、志水泰武
- Organizer
  第32回日本病態生理学会大会
- Data Source
  KAKENHI-PROJECT-22K19243
[Presentation] マウスCold-inducible RNA-binding protein 遺伝子における日内休眠時の選択的スプライシング (The alternative splicing of Cold-inducible RNA-binding protein gene in mice during daily torpor)2023
- Author(s)
  髙橋愛佳、白石茂菜実、堀井有希、宮脇慎吾、椎名貴彦、志水泰武
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K19243
[Presentation] Cold-inducible RNA-binding protein（CIRP）遺伝子ゲノム編集マウスにおける低温耐性の解析2023
- Author(s)
  髙橋愛佳、白石茂菜実、堀井有希、宮脇慎吾、平田暁大、椎名貴彦、志水泰武
- Organizer
  第70回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-22K19243
[Presentation] スンクス（Suncus murinus）における日内休眠のメカニズムの解析 (Elucidation of the daily torpor mechanism in Suncus murinus)2023
- Author(s)
  堀井有希、岡寺香南子、宮脇慎吾、椎名貴彦、志水泰武
- Organizer
  第100回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-22K19243
[Presentation] Cold-inducible RNA-binding protein（CIRP）遺伝子ゲノム編集マウスにおける日内休眠と低体温誘導2023
- Author(s)
  髙橋愛佳、白石茂菜実、堀井有希、宮脇慎吾、平田暁大、椎名貴彦、志水泰武
- Organizer
  第166回日本獣医学会学術集会
- Data Source
  KAKENHI-PROJECT-22K19243
[Presentation] 日内休眠により引き起こされるCold-inducible RNA-binding protein 遺伝子の選択的スプライシングの冬眠様変化2022
- Author(s)
  髙橋愛佳、白石茂菜実、堀井有希、宮脇慎吾、椎名貴彦、志水泰武
- Organizer
  第69回中部日本生理学会
- Data Source
  KAKENHI-PROJECT-22K19243
[Presentation] マウスSryにおける"隠れエキソン”の発見2021
- Author(s)
  宮脇慎吾、立花誠
- Organizer
  日本卵子学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16490
[Presentation] THE EFFECT OF MATERNAL DIET AND NUTRITIONAL STATUS ON MAMMALIAN SEX DETERMINATION2019
- Author(s)
  Miyawaki, S., Okashita, N., Kuroki, S. and Tachibana, M
- Organizer
  International Society for Stem Cell Research Annual Meeting 2019 (Los Angeles)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16490
[Presentation] A novel sex determination region in inverted repeat sequence of mouse Y chromosome.2019
- Author(s)
  Miyawaki, S
- Organizer
  日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K16490
[Presentation] THE EFFECT OF MATERNAL DIET AND NUTRITIONAL STATUS ON MAMMALIAN SEX DETERMINATION2019
- Author(s)
  Shingo Miyawaki, Makoto Tachibana
- Organizer
  International Society for Stem Cell Research (ISSCR)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17924
[Presentation] The effect of maternal diet and nutritional status on mammalian sex determination.2018
- Author(s)
  Miyawaki, Shingo; Kuroki, Shunsuke; Okashita, Naoki; Tachibana, Makoto
- Organizer
  The 13th International Symposium of the Institute Network for Biomedical Sciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17924

1. 正谷達謄 (70614072)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. Shimizu Yasutake (40243802)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. Tachibana Makoto (80303915)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
4. 平田暁大 (30397327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 堀井有希 (20888531)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
6. 山岸潤也 (80535328)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 山口裕嗣 (10542970)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 伊藤直人 (20334922)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 土井謙太郎 (20378798)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 内藤清惟 (30794903)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 任書晃 (80644905)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 海野年弘 (90252121)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 高島康弘 (20333552)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 山本雅裕 (00444521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 中川敬介 (90853250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 鬼頭克也 (80270974)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 大木拓究人 (30878864)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 岡田洋平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 黒木俊介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 安井博宣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Miyawaki Shingo 宮脇 慎吾

MIYAWAKI Shingo 宮脇 慎吾

Research Projects

Research Products

Co-Researchers

犬の遺伝性疾患“再現マウス”を活用したゲノム編集治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive understanding of the antiviral innate immune response elicited by latently infected protozoan parasites

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脳と大腸を機能連関させる神経回路のリモデリングとその排便異常への関与

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

致死性病原体の潜伏を可能にする野生動物の分子免疫機構

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A new interpretation of contact activation system: A host defense mechanism for hemostasis and infection control

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

犬の新たな遺伝性疾患である「消化管腫瘍性ポリポーシス」の重症化機構の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of low temperature tolerance common to mammals as a basis for induction of artificial hibernation.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Revision of the mechanism of action of the mammalian sex-determining gene Sry and its genome evolutionary process

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of Cryptic exon by long RNA sequencingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

elucidate the causes of genetic diseases in dogs using genome-edited micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

EFFECT OF MATERNAL DIET AND NUTRITIONAL STATUS ON MAMMALIAN SEX DETERMINATIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The influence of maternal nutrition on sex determinationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] The Evolutionary Aspects of the Mammalian Sex-Determining Gene SRY.2023

Author(s)

Total Pages

Miyawaki Shingo 宮脇慎吾

MIYAWAKI Shingo 宮脇慎吾