TSURUBUCHI TAKAO 鶴淵隆夫

… Alternative Names

Tsurubuchi Takao 鶴淵隆夫

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Researcher Number	70778901
Other IDs
Affiliation (Current)	2025: 筑波大学, 医学医療系, 准教授
Affiliation (based on the past Project Information) *help	2016 – 2024: 筑波大学, 医学医療系, 講師
Review Section/Research Field	Principal Investigator Basic Section 56010:Neurosurgery-related / Neurosurgery Except Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related / Basic Section 52040:Radiological sciences-related / Basic Section 56010:Neurosurgery-related / Neurosurgery
Keywords	Principal Investigator 基礎的研究 / 早期胎内分子診断 / エピジェネティック機序 / 生物学的マーカー / 神経管閉鎖不全症 / 再発・増悪予測 / 悪性脳脊髄腫瘍 / FBPA PET / 分子代謝イメージング / 基礎研究 … More / 中性子捕捉療法 / 細胞内取り込み試験 / in vitro study / 低分子化合物 / ホウ素多価イオン / 平面三配位ホウ素 / 血液 / 葉酸 / 次世代シーケンサー / エピジェネティクマーカー / 早期胎内分子診断法の確立 / メタボローム解析 / バイオマーカー / 髄膜瘤 / 血清 / 羊水 / メタボローム / 胎内分子診断 / 母体血清 / 母体羊水 / 早期診断 / 脊髄髄膜瘤 / 神経管閉鎖不全 / 早期胎内診断 / 協力病院 / 倫理委員会 / 培養条件 / 培地 / 羊水幹細胞 … More Except Principal Investigator BNCT / 悪性脳腫瘍 / ホウ素中性子捕捉療法 / liposomes / tumor targeting / gold / boron / nanoparticles / glioma / 脳腫瘍 / 粒子線治療 / 中性子捕捉療法 / active tumor targeting / carboranes / 放射線療法 / 放射線力学的治療 / 免疫療法 / 悪性神経膠腫 / カーボンナノホーン / BN-CNH / dosimetry / 放射線治療 / PEGリポソーム / 腫瘍増殖抑制試験 / 担がんマウス / 血中滞留性 / 薬物動態 / ホウ素イメージング / アルファオートラジオグラフィー / ドラッグデリバリーシステム / リポソーム / アルファ線 / 臨床的研究 / 基礎的研究 / 加速器型中性子源 / 病院併設型 / ホウ素化合物 / 病院併設型加速器の開発 / 小型加速器型中性子源 / 新規ホウ素化合物の基礎的研究 / 病院併設型小型加速器中性子源 / 基礎的・臨床的研究 / 病院内BNCT / 小型加速器中性子線源 / 定位的治療 / 内視鏡手術 / 低侵襲手術 / 低侵襲治療 / 低侵襲脳腫瘍治療 / レーザー内視鏡 / レーザー照射治療 / 光線力学療法 / ホウ素中性子補足療法 / 加速器中性子線源 / 脳腫瘍学 / 細胞照射実験 / 線量評価 / モンテカルロ / 加速器 / 生物学的基礎実験 / 治療計画システム / 病院内小型加速器 Less

Elucidation and Overcoming the Mechanism of Immune Cell Inactivation after Combination of Advanced Local Therapy and Immunotherapy for Glioblastoma
- Principal Investigator
  
  石川栄一
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Prediction of relapse of malignant brain and spinal tumors at pretreatment stage by molecular metabolic PET imagingPrincipal Investigator
- Principal Investigator
  
  鶴淵隆夫
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Development of a novel multifunctional nanoliposome-based system for maintaining active agent concentration in tumor tissue during boron-neutron capture therapy
- Principal Investigator
  
  ザボロノクアレクサンドル
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Tsukuba
中性子捕捉療法のための平面三配位ホウ素化合物の開発研究Principal Investigator
- Principal Investigator
  
  鶴淵隆夫
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Development of novel tumor-targeting nanoparticles for malignant brain tumor neutron capture therapy and diagnosis
- Principal Investigator
  
  Zaboronok Alexander
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  University of Tsukuba
Boron distribution study for newly developed BNCT agents
- Principal Investigator
  
  Nakai Kei
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Tsukuba
Establishment of early intrauterine molecular diagnostic markers of neural tube defectsPrincipal Investigator
- Principal Investigator
  
  TSURUBUCHI TAKAO
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Fundamental studies for application of small linear accelerator to in-hospital BNCT
- Principal Investigator
  
  Matsumura Akira
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  University of Tsukuba
Study of new boron carriers using carbon nano horns
- Principal Investigator
  
  Yoshida Fumiyo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  University of Tsukuba
Amniotic fluid and serum biomarkers from women with neural tube defect-affected pregnanciesPrincipal Investigator
- Principal Investigator
  
  Tsurubuchi Takao
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurosurgery
- Research Institution
  University of Tsukuba
Stereotactic photodynamic therapy using minimally invasive laser irradiating device
- Principal Investigator
  
  Akutsu Hiroyoshi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Tsukuba
The fundamental and preclinical study about accelerator-based boron neutron capture therapy in hospital
- Principal Investigator
  
  Matsumura Akira
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Neurosurgery
- Research Institution
  University of Tsukuba

All 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy2021
- Author(s)
  Shirakawa Makoto、Zaboronok Alexander、Nakai Kei、Sato Yuhki、Kayaki Sho、Sakai Tomonori、Tsurubuchi Takao、Yoshida Fumiyo、Nishiyama Takashi、Suzuki Minoru、Tomida Hisao、Matsumura Akira
- Journal Title
  
  Cells
  
  Volume: 10 Issue: 12 Pages: 3421-3421
- DOI
  10.3390/cells10123421
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K18409, KAKENHI-PROJECT-18H02909
[Journal Article] Difference in BPA uptake between glioma stem-like cells and their cancerous cells2020
- Author(s)
  Yoshida Fumiyo、Kurita Tadashi、Endo Keita、Nakai Kei、Shirakawa Makoto、Zaboronok Alexander、Tsurubuchi Takao、Ishikawa Eiichi、Matsumura Akira
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 164 Pages: 109234-109234
- DOI
  10.1016/j.apradiso.2020.109234
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07705
[Journal Article] Evaluation of a Novel Boron-Containing α-d-Mannopyranoside for BNCT2020
- Author(s)
  Tsurubuchi Takao、Shirakawa Makoto、Kurosawa Wataru、Matsumoto Kayo、Ubagai Risa、Umishio Hiroshi、Suga Yasuyo、Yamazaki Junko、Arakawa Akihiro、Maruyama Yutaka、Seki Takuya、Shibui Yusuke、Yoshida Fumiyo、Zaboronok Alexander、Suzuki Minoru、Sakurai Yoshinori、Tanaka Hiroki、Nakai Kei、Ishikawa Eiichi、Matsumura Akira
- Journal Title
  
  Cells
  
  Volume: 9 Issue: 5 Pages: 1277-1277
- DOI
  10.3390/cells9051277
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K07705
[Journal Article] Boron analysis and imaging of cells with 2-hr BPA exposure by using micro-proton particle-induced gamma-ray emission (PIGE)2020
- Author(s)
  Nakai Kei、Endo Keita、Yoshida Fumiyo、Koka Masashi、Yamada Naoto、Satoh Takahiro、Tsurubuchi Takao、Matsumura Akira、Matsumoto Yoshitaka、Sakurai Hideyuki
- Journal Title
  
  Applied Radiation and Isotopes
  
  Volume: 165 Pages: 109334-109334
- DOI
  10.1016/j.apradiso.2020.109334
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08194, KAKENHI-PROJECT-18K07705
[Journal Article] 椎弓余剰骨の急速な増大を認めた二分脊椎類縁疾患の一例2018
- Author(s)
  鶴淵隆夫, 室井愛, 稲垣隆介, 山本哲哉, 松村明
- Journal Title
  
  小児の脳神経
  
  Volume: 43（１） Pages: 25-29
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06664
[Journal Article] 脊髄髄膜瘤に伴う脊柱変形に関する臨床的評価.2018
- Author(s)
  鶴淵隆夫、室井愛、稲垣隆介、山本哲哉、松村明
- Journal Title
  
  小児の脳神経
  
  Volume: 43 Pages: 455-460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08935
[Journal Article] 椎弓余剰骨の急速な増大を認めた二分脊椎類縁疾患の一例.2018
- Author(s)
  鶴淵隆夫、室井愛、稲垣隆介、山本哲哉、松村明
- Journal Title
  
  小児の脳神経
  
  Volume: 43 Pages: 1-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08935
[Journal Article] 椎弓余剰骨の急速な増大を認めた二分脊椎類縁疾患の一例2017
- Author(s)
  鶴淵　隆夫、稲垣　隆介、室井　愛、坂本　規彰、大谷　明夫、大谷　紀子、山本　哲哉、松村　明
- Journal Title
  
  小児の脳神経
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16H06664
[Presentation] 金ナノ粒子を用いた悪性腫瘍のホウ素中性子捕捉療法におけるin situ吸収線量評価.2022
- Author(s)
  Zaboronok A、Taskaev S、Volkova O、Mechetina L、Kasatova A、Sycheva T、中井　啓、 Kasatov D、Makarov A、Shchudlo I、鶴淵隆夫、Kanygin V、 Kichigin A、石川栄一、松村明
- Organizer
  第18回日本中性子捕捉療法学会学術大会, 2022-10-29 (茨城, つくば市)
- Data Source
  KAKENHI-PROJECT-20K07672
[Presentation] BPAを構成成としたイオン液体のin vitroおよびin vivo評価2022
- Author(s)
  坂居知憲、寺田莉子、鮫島未森、佐藤雄己、Alexander Zaboronok、鶴淵隆夫、中井啓、熊田博明、榮武二、松村明、亀川展幸、竹内亮太、堀均、鈴木実、白川真
- Organizer
  第18回日本中性子捕捉療法学会
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] BPA を構成成分としたイオン液体の開発2022
- Author(s)
  白川真, 河本紗季, 河上清香, 坂居知憲, 佐藤雄己, Alexander Z, 鶴淵隆夫, 中井啓, 熊田博明, 榮武二, 松村明, 亀川展幸, 竹内亮太, 堀均, 鈴木実
- Organizer
  第 18 回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] BPA を構成成分としたイオン液体の in vitro および in vivo 評価2022
- Author(s)
  坂居知憲, 寺田莉子, 鮫島未森, 佐藤雄己, Alexander Z, 鶴淵隆夫, 中井啓, 熊田博明, 榮武二, 松村明, ⻲川展幸, 竹内亮太, 堀均, 鈴木実, 白川真
- Organizer
  第 18 回日本中性子捕捉療法学会学術大会
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] 元素状ホウ素ナノ粒子を用いた加速器型BNCT実験2022
- Author(s)
  Zaboronok A、Khaptakhanova P、Uspenskii S、Bekarevich R、Mechetina L、Volkova O、Kanygin V、石川栄一、Kasatova A、 Kasatov D、Shchudlo I、Sycheva T、Taskaev S、鶴淵隆夫、松村明
- Organizer
  第18回日本中性子捕捉療法学会学術大会, 2022-10-29 (茨城, つくば市)
- Data Source
  KAKENHI-PROJECT-20K07672
[Presentation] Evaluation of novel boron cluster conjugated PEG derivative for BNCT2021
- Author(s)
  Shirakawa M, Sato Y, Sakai T, Terada R, Sameshima M, Kamegawa N, Takeuchi R, Nakai K, Zaboronok A, Tsurubuchi T, Yoshida F, Kumada H, Sakae T, Suzuki M, Hori H and Matsumura A
- Organizer
  19th International Congress of Neutron Capture Therapy (ICNCT-19)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] Evaluation of novel boron cluster conjugated PEG derivative for BNCT2021
- Author(s)
  Shirakawa M, Sato Y, Sakai T, Terada R, Sameshima M, Kamegawa N, Takeuchi R, Nakai K, Zaboronok A, Tsurubuchi T, Yoshida F, Kumada H, Sakae T, Suzuki M, Hori H, Matsumura A
- Organizer
  19th International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] In vivo Evaluation of Novel Boron containing compound A-1 for BNCT2019
- Author(s)
  Tsurubuchi T; Matsumoto K; Ubagai R; Nakai Kei; Yoshida F...
- Organizer
  YBNCT to Helsinki 2019(FINISH SOCIETY FOR NEUTRON CAPTURE THERAPY Offers to organize the 10th YBNCT meeting)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] Absorbed dose evaluation using complex boron compounds for BNCT2019
- Author(s)
  Zaboronok A; Uspenskii S; Khaptakhanova P; Zelenetskii AN; Kurkin T; Volkova O; Mechetina L; Taranin A; Selyanin M; Taskaev S; Kanygin V; Mathis BJ; Tsurubuchi T; Matsumura A
- Organizer
  1st Ru BNCT CONFERENCE
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] Hybrid gold and boron nanoparticles for treatment and boron dose estimation in boron neutron capture therapy for malignant glioma2018
- Author(s)
  Alexander Zaboronok, Sergey Taskaev, Vladimir Kanygin, Timofei Bykov, Kazutaka Mitsuishi, Eisuke Sato, Kei Nakai,Takao Tsurubuchi, Fumiyo Yoshida, Eiichi Ishikawa, Bryan J. Mathis, Tetsuya Yamamoto,Akira Matsumura
- Organizer
  International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07705
[Presentation] Hybrid gold and boron nanoparticles for treatment and boron dose estimation in boron neutron capture therapy for malignant glioma2018
- Author(s)
  Alexander Zaboronok, Kei Nakai,Takao Tsurubuchi, Fumiyo Yoshida, Eiichi Ishikawa, Bryan J. Mathis, Tetsuya Yamamoto, Akira Matsumura
- Organizer
  International Congress on Neutron Capture Therapy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02909
[Presentation] 脊髄髄膜瘤に伴う脊柱変形に関する臨床学的評価2017
- Author(s)
  2.鶴淵隆夫、室井　愛、津田恭治、稲垣隆介、井原　哲、山本哲哉、松村　明
- Organizer
  第45回日本小児神経外科学会
- Data Source
  KAKENHI-PROJECT-16H06664
[Presentation] Amniotic fluid and serum biomarkers from women with neural tube defect-affected pregnancies: a case study for myelomeningocele and anencephaly: clinical article2017
- Author(s)
  Takao Tsurubuchi, Shunsuke Ichi, Kyu-won Shim, William Norkett., Elise Allender, Barbara Mania-Farnell, Tadanori Tomita, David G. McLone, Norman Ginsberg, Shekhar Mayanil, Eiichi Ishikawa, Akira Matsumura
- Organizer
  The 29th KSPN-JSPN joint meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06664
[Presentation] 脊髄髄膜瘤に伴う脊柱変形に関する臨床学的評価2017
- Author(s)
  5.鶴淵隆夫、室井　愛、津田恭治、稲垣隆介、井原　哲、山本哲哉、松村　明
- Organizer
  第76回日本脳神経外科学会
- Data Source
  KAKENHI-PROJECT-16H06664

1. Nakai Kei (50436284)

# of Collaborated Projects: 8 results

# of Collaborated Products: 12 results
2. Zaboronok Alexander (20723117)

# of Collaborated Projects: 4 results

# of Collaborated Products: 5 results
3. 白川真 (40707759)

# of Collaborated Projects: 3 results

# of Collaborated Products: 3 results
4. Matsumura Akira (90241819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
5. Yoshida Fumiyo (30261811)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. 熊田博明 (30354913)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
7. 山本哲哉 (30375505)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MATHIS BRYAN (80794635)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 石川栄一 (30510169)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. Akutsu Hiroyoshi (20547955)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 磯辺智範 (70383643)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 岡潔 (80354661)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 室井愛 (10709215)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. 濱田洋実 (60261799)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 八木洋也 (70625623)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 阿部春奈 (10831927)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 中村浩之 (30274434)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 松本孔貴 (70510395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
19. 湯田坂雅子 (70159226)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岡崎俊也 (90314054)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 田中直樹 (00844672)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 三木俊一郎 (10774036)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 松田真秀 (30614333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 松井裕史 (70272200)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 杉井成志 (10851090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 籏野健太郎 (50228475)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

TSURUBUCHI TAKAO 鶴淵 隆夫

Tsurubuchi Takao 鶴淵 隆夫

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Prediction of relapse of malignant brain and spinal tumors at pretreatment stage by molecular metabolic PET imagingPrincipal Investigator

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中性子捕捉療法のための平面三配位ホウ素化合物の開発研究Principal Investigator

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Establishment of early intrauterine molecular diagnostic markers of neural tube defectsPrincipal Investigator

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Amniotic fluid and serum biomarkers from women with neural tube defect-affected pregnanciesPrincipal Investigator

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[Journal Article] A Novel Boron Lipid to Modify Liposomal Surfaces for Boron Neutron Capture Therapy2021

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[Journal Article] Difference in BPA uptake between glioma stem-like cells and their cancerous cells2020

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Data Source

[Journal Article] Evaluation of a Novel Boron-Containing α-d-Mannopyranoside for BNCT2020

TSURUBUCHI TAKAO 鶴淵隆夫

Tsurubuchi Takao 鶴淵隆夫