SHIGIYAMA Fumika 鴫山文華

Researcher Number	70808188
Affiliation (Current)	2025: 金沢医科大学, 医学部, 非常勤講師
Affiliation (based on the past Project Information) *help	2022 – 2024: 金沢医科大学, 医学部, 非常勤講師 2018 – 2021: 東邦大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 54040:Metabolism and endocrinology-related Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 52010:General internal medicine-related
Keywords	Principal Investigator 耐糖能異常 / 脂肪肝 / 2型糖尿病 / 肝インスリン感受性 / 肝インスリン抵抗性 / 肝脂肪蓄積 / インスリン抵抗性 / Elovl3 / 睡眠障害 Except Principal Investigator 脂肪との共存 … More / 肝臓実質体積 / 肝脂肪 / 除脂肪肝臓体積 / 肝脂肪量 / 肝インスリン感受性 / 非アルコール性脂肪肝 / 肝臓体積 / インスリン感受性 / 脂肪肝 / 介入法 / 糖尿病 / 生活の質 / アンケート調査 / 睡眠障害 / 2型糖尿病 Less

脂肪との共存の実現へ向けたSLC28A1の予防・治療標的としての可能性の追究
- Principal Investigator
  
  熊代尚記
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa Medical University
肝インスリン抵抗性におけるRho family GTPase 2の病的意義の解明Principal Investigator
- Principal Investigator
  
  鴫山文華
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Kanazawa Medical University
Exploration of hepatic parenchymal regulatory mechanisms to realize diabetes suppression strategy via coexistence with fat
- Principal Investigator
  
  KUMASHIRO Naoki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Kanazawa Medical University
  Toho University
Investigation on methods of intervention in sleep disorder improving QOL of diabetes patients
- Principal Investigator
  
  HIROSE Takahisa
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Toho University
Mechanisms of hepatic steatosis and insulin resistance induced by sleep deprivation in micePrincipal Investigator
- Principal Investigator
  
  SHIGIYAMA Fumika
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54040:Metabolism and endocrinology-related
- Research Institution
  Toho University

All 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Empagliflozin versus sitagliptin for ameliorating intrahepatic lipid content and tissue‐specific insulin sensitivity in patients with early‐stage type 2 diabetes with non‐alcoholic fatty liver disease: A prospective randomized study2023
- Author(s)
  Hiruma Shigenori、Shigiyama Fumika、Kumashiro Naoki
- Journal Title
  
  Diabetes, Obesity and Metabolism
  
  Volume: - Issue: 6 Pages: 1576-1588
- DOI
  10.1111/dom.15006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04112
[Journal Article] A prospective randomized study comparing effects of empagliflozin to sitagliptin on cardiac fat accumulation, cardiac function, and cardiac metabolism in patients with early-stage type 2 diabetes: the ASSET study2021
- Author(s)
  Hiruma S, Shigiyama F, Hisatake S, Mizumura S, Shiraga N, Hori M, Ikeda T, Hirose T, Kumashiro N
- Journal Title
  
  Cardiovascular Diabetology
  
  Volume: 20 Issue: 1 Pages: 32-32
- DOI
  10.1186/s12933-021-01228-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H04112
[Journal Article] Simplification of complex insulin regimens using canagliflozin or liraglutide in patients with well‐controlled type 2 diabetes: A 24‐week randomized controlled trial2021
- Author(s)
  Ando Yasuyo、Shigiyama Fumika、Hirose Takahisa、Kumashiro Naoki
- Journal Title
  
  Journal of Diabetes Investigation
  
  Volume: 12 Issue: 10 Pages: 1816-1826
- DOI
  10.1111/jdi.13533
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04112
[Journal Article] Changes in subjective sleep quality in patients with type 2 diabetes who did not use Sleep agents: a cross-sectional study according to age and clinical background2021
- Author(s)
  Yoshikawa Fukumi、Kumashiro Naoki、Shigiyama Fumika、Miyagi Masahiko、Ando Yasuyo、Uchino Hiroshi、Hirose Takahisa
- Journal Title
  
  Diabetology International
  
  Volume: 13 Issue: 1 Pages: 142-147
- DOI
  10.1007/s13340-021-00516-3
- NAID
  40022802881
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H04112
[Journal Article] 脂肪との共存を実現する肝インスリン感受性保持機構の追究2020
- Author(s)
  熊代尚記, 鴫山文華, 五十嵐弘之, 蛭間重典, 弘世貴久
- Journal Title
  
  糖尿病合併症
  
  Volume: 34 Pages: 186-193
- Data Source
  KAKENHI-PROJECT-20H04112
[Journal Article] Whole hepatic lipid volume quantification and color mapping by multi-slice and multi-point magnetic resonance imaging2019
- Author(s)
  Igarashi H, Shigiyama F, Wakui N, Nagai H, Shibuya K, Shiraga N, Hirose T, Kumashiro N
- Journal Title
  
  Hepatol Res
  
  Volume: 2019 Dec Issue: 12 Pages: 1374-1385
- DOI
  10.1111/hepr.13408
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16213, KAKENHI-PROJECT-17H02180
[Journal Article] メトホルミンの肝臓におけるミトコンドリア complex I 阻害非依存性作用2019
- Author(s)
  渕上彩子, 鴫山文華, 熊代尚記
- Journal Title
  
  内分泌・糖尿病・代謝内科
  
  Volume: 49 Pages: 184-188
- Open Access
- Data Source
  KAKENHI-PROJECT-18K16213
[Journal Article] Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice2018
- Author(s)
  Shigiyama F, Kumashiro N, Tsuneoka Y, Igarashi H, Yoshikawa F, Kakehi S, Funato H, Hirose T
- Journal Title
  
  Am J Physiol Endocrinol Metab
  
  Volume: 315 Issue: 5 Pages: E848-E858
- DOI
  10.1152/ajpendo.00072.2018
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K16213, KAKENHI-PUBLICLY-17H05583, KAKENHI-PROJECT-17H02180, KAKENHI-PROJECT-17H04023
[Presentation] 異所性脂肪蓄積と組織特異的インスリン感受性に着目したNAFLD合併早期２型糖尿病の治療戦略2022
- Author(s)
  蛭間重典, 鴫山文華, 和久井紀貴, 渕上彩子, 白神伸之, 堀正明, 田村好史, 綿田裕孝, 弘世貴久, 熊代尚記
- Organizer
  第8回肝臓と糖尿病・代謝研究会
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] 日本人非アルコール性脂肪肝における肝インスリン感受性規定因子の探索2022
- Author(s)
  鴫山文華, 蛭間重典, 熊代尚記
- Organizer
  第43回日本肥満学会・第40回日本肥満症治療学会学術集会
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] 異所性脂肪蓄積と組織特異的インスリン感受性に着目したNAFLD合併早期2型糖尿病の治療戦略(柳瀬武司奨学基金受賞講演)2022
- Author(s)
  蛭間重典, 鴫山文華, 和久井紀貴, 渕上彩子, 白神伸之, 堀　正明, 田村好史, 綿田裕孝, 弘世貴久, 熊代尚記
- Organizer
  第160回東邦医学会例会
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] 日本人非アルコール性脂肪肝における肝インスリン感受性規定因子の探索2022
- Author(s)
  鴫山文華
- Organizer
  肥満学会
- Data Source
  KAKENHI-PROJECT-22K16434
[Presentation] 脂肪肝・インスリン抵抗性に対するRho family GTPase2抑制効果の検討2022
- Author(s)
  鴫山文華, 小林瑠璃, 中村直美, 渕上彩子, 弘世貴久, 熊代尚記
- Organizer
  第95回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] Impact of hepatic elovl3 on sleep deprivation induced hepatic steatosis and glucose intolerance2020
- Author(s)
  Fumika Shigiyama
- Organizer
  56th EASD (European Association for theStudy of Diabetes) Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16213
[Presentation] 層別解析による2型糖尿病における主観的睡眠関連指標の年代別変化および臨床背景の検討.2020
- Author(s)
  吉川芙久美, 熊代尚記, 鴫山文華, 宮城匡彦, 安藤恭代, 内野泰, 弘世貴久
- Organizer
  第63回日本糖尿病学会年次学術集会, Web開催, 2020.10
- Data Source
  KAKENHI-PROJECT-18K07481
[Presentation] 日本人NAFLDの網羅的解析による新規の肝インスリン感受性規定因子、徐脂肪肝臓体積の同定2020
- Author(s)
  鴫山文華、五十嵐弘之、蛭間重典、弘世貴久、熊代尚記
- Organizer
  第93回日本内分泌学会学術総会
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] 日本人NAFLDの網羅的解析による新規の肝インスリン感受性規定因子、徐脂肪肝臓体積の同定2020
- Author(s)
  鴫山文華、熊代尚記、蛭間重典、渕上彩子、弘世貴久
- Organizer
  第21回日本内分泌学会関東甲信越支部学術集会
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] Impact of hepatic elovl3 on sleep deprivation induced hepatic steatosis and glucose intolerance2020
- Author(s)
  Shigiyama F, Fuchigami A, Hirose T, Kumashiro N
- Organizer
  56th Annual Meeting of the European Association for the Study of Diabetes (EASD)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] Comparison of empagliflozin and sitagliptin on ectopic fat accumulation and tissue-specific insulin sensitivity2020
- Author(s)
  Hiruma S, Shigiyama F, Hisatake S, Mizumura S, Shiraga N, Hori M, Ikeda T, Hirose T, Kumashiro N
- Organizer
  80th American Diabetes Association Scientific Sessions (ADA)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H04112
[Presentation] 日本人NAFLDの網羅的解析による新規の肝インスリン感受性規定因子、徐脂肪肝臓体積の同定2019
- Author(s)
  鴫山文華、熊代尚記、五十嵐弘之、蛭間重典、渋谷和俊、弘世貴久
- Organizer
  第62回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-18K16213
[Presentation] Impact of lean hepatic volume on hepatic insulin resistance in human NAFLD2019
- Author(s)
  Igarashi H, Shigiyama F, Hiruma S, Hirose T, Kumashiro N
- Organizer
  79th American Diabetes Association Scientific Sessions
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16213
[Presentation] Mechanisms of Hepatic Steatosis and Insulin Resistance Induced by Sleep Deprivation in Mice2018
- Author(s)
  Shigiyama F, Kumashiro N, Yoshikawa F, Tsuneoka Y, Funato H, Hirose T
- Organizer
  78th Scientific Sessions American Diabetes Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16213
[Presentation] 肝脂肪蓄積時の肝インスリン感受性保持機構の探求2018
- Author(s)
  鴫山文華、熊代尚記、弘世貴久
- Organizer
  第36回内分泌代謝学サマーセミナー
- Invited
- Data Source
  KAKENHI-PROJECT-18K16213

1. KUMASHIRO Naoki (20535207)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
2. HIROSE Takahisa (40384119)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
3. 和久井紀貴 (20385933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 野崎雄一 (80468165)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHIGIYAMA Fumika 鴫山 文華

Research Projects

Research Products

Co-Researchers

脂肪との共存の実現へ向けたSLC28A1の予防・治療標的としての可能性の追究

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

肝インスリン抵抗性におけるRho family GTPase 2の病的意義の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Exploration of hepatic parenchymal regulatory mechanisms to realize diabetes suppression strategy via coexistence with fat

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation on methods of intervention in sleep disorder improving QOL of diabetes patients

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanisms of hepatic steatosis and insulin resistance induced by sleep deprivation in micePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Empagliflozin versus sitagliptin for ameliorating intrahepatic lipid content and tissue‐specific insulin sensitivity in patients with early‐stage type 2 diabetes with non‐alcoholic fatty liver disease: A prospective randomized study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A prospective randomized study comparing effects of empagliflozin to sitagliptin on cardiac fat accumulation, cardiac function, and cardiac metabolism in patients with early-stage type 2 diabetes: the ASSET study2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Simplification of complex insulin regimens using canagliflozin or liraglutide in patients with well‐controlled type 2 diabetes: A 24‐week randomized controlled trial2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Changes in subjective sleep quality in patients with type 2 diabetes who did not use Sleep agents: a cross-sectional study according to age and clinical background2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] 脂肪との共存を実現する肝インスリン感受性保持機構の追究2020

Author(s)

Journal Title

Data Source

[Journal Article] Whole hepatic lipid volume quantification and color mapping by multi-slice and multi-point magnetic resonance imaging2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] メトホルミンの肝臓におけるミトコンドリア complex I 阻害非依存性作用2019

Author(s)

Journal Title

Data Source

[Journal Article] Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] 異所性脂肪蓄積と組織特異的インスリン感受性に着目したNAFLD合併早期２型糖尿病の治療戦略2022

Author(s)

Organizer

Data Source

[Presentation] 日本人非アルコール性脂肪肝における肝インスリン感受性規定因子の探索2022

Author(s)

Organizer

SHIGIYAMA Fumika 鴫山文華

[Presentation] 日本人非アルコール性脂肪肝における肝インスリン感受性規定因子の探索2022