Iikuni Shimpei 飯國慎平

Researcher Number	70837731
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2022: 京都大学, 薬学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 52040:Radiological sciences-related Except Principal Investigator Basic Section 52040:Radiological sciences-related
Keywords	Principal Investigator がん低酸素 / ラジオセラノスティクス / 炭酸脱水酵素-IX / 固形腫瘍 / イメージング / セラノスティクス / 炭酸脱水酵素IX Except Principal Investigator パーキンソン病 / レビー小体病 / イメージング / αシヌクレイン

がん免疫療法の治療効果予測に資する新規パーフォリンイメージング法の開発Principal Investigator
- Principal Investigator
  
  飯國慎平
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Development of nuclear medicine imaging method targeting alfa-synuclein aggregates for diagnosis and treatment of Lewy body disease.
- Principal Investigator
  
  Ono Masahiro
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University
Development of coumarin-based theranostic agents targeting carbonic anhydrase-IXPrincipal Investigator
- Principal Investigator
  
  Iikuni Shimpei
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52040:Radiological sciences-related
- Research Institution
  Kyoto University

All 2022 2021 2020

All Journal Article Presentation

[Journal Article] Synthesis and evaluation of novel radioiodinated phenylbenzofuranone derivatives as α-synuclein imaging probes2022
- Author(s)
  Akasaka T, Watanabe H, Kaide S, Iikuni S, Hasegawa M, Ono M
- Journal Title
  
  Bioorg Med Chem Lett
  
  Volume: 64 Pages: 128679-128679
- DOI
  10.1016/j.bmcl.2022.128679
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622
[Journal Article] Synthesis and Evaluation of 18F-Labeled Chalcone Analogue for Detection of α-Synuclein Aggregates in the Brain Using the Mouse Model2022
- Author(s)
  Kaide S, Watanabe H, Iikuni S, Hasegawa M, Ono M.
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 13 Issue: 20 Pages: 2982-2990
- DOI
  10.1021/acschemneuro.2c00473
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622
[Journal Article] Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology2022
- Author(s)
  Kaide S, Watanabe H, Iikuni S, Hasegawa M, Itoh K, Ono M
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 13 Issue: 1 Pages: 16-26
- DOI
  10.1021/acschemneuro.1c00441
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622, KAKENHI-PROJECT-20J14694
[Journal Article] Synthesis and evaluation of 68Ga-labeled imidazothiadiazole sulfonamide derivatives for PET imaging of carbonic anhydrase-IX2021
- Author(s)
  Nakashima Kazuma、Iikuni Shimpei、Okada Yuya、Watanabe Hiroyuki、Shimizu Yoichi、Nakamoto Yuji、Ono Masahiro
- Journal Title
  
  Nuclear Medicine and Biology
  
  Volume: 93 Pages: 46-53
- DOI
  10.1016/j.nucmedbio.2020.11.008
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17166
[Journal Article] Synthesis and evaluation of indium-111-labeled imidazothiadiazole sulfonamide derivative for single photon emission computed tomography imaging targeting carbonic anhydrase-IX2020
- Author(s)
  Iikuni Shimpei、Okada Yuya、Shimizu Yoichi、Watanabe Hiroyuki、Ono Masahiro
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 14 Pages: 127255-127255
- DOI
  10.1016/j.bmcl.2020.127255
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17166
[Journal Article] Identification and Evaluation of Bisquinoline Scaffold as a New Candidate for α-Synuclein-PET Imaging2020
- Author(s)
  Kaide S, Watanabe H, Shimizu Y, Iikuni S, Nakamoto Y, Hasegawa M, Itoh K, Ono M.
- Journal Title
  
  ACS Chem Neurosci
  
  Volume: 11 Issue: 24 Pages: 4254-4261
- DOI
  10.1021/acschemneuro.0c00523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03622, KAKENHI-PROJECT-20J14694
[Journal Article] Synthesis and evaluation of novel technetium-99m-hydroxamamide complex based on imidazothiadiazole sulfonamide targeting carbonic anhydrase-IX for tumor imaging2020
- Author(s)
  Iikuni Shimpei、Kitano Anna、Watanabe Hiroyuki、Shimizu Yoichi、Ono Masahiro
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 30 Issue: 22 Pages: 127596-127596
- DOI
  10.1016/j.bmcl.2020.127596
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K17166
[Presentation] αシヌクレインイメージングプローブの開発を目的とした新規18F標識スチリルキノリン/キノキサリン誘導体の合成と評価2021
- Author(s)
  中川航平, 渡邊裕之, 貝出翔, 飯國慎平, 志水陽一, 小野正博
- Organizer
  第4回日本核医学会分科会放射性薬品科学研究会/第19回放射性医薬品・画像診断薬研究会（仙台)
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] カルコン類縁体を基盤としたαシヌクレイン標的PETイメージングプローブの開発2021
- Author(s)
  貝出翔, 渡邊裕之, 飯國慎平, 志水陽一, 長谷川成人, 伊東恭子, 小野正博
- Organizer
  第61回日本核医学会学術総会（名古屋）
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] αシヌクレインイメージングプローブの開発を目的とした放射性ヨウ素標識オーロン誘導体の合成と評価2021
- Author(s)
  赤坂貴浩, 渡邊裕之, 貝出翔, 飯國慎平, 小野正博
- Organizer
  第18回次世代を担う若手のためのフィジカル・ファーマフォーラム (仙台)
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] 神経変性疾患における脳タンパク質凝集体を標的とした核医学イメージング法の開発2021
- Author(s)
  貝出翔, 渡邊裕之, 飯國慎平, 小野正博
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] αシヌクレインの生体イメージングを目的とした放射性ヨウ素標識スチリルキノキサリン誘導体の合成および評価2021
- Author(s)
  中川航平, 渡邊裕之, 貝出翔, 飯國慎平, 長谷川成人, 伊東恭子, 小野正博
- Organizer
  日本薬学会第141年会
- Data Source
  KAKENHI-PROJECT-20H03622
[Presentation] イミダゾチアジアゾールスルホンアミド骨格を導入した新規99mTc-ヒドロキサムアミド錯体の炭酸脱水酵素IXイメージングプローブとしての有用性評価2020
- Author(s)
  北野杏奈, 飯國慎平, 渡邊裕之, 志水陽一, 小野正博
- Organizer
  日本薬学会第140年会 (京都)
- Data Source
  KAKENHI-PROJECT-19K17166
[Presentation] 炭酸脱水酵素IXのPETイメージングを目的とした放射性ガリウム標識イミダゾチアジアゾールスルホンアミド誘導体の合成と基礎的評価2020
- Author(s)
  中島一磨, 飯國慎平, 岡田祐哉, 渡邊裕之, 志水陽一, 小野正博
- Organizer
  日本薬学会第140年会 (京都)
- Data Source
  KAKENHI-PROJECT-19K17166
[Presentation] 炭酸脱水素酵素IXを標的とした新規68Ga標識化合物の合成と評価2020
- Author(s)
  中島一磨, 飯國慎平, 岡田祐哉, 渡邊裕之, 志水陽一, 小野正博
- Organizer
  第60回日本核医学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17166
[Presentation] 腎集積低減を目指した炭酸脱水酵素IXを標的とする放射性金属錯体の合成と評価2020
- Author(s)
  岡田祐哉, 飯國慎平, 渡邊裕之, 志水陽一, 小野正博
- Organizer
  日本薬学会第140年会 (京都)
- Data Source
  KAKENHI-PROJECT-19K17166

1. Ono Masahiro (80336180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
2. 渡邊裕之 (40710786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 9 results
3. 志水陽一 (90634212)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results

Iikuni Shimpei 飯國 慎平

Research Projects

Research Products

Co-Researchers

がん免疫療法の治療効果予測に資する新規パーフォリンイメージング法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of nuclear medicine imaging method targeting alfa-synuclein aggregates for diagnosis and treatment of Lewy body disease.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of coumarin-based theranostic agents targeting carbonic anhydrase-IXPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Synthesis and evaluation of novel radioiodinated phenylbenzofuranone derivatives as α-synuclein imaging probes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and Evaluation of 18F-Labeled Chalcone Analogue for Detection of α-Synuclein Aggregates in the Brain Using the Mouse Model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Chalcone Analogue as New Candidate for Selective Detection of α-Synuclein Pathology2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and evaluation of 68Ga-labeled imidazothiadiazole sulfonamide derivatives for PET imaging of carbonic anhydrase-IX2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and evaluation of indium-111-labeled imidazothiadiazole sulfonamide derivative for single photon emission computed tomography imaging targeting carbonic anhydrase-IX2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification and Evaluation of Bisquinoline Scaffold as a New Candidate for α-Synuclein-PET Imaging2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Synthesis and evaluation of novel technetium-99m-hydroxamamide complex based on imidazothiadiazole sulfonamide targeting carbonic anhydrase-IX for tumor imaging2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] αシヌクレインイメージングプローブの開発を目的とした新規18F標識スチリルキノリン/キノキサリン誘導体の合成と評価2021

Author(s)

Organizer

Data Source

[Presentation] カルコン類縁体を基盤としたαシヌクレイン標的PETイメージングプローブの開発2021

Author(s)

Organizer

Data Source

[Presentation] αシヌクレインイメージングプローブの開発を目的とした放射性ヨウ素標識オーロン誘導体の合成と評価2021

Author(s)

Organizer

Data Source

[Presentation] 神経変性疾患における脳タンパク質凝集体を標的とした核医学イメージング法の開発2021

Author(s)

Organizer

Data Source

[Presentation] αシヌクレインの生体イメージングを目的とした放射性ヨウ素標識スチリルキノキサリン誘導体の合成および評価2021

Author(s)

Organizer

Data Source

[Presentation] イミダゾチアジアゾールスルホンアミド骨格を導入した新規99mTc-ヒドロキサムアミド錯体の炭酸脱水酵素IXイメージングプローブとしての有用性評価2020

Author(s)

Organizer

Iikuni Shimpei 飯國慎平