MIYAZAKI Shunichi 宮崎俊一

… Alternative Names

MIYAZAKI Shun-ichi 宮崎俊一

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Researcher Number	80010081
Other IDs
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Affiliation (based on the past Project Information) *help	2009: 東京女子医科大学, 学長 1996 – 2006: 東京女子医科大学, 医学部, 教授 1998: 東京女子医大, 医学部, 教授 1993 – 1994: 東京女子医科大学, 医学部, 教授 1988 – 1991: 東京女子医科大学, 医学部, 教授 1986 – 1987: 自治医科大学, 医学部, 助教授
Review Section/Research Field	Principal Investigator General physiology / General physiology / Developmental biology Except Principal Investigator 動物発生・生理学 / General physiology / Developmental biology
Keywords	Principal Investigator 受精 / 哺乳動物卵 / 細胞内カルシウムイオン / カルシウムオシレーション / 精子因子 / 卵活性化 / 細胞内カルシウム / カルシウムイオン / カルシウム振動 / カルシウム波 … More / 細胞内情報伝達 / 卵活性化蛋白質 / 核移行 / ホスフォリパーゼCゼータ / Fertilization / 精子細胞質因子 / Ca^<2+> OSCILLATION / Ca^<2+> WAVE / FERTILIZATION / イノシトール3リン酸 / 精子 / 卵成熟 / イノシト-ル三リン酸 / GTP結合蛋白 / イノシト-ル3リン酸 / 細胞内カルシウムイオン遊離 / Nuclear transpotation abity / Phospholipase C-zeta / Egg-activating Protein / Cytosolic Sperm Factor / Calcium Oscillation / Mammalian Eggs / Intracellular Calcium Ion / 核移行能 / ホスホリパーゼCゼータ / nuclear translocation / phospholipase C zeta / sperm factor / calcium oscillation / intracellular calcium ion / egg activation / mammalian egg / fertilization / 卵細胞内精子注入法(ICSI) / CD9 / 精子一卵融合 / 前核 / Sperm Factor / Egg Activation / Ca^<2+> Oscillation / Intracellular Ca^<2+> / Mammalian Egg / 精子蛋白質 / Ca^<2+>オシレーション / 細胞内Ca^<2+>イオン / INTRACELLUAR Ca^<2+> / EGG ACTIVATION / SPERM / EGG / 卵活性化因子 / 哺乳動物精子 / 卵子 / SIGNAL TRANSDUCTION / ENDOPLASMIC RETICULUM / INOSITOL TRISPHOSPHATE RECEPTOR / INTRACELLULAR Ca^<2+> / MAMMALIAN EGG / カルシウム画像解析 / イノシトール4リン酸 / 細胞内信号伝達 / 小胞体 / イノシトール三リン酸受容体 / cytokine / oocyte maturation / inositol trisphosphate / intracellular calcium ion release / intracellular signaling / cell proliferation / イノシト-ルミリン酸 / Ca遊離機構 / 増殖刺激因子 / 細胞増殖 / プロティンキナーゼC / フォルボールエステル / 細胞内カルシウム測定 / パッチクランプ法 / カルシウムチャンネル / インターロイキン3 / 細胞増殖分化 / 未分化若幼血液細胞 / 単一細胞の解析 / イオンチャンネル / 増殖因子 / 血液細胞 / 細胞増殖・分化 / ミトコンドリア / Green Fluorescent Protein / Green fluorescent Protein / 可視化解析 / 遺伝子発現 / 哺乳類卵細胞 / 先体反応 / カルシウム / 単クロ-ン抗体 / イノシト-ル3リン酸受容体 / 細胞内カルシウム遊離 / カルシウムによるカルシウム遊離 / セロトニン / プロティンキナ-ゼC … More Except Principal Investigator 受精 / カルシウム / Neuron / Hamster egg / Medaka egg / Sea urchin egg / Amoeboid movement / Fertilization / Calcium ion / Fura2 / 原形質流動 / アメーバ運動 / エクオリン / カルシウムイオン / ニュ-ロン / ハムスタ-卵 / メダカ卵 / ウニ卵 / アメ-バ運動 / カルシウムイオン / 精子形成 / 遺伝子欠損マウス / カルシウムオシレーション / 卵活性化精子因子 / ホスホリパーゼCゼータ / 分子機構 / 進化 / 多様性 / プロテオミクス / 転写制御 / 血管平滑筋 / GFP / cAMP / 蛍光カルシウム指示薬 / 分泌 / 膵臓β細胞 / イノシトール三燐酸 Less

Functional analysis of phospholipase C-zeta-deficient mouse
- Principal Investigator
  
  ITO Masahiko
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
  Tokyo Women's Medical University
Characterization and functional analysis of phospholipase C-zeta, a candidate of mammalian egg-activating sperm factorPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Shunichi
- Project Period (FY)
  2004 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical University
受精機構の普遍性と進化:その分子基盤と次世代先端技術への戦略
- Principal Investigator
  
  岩尾康宏
- Project Period (FY)
  2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Developmental biology
- Research Institution
  Yamaguchi University
哺乳類卵子での遺伝子発現系の開発と応用Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical University
Identification of sperm-derived egg-activating protein at fertilization of mammalian eggsPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Shunichi
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical University
Identification of Ca^<2+>-oscillation-inducing Protein and Analysis of Its ActionPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Shunichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B).
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical University
細胞内情報伝達の生理機能解析と情報分子の可視化
- Principal Investigator
  
  飯野正光
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  The University of Tokyo
精子活性化の細胞内メカニズムの解明への直接的なアプローチPrincipal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Developmental biology
- Research Institution
  Tokyo Women's Medical University
Identification of sperm-derived egg-activating factor and analysis of molecular mechanisms of intracellular Ca^<2+> increase at fertilization of mammalian eggsPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Shunichi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical College
Physiological Study of the Mechanism Involved in Ca^<2+> Waves and Ca^<2+> Oscillations in Fertilized Mammalian EggsPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Shunichi
- Project Period (FY)
  1993 – 1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical College
哺乳動物卵に於ける細胞内Caイオン遊離機構の生理学的解析Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical University
哺乳動物卵受精における精子・卵結合の経膜的情報伝達機序Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Women's Medical University
哺乳動物卵受精における精子・卵結合の経膜的情報伝達機序Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1989
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Women's Medical University
Physiological Study of Intracellular Signaling for Induction of Cell ProliferationPrincipal Investigator
- Principal Investigator
  
  MIYAZAKI Shun-ichi
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical College
細胞増殖誘発とカルシウムチャンネルの活性化に関する研究Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Tokyo Women's Medical University
Developmental Physiological Research of Intracellular Dynamic Behaviors of Calcium Ion.
- Principal Investigator
  
  HIRAMOTO Yukio
- Project Period (FY)
  1988 – 1990
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  動物発生・生理学
- Research Institution
  The University of the Air
血液細胞の増殖・分化におけるカルシウムイオンの役割Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jichi Medical University
血液細胞の増殖・分化におけるイオンフラックスの役割Principal Investigator
- Principal Investigator
  
  宮崎俊一
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Jichi Medical University

All 2009 2008 2007 2006 2005 2004

All Journal Article Presentation

[Journal Article] Difference in Ca2+ oscillation - inducing activity and nuclear translocation ability of PLCZ1, an egg - activating sperm factor candidate, among mouse, rat, human and medaka fish.2008
- Author(s)
  Masahiko Ito, Tomohide Shikano, Shoji Oda, Takashi Horiguchi, Satomi Tanimoto, Takeo Awaji, Hiroshi Mitani, Shunichi Miyazaki.
- Journal Title
  
  Biol Reprod 78
  
  Pages: 1081-1090
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790170
[Journal Article] Relationship between Nuclear sequestration of PLCzeta and termination of PLCzeta-induced Ca2+ oscillations in mouse eggs.2008
- Author(s)
  Masahiko Ito, Tomohide Shikano, Keiji Kuroda, Shunichi Miyazaki.
- Journal Title
  
  Cell Calcium 44
  
  Pages: 400-410
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19790170
[Journal Article] Measuremenr of intracellular IP_3 during Ca^<2+> oscillations in mouse Eggs with GTP-based FRET probe2006
- Author(s)
  Shirakawa H, Ito M, Sato M, Umezawa Y, Miyazaki S
- Journal Title
  
  Biochemical and Biophysical Research Communications 345
  
  Pages: 781-788
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] The role of X/Y linker region and N-terminal EF-hand domain in nuclear translocation and Ca^<2+> oscillation-inducing activities of phospholipase Cζ, a mammalian egg-activating factor2006
- Author(s)
  Kuroda K, Ito M, Shikano T, Awaji T, Yoda A, Takeuchi H, Kinoshita K, Miyazaki S
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 27794-27805
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Measuremenr of intracellular IP, during CA^<2+> oscillations in mouse Eggs with GTP-based FRET probe2006
- Author(s)
  Shirakawa, H., Ito, M., Sato, M., Umezawa, Y., Miyazaki, S
- Journal Title
  
  Biochemical and BIophysical Research Communications 345
  
  Pages: 781-788
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] The role of X/Y linker region and N-terminal EF-hand domain in nuclear translocation and Ca^<2+> oscillation-inducing activities of phospholipase C a mammalian egg-activating factor2006
- Author(s)
  Kuroda, K., Ito, M., Shikano, T., Awaji, T., Yoda, A., Takeuchi, H., Kinoshita, K., Miyazaki, S.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 27794-27805
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Measuremenr of intracellular IP_3 during Ca^<2+> oscillations in mouse Eggs with GTP-based FRET probe2006
- Author(s)
  Shirakawa, H., Ito, M., Sato, M., Umezawa, Y., Miyazaki, S
- Journal Title
  
  Biochemical and Biophysical Research Communications 345
  
  Pages: 781-788
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] The role of X/Y linker region and N-terminal EF-hand domain in nuclear translocation and Ca^<2+> oscillation-inducing activities of phospholipase Cζ, a mammalian egg-activating factor2006
- Author(s)
  Kuroda, K., Ito, M., Shikano, T., Awaji, T., Yoda, A., Takeuchi, H., Kinoshita, K., Miyazaki.S.
- Journal Title
  
  Journal of Biological Chemistry 281
  
  Pages: 27794-27805
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] The role of EF-hand domains and C2 domain in regulation of enzymatic activity of phospholipase Cζ2005
- Author(s)
  Kouchi Z, Shikano T, Nakamura Y, Shirakawa H, Fukami K, Miyazaki S.
- Journal Title
  
  Journal of Biological Chemistry 280
  
  Pages: 21015-21021
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Nuclear translocation of phospholipase C-zeta, an egg-activating factor, during early embryonic development2005
- Author(s)
  Sone Y, Ito M, Shirakawa H, Shikano T, Takeuchi H, Kinoshita K, Miyazaki S.
- Journal Title
  
  Biochemical and Biophysical Research Communications 330
  
  Pages: 690-694
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] The role of EF-hand domains and C2 domain in regulation of enzymatic activity of phospholipase Cζ2005
- Author(s)
  Kouchi Z, Shikano T, Nakamura Y, Shirakawa H, Fukami K, Miyazaki S
- Journal Title
  
  Journal of Biological Chemistry 280
  
  Pages: 21015-21021
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Nuclear translocation of phospholipase C-zeta, an egg-activating factor, during early embryonic development2005
- Author(s)
  Sone Y, Ito M, Shirakawa H, Shikano T, Takeuchi H, Kinoshita K, Miyazaki S
- Journal Title
  
  Biochemical and Biophysical Research Communications 330
  
  Pages: 690-694
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Recombinant phospholipase C-zeta has high Ca^<2+> sensitivity and induces Ca^<2+> oscillations in mouse eggs2004
- Author(s)
  Kouchi Z, Fukami K, Shikano T, Oda S, Nakamura Y, Takenawa T, Miyazaki S
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 10408-10412
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Ca^<2+> oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation2004
- Author(s)
  Yoda A, Oda S, Shikano T, Kouchi Z, Awaji T, Shirakawa H, Kinoshita K, Miyazaki S
- Journal Title
  
  Developmental Biology 268
  
  Pages: 245-257
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Recombinant phospholipase C-zeta has high Ca^<2+> sensitivity and induces Ca^<2+> oscillations in mouse eggs2004
- Author(s)
  Kouchi Z, Fukami K, Shikano T, Oda S, Nakamura Y, Takenawa T, Miyazaki S.
- Journal Title
  
  Journal of Biological Chemistry 279
  
  Pages: 10408-10412
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Journal Article] Ca^<2+> oscillation-inducing phospholipase C zeta expressed in mouse eggs is accumulated to the pronucleus during egg activation2004
- Author(s)
  Yoda A, Oda S, Shikano T, Kouchi Z, Awaji T, Shirakawa H, Kinoshita K, Miyazaki S.
- Journal Title
  
  Developmental Biology 268
  
  Pages: 245-257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390055
[Presentation] Analysis of negative feedback mechanism of phospholipase C-zeta, a egg-activating sperm factor candidate, overexpression2009
- Author(s)
  伊藤昌彦、鹿野朝秀、村田智昭、宮崎俊一
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-19790170
[Presentation] 卵活性化精子因子候補ホスホリパーゼCゼータの核移行能の役割2007
- Author(s)
  伊藤昌彦、鹿野朝秀、堀口崇、谷本さとみ、三谷啓志、尾田正二、淡路健雄、宮崎俊一
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会
- Place of Presentation
  横浜
- Year and Date
  2007-12-09
- Data Source
  KAKENHI-PROJECT-19790170

1. SHIRAKAWA Hideki (40241070)

# of Collaborated Projects: 5 results

# of Collaborated Products: 9 results
2. AWAJI Takeo (60297546)

# of Collaborated Projects: 5 results

# of Collaborated Products: 5 results
3. ODA Shoji (50266714)

# of Collaborated Projects: 5 results

# of Collaborated Products: 7 results
4. KOHCHI Zen (70322485)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
5. ITO Masahiko (50385423)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
6. SHIRAISHI Koichi (50256476)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 須田年生 (60118453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. MIYADO Kenji (60324844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OSHIMI Kazuo (40089991)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MOHRI Tatsuma (60290912)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. HIRAMOTO Yukio (50011440)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. HAMAGUCHI Yukihisa (70016161)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. IWAMATSU Takashi (90023994)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. KUBOTA Hiroshi (40115837)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KURODA Kiyoko (30028138)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 飯野正光 (50133939)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 萩原正敏 (10208423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 河西春郎 (60224375)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岩尾康宏 (10144916)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 岡部勝 (30089875)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 星元紀 (20012411)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 深見泰夫 (00156746)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 佐藤英明 (80093243)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. 黒田英世 (50064845)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 中田健

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

MIYAZAKI Shunichi 宮崎 俊一

MIYAZAKI Shun-ichi 宮崎 俊一

Research Projects

Research Products

Co-Researchers

Functional analysis of phospholipase C-zeta-deficient mouse

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization and functional analysis of phospholipase C-zeta, a candidate of mammalian egg-activating sperm factorPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

受精機構の普遍性と進化:その分子基盤と次世代先端技術への戦略

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

哺乳類卵子での遺伝子発現系の開発と応用Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of sperm-derived egg-activating protein at fertilization of mammalian eggsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of Ca^<2+>-oscillation-inducing Protein and Analysis of Its ActionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

細胞内情報伝達の生理機能解析と情報分子の可視化

Principal Investigator

Project Period (FY)

Research Category

Research Institution

精子活性化の細胞内メカニズムの解明への直接的なアプローチPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Identification of sperm-derived egg-activating factor and analysis of molecular mechanisms of intracellular Ca^<2+> increase at fertilization of mammalian eggsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Physiological Study of the Mechanism Involved in Ca^<2+> Waves and Ca^<2+> Oscillations in Fertilized Mammalian EggsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

哺乳動物卵に於ける細胞内Caイオン遊離機構の生理学的解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

哺乳動物卵受精における精子・卵結合の経膜的情報伝達機序Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

哺乳動物卵受精における精子・卵結合の経膜的情報伝達機序Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Institution

MIYAZAKI Shunichi 宮崎俊一

MIYAZAKI Shun-ichi 宮崎俊一