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OZAWA Takayuki  小澤 高将

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… Alternative Names

小沢 高將  オザワ タカユキ

小沢 高将  オザワ タカユキ

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Researcher Number 80022771
External Links
Affiliation (based on the past Project Information) *help 1996: 名古屋大学, 名誉教授
1996: Nagoya University, Department of Biomedical Chemistry, Professor Emeritus, 医学部, 名誉教授
1986 – 1995: 名古屋大学, 医学部, 教授
1988: Prof of Biochemistry. Faculty of Medicine. Nagoya University, 医学部第二生化学, 教授
1987: 名古屋大学, 医学部・第二生化学, 教授
Review Section/Research Field
Principal Investigator
Pathological medical chemistry
Except Principal Investigator
General medical chemistry / Neurology / Pathological medical chemistry / 麻酔学 / Pediatrics / プラズマ理工学 / Circulatory organs internal medicine
Keywords
Principal Investigator
ミトコンドリアDNA / 電子伝達系酵素欠損 / 退行性病変 / 加齢現象 / 遺伝子変異 / ミトコンドリア脳筋症 / reactive oxygen species / aging / mitochondrial DNA / 8-hydroxydeoxyguanosine … More / 電子伝達系 / 活性酸素ラジカル / 欠失 / 電子伝達系酸素欠損 / 遺伝子欠失 / Ageing / Cardiomyopathy / Parkinson's disease / Mitochondrial encephalomyopathy / Point mutation / Gene deletion / Mitochondrial DNA / Electron-transfer chain / 活性酵素 / tRNA / degenerative diseases / deletion / mutation / mitochondrial myopathy / electron transfer defects / 慢性疲労症候群 / 加齡現象 / 活性酸素種 / deleted mtDNA / cardiomyopathy / oxidative stress / point mutations / ラジカル脆弱性 / 酸化的DNA損傷 / 老化 / ミトコンドリア病 / 心毒性 / 発癌物質 / 蛍光PCR-SSCP法 / 活性酸素 / 欠失mtDNA / 心筋症 / 酸化ストレス / 点変異 / 加齢 / サブユニット欠損 / 肥大型心筋症 / ミオパチー / オンコージ / ユビキノン / チトクロームcオキシダーゼ / 免疫電顕法 / 酸素欠損症 / プロトン輸送 / チトクロム / エネルギー転換 / ミトコンドア / フリーラジカル / カリウムチャネル / フォスファチジルイノシトール / Cキナーゼ / c-fos遺伝子 / 不整派 / 心筋 / 労作性ミオグロビン尿症 / チトクロムc酸化酵素 / 特発性心筋症 / レーバー氏病 / ピルビン酸脱水酵素遺伝子 / チトクロムc_1遺伝子 … More
Except Principal Investigator
ミトコンドリアDNA / バイオエナジェティックス / Mitochondrial DNA / 動脈硬化 / 遺伝子欠失 / ミトコンドリア遺伝子 / 肥大心 / 疾病 / 呼吸酵素系 / エネルギー / 8-Hydroxy-deoxyguanosine / ミトコンドリア / MELAS / ミトコンドリア脳筋症 / β受容体 / 心筋梗塞 / 内皮細胞 / 活性酸素障害 / ATP / ロイコトリエン / エネルギー産生系 / cytochrome c oxidase deficiency / Hypertrophic cardiomyopathy / Mitochondrial encephalomyopathy / Complex I subunit defect / Myopathy / Maternal Inheritance / Electron-transfer enzyme deficiency / サザンブロット法 / 複合体IV / 複合体I / 鉄-イオウクラスター / チトクロム / 遺伝子欠損 / 酵素欠損症 / ミオパチー複合体Iサブユニット欠損 / KearnsーSayre症候群 / チトクロムcオキシダーゼ欠損症 / 肥大型心筋症 / 複合体Iサブユニット欠損 / ミオパチー / 母系遺伝 / 電子伝達系酵素欠損症 / Tissue Po_2 / Leucotoxin / Neutrophils / Endotoxin shock / Dichloroacetate / Lysosome enzyme / 好中球 / ロイコトキシン(9.10ーエポキシー12ーオクタデセン酸) / ミトコンドリヤ膜 / 細胞内エネルギー / ライソゾーム酵素 / 組織酸素分圧 / 活性酵素 / ロイコトキシン / ミトコンドリヤ / エンドトキシン・ショック / 活性酸素 / ミトコンドリヤロイコトキシン / 酸化還元電位 / ライソゾーム / ショック / エンドトキシン / signal peptide / reactive oxygen species / cell death / oxidative damage / cell fusion / nucleotide substitutions / mitochondrial diseases / mitochondrial genome / 活性酸素ラジカル / 酸素ストレス / ρ^0細胞 / シグナルペプチド / 活性酸素種 / 細胞死 / 酸化的ストレス / 細胞融合 / 遺伝子変異 / ミトコンドリア病 / Muscle weakness / Aging / Oxygen damage / Deletion / 加齢に伴う筋力低下 / 8-hydroxydeoxyguanosine / 加齢現象 / 筋力低下 / エネルギ-産生 / 加齢 / エネルギー産生 / 遺伝子増幅 / 塩基配列決定 / 運動失調 / 脊髄小脳変性症 / Ageing / Energy production / Point mutation / Nucleotide sequencing / Ataxia / Mitochondria / Spinocerebellar degeneration / p0 cells / SV40 cell line / fibroblasts / oxidative phosphorylation / heteroplasmy / mitochondrial DNA / mitochondrial encephalomyopathy / 一塩基置換 / 相補作用 / 遺伝子ファミリ- / CPEO / ミトコンドリア点変異 / ミトコンドリアDNA欠失 / ρO細胞 / SV40クローン化細胞 / 培養線維芽細胞 / 電子伝達系酵素 / ヘテロプラスミー / 心筋エネルギー代謝 / ANP分泌 / イノシトール燐酸脂質 / α_1受容体 / 遺伝子 / 解離性大動脈瘤 / 細胞培養 / 血管平滑筋 / 冠状動脈攣縮 / 疾患動物モデル / ANS分泌 / ホスホリパーゼ活性 / ミオシンアイソザイム / phorbol ester / イノシトール燐脂質 / α受容体 / ATPase / バイノエナジェティックス / エネルギー転換 / 培養平滑筋細胞 / 肉皮細胞機能 / 心筋壊死 / 冠動脈攣縮 / 細胞増殖 / 解離性動脈瘤 / 細胞機能 / 細胞内Ca調節 / シグナルトランスダクター / セコンドメッセンヂャー / Ca / 脳卒中様発作 / 高乳酸血症 / NADH-ユビキノンリダクターゼ / チトクロム【-!c】.オキシダーゼ / ミトコンドリア・サイトパチー / サブユニット異常 / 酵素欠損証 / ミトコンドリア電子伝達系 / イオン濃度勾配 / 生体エネルギー転換 / 白血球 / 免疫 / 血行力学因子 / 血管病動物モデル / タン白キナーゼC / 脱感作 / 筋小胞体 / Caチャネル / セコンドメッセンジャー / 高次細胞機能 / Caイオン / アポトーシス / 組織酸素化 / 欠失 / 点変異 / 心筋症 / ミトコンドリア呼吸活性 / 心毒性 / PhIP / αβ複合体 / H^+輸送路 / 活性中心 / 高次構造 / 反応機構 / ATP合成酵素 / 心電シミュレーション / 心筋イオンチャンネル / 心筋異常電気活動 / 抗不整脈薬 / Ca^<2+>チャンネル / Na^+チャンネル / K^+チャンネル / 心筋 / 不整脈 / 脂肪酸構成 / 心筋脂肪酸摂取率 / 血中遊離脂肪酸 / 運動誘発心筋虚血 / PAF / ビタミンA / ビタミンD / ステロイド / トロンボキサン / プロスタグランジン / 生理活性脂質 / 生体エネルギ-転換 / 心房性ナトリウムペプチド / イノシト-ル燐脂質 / mRNA / プロテインキナ-ゼC / α1受容体 / 心筋負荷 / 進化 / ATPアーゼ Less
  • Research Projects

    (34 results)
  • Co-Researchers

    (73 People)
  •  心筋症に関与するミトコンドリア遺伝子変異の解明

    • Principal Investigator
      早川 美佳
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Nagoya University
  •  The role of reactive oxygen species and mitochondria in human neuromusclar diseases.

    • Principal Investigator
      YONEDA Makoto
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      University of Nagoya
  •  心筋細胞の代謝、分化異常に対する発癌物質の関与

    • Principal Investigator
      HAYAKAWA Mika
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  Mechanism of accumulation of mitochondrial DNA mutations associated with aging and diseasesPrincipal Investigator

    • Principal Investigator
      OZAWA Takayuki, 小沢 高将
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  心臓異常電気活動のサブセルラーメカニズムとその制御に関する研究

    • Principal Investigator
      平 則夫
    • Project Period (FY)
      1993
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Tohoku University
  •  心筋興奮・伝導の細胞内調節機構Principal Investigator

    • Principal Investigator
      小澤 高将
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  ATP合成酵素の高次構造

    • Principal Investigator
      二井 將光
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  Involvement of mitochondrial DNA mutations in aging and mitochondrial diseasesPrincipal Investigator

    • Principal Investigator
      OZAWA Takayuki
    • Project Period (FY)
      1992 – 1994
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya University
  •  Age-associated damage in mitochondrial DNA in human hearts

    • Principal Investigator
      HAYAKAWA M.
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      General medical chemistry
    • Research Institution
      Nagoya University
  •  ミトコンドリア遺伝子病における変異解析Principal Investigator

    • Principal Investigator
      小澤 高将 (小澤 高將)
    • Project Period (FY)
      1991 – 1993
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      Nagoya University
  •  Mutations of mitochondrial genome in spinocerebellar degeneration

    • Principal Investigator
      TANAKA Masashi
    • Project Period (FY)
      1991 – 1992
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Neurology
    • Research Institution
      Nagoya University
  •  バイオエナジェティックス

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  プロスタグランジンとその関連生理活性脂質の分子細胞学的作用機構

    • Principal Investigator
      山本 尚三
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      General medical chemistry
    • Research Institution
      The University of Tokushima
  •  心筋脂肪酸摂取率による心筋虚血の早期検出及び大きさの判定に関する研究

    • Principal Investigator
      横田 充弘
    • Project Period (FY)
      1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Circulatory organs internal medicine
    • Research Institution
      Nagoya University
  •  Studies on Pathogenesis of Mitochondrial Diseases

    • Principal Investigator
      TADA Keiya
    • Project Period (FY)
      1990 – 1992
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      TOHOKU UNIVERSITY
  •  酸化還元エネルギーPrincipal Investigator

    • Principal Investigator
      小澤 高将
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  バイオエナジェティックスの総括的研究

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  心筋細胞機能の調節・適応と破綻

    • Principal Investigator
      戸嶋 裕徳
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kurume University
  •  生体内血管系研究モデルの開発

    • Principal Investigator
      中村 元臣
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyushu University
  •  酸化還元エネルギーPrincipal Investigator

    • Principal Investigator
      小澤 高将
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  バイオエナジェティックスの総括的研究

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  心筋細胞機能の調節・適応と破綻

    • Principal Investigator
      戸嶋 裕徳
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kurume University
  •  Abnormality in Molecular Assembly of Electron-Transfer Complexes And ATP Synthase in Mitochondrial EncephalomyopathiesPrincipal Investigator

    • Principal Investigator
      OZAWA Takayuki, 小澤 高将
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for international Scientific Research
    • Research Institution
      University of Nagoya
  •  カルシウムイオンによる高次細胞機能の調節機構

    • Principal Investigator
      栗山 煕
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyushu University
  •  生体内血管系研究モデルの開発

    • Principal Investigator
      中村 元臣
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyushu University
  •  酸化還元エネルギーPrincipal Investigator

    • Principal Investigator
      小澤 高将
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Nagoya University
  •  バイオエナジェティックスの総括的研究

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Osaka University
  •  心筋細胞障害の成因と防御に関する基礎的研究

    • Principal Investigator
      戸嶋 裕徳
    • Project Period (FY)
      1987
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kurume University
  •  Pathophysiology of shock from cellular and metabolic aspects

    • Principal Investigator
      OKADA Kazuo
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      麻酔学
    • Research Institution
      Teikyo University
  •  Gene expression and its abnormality in mitochondrial electron-transfer enzyme deficiency.

    • Principal Investigator
      TANAKA Masashi
    • Project Period (FY)
      1987 – 1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Faculty of Medicine, University of Nagoya
  •  カルシウムイオンによる高次細胞機能の調節機構

    • Principal Investigator
      栗山 煕
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyushu University
  •  生体内血管系研究モデルの開発

    • Principal Investigator
      中村 元臣
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Special Project Research
    • Research Institution
      Kyushu University
  •  バイオエナジェティックス

    • Principal Investigator
      向畑 恭男
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      プラズマ理工学
    • Research Institution
      Osaka University
  •  ミトコンドリア電子伝達系酵素欠損の分子的機作の解明

    • Principal Investigator
      田中 雅嗣
    • Project Period (FY)
      1986
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pathological medical chemistry
    • Research Institution
      Nagoya University
  • 1.  TANAKA Masashi (60155166)
    # of Collaborated Projects: 8 results
    # of Collaborated Products: 0 results
  • 2.  KAGAWA Yasuo (30048962)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 3.  二井 將光 (50012646)
    # of Collaborated Projects: 6 results
    # of Collaborated Products: 0 results
  • 4.  HAYAKAWA Mika (10238090)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 5.  安楽 泰宏 (20012643)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 6.  向畑 恭男 (10028110)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 0 results
  • 7.  TADA Keiya (20046907)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 8.  松原 央 (00028242)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 9.  佐藤 猛 (40018594)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 10.  折井 豊 (60028149)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 11.  戸嶋 裕徳 (00080664)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 12.  矢崎 義雄 (20101090)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 13.  河村 慧四郎 (00026832)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 14.  滝島 任 (20004765)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 15.  福崎 恒 (90030824)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 16.  平 則夫 (60004553)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 17.  中村 元臣 (60037322)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 18.  家森 幸男 (80025600)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 19.  井上 通敏 (30028401)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 20.  京極 方久 (70025542)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 21.  中尾 真 (10013781)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 22.  NISHIKIMI Morimitsu (20022816)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 23.  小池 正彦 (10039521)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 24.  栗山 煕 (40037495)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 25.  吉田 博 (70028273)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 26.  神谷 瞭 (50014072)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 27.  NAGLEY Phillip
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 28.  LINNANE W.An
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 29.  LINNANE Anthony w.
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 30.  MIYABAHASHI Shigeaki (20174203)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 31.  WADA Yoshiroh (30004849)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 32.  SAHASHI Ko (90131242)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 33.  YONEDA Makoto (70270551)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 34.  OKADA Kazuo (30082093)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 35.  MIYAKE Tamotsu (90074476)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 36.  YOSHITAKE Junichi (10041386)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 37.  YOSHIMURA Nozomu (60041399)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 38.  福井 俊郎 (90029843)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
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  • 40.  岡本 光弘 (90028613)
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  • 41.  市川 厚 (10025695)
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  • 48.  外山 淳治 (20023658)
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  • 49.  橋本 敬太郎 (10004665)
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  • 50.  有田 真 (60037364)
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  • 52.  堅田 利明 (10088859)
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  • 53.  今井 昭一 (60013869)
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  • 54.  飯島 俊彦 (30004724)
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  • 55.  中谷 晴昭 (60113594)
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  • 56.  遠藤 政夫 (40004668)
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  • 58.  白木原 康雄 (20150287)
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  • 59.  伊藤 雄而 (10013517)
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  • 60.  田川 邦夫 (40028296)
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  • 61.  茂木 立志 (90219965)
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  • 62.  川崎 敏祐 (50025706)
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  • 63.  清水 孝雄 (80127092)
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  • 72.  リネン アンソニー・W.
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  • 73.  MARZUKI Sangkot
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