YAMADA Hidenori 山田秀徳

Researcher Number	80037613
Other IDs
Affiliation (based on the past Project Information) *help	2005 – 2011: 岡山大学, 大学院・自然科学研究科, 教授 2006: OKYAMA UNIVERSITY, Graduate school of natural science and technology, professor, 大学院自然科学研究科, 教授 2006: Okayama University, Graduate School of Natural Science and Technology, Professor, 自然科学研究科, 教授 2004: Okayama Univ., Faclt.Engineering, Professor, 工学部・生物機能工学科, 教授 1994 – 2004: 岡山大学, 工学部, 教授 1986 – 1990: 九州大学, 薬学部, 助手
Review Section/Research Field	Principal Investigator Biofunction/Bioprocess / 生物・生体工学 / 有機工業化学 / Biological pharmacy / 物質生物化学 / Biomedical engineering/Biological material science Except Principal Investigator Biomedical engineering/Biological material science / 生物・生体工学 / 物性一般(含基礎論)
Keywords	Principal Investigator フォルディング / 化学修飾 / タンパク質工学 / バイオテクノロジー / 増殖阻害 / protein engineering / 遺伝子工学 / 細胞内導入 / タンパク質 / 蛋白質 … More / 生物・生体工学 / リボヌクレアーゼ / 細胞毒性 / RNase / 成長因子 / biotechnology / cell culture / protein purfication / folding / protein transduction / chemical modification / Protein / 培養細胞 / 分離・精製 / Growth inhibition / Growth factor / Anti-cancer agent / 細胞増殖阻害 / 細胞成長因子 / 制ガン剤 / inclusion body / solubility of denatured protein / thiol-protecting reagent / 可逆的チオール修飾試薬 / 変性タンパク質の可溶化 / インクルージョンボディ / 変性タンパク質の溶解度 / チオール保護試薬 / Renaturation / Deaminated / Processing of N-terminal methionine / Eschericia coli / Chicken lysozyme / Gene engineering / 変異リゾチ-ム / SS-SH交換反応 / 巻戻し / デアミデ-ション / N末端プロセッシング / 大腸菌 / ニワトリリゾチ-ム / ニワトリリゾチーム / 巻き戻し / ケミカルバイオロジー / 細胞・組織 / 細胞内イメージング / バィオテクナロジー / フオルデイング / 格子工学 / 可溶化 / 結晶化 / RNase活性 / ハイブリッド蛋白質 / ポリエチレンイミン / 蛋白質のカチオン化 / エンドサイトーシス / 標的 / ダイマー化 / アミド化 / 正電荷 / Rnase / ハイブリット蛋白質 / 標的細胞 … More Except Principal Investigator 蛋白質工学 / ドラッグデリバリーシステム / Drug delivery system / タンパク質工学 / リゾチーム遺伝子の発現 / 変異リゾチーム / ニワトリリゾチーム / エンベロープ蛋白質 / 膜蛋白質 / Envelope protein / Protein engineering / Liposome / Protein assembly / Virus / Biotechnology / Nano-Bio / タンパク質集合体 / エンベロープタンパク質 / ウィルス粒子 / ナノ粒子 / リポソーム / 蛋白質集合体 / ウィルス / 生物・生体 / ナノバイオ / Protein Engineering / anti-cancer drug / Artificial virus / Molecular targetting / 制癌剤 / 人工ウィルス / 分子標的 / CRIPTO / FIBROBLAST GROWTH FACTOR / SOLUBLE RECEPTOR / EXOCYTOSIS / GROWTH FACTOR / SECRETION SIGNAL / 融合タンパク質 / グリーンフルオレッセントプロテイン / クリプト / 塩基性線維芽細胞増殖因子 / 可溶性受容体 / 細胞外輸送 / 増殖因子 / 分泌シグナル / 変性蛋白質の再生 / サイトディレクティッドムタジェネシス / 変性タンパク質の再生 / サイトディレクテッドムタジェネシス / ワクチン / 薬物送達システム / 大腸菌発現系 / B型肝炎ウィルス / 擬似ウィルス粒子 / 蛋白質構造 / ウィルスエンベロープ / ナノ・バイオ / ウィルスエンベロープ蛋白質 / バイオナノ粒子 / 構造変調 / 構造相転移 / 比熱 / 動的立体構造特性 / 協同的分子運動 / 生体高分子 / ACカロリーメーター / 比熱測定 / バイオリアクター / コウジ酸 / 膜面液体培養 / Aspergillus oryzae / 糸状菌 Less

Rapid and large scale production system of virus-like hollow nano-particles using Escherichia Coli
- Principal Investigator
  
  TADA Hiroko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Okayama University
変性タンパク質の可溶化技術を活用した細胞内イメージング技術の開発Principal Investigator
- Principal Investigator
  
  山田秀徳
- Project Period (FY)
  2008 – 2009
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Okayama University
Development of analytical and production method for problematic protein by artificial control of physical property of proteinPrincipal Investigator
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  2007 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  Okayama University
Surface structure analysis of hollow nano-particle formed by HBsAg proteins with deletion of major antigenic region
- Principal Investigator
  
  TADA Hiroko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Okayama University
Development and application of in cell folding technology based on reversible cationization of denatured proteins.Principal Investigator
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biofunction/Bioprocess
- Research Institution
  OKYAMA UNIVERSITY
Molecular mechanisms of hollow nano-particle formation by a viral envelope protein
- Principal Investigator
  
  TADA Hiroko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  OKAYAMA UNIVERSITY
Target cell specific delivery system of anti-cancer drugs by Bio-nano particles.
- Principal Investigator
  
  TADA Hiroko
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  OKAYAMA UNIVERSITY
ACカロリメーター比熱測定による生体高分子の協同的立体構造変調の研究
- Principal Investigator
  
  日高昌則
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  物性一般(含基礎論)
- Research Institution
  Kyushu University
蛋白質のハイブリッド化による成長因子受容体を標的とする細胞増殖阻害分子の構築Principal Investigator
- Principal Investigator
  
  山田秀徳
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
蛋白質のハイブリッド化による成長因子受容体を標的とする細胞増殖阻害分子の構築Principal Investigator
- Principal Investigator
  
  山田秀徳
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
蛋白質のハイブリッド化による成長因子受容体を標的とする細胞増殖阻害分子の構築Principal Investigator
- Principal Investigator
  
  山田秀徳
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Okayama University
Development of anti-cancer reagent utilizing cytotoxic potential of human ribonucleasesPrincipal Investigator
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  生物・生体工学
- Research Institution
  Okayama University
ANALYSES OF EXOCYTOSIS SPECIFIC TO GROWTH FACTORS THAT HAVE NO SECRETION SIGNALS
- Principal Investigator
  
  SENO Masaharu
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  生物・生体工学
- Research Institution
  OKAYAMA UNIVERSITY
カビの潜在機能を活用する新規な培養システムの開発
- Principal Investigator
  
  中西一弘
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  生物・生体工学
- Research Institution
  Okayama University
Preparation and application to protein engineering of thiol-protecting reagent having charges.Principal Investigator
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  有機工業化学
- Research Institution
  Okayama University
Study on the Renaturation of Mutant Lysozymes Expressed in Schericia Coli.Principal Investigator
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
化学修飾および遺伝子工学による蛋白質のフォルディング過程の解析Principal Investigator
- Principal Investigator
  
  山田秀徳
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
遺伝子工学によるリゾチームの酵素機能の徹底的解明と機能変換
- Principal Investigator
  
  堀内忠郎
- Project Period (FY)
  1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University
遺伝子工学によるリゾチームの酵素機能の徹底的解明と機能変換
- Principal Investigator
  
  堀内忠郎
- Project Period (FY)
  1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyushu University

All 2011 2010 2009 2008 2007 2006 2005 2004 2003

All Journal Article Presentation Patent

[Journal Article] Polyethylenimine-cationized-catenin protein transduction activates the Wnt canonical signaling pathway more effectively than cationic lipid-based transduction2010
- Author(s)
  Midori Kitazoe, Junichiro Futami, Mitsuo Nishikawa, Hidenori Yamada, Yoshitake Maeda.
- Journal Title
  
  Biotechnology Journal 5
  
  Pages: 385-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Polyethylenimine-cationized-catenin protein transduction activates the Wnt canonical signaling pathway more effectively than cationic lipid-based transduction2010
- Author(s)
  Midori Kitazoe, Junichiro Futami, Mitsuo Nishikawa, Hidenori Yamada, Yoshitake Maeda
- Journal Title
  
  Biotechnology Journal 5
  
  Pages: 385-392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Polyethylenimine-cationized beta-catenin protein transduction activates the Wnt canonical signaling pathway more effectively than cationic lipid-based transduction2010
- Author(s)
  Hidenori Yamada(4番目、他4名)
- Journal Title
  
  Biotechnol. J
  
  Volume: vol.5, No.4 Pages: 14-20
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500426
[Journal Article] Polyethylenimine-cationized beta-catenin protein transduction activates the Wnt canonical signaling pathway more effectively than cationic lipid-based transduction2010
- Author(s)
  Midori Kitazoe, Hidenori Yamada, et.al.
- Journal Title
  
  Biotechnol.J.
  
  Volume: 5(4) Pages: 385392-385392
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21500426
[Journal Article] Transient cell proliferation with polyethylenimine-cationized N-terminal domain of Simian Virus 40 large T-antigen2008
- Author(s)
  Murata H., Futami J., Kitazoe M., Kosaka M., Tada H., Seno M., Yamada H.
- Journal Title
  
  J.Biosci.Bioeng 105
  
  Pages: 34-38
- NAID
  110006570773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Transient cell proliferation with polyethylenimine-cationized N-terminal domain of Simian Virus 40 large T-antigen.2008
- Author(s)
  Murata H., Futami J., Kitazoe M., Kosaka M., Tada H., Seno M., Yamada H.
- Journal Title
  
  J.Biosci.Bioeng. 105
  
  Pages: 34-38
- NAID
  110006570773
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Intracellular delivery of glutathione S-transferase-fused proteins into mammalian cells by polyethylenimine-glutathione conjugates.2008
- Author(s)
  Hitoshi Muratal, Junichiro Futami, Midori Kitazoe, Takayuki Yonehara, Hidetaka Nakanishi, Megumi Kosaka, Hiroko Tada, Masakiyo Sakaguchi, Yasuyuki Yagi, Masaharu Seno, Nam-ho Huh, Hidenori Yamada.
- Journal Title
  
  Journal of Biochemistry 144(4)
  
  Pages: 447-455
- NAID
  10024912690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Design of cytotoxic ribonucleases by cationization to enhance intracellular protein delivery2008
- Author(s)
  Junichiro Futami, Hidenori Yamada
- Journal Title
  
  Cur.Pharm.Biotechnol 9
  
  Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Design of cytotoxic ribonucleases by cationization to enhance intracellularprotein delivery.2008
- Author(s)
  Futami J., Yamada H.
- Journal Title
  
  Cur. Pharm. Biotechnol. 9
  
  Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Design of cytotoxic ribonucleases by cationization to enhance intracellular protein delivery.2008
- Author(s)
  Junichiro Futami, Hidenori Yamada.
- Journal Title
  
  Cur.Pharm.Biotechnol. 9
  
  Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Design of cytotoxic ribonucleases by cationization to enhance intracellular protein delivery.2008
- Author(s)
  Futami J., Yamada H.
- Journal Title
  
  Cur. Pharm. Biotechnol. 9
  
  Pages: 180-184
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20650070
[Journal Article] Intracellular delivery of glutathione S-transferase-fused proteins into mammalian cells by polyethylenimine-glutathione conjugates2008
- Author(s)
  Hitoshi Murata, Junichiro Futami, Midori Kitazoe, Takayuki Yonehara, Hidetaka Nakanishi, Megumi Kosaka, Hiroko Tada, Masakiyo Sakaguchi, Yasuyuki Yagi, Masaharu Seno, Nam-ho Huh, Hidenori Yamada
- Journal Title
  
  Journal of Biochemistry 144(4)
  
  Pages: 447-455
- NAID
  10024912690
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Exploiting protein cationization in future drug development.2007
- Author(s)
  Futami J., Kitazoe M., Murata H., Yamada H.
- Journal Title
  
  Expert Opinion on Drug Discovery 2
  
  Pages: 261-269
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360399
[Journal Article] 'Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry : crystallization and structure determination of a mutant human RNase 1 with a hydrophobic interface of leucines.2007
- Author(s)
  Yamada H., Tamada T., Kosaka M., Miyata K., Fujiki S., Tano M., Moriya M., Yamanishi M., Honjo E., Tada H., Ino T., Yamaguchi H., Futami J., Seno M., Nomoto T., Hirata T., Yoshimura M., Kuroki R.
- Journal Title
  
  Protein Sci. 16
  
  Pages: 1389-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Characterization of bio-nanocapsule as a transfer vector targeting human hepatocyte carcinoma by disulfide linkage modification2007
- Author(s)
  Nagaoka T, Fukuda T, Yoshida S, Nishimura H, Yu D, Kuroda S, Tanizawa K, Kondo A, Ueda M, Yamada H, Tada H, Seno M
- Journal Title
  
  J Controled Release 118(3)
  
  Pages: 348-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19500405
[Journal Article] Crystal lattice engineering,' an approach to engineer protein crystal contacts by creating intermolecular symmetry: crystallization and structure determination of a mutant human RNase I with a hydrophobic interface of leucines.2007
- Author(s)
  Yamada, H., et. al.
- Journal Title
  
  Protein Sci. 16(7)
  
  Pages: 1389-1397
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19206085
[Journal Article] Denatured and reversibly cationized p53 readily enters cells and simultaneously folds to the functional protein in the cells.2006
- Author(s)
  Murata H., Sakaguchi M., Futami J., Kitazoe M., Maeda T., Doura H., Kosaka M.Tada H., Seno M., Huh N.H., Yamada H.
- Journal Title
  
  Biochemistry 45
  
  Pages: 6124-6132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360399
[Journal Article] Targeted disruption of transcriptional regulatory function of p53 by a novel efficient method for introducing a decoy oligonucleotide into nuclei.2005
- Author(s)
  Sakaguchi M., Nukui T., Sonegawa H., Murata H., Futami J., Yamada H., Huh N, H.
- Journal Title
  
  Nucleic Acids Res. 33
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360399
[Journal Article] Intracellular delivery of proteins into mammalian living cells by polyethylenimine-cationization.2005
- Author(s)
  Futami J., Kitazoe M., Maeda T., Nukui E., Sakaguchi M., Kosaka J., Miyazaki M., Kosaka M., Tada H., Seno M., Sasaki J., Huh N.-H., Namba M., Yamada H.
- Journal Title
  
  J. Biosci. Bioeng. 99
  
  Pages: 95-103
- NAID
  110002695633
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360399
[Journal Article] Protein transduction assisted by polyethylenimine-cationized carrier proteins.2005
- Author(s)
  Kitazoe M., Murata H., Futami J., Maeda T., Sakaguchi M., Miyazaki M., Kosaka M., Tada H., Seno M., Huh N.H., Namba M., Nishikawa M., Maeda Y., Yamada H.
- Journal Title
  
  J. Biochem. (Tokyo) 137
  
  Pages: 693-701
- NAID
  10017345558
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17360399
[Journal Article] Novel tissue and cell type-specific gene/drug delivery system using surface engineered hepatitis B virus nano-particles.2004
- Author(s)
  Tadanori Yamada et al.
- Journal Title
  
  Curr Drug Targets Infect Disord 4(2)
  
  Pages: 163-167
- Data Source
  KAKENHI-PROJECT-15500317
[Journal Article] Novel tissue and cell type-specific gene/drug delivery system using surface engineered hepatitis B virus nano-particles.2004
- Author(s)
  Tadanori Yamada
- Journal Title
  
  Curr Drug Targets Infect Disord 4(2)
  
  Pages: 163-167
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500317
[Journal Article] 中空バイオナノ粒子を用いたピンポイントドラッグデリバリーシステム2004
- Author(s)
  山田忠範
- Journal Title
  
  高分子論文集 61(12)
  
  Pages: 606-612
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500317
[Journal Article] Nanoparticles for the delivery of genes and drugs to human hepatocytes.2003
- Author(s)
  Yamada Tadanori
- Journal Title
  
  Nature biotechnology 21(8)
  
  Pages: 885-890
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15500317
[Journal Article] Nanoparticles for the delivery of genes and drugs to human hepatocytes.2003
- Author(s)
  Tadanori Yamada
- Journal Title
  
  Nature biotechnology 21(8)
  
  Pages: 885-890
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15500317
[Patent] チオスルホナート化合物、タンパク質及び/又はペプチドの可逆的カチオン化剤並びに可溶化方法2011
- Inventor(s)
  二見淳一郎、山田秀徳、久良木豪、矢木恵一郎
- Industrial Property Rights Holder
  岡山大学
- Filing Date
  2011-03-24
- Overseas
- Data Source
  KAKENHI-PROJECT-19206085
[Patent] チオスルホナート化合物、タンパク質及び/又はペプチドの可逆的カチオン化剤並びに可溶化方法2010
- Inventor(s)
  二見淳一郎、山田秀徳、久良木豪、矢木恵一郎
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2010-070804
- Filing Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-20650070
[Patent] チオスルホナート化合物、タンパク質及び/又はペプチドの可逆的カチオン化剤並びに可溶化方法2010
- Inventor(s)
  二見淳一郎、山田秀徳、久良木豪、矢木恵一郎
- Industrial Property Rights Holder
  岡山大学
- Industrial Property Number
  2010-070804
- Filing Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-19206085
[Patent] チオスルホナート化合物、タンパク質及び/又はペプチドの可逆的カチオン化剤並びに可溶化方法2010
- Inventor(s)
  二見淳一郎, 山田秀徳, 久良木豪, 矢木恵一郎
- Industrial Property Rights Holder
  岡山大学
- Filing Date
  2010-03-25
- Data Source
  KAKENHI-PROJECT-19206085
[Patent] 低抗原性のHBsAg粒子およびその作製法2006
- Inventor(s)
  山田一朗, 妹尾昌治, 多田宏子
- Industrial Property Rights Holder
  岡山大学(株)ビークル
- Industrial Property Number
  2006-220346
- Filing Date
  2006-08-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17500306
[Presentation] タンパク質可逆的修飾試薬を活用したがん免疫への応用2010
- Author(s)
  藤原健剛, 矢木恵一郎, 二見淳一郎, 山田秀徳
- Organizer
  第33回日本分子生物学会年会
- Year and Date
  2010-12-07
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 変性タンパク質の可溶化技術と工学的応用2010
- Author(s)
  二見淳一郎、矢木恵一郎、藤原健剛、山田秀徳
- Organizer
  第9回日本蛋白質科学会年会
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 変性タンパク質の可溶化技術と工学的応用2010
- Author(s)
  二見淳一郎, 山田秀徳
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  札幌
- Year and Date
  2010-06-18
- Data Source
  KAKENHI-PROJECT-21500426
[Presentation] タンパク質カチオン化技術を活用した細胞機能制御2010
- Author(s)
  二見淳一郎, 藤原健剛, 矢木恵一郎, 村田等, 山田秀徳
- Organizer
  第83回日本組織培養学会
- Year and Date
  2010-05-20
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 可逆的変性カチオン化法を用いた細胞内導入型転写因子の開発2009
- Author(s)
  二見淳一郎, 浅間孝志, 山田秀徳
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本全日空ホテルニュースカイ(熊本県)
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] ヒトD型肝炎ウィルス形成メカニズムを利用したHBsAg粒子内部への機能蛋白質封入法2009
- Author(s)
  栗木政徳、小坂恵、二見淳一郎、山田秀徳、妹尾昌治、多田宏子*
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本全日空ホテルニュースカイ(熊本市)
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-21500426
[Presentation] 細胞内総タンパク質の可逆的変性カチオン化と溶解性に関する研究2009
- Author(s)
  久良木豪, 藤原健剛, 矢木恵一郎, 二見淳一郎, 山田秀徳
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-12-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 可逆的変性カチオン化法を用いた細胞内導入型転写因子の開発2009
- Author(s)
  二見淳一郎, 浅間孝志, 山田秀徳
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2009-05-20
- Data Source
  KAKENHI-PROJECT-20650070
[Presentation] 可逆的タンパク質マンノース化試薬の合成と評価2009
- Author(s)
  藤原健剛, 久良木豪, 二見淳一郎, 山田秀徳
- Organizer
  第32回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Year and Date
  2009-12-11
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 可逆的カチオン化による細胞から抽出しか変性状態の総タンパク質の可溶化2008
- Author(s)
  久良木豪, 二見淳一郎, 山田秀徳
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-20650070
[Presentation] B 型肝炎ウィルスエンベロープ蛋白質によるウィルス様粒子形成にTM1ヘリックスは不必要である2008
- Author(s)
  遠部圭佑, 多田宏子, 栗木政徳, 小坂恵, 二見淳一郎, 妹尾昌治, 山田秀徳
- Organizer
  第8回蛋白質科学会年会
- Place of Presentation
  東京
- Year and Date
  2008-06-10
- Data Source
  KAKENHI-PROJECT-19500405
[Presentation] 変性タンパク質の可溶化と細胞内導入を目的とした新規SH基多価カチオン化試薬の合成と解析2008
- Author(s)
  穴井祐介, 矢木恵一郎, 二見淳一郎, 小坂恵, 多田宏子, 山田秀徳
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] (*原研) 結晶格子工学によるウシRNase Aの結晶空間群の変更2008
- Author(s)
  土井慎一, 小坂恵, 二見淳一郎, 多田宏子, 玉田太郎, 岡崎伸生, 黒木良太, 山田秀徳
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 (BMB2008)
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 中空ナノ粒子形成に対するHBVエンベロープ蛋白質粒子内部領域の影響。2008
- Author(s)
  栗木政徳、多田宏子、遠部圭佑、小坂恵、二見淳一郎、妹尾昌治、山田秀徳
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Place of Presentation
  神戸
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19500405
[Presentation] 可逆的カチオン化による細胞から抽出した変性状態の総タンパク質の可溶化2008
- Author(s)
  久良木豪, 二見淳一郎, 山田秀徳
- Organizer
  第8回日本蛋白質科学会年会
- Place of Presentation
  東京
- Year and Date
  2008-06-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 結晶格子工学によるウシRNase Aの結晶空間群の変更2008
- Author(s)
  土井慎一, 小坂恵, 二見淳一郎, 多田宏子, 玉田太郎, 岡崎伸生, 黒木良太, 山田秀徳
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会(BMB2008)
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 変性タンパク質の可溶化と細胞内導入を目的とした新規SH基多価カチオン化試薬の合成と解析2008
- Author(s)
  穴井祐介, 矢木恵一郎, 二見淳一郎, 小坂恵, 多田宏子, 山田秀徳
- Organizer
  第31回日本分子生物学会年会・第81回日本生化学会大会合同大会 (BMB2008)
- Year and Date
  2008-12-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] カチオン化アビジンによるビオチン化タンパク質細胞内導入における導入効率の解析と評価2007
- Author(s)
  二見翠、二見淳一郎、渡邉泰宜、村田等、多田宏子、妹尾昌治、山田秀徳
- Organizer
  2007年日本化学会西日本大会
- Year and Date
  2007-11-11
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 人工転写因子を用いたタンパク質細胞内導入効率の定量化2007
- Author(s)
  二見淳一郎、浅間孝志、北添翠、村田等、小坂恵、多田宏子、妹尾昌治、山田秀徳
- Organizer
  第30回日本分子生物学会年会・第80回日本生化学会大会合同大会(BMB2007)
- Year and Date
  2007-12-12
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] 粒子形成に必要なヒトB型肝炎ウィルスエンベロープ蛋白質配列の特定2007
- Author(s)
  多田宏子, 宮崎望美, 下光翔子, 山田一朗, 栗木政徳, 二反田有沙, 近藤昭彦, 谷澤克行, 黒田俊一, 上田政和, 小坂恵, 二見淳一郎, 山田秀徳, 妹尾昌治
- Organizer
  第7回日本蛋白質科学会年会
- Place of Presentation
  仙台
- Year and Date
  2007-05-26
- Data Source
  KAKENHI-PROJECT-19500405
[Presentation] ポリエチレンイミン(PEI)グルタチオンキャリアーを用いたGST-融合タンパク質の細胞導入2007
- Author(s)
  村田等、二見淳一郎、北添翠、小坂恵、多田宏子、甲斐敬、妹尾昌治、山田秀徳
- Organizer
  第59回日本生物工学会大会
- Year and Date
  2007-09-26
- Data Source
  KAKENHI-PROJECT-19206085
[Presentation] ヒトD型肝炎ウィルス形成メカニズムを利用したHBsAg粒子内部への機能蛋白質封入法2006
- Author(s)
  栗木政徳、小坂恵、二見淳一郎、山田秀徳、妹尾昌治、多田宏子
- Organizer
  第9回日本蛋白質科学会年会
- Place of Presentation
  熊本
- Year and Date
  2006-05-20
- Data Source
  KAKENHI-PROJECT-21500426

1. SENOO Masaharu (90243493)

# of Collaborated Projects: 9 results

# of Collaborated Products: 15 results
2. TADA Hiroko (60271061)

# of Collaborated Projects: 9 results

# of Collaborated Products: 25 results
3. FUTAMI Jyunichirou (00420498)

# of Collaborated Projects: 3 results

# of Collaborated Products: 32 results
4. KOSAKA Megumi (00170233)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
5. IMOTO Taiji (90038282)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 堀内忠郎 (10037567)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. 三木健良 (40037586)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. KURODA Shun' ichi (60263406)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. UEDA Tadashi (90184928)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 中西一弘 (90026584)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 崎山高明 (70170628)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 日高昌則 (50037298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 杉山正明 (10253395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 前田米蔵 (30037262)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 渡邊啓一 (40191754)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMADA Hidenori 山田 秀徳

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変性タンパク質の可溶化技術を活用した細胞内イメージング技術の開発Principal Investigator

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Development of analytical and production method for problematic protein by artificial control of physical property of proteinPrincipal Investigator

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Development and application of in cell folding technology based on reversible cationization of denatured proteins.Principal Investigator

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蛋白質のハイブリッド化による成長因子受容体を標的とする細胞増殖阻害分子の構築Principal Investigator

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蛋白質のハイブリッド化による成長因子受容体を標的とする細胞増殖阻害分子の構築Principal Investigator

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蛋白質のハイブリッド化による成長因子受容体を標的とする細胞増殖阻害分子の構築Principal Investigator

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Development of anti-cancer reagent utilizing cytotoxic potential of human ribonucleasesPrincipal Investigator

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Preparation and application to protein engineering of thiol-protecting reagent having charges.Principal Investigator

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YAMADA Hidenori 山田秀徳