IMOTO Taiji 井本泰治

Researcher Number	90038282
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Affiliation (based on the past Project Information) *help	2009: Sojo University, 生物生命学部, 教授 2003: Sojo University, Faculty of Engineering, Professor, 工学部, 教授 2002: 九州大学, 大学院・薬学研究院, 教授 2001: Kyushu Univ., Grad. School Pharm. Sci., Prof., 薬学研究院, 教授 2000: 九州大学, 大学院・薬学研究院, 教授 … More
Review Section/Research Field	Principal Investigator Biological pharmacy / Applied biochemistry / 物質生物化学 Except Principal Investigator 物質生物化学 / Biological pharmacy / Physical pharmacy / Biological Sciences / 応用微生物学・応用生物化学 / 病態科学系歯学(含放射線系歯学) / Biophysics / Structural biochemistry / Chemical pharmacy
Keywords	Principal Investigator リゾチーム / フォルディング / ランダムライブラリー / タンパク質 / NMR / cDNA / 変異タンパク質 / 構造形成機構 / 再生反応 / 巻き戻し … More Except Principal Investigator NMR / リゾチーム / フォルディング / 遺伝子工学 / 大腸菌 / lysozyme / order parameter / ^<15>N labeling / 緩和解析 / Pichia pastoris / 核磁気共鳴 / 加水分解酵素 / 機能発現機構 / 基質特異性 / アクロモバクタープロテアーゼI / リボヌクレアーゼ / ホスホリパーゼA_2 / 非ペプシン型プロテアーゼ / 立体構造の相同性 / β-アミロイドペプチド / 凝集反応 / ニワトリリゾチーム / 化学修飾 / ニワトリリゾチ-ム / N末端プロセッシング / デアミデ-ション / 巻戻し / SS-SH交換反応 / 変異リゾチ-ム / Gene engineering / Chicken lysozyme / Eschericia coli / Processing of N-terminal methionine / Deaminated / Renaturation / 溶菌酵素 / 遺伝子組み換え / 耐病性 / 薬用植物 / リゾチーム遺伝子 / 耐病性品種 / トランスジエニック植物 / 溶菌酵素遺伝子 / トランスジェニック植物 / ダツラ / カイケイジオウ / Chichen egg lysozyme / Transformation / Antibacterial plant / Medicinal plant / タンパク質工学 / タンパク質のX線結晶解析 / タンパク質の構造 / タンパク質の耐熱安定性 / 酵素遺伝子の塩基配列 / 酵素の基質特異性 / タンパク質の化学修飾 / タンパク質のNMR / 遺伝子の塩基配列 / タンパク質の耐熱性 / タンパク質間特異的分子認識 / 部位特異的変異 / Protein Engineering / Structure of Protein / X-ray Crystallography of Protein / Heat Stability of Protein / Base Sequence of Gene / Substrate Specificity of Enzyme / NMR of Protein / Chemical Modification of Protein / リゾチーム(ムラミダーゼ) / 細菌リポ多糖(細菌内毒素) / リピドA / 歯周炎(歯周病) / 破骨細胞 / 免疫薬理 / 腫瘍壊死因子 / マイトゲン / 多クローン性B細胞活性化 / Lysozyme (Muramidase) / Lipopolysaccharide (Endotoxin) / Lipid A / Periodontitis (Periodontal Disease) / Osteoclasts / Immunopharmacology / 分子運動 / オーダーパラメーター / 15Nラベル化 / 安定同位体 / NMR(核磁気共鳴法) / 安定同位体ラベル化 / Pichia / 核磁気共鳴法(NMR) / ゆらぎ / fluctuation / activity / タンパク質 / 巻き戻し / 透析法 / IgG / リボヌクレアーゼA / タカアミラーゼA / エノラーゼ / 単鎖Fv / インクルージョンボディ / クエン酸シンターゼ / protein / folding / dialysis / immunoglobulin G / 酵素適合誘導 / pichia pastoris / リボヌクレアーゼT1 / ヒトヌクレアーゼ3 / 酵素誘導適合 / コドンユーセージ / ヒトリボクレアーゼ3 / ribonulease / induced fit / インターロイキン13 / アレルギー / 安定同位体ラベル / 核磁気共鳴法 / チオレドキシン / nuclear magnetic resonance / interleukin 13 / relaxation analysis / allergy / stable-isotope-labeling / 薬物代謝 / アルカロイド / タンニン / スフィンゴ糖脂質 / 血小板活性因子 / 構造決定 / 代謝産物 / 植物ポリフェノール / 海産動物糖脂質 / 立体化学 / ストリキニーネ / スコポラミン / グリコスフインゴリピド / プロスタグランジン / FT-NMR / Drugmetabolism / Alkaloid / Tannin / Glycosphingolipid / Platelet-Activating-Factor / Lysozyme / Proton Nuclear Magnetic Resonance Spectrometry Less

Establishment of high concentration Refolding of unstable proteinPrincipal Investigator
- Principal Investigator
  
  MATSUMOTO Toshihiko, 井本泰治
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Applied biochemistry
- Research Institution
  Sojo University
核磁気共鳴装置を用いたβアミロイドペプチドのリン酸イオンによる凝集抑制機構の解明
- Principal Investigator
  
  植田正
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Kyushu University
Analysis on mechanism of severe allergic reaction caused by SNP in interleukin 13 using NMR
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  KYUSHU UNIVERSITY
AnaIysis of dynamic behavior of ribonuclease upon ligand binding using high resolution NMR
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Kyushu University
カルシウム結合部位を導入したニワトリリゾチーム変異体を用いた再生初期構造の形成要因の解明Principal Investigator
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Research Institution
  Kyushu University
変異体を用いたリゾチームの構造構築過程の解析Principal Investigator
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
ランダム変異を用いたリゾチームのフォルディング情報の解析Principal Investigator
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
STRATEGY FOR DEPRESSION OF IRREVERSIBLE REACTIONS OF PEPTIDES OR PROTEINS AS MEDICINEPrincipal Investigator
- Principal Investigator
  
  IMOTO Taiji
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYUSHU UNIVERSITY
Construction of an effective renaturation method of denatured proteins based on a biological function
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Structural biochemistry
- Research Institution
  Kyushu University
ランダム変異を用いたリゾチームのフォルディング情報の解析Principal Investigator
- Principal Investigator
  
  井本泰治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Kyushu University
Interaction between Bacterial Endotoxin and Lysozyme
- Principal Investigator
  
  ITO Hiro-O, 古賀敏生
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Kyushu University
Analysis of dynamic behavior of mutant hen lysozyme with larger catalytic constant using high resolution NMR
- Principal Investigator
  
  UEDA Tadashi
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Biophysics
- Research Institution
  Kyushu University
Multi-disciplinary Approach for the Application of Protein Engineering
- Principal Investigator
  
  TONOMURA Ben'ichiro
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  応用微生物学・応用生物化学
- Research Institution
  KYOTO UNIVERSITY
Formation of antibacterial medicinal plants by transformation using lysozyme gene
- Principal Investigator
  
  SHOYAMA Yukihiro
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  KYUSHU UNIVERSITY
加水分解酵素の機能発現機構
- Principal Investigator
  
  SAKIYAMA Fumio
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  物質生物化学
- Research Institution
  Osaka University
Multiple approaches for the establishment of the basis of Protein Engineering.Principal Investigator
- Principal Investigator
  
  IMOTO Taiji
- Project Period (FY)
  1990 – 1991
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Study on the Renaturation of Mutant Lysozymes Expressed in Schericia Coli.
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  1989 – 1990
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
化学修飾および遺伝子工学による蛋白質のフォルディング過程の解析
- Principal Investigator
  
  YAMADA Hidenori
- Project Period (FY)
  1988
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  物質生物化学
- Research Institution
  Kyushu University
Molecular design of lysozyme for the improvement of protein function.Principal Investigator
- Principal Investigator
  
  IMOTO Taiji
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kyushu University
CHEMICAL STUDY OF PLANT AND ANIMAL CONSTITUENTS AND METABOLIC PRODUCTS
- Principal Investigator
  
  YOSHIMURA Hidetoshi
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  Chemical pharmacy
- Research Institution
  KYUSHU UNIVERSITY

All 2012 2010

All Journal Article Presentation

[Journal Article] Effect of protein concentration and pH on the chitinase activity of Tapes japonica lysozyme2010
- Author(s)
  Goto T, Abea Y, Imoto T, Uedaa T
- Journal Title
  
  Protein Peptide Let. 17
  
  Pages: 172-175
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580119
[Journal Article] Refolding of an unstable lysozyme by gradient removal of a solubilizer and gradient addition of a stabilizer2010
- Author(s)
  Kohyama K, Matsumoto T, and Imoto T
- Journal Title
  
  J. Biochem
  
  Volume: 143巻 Pages: 427-431
- NAID
  10027874720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580119
[Journal Article] Refolding of an unstable lysozyme by gradient removal of a solubilizer and gradient addition of a stabilizer2010
- Author(s)
  Kohyama K, Matsumoto T, Imoto T
- Journal Title
  
  J.Biochem. 143
  
  Pages: 427-431
- NAID
  10027874720
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21580119
[Presentation] 不安定タンパク質の効率的な再生法の確立2012
- Author(s)
  保田達哉, 野稲俊宏, 松元俊彦, 安藤祥司, 井本泰治
- Organizer
  日本農芸化学会
- Place of Presentation
  京都女子大
- Year and Date
  2012-03-24
- Data Source
  KAKENHI-PROJECT-21580119

1. UEDA Tadashi (90184928)

# of Collaborated Projects: 11 results

# of Collaborated Products: 0 results
2. HASHIMOTO Yoshio (50253472)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
3. SAKIYAMA Fumio (40029947)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
4. IWANAGA Sadaaki (90029942)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. ABE Yoshito (60315091)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
6. MATSUMOTO Toshihiko (60133568)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
7. YAMADA Hidenori (80037613)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. ASHIDA Tamaichi (10029936)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. ITO Hiro-O (40213079)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 伊東祐二 (60223195)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. YAMAURA Izumi (30133565)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. OHTSUKA Eiko (80028836)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. OHTA Takahisa (30011844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. SHOYAMA Yukihiro (70037604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. MIKI Takeyoshi (40037586)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. TONOMURA Ben'ichiro (20026545)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. ODA Jun-ichi (50027041)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. HIRATA Masato (60136471)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. KAWANO Keiichi (10136492)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. IZUHARA Kenji (00270463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. YOSHIMURA Hidetoshi (00037566)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. SAKAI Kiyoshi (90153840)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. KOMORI Tetsuya (80037572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. NISHIOKA Itsuo (20037568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. 高橋健治 (70011533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 鈴木紘一 (80011948)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. 勝部幸輝 (20032013)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. 門司晃 (00294942)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. 古賀敏生 (00037540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. KUROKI Ryota

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

IMOTO Taiji 井本 泰治

Research Projects

Research Products

Co-Researchers

Establishment of high concentration Refolding of unstable proteinPrincipal Investigator

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カルシウム結合部位を導入したニワトリリゾチーム変異体を用いた再生初期構造の形成要因の解明Principal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

変異体を用いたリゾチームの構造構築過程の解析Principal Investigator

Principal Investigator

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Research Institution

ランダム変異を用いたリゾチームのフォルディング情報の解析Principal Investigator

Principal Investigator

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Research Institution

STRATEGY FOR DEPRESSION OF IRREVERSIBLE REACTIONS OF PEPTIDES OR PROTEINS AS MEDICINEPrincipal Investigator

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Principal Investigator

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ランダム変異を用いたリゾチームのフォルディング情報の解析Principal Investigator

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IMOTO Taiji 井本泰治