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IMOTO Taiji  井本 泰治

ORCIDConnect your ORCID iD *help
Researcher Number 90038282
Other IDs
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Affiliation (based on the past Project Information) *help 2009: Sojo University, 生物生命学部, 教授
2003: Sojo University, Faculty of Engineering, Professor, 工学部, 教授
2002: 九州大学, 大学院・薬学研究院, 教授
2001: Kyushu Univ., Grad. School Pharm. Sci., Prof., 薬学研究院, 教授
2000: 九州大学, 大学院・薬学研究院, 教授 … More
1998: 九州大学, 大学院薬学研究科, 教授
1997: 九大, 教授
1995 – 1997: 九州大学, 大学院・薬学研究科, 教授
1986 – 1996: 九州大学, 薬学部, 教授 Less
Review Section/Research Field
Principal Investigator
Biological pharmacy / Applied biochemistry / 物質生物化学
Except Principal Investigator
物質生物化学 / Biological pharmacy / Physical pharmacy / Biological Sciences / 応用微生物学・応用生物化学 / 病態科学系歯学(含放射線系歯学) / Biophysics / Structural biochemistry / Chemical pharmacy
Keywords
Principal Investigator
リゾチーム / フォルディング / ランダムライブラリー / タンパク質 / NMR / cDNA / 変異タンパク質 / 構造形成機構 / 再生反応 / 巻き戻し … More / カルシウム結合部位 / アグリケーション / ラクトアルブミン / 再生 / 安定化剤 / 可溶化剤 / 不安定蛋白質 / タンパク質の再生 / グリセリン / 透析再生法 / 高濃度生成法 / 不安定タンパク質 / 高濃度再生法 / タンパク質工学 / X線結晶解析 / アミノ酸置換 / 化学修飾 / 比較生化学 / タンパク質発現系 / アルドラ-ゼ / NADHーシトクロムb5 / 血液凝固因子 / アロステリック現象 / T4エンドヌクレア-ゼ / ATPase. / 核酸修復酵素 / Lー乳酸脱水素酵素 / ATPase / キメラタンパク質 / モジュ-ル / Znープロテア-ゼ / ボ-マン・バ-ク型インヒビタ- / Protein Engineering / X-ray crystallography / Replacement of amino acid / Chemical modification / Comparative biochemistry / Protein expression system / 不可逆化学反応 / 添加剤 / ペプチド / スクロース / トレハロース / トリフルオロエタノール / 不可逆失活抑制 / Asn-Gly配列 / Asp-Gly配列 / IRREVERSIBLE CHMEICAL REACTION / ADDITIVE / PROTEIN / PEPTIDE / SUCROSE / TREHALOSE / ニワトリリゾチ-ム / 蛋白質工学 / 変異リゾチ-ム / アミノ酸配列 / 蛋白質機能 / ニワトリリゾチーム / 遺伝子工学 / 大腸菌 / 酵母 / 変異リゾチーム / 酵素機能 / Chicken lysozyme / Protein engineering / Mutant lysozyme / Amino acid sequence / Protein function / Protein folding … More
Except Principal Investigator
NMR / リゾチーム / フォルディング / 遺伝子工学 / 大腸菌 / lysozyme / order parameter / ^<15>N labeling / 緩和解析 / Pichia pastoris / 核磁気共鳴 / 加水分解酵素 / 機能発現機構 / 基質特異性 / アクロモバクタープロテアーゼI / リボヌクレアーゼ / ホスホリパーゼA_2 / 非ペプシン型プロテアーゼ / 立体構造の相同性 / β-アミロイドペプチド / 凝集反応 / ニワトリリゾチーム / 化学修飾 / ニワトリリゾチ-ム / N末端プロセッシング / デアミデ-ション / 巻戻し / SS-SH交換反応 / 変異リゾチ-ム / Gene engineering / Chicken lysozyme / Eschericia coli / Processing of N-terminal methionine / Deaminated / Renaturation / 溶菌酵素 / 遺伝子組み換え / 耐病性 / 薬用植物 / リゾチーム遺伝子 / 耐病性品種 / トランスジエニック植物 / 溶菌酵素遺伝子 / トランスジェニック植物 / ダツラ / カイケイジオウ / Chichen egg lysozyme / Transformation / Antibacterial plant / Medicinal plant / タンパク質工学 / タンパク質のX線結晶解析 / タンパク質の構造 / タンパク質の耐熱安定性 / 酵素遺伝子の塩基配列 / 酵素の基質特異性 / タンパク質の化学修飾 / タンパク質のNMR / 遺伝子の塩基配列 / タンパク質の耐熱性 / タンパク質間特異的分子認識 / 部位特異的変異 / Protein Engineering / Structure of Protein / X-ray Crystallography of Protein / Heat Stability of Protein / Base Sequence of Gene / Substrate Specificity of Enzyme / NMR of Protein / Chemical Modification of Protein / リゾチーム(ムラミダーゼ) / 細菌リポ多糖(細菌内毒素) / リピドA / 歯周炎(歯周病) / 破骨細胞 / 免疫薬理 / 腫瘍壊死因子 / マイトゲン / 多クローン性B細胞活性化 / Lysozyme (Muramidase) / Lipopolysaccharide (Endotoxin) / Lipid A / Periodontitis (Periodontal Disease) / Osteoclasts / Immunopharmacology / 分子運動 / オーダーパラメーター / 15Nラベル化 / 安定同位体 / NMR(核磁気共鳴法) / 安定同位体ラベル化 / Pichia / 核磁気共鳴法(NMR) / ゆらぎ / fluctuation / activity / タンパク質 / 巻き戻し / 透析法 / IgG / リボヌクレアーゼA / タカアミラーゼA / エノラーゼ / 単鎖Fv / インクルージョンボディ / クエン酸シンターゼ / protein / folding / dialysis / immunoglobulin G / 酵素適合誘導 / pichia pastoris / リボヌクレアーゼT1 / ヒトヌクレアーゼ3 / 酵素誘導適合 / コドンユーセージ / ヒトリボクレアーゼ3 / ribonulease / induced fit / インターロイキン13 / アレルギー / 安定同位体ラベル / 核磁気共鳴法 / チオレドキシン / nuclear magnetic resonance / interleukin 13 / relaxation analysis / allergy / stable-isotope-labeling / 薬物代謝 / アルカロイド / タンニン / スフィンゴ糖脂質 / 血小板活性因子 / 構造決定 / 代謝産物 / 植物ポリフェノール / 海産動物糖脂質 / 立体化学 / ストリキニーネ / スコポラミン / グリコスフインゴリピド / プロスタグランジン / FT-NMR / Drugmetabolism / Alkaloid / Tannin / Glycosphingolipid / Platelet-Activating-Factor / Lysozyme / Proton Nuclear Magnetic Resonance Spectrometry Less
  • Research Projects

    (20 results)
  • Research Products

    (4 results)
  • Co-Researchers

    (30 People)
  •  Establishment of high concentration Refolding of unstable proteinPrincipal Investigator

    • Principal Investigator
      MATSUMOTO Toshihiko, 井本 泰治
    • Project Period (FY)
      2009 – 2011
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Applied biochemistry
    • Research Institution
      Sojo University
  •  核磁気共鳴装置を用いたβアミロイドペプチドのリン酸イオンによる凝集抑制機構の解明

    • Principal Investigator
      植田 正
    • Project Period (FY)
      2002
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Review Section
      Biological Sciences
    • Research Institution
      Kyushu University
  •  Analysis on mechanism of severe allergic reaction caused by SNP in interleukin 13 using NMR

    • Principal Investigator
      UEDA Tadashi
    • Project Period (FY)
      2002 – 2003
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      KYUSHU UNIVERSITY
  •  AnaIysis of dynamic behavior of ribonuclease upon ligand binding using high resolution NMR

    • Principal Investigator
      UEDA Tadashi
    • Project Period (FY)
      2000 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Physical pharmacy
    • Research Institution
      Kyushu University
  •  カルシウム結合部位を導入したニワトリリゾチーム変異体を用いた再生初期構造の形成要因の解明Principal Investigator

    • Principal Investigator
      井本 泰治
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas (A)
    • Research Institution
      Kyushu University
  •  変異体を用いたリゾチームの構造構築過程の解析Principal Investigator

    • Principal Investigator
      井本 泰治
    • Project Period (FY)
      1997
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  ランダム変異を用いたリゾチームのフォルディング情報の解析Principal Investigator

    • Principal Investigator
      井本 泰治
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  STRATEGY FOR DEPRESSION OF IRREVERSIBLE REACTIONS OF PEPTIDES OR PROTEINS AS MEDICINEPrincipal Investigator

    • Principal Investigator
      IMOTO Taiji
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KYUSHU UNIVERSITY
  •  Construction of an effective renaturation method of denatured proteins based on a biological function

    • Principal Investigator
      UEDA Tadashi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Research Field
      Structural biochemistry
    • Research Institution
      Kyushu University
  •  ランダム変異を用いたリゾチームのフォルディング情報の解析Principal Investigator

    • Principal Investigator
      井本 泰治
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Scientific Research on Priority Areas
    • Research Institution
      Kyushu University
  •  Interaction between Bacterial Endotoxin and Lysozyme

    • Principal Investigator
      ITO Hiro-O, 古賀 敏生
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      病態科学系歯学(含放射線系歯学)
    • Research Institution
      Kyushu University
  •  Analysis of dynamic behavior of mutant hen lysozyme with larger catalytic constant using high resolution NMR

    • Principal Investigator
      UEDA Tadashi
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      Kyushu University
  •  Multi-disciplinary Approach for the Application of Protein Engineering

    • Principal Investigator
      TONOMURA Ben'ichiro
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      応用微生物学・応用生物化学
    • Research Institution
      KYOTO UNIVERSITY
  •  Formation of antibacterial medicinal plants by transformation using lysozyme gene

    • Principal Investigator
      SHOYAMA Yukihiro
    • Project Period (FY)
      1993 – 1995
    • Research Category
      Grant-in-Aid for Developmental Scientific Research (B)
    • Research Field
      Biological pharmacy
    • Research Institution
      KYUSHU UNIVERSITY
  •  加水分解酵素の機能発現機構

    • Principal Investigator
      SAKIYAMA Fumio
    • Project Period (FY)
      1992
    • Research Category
      Grant-in-Aid for Co-operative Research (B)
    • Research Field
      物質生物化学
    • Research Institution
      Osaka University
  •  Multiple approaches for the establishment of the basis of Protein Engineering.Principal Investigator

    • Principal Investigator
      IMOTO Taiji
    • Project Period (FY)
      1990 – 1991
    • Research Category
      Grant-in-Aid for Co-operative Research (A)
    • Research Field
      物質生物化学
    • Research Institution
      Kyushu University
  •  Study on the Renaturation of Mutant Lysozymes Expressed in Schericia Coli.

    • Principal Investigator
      YAMADA Hidenori
    • Project Period (FY)
      1989 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyushu University
  •  化学修飾および遺伝子工学による蛋白質のフォルディング過程の解析

    • Principal Investigator
      YAMADA Hidenori
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      物質生物化学
    • Research Institution
      Kyushu University
  •  Molecular design of lysozyme for the improvement of protein function.Principal Investigator

    • Principal Investigator
      IMOTO Taiji
    • Project Period (FY)
      1988 – 1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Biological pharmacy
    • Research Institution
      Kyushu University
  •  CHEMICAL STUDY OF PLANT AND ANIMAL CONSTITUENTS AND METABOLIC PRODUCTS

    • Principal Investigator
      YOSHIMURA Hidetoshi
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Chemical pharmacy
    • Research Institution
      KYUSHU UNIVERSITY

All 2012 2010

All Journal Article Presentation

  • [Journal Article] Effect of protein concentration and pH on the chitinase activity of Tapes japonica lysozyme2010

    • Author(s)
      Goto T, Abea Y, Imoto T, Uedaa T
    • Journal Title

      Protein Peptide Let. 17

      Pages: 172-175

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580119
  • [Journal Article] Refolding of an unstable lysozyme by gradient removal of a solubilizer and gradient addition of a stabilizer2010

    • Author(s)
      Kohyama K, Matsumoto T, and Imoto T
    • Journal Title

      J. Biochem

      Volume: 143巻 Pages: 427-431

    • NAID

      10027874720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580119
  • [Journal Article] Refolding of an unstable lysozyme by gradient removal of a solubilizer and gradient addition of a stabilizer2010

    • Author(s)
      Kohyama K, Matsumoto T, Imoto T
    • Journal Title

      J.Biochem. 143

      Pages: 427-431

    • NAID

      10027874720

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21580119
  • [Presentation] 不安定タンパク質の効率的な再生法の確立2012

    • Author(s)
      保田達哉, 野稲俊宏, 松元俊彦, 安藤祥司, 井本泰治
    • Organizer
      日本農芸化学会
    • Place of Presentation
      京都女子大
    • Year and Date
      2012-03-24
    • Data Source
      KAKENHI-PROJECT-21580119
  • 1.  UEDA Tadashi (90184928)
    # of Collaborated Projects: 11 results
    # of Collaborated Products: 0 results
  • 2.  HASHIMOTO Yoshio (50253472)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 3.  SAKIYAMA Fumio (40029947)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  IWANAGA Sadaaki (90029942)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  ABE Yoshito (60315091)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  MATSUMOTO Toshihiko (60133568)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 3 results
  • 7.  YAMADA Hidenori (80037613)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  ASHIDA Tamaichi (10029936)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 9.  ITO Hiro-O (40213079)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 10.  伊東 祐二 (60223195)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 11.  YAMAURA Izumi (30133565)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  OHTSUKA Eiko (80028836)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  OHTA Takahisa (30011844)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  SHOYAMA Yukihiro (70037604)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  MIKI Takeyoshi (40037586)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  TONOMURA Ben'ichiro (20026545)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  ODA Jun-ichi (50027041)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  HIRATA Masato (60136471)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 19.  KAWANO Keiichi (10136492)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 20.  IZUHARA Kenji (00270463)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 21.  YOSHIMURA Hidetoshi (00037566)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 22.  SAKAI Kiyoshi (90153840)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 23.  KOMORI Tetsuya (80037572)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 24.  NISHIOKA Itsuo (20037568)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 25.  高橋 健治 (70011533)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 26.  鈴木 紘一 (80011948)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 27.  勝部 幸輝 (20032013)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 28.  門司 晃 (00294942)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 29.  古賀 敏生 (00037540)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 30.  KUROKI Ryota
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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