YAMADA Shizuo 山田静雄

… Alternative Names

山田静雄ヤマダシズオ

山田靜雄ヤマダシズオ

Less

Researcher Number	80106434
Other IDs
External Links
Affiliation (Current)	2025: 静岡県立大学, 薬学部, 特任教授
Affiliation (based on the past Project Information) *help	2011 – 2013: 静岡県立大学, 薬学部, 教授 2006 – 2007: 静岡県立大学, 薬学部, 教授 2004: University of Shizuoka, School of Pharmaceutical Sciences, Department of Biopharmacy, Professor and Chairman, 薬学部, 教授 2003: 静岡県立大学, 薬学部, 助教授 1999 – 2000: 静岡県立大学, 薬学部, 助教授 … More 1995 – 1996: 静岡県立大学, 薬学部, 助教授 1991 – 1992: 静岡県立大学, 薬学部, 助教授 1988 – 1989: 静岡県立大学, 薬学部, 講師 1987: School of Pharmaceutical Sciences, University of Shizuoka, 薬学部, 助手 1986: 静岡薬大, 薬学部, 助手 1986: Shizuoka College of Pharmacy, 薬学部, 助手 Less
Review Section/Research Field	Principal Investigator 応用薬理学・医療系薬学 / General pharmacology / Urology / Applied pharmacology Except Principal Investigator Biological pharmacy / General pharmacology
Keywords	Principal Investigator ムスカリン性受容体 / Radioreceptor assay / ラジオレセプターアッセイ / EDTA / 受容体結合測定法 / Neurotransmitter receptors / Overactive bladder / シストメトリー法 / 受容体結合パラメータ / 脊椎損傷モデル … More / 受容体 / 前立腺肥大 / Urinary bladder / 膀胱 / ラジオレセプタ-アッセイ / Non-dihydropyridine Ca^<++> antagonists / Divalent cations / (+)-[^3H]PN 200-110 / [^3H]nitrendipine / Ca^<++> antagonist receptor / Coronary artery / べラパミール / ジルチアゼム / ^3H-ニトレンジピン / ^3H-PN200-110 / ^3H-ニトレソジピン / Ca拮抗薬受容体 / 冠動脈 / 非ジヒドロピリジン系Ca^<++>拮抗薬受容体 / 二価陽イオン / (+)ー^3HーPN200ー110 / ^3Hーニトレンジピン / Ca^<++>拮抗薬受容体 / 冠状動脈 / clonidine / _2-adrenoceptors / radioreceptor assay / medulla oblongata / Spontaneously hypertensive rats(SHR, SHRSP) / 【α_2】-アドレナリン受容体 / カテコールアミン作働性神経活性 / クロニジン / α_2-アドレナリン受容体 / 延髄 / 高血圧自然発症ラット(SHR,SHRSP) / Interstitial / Bladder outlet obstruction / Cerebral infarction / Benign urostatic hvnernlasia / 抗コリン薬 / 膀胱ムスカリン性受容体 / 尿道閉塞 / 脳梗塞 / 脊髄損傷 / 受容体拮抗薬 / ATP受容体 / アンギオテンシン受容体 / 間質性膀胱炎 / 尿道部分閉塞 / 排尿障害 / Cystometry method / Receptor binding parameters / Rat model with spinal cord injury / Benign prostatic hypertrphy / 最大結合部位数 / 解離定数 / [3H]NMS / 過活動膀胱 / Receptor binding / submaxillary gland / Muscarinic receptors / Transdermal therapeutic sys em / Oxybutynin / Propiverine / Urinary incontinence / プロピベリン / 経皮吸収剤 / 唾液腺 / 経皮吸収製剤 / オキシブチニン / 抗コリン剤 / 頻尿・尿失禁 / Calcium level / Brain pharmacokinetics / Calcium antagonist receptors / Amlodipine / Nimodipine / Calcium antagonists / Deficits of learning and memory / Senescence-accelerated mouse / 受動回避反応試験 / 学習・記憶障害 / カルシウム量 / 脳内動態 / カルシウム拮抗薬受容体 / アムロジピン / ニモジピン / カルシウム拮抗薬 / 学習記憶障害 / 老化促進マウス / Alpha_l adrenoceptor subtype / Human aorta / Alpha_l antagonists / [^3H] bunazosin / [^3H] prazosin / Alpha_l adrenoceptors / Human prostate / レセプタ-結合動態 / α_1^-拮抗薬 / α_1^-レセプタ- / レセプター結合動態 / 〔^3H〕プラゾシン / α_1-レセプター / 前立腺 / 前立腺肥大症 / α_1-レセプターサブタイプ / ヒト大動脈 / α_1-拮抗薬 / [ ^3H]ブナゾシン / [ ^3H]プラゾシン / α_1-アドレナリンレセプター / ヒト前立腺 / 薬物動態 / 血漿中薬物濃度 / 緑茶カテキン / 体内動態 / 血漿中濃度 / 日本人 / スタチン剤 / シトクロームP-450 / 薬物代謝酵素 / 相互作用 / シンバスタチン / カテキン類 / 緑茶 … More Except Principal Investigator rats / Cyclic AMP / Cyclic AMP-dependent protein kinase / 17 <beta> -Estradiol / Ovariectomy / Adipose tissue / Cholesterol esterase / C-AMP / 去勢 / ラット / C-AMP依存性プロテインキナーゼ / エストラジオール / 卵巣摘出 / 脂肪組織 / コレステロールエステラーゼ / Receptor / Acetylcholine / Bioactive molecule / Brain and Neuron / Neuroscience / Pharmaceutical Sciences / Pharmacology / ムスカリン受容体の弛緩機構 / 膜胱括約筋 / 受容体 / アセチルコリン / 生体分子 / 脳・神経 / 神経科学 / 薬学 / 薬理学 Less

Translational research of phama and food by greenteaPrincipal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  2011 – 2012
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Applied pharmacology
- Research Institution
  University of Shizuoka
Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.
- Principal Investigator
  
  FUJII Takeshi, MATSUI Minoru
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General pharmacology
- Research Institution
  Doshisha Women's College of Liberal Arts
  The University of Tokyo
Analysis of urinary dysfunction and drug discovery by in vivo measurement of drug-receptor bindingPrincipal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General pharmacology
- Research Institution
  University of Shizuoka
Characterization of neurotransmitter receptors in overactive bladder and drug discoveryPrincipal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Urology
- Research Institution
  University of Shizuoka
Development of therapeutic agents for urinary incontinence by in vivo analysis of dru-receptor binding characteriticsPrincipal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  University of Shizuoka
Brain pharmacokinetics and receptor binding characcteristics of calcium antagonists for improvement of brain dysfunctionPrincipal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  Sch.of Pharm.Sci., Univ.of Shizuoka
Characterization of prostatic alpha-l adrenoceptors in human benign prostatic hypertrophy.Principal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  School of Pharmaceutical Sciences, University of Shizuoka
Characterization of calcium antagonist receptors in coronary arteryPrincipal Investigator
- Principal Investigator
  
  YAMADA Shizuo
- Project Period (FY)
  1988 – 1989
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  School of Pharmaceutical Sciences, University of Shizuoka
Studies on the role of medullary alpha-2 adrenoceptors in experimental hypertensionPrincipal Investigator
- Principal Investigator
  
  YAMADA SHIZUO
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  応用薬理学・医療系薬学
- Research Institution
  School of Pharmaceutical Sciences, University of Shizuoka
  Shizuoka College of Pharmacy
Regulation of cholesterol esterase activity in the adipose tissue by 17 <beta> -estradiol
- Principal Investigator
  
  TOMITA Takako
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Biological pharmacy
- Research Institution
  Shizuoka College of Pharmacy

All 2013 2012 2011 2007 2006 2005 2004 Other

All Journal Article Presentation Book

[Book] 第2章食品の機能と薬物.第2節薬物と栄養の相互作用. 国民栄養白書 2012年版 (中村丁次、門脇孝監修)(vol 20)2012
- Author(s)
  山田静雄、木苗直秀
- Publisher
  (株)日本医療企画
- Data Source
  KAKENHI-PROJECT-23659287
[Book] クスリのことがわかる本-クスリを扱う人のための医薬品作用学2004
- Author(s)
  渡辺泰雄, 梅垣敬三, 山田静雄
- Total Pages
  185
- Publisher
  地人書館
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Effects of Green Tea Catechins on Cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A Activities in Human Liver and Intestinal Microsomes2013
- Author(s)
  Shingen Misaka, Keisuke Kawabe, Satomi Onoue, Jose Pablo Werba, Monica Giroli, Sekihiro Tamaki, Toshiyuki Kan, Junko Kimura, Hiroshi Watanabe, Shizuo Yamada
- Journal Title
  
  Drug Metab. Pharmacokinet
  
  Volume: 28 Pages: 244-9
- NAID
  210000170598
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Development of rapid and simultaneous quantitative method for green tea catechins on the bioanalytical study using UPLC/ESI-MS2013
- Author(s)
  Shingen Misaka, Keisuke Kawabe, Satomi Onoue, Sekihiro Tamaki, Jose P. Werba, Monica Giroli, Junko Kimura, Hiroshi Watanabe, Shizuo Yamada
- Journal Title
  
  Biomed.Chromatogr
  
  Volume: 27 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Effects of green tea catechins on cytochrome P450 2B6, 2C8, 2C19, 2D6, and 3A activities in human liver and intestinal microsomes.2013
- Author(s)
  Shingen Misaka,Keisuke Kawabe,Satomi Onoue,Jose Pablo Werba,Monica Giroli,Sekimoto Tamaki,Toshiyuki Kan,Junko Kimura, Hiroshi Watanabe,Shizuo Yamada
- Journal Title
  
  Drug Metab Pharmacokinet
  
  Volume: in press
- NAID
  210000170598
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Effects of green tea extracts and (-)-epiga llocatechin 3-gallae on pharmacokinetics of nadolol in rats2013
- Author(s)
  Shingen Misaka, N Miyazaki, T Fukushi ma, Shizuo Yamada and Junko Kimura
- Journal Title
  
  Phytomedicine
  
  Volume: 20 Pages: 1247-1250
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Effects of Green Tea Catechins on Cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A Activities in Human Liver and Intestinal Microsomes2013
- Author(s)
  22. Shingen Misaka, Keisuke Kawabe, Satomi Onoue, José Pablo Werba, Monica Giroli, Sekihiro Tamaki, Toshiyuki Kan, Junko Kimura, Hiroshi Watanabe, Shizuo Yamada
- Journal Title
  
  Drug Metab. Pharmacokinet.
  
  Volume: 28 Pages: 244-249
- NAID
  210000170598
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Development of rapid and simultaneous quantitative method for green tea catechins on the bioanalytical study using UPLC/ESI-MS2012
- Author(s)
  Shingen Misaka,Keisuke Kawabe,Satomi Onoue,Jose Pablo Werba,Monica Giroli,Junko Kimura,Hiroshi Watanabe, Shizuo yamada
- Journal Title
  
  Biomed.Chromatogr
  
  Volume: 27 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Development of rapid and simultaneous quantitative method for green tea catechins on the bioanalytical study using UPLC/ESI-MS2012
- Author(s)
  Shingen Misaka, Keisuke Kawabe, Satomi Onoue, Jose Pablo Werba, Monica Giroli, Junko Kimura, Hiroshi Watanabe, Shizuo Yamada
- Journal Title
  
  Biomed. Chromatogr
  
  Volume: 27 Pages: 1-6
- Data Source
  KAKENHI-PROJECT-23659287
[Journal Article] Comparative measurement of spinal CSF microdialysate concentrations and concomitant antinociception of morphine and morphine-6β-glucuronide in rats.2007
- Author(s)
  Takashi, Okura, Noriyuki, Komiyama, Yuki, Morita, Midori, Kimura, Yoshiharu, Deguchi, Shizuo, Yamada
- Journal Title
  
  Life Sci 80
  
  Pages: 1319-1326
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Bioactive analogues and drug delivery systems of vasoactive intestinal peptide (VIP) for the treatment of asthma/COPD.2007
- Author(s)
  Satomi, Onoue, Shizuo, Yamada, Takehiko, Yajima
- Journal Title
  
  Peptides 28
  
  Pages: 1640-1650
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Comparative evaluation of central muscarinic receptor binding activity byoxybutynin,tolterodine and darifenacin used to treat overactive bladder2007
- Author(s)
  Tomomi Oki, Aiko Kageyama, Yukiko Takagi, Shinya Uchida and Shizuo Yamada
- Journal Title
  
  J.Urol. 177
  
  Pages: 766-770
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Binding activities by propiverine and its N-oxide metabolites of voltage-dependent L-type calcium channel antagonist receptors in the rat bladder and brain2007
- Author(s)
  Shinya, Uchida, Souhei, Kurosawa, Tomomi, Fujino (Oki), Yoshihisa, Kato Masato, Nanri, Kenichiro, Yoshida, Shizuo, Yamada
- Journal Title
  
  Life Sci 80
  
  Pages: 2454-2460
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Comparative evaluation of central muscarinic receptor binding activity byoxybutynin, tolterodine and darifenacin used to treat overactive bladder2007
- Author(s)
  Tomomi Oki, Aiko Kageyama, Yukiko Takagi, Shinya Uchida and Shizuo Yamada:
- Journal Title
  
  J. Urol. 177
  
  Pages: 766-770
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Binding activities by propiverine and its N-oxide metabolites of voltage-dependent L-type calcium channel antagonist receptors in the rat bladder and brain2007
- Author(s)
  Shinya Uchida, Souhei Kurosawa, Tomomi Fujino(Tomomi Oki), Yoshihisa Kato, Masato Nanri, Kenichiro Yoshida and Shizuo Yamada
- Journal Title
  
  Life Sci. 80
  
  Pages: 2454-2460
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] A Novel mechanism for polychlorinated biphenyl-induced decrease in serum throxine level in rats.2007
- Author(s)
  Yoshihisa, Kato, Shin-ichi, Ikushiro, Rie, Takiguchi, Koichi, Haraguchi, Nobuyuki, Koga, Shinya, Uchida, Toshiyuki, Sakaki, Shizuo, Yamada, Jun, Kanno, Masakuni, Degawa
- Journal Title
  
  Drug Metab. Dispos 35
  
  Pages: 1949-1955
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Comparative evaluation of central muscarinic receptor binding activity by oxybutynin, tolterodine and darifenacin used to treat overactive bladder2007
- Author(s)
  Tomomi, Oki, Aiko, Kageyama, Yukiko, Takagi, Shinya, Uchida, Shizuo, Yamada
- Journal Title
  
  J. Urol 177
  
  Pages: 766-770
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Urodynamics and bladder muscarinic receptors in rats with cerebral infarction and bladder outlet obstruction2007
- Author(s)
  Shuji Maruyama, Souhei Kurosawa, Yukiko Takagi, Tomomi Oki, Yukiko Noguchi, Masashi Ukai, Hironori Yuyama, Akiyoshi Ohtake, Masanori Suzuki, Masao Sasayama and Shizuo Yamada
- Journal Title
  
  Neurosci.Lett. 414
  
  Pages: 80-84
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] from plasma concentrations of silodosin, tamsulosin and terazosin to treat urinary obstruction in benign prostatic hyperplasia.Biol.2007
- Author(s)
  Shizuo, Yamada, Yasuhiro, Kato, Takashi, Okura, Yoshiyuki, Kagawa, Kazuki, Kawabe Prediction of a_1-adrenoceptor occupancy in the human prostate
- Journal Title
  
  Pham. Bull 30
  
  Pages: 1237-1241
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Urodynamics and bladder muscarinic receptors in rats with cerebral infarction and bladder outlet obstruction2007
- Author(s)
  Shuji, Maruyama, Souhei, Kurosawa, Yukiko, Takagi, Tomomi, Oki, Yukiko, Noguchi, Masashi, Ukai, Hironori, Yuyama, Akiyoshi, Ohtake, Masanori, Suzuki Masao, Sasayama, Shizuo, Yamada
- Journal Title
  
  Neurosci. Lett 414
  
  Pages: 80-84
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Urodynamics and bladder muscarirnic receptors in rats with cerebral infarction and bladder outlet obstruction2007
- Author(s)
  Shuji Maruyama, Souhei Kurosawa, Yukiko Takagi, Tomomi Oki, Yukiko Noguchi, Masashi Ukai, Hironori Yuyama, Akiyoshi Ohtake, Masanori Suzuki, Masao Sasayama and Shizuo Yamada
- Journal Title
  
  Neurosci. Lett. 414
  
  Pages: 80-84
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Binding activities by propiverine and its N-oxide metabolites of voltage-dependent L-type calcium channel antagonist receptors in the rat bladder and brain2007
- Author(s)
  Shinya Uchida, Souhei Kurosawa, Tomomi Fujino(Oki), Yoshihisa Kato, Masato Nanri, Kenichiro Yoshida and Shizuo Yamada
- Journal Title
  
  Life Sci. 80
  
  Pages: 2454-2460
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Muscarinic and alpha 1-adrenergic receptor binding characteristics of saw palmetto extract in rat lower urinary tract.2007
- Author(s)
  Mayumi, Suzuki, Tomomi, Oki, Tomomi, Sugiyama, Keizo, Umegaki, Shinya, Uchida, Shizuo, Yamada
- Journal Title
  
  Urology 69
  
  Pages: 1216-1220
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine2007
- Author(s)
  Shinya, Uchida, Yasuhiro, Kato, Kazufumi, Hirano, Yoshiyuki, Kagawa, Shizuo, Yamada
- Journal Title
  
  Life Sci 80
  
  Pages: 1635-1640
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Different effects of morphine and morphine-60-glucuronide on formalin-evoked spinal glutamate release in conscious and freely moving rats.2007
- Author(s)
  Takashi, Okura, Noriyuki, Komiyama, Yuki, Morita, Midori, Kimura, Shizuo, Yamada
- Journal Title
  
  Neurosci. Lett 415
  
  Pages: 169-173
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Human muscarinic receptor binding characteristics of antimucarinic agents to treat overactive bladder.2006
- Author(s)
  Shuji Maruyama, Tomomi Oki, Atsushi Otsuka, Hitoshi Sninbo, Seichiro Ozono, Shinji Kageyama, Isao Araki, Yuuki Mikami, Masayuki Takeda, Shizuo Yamada
- Journal Title
  
  J. Urol. 175
  
  Pages: 365-369
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] In vivo demonstration of M_3 muscarinic receptor subtype selectivity of darifenacin in mice.2006
- Author(s)
  Shizuo, Yamada, Shuji, Maruyama, Yukiko, Takagi, Shinya, Uchida, Tomomi, Oki
- Journal Title
  
  Life Sci 80
  
  Pages: 127-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Advantage for transdermal over oral oxybutynin to treat overactive bladder : muscarinic receptor binding, plasma drug concentration and salivary secretion.2006
- Author(s)
  Tomomi Oki, Ayako Toma-Okura, Shizuo Yamada)
- Journal Title
  
  J. Pharmacol.Exp. Ther. 316
  
  Pages: 1137-1145
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Human muscarinic receptor binding characteristics of antimuscarinic agents to treat overactive bladder2006
- Author(s)
  Shuji Maruyama, Tomomi Oki, Atsushi Otsuka, Hitoshi Sninbo, Seichiro Ozono, Shinji Kageyama, Isao Araki, Yuuki Mikami, Masayuki Takeda and Shizuo Yamada
- Journal Title
  
  J.Urol. 175
  
  Pages: 365-369
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Demonstration of M_3 muscarinic receptor subtype selectivity of darifenacin in mice2006
- Author(s)
  Shizuo Yamada, Shuji Maruyama, Yukiko Takagi, Shinya Uchida, Tomomi Oki
- Journal Title
  
  Life Sci. 80
  
  Pages: 127-132
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Advantage for transdermal over oral oxybutynin to treat overactive bladder: muscarinic receptor binding, plasma drug concentration and salivary secretion.2006
- Author(s)
  Tomomi, Oki, Ayako, Toma-Okura, Shizuo, Yamada
- Journal Title
  
  J. Pharmacol. Exp. Ther 316
  
  Pages: 1137-1145
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Human muscarinic receptor binding characteristics of antimuscarinic agents to treat overactive bladder.2006
- Author(s)
  Shuji, Maruyama, Tomomi, Oki, Atsushi, Otsuka, Hitoshi, Sninbo, Seichiro, Ozono, Shinji, Kageyama, Isao, Araki, Yuuki, Mikami, Masayuki, Takeda, Shizuo, Yamada
- Journal Title
  
  J. Urol 175
  
  Pages: 365-369
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice2006
- Author(s)
  Tomomi Oki, Shuji Maruyama, Yukiko Takagi, Henry I.Yamamura and Shizuo Yamada
- Journal Title
  
  Eur.J.Pharmacol. 529
  
  Pages: 157-163
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Advantage for transdermal over oral oxybutynin to treat over active bladder : muscarinic receptor binding, plasma drug concentration and salivary secretion.2006
- Author(s)
  Tomomi Oki, Ayako Toma-Okura, Shizuo Yamada
- Journal Title
  
  J. Pharmacol. Exp. Ther. 316
  
  Pages: 1137-1145
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Comparative evaluation of exocrine muscarinic receptor binding characteristics and inhibition of salivation of solifbnacin in mice2006
- Author(s)
  Tomomi Oki, Chihiro Takeuchi and Shizuo Yamada
- Journal Title
  
  Biol.Pharm.Bull. 29
  
  Pages: 1397-1400
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Stereochemical diversity-oriented conformational restriction strategy. Development of potent histamine H_3 and/or H_4 receptor antagonists with a imidazolylcyclopropane structure.2006
- Author(s)
  Mizuki, Watanabe, Yuji, Kazuta, Hideki, Hayashi, Shizuo, Yamada, Akira, Matsuda, Satoshi, Shuto
- Journal Title
  
  J. Med. Chem 49
  
  Pages: 5587-5596
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Advantage for transdermal over oral oxybutynin to treat overactive bladder:muscarinic receptor binding,plasma drug concentration and salivary secretion2006
- Author(s)
  Tomomi Oki, Ayako Toma-Okura and Shizuo Yamada
- Journal Title
  
  J.Pharmacol.Exp.Ther. 316
  
  Pages: 1137-1145
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice.2006
- Author(s)
  Tomomi, Oki, Shuji, Maruyama, Yukiko, Takagi, Henry I., Yamamura, Shizuo, Yamada
- Journal Title
  
  Eur. J. Pharmacol 529
  
  Pages: 157-163
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice2006
- Author(s)
  Tomomi Oki, Shuji Maruyama, Yukiko Takagi, Henry I. Yamamura, Shizuo Yamada
- Journal Title
  
  Eur. J. Pharmacol. 529
  
  Pages: 157-163
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Demonstration of M_3 muscarinic receptor subtype selectivity of darifbnacin in mice2006
- Author(s)
  Shizuo Yamada, Shuji Maruyama, Yukiko Takagi, Shinya Uchida and Tomomi Oki
- Journal Title
  
  Life Sci. 80
  
  Pages: 127-132
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Human muscarinic receptor binding characteristics of antimuscarinic agents to treat overactive bladder.2006
- Author(s)
  Shuji Maruyama, Tomomi Oki, Atsushi Otsuka, Hitoshi Sninbo, Seichiro Ozono, Shinji Kageyama, Isao Araki, Yuuki Mikami, Masayuki Takeda, Shizuo Yamada
- Journal Title
  
  J. Urol. 175
  
  Pages: 365-369
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Comparative evaluation of exocrine muscarinic receptor binding characteristics and inhibition of salivation of solifenacin in mice.2006
- Author(s)
  Tomomi, Oki, Chihiro, Takeuchi, Shizuo, Yamada
- Journal Title
  
  Biol. Pharm. Bull 29
  
  Pages: 1397-1400
- NAID
  110005602309
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Development of dry powder inhalation system of novel vasoactive intestinal peptide (VIP) analogue for pulmonary administration2006
- Author(s)
  Yuki, Ohmori, Satomi, Onoue, Kosuke, Endo, Asami, Matsumoto, Shinya, Uchida, Shizuo, Yamada
- Journal Title
  
  Life Sci 79
  
  Pages: 138-143
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Characterization of muscarinic receptor binding and inhibition of salivation after oral administration of tolterodine in mice.2006
- Author(s)
  Tomomi Oki, Shuji Maruyama, Yukiko Takagi, Henry I, Yamamura, Shizuo Yamada
- Journal Title
  
  Eur. J. Pharmacol. 529
  
  Pages: 157-163
- Data Source
  KAKENHI-PROJECT-18390073
[Journal Article] Selective protection of curcumin against carbon tetrachloride-induced inactivation of hepatic cytochrome P450 isozymes in rats2006
- Author(s)
  Tomomi, Sugiyama, Jun-ichi, Nagata, Azumi, Yamagishi, Kaori, Endoh, Morio, Saito Kazuhiko, Yamada, Shizuo, Yamada, Keizo, Umegaki
- Journal Title
  
  Life Sci 78
  
  Pages: 2188-2193
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Monospecific antipeptide antibodies against human heptatic UDP-glucuronosyltransferase 1A subfamily (UGT1A) isoforms2006
- Author(s)
  Ikushiro, S, Emi, Y, Kato, Y, Shizuo, Yamada, Sakai, T
- Journal Title
  
  Drug Metab. Pharmacokinet 21
  
  Pages: 70-74
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Comparative evaluation of exocrine Muscatine receptor binding characteristics and inhibition of salivation of solifenacin in mice.2006
- Author(s)
  Tomomi Oki, Chihiro Takeuchi, Shizuo Yamada
- Journal Title
  
  Biol. Pharm. Bull. 29
  
  Pages: 1397-1400
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Effects of Ginkgo biloba extract on pharmacokinetics and pharmacodynamics of tolbutamide and midazolam in healthy volunteers.2006
- Author(s)
  Shinya, Uchida, Hiroshi, Yamada, Xiao, Dong, Li, Syuji, Maruyama, Yuki, Ohmori, Tomomi, Oki, Hiroshi, Watanabe, Keizo, Umegaki, Kyoichi, Ohashi, Shizuo, Yamada
- Journal Title
  
  J. Clin. Pharmacol 46
  
  Pages: 1290-1298
- NAID
  130005023904
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Journal Article] Muscarinic receptor binding, plasma concentration and inhibition of salivation after oral administration of novel antimuscarinic agent, solifenacin succinate2005
- Author(s)
  Oki T, Kimura R, Sato S, Miyata K, Yamada S
- Journal Title
  
  British Journal of Pharmacology (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] In vivo demonstration of muscarinic receptor binding activity of N-desethyl-oxybutynin, active metabolite of oxybutynin2005
- Author(s)
  Oki T, Kawashima A, Uchida M, Yamada S.
- Journal Title
  
  Life Sciences 76
  
  Pages: 2445-2456
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Muscarinic receptor binding, plasma concentration and inhibition of salivation after oral administration of novel antimuscarinic agent, solifenacin succinate.2005
- Author(s)
  Oki T, Kimura R, Sato S, Miyata K, Yamada S
- Journal Title
  
  British Journal of Pharmacology (in press)(印刷中)
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] In vivo demonstration of muscarinic receptor binding activity of N-desethyl-oxybutynin, active metabolite of oxybutynin2005
- Author(s)
  Oki T, Kawashima A, Uchida M, Yamada S
- Journal Title
  
  Life Sciences 76
  
  Pages: 2445-2456
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Quantitative analysis of binding parameters of [^3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice2005
- Author(s)
  Oki T, Takagi Y, Taketo MM, Manabe T, Matsui M, Yamada S
- Journal Title
  
  Molecular Brain Research 133
  
  Pages: 6-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Quantitative analysis of binding parameters of [^3H]N-methylscopolamine in central nervous system of muscarinic acetylcholine receptor knockout mice.2005
- Author(s)
  Oki T, Takagi Y, Taketo MM, Manabe T, Matsui M, Yamada S
- Journal Title
  
  Molecular Brain Research 133
  
  Pages: 6-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Muscarinic receptor binding, plasma concentration and inhibition of salivation after oral administration of novel antimuscarinic agent, solifenacin succinate.2005
- Author(s)
  Oki T, Kimura R, Sato S, Miyata K, Yamada S
- Journal Title
  
  British Journal of Pharmacology in press
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] 過活動膀胱治療薬のヒト膀胱ならびに耳下腺のムスカリン性受容体結合っ親和性2004
- Author(s)
  山田静雄, 隠岐知美, 木村良平, 大塚篤史, 影山慎二, 三神裕紀, 武田正之
- Journal Title
  
  日本排尿機能学会誌 15
  
  Pages: 178-185
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] 過活動膀胱治療薬のヒト膀胱ならびに耳下腺のムスカリン性受容体結合親和性2004
- Author(s)
  山田静雄, 隠岐知美, 木村良平, 大塚篤史, 影山慎二, 三神裕紀, 武田正之
- Journal Title
  
  日本排尿機能学会誌 15
  
  Pages: 178-185
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Modulaltion of phenotype of human prostatic stromal cells by transforming growth factor-betas2004
- Author(s)
  Hisataki, T., Itoh, N., Suzuki, K., Takahasi, A., Yamada, S.et al.
- Journal Title
  
  The Prostate 58
  
  Pages: 174-182
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Demonstration of bladder selective muscarinic receptor binding by intravesical oxybutynin to treat overactive bladder2004
- Author(s)
  Oki T, Kimura R, Saito M, Miyagawa Y, Yamada S
- Journal Title
  
  Journal of Urology 172
  
  Pages: 2059-2064
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15591703
[Journal Article] Functional analysis of muscarinic acetylcholine receptors using knockout mice2004
- Author(s)
  Matsui M, Yamada S, Oki T, Manabe T, Taketo MM, Ehlert FJ
- Journal Title
  
  Life Sciences (Review article) 75
  
  Pages: 2971-2981
- Data Source
  KAKENHI-PROJECT-15591703
[Presentation] Effect of comsumption of catechin-rich green tea on pharmacokinetics of simvastatin in helthy volunteers2013
- Author(s)
  S.Yamada, S.Misaka, K.Tanabe, A.osano, K.takeuchi, J.P.Werba, H.watanabe
- Organizer
  Pharma-nutrition 2013
- Place of Presentation
  シンガポール
- Data Source
  KAKENHI-PROJECT-23659287
[Presentation] 健常人における臨床薬の体内動態に及ぼすカテキン類高含有緑茶の影響2011
- Author(s)
  川邉圭佑、三坂眞元、竹内和彦、田邉健樹、小佐野郁香、乾直輝、尾上誠良、Jose P. Werba、木村純子、渡邉裕司、山田静雄
- Organizer
  第32回日本臨床薬理学会 (講演要旨集 p.S271)
- Place of Presentation
  浜松
- Year and Date
  2011-12-01
- Data Source
  KAKENHI-PROJECT-23659287
[Presentation] 健常人における臨床薬の体内動態に及ぼすカテキン類高含有緑茶の影響2011
- Author(s)
  川邉圭佑、三坂眞元、竹内和彦、田邉健樹、小佐野郁香、乾直輝、尾上誠良、Jose P. Werba、木村純子、渡邉裕司、山田静雄
- Organizer
  第32回日本臨床薬理学会、講演要旨集　p.S271、
- Place of Presentation
  浜松
- Data Source
  KAKENHI-PROJECT-23659287
[Presentation] ヒト臓器由来ミクロソームを用いた CYP2B6, CYP2C8, CYP2C19 および CYP3A 活性に対する緑茶カテキン類の阻害効果2011
- Author(s)
  川邉圭佑、三坂眞元、尾上誠良、山田静雄
- Organizer
  第9回日本機能性食品医用学会総会 (要旨集 p.137)
- Place of Presentation
  大阪
- Year and Date
  2011-12-11
- Data Source
  KAKENHI-PROJECT-23659287
[Presentation] Muscarinic receptor binding characteristics of novel anticholinergic agents directed toward the therapy of overactive bladder.2007
- Author(s)
  Yamada S
- Organizer
  80th Annual Meeting of Japanese Pharmacological Society
- Place of Presentation
  Nagoya
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390073
[Presentation] Structure-activity relationship of receptor binding of some 1,4-dihydropyridine derivatives2007
- Author(s)
  Shizuo, Yamada, Daiki, Takahashi, Luvsandorj, Oyunzul, Satomi, Onoue, Yoshihiko, Ito. Shinva, Uchida, Rahime, Simsek, Miyase, Gozde Gunduz, Cihat, Safak
- Organizer
  5th Mt. Symp. on Pharm. Chem
- Place of Presentation
  Istanbul
- Year and Date
  2007-09-05
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] 膀胱選択的ムスカリン受容体拮抗薬コハク酸ソリフェナシン(ベシケア◎)の基礎と臨床2007
- Author(s)
  山田静雄
- Organizer
  第80回日本薬理学会年会
- Place of Presentation
  名古屋
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390073
[Presentation] Antinociceptive effect of extracts of medical herbs in mice and their interaction with morphine2007
- Author(s)
  Shinya, Uchida, Keita, Hirai, Junko, Hanato, Yukiko, Shinme, Shizuo, Yamada
- Organizer
  The 3rd China-Japan Joint Meeting ofBasic and Clinical Pharmacology
- Place of Presentation
  Dailen, Chaina
- Year and Date
  2007-08-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Long-lasting analogues and drug delivery systems of vasoactive intestinal peptide for the treatment of COPD2007
- Author(s)
  Satomi, Onoue, Shingen, Misaka, Takehiko, Yajima, Shizuo, Yamada
- Organizer
  5th Mt. Symp. on Pharm. Chem
- Place of Presentation
  Istanbul
- Year and Date
  2007-09-07
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] 膀胱ムスカリン牲受容体を標的とした頻尿・尿失禁治療薬の受容体結合動態2007
- Author(s)
  山田静雄, 他2名
- Organizer
  第80回日本薬理学会年会シンポジウム「下部尿路障害治療薬-基礎と臨床」(名古屋)
- Place of Presentation
  名古屋
- Year and Date
  2007-03-16
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Direct quantification of muscarinic receptor subtypes in human detrusor muscle, mucosa and parotid gland by irreversible inactivation of M3 receptors by 4-DAMP musterd2007
- Author(s)
  Kazuhiro, Suzuki, Shuji, Maruyama, Masayuki, Takeda, Atsushi, Otsuka, Siichiro, Ozono, Shizuo, Yamada
- Organizer
  37th Annual Meeting of the Mt. Continence Soc.
- Place of Presentation
  Rotterdam, Netherlands
- Year and Date
  2007-08-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] In vivo analysis of drug-receptor binding characteristics in drug discovery2007
- Author(s)
  Shizuo, Yamada, Satomi, Onoue
- Organizer
  5th Int. Symp. on Pharm. Chem
- Place of Presentation
  Istanbul
- Year and Date
  2007-09-06
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] In vivo analysis of brain muscarinic receptor occupancy after oral oxybutynin in conscious rhesus monkey by using positron emission tomography (PET)2007
- Author(s)
  Shuji, Maruyama, Hideo, Tsukada, Shizuo, Yamada
- Organizer
  37th Annual Meeting of the Int. Continence Soc.
- Place of Presentation
  Rotterdam, Netherlands
- Year and Date
  2007-08-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Muscarinic and purinergic receptors are altered in the bladder of rat models with interstitial cystitis2006
- Author(s)
  Aiko, Kageyama, Tomomi, Oki, Luvsandorj, Oyunzul, Shohei, Kurosawa, Shizuo, Yamada
- Organizer
  Int. Continence Ann. Meeting
- Place of Presentation
  Christchurch , New Zealand
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Pharmacokinetic, Receptor binding and Pharmacodynamic Anlaysis of CNS Drugs2006
- Author(s)
  Shizuo, Yamada, Kazufumi, Hirano, Tomomi, Oki, Akihiko, Urayama, Shinya, Uchida
- Organizer
  CINP Asia Pacific Regional Meeting
- Place of Presentation
  Pattaya, Thailand
- Year and Date
  2006-03-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Comparative evaluation of human mucosa and detrusor muscarinic receptor binding by anticholinergic agents in the treatment of overactive bladder2006
- Author(s)
  Tomomi, Oki, Luvsandorj, Oyunzul, Kazuhiro, Suzuki, Aiko, Kageyama, Atsushi, Otsuka, Hitoshi, Shinbo, Seiichiro, Ozono, Shizuo, Yamada
- Organizer
  Int. Continence Ann. Meeting
- Place of Presentation
  Christchurch , New Zealand
- Year and Date
  2006-12-01
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] The active metabolite (DPr-P-4(N→O)) of propiverine hydrochloride may contribute to the bladder selectivity of this drug to treat patients with overactive bladder2006
- Author(s)
  Shizuo, Yamada, Tomomi, Oki, Shuji, Maruyama, Kenichiro, Yoshida, Masato, Nanri, Masayuki, Takeda
- Organizer
  Int. Continence Ann. Meeting
- Place of Presentation
  Christchurch , New Zealand
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Effects of Ursodeoxycholic acid on the CYP3A activity and pharmacokinetics of midazolam in rats and healthy volunteers2006
- Author(s)
  Shinya, Uchida, Shohei, Kurosawa, Shingen, Misaka, Hiroshi, Watanabe, Kyoichi, Ohashi Shizuo, Yamada
- Organizer
  The 1st Asia Pacific ISSX Meeting
- Place of Presentation
  Jeju, Korea
- Year and Date
  2006-05-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] A possible mechanism for the decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats2006
- Author(s)
  Yoshihisa, Kato, Shin-ichi, Ikushiro, Rie, Takiguchi, Sekihiro, Tamaki, Koichi, Haraguchi, Toshiyuki, Sakaki, Shizuo, Yamada, Jun, Kanno, Masakuni, Degawa
- Organizer
  26th International Symposium on Halogenated Persistent Organic Pollutants
- Place of Presentation
  Oslo, Norway
- Year and Date
  2006-08-21
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Effects of ursodeoxycholic acid on the CYP3A activity and pharmacokinetics of midazolam in rats2006
- Author(s)
  Shinva, Uchida, Shohei, Kurosawa, Shingen, Misaka, XiaoDong, Li, DongMei, Yan, Hiroshi, Watanabe, Kyoichi, Ohashi, Shizuo, Yamada
- Organizer
  The 15th World Congress of Pharmacology
- Place of Presentation
  Beijing, China
- Year and Date
  2006-07-04
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Hiroshi Watanabe Influences of CYP2C9 genotype on pharmacokinetics and pharmacodynamics of benzbromarone2006
- Author(s)
  Shinya, Uchida, Kayoko., Shimada, Shingen, Misaka, Don Mei, Yan, Xiao Dong, Li, Shinichiro, Nishio, Hiromitu, Imai, Kyoichi, Ohashi, Shizuo, Yamada
- Organizer
  2005 Annual Meeting ofAmerican Society for Clinical Pharmacologyand Therapeutic
- Place of Presentation
  Baltimore, USA
- Year and Date
  2006-03-08
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Plasma concentration and muscarinic receptor binding characteristics of novel anticholinergic agents directed toward the therapy of overactive bladder2006
- Author(s)
  Tomomi, Oki, Shizuo, Yamada
- Organizer
  The 15th World Congress of Pharmacolog
- Place of Presentation
  Beijing, China
- Year and Date
  2006-07-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Demonstration of muscarinic and nicotinic receptor binding acticities of acetylcholinesterase inhibitors to treat impaired detrusor contractility
- Author(s)
  Kazumi, Fushimi, Yuki, Ishida, Taketsugu, Harada, Yoshihiko, Ito, Saori, Nishijima, Kimio, Sugaya, Shizuo, Yamada
- Organizer
  37th Annual Meeting of the Int. Continence Soc.
- Place of Presentation
  Rotterdam, Netherlands
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Propiverine and oxybutynin inhibit Ca^<2+> influx mediated by the activation of a specific receptor, transient recepter potential vanilloid subtype 1 (TRPV1)
- Author(s)
  Aiko, Kageyama, Yusaku, Iwasaki, Tatsuo, Watanabe, Masato, Nanri, Kenichiro, Yoshida, Shizuo, Yamada
- Organizer
  37th Annual Meeting of the Int. Continence Soc.
- Place of Presentation
  Rotterdam, Netherlands
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237
[Presentation] Propiverine and its N-oxide metabolite bind significantly to L-type calcium channel antagonist receptors in rat bladder
- Author(s)
  Shizuo, Yamada, Yoshihiko, Ito, Tomomi, Fujino, Masato, Nanri, Kenichiro, Yoshida
- Organizer
  37th Annual Meeting of the Mt. Continence Soc.
- Place of Presentation
  Rotterdam, Netherlands
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590237

1. FUJII Takeshi (80255380)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. MATSUI Minoru (50282611)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. WATANABE Hiroshi (50262803)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. TAKATORI Yuki (90411090)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. TAKEUCHI Tadayoshi (00171611)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KAWASHIMA Koichiro (70095008)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OKI Tomomi (50405148)

# of Collaborated Projects: 1 results

# of Collaborated Products: 31 results
8. TOMITA Takako (30046263)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 渡邊裕司

# of Collaborated Projects: 0 results

# of Collaborated Products: 9 results

YAMADA Shizuo 山田 静雄

山田 静雄 ヤマダ シズオ

山田 靜雄 ヤマダ シズオ

Research Projects

Research Products

Co-Researchers

Translational research of phama and food by greenteaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Functional analysis of acetylcholine receptor using muscarinic receptor knockout mice.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of urinary dysfunction and drug discovery by in vivo measurement of drug-receptor bindingPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of neurotransmitter receptors in overactive bladder and drug discoveryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of therapeutic agents for urinary incontinence by in vivo analysis of dru-receptor binding characteriticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Brain pharmacokinetics and receptor binding characcteristics of calcium antagonists for improvement of brain dysfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of prostatic alpha-l adrenoceptors in human benign prostatic hypertrophy.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Characterization of calcium antagonist receptors in coronary arteryPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the role of medullary alpha-2 adrenoceptors in experimental hypertensionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Regulation of cholesterol esterase activity in the adipose tissue by 17 <beta> -estradiol

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 第2章 食品の機能と薬物.第2節 薬物と栄養の相互作用. 国民栄養白書 2012年版 (中村丁次、門脇 孝 監修)(vol 20)2012

Author(s)

Publisher

Data Source

[Book] クスリのことがわかる本-クスリを扱う人のための医薬品作用学2004

Author(s)

Total Pages

Publisher

Description

Data Source

[Journal Article] Effects of Green Tea Catechins on Cytochrome P450 2B6, 2C8, 2C19, 2D6 and 3A Activities in Human Liver and Intestinal Microsomes2013

Author(s)

Journal Title

NAID

YAMADA Shizuo 山田静雄

山田静雄ヤマダシズオ

山田靜雄ヤマダシズオ

[Book] 第2章食品の機能と薬物.第2節薬物と栄養の相互作用. 国民栄養白書 2012年版 (中村丁次、門脇孝監修)(vol 20)2012