KOYAMA Akio 小山哲夫

… Alternative Names

小山昭夫コヤマアキオ

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Researcher Number	80111384
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2010: Ibaraki Prefectural University of Health Science, 学長 2008 – 2010: Ibaraki Prefectural University of Health Science, 保健医療学部, 学長 2004: University of Tsukuba, Graduate School of Comprehensive Human Sciences, Professor of Medicine, 大学院・人間総合科学研究科, 教授 1996 – 2003: 筑波大学, 臨床医学系, 教授 1995: 筑波大学, 臨床医学系内科, 教授 1993 – 1994: 筑波大学, 臨床医学系, 教授 1986: Associate professor, Institute of Clinical Medicine University of Tsukuba, 臨床医学系, 助教授
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine Except Principal Investigator Kidney internal medicine / 内科学一般 / Kidney internal medicine / Experimental pathology
Keywords	Principal Investigator スーパー抗原 / IgA腎症 / 糸球体腎炎 / MRSA / adhesin / IgA2 / IgA1 / 血管炎 / ネフローゼ症候群 / 免疫複合体 … More / T細胞サブセット / IgA関連腎炎 / TCRVβ / cytokine / superantigen / エンテロトキシン / antignen / Staphylococcus Aureus / IgA neohropathy / low avidity antibody / high responder / S.aureus / MRSA感染後腎炎 / 黄色ブドウ球菌 / IgA-production / Th1 & Th2 type / Glomerular deposition of antigens / 30-35kDa protein / mouse strains / Immunoglobulin A nephropathy / 免疫遺伝学的背景 / Th1 ＆ Th2 cells / monoclonal Abs / Staphylococcus aureus / Th1 & Th2 cells / モデル動物 / IGA-RELATED NEPHRITIS / SUPER ANTIGEN / IMMUNE COMPLEX / MANNER OF ACTIVATION / T CELL SUBSET / VASCULITIS / NEPHROTIC SYNDROME / GLOMERUL ONEPHRITIS / 免役複合体 / T細胞サブヒット / 活性化機序 / superantigen-related nephritis / systemic vasculitis / post-MRSA glomerulonephritis / T cell receptor / メチシリン耐性ブドウ球菌 / スーパー抗原関連腎炎 / 全身性血管炎 / サイトカイン / T細胞レセプター / MRSA腎炎 / IgA免疫複合体沈着 / 高応答抗体産生性 / ブドウ球菌膜抗原 / MRSA関連腎症 / ヒトIgA腎症 / T細胞subsets / TCRV β repertoire / MRSA感染後腎炎(スーパー抗原関連腎炎:SARN) / T細胞活性化機序 / FACS解析 / TCRV βrepertoire / MRSA感染後腎炎(スーパー抗原関連腎炎) / 紫斑病性腎炎 / 高応答性抗体産生 / 低親和性IgA抗体 / ブドウ球菌細胞膜抗原 / staphylococcal enterotoxin / Cytokine / Super antigen-dilated glond culonephritis / Superantigen / T cell activation / 腎炎 / T細胞活性化 / HLAタイピング / MHCクラスII / 外毒素 / immune complex / double negative cell / T cell receptor V-β / glomerulonephritis / poloyclonal activation / MRSA infection / T cell-receptor … More Except Principal Investigator Mitochondrial DNA / ミトコンドリア / 糸球体上皮細胞 / Lynphokine / T cell Hybrydoma / Vascular permeability factor / Minimal Change Nephrotic Syndrome / リンパ球増殖促進因子 / リンホカイン / 血管透過性因子 / リポイドネフローゼ / deletion mutation / podocyte / oxidative stress / mitochondrial protein / mitochondria / Focal and segmental glomerular sclerosis / 欠失変異 / 酸化障害 / ミトコンドリア蛋白 / ミトコンドリアDNA / 巣状糸球体硬化症 / RABBIT MODEL OF LIGHT SHIELDED HEMODIALYSIS / NO OVERPRODUCTION / ENDOTHELIAL NOS / SINGLET OXYGEN / PLASMA LIPID PEROXIDES / DIALYZER / ULTRAVIOLET CUT FILM / LIGHT SHIELDED HEMODIALYSIS / 抗酸化能 / PCOOH / TBARS / 過酸化脂質 / 一酸化窒素 / UVカット透析 / 光遮断血液回路 / ウサギの遮光透析モデル / NO過剰産生 / 内皮型NOS / 1重項酸素 / 血中過酸化脂質 / ダイアライザー / 紫外線除去フィルム / 遮光透析 / Heteroplasmy / IgA nephropathy / glomerular sclerosis / Glomerulonephritis / glomerular epithelial cells / Focal and segmental glomerular sclerosis (FGS) / 膜性腎症 / IgA腎症 / 巣状糸球体硬化症様病変 / ミトコンドリア遺伝子 / 進展様式 / 糸球体腎炎 / Imaging of Free Radical / Hemodialysis / Puromycin Aminonucleoside / Electrochemical Method / Chemiluminescence / Griess Method / Electron Spin Resonance / Nitric Cxide / 蛋白尿 / アミノヌクレオシド・ピュロマイシン / マクロファージ / スーパーオキサイドラジカル / ESR(電子スピン共鳴) / フリーラジカルイメージング / 透析患者 / ピュロマイシンアミノヌクレオシド / 電極法 / 化学発光法 / Griess法 / ESR(電子スピン共鳴法) / NO(一酸化窒素) / サイトカイン / staphylococcal enterotoxin / Vβ陽性細胞 / リンパ球サブセット / コンジェニックマウス / MHCクラスII抗原 / スーパー抗原(superantigen) / MRSA Less

The role of S.aureus bacterial antigen in the pathogenesis of IgA nephritisPrincipal Investigator
- Principal Investigator
  
  KOYAMA Akio
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Ibaraki Prefectural University of Health Science
Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy.Principal Investigator
- Principal Investigator
  
  YAMAGATA Kunihiro, 小山哲夫
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  UNIVERSITY OF TSUKUBA
Involvement of mitochondrial function and mitochondrial DNA mutations in focal segmental glomerulosclresosis
- Principal Investigator
  
  YAMAGATA Kunihiro
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
Development of New Method of Hemodialysis Using Light Shielded Dialyzer and Blood Circuit
- Principal Investigator
  
  NAGASE Sohji
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
Staphylococcus aureus antigens induce IgA-type glomerulonephritis in Balb/c micePrincipal Investigator
- Principal Investigator
  
  KOYAMA Akio
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  INSTITUTE OF CLINICAL MEDICINE UNIVERSITY OF TSUKUBA
Mitochondrial DNA mutations in focal segmental glomerular sclerotic lesions
- Principal Investigator
  
  YAMAGATA Kunihiro
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  UNIVERSITY OF TSUKUBA
STUDIES ON THE MANNER OF T CELL ACTIVATION IN VARIOUS TYPES OF GLOMERULAR DISEASESPrincipal Investigator
- Principal Investigator
  
  KOYAMA Akio
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  UNIVERSITY OF TSUKUBA
The Role of Non-enzymaticically Generated Nitric Oxide on Renal Damages
- Principal Investigator
  
  NAGASE Sohji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
実験的スーパー抗原関連腎炎におけるMHCクラスII抗原の役割
- Principal Investigator
  
  小林正貴
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Experimental pathology
- Research Institution
  University of Tsukuba
Studies on the pathogenesis of glomerulonephritis and vascultitis induced by superantigen.Principal Investigator
- Principal Investigator
  
  KOYAMA Akio
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Institute of Clinical Medicine, University of Tsukuba
スーパー抗原関連腎炎におけるIgA抗体の産生機序についての研究Principal Investigator
- Principal Investigator
  
  小山哲夫
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
ヒトスーパー抗原関連腎炎における腎炎惹起性に及ぼすMHCクラスII抗原の役割Principal Investigator
- Principal Investigator
  
  小山哲夫
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
スーパー抗原関連腎炎の研究-TCRα/β陽性double negative cellの役割-Principal Investigator
- Principal Investigator
  
  小山哲夫
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
ヒト糸球体腎炎発症におけるスーパー抗原の関与についての研究Principal Investigator
- Principal Investigator
  
  小山哲夫
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  University of Tsukuba
Production of vascular permeability factors in minimal change nephrotic syndrome by human T cell hybridoma.
- Principal Investigator
  
  TOJO Shizuo
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  INSTITUTE OF CLINICAL MEDICINE, UNIVERSITY OF TSUKUBA

All 2011 2010 2009 2008 2005 2004 2003 2002 2001 2000 1995 Other

All Journal Article Presentation Book

[Book] コメデイカルのためのCKD慢性腎臓病療養指導マニュアル2010
- Author(s)
  山口直人、鹿野直人、小山哲夫
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-20590960
[Book] 医学書院医学大辞典第2版(腎臓責任編集)2009
- Author(s)
  山口直人、小山哲夫
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20590960
[Book] 医学大辞典第2版2009
- Author(s)
  山口直人、小山哲夫
- Total Pages
  22
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20590960
[Book] 血尿2008
- Author(s)
  山口直人、小山哲夫
- Publisher
  病気と薬南山堂
- Data Source
  KAKENHI-PROJECT-20590960
[Book] 血尿 (病気と薬パーフェクトB00K)2008
- Author(s)
  山口直人, 小山哲夫ら
- Total Pages
  5
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Serum levels of BAFF and APRIL in myeloperoxidase anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis : association with disease activity.2011
- Author(s)
  Nagai M, Koyama A, et al.
- Journal Title
  
  Nephron Clin Pract 118
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Serum levels of BAFF and APRIL in myeloperoxidase anti-neutrophil cytoplasmic autoantibody-associated renal vasculitis : association with disease activity.2011
- Author(s)
  Nagai M/Koyama A
- Journal Title
  
  Nephron Clin Pract
  
  Volume: 118
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Serum ratio of soluble triggering receptor expressed on myeloid cells-1 to creatinine is a useful marker of infectious complications in myelopero xidase-antineutrophil cytoplasmic antibody-associated renal vasculitis.2011
- Author(s)
  Hirayama K/Koyama A
- Journal Title
  
  Nephrol Dial Transplant
  
  Volume: 26 Pages: 868-874
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Serum ration of soluble triggering receptor expressed on myeloid cells-1 to creatinine is a useful marker of infectious complications in myeloperoxidase-antineutrophil cytoplasmic antibody-associated renal vasculitis.2011
- Author(s)
  Hirayama K, Koyama A, et al.
- Journal Title
  
  Nephrol Dial Transplant 26
  
  Pages: 868-874
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Methicillin-resistant staphylococcus-aureus-associated glomerulonephritis on the decline : decreased incidence since the 1990s.2011
- Author(s)
  Usui J/Koyama A
- Journal Title
  
  Clin Exp Nephrol
  
  Volume: 15 Pages: 184-186
- NAID
  10029004988
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Methicillin-resistant staphylococcus-aureus-associated glomerulonephritis on the decline : decreased incidence since the 1990s.2011
- Author(s)
  Usui J, Koyama A, et al.
- Journal Title
  
  Clin Exp Nephrol 15
  
  Pages: 184-186
- NAID
  10029004988
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] A nationwide survey of rapidly progressive glomerulonephritis in Japan : etiology, prognosis and treatment diversity.2009
- Author(s)
  Koyama A, et al
- Journal Title
  
  Clin Exp Nephrol. 13
  
  Pages: 633-650
- NAID
  10027227649
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] PAR2拮抗薬はLPS誘発性腎不全モデルにて炎症、血液凝固、エンドセリンの3系亢進を同時に抑制する2009
- Author(s)
  山口直人、小山哲夫, ら
- Journal Title
  
  日本腎臓学会誌 51
  
  Pages: 360-360
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] a nationwide survey of rapidly progressive glomerulonephritis in Japan : etiology, prognosis and treatment diversity.2009
- Author(s)
  Koyama A, et al.
- Journal Title
  
  Clin Exp Nephrol 13
  
  Pages: 633-650
- NAID
  10027227649
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] successful pregnmancyin a female patient with congenital chloride diarrhea (CLD) and renal impairment.2009
- Author(s)
  Shimizu Y, Koyama A, et al.
- Journal Title
  
  J Nephrol 22
  
  Pages: 809-813
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Renal pathology of ANCA-related vasculitis : proposal for standardization of pathological diagnosis in Japan.2008
- Author(s)
  Joh K, Muso E, Shigematsu H, Koyama A, et al.
- Journal Title
  
  Clin Exp Nephrol 12
  
  Pages: 277-291
- NAID
  10025585377
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Anti-glomerular basement membrane antibody disease in Japan : part of the nationwide rapidly progressive glomerulonephritis suevey in Japan.2008
- Author(s)
  Hirayama K, Yamagata K, Koyama A, et al.
- Journal Title
  
  Clin Exp Nephrol 12
  
  Pages: 339-347
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Renal pathology of ANCA-related vasculitis : proposal for standardization of pathological diagnosis in Japan2008
- Author(s)
  Joh K, Muso E, Shigematsu H, Koyama A, et al
- Journal Title
  
  Clin Exp Nephrol 12
  
  Pages: 277-291
- NAID
  10025585377
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Anti-glomerular basement membrane antibody disease in Japan : part of the nationwide rapidly progressive glomerulonephritis survey in Japan.2008
- Author(s)
  Hirayama K, Yamagata K. Koyama A, et al
- Journal Title
  
  Clin Exp Nephrol 12
  
  Pages: 339-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] a novel apolipoprotein E mutation, Apo E Tsukuba (Arg114 Cys), in lipoprotein glomerulopathy.2008
- Author(s)
  Hagiwara M, Yamagata K, Koyama A, et al.
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 381-384
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] A novel apolipoprote in E mutation, ApoE Tsukuba (Arg 114 Cys), in 1ipoprotein glomerulopathy.2008
- Author(s)
  Hagiwara M, Yamagata K, Koyama, et al
- Journal Title
  
  Nephrol Dial Transplant 23
  
  Pages: 381-384
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590960
[Journal Article] Apheresis for MPO-ANCA-associated RPGN ; Indications and Efficacy : Lessons Learned from Japan Nationwide Survey of RPGN2005
- Author(s)
  Yamagata K, Koyama A et al.
- Journal Title
  
  J Clinical Apheresis 20(In press)
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] 巣状糸球体硬化症の病態生理2004
- Author(s)
  山縣邦弘, 萩原正大, 小山哲夫
- Journal Title
  
  Medical Practice 21(5)
  
  Pages: 729-734
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Treatment with the purine synthesis inhibitor mizoribine for ANCA-associated renal vasculitis.2004
- Author(s)
  Hirayama K, Yamagata K, Koyama A et al.
- Journal Title
  
  Am J Kidney Dis 44(1)
  
  Pages: 57-63
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Staphylococcus aureus cell-envelope antigens are localized in glomeruli from patients with IgA-related nephropathy.2004
- Author(s)
  Koyama A et al.
- Journal Title
  
  Nephrology (Carlton). Dec;9 Suppl 2
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590774
[Journal Article] Age distribution and yearly changes in the incidence of ESRD in Japan.2004
- Author(s)
  Yamagata K, Koyama A. et al.
- Journal Title
  
  American Journal of kidney disease 43(3)
  
  Pages: 433-443
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy.2004
- Author(s)
  Koyama A et al.
- Journal Title
  
  Kidney Int. 66(1)
  
  Pages: 121-32
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590774
[Journal Article] Treatment with the purine synthesis inhibitor mizoribine for ANCA-associated renal vasculitis.2004
- Author(s)
  Hirayama K, Kobayashi M, Hashimoto Y, Usui J, Shimizu Y, Hirayama A, Yoh K, Yamagata K, Nagase S, Nagata M, Koyama A.
- Journal Title
  
  Am J Kidney Dis. 44(1)
  
  Pages: 57-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Age distribution and yearly changes in the incidence of ESRD in Japan.2004
- Author(s)
  Yamagata K, Takahashi H, Suzuki S, Mase K, Hagiwara M, Shimizu Y, Hirayama K, Kobayashi M, Narita M, Koyama A.
- Journal Title
  
  Am J Kidney Dis. 43(3)
  
  Pages: 433-443
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy.2004
- Author(s)
  Koyama A, Sharmin S, Sakurai H, Shimizu Y, Hirayama K, Usui J, Nagata M, Yoh K, Yamagata K, Muro K, Kobayashi M, Ohtani K, Shimizu T, Shimizu T.
- Journal Title
  
  Kidney Int. 66(1)
  
  Pages: 121-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy.2004
- Author(s)
  Koyama A, et al.
- Journal Title
  
  Kidney Int. Jul;66(1)
  
  Pages: 121-132
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590774
[Journal Article] Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy2004
- Author(s)
  Koyama A, Yamagata K et al.
- Journal Title
  
  Kidney International 66・1
  
  Pages: 121-132
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] ミトコンドリア異常と巣状糸球体硬化症2004
- Author(s)
  山縣邦弘, 萩原正大, 小山哲夫
- Journal Title
  
  日本臨床 62(10)
  
  Pages: 1817-1822
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Staphylosoccus aureus cell envelope antigen is a new candi date for the induction of IgA nephropathy2004
- Author(s)
  Koyama A. et al.
- Journal Title
  
  Kidney Int. 66(1)
  
  Pages: 121-132
- Data Source
  KAKENHI-PROJECT-16590774
[Journal Article] Staphylococcus aureus cell-envelope antigens are localized in glomeruli from patients with IgA-related nephropathy.2004
- Author(s)
  Koyama A et al.
- Journal Title
  
  Nephrology(Carlton). 9 Suppl 2
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590774
[Journal Article] Glomerular crescents predominantly express cadherin-catenin complex in pauci-immune-type crescentic glomerulonephritis.2003
- Author(s)
  Usui J, Kanemoto K, Tomari S, Shu Y, Yoh K, Mase K, Hirayama A, Hirayama K, Yamagata K, Nagase S, Kobayashi M, Nitta K, Horita S, Koyama A, Nagata M.
- Journal Title
  
  Histopathology 43
  
  Pages: 173-179
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-15590841
[Journal Article] Predominance of type 2 immune response in idiopathic membranous nephropathy : cytoplasmic cytokine analysis.2002
- Author(s)
  Hirayama K, Ebihara I, Yamamoto S, Kai H, Muro K, Yamagata K, Kobayashi M, Koyama A
- Journal Title
  
  Nephron 91(2)
  
  Pages: 255-61
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Usage of T cell Receptor Variable Segments of the Beta-chain in IgA Nephropathy.2002
- Author(s)
  Muro K, Yamagata K, Kobayashi M, Hirayama K, Koyama A
- Journal Title
  
  Nephron 92
  
  Pages: 56-63
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Th2 predominance at the single-cell level in patients with IgA nephropathy.2001
- Author(s)
  Ebihara I, Hirayama K, Yamamoto S, Muro K, Yamagata K, Koyama A.
- Journal Title
  
  Nephrol Dial Transplant 16
  
  Pages: 1783-9
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Cytokines and T-cell responses in superantigen-related glomerulonephritis following methicillin-resistent Staphylococcus auresus infection.2000
- Author(s)
  K.Yoh, M.Kobayashi, N.Yamaguchi, K.Hirayama, T.Ishizu, S.Kikuchi, S.Iwabuchi, K.Muro, S.Nagase, .Aoyagi, M.Kondoh, K.Takemura, K.Yamagata, A.Koyama.
- Journal Title
  
  Nephrol Dial Transplant. 15
  
  Pages: 1170-1174
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Glomerulonephritis associated with MRSA infection1995
- Author(s)
  Koyama A, Kobayashi M, Yamaguchi N, Yamagata K, Takano K, Nakajima M, Irie F, Goto M, Igarashi M, Iitsuku T, Aoki Y, Sakurai H, Sakurayama N, Fukao K
- Journal Title
  
  A possible role of bacterial superantigen. Kidney Int 47(1)
  
  Pages: 207-216
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Glomerulonephritis associated with MRSA infection : A possible role of bacterial superantigen1995
- Author(s)
  Koyama A, et al.
- Journal Title
  
  Kidney Int 47
  
  Pages: 207-216
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Staphylococcus aureus cell envelope antigen is a new candidate for the development of IgA nephropathy
- Author(s)
  A.Koyama, S.Sharmin, H.Sakurai, Y.Shimizu, K.Hirayama, J.Usui, M.Nagata, K.Yoh, K.Yamagata, K.Muro, M.Kobayashi, K.Ohtani, T.Shimizu, T.Shimizu
- Journal Title
  
  (submission)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Journal Article] Staphylococcus aureus antigens induce IgA-type glomerulonephritis in Balb/c mice.
- Author(s)
  S.Sharmin, Y.Shimizu, K., M.Hagiwara, K.Hirayama, A.KoyamaS.
- Journal Title
  
  (submission)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Presentation] MPO-ANCA関連血管炎におけるB-cell activation factor belonging to the TNF family(BAFF)の検討2010
- Author(s)
  長井美穂、小山哲夫, ら
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] MPO-ANCA関連血管炎におけるB-cell activation factor belonging to the TNF family (BAFF)の検討2010
- Author(s)
  長井美穂/小山哲夫
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸ポートピア国際展示場
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] PAR2拮抗薬はLPS誘発性腎不全モデルにて炎症、血液凝固、エンドセリンの3系亢進を同時に抑制する2009
- Author(s)
  山口直人、小山哲夫, ら
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2009-06-04
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] PAR2拮抗薬はLPS誘発性腎不全モデルにて炎症、血液凝固、エンドセリンの3系統の亢進を同時に抑制する2009
- Author(s)
  山口直人、小山哲夫, ら
- Organizer
  第52回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] Protease-activated receptor 2 blocking peptide counteracts endotoxin-induced inflammation, aberrant vascular homeostasis and coagulation in a rat mode1 of ARF.2009
- Author(s)
  Yamaguchi N, Koyama A, et al.
- Organizer
  第73回日本循環器学会学術総会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2009-03-21
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] LPS誘発性腎不全ラットモデルにおける血管作動性物質の腎組織内における経時的発現2008
- Author(s)
  山口直人、小山哲夫, ら
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] LPS誘発性腎不全ラットモデルにおける血管作動性物質の腎組織内における経時的発現2008
- Author(s)
  山口直人, 小山哲夫ら
- Organizer
  第51回日本腎臓学会学術総会
- Place of Presentation
  福岡国際会議場
- Year and Date
  2008-06-01
- Data Source
  KAKENHI-PROJECT-20590960
[Presentation] Staphylococcus aureus is a new candidate for a pathogen of IgA nephro pathy.2002
- Author(s)
  Koyama A, et al.
- Organizer
  The International Congress of Internal Medicine
- Place of Presentation
  Kyoto Japan
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096
[Presentation] Staphylococcus aureus are localized in glomeruli from patients with IgA-Related Nephropathy stained with mouse monoclonal antibody against Staphylococcus aureus.2001
- Author(s)
  Akio Koyama A, et al
- Organizer
  American Society of Nephrology/International Society of Nephrology World Congress of Nephrology
- Place of Presentation
  San Francisco, CA, USA
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-13671096

1. YAMAGATA Kunihiro (90312850)

# of Collaborated Projects: 6 results

# of Collaborated Products: 16 results
2. 小林正貴 (10195810)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. HIRAYAMA Kouich (10302423)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
4. MURO Kaori (60301082)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. NAGASE Sohji (10189128)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. YAMAGUCHI Naoto (40239900)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
7. KIKUCHI Shuichi (40282355)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. AOYAGI Kazumasa (40114029)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. YANAKA Kiyoyuki (10312307)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HIRAYAMA Aki (20323298)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. YOH Keigyo (90323302)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. SHIMIZU Yoshio (50359577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. TOJO Shizuo (20009103)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. NARITA Mitsuharu (80009472)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 飯塚正 (80251065)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. KOBAYASHI Masaki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 室 PLおり

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results

KOYAMA Akio 小山 哲夫

小山 昭夫 コヤマ アキオ

Research Projects

Research Products

Co-Researchers

The role of S.aureus bacterial antigen in the pathogenesis of IgA nephritisPrincipal Investigator

Principal Investigator

Project Period (FY)

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Staphylococcus aureus cell envelope antigen is a new candidate for the induction of IgA nephropathy.Principal Investigator

Principal Investigator

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Research Institution

Involvement of mitochondrial function and mitochondrial DNA mutations in focal segmental glomerulosclresosis

Principal Investigator

Project Period (FY)

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Research Institution

Development of New Method of Hemodialysis Using Light Shielded Dialyzer and Blood Circuit

Principal Investigator

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Staphylococcus aureus antigens induce IgA-type glomerulonephritis in Balb/c micePrincipal Investigator

Principal Investigator

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Research Institution

Mitochondrial DNA mutations in focal segmental glomerular sclerotic lesions

Principal Investigator

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STUDIES ON THE MANNER OF T CELL ACTIVATION IN VARIOUS TYPES OF GLOMERULAR DISEASESPrincipal Investigator

Principal Investigator

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The Role of Non-enzymaticically Generated Nitric Oxide on Renal Damages

Principal Investigator

Project Period (FY)

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実験的スーパー抗原関連腎炎におけるMHCクラスII抗原の役割

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Studies on the pathogenesis of glomerulonephritis and vascultitis induced by superantigen.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

スーパー抗原関連腎炎におけるIgA抗体の産生機序についての研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ヒトスーパー抗原関連腎炎における腎炎惹起性に及ぼすMHCクラスII抗原の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

スーパー抗原関連腎炎の研究-TCRα/β陽性double negative cellの役割-Principal Investigator

Principal Investigator

Project Period (FY)

KOYAMA Akio 小山哲夫

小山昭夫コヤマアキオ

[Book] 医学大辞典第2版2009