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SAKIYAMA Yukio  崎山 幸雄

ORCIDConnect your ORCID iD *help
Researcher Number 80133734
Other IDs
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Affiliation (based on the past Project Information) *help 2001 – 2003: 北海道大学, 大学院・医学研究科, 寄附講座教員
2001 – 2002: 北海道大学, 大学院・医学研究科, 寄附講座・教員
1999: Hokkaido University, School of Medicine, Visiting Professor, 医学部(寄附講座), 教員
1998: 北大, 医学部, 助教授
1995 – 1996: 北海道大学, 医学部, 助教授 … More
1993: HOKKAIDO UNIVERSITY, MEDICAL HOSPITAL ; LECTURER, 医学部・附属病院, 講師
1992: 北海道大学, 医学部附属病院, 講師
1990: Hokkaido University Medical Hospital, Lecturer, 医学部・附属病院, 講師
1986 – 1990: 北海道大学, 医学部附属病院, 講師
1988: 北海道大学, 医学部付属病院, 講師 Less
Review Section/Research Field
Principal Investigator
Pediatrics
Except Principal Investigator
Pediatrics / Pediatrics / Plastic surgery
Keywords
Principal Investigator
Fibronectin / Blood stem cell / Retrovirus Vector / Gene Therapy / CGD (Chronic Granulomatous Disease) / フィブロネクチン / 血液幹細胞 / レトロウイルスベクター / 遺伝子治療 / 慢性肉芽腫症 … More / EBウイルスDNA / rIL-2 / 慢性活動性EBウイルス感染症 / インタロイキン2 / EBV遺伝子 / EBNA-2A / 慢性活動性EBウイルス感染 … More
Except Principal Investigator
Flow cytometry / SAC / SNP / WASP / Wiskott-Aldrich syndrome / Mixed Chimera / WASP分子 / フローサイトメトリー / 血液幹細胞移植 / Wiskott-Aldrich症候群 / Wnt pathway / AIE-75 / CD4^+8^+ thymocyte / T cell antigen receptor / human thymocyte / BSA discontinuous density gradient / TcR遺伝子 / CD4^+CD8^+細胞 / 2H4+胸腺細胞 / CD4+8+胸腺細胞 / T細胞レセプタ-遺伝子 / BSA不連続濃度勾配法 / CD4^+8^+細胞 / T細胞抗原レセプタ- / ヒト胸腺細胞 / BSA不連続慎濃度勾配法 / pre B cell / EBV / IL-2 / Primary hypogammaglobulinemia / recombinant IL-2 / Ig産生能 / CVI / B細胞 / μ鎖mRNA / preB細胞 / EBウイルス樹立株 / IL2 / 無(低)ガンマグロブリン血症 / intermolecular conformational change / 分子内構造変化 / TCOF1 gene / Genome / Lhx8 gene / Cleft lip and palate / TCOF1遺伝子 / ゲノム解析 / Lhx8遺伝子 / 唇顎口蓋裂 / Mixed chimera / Hematopoietic stem cell transplantation / yeast / PDZ domain / enteropathy / 自己免疫性腸炎 / 大腸癌 / 蛋白間相互作用 / Two-hybridアッセイ / PDZドメイン蛋白 / MCC / 酵母 / PDZドメイン / 自己免疫性大腸症 / MOLECULAR GENETIC ANALYSIS / CHRONIC GRANULOMATOUS DISEASE / 点突然変異 / 遺伝子学的解析 / 好中球チトクローム重鎖遺伝子 / 遺伝子解析 / 慢性肉芽腫症 Less
  • Research Projects

    (11 results)
  • Research Products

    (5 results)
  • Co-Researchers

    (18 People)
  •  Structural and functional studies of WASP molecule in cellular basis

    • Principal Investigator
      ARIGA Tadashi
    • Project Period (FY)
      2003 – 2004
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Mixed chimera status in patients with Wiskott-Aldrich syndrome (WAS) after hematopoietic stem cell transplantation ; evaluation by flow cytometric analysis of intracellular WAS protein expression.

    • Principal Investigator
      ARIGA Tadashi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Genomic Analysis of Non Syndromic Cleft Lip with or without Cleft Palete

    • Principal Investigator
      KAWASHIMA Kunihiro
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Plastic surgery
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  慢性肉芽腫症に対する遺伝子治療の基礎的研究Principal Investigator

    • Principal Investigator
      崎山 幸雄
    • Project Period (FY)
      1998
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Hokkaido University
  •  Molecular analysis of novel PDZ domain-containing gene encoding autoantigen of autoimmune enteropathy

    • Principal Investigator
      HOSOKAWA Masuo, 外木 秀文
    • Project Period (FY)
      1998 – 1999
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  Basic Research on Gene Therapy for Chronic Granulomatous DiseasePrincipal Investigator

    • Principal Investigator
      SAKIYAMA Yukio
    • Project Period (FY)
      1995 – 1996
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      Hokkaido Unviersity
  •  MOLECULAR GENETIC ANALYSIS OF CHRONIC GRANULOMATOUS DISEASE.

    • Principal Investigator
      MATSUMOTO Shuzo
    • Project Period (FY)
      1992 – 1993
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      HOKKAIDO UNIVERSITY
  •  慣性活動性EBウイルス感染症における病態解析と治療法の検討Principal Investigator

    • Principal Investigator
      崎山 幸雄
    • Project Period (FY)
      1989
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Hokkaido University
  •  慢性活動性EBウイルス感染症における病態解析とリンホカインによる治療の検討Principal Investigator

    • Principal Investigator
      崎山 幸雄
    • Project Period (FY)
      1988
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Pediatrics
    • Research Institution
      Hokkaido University
  •  Analysis of Mechanisms in Maturation of Human T Cells in the Thymus and Characterization of Various Factors Affecting Those Process.

    • Principal Investigator
      MATSUMOTO Shuzo
    • Project Period (FY)
      1988 – 1990
    • Research Category
      Grant-in-Aid for General Scientific Research (A)
    • Research Field
      Pediatrics
    • Research Institution
      Hokkaido University
  •  ANALYSIS OF B CELL ACTIVATION AND DIFFERENTIATION IN PRIMARY HYPOGAMMAGLOBULINEMIA.

    • Principal Investigator
      MATSUMOTO Shuzo
    • Project Period (FY)
      1986 – 1987
    • Research Category
      Grant-in-Aid for General Scientific Research (B)
    • Research Field
      Pediatrics
    • Research Institution
      HOKKAIDO UNIVERSITY

All 2005 2004

All Journal Article

  • [Journal Article] Molecular analysis of nonsyndromic preaxial polydactyly ; preaxial polydactyly type-IV and preaxial polydactyly type-I.2005

    • Author(s)
      Fujioka H, Ariga T, Horiuchi K, Otsu M, Igawa H, Kawashima K, Sugihara T, Sakiyama Y.
    • Journal Title

      Clin Genet 67

      Pages: 429-433

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591076
  • [Journal Article] Mutational Analysis of the TCOF1 Gene in 11 Japanese Patients with Treacher Collins Syndrome and mechanism of mutagenesis.2005

    • Author(s)
      Horiuchi K, Ariga T, Fujioka H, Kawashima K, Yamamoto Y, Ikawa H, Sakiyama Y
    • Journal Title

      Am J Med Genet 134A

      Pages: 363-367

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591076
  • [Journal Article] Confirming or excluding the diagnosis of Wiskott-Aldrich syndrome in children with thrombocytopenia of an unknown etiology.2004

    • Author(s)
      Ariga T, Nakajima M, Sakiyama Y.et al.
    • Journal Title

      J Ped Hem One 26

      Pages: 435-440

    • Description
      「研究成果報告書概要(和文)」より
    • Data Source
      KAKENHI-PROJECT-15591076
  • [Journal Article] Treacher Collins syndrome with craniosynostosis, choanal atresia and esophageal regurgitation caused by a novel nonsense mutation in the TCOF1.2004

    • Author(s)
      Horiuchi K, Ariga T, Fujioka H, Kawashima K, Yamamoto Y, Ikawa H, Sakiyama Y, Sugihara T.
    • Journal Title

      Am J Med Genet 128A

      Pages: 173-175

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591076
  • [Journal Article] Confirming or excluding the diagnosis of Wiskott-Aldrich syndrome in children with thrombocytopenia of an unknown etiology.2004

    • Author(s)
      Ariga T, Nakajima M, Yoshida J, Yamato K, Nagatoshi Y, Yanai F, Caviles AP, Nelson DL, Sakiyama Y.
    • Journal Title

      J Ped Hem Onc 26

      Pages: 435-440

    • Description
      「研究成果報告書概要(欧文)」より
    • Data Source
      KAKENHI-PROJECT-15591076
  • 1.  MATSUMOTO Shuzo (80000933)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 2.  HOSOKAWA Masuo (20001901)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 3.  ARIGA Tadashi (60322806)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 5 results
  • 4.  TAKEKOSHI Yasuo (50109427)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 5.  ISHIKAWA Yorikazu (40159710)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  KAJII Naofumi (20194730)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  OKANO Motohiko (50261300)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  ODAGAWA Yasuhisa (50292024)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  MORIUCHI Tetsuya (20174394)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  KOBAYASHI Ryouji (30301899)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 11.  KAWASHIMA Kunihiro (30281801)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 12.  IGAWA Hiroharu (10232159)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 13.  SUGIHARA Tsuneki (20002157)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 14.  ODA Atsusi (50255436)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 15.  TOGASHI Takehiro (70001930)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 16.  外木 秀文 (50281803)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 17.  大川 正人 (10168875)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 18.  SEKIDO Mitsuru
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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