SHINDO Heisaburo 神藤平三郎

… Alternative Names

神藤平三郎シンドウヘイサブロウ

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Researcher Number	80138966
Other IDs
Affiliation (based on the past Project Information) *help	2009: 独立行政法人農業生物資源研究所, タンパク質機能研究ユニット, 外来研究員 2007: 独立行政法人農業・食品産業技術総合研究機構, 植物科学研究領域タンパク質機能研究ユニット, 特別研究員 1999 – 2005: Tokyo University of Pharmacy and Life Science, School of Pharmacy, Professor, 薬学部, 教授 1994 – 1998: 東京薬科大学, 薬学部, 助教授 1990 – 1992: 東京薬科大学, 薬学部, 助教授 1986 – 1987: Tokyo College of Pharmacy, 薬学部, 助教授 1986: 東京薬大, 薬学部, 助教授
Review Section/Research Field	Principal Investigator Biological Sciences / 生物物性学 / Physical pharmacy / Physical pharmacy Except Principal Investigator Functional biochemistry / Structural biochemistry / 生物物性学
Keywords	Principal Investigator NMR / ヌクレオソーム / 転写抑制機構 / クロマチン / Ume6p / CD / Siz1 / PIASy / PIAS1 / Helix dipole … More / Charge interaction / CD-melting / 熱測定 / Rme1p / Dynamics of DNA / Structure of bulge loop / Structure of hairpin loop / cro repressor / HU protein / Structure and function of tRNA / Structures of DNA / Hu-DNA複合体 / Croリプレッサー / ヘアピンループ / 制限酵素 / tRNA / DNA / X線回析 / DNAの分子運動 / バルジループの構造 / Cro蛋白質ヘアピンループの構造 / Hu蛋白質 / tRNAの構造と機能 / DNA構造の多形 / conformational change / oligonucleotide / Structure and Dynamics of DNA / ^2H NMR / ^1H NMR / ^<31>P NMR / 重水素NMR / 分子運動 / オリゴ核酸 / DNA繊維 / 化学シフト / オリゴヌクレオチド / プロトンNMR / 運動 / DNAの構造 / transcription factor Lef-1 / NMR structure / Tumor seppresor p53 / SUMO ligase / DNA結合蛋白質 / SAPドメイン / SUMOリガーゼ / 転写因子Lef-1 HMG / NMR構造 / 癌抑制因子p53 / SUMO リガーゼ / Guanidine hydrochloride / Urea denaturation / Point mutant / Yhhp protein / N-キャッピング / 点変異体 / YhhP蛋白質 / 塩酸グアニジン / 尿素 / CD melting / 塩酸グアニジン変性 / 尿素変性 / Point mutants / YhhP / Chemical modifications / Nucleosome / Chromatin / Thermal property / Triplet repeat / Structural morphorism / DNA triplex / 熱安定性 / トリプレットリピート / 化学修飾 / トリプレットリート / 構造多形 / 三重鎖DNA / non-βDNA / ヒストンHH01 / Rme1 / Yhhp / SNF2 / SWI / ブロモドメイン / 構造 / DNA結合タンパク質 / Zm-finger / Zn-finger … More Except Principal Investigator NMR / DNA / X線結晶解析 / 立体構造 / タンパク質 / 塩基配列 / 核磁気共鳴(NMR) / コンホメーション / 核酸ドメイン / 構造生物学 / 分子認識 / 蛋白質 / Myb / がん遺伝子産物 / Mybタンパク質 / 高次構造 / Antisense / Computer simulation / Thermodynamics / Triplex DNA / アンチセンス / 計算機シミュレーション / 熱力学 / 三重鎖DNA / Molecular Biology / RNA-binding Proteins / DNA-binding Proteins / Transcription Factors / X-ray Crystallography / Structural Biology / X線結晶 / 転写因子 / 構造生理学 / ヒストン認識 / DNA結合 / SUMOリガーゼ / SUMO化翻訳後修飾 / 生物物理 / DNA結合ドメイン / がン遺伝子産物 / DNA給合ドメイン / 転写調節 / DNA結合蛋白質 / OmpR / DNAの湾曲 / ラマン分光 / DNA結合タンパク質 Less

Structures and Functions of the N-terminal Domains of SUMO Ligase PIAS/Siz Family
- Principal Investigator
  
  YAMAZAKI Toshimasa
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Structural biochemistry
- Research Institution
  National Institute of Agrobiological Sciences
Domain strcture of SUMO ligase PIAS1 ant ispecific interaction of its target protein p53Principal Investigator
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Sciences
Sequence effects of new N-capping motif CPxP on structural stability of YhhP proteinPrincipal Investigator
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
転写不活性因子-クロマチンの相互作用ネットワークの構造基盤Principal Investigator
- Principal Investigator
  
  神藤平三郎
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
転写不活性因子-クロマチンの相互作用ネットワークの構造基盤Principal Investigator
- Principal Investigator
  
  神藤平三郎
- Project Period (FY)
  2000
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
転写不活性因子-クロマチンの相互作用ネットワークの構造基盤Principal Investigator
- Principal Investigator
  
  神藤平三郎
- Project Period (FY)
  1999
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
転写不活性因子ークロマチンの相互作用ネットワークの構造基盤Principal Investigator
- Principal Investigator
  
  神藤平三郎
- Project Period (FY)
  1998
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas (A)
- Review Section
  
  Biological Sciences
- Research Institution
  Tokyo University of Pharmacy and Life Science
Structural morphorism of DNA triplexes and triplet repeat sequencesPrincipal Investigator
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Physical pharmacy
- Research Institution
  Tokyo University of Pharmacy and Life Science
Mechanism of Triplex DNA Formation ; And Its Application to Antisense
- Principal Investigator
  
  SARAI Akinori
- Project Period (FY)
  1997 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Functional biochemistry
- Research Institution
  RIKEN Insutitute
Roles of Protein Structures on the DNA Recognition
- Principal Investigator
  
  NISHIMURA Yoshifumi
- Project Period (FY)
  1994 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
蛋白質が認識するDNA構造
- Principal Investigator
  
  西村善文
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
遺伝子調節機構の立体構造とダイナミクスの研究調査
- Principal Investigator
  
  西村善文
- Project Period (FY)
  1992
- Research Category
  
  Grant-in-Aid for Co-operative Research (B)
- Research Field
  
  生物物性学
- Research Institution
  Yokohama City University
蛋白質が認識するDNA構造
- Principal Investigator
  
  西村善文
- Project Period (FY)
  1991
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
蛋白質が認識するDNA構造
- Principal Investigator
  
  NISHIMURA Yoshifumi
- Project Period (FY)
  1990
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Yokohama City University
Versatality of Nucleic Acid Structure and its recognitionPrincipal Investigator
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  1986 – 1987
- Research Category
  
  Grant-in-Aid for Co-operative Research (A)
- Research Field
  
  生物物性学
- Research Institution
  Tokyo College of Pharmacy
核酸ドメインのコンホメーション解析
- Principal Investigator
  
  大井龍夫
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
核酸ドメインのコンホメーション解析
- Principal Investigator
  
  大井龍夫
- Project Period (FY)
  1985 – 1987
- Research Category
  
  Grant-in-Aid for Special Project Research
- Research Institution
  Kyoto University
Base sequence dependence of the structure and dynamics, and thermodynamic properties of oligonucleotidesPrincipal Investigator
- Principal Investigator
  
  SHINDO Heisaburo
- Project Period (FY)
  1984 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  生物物性学
- Research Institution
  Tokyo College of Pharmacy

All 2009 2007 2005 2004

All Journal Article Presentation

[Journal Article] Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases from Saccharomyces cerecisiae and Oryza sativa2009
- Author(s)
  Suzuki R, Shindo H, Tase A, Kikuchi Y, Shimizu M, Yamazaki T
- Journal Title
  
  Proteins 75(2)
  
  Pages: 336-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570115
[Journal Article] Solution structures and DNA binding properties of the N-terminal SAP domains of SUMO E3 ligases from Saccharomyces cervisiae and Oryza sativa.2009
- Author(s)
  Suzuki R, Shindo H, Tase A, Kikuchi Y, Shimizu M, Yamazaki T
- Journal Title
  
  PROTEINS 75(2)
  
  Pages: 336-347
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19570115
[Journal Article] Mitochondria-specific RNA-modifying Enzymes Respongible for the Biosynthesis of the Wobble Base in Mitochondrial tRNAs2005
- Author(s)
  N.Umeda, T.Suzuki, M.Yukawa, Y.Ohya, H.Shindo, K.Watanabe, T.Suzuki
- Journal Title
  
  J.Biol.Chem. 280
  
  Pages: 1613-1624
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590034
[Journal Article] Mitochondria-specific RNA-modifying Enzymes Respongible for the Biosynthesis of the Wobble Base in Mitochondrial tRNAs2005
- Author(s)
  N.Umeda, T.Suzuki, M.Yukawa, Y.Ohya, H.Shindo, K.Watanabe, T.Suzuki
- Journal Title
  
  J. Biol. Chem 280
  
  Pages: 1613-1624
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590034
[Journal Article] Hydrogen-bond patterns in the hydration structure of a protein2005
- Author(s)
  T.Yokomizo, M.Nakasako, T.Yamazaki, H.Shindo, J.Higo
- Journal Title
  
  Chem.Phys.Lett. 401
  
  Pages: 332-336
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590034
[Journal Article] NMR structure of the N-termnal domain of SUMO ligase PIAS1 and its interaction with tumor supressor p53 and A/T-rich DNA oligomers2004
- Author(s)
  S.Okubo, F.Hara, Y.Tsuchida, S.Shimotakahara, S.Suzuki, H.Hatanaka, S.Yokoyama, H.Tanaka, H.Yasuda, H.Shindo
- Journal Title
  
  J.Biol.Chem. 279(30)
  
  Pages: 31455-31461
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590034
[Presentation] Structure and function of the N-terminal domains of SUMO ligase Siz/PIAS family2007
- Author(s)
  Yamazaki T, Suzuki R, Tase A, Nishiuchi Y, Shindo H
- Organizer
  The 4th International Peptide Symposium
- Place of Presentation
  Cairns, Australia
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-19570115
[Presentation] N-terminal SAP and PHD-finger domains of SUMO ligase Siz1 from Oryza sativa are essential for recognition of methylated histone as well as DNA binding2007
- Author(s)
  Yamazaki T, Suzuki R, Tase A, Nishiuchi Y, Shindo H
- Organizer
  第47回NMR討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-12
- Data Source
  KAKENHI-PROJECT-19570115
[Presentation] NMR structures and self-sumoylation of the N-terminal SAP domains of SUMO ligase PIAS/Siz family2007
- Author(s)
  Suzuki R, Shindo H, Tase A Yamazaki T
- Organizer
  第47回NMR討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-19570115
[Presentation] Structure and function of the N-terminal domains of SUMO ligase Siz/PIAS family2007
- Author(s)
  Yamazaki T, Suzuki R, Tase A, Nishiuchi Y, Shindo H
- Organizer
  The 4^<th> International Peptide Symposium
- Place of Presentation
  Cairns,Australia
- Year and Date
  2007-10-24
- Data Source
  KAKENHI-PROJECT-19570115
[Presentation] NMR structures and self-sumoylation of the N-terminal SAP domains of SUMO PIAS/Siz family2007
- Author(s)
  Suzuki R, Shindo H, Tase A, Yamazaki T
- Organizer
  第47回NMR討論会
- Place of Presentation
  札幌
- Year and Date
  2007-09-13
- Data Source
  KAKENHI-PROJECT-19570115

1. KYOGOKU Yoshimasa (90012632)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
2. NISHIMURA Yoshifumi (70107390)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. 水野猛 (10174038)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
4. 上杉晴一 (70028851)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
5. 清水光弘 (80231364)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. NISHIKAWA Kazuya (60109262)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
7. YOKOYAMA Shigeyuki (00159229)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. HAKOSHIMA Toshio (00164773)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. 甲斐荘正恒 (20137029)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. 藤井敏 (10107104)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 磯野克己 (70011640)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. YAMAZAKI Toshimasa (40360458)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
13. SHIRAKIHARA Yasuo (20150287)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. YAMAZAKI Toshio (60273710)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. ISHII Shunsuke (00124785)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. SARAI Akinori (20221286)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. TORIGOE Hidetaka (80227678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. YOKOYAMA Kazunari (80182707)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. GEKKO Kinihiko (10023467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 陶山明 (90163063)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 今川正良 (20136823)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 大井龍夫 (00027012)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 大井龍夫 (00027004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. PICHIERRI Fabio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. PICHIERRI Fa

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SHINDO Heisaburo 神藤 平三郎

神藤 平三郎 シンドウ ヘイサブロウ

Research Projects

Research Products

Co-Researchers

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Domain strcture of SUMO ligase PIAS1 ant ispecific interaction of its target protein p53Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Sequence effects of new N-capping motif CPxP on structural stability of YhhP proteinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

転写不活性因子-クロマチンの相互作用ネットワークの構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写不活性因子-クロマチンの相互作用ネットワークの構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

転写不活性因子-クロマチンの相互作用ネットワークの構造基盤Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

転写不活性因子ークロマチンの相互作用ネットワークの構造基盤Principal Investigator

Principal Investigator

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Research Category

Review Section

Research Institution

Structural morphorism of DNA triplexes and triplet repeat sequencesPrincipal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Principal Investigator

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Versatality of Nucleic Acid Structure and its recognitionPrincipal Investigator

Principal Investigator

SHINDO Heisaburo 神藤平三郎

神藤平三郎シンドウヘイサブロウ