YAMANO Shigeru 山野茂

Researcher Number	80140755
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2014: 福岡大学, 薬学部, 教授 2008: 福岡大学, 薬学部, 教授 2007: 福岡大学, 薬学部, 准教授 2006: 福岡大学, 薬学部, 助教授
Review Section/Research Field	Except Principal Investigator Pain science / Hygiene / Environmental pharmacy
Keywords	Except Principal Investigator チオールケミストリー / ケミカルバイオロジー / ディーゼル排出微粒子 / 多環芳香族炭化水素キノン類 / 大気汚染物質 / 共有結合 / 親電子性物質 / モルヒネ6位脱水素酵素 / μ-受容体 / 耐性発現機構 … More / ドッキングシミュレーション / ラット17β-HSD type 6 / ラット17β-HSD type 2 / インターナリゼーション / HEK293細胞 / μ-受容体-GFP融合タンパク質 / エピモルヒネ / モルヒネ / 17β-ﾋﾄﾞﾛｷｼｽﾃﾛｲﾄﾞ脱水素酵素 / ヒト尿中代謝物 / モルヒノン / 新電子性物質 / ナフタレン / 大気汚染 / キノン系化合物 Less

The role of morphinone in the tolerance development to morphine
- Principal Investigator
  
  NARIMATSU SHIZUO
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Pain science
- Research Institution
  Okayama University
Naphthalens that covalently bind to macromolecules contaminated in the atmosphere in southern California
- Principal Investigator
  
  KUMAGAI Yoshito
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Environmental pharmacy
- Research Institution
  University of Tsukuba
ディーゼル排出微粒子中に存在する未知の親電子性物質の新規探索法の開発
- Principal Investigator
  
  熊谷嘉人
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Hygiene
- Research Institution
  University of Tsukuba

All 2008 2007 2006 Other

All Journal Article Presentation

[Journal Article] Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells2008
- Author(s)
  Taguchi K, Shimada M, Fujii S,umi D, Pan XQ,Yamano S, Nishiyama T, Hiratsuka A, Yamamoto M, Cho AK, Froines JR, Kumagai Y
- Journal Title
  
  Free Radical Biology & Medicine 2008 44
  
  Pages: 1945-1655
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18406003
[Journal Article] An approach to evaluate two-electron reduction of 9,10-phenanthraquinone and redox activity of the hydroquinone associated with oxidative stress2007
- Author(s)
  Taguchi K, Fujii S, Yamano S, Cho AK, Kamisuki S, Nakai Y, Sugawara F, Froines JR, Kumagai Y
- Journal Title
  
  Free Radical Biology & Medicine 2007 43
  
  Pages: 789-799
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18406003
[Journal Article] 1,2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea.2006
- Author(s)
  Kikuno S, Taguchi K, Iwamoto N, Yamano S, Cho AK, Froines JR, Kumagai Y.
- Journal Title
  
  Toxicology and Applied Pharmacology. 210
  
  Pages: 47-54
- Data Source
  KAKENHI-PROJECT-18406003
[Journal Article] Inhibition of Endothelial Nitric Oxide Synthase Activity and Suppression of Endothelium-Dependent Vasorelaxation by 1, 2-Naphthoquinone, a Component of Diesel Exhaust Particles.2006
- Author(s)
  Sun Y, Taguchi K, Sumi D, Yamano S, Kumagai Y.
- Journal Title
  
  Arch Toxicol. 80
  
  Pages: 280-285
- Data Source
  KAKENHI-PROJECT-18659167
[Journal Article] Inhibition of Endothelial Nitric Oxide Synthase Activity and Suppression of Endothelium-Dependent Vasorelaxation by 1,2-Naphthoquinone, a Component of Diesel Exhaust Particles.2006
- Author(s)
  Sun Y, Taguchi K, Sumi D, Yamano S, Kumagai Y.
- Journal Title
  
  Arch Toxicol. 80
  
  Pages: 280-285
- Data Source
  KAKENHI-PROJECT-18406003
[Journal Article] 1, 2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea.2006
- Author(s)
  Kikuno S, Taguchi K, Iwamoto N, Yamano S, Cho AK, Froines JR, Kumagai Y.
- Journal Title
  
  Toxicology and Applied Pharmacology. 210
  
  Pages: 47-54
- Data Source
  KAKENHI-PROJECT-18659167
[Presentation] ラット 17β-Hydroxysteroid dehydrogenase type 2による Morphine及び Epimorphine の立体選択的代謝反応の機構解明
- Author(s)
  増田和文, 加藤久登, 齋藤啓太, 片岡洋行, 熊本卓哉, 舟橋達也, 田邊知孝, 喜多秀樹, 石田隆, 山野茂, 松本考弘, 上島将幹, 成松鎭雄
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24659289
[Presentation] ラット 17β-Hydroxysteroid dehydrogenase type 2 及び type 6によるMorphine及び Epimorphine の立体選択的代謝反応の速度論的解析
- Author(s)
  成松鎭雄, 松本考弘,上島将幹,増田和文,加藤久登, 齋藤啓太,片岡洋行,熊本卓哉, 舟橋達也, 田邊知孝, 喜多秀樹, 石田隆, 山野茂
- Organizer
  日本薬学会第135年会
- Place of Presentation
  神戸市
- Year and Date
  2015-03-26 – 2015-03-28
- Data Source
  KAKENHI-PROJECT-24659289

1. TAKANO Hirohisa (60281698)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
2. KUMAGAI Yoshito (00250100)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
3. SUMI Daigo (30400683)

# of Collaborated Projects: 2 results

# of Collaborated Products: 2 results
4. NARIMATSU SHIZUO (20113037)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. MATSUOKA Junji (30332795)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. HANIOKA Nobumitsu (70228518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. KITA Hideki (60341450)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. KUMAMOTO Takuya (50292678)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
9. FUNAHASHI Tatsuya (60343646)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. TANABE Tomotaka (60532786)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. MASUDA Kazufumi (00243486)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
12. KATAOKA Hiroyuki (80127555)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
13. SAITO Keita (30454854)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
14. MATSUNAGA Hisashi (10569156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. IMAMURA Makio

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

YAMANO Shigeru 山野 茂

Research Projects

Research Products

Co-Researchers

The role of morphinone in the tolerance development to morphine

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Naphthalens that covalently bind to macromolecules contaminated in the atmosphere in southern California

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

ディーゼル排出微粒子中に存在する未知の親電子性物質の新規探索法の開発

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Redox cycling of 9,10-phenanthraquinone to cause oxidative stress is terminated through its monoglucuronide conjugation in human pulmonary epithelial A549 cells2008

Author(s)

Journal Title

Data Source

[Journal Article] An approach to evaluate two-electron reduction of 9,10-phenanthraquinone and redox activity of the hydroquinone associated with oxidative stress2007

Author(s)

Journal Title

Data Source

[Journal Article] 1,2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea.2006

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of Endothelial Nitric Oxide Synthase Activity and Suppression of Endothelium-Dependent Vasorelaxation by 1, 2-Naphthoquinone, a Component of Diesel Exhaust Particles.2006

Author(s)

Journal Title

Data Source

[Journal Article] Inhibition of Endothelial Nitric Oxide Synthase Activity and Suppression of Endothelium-Dependent Vasorelaxation by 1,2-Naphthoquinone, a Component of Diesel Exhaust Particles.2006

Author(s)

Journal Title

Data Source

[Journal Article] 1, 2-Naphthoquinone activates vanilloid receptor 1 through increased protein tyrosine phosphorylation, leading to contraction of guinea pig trachea.2006

Author(s)

Journal Title

Data Source

[Presentation] ラット 17β-Hydroxysteroid dehydrogenase type 2による Morphine及び Epimorphine の立体選択的代謝反応の機構解明

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ラット 17β-Hydroxysteroid dehydrogenase type 2 及び type 6によるMorphine及び Epimorphine の立体選択的代謝反応の速度論的解析

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

YAMANO Shigeru 山野茂