HAYASHI Koichi 林晃一

… Alternative Names

HAYASHI Kohichi

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Researcher Number	80164937
Other IDs
Affiliation (based on the past Project Information) *help	2015 – 2016: 東京歯科大学, 歯学部, 教授 2014: 慶應義塾大学, 医学部, 准教授 2010 – 2012: 慶應義塾大学, 医学部, 准教授 2008: Keio University, 医学部, 准教授 2006 – 2007: 慶應義塾大学, 医学部, 講師 … More 2004 – 2005: 慶應義塾大学, 医学部, 専任講師 1995 – 2001: 慶應義塾大学, 医学部, 講師 1999: Medical Engineering, Keio University, Assistant Professor 1996: Keio University, School of Medicine, Associate Professor, 医学部, 講師 1986: The Keio University School of Medicine, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine / Circulatory organs internal medicine Except Principal Investigator Kidney internal medicine / 内科学一般 / Biomedical engineering/Biological material science / Kidney internal medicine
Keywords	Principal Investigator 輸出細動脈 / 輸入細動脈 / atRA / eNOS / DDAH / ADMA / 慢性腎不全 / efferent arterioles / afferent arterioles / 高血圧 … More / 尿細管 / 加齢 / 慢性腎臓病 / 腎障害 / coronary endothelial dysfunction / chronic kidney disease / ATRA / 冠動脈内皮機能障害 / 慢性腎障害 / chronic renal failure / proteinuria / hypertension / Rho kinase / 腎微小循環 / RhoA / 蛋白尿 / Rhoキナーゼ / renal hemodynamics / kidney / angiotensin receptor antagonists / angiotensin converting enzyme inhibitors / アンジオテンシン変換酵素阻害薬 / 腎血行動態 / 腎臓 / アンジオテンシン受容体拮抗薬 / アンジオテンシン変化酵素阻害薬 / シスプラチン / ミトコンドリア / 酸化ストレス / 近位尿細管 / 糖尿病 / Sirt / 長寿遺伝子 / 腎委縮 / FOXO / アポトーシス / 腎尿細管細胞 / カロリー制限 / SIRT / エネルギー代謝 / Sirt1 / 耐糖能異常 / 糸球体高血圧 / 血管内皮 / インシュリン / 肥満 … More Except Principal Investigator Rho / Rhoキナーゼ / 3T3L1-fibroblast / C57BL / Hypertension / Nitric oxide / Protein kinase C / Intracellular calcium / Pressure natriuresis curve / 高血圧 / メタボリックシンドローム / The remaining kidney / Sodium / Hemi-nephrectomy / 腎機能 / 残存腎 / ナトリウム / 片腎摘 / 6J mice / Adipocytes / Rho kinase / Chronic kidney disease / Metabolic syndrome / トランスジェニックマウス / 腎機能障害 / 6Jマウス / 脂肪細胞 / 慢性腎臓病 / メタボリック症候群 / Vascular Pulsation / Niobium microsphere / High-speed CCD Intravital microscope / Coronary Slosh Phenomenon / Subendocardial Arterioles / ACE阻害剤 / 内皮非依存性血管拡張反応 / 内皮依存性血管拡張反応 / 心筋虚血 / 心内膜側冠細動脈 / 冠予備 / 高血圧肥大心 / 血管拍動性 / niobium microsphere / 高速度CCD生体顕微鏡 / 冠動脈slosh現象 / 心内膜側細動脈 / microscopy / dexamethasone / renal hemodynamics / efferent arterioles / afferent arterioles / kidney / angiotensin / chymase / キマ-ゼ / アンジオテンシン受容体 / 腎血行動態 / 輸出細動脈 / 輸入細動脈 / 腎臓 / アンジオテンシン / キマーゼ / Dahl salt-sensitive rats / Salt sensitivity / Postmenopause / ダールラット / エストロゲン / 血小板 / 圧利尿反応 / 卵巣摘出術 / 細胞内カルシウム代謝 / 更年期高血圧 / 筋小胞体Caポンプ / NO / Dahl食塩感受性ラット / 食塩感受性 / 更年期 / 近位尿細管 / 肥満関連腎症 / HIF / PHD / 虚血 / Cell Cycle / PHD2 / RhoA / cell cycle / proximal tubule / p27 / mDia / rho-kinase / 尿細管細胞肥大 / 脂肪腎臓連関 / ミネラルコルチコイド受容体 / 脂肪組織 / 肥満 / アルドステロン Less

Pathophysiology of non-diabetic/obesity induced renal injuries
- Principal Investigator
  
  Tokuyama Hirobumi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Pathophysiological relevance of visceral fat and kidneys in obesity-induced renal injury
- Principal Investigator
  
  TOKUYAMA Hirobumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Therapeutic strategy for chronic kidney disease and hypertension based on time/metabolism regulation.Principal Investigator
- Principal Investigator
  
  HAYASHI Koichi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Anti-aging therapy against chronic kidney diseasePrincipal Investigator
- Principal Investigator
  
  HAYASHI Koichi
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
The role of Rho/Rho kinase pathway in the metabolic syndrome-associated renal insufficiency
- Principal Investigator
  
  WAKINO Shu
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
The investigation of inducing factors of cardiovascular events in early stage of chronic kidney diseasePrincipal Investigator
- Principal Investigator
  
  HAYASHI Koichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Keio University
Investigation on the role of Rho A in the progression of renal injuryPrincipal Investigator
- Principal Investigator
  
  HAYASHI Koichi
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Clinial Relevance of Novel Angiotensin II Generation Pathway within the KidneyPrincipal Investigator
- Principal Investigator
  
  HAYASHI Koichi
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Clinical Relevance of Novel Angiotensin II Generation Pathway within the Kidney
- Principal Investigator
  
  SARUTA Takao
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Evaluation of time sequential changes in subendocardial arteioles in the hypertensive hypertrophic canine heart by using needle-lens CCD intravital microscope
- Principal Investigator
  
  KAJIYA Fumihiko
- Project Period (FY)
  1997 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Biomedical engineering/Biological material science
- Research Institution
  Kawasaki Medical School
インシュリン非依存性糖尿病におけ腎障害進展阻止機構の検討Principal Investigator
- Principal Investigator
  
  林晃一
- Project Period (FY)
  1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Keio University
Genetic Background and Underlying Mechanism in the Development of Postmenopausal Hypertension
- Principal Investigator
  
  SARUTA Takao
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  Keio University
STUDIES ON THE INCIDENCE AND MECHANISM OF HYPERTENSION IN HEMI-NEPHRECTOMIZED SUBJECTS.
- Principal Investigator
  
  SARUTA Takao
- Project Period (FY)
  1985 – 1986
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  The Keio University

All 2016 2015 2014 2013 2012 2011 2010 2008 2007 2006

All Journal Article Presentation Book

[Book] 血圧・血行力学関連、ADMA.動脈硬化症の新しい診断・治療標的2012
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22590915
[Book] 血圧・血行力学関連、ADMA。動脈硬化症の新しい診断・治療標的。倉林正彦監修、山岸昌一編集2012
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22590915
[Book] 第VII章、高血圧のoptimalmedical treatment-Ca拮抗薬の機序とその位置づけ。成功に導くPCI治療戦略。中村正人、編集2011
- Author(s)
  林晃一
- Data Source
  KAKENHI-PROJECT-22590915
[Book] CKDステージとCa拮抗薬の使い分け。降圧薬-俺流処方。伊藤裕編集2011
- Author(s)
  林晃一
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-22590915
[Book] 輸入・輸出細動脈。高血圧ナビゲーター(第3版)、熊谷裕生、小室一成、堀内正嗣、森下竜一編2011
- Author(s)
  林晃一
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules2016
- Author(s)
  Futatsugi K, Tokuyama H, Shibata S, Naitoh M, Kanda T, Minakuchi H, Yamaguchi S, Hayashi K, Minamishima YA, Yanagita M, Wakino S, Itoh H
- Journal Title
  
  Sci Rep
  
  Volume: 6 Issue: 1 Pages: 365331-12
- DOI
  10.1038/srep36533
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16H04723, KAKENHI-PROJECT-26461236, KAKENHI-PROJECT-26670163, KAKENHI-PROJECT-16H05315
[Journal Article] Communication from Tubular Epithelial Cells to Podocytes through Sirt1 and Nicotinic Acid Metabolism.2016
- Author(s)
  Hasegawa K, Wakino S, Sakamaki Y, Muraoka H, Umino H, Minakuchi H, Yoshifuji A, Naitoh M, Shinozuka K, Futatsugi K, Urai H, Kanda T, Tokuyama H, Hayashi K, Itoh H.
- Journal Title
  
  Curr Hypertens Rev. Curr Hypertens Rev.
  
  Volume: 12 (2) Pages: 95-104
- Data Source
  KAKENHI-PROJECT-26461236
[Journal Article] Communication from Tubular Epithelial Cells to Podocytes through Sirt1 and Nicotinic Acid Metabolism.2016
- Author(s)
  Hasegawa K, Wakino S, Sakamaki Y, Muraoka H, Umino H, Minakuchi H, Yoshifuji A, Naitoh M, Shinozuka K, Futatsugi K, Urai H, Kanda T, Tokuyama H, Hayashi K, Itoh H.
- Journal Title
  
  Curr Hypertens Rev.
  
  Volume: *
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461236
[Journal Article] Renin-angiotensin blockade resets podocyte epigenome through Kruppel-like Factor 4 and attenuates proteinuria.2015
- Author(s)
  Hayashi K, Sasamura H, Nakamura M, Sakamaki Y, Azegami T, Oguchi H, Tokuyama H, Wakino S, Hayashi K, Itoh H
- Journal Title
  
  Kidney Int
  
  Volume: 88(4) Issue: 4 Pages: 745-753
- DOI
  10.1038/ki.2015.178
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26461236, KAKENHI-PROJECT-25860687
[Journal Article] The role of adipose tissue asymmetric dimethylarginine/dimethylarginine dimethylaminohydrolase pathway in adipose tissue phenotype and metabolic abnormalities in subtotally nephrectomized rats.2015
- Author(s)
  Minakuchi H, Wakino S, Hosoya K, Sueyasu K, Hasegawa K, Shinozuka K, Yoshifuji A, Futatsugi K, Komatsu M, Kanda T, Tokuyama H, Hayashi K, Itoh H.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 31(3) Issue: 3 Pages: 413-423
- DOI
  10.1093/ndt/gfv367
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26461236
[Journal Article] Insulin resistance in chronic kidney disease is ameliorated by spironolactone in rats and humans.2014
- Author(s)
  Hosoya K, Minakuchi H, Wakino S (Corresponding Author), Fujimura K, Hasegawa K, Komatsu M, Yoshifuji A, Futatsugi K, Shinozuka K, Washida N, Kanda T, Tokuyama H, Hayashi K, Itoh H.
- Journal Title
  
  Kidney Int
  
  Volume: 87 Issue: 4 Pages: 749-60
- DOI
  10.1038/ki.2014.348
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25293197, KAKENHI-PROJECT-26461236
[Journal Article] The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1-dependent mechanism in mice.2013
- Author(s)
  Hasegawa K, Wakino S, Kimoto M, Minakuchi H, Fujimura K, Hosoya K, Komatsu M, Kaneko Y, Kanda T, Tokuyama H, Hayashi K, Itoh H.
- Journal Title
  
  FASEB J.
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590898
[Journal Article] The hydrolase DDAH2 enhances pancreatic insulin secretion by transcriptional regulation of secretagogin through a Sirt1-dependent mechanism in mice.2013
- Author(s)
  Hasegawa K, Wakino S, Kimoto M, Minakuchi H, Fujimura K, Hosoya K, Komatsu M, Kaneko Y, Kanda T, Tokuyama H, Hayashi K, Itoh H
- Journal Title
  
  FASEB Journal
  
  Volume: (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Role of Mineralocorticoid receptor/Rho/Rho-kinase pathway in Obesity-Related Renal Injury.2012
- Author(s)
  Tokuyama H, Wakino S, Hara Y, Washida N, Fujimura K, Hosoya K, Yoshioka K, Hasegawa K, Minakuchi H, Homma K, Hayashi K, Itoh H.
- Journal Title
  
  Int J Obes (Lond)
  
  Volume: 36(8) Pages: 1062-71
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590898
[Journal Article] ROCK阻害薬はFOXO3a活性を上昇させ血管内皮細胞の増殖、遊走、酸化ストレス耐性能を低下させる2012
- Author(s)
  本間康一郎、脇野修、林晃一、堀進吾、伊藤裕
- Journal Title
  
  未病と抗老化
  
  Volume: 21(6) Pages: 86-89
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Triglyceride-rich lipoproteins in chronic kidney disease patients undergoing maintenance hemodialysis treatment.2012
- Author(s)
  Homma K, Homma Y, Yamaguchi S, Shiina S, Wakino S, Hayashi K, Itoh H
- Journal Title
  
  International Journal of Clinical Practice
  
  Volume: 66(4) Pages: 394-398
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Role of mineralocorticoid receptor/Rho/ Rho-kinase pathway in obesity-related renal injury.2012
- Author(s)
  Tokuyama H, Wakino S, Hara Y, Washida N, Fujimura K, Hosoya K, Yoshioka K, Hasegawa K, Minakuchi H, Homma K, Hayashi K, Itoh H
- Journal Title
  
  International Journal of Obesity Research
  
  Volume: 36(8) Pages: 1062-1071
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] CKDの病態とその管理の実際2011
- Author(s)
  林晃一
- Journal Title
  
  内科
  
  Volume: 107(2) Pages: 203-209
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] 腎微小循環とCaチャネルサブタイプ2011
- Author(s)
  本間康一郎、林晃一、菅野直希、山口慎太郎、脇野修、堀進吾、伊藤裕
- Journal Title
  
  脈管学
  
  Volume: 51(1) Pages: 133-138
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis.2011
- Author(s)
  Washida N, Wakino S, Tonozuka Y, Homma K, Tokuyama H, Hara Y, Hasegawa K, Minakuchi H, Fujimura K, Hosoya K, Hayashi K, Itoh H.
- Journal Title
  
  Nephrol Dial Transplant.
  
  Volume: 26(9) Pages: 2770-2779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590898
[Journal Article] JATOSサブ解析2011
- Author(s)
  林晃一
- Journal Title
  
  循環器内科
  
  Volume: 70(4) Pages: 400-406
- NAID
  40019059902
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Rho and Rho-kinase activation in adipocytes contributes to a vicious cycle in obesity that may involve mechanical stretch2011
- Author(s)
  Hara Y, Wakino S, Tanabe y, Saito M, Tokuyama H, Washida N, Tatematsu S, Yoshioka K, Homma K, Hasegawa K, Minakuchi H, Fujimura K, Hosoya K, Hayashi K, Nakayama K, Itoh H
- Journal Title
  
  Science Signaling
  
  Volume: 4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] L-/T-type Ca channel blockers for kidney protection: ready for sophisticated use of Ca channel blockers.2011
- Author(s)
  Hayashi K
- Journal Title
  
  Hypertension Research
  
  Volume: 34(8) Pages: 910-912
- NAID
  10030275396
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] 慢性腎臓病とレニン・アンジオテンシン・アルドステロン系2011
- Author(s)
  林晃一
- Journal Title
  
  循環器内科
  
  Volume: 69(1) Pages: 68-74
- NAID
  40018726155
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis.2011
- Author(s)
  Washida N, Wakino S, Tonozuka Y, Homma K, Tokuyama H, Hara Y, Hasegawa K, Minakuchi H, Fujimura K, Hosoya K, Hayashi K, Itoh H
- Journal Title
  
  Nephrology Dialysis &Transplantation
  
  Volume: 26 (9) Pages: 2770-2779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis2011
- Author(s)
  Washida N, Wakino S, Tonozuka Y, Homma K, Tokuyama H, Hara Y, Hasegawa K, Minakuchi H, Fujimura K Hosoya K, Hayashi K, Itoh H
- Journal Title
  
  Nephrology Dialysis & Transplantation
  
  Volume: 26 Issue: 9 Pages: 2770-2779
- DOI
  10.1093/ndt/gfr012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Rho and Rho-kinase activation in adipocytes contributes to a vicious cycle in obesity that may involve mechanical stretch.2011
- Author(s)
  Hara Y, Wakino S, Tanabe y, Saito M, Tokuyama H, Washida N, Tatematsu S, Yoshioka K, Homma K, Hasegawa K, Minakuchi H, Fujimura K, Hosoya K, Hayashi K, Nakayama K, Itoh H
- Journal Title
  
  Science Signaling
  
  Volume: 4(157)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Rho and Rho-Kinase Activity in Adipocytes Contributes to a Vicious Cycle in Obesity That May Involve Mechanical Stretch.2011
- Author(s)
  Hara Y, Wakino S, Tanabe Y, Saito M, Tokuyama H, Washida N, Tatematsu S, Yoshioka K, Homma K, Hasegawa K, Minakuchi H, Fujimura K, Hosoya K, Hayashi K, Nakayama K, Itoh H.
- Journal Title
  
  Sci Signal
  
  Volume: 25;4(157)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590898
[Journal Article] T-type Ca channel blockade as a determinant of kidney protection.2010
- Author(s)
  Hayashi K, Homma K, Wakino S, Tokuyama H, Sugano N, Saruta T, Itoh H
- Journal Title
  
  The Keio Journal of Medicine
  
  Volume: 59 (3) Pages: 84-95
- NAID
  10029470053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] 高齢者腎疾患と高血圧(腎硬化症を含む)2010
- Author(s)
  林晃一、脇野修、徳山博文
- Journal Title
  
  Geriatric Medicine
  
  Volume: 48 (8) Pages: 1041-1045
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] カルシウム拮抗薬2010
- Author(s)
  林晃一
- Journal Title
  
  Life style Medicine
  
  Volume: 4(4) Pages: 61-66
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Impact of renal function on cardiovascular events in elderly hypertensive patients treated with efonidipine.2010
- Author(s)
  Hayashi K, Saruta T, Goto Y, Ishii M
- Journal Title
  
  Hypertension Research
  
  Volume: 33(11) Pages: 1211-1220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] カルシウム拮抗薬-Caチャネルサブタイプと腎保護作用2010
- Author(s)
  林晃一
- Journal Title
  
  Therapeutic Research
  
  Volume: 31(9) Pages: 1271-1277
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Brachial-ankle pulse wave velocity predicts silent cerebrovascular diseases in patients with end-stage renal diseases.2010
- Author(s)
  Washida N, Wakino S, Hayashi K, Kuwahara T, Itoh H
- Journal Title
  
  Journal of Atherosclerosis & Thrombosis
  
  Volume: 17(2) Pages: 165-172
- NAID
  130004444405
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] Kidney-specific overexpression of Sirt1 protects against acute kidney injury by retaining peroxisome function.2010
- Author(s)
  Hasegawa K, Wakino S, Yoshioka K, Tatematsu S, Hara Y, Minakuchi H, Sueyasu K, Washida N, Tokuyama H, Tzukerman M, Skorecki K, Hayashi K, Itoh H
- Journal Title
  
  Journal of Biological Chemistry
  
  Volume: 285(17) Pages: 13045-13056
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22590915
[Journal Article] T-type calcium channel blockade as a therapeutic strategyagainst renal injury in rats with subtotal nephrectomy.2008
- Author(s)
  Sugano N, Hayashi K, et al.
- Journal Title
  
  Kidney International 73
  
  Pages: 826-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] T-type calcium channel blockade as a therapeutic strategy against renal injury in rats with subtotal nephrectomy2008
- Author(s)
  Sugano N, Wakino S, Kanda T, Tatematsu S, Homma K, Yoshioka K, Hasegawa K, HaraY, Suetsugu Y, Yoshizawa T, Hara Y, Utsunomiya Y, Tokudome G, Hosoya T, Saruta T, Hayashi K
- Journal Title
  
  Kidney International 73(7)
  
  Pages: 826-834
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Renal cytochrome P450 as a determinant of impaired natriuresis by PPARγ ligands in ovariectomized obese rats.2008
- Author(s)
  Yoshioka K, Hayashi K, et al.
- Journal Title
  
  Obesity 16
  
  Pages: 965-971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Cardiovascular disease, chronic kidney disease, and type 2 diabetes mellitus : proceeding with caution at a dangerous intersection.2008
- Author(s)
  Kanda T, Hayashi K, et al.
- Journal Title
  
  Journal of the American Society of Nephrology 19
  
  Pages: 4-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] ADMA and Renal and Heart Disease2008
- Author(s)
  Hayashi, K, Wakino, S
- Journal Title
  
  Heart View 12(3)
  
  Pages: 288-291
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] 【腎障害と心疾患心腎相関を識る】識る心・腎疾患と憩撚2008
- Author(s)
  林晃一、立松覚、脇野修, 他
- Journal Title
  
  Heart View 12巻3号
  
  Pages: 288-291
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Cardiovascular disease, chronic kidney disease, and type 2 diabetes mellitus : proceeding with caution at a dangerous intersection2008
- Author(s)
  Kanda T, Wakino S, Hayashi K, Plutzky J
- Journal Title
  
  Journal of the American Society of Nephrology 19(1)
  
  Pages: 4-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Sirt1 protects againstoxidative stress-induced renal tubularapoptosis by bidirectional regulation of catalase expression2008
- Author(s)
  Hasegawa K, Wakino S, Tatematsu S, Yoshioka K, Hara Y, Minakuchi H, Tokuyama H, Washida N, Homma K,Hayashi K, Itoh H
- Journal Title
  
  Biochemical & Biophysical Research Communications 372(1)
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Renal cytochrome P450 as a determinant of impaired natriuresis by PPARγ ligands in ovariectomized obese rats2008
- Author(s)
  Yoshioka K, Wakino S, Homma K, Kanda T,Tatematsu S, Hasegawa K, Sugano N, Ito O, Omata K, Saruta T, Hayashi K
- Journal Title
  
  Obesity 16(5)
  
  Pages: 965-971
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Sirtl protects against oxidative stress-induced renal tubular apoptosis by bidirectional regulation of catalase expression.2008
- Author(s)
  Hasegawa K, Hayashi K, et al.
- Journal Title
  
  Biochemical & Biophysical Research Communications 372
  
  Pages: 51-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] 【腎障害と心疾患心腎相関を識る】識る心、腎疾患とADMA2008
- Author(s)
  林晃一、立松覚、脇野修, 他
- Journal Title
  
  Heart View 12巻3号
  
  Pages: 288-291
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Role of dimethylarginine in vascular injury in transgenic mice overexpressing dimethylarginine dimethylaminohydrolase 22007
- Author(s)
  Hasegawa K, Hayashi K, et. al.
- Journal Title
  
  Circulation Research 101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] CKDの治療法を個別的に考える CKDとカルシウム拮抗薬(CCB)2007
- Author(s)
  林晃一、菅野直希、脇野修
- Journal Title
  
  内科 100巻1号
  
  Pages: 94-98
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] 【腎臓から心血管障害を考える】メタボリックシンドロームと心腎連関2007
- Author(s)
  脇野修、立松覚、林晃一、伊藤裕
- Journal Title
  
  分子心血管病 8巻5号
  
  Pages: 440-448
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Role of nitric oxide producing and degrading pathways in coronary endothelial dysfunction in chronic kidney disease2007
- Author(s)
  Tatematsu S, Hayashi K, et. al.
- Journal Title
  
  Journal of the American Society of Nephrology 18
  
  Pages: 741-749
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Renal Events and RENAAL Study2007
- Author(s)
  Hayashi, K, Wakino, S
- Journal Title
  
  Diagnosis and Laboratory 684
  
  Pages: 41-44
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Ca2+ channel subtypes and pharmacology in the kidney2007
- Author(s)
  Hayashi, K, Wakino, S, et. al.
- Journal Title
  
  Circ Res. 100(3)
  
  Pages: 342-353
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Internal Medicine, Chronic Kidney Disease and Calcium Channel Blocker2007
- Author(s)
  Hayashi, K, Sugano, N, Wakino, S
- Journal Title
  
  Internal Medicine 100(1)
  
  Pages: 94-98
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] 【ARBのエビデンスを日本の臨床に活かす】腎イベント RENAAL試験2007
- Author(s)
  林晃一、脇野修
- Journal Title
  
  実験治療 684号
  
  Pages: 41-44
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] 【腎臓から心血管障害を考える】メタボリックシンドロームと心腎連関2007
- Author(s)
  脇野修、立松覚、林晃一、伊藤裕
- Journal Title
  
  分子心血管病 8巻5号
  
  Pages: 440-448
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Ca^<2+> channel subtypes and pharmacology in the kidney2007
- Author(s)
  Hayashi K, et. al.
- Journal Title
  
  Circulation Research 100
  
  Pages: 342-343
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19590963
[Journal Article] Ca2+channel subtypes and pharmacology in the kidney2007
- Author(s)
  Hayashi K, wakino S, et. al.
- Journal Title
  
  Circ Res. 100(3)
  
  Pages: 342-353
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Ca2+ channel subtypes and pharmacology in the kidney2007
- Author(s)
  Hayashi K, Wakino S, et. al.
- Journal Title
  
  Circ Res 100(3)
  
  Pages: 342-353
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Metabolic Syndrome and Cardio-Renal Interaction2007
- Author(s)
  Wakino, S, Tatematsu, S, Hayashi, K, Itoh, H
- Journal Title
  
  Molecular Cardiovascular Medicine 8(5)
  
  Pages: 440-448
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Aldosterone Blockers and Treatment of Hypertension2006
- Author(s)
  Hayashi, K, Wakino, S
- Journal Title
  
  Journal of Blood Pressure 13(7)
  
  Pages: 751-755
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Molecular mechanisms and therapeutic strategies of chronic renal injury : role of rho-kinase in the development of renal injury2006
- Author(s)
  Hayashi, K, Wakino, S, et. al.
- Journal Title
  
  J Pharmacol Sci 100(1)
  
  Pages: 29-33
- NAID
  10018240989
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Primary malignant hepatic pheochromocytoma with negative adrenal scintigraphy2006
- Author(s)
  Homma K, Hayashi K, Wakino S, et. al.
- Journal Title
  
  Hypertens Res 29(7)
  
  Pages: 551-554
- NAID
  10018346964
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] 【腎、尿路疾患の診療指針'06】高血圧内分泌性高血圧(Cushing症候群、原発性アルドステロン症、褐色細胞腫、その他の内分泌性高血圧症)2006
- Author(s)
  林晃一, 脇野修, 柴田洋孝
- Journal Title
  
  腎と透析 61巻増刊
  
  Pages: 393-398
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Endocrine Hypertension2006
- Author(s)
  Hayashi, K, Wakino, S, Shibata, H
- Journal Title
  
  Kidney and Dialysis 61
  
  Pages: 393-398
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Primary malignant hepatic pheochromocytoma with negative adrenal scintigraphy2006
- Author(s)
  Homma, K, Hayashim K, Wakino, S, et. al.
- Journal Title
  
  Hypertens Res. 29(7)
  
  Pages: 551-554
- NAID
  10018346964
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] 【リスクホルモンとしてのアルドステロン】アルドステロン受容体拮抗薬と高血圧治療2006
- Author(s)
  林晃一, 脇野修
- Journal Title
  
  血圧 13巻7号
  
  Pages: 751-755
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Journal Article] Molecular mechanisms and therapeutic strategies of chronic renal injury:role of rho-kinase in the development of renal injury2006
- Author(s)
  Hayashi K, Wakino S, et. al.
- Journal Title
  
  J Pharmacol Sci 100(1)
  
  Pages: 29-33
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 腎不全に伴う脂肪組織機能障害と異所性脂肪沈着2015
- Author(s)
  水口斉、脇野修、細谷幸司、藤村慶子、吉藤歩、長谷川一宏、神田武志、徳山博文、林晃一、伊藤裕
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京（東京都千代田区）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26461236
[Presentation] 非糖尿病・肥満関連腎症の病態生理- 相対的虚血による尿細管間質障害2015
- Author(s)
  二木功治、徳山博文、内藤真紀子、脇野修、林晃一、伊藤裕
- Organizer
  第19回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26461236
[Presentation] 非糖尿病・肥満関連腎症の病態生理―相対的虚血による尿細管間質障害．2015
- Author(s)
  二木功治、徳山博文、内藤真規子、林晃一、脇野修、伊藤裕
- Organizer
  第58回日本腎臓学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26461236
[Presentation] 肥満関連腎症における近位尿細管Rho/Rhoキナーゼの役割2015
- Author(s)
  内藤真規子、徳山博文、二木功治、林晃一、脇野修、伊藤裕
- Organizer
  第88回日本内分泌学会学術総会
- Place of Presentation
  ホテルニューオータニ東京（東京都千代田区）
- Year and Date
  2015-04-23
- Data Source
  KAKENHI-PROJECT-26461236
[Presentation] 肥満関連腎症の病態生理の解明2015
- Author(s)
  内藤真紀子、徳山博文、二木功治、脇野修、林晃一、伊藤裕
- Organizer
  第19回日本心血管内分泌代謝学会学術総会
- Place of Presentation
  神戸国際会議場（兵庫県神戸市）
- Year and Date
  2015-12-10
- Data Source
  KAKENHI-PROJECT-26461236
[Presentation] 肥満関連腎症における近位尿細管Rho/Rhoキナーゼの役割2015
- Author(s)
  内藤真規子、徳山博文、二木功治、林晃一、脇野修、伊藤裕
- Organizer
  第58回日本腎臓学術総会
- Place of Presentation
  名古屋国際会議場（愛知県名古屋市）
- Year and Date
  2015-06-05
- Data Source
  KAKENHI-PROJECT-26461236
[Presentation] 肥満関連腎症の病態生理の解明-組織学的変化の新たな知見2013
- Author(s)
  徳山博文、脇野修、二木功治、神田武志鷲田直輝、鷲田直輝、長谷川一宏、水口斉、藤村慶子、林晃一、伊藤裕
- Organizer
  第56回日本腎臓学会
- Place of Presentation
  東京
- Year and Date
  2013-05-11
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] 肥満関連腎症における脂肪腎臓連関の病態生理の解明2012
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直輝、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第16回日本心血管内分泌代謝学会総会
- Place of Presentation
  東京
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 肥満関連腎症における脂肪腎臓連関の病態生理の解明2012
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直樹長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第16回日本心血管内分泌代謝学会
- Place of Presentation
  東京.
- Year and Date
  2012-11-23
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] 近位尿細管Sirt1はペルオキシソームストレスを抑制する-Conditional Tg, KOマウスの解析-2012
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第55回日本腎臓学会総会、シンポジウム
- Place of Presentation
  横浜
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 尿細管特異的Sirt1欠損マウスは、液性因子NMN低下を介し糖尿病性腎症のアルブミン尿が増悪する-2012
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第55回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] アンジオテンシンIIによる腎障害に対するGhrelinの腎保護効果2012
- Author(s)
  藤村慶子、脇野修、林晃一、伊藤裕
- Organizer
  第55回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] アンジオテンシンIIによる腎障害に対するGhrelinの腎保護効果2012
- Author(s)
  脇野修、藤村慶子、水口斉、長谷川一宏、徳山博文、林晃一、伊藤裕
- Organizer
  第35回日本高血圧学会総会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] Ca拮抗薬の薬剤間差-T型、L型、N型Ca拮抗薬の腎保護作用-2012
- Author(s)
  林晃一
- Organizer
  第35回日本高血圧学会総会、シンポジウム
- Place of Presentation
  名古屋
- Year and Date
  2012-09-20
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] Sirt1は、Dnmt1を介したepigenetic制御で、糖尿病性腎症のclaudin-1 CpGメチル化を促進し、アルブミン尿を低下させる2012
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第55回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-01
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 肥満関連腎症における脂肪腎臓連関の病態生理の解明.2012
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直樹、長谷川一宏、水口斉、藤村慶子、本間康一郎、小松素明、金子友香、林晃一、伊藤裕.
- Organizer
  第35回日本高血圧学会
- Place of Presentation
  名古屋
- Year and Date
  2012-09-21
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] 肥満関連腎症の病態生理における脂肪腎臓連関の重要性.2012
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直樹、長谷川一宏、水口斉、二木功治、本間康一郎、林晃一、伊藤裕
- Organizer
  第55回日本腎臓学会学術総会
- Place of Presentation
  横浜
- Year and Date
  2012-06-02
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] 超音波パルスドプラーによる腎動脈血流速度と腎臓内血管抵抗の臨床的意義についての検討2011
- Author(s)
  藤村慶子、脇野修、林晃一、伊藤裕
- Organizer
  第54回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-16
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 尿細管Sirt1過剰発現マウスは、糖尿病性腎症のclaudin-1異所性高発現を改善し、アルブミン尿を低下させる2011
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第54回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 尿細管Sirt1過剰発現マウスは、糖尿病性腎症のclaudin-1異所性高発現を改善し、アルブミン尿を低下させる2011
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第54回日本腎臓学会総会
- Place of Presentation
  パシフィコ横浜(神奈川)
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 肥満関連腎症における腹部脂肪組織除去の有用性2011
- Author(s)
  徳山博文、脇野修、神田武志、原義和、鷲田直樹、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第54回日本腎臓学会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] アンジオテンシンIIによる腎老化作用に対するGhrelinの腎保護効果2011
- Author(s)
  藤村慶子、脇野修、水口斉、長谷川一宏、徳山博文、林晃一、伊藤裕
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 肥満関連腎症における脂肪腎臓連関の病態生理の解明2011
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直輝、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第34回日本高血圧学会総会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 尿細管特異的Sirt1過剰発現マウスを用いた腎障害発症機序についての解析。2011
- Author(s)
  脇野修、長谷川一宏、坂巻祐介、久保田英司、林晃一、伊藤裕
- Organizer
  第34回日本高血圧学会総会、高血圧関連疾患モデル学会合同シンポジウム
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-22
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 肥満関連腎症における脂肪腎臓連関の病態生理の解明2011
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直樹、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第15回日本心血管内分泌代謝学会
- Place of Presentation
  大阪.
- Year and Date
  2011-11-25
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] 肥満関連腎症における脂肪腎臓連関の病態生理の解明2011
- Author(s)
  徳山博文、脇野修、神田武志、鷲田直樹、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第34回日本高血圧学会
- Place of Presentation
  宇都宮
- Year and Date
  2011-10-21
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] アンジオテンシンIIによる腎老化作用に対するGhrelinの腎保護効果2011
- Author(s)
  藤村慶子、脇野修、林晃一、伊藤裕
- Organizer
  第54回日本腎臓学会総会
- Place of Presentation
  横浜
- Year and Date
  2011-06-15
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] アンジオテンシンIIによる腎老化作用に対するGhrelinの腎保護効果2011
- Author(s)
  藤村慶子、脇野修、水口斉、原義和、長谷川一宏、徳山博文、林晃一、伊藤裕
- Organizer
  第84回日本内分泌学会総会
- Place of Presentation
  神戸国際会議場(兵庫)
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] アルドステロン/Rho/Rhoキナーゼ経路の肥満関連腎症における役割2010
- Author(s)
  徳山博文、脇野修、原義和、鷲田直樹、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第33回日本高血圧学会
- Place of Presentation
  福岡
- Year and Date
  2010-10-16
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] アルドステロン(Ald)/Rho/Rhoキナーゼ経路の肥満関連腎症における意義2010
- Author(s)
  徳山博文、脇野修、原義和、鷲田直樹、長谷川一宏、水口斉、本間康一郎、林晃一、伊藤裕
- Organizer
  第53回日本腎臓学会学術総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-17
- Data Source
  KAKENHI-PROJECT-22590898
[Presentation] 長寿遺伝子Sirt1近位尿細管特異的過剰発現マウスはペルオキシダーゼを保護し、急性腎障害を抑制する2010
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第53回日本腎臓学会総会
- Place of Presentation
  神戸
- Year and Date
  2010-06-16
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] アルドステロン(Ald)/Rho/Rhoキナーゼ経路の肥満関連腎症における役割2010
- Author(s)
  徳山博文、脇野修、原義和、鷲田直樹、長谷川一宏、水口斉、藤村慶子、本間康一郎、林晃一、伊藤裕
- Organizer
  第33回日本高血圧学会総会
- Place of Presentation
  福岡
- Year and Date
  2010-10-17
- Data Source
  KAKENHI-PROJECT-22590915
[Presentation] 尿細管SIRTのアポトーシス抑制作用2008
- Author(s)
  長谷川一宏、脇野修、林晃一、伊藤裕
- Organizer
  第51回日本腎臓学会
- Place of Presentation
  福岡
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 性腎臓病におけるインスリン抵抗性と尿細管障害2008
- Author(s)
  水口斉、脇野修、林晃一、伊藤裕
- Organizer
  第51回日本腎臓学会
- Place of Presentation
  福岡
- Year and Date
  2008-05-31
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 尿細管SIRT1はFoxO3a核内移行・カタラーゼ活性化を介し、アポトーシスを抑制する。2008
- Author(s)
  長谷川一宏、脇野修、木本眞順美、立松覚、吉岡恭子、本間康一郎、原義和、林晃一、伊藤裕
- Organizer
  第12回日本心血管内分泌代謝学会
- Place of Presentation
  熊本
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] ADMA分解酵素DDAH2は高脂肪食による膵頭内UCP2上昇を阻止し、膵インスリン分泌を亢進する-トランスジェニックマウスを用いた検討-2008
- Author(s)
  長谷川一宏、脇野修、立松覚、徳山博文、原義和、水口斉、林晃一、伊藤裕
- Organizer
  第31回日本高血圧学会総会
- Place of Presentation
  札幌
- Year and Date
  2008-10-11
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 血管内皮細胞機能におけるRho/ROCK系の意義と転写因子FOXOの関与の検討2008
- Author(s)
  本間康一郎、徳山博文、脇野修、立松覚、吉岡恭子、長谷川一宏、原義和、林晃一、伊藤裕
- Organizer
  第12回日本心血管内分泌代謝学会
- Place of Presentation
  熊本
- Year and Date
  2008-11-29
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 尿細管SIRT 1 はFox03a核内移行・カタラーゼ活性化を介し、アポトーシスを抑制する。2008
- Author(s)
  長谷川一宏, 林晃一, 他
- Organizer
  第12回日本心血管内分泌代謝学会
- Place of Presentation
  熊本
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 慢性腎臓病における冠動脈内皮機能障害2007
- Author(s)
  立松覚、林晃一、脇野修, 他
- Organizer
  第28回日本炎症・再生医学会
- Place of Presentation
  東京
- Year and Date
  2007-08-02
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 慢性腎臓病におけるmethylarginineの役割 ADMAとSDMA2007
- Author(s)
  立松覚、林晃一、脇野修, 他
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Year and Date
  2007-05-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] The Role of Methylarginine in Chronic Kidney Disease-ADMA and SDMA2007
- Author(s)
  Tatematsu, S, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 50th Annual JSN Meeting
- Place of Presentation
  Hamamatsu
- Year and Date
  2007-05-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] ADMA分解酵素DDAH2のインスリン抵抗性に及ぼす影響-トランスジェニックマウスを用いた検討2007
- Author(s)
  長谷川一宏、脇野修、木本眞順美、立松覚、吉岡恭子、本間康一郎、原義和、林晃一、伊藤裕
- Organizer
  第11回日本心血管内分泌代謝学会
- Place of Presentation
  東京
- Year and Date
  2007-11-17
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 慢性腎臓病におけるmethytarginineの役割ADMAとSDMA2007
- Author(s)
  立松覚、林晃一、脇野修, 他
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Year and Date
  2007-05-25
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 腎障害時の心血管障害におけるT型Caチャネルとの関連2007
- Author(s)
  菅野直希、林晃一、脇野修、末次靖子、吉澤威勇、原洋一郎、徳留悟朗、細谷龍男
- Organizer
  第30回日本高血圧学会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] ADMAによる冠動脈硬化作用およびDDAH2の血管保護作用-DDAH2トランスジェニックマウスを用いた検討-2007
- Author(s)
  長谷川一宏、脇野修、木本真順美、立松覚、吉岡恭子、本間康一郎、原義和、林晃一、伊藤裕
- Organizer
  第30回日本高血圧学会総会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-09
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] The role of ADMA in the Coronary Endothelial Dysfunction in Chronic Kidney Disease2007
- Author(s)
  Tatematsu, S, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 39th General Meeting and Annual Scientific Meeting of Japanese Atherosclerosis Society
- Place of Presentation
  Osaka
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] The Relationship between Cardiovascular Disease and T-type Calcium Channel2007
- Author(s)
  Sugano, N, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 30th Annual Scientific Meeting of the Japanese Society of Hypertension
- Place of Presentation
  Okinawa
- Year and Date
  2007-10-25
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] The Therapeutic Significances of the Blocking of T-type Calcium Channel in Cardiovascular Damages in the Renal Insufficiency2007
- Author(s)
  Sugano, N, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 50th Annual JSN Meeting
- Place of Presentation
  Hamamatsu
- Year and Date
  2007-05-28
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 虚血再還流腎症におけるPPARγのforkhead transcription factorを介する作用2007
- Author(s)
  吉岡恭子、林晃一, 他
- Organizer
  日本腎臓学会
- Place of Presentation
  浜松
- Year and Date
  2007-05-27
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 虚血再還流腎症におけるPPARγのForkhead transcription factorを介する作用2007
- Author(s)
  脇野修、吉岡恭子、長谷川一宏、立松覚、原義和、窪田直人、林晃一、伊藤裕
- Organizer
  第7回日本抗加齢医学会総会
- Place of Presentation
  京都
- Year and Date
  2007-07-20
- Data Source
  KAKENHI-PROJECT-19590963
[Presentation] 慢性腎臓病における冠動脈内皮機能障害2007
- Author(s)
  立松覚、林晃一、脇野修, 他
- Organizer
  第28回日本炎症、再生医学会
- Place of Presentation
  東京
- Year and Date
  2007-08-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 腎障害時の心血管障害におけるT型Caチャネル(TCC)抑制の意義2007
- Author(s)
  菅野直希、林晃一、脇野修, 他
- Organizer
  第50回日本腎臓学会学術総会
- Place of Presentation
  浜松
- Year and Date
  2007-05-28
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 腎障害時の心血管病変とT型Caチャネルとの関連2007
- Author(s)
  菅野直希、林晃一、脇野修, 他
- Organizer
  第30回日本高血圧学会
- Place of Presentation
  沖縄
- Year and Date
  2007-10-25
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 慢性腎臓病(CKD)と動脈硬化慢性腎臓病に伴う冠動脈内皮機能障害におけるADMAの役割2007
- Author(s)
  立松覚、林晃一、脇野修, 他
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-13
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] 慢性腎臓病(CKD)と動脈硬化慢性腎臓病に伴う冠動脈内皮機能障害におけるADMAの役割2007
- Author(s)
  立松覚、林晃一、脇野修, 他
- Organizer
  第39回日本動脈硬化学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-07-14
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] The Coronary Endothelia Dysfunction in Chronic Kidney Disease2007
- Author(s)
  Tatematsu, S, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 28th Annual Meeting of the Japanese Society of Inflammation and Regeneration
- Place of Presentation
  Tokyo
- Year and Date
  2007-08-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] T型Caチャネル(TCC)抑制による腎、血管保護作用におけるRho-kinaseの関与2006
- Author(s)
  菅野直希, 林晃一, 脇野修, 他
- Organizer
  第10回日本心血管内分泌学会
- Place of Presentation
  福井
- Year and Date
  2006-11-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] The Involvement of Rho-kinase in the Renovascular Protective Effects of T-type Calcium Channel Blockade2006
- Author(s)
  Sugano, N, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 10th Scientific Session of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Fukui
- Year and Date
  2006-11-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] The Expression of T-type Calcium Channel was increased in Chronic Kidney Disease Independently of Blood Pressure2006
- Author(s)
  Sugano, N, Hayashi, K, Wakino, S, et. al.
- Organizer
  The 10th Scientific Session of the Society of Cardiovascular Endocrinology and Metabolism
- Place of Presentation
  Fukui
- Year and Date
  2006-11-18
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590904
[Presentation] T型Caチャネル(TCC)は腎不全で血圧非依存的に発現が亢進する2006
- Author(s)
  菅野直希、林晃一、脇野修, 他
- Organizer
  第10回日本心血管内分泌学会
- Place of Presentation
  福井
- Year and Date
  2006-11-18
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590904

1. WAKINO Shu (50265823)

# of Collaborated Projects: 6 results

# of Collaborated Products: 106 results
2. TOKUYAMA Hirobumi (50276250)

# of Collaborated Projects: 5 results

# of Collaborated Products: 39 results
3. SARUTA Takao (70051571)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
4. HONDA Masanori (20270514)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. KUBOTA Eiji (40255451)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. MATSUDA Hiroto (80245498)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. SASAKI Takayuki (40235255)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. HAYASHIDA Tomoko (20228604)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. OHNO Yoichi (10203895)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. HAYASHI Matsuhiko (60129608)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. KAJIYA Fumihiko (70029114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. TSUJIOKA Katsuhiko (30163801)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. YADA Toyotaka (00210279)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. OGASAWARA Yasuo (10152365)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. GOTO Masami (50148699)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. OKUBO Ken (30286455)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. KANDA Takeshi (80317114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. SUZUKI Hiromichi (80129494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 岡潔 (90233296)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 藤原啓二 (80255463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 仲本博 (10299183)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. 南嶋洋司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 長谷川一宏

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 伊藤裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

HAYASHI Koichi 林 晃一

HAYASHI Kohichi

Research Projects

Research Products

Co-Researchers

Pathophysiology of non-diabetic/obesity induced renal injuries

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Pathophysiological relevance of visceral fat and kidneys in obesity-induced renal injury

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Therapeutic strategy for chronic kidney disease and hypertension based on time/metabolism regulation.Principal Investigator

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Anti-aging therapy against chronic kidney diseasePrincipal Investigator

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The role of Rho/Rho kinase pathway in the metabolic syndrome-associated renal insufficiency

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The investigation of inducing factors of cardiovascular events in early stage of chronic kidney diseasePrincipal Investigator

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Investigation on the role of Rho A in the progression of renal injuryPrincipal Investigator

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Clinial Relevance of Novel Angiotensin II Generation Pathway within the KidneyPrincipal Investigator

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Clinical Relevance of Novel Angiotensin II Generation Pathway within the Kidney

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Evaluation of time sequential changes in subendocardial arteioles in the hypertensive hypertrophic canine heart by using needle-lens CCD intravital microscope

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インシュリン非依存性糖尿病におけ腎障害進展阻止機構の検討Principal Investigator

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Genetic Background and Underlying Mechanism in the Development of Postmenopausal Hypertension

Principal Investigator

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Research Institution

STUDIES ON THE INCIDENCE AND MECHANISM OF HYPERTENSION IN HEMI-NEPHRECTOMIZED SUBJECTS.

Principal Investigator

Project Period (FY)

HAYASHI Koichi 林晃一

[Book] CKDステージとCa拮抗薬の使い分け。降圧薬-俺流処方。伊藤裕編集2011

[Book] 輸入・輸出細動脈。高血圧ナビゲーター(第3版)、熊谷裕生、小室一成、堀内正嗣、森下竜一編2011