SAKAMOTO Hisato 坂本尚登

Researcher Number	80187046
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2009 – 2010: 北里大学, 医学部, 准教授 2008: 北里大学, 医学部, 講師 2000 – 2005: 北里大学, 医学部, 講師 1995 – 1998: 東京医科歯科大学, 医学部, 助手 1992: same as above, Instructor, 医学部, 助手
Review Section/Research Field	Principal Investigator Kidney internal medicine / Kidney internal medicine Except Principal Investigator 内科学一般 / Kidney internal medicine
Keywords	Principal Investigator H^+-ATPase / クロライドチャネル / siRNA / sorting / ClC-5クロライドチャネル / ソーティング / ClC-5チャネル / Dent's disease / monoclonal antibody / endocytosis … More / モノクロナール抗体 / エンドサイトーシス / 細胞内小胞 / Dent's病 / 腎臓 / tubuloglomerular feedback / macula densa cells / expression cloning / juxtaglomerular apparatus / chloride channel / 尿細管-糸球体フィードバック / 緻密斑細胞 / 発現クローニング / 傍糸球体装置 / lectin family protein / proteome / mutation / ClC-5 channel / C1C-5チャネル / レクチンファミリー蛋白 / プロテオーム解析 / Dent(デント)病 / 遺伝子変異 / intercalated cells / gastric cells / Osteoclast / CIC-3 channel / CIC-5 channel / H^--ポンプ / ClC-3クロライドチャネル / 遺伝子形質導入 / デント病 / ClCー5クロライドチャネル / 間在細胞 / 胃酸分泌細胞 / 破骨細胞 / ClC-3チャネル / low molecular V proteinuria weight / cytoplasmic vesicle / CIC-5 chloride channel / Dent病 / ゲノムDNA / CLCN5 / ClC-5 / 低分子タンパク尿 / H^+-ポンプ / CIC-5クロライドチャネル / molecular biology / kidney / patch-clamp / cloning / channel / chloride / マイクロインジェクション / CIC-5 / パッチクランプ / PCR / クローニング / チャネル / クロライド … More Except Principal Investigator HGF / ET / Acute Renal Failure / Nephritis / Mesangial cells / 急性腎不全 / 腎炎 / メサンギウム細胞 / 肝細胞増殖因子 / エンドセリン / calmodulin binding site / reductase domain / MALDI-TOF MS / nitric oxide / furosemide / dexamethasone / aldosterone / microarray analysis / nNOS / macula densa / MALDI-TOF-MS / プロスタグランジンE_2 / マクラデンサ細胞 / TGF機構 Less

腎マクラデンサ細胞のゲノミクスとプロテオミクス
- Principal Investigator
  
  河原克雅
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kitasato University
Molecular Regulatory Mechanism and Physiological Significance of the Chloride Channel(s) localized in Juxtaglomerular ApparatusPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Hisato
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kitasato University
Proteomic Analysis of the Loss of Function induced by Changes in Molecular Structure of ClC-5 Chloride ChannelPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Hisato
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kitasato University
Molecular mechanism of endocytosis disorder induced by mutation of CIC-5 Chloride Channel genePrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Hisato
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Kitasato University
Cellular and Subcellular Immunolocalization of CIC-5 Chloride Channel in the mouse Kidney : Colocalization with H^+-ATPasePrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Hisato
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Medical and Dental University
Molecular biological examination of Calcium-sensitive Chloride Channel expressed in the kidneyPrincipal Investigator
- Principal Investigator
  
  SAKAMOTO Hisato
- Project Period (FY)
  1995 – 1996
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Tokyo Medical and Dental University
Roles of new bioactine substances on renal disease. Basic and clinical studies.
- Principal Investigator
  
  SASAKI Sei
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  内科学一般
- Research Institution
  Tokyo Medical and Dental University

All 2005 2004

All Journal Article

[Journal Article] Identification of a novel protein specifically localized in juxtaglomerular apparatus (JGA) by a specific monoclonal antibody against the conserved N-terminal region2005
- Author(s)
  Sakamoto H., et al.
- Journal Title
  
  J Am Soc Nephrol 16
- Data Source
  KAKENHI-PROJECT-16590799
[Journal Article] Identification of a Novel Protein Specifically Localized in Juxtaglomerular Apparatus (JGA) by a Specific Monoclonal Antibody (MAb) against the Conserved N-terminal Region of ClC Chloride Channels2005
- Author(s)
  Hisato Sakamoto, Takatoshi Matsuo, Takashi Shimizu, Satoko Inoue, Fumihiro Shigei
- Journal Title
  
  J Am Soc Nephrol 16
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590799
[Journal Article] レクチンファミリー蛋白によるCIC-5クロライドチャネルのソーティング制御2004
- Author(s)
  松尾孝敏, 坂本尚登他
- Journal Title
  
  日腎会誌 46
  
  Pages: 215-215
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590799
[Journal Article] Proteomic Analysis Reveals Alteration in Galectin-1 in a Novel Mutant in C-Terminus of CIC-5 Channel-Induced Sorting Disorder from Endoplasmic Reticulum.2004
- Author(s)
  Sakamoto H, et al.
- Journal Title
  
  J Am Soc Nephrol 15
- Data Source
  KAKENHI-PROJECT-16590799
[Journal Article] Proteomic Analysis Reveals Alteration in Galectin-1 in a Novel Mutant in C-Terminus of ClC-5 Channel-Induced Sorting Disorder from Endoplasmic Reticulum.2004
- Author(s)
  Hisato Sakamoto, Takatoshi Matsuo, Takashi Shimizu Masaaki Higashihara.
- Journal Title
  
  J Am Soc Nephrol 15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590799
[Journal Article] Sorting Regulation of ClC-5 Chloride Channel and a Novel Molecule belong to lectin family2004
- Author(s)
  Takatoshi Matsuo, Hisato Sakamoto, Takeshi Shimizu, Satoko Inoue, Ichiro Naito, Masaaki Higashihara
- Journal Title
  
  Jpn J Nephrol 46
  
  Pages: 215-215
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590799
[Journal Article] レクチンファミリー蛋白によるCIC-5クロライドチャネルのソーティング制御2004
- Author(s)
  松尾孝俊, 坂本尚登他
- Journal Title
  
  日腎会誌 46
  
  Pages: 215-215
- Data Source
  KAKENHI-PROJECT-16590799

1. UCHIDA Shinichi (50262184)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. NAGABA Yasushi (40255279)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. NAITO Ichiro

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. SASAKI Sei (60170677)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. ISHIBASHI Kenichi (80223022)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SANO Takashi (50265683)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. SHIMIZU Takeshi (30306568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
8. 河原克雅 (70134525)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 中村和生 (40189030)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 福田英一 (20433716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 安岡有紀子 (50348504)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 河崎雅暢

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

SAKAMOTO Hisato 坂本 尚登

Research Projects

Research Products

Co-Researchers

腎マクラデンサ細胞のゲノミクスとプロテオミクス

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular Regulatory Mechanism and Physiological Significance of the Chloride Channel(s) localized in Juxtaglomerular ApparatusPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Proteomic Analysis of the Loss of Function induced by Changes in Molecular Structure of ClC-5 Chloride ChannelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular mechanism of endocytosis disorder induced by mutation of CIC-5 Chloride Channel genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Cellular and Subcellular Immunolocalization of CIC-5 Chloride Channel in the mouse Kidney : Colocalization with H^+-ATPasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biological examination of Calcium-sensitive Chloride Channel expressed in the kidneyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Roles of new bioactine substances on renal disease. Basic and clinical studies.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Identification of a novel protein specifically localized in juxtaglomerular apparatus (JGA) by a specific monoclonal antibody against the conserved N-terminal region2005

Author(s)

Journal Title

Data Source

[Journal Article] Identification of a Novel Protein Specifically Localized in Juxtaglomerular Apparatus (JGA) by a Specific Monoclonal Antibody (MAb) against the Conserved N-terminal Region of ClC Chloride Channels2005

Author(s)

Journal Title

Description

Data Source

[Journal Article] レクチンファミリー蛋白によるCIC-5クロライドチャネルのソーティング制御2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Proteomic Analysis Reveals Alteration in Galectin-1 in a Novel Mutant in C-Terminus of CIC-5 Channel-Induced Sorting Disorder from Endoplasmic Reticulum.2004

Author(s)

Journal Title

Data Source

[Journal Article] Proteomic Analysis Reveals Alteration in Galectin-1 in a Novel Mutant in C-Terminus of ClC-5 Channel-Induced Sorting Disorder from Endoplasmic Reticulum.2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] Sorting Regulation of ClC-5 Chloride Channel and a Novel Molecule belong to lectin family2004

Author(s)

Journal Title

Description

Data Source

[Journal Article] レクチンファミリー蛋白によるCIC-5クロライドチャネルのソーティング制御2004

Author(s)

Journal Title

Data Source

SAKAMOTO Hisato 坂本尚登