Harabuchi Yasuaki 原渕保明

… Alternative Names

HARABUCHI Yasuaki 原渕保明

原淵保明ハラブチヤスアキ

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Researcher Number	80208686
Other IDs
External Links
Affiliation (Current)	2025: 旭川医科大学, 医学部, 名誉教授
Affiliation (based on the past Project Information) *help	2022 – 2023: 旭川医科大学, 医学部, 名誉教授 2012 – 2021: 旭川医科大学, 医学部, 教授 2005 – 2010: 旭川医科大学, 医学部, 教授 2002: 旭川医科大学, 教授 1998 – 2002: ASAHIKAWA MEDICAL COLLEDE,PROFESSOR, 医学部, 教授 1994 – 1997: 札幌医科大学, 医学部, 講師
Review Section/Research Field	Principal Investigator Otorhinolaryngology / Otorhinolaryngology / Basic Section 56050:Otorhinolaryngology-related Except Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology / Biological Sciences
Keywords	Principal Investigator EBウイルス / 鼻性NK/T細胞リンパ腫 / T細胞リンパ腫 / IMMUNOLOGY / EPSTEIN-BARR VIRUS / 悪性腫瘍 / 悪性リンパ腫 / LMP1 / 鼻性NK / NK/T細胞リンパ腫 … More / promiscuous epitope / EBV DNA / IP-10 / LMP2 / IL-9 / NK-CELL LYMPHOMA / NASAL T / 鼻腔 / VIROLOGY / 頭頸部外科学 / Epstein-Barr virus / ペプチドワクチン / ワクチン / ペプチド / 免疫療法 / 免疫抑制 / 腫瘍抗原 / 免疫チェックポイント / 頭頸部外科 / intra-arterial chemotherapy / T cell lymphoma / nasal NK / 動注化学療法 / NKレセプター / EBV DNA量 / CXCR3 / ケモカイン / 浅側頭動脈動注化学療法 / HEAD AND HECK MALIGNANCIES / P53癌抑制遺伝子 / LMP-2A / LMP-1 / VIROROGY / HEAD AND NECK MALIGNANCIES / 耳下腺 / 頭頚部 / NK細胞リンパ種 / EBウィルス / 上咽頭癌 / ワルダイエル扁桃輪 / NK細胞リンパ腫 / 鼻性T / 頭頚部悪性腫瘍 / POLYMORPHIC RETICULOSIS / NASAL T-CELL LYMPHOMA / LETHAL MIDLINE GRANULOMA / 免疫学 / 進行性鼻壊疸 / 免疫遺伝子 / 多形細網症 / 鼻性T細胞リンパ腫 / 致死性正中肉芽腫症 / miR-15a / CCR4 / chemokine / CD70 / IFN gamma-inducible protein-10 (IP-10) / メタロエラスターゼ / LFA-1 / 単球 / TARC / IFN gamma-inducible protein-10(IP-10) / EBウイルス膜蛋白 / 浅側頭動脈動注・放射線同時併用療法 / monocytes / IP-10 (Interferon gamma-induced protein-10) / LMP1(latent membrane protein 1) / コレラトキシン / リポタイコ酸 / 化膿性レンサ球菌 / P6蛋白 / T細胞エピトープ / インフルエンザ菌 / 中耳炎 / 扁桃炎 … More Except Principal Investigator ワクチン / ペプチド / 免疫チェックポイント / バイオマーカー / 腫瘍免疫 / 免疫療法 / 頭頸部癌 / Adhesion molecules / Neutrophil / Chemokine / Cytokine / Otitis media / 走化因子 / 接着分子 / 好中球 / ケモカイン / サイトカイン / 中耳炎 / 疫学調査 / 中国 / 韓国 / 日本 / 農薬 / EBウィルス / T細胞 / NK / 鼻腔リンパ腫 Less

Establishment of novel immunotherapy against nasal NK/T cell lymphomaPrincipal Investigator
- Principal Investigator
  
  Harabuchi Yasuaki
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
Biomarkers to select the immune checkpoint inhibitor-responder in head and neck cancer
- Principal Investigator
  
  Kumai Takumi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
Developing novel immunotherapy against nasal NK/T cell lymphomaPrincipal Investigator
- Principal Investigator
  
  Harabuchi Yasuaki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  Asahikawa Medical College
Development of novel diagnosis and therapeutic procedures for nasal NK/T-cell lymphoma consists of targeting EBV-associated moleculesPrincipal Investigator
- Principal Investigator
  
  Harabuchi Yasuaki
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
A foundational study for targeted therapy against EB virus and tumor growth factor in nasal NK/T-cell lymphomaPrincipal Investigator
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
Fundamental investigation aimed at EB virus-targeted therapy for nasal NK/T-cell lymphoma.Principal Investigator
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
Development of New diagnostic methods and treatments against EB virus as a target in nasal NK/T cell lymphomaPrincipal Investigator
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
鼻腔NK/T細胞リンパ腫発生要因の疫学的解析
- Principal Investigator
  
  AOZASA Katsuyuki
- Project Period (FY)
  2002
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Review Section
  
  Biological Sciences
- Research Institution
  Osaka University
反復性扁桃炎・中耳炎に対するペプチドワクチン療法の開発Principal Investigator
- Principal Investigator
  
  原渕保明
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
Molecular biologic, immunogenetic, and Epstein-Barr virus studies on nasal NK/T-cell lymphomaPrincipal Investigator
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Asahikawa Medical College
IMMUNOLOGIC, GENETIC AND EPSTEIN-BARR VIROLOGICAL STUDIES OF MALIGNANCIES IN HEAD AND NECK LESIONPrincipal Investigator
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  1996 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  ASAHIKAWA MEDICAL COLLEDE
  Sapporo Medical University
The study of inflammatory and defensive mechanisms in otitis media with effusion.
- Principal Investigator
  
  HIMI Tetsuo
- Project Period (FY)
  1995 – 1997
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  Sapporo Medical University
IMMUNOLOGICAL AND EPSTEIN-BARR VIROLOGICAL STUDIES OF LETHAL MIDLINE GRANULOMAPrincipal Investigator
- Principal Investigator
  
  HARABUCHI Yasuaki
- Project Period (FY)
  1994 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  SAPPORO MEDICAL UNIVERSITY SCHOOL OF MEDICINE

[Book] EBウイルス2015
- Author(s)
  原渕保明
- Total Pages
  232
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-15H04986
[Book] 専門医通信鼻性NK/T細胞リンパ腫2012
- Author(s)
  原渕保明
- Total Pages
  1
- Publisher
  日本耳鼻咽喉科学会
- Data Source
  KAKENHI-PROJECT-24390385
[Book] EBウイルス『臨床7章 : 鼻性NK/T細胞リンパ腫』2008
- Author(s)
  原渕保明, 高原幹
- Total Pages
  10
- Publisher
  診断と治療社
- Data Source
  KAKENHI-PROJECT-20390438
[Book] 今日の耳鼻咽喉科・頭頸部外科治療指針第3版『頭頸部領域の悪性リンパ腫』2008
- Author(s)
  原渕保明
- Total Pages
  4
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20390438
[Book] 今日の耳鼻咽喉科・頭頸部外科治療指針第3版『鼻の特異性炎症』2008
- Author(s)
  原渕保明
- Total Pages
  2
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20390438
[Book] 新しい診断と治療のABC2007
- Author(s)
  原渕保明
- Total Pages
  10
- Publisher
  最新医学社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] Expression of soluble CD27 in extranodal natural killer/T-cell lymphoma, nasal type: potential as a biomarker for diagnosis and CD27/CD70-targeted therapy2023
- Author(s)
  Nagato T, Komatsuda H, Hayashi R, Takahara M, Kishibe K, Yasuda S, Yajima Y, Kosaka A, Ohkuri T, Oikawa K, Harabuchi S, Kono M, Yamaki H, Wakisaka R, Hirata-Nozaki Y, Ohara K, Kumai T, Katada A, Hayashi T, Harabuchi Y, Kobayashi H
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: 72 Issue: 7 Pages: 2087-2098
- DOI
  10.1007/s00262-023-03394-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09599, KAKENHI-PROJECT-21H03082
[Journal Article] The efficacy of PD-1 inhibitors in patients with salivary gland carcinoma: A retrospective observational study2022
- Author(s)
  Sato Ryosuke、Kumai Takumi、Ishida Yoshiya、Yuasa Ryota、Kubota Akinobu、Wakisaka Risa、Komatsuda Hiroki、Yamaki Hidekiyo、Wada Tetsuji、Harabuchi Yasuaki
- Journal Title
  
  Laryngoscope Investigative Otolaryngology
  
  Volume: 7 Issue: 6 Pages: 1808-1813
- DOI
  10.1002/lio2.863
- Data Source
  KAKENHI-PROJECT-20K09724
[Journal Article] IL-2 complex recovers steroid-induced inhibition in immunochemotherapy for head and neck cancer2022
- Author(s)
  Kono Michihisa、Yamaki Hidekiyo、Komatsuda Hiroki、Kumai Takumi、Hayashi Ryusuke、Wakisaka Risa、Sato Ryosuke、Ohara Kenzo、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Harabuchi Yasuaki
- Journal Title
  
  Translational Oncology
  
  Volume: 18 Pages: 101358-101358
- DOI
  10.1016/j.tranon.2022.101358
- Data Source
  KAKENHI-PROJECT-20K09724
[Journal Article] Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma2022
- Author(s)
  Kono Michihisa、Komatsuda Hiroki、Yamaki Hidekiyo、Kumai Takumi、Hayashi Ryusuke、Wakisaka Risa、Nagato Toshihiro、Ohkuri Takayuki、Kosaka Akemi、Ohara Kenzo、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  OncoImmunology
  
  Volume: 11 Issue: 1
- DOI
  10.1080/2162402x.2021.2021619
- Data Source
  KAKENHI-PROJECT-20K09724
[Journal Article] A critical role of STING-triggered tumor-migrating neutrophils for anti-tumor effect of intratumoral cGAMP treatment2021
- Author(s)
  Nagata Marino、Kosaka Akemi、Yajima Yuki、Yasuda Syunsuke、Ohara Mizuho、Ohara Kenzo、Harabuchi Shohei、Hayashi Ryusuke、Funakoshi Hiroshi、Ueda Jun、Kumai Takumi、Nagato Toshihiro、Oikawa Kensuke、Harabuchi Yasuaki、Esteban Celis、Ohkuri Takayuki、Kobayashi Hiroya
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: epub Issue: 8 Pages: 2301-2312
- DOI
  10.1007/s00262-021-02864-0
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K06452
[Journal Article] Interruption of MDM2 signaling augments MDM2-targeted T cell-based antitumor immunotherapy through antigen-presenting machinery2021
- Author(s)
  Kono Michihisa、Kumai Takumi、Hayashi Ryusuke、Yamaki Hidekiyo、Komatsuda Hiroki、Wakisaka Risa、Nagato Toshihiro、Ohkuri Takayuki、Kosaka Akemi、Ohara Kenzo、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Celis Esteban、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: epub Issue: 12 Pages: 3421-3434
- DOI
  10.1007/s00262-021-02940-5
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Expression of placenta-specific 1 and its potential for eliciting anti-tumor helper T-cell responses in head and neck squamous cell carcinoma2020
- Author(s)
  Hayashi Ryusuke、Nagato Toshihiro、Kumai Takumi、Ohara Kenzo、Ohara Mizuho、Ohkuri Takayuki、Hirata-Nozaki Yui、Kosaka Akemi、Yasuda Syunsuke、Oikawa Kensuke、Kono Michihisa、Kishibe Kan、Takahara Miki、Katada Akihiro、Hayashi Tatsuya、Celis Esteban、Harabuchi Yasuaki、Kobayashi Hiroya et al
- Journal Title
  
  OncoImmunology
  
  Volume: 10 Issue: 1 Pages: 1856545-1856545
- DOI
  10.1080/2162402x.2020.1856545
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Extranodal Natural Killer/T-Cell Lymphoma, Nasal Type: Basic Science and Clinical Progress2019
- Author(s)
  Harabuchi Yasuaki、Takahara Miki、Kishibe Kan、Nagato Toshihiro、Kumai Takumi
- Journal Title
  
  Frontiers in Pediatrics
  
  Volume: 7 Pages: 141-141
- DOI
  10.3389/fped.2019.00141
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-16K20223
[Journal Article] Phosphorylated vimentin as an immunotherapeutic target against metastatic colorectal cancer.2019
- Author(s)
  Ohara M, Ohara K, Kumai T, Ohkuri T, Nagato T, Hirata-Nozaki Y, Kosaka A, Nagata M, Hayashi R, Harabuchi S, Yajima Y, Oikawa K, Harabuchi Y, Sumi Y, Furukawa H, Kobayashi H.
- Journal Title
  
  Cancer Immunol Immunother.
  
  Volume: ePub Issue: 6 Pages: 989-999
- DOI
  10.1007/s00262-020-02524-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K07452
[Journal Article] PD-L1-specific helper T-cells exhibit effective antitumor responses: new strategy of cancer immunotherapy targeting PD-L1 in head and neck squamous cell carcinoma.2019
- Author(s)
  Hirata-Nozaki Y, Ohkuri T, Ohara K, Kumai T, Nagata M, Harabuchi S, Kosaka A, Nagato T, Ishibashi K, Oikawa K, Aoki N, Ohara M, Harabuchi Y, Uno Y, Takei H, Celis E, Kobayashi H.
- Journal Title
  
  J Transl Med.
  
  Volume: 17 Issue: 1
- DOI
  10.1186/s12967-019-1957-5
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Intratumoral STING activations overcome negative impact of cisplatin on antitumor immunity by inflaming tumor microenvironment in squamous cell carcinoma.2019
- Author(s)
  Harabuchi S, Kosaka A, Yajima Y, Nagata M, Hayashi R, Kumai T, Ohara K, Nagato T, Oikawa K, Ohara M, Harabuchi Y, Ohkuri T, Kobayashi H.
- Journal Title
  
  Biochem Biophys Res Commun.
  
  Volume: 522 Issue: 2 Pages: 408-414
- DOI
  10.1016/j.bbrc.2019.11.107
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18H02948, KAKENHI-PROJECT-19K18791
[Journal Article] Cyclin-dependent kinase 1 and survivin as potential therapeutic targets against nasal natural killer/T-cell lymphoma2019
- Author(s)
  Nagato Toshihiro、Ueda Seigo、Takahara Miki、Kishibe Kan、Komabayashi Yuki、Kumai Takumi、Ohara Kenzo、Hirata-Nozaki Yui、Harabuchi Shohei、Hayashi Ryusuke、Ohkuri Takayuki、Bernasconi Michele、Nadal David、Kobayashi Hiroya、Harabuchi Yasuaki
- Journal Title
  
  Laboratory Investigation
  
  Volume: 99 Issue: 5 Pages: 612-624
- DOI
  10.1038/s41374-018-0182-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] 鼻性NK/T細胞リンパ腫に対する革新的免疫療法の開発2018
- Author(s)
  長門利純、熊井琢美,、高原幹、大栗敬幸、小林博也、Celis Esteban、原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー
  
  Volume: 36 Pages: 15-22
- NAID
  130006619256
- Data Source
  KAKENHI-PROJECT-18H02948
[Journal Article] Novel treatment for early-stage nasal natural killer/T-cell lymphoma: intra-maxillary arterial infusion chemotherapy with concomitant radiotherapy2017
- Author(s)
  Takahara Miki、Nagato Toshihiro、Kishibe Kan、Ueda Seigo、Komabayashi Yuki、Yamashina Masaaki、Takahashi Kouji、Harabuchi Yasuaki
- Journal Title
  
  Hematological Oncology
  
  Volume: 35 Issue: 2 Pages: 158-162
- DOI
  10.1002/hon.2273
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H04986
[Journal Article] 鼻性NK/T細胞リンパ腫2017
- Author(s)
  熊井琢美, 原渕保明
- Journal Title
  
  耳鼻咽喉科・頭頸部外科
  
  Volume: 89 Pages: 1018-1028
- NAID
  10030285840
- Data Source
  KAKENHI-PROJECT-15H04986
[Journal Article] Programmed death-ligand 1 and its soluble form are highly expressed in nasal natural killer/T-cell lymphoma: a potential rationale for immunotherapy2017
- Author(s)
  Toshihiro Nagato, Takayuki Ohkuri, Kenzo Ohara, Yui Hirata, Kan Kishibe, Yuki Komabayashi, Seigo Ueda, Miki Takahara, Takumi Kumai, Kei Ishibashi, Akemi Kosaka, Naoko Aoki, Kensuke Oikawa, Yuji Uno, Naoko Akiyama, Masatoshi Sado, Hidehiro Takei, Esteban Celis, Yasuaki Harabuchi, Hiroya Kobayashi
- Journal Title
  
  Cancer Immunol Immunother
  
  Volume: 印刷中 Issue: 7 Pages: 877-890
- DOI
  10.1007/s00262-017-1987-x
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26462576, KAKENHI-PROJECT-15K20172, KAKENHI-PROJECT-15K20174, KAKENHI-PROJECT-15H04986
[Journal Article] CCL17 and CCL22/CCR4 signaling is a strong candidate for novel targeted therapy against nasal natural killer/T-cell lymphoma2015
- Author(s)
  Takumi Kumai, Toshihiro Nagato, Hiroya Kobayashi, Yuki Komabayashi, Seigo Ueda, Kan Kishibe, Takayuki Ohkuri, Miki Takahara, Esteban Celis, Yasuaki Harabuchi
- Journal Title
  
  Cancer Immunology, Immunotherapy
  
  Volume: - Issue: 6 Pages: 697-705
- DOI
  10.1007/s00262-015-1675-7
- NAID
  120005774022
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24390385, KAKENHI-PROJECT-15H04986
[Journal Article] Monocytes enhance cell proliferation and LMP1 expression of nasal natural killer (NK)/T-cell lymphoma cells by cell contact-dependent interaction though membrane-bound IL-15.2011
- Author(s)
  Ishii H, Takahara M, Nagato T, Kishibe K, Kis L, Harabuchi Y, Klein G, Klein E
- Journal Title
  
  Int J Cancer. (in press)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Production of interferon-{gamma}-inducible protein-10 and its role as an autocrine invasion factor in nasal natural killer/T-cell lymphoma cells.2010
- Author(s)
  Moriai S, Takahara M, Ogino T, Nagato T, Kishibe K, Ishii H, Katayama A, Shimizu N, Harabuchi Y.
- Journal Title
  
  Clin Cancer Res. 15.
  
  Pages: 6771-6779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 耳鼻咽喉・頭頸部画像アトラス頭頸部悪性リンパ腫2010
- Author(s)
  原渕保明,長門利純
- Journal Title
  
  JOHNS 26
  
  Pages: 505-509
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 耳鼻咽喉・頭頸部画像アトラス頭頸部悪性リンパ腫2010
- Author(s)
  原渕保明
- Journal Title
  
  JOHNS
  
  Volume: 26 Pages: 505-509
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] HLA class I antigen and transporter associated with antigen processing downregulation in metastatic lesions of head and neck squamous cell carcinoma as a marker of poor prognosis.2010
- Author(s)
  Bandoh N, Ogino T, Katayama A, Takahara M, Katada A, Hayashi T, Harabuchi Y.
- Journal Title
  
  Oncol Rep. 23
  
  Pages: 933-939
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Production of interferon -gamma- inducible protein-10(IP-10)and its role as an autocrine invasion factor in nasal natural killer(NK)/T-cell lymphoma cells2009
- Author(s)
  Moriai S, Takahara M, Ogino T, Nagato T, Kishibe K, Ishii H, Katayama A, Shimizu N, Harabuchi Y.
- Journal Title
  
  Clin Cancer Res 15
  
  Pages: 6771-6779
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Up-regulation of CC chemokine reseptor 6 on tonsillar T cells and its induction by in vitro stimulation with α-streptococci in patients with pustulosis palmaris et plantaris2009
- Author(s)
  Yoshizaki T, Bandoh N, Nozawa H, Goto T, Kishibe K, Takahara M, Harabuchi Y.
- Journal Title
  
  Clinical and Experimental Immunology 157
  
  Pages: 71-82
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 鼻性NK/T細胞リンパ腫におけるmetalloelastaseの発現2009
- Author(s)
  岸部幹, 長門利純, 森合重誉, 高原幹, 荻野武, 原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 27
  
  Pages: 124-125
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 耳鼻咽喉科ウイルス感染症EBウイルス感染と頭頸部腫瘍2009
- Author(s)
  高原幹, 原渕保明
- Journal Title
  
  ENTONI 99
  
  Pages: 49-56
- NAID
  120005311882
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 鼻性NK/T細胞リンパ腫におけるCD70の発現2009
- Author(s)
  吉野和美, 片山昭公, 岸部幹, 長門利純, 石井秀幸, 高原幹, 原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 27
  
  Pages: 122-123
- NAID
  120004184761
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] ウイルス性疾患外来における抗ウイルス薬の使い方2009
- Author(s)
  高原幹,原渕保明
- Journal Title
  
  ENTONI 100
  
  Pages: 155-162
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Nasal natural killer(NK)/T-cell lymphoma : clinical, histological, virological, and genetic features2009
- Author(s)
  Harabuchi Y, Takahara M, Kishibe K, Moriai S, Nagato T, Ishii H.
- Journal Title
  
  Int J Clin Oncol 14
  
  Pages: 181-190
- NAID
  10025148003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 鼻性NK/T細胞リンパ腫細胞株における可溶性ICAM1の解析2009
- Author(s)
  高原幹, 岸部幹, 石井秀幸, 片山昭公, 林達哉, 原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 27
  
  Pages: 222-223
- NAID
  10030883523
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Nasal natural killer (NK)/T-cell lymphoma : clinical, histological, virological, and genetic features.2009
- Author(s)
  Harabuchi Y, Takahara M, Kishibe K, Moriai S, Nagato T, Ishii H.
- Journal Title
  
  Int J Clin Oncol. 14
  
  Pages: 181-190
- NAID
  10025148003
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] EBウイルス感染と頭頸部腫瘍2009
- Author(s)
  高原幹,原渕保明
- Journal Title
  
  ENTONI 99
  
  Pages: 49-56
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] romiscuous peptides on the nontypeable Haemophilus influenzae P6 outer membrane protein2008
- Author(s)
  Nomura Y, Abe Y, Ishida Y, Kobayashi H, Harabuchi Y.
- Journal Title
  
  J Clin Immunol 28
  
  Pages: 361-369
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Selective expansion of TCR V beta 6 in tonsillar T-cells induced by H. parainfluenzae in patients with IgA nephropathy2008
- Author(s)
  Nozawa H, Takahara M, Yoshizaki T, Goto T, Bandoh N, Harabuchi Y
- Journal Title
  
  Clinical and Experimental Immunology 151
  
  Pages: 25-33
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Induction of EBV-latent membrane protein 1-specific MHC class II-restricted T-cell responses against natural killer lymphoma cells.2008
- Author(s)
  Kobayashi H, Nagato T, Takahara M, Sato K, Kimura S, Aoki N, Azumi M, Tateno M, Harabuchi Y, Celis E
- Journal Title
  
  Cancer Res 68
  
  Pages: 901-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] 臨床7章:鼻性NK/T細胞リンパ腫2008
- Author(s)
  原渕保明,高原幹
- Journal Title
  
  EBウイルス(高田賢蔵編)(診断と治療社)
  
  Pages: 130-140
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 頭頸部領域の悪性リンパ腫2008
- Author(s)
  原渕保明
- Journal Title
  
  今日の耳鼻咽喉科・頭頸部外科治療指針第3版(森山寛, 他編)(医学書院)
  
  Pages: 246-484
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Induction of EBV-latent membrane protein 1-specific MHC class II-restricted T-cell responses against natural killer lymphoma cells.2008
- Author(s)
  Kobayashi H, Nagato T, Takahara M, Sato K, Kimura S, Aoki N, Azumi M, Tateno M, Harabuchi Y, Celis E.
- Journal Title
  
  Cancer Res. 68
  
  Pages: 901-908
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 鼻性NK/T細胞リンパ腫におけるmetalloelastaseの発現2008
- Author(s)
  岸部幹, 長門利純, 森合重誉, 高原幹, 荻野武, 原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 26
  
  Pages: 101-102
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 鼻性NK/T細胞リンパ腫細胞株SNK6におけるLFA-1とICAM1の機能解析2008
- Author(s)
  高原幹, 岸部幹, 森合重誉, 坂東伸幸, 荻野武, 原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 26
  
  Pages: 104-105
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] 鼻性NK/T細胞リンパ腫におけるIP-10の発現と機能2008
- Author(s)
  森合重誉, 高原幹, 長門利純, 岸部.幹, 荻野武, 原渕保明
- Journal Title
  
  耳鼻咽喉科免疫アレルギー 26
  
  Pages: 102-103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Increase in B-cell-activation factor (BAFF) and IFN-gamma productions by tonsillar mononuclear cells stimulated with deoxycytidyl-deoxyguanosine oligodeoxynucleotides (CpG-ODN) in patients with IgA nephropathy2008
- Author(s)
  Goto T, Bandoh N, Yoshizaki T, Nozawa H, Takahara M, Ueda S, Hayashi T, Harabuchi Y.
- Journal Title
  
  Clin Immunol 126
  
  Pages: 260-269
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20390438
[Journal Article] Selected amino acid change encoding Epstein-Barr virus-specific T cell epitope of the LMP2A gene in Japanese nasal NK/T cell lymphoma patients.2007
- Author(s)
  Nagamine M, Kishibe K, Takahara M, Nagato T, Ishii H, Bandoh N, Ogino T, Harabuchi Y
- Journal Title
  
  Intervirology 50
  
  Pages: 319-322
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] Sequence variations of Epstein-Barr virus LMP 1 gene in nasal NK/T-cell lymphoma.2007
- Author(s)
  Nagamine M, Takahara M, Kishibe K, Nagato T, Ishii H, Bandoh N, Ogino T, Harabuchi Y
- Journal Title
  
  Virus Genes 34
  
  Pages: 47-54
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] Clinical usefulness of serum EBV DNA levels of BamHI W and LMPl for Nasal NK/T-cell lymphoma.2007
- Author(s)
  Ishii H, Ogino T, Berger C, Kochli-Schmitz N, Nagato T, Takahara M, Nadal D, Harabuchi Y
- Journal Title
  
  J Med Virol 79
  
  Pages: 562-572
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] 鼻性NK/T細胞リンパ腫症例で学ぶ鼻科診療の実際2006
- Author(s)
  原渕保明
- Journal Title
  
  鼻アレルギーフロンティア 6
  
  Pages: 41-46
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] Concomitant increase of LMP1 and CD25 (IL-2-receptor alpha) expression induced by IL-10 in the EBV-positive NK lines SNK6 and KAI3.2006
- Author(s)
  Takahara M, Kis LL, Nagy N, Liu A, Harabuchi Y, Klein G, Klein E
- Journal Title
  
  Int J Cnacer 119
  
  Pages: 2775-2783
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] Life-style and environmental factors in the development of nasal NK/T-cell lymphoma: a case-control study in East Asia.2006
- Author(s)
  Xu JX, Hoshida Y, Yang WI, Inohara H, Kubo T, Kim GE, Yoon JH, Kojya S, Bandoh N, Harabuchi Y, Tsutsumi K, Koizuka I, Jia XS, Kirihata M, Tsukuma H, Aozasa K
- Journal Title
  
  Int J Cancer 15
  
  Pages: 406-10
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] 鼻性NK/T細胞リンパ腫のEBウイルス学的、分子腫瘍学的解析2006
- Author(s)
  原渕保明
- Journal Title
  
  耳鼻免疫アレルギー 24
  
  Pages: 1-9
- NAID
  10018168471
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] Expression of Interleukin-9 in Nasal Natural Killer/T-cell Lymphoma Cell Lines and Patients.2005
- Author(s)
  Nagato T, Kobayashi H, Kishibe K, Takahara M, Ogino T, Ishii H, Oikawa K, Aoki N, Sato K, Kimura S, Simizu N, Tateno M, Harabuchi Y.
- Journal Title
  
  Clin Cancer Res 11
  
  Pages: 8250-8257
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] 特集・ステロイド薬の正しい使い方悪性リンパ腫-耳鼻科医の立場から-2005
- Author(s)
  原渕保明
- Journal Title
  
  ENTONI 48
  
  Pages: 90-95
- Data Source
  KAKENHI-PROJECT-17390455
[Journal Article] p53, K-ras, c-kit and beta-catenin gene mutations in sinonasal NK/T-cell lymphoma in Korea and Japan.2005
- Author(s)
  Hongyo T, Hoshida Y, Nakatsuka S, Syaifudin M, Kojya S, Yang WI, Min YH, Chan H, Kim CH, Harabuchi Y, Himi T, Inuyama M, Aozasa K, Nomura T
- Journal Title
  
  Oncol Rep 13
  
  Pages: 265-71
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Presentation] C-met as an novel antigen in extranodal NK/T cell lymphoma, nasal type for helper T cell-based immunotherapy2021
- Author(s)
  Nozaki Y, Kumai T, Komatsuda H, Kono M, Yamaki H, Kishibe K, Takahara M, Hayashi T, Harabuchi Y
- Organizer
  The 19th International Symposium on Epstein-Barr Virus and associated diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03082
[Presentation] Expression of cyclin-dependent kinase 1 and survivin in nasal natural killer/T-cell lymphoma2019
- Author(s)
  Hayashi R, Nagato T, Harabuchi S, Kumai T, Kishibe K, Takahara M, Kobayashi H, Harabuchi Y
- Organizer
  ISIAN・IRS・ARS (RhinoWorld Chicago 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression and function of Epstein-Barr virus-encoded microRNAs in nasal natural killer/ T-cell lymphoma2019
- Author(s)
  Kishibe K, Komabayashi Y, Hayashi R, Kumai T, Takahara M, Harabuchi Y
- Organizer
  ISIAN・IRS・ARS (RhinoWorld Chicago 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫および上咽頭癌におけるCD74とMIFの発現2019
- Author(s)
  熊井琢美, 林　隆介, 長門利純, 原渕翔平, 岸部　幹, 高原　幹, 永田真莉乃, 矢島優己, 小坂　朱, 大栗敬幸, 及川賢輔, 小林博也, 原渕保明
- Organizer
  第16回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫６７症例の臨床学的検討2019
- Author(s)
  高原　幹, 熊井琢美, 岸部　幹, 片田彰博, 林　達哉, 原渕保明
- Organizer
  第33回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCD27の発現2019
- Author(s)
  長門利純, 林　隆介, 原渕翔平, 野﨑　結, 大原賢三, 熊井琢美, 岸部　幹, 高原　幹, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Cancer Immunity Cycleと化学療法2019
- Author(s)
  原渕翔平, 大原賢三, 野﨑　結, 熊井琢美, 長門利純, 林　達哉, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫67症例の臨床学的検討2019
- Author(s)
  高原　幹, 熊井琢美, 岸部　幹, 片田彰博, 林　達哉, 原渕保明
- Organizer
  第16回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] マウス扁平上皮癌モデルを用いた、化学療法とSTING活性化療法の併用に関する基礎研究2019
- Author(s)
  原渕翔平, 大栗敬幸, 小坂　朱, 永田真莉乃, 林　隆介, 大原賢三, 大原みずほ, 長門利純, 及川賢輔, 小林博也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCDK1とサバイビンの発現2019
- Author(s)
  熊井琢美, 長門利純, 高原　幹, 原渕保明
- Organizer
  第33回ヘルペスウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 頭頸部悪性腫瘍におけるCD74の発現2019
- Author(s)
  林　隆介, 長門利純, 永田真莉乃, 原渕翔平, 大原賢三, 大原みずほ, 小坂朱, 大栗敬幸, 及川賢輔, 小林博也
- Organizer
  第108回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression of cell surface CD74 and macrophage migration inhibitory factor in malignant tumors of head and neck region2019
- Author(s)
  Hayashi R, Nagato T, Kumai T, Nagata M, Harabuchi S, Yajima Y, Kosaka A, Ohkuri T, Oikawa K, Kishibe K, Takahara M, Harabuchi Y, Kobayashi H
- Organizer
  第78回日本癌学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫における免疫抑制サイトカインの検討2019
- Author(s)
  熊井琢美, 長門利純, 岸部　幹, 高原　幹, 青木直子, 及川賢輔, 林　達哉, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫における免疫抑制サイトカインの検討2019
- Author(s)
  熊井琢美、長門利純、林隆介、原渕翔平、岸部幹、高原幹、林達哉、小林博也、原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] リン酸化抗原特異的T細胞を利用した悪性腫瘍に対するペプチドワクチン療法の基礎的解析2019
- Author(s)
  大原賢三, 熊井琢美, 長門利純, 林　隆介, 原渕翔平, 小林博也, 原渕保明
- Organizer
  第37回日本耳鼻咽喉科免疫アレルギー学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCD74とMIFの発現2019
- Author(s)
  林　隆介, 長門利純, 原渕翔平, 熊井琢美, 岸部　幹, 高原　幹, 小林博也, 原渕保明
- Organizer
  第58回日本鼻科学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Arterial infusion chemotherapy from superficial temporal artery in combination with radiotherapy for early stage nasal NK/T cell lymphoma2019
- Author(s)
  Wakisaka R, Takahara M, Kishibe K, Katada A, Hayashi T, Harabuchi Y
- Organizer
  ISIAN・IRS・ARS (RhinoWorld Chicago 2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Sustained persistence of IL-2 signaling enhances the antitumor effect of peptide vaccines2019
- Author(s)
  Kumai T, Sultan H, Harabuchi Y, Celis E
- Organizer
  American Assiciation for Cancer Research Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression and function of Epstein-Barr virus-encoded microRNAs in nasal natural killer/T-cell lymphoma2018
- Author(s)
  Kishibe K, Komabayashi Y, Kumai T, Nagato T, Takahara M, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] A clinical and pathological characterization of Epstein-Barr virus positive methotrexate-associated lymphoproliferative disorders for seven cases2018
- Author(s)
  Araki D, Kumai T, Nagato T, Kishibe K, Takahara M, Katada A, Hayashi T, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Diagnostic values of circulating Epstein-Barr virus-encoded microRNAs as potential biomarkers for nasal natural killer/T-cell lymphoma2018
- Author(s)
  Komatsuda H, Kishibe K, Komabayashi Y, Nagato T, Takahara M, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Expression of programmed death-ligand 1 in nasal natural killer/T-cell lymphoma2018
- Author(s)
  Nagato t, Ohkuri T, Ohara K, Nozaki Y, Kishibe K, Takahara M, Kumai T, Araki D, Komabayashi H, Kobayashi H, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫におけるCDK1とサバイビンの発現2018
- Author(s)
  長門利純、大原賢三、原渕翔平、林隆介、大栗敬幸、永田真莉乃、大原みずほ、小坂朱、青木直子、及川賢輔、原渕保明、小林博也
- Organizer
  第51回北海道病理談話会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫に対する放射線同時併用動注化学療法2018
- Author(s)
  脇坂理紗、高原幹、長門利純、岸部幹、片田彰博、林達哉、原渕保明
- Organizer
  第57回日本鼻科学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] The identification of extranodal NK/T cell lymphoma, nasal type-associated antigen for helper T cell-based immunotherapy2018
- Author(s)
  Kumai T, Komatsuda H, Araki D, Nagato T, Kishibe K, Takahara M, Hayashi T, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] ワークショップ１０：「病理学的解析が拓くがん免疫研究の進展と未来」鼻性NK/T細胞リンパ腫における免疫抑制機構の解明と新規免疫療法の開発2018
- Author(s)
  長門利純、原渕保明、小林博也
- Organizer
  第107回日本病理学会総会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Special Lecture1: Clinical, pathologic and Epstein-Barr virus features of nasal NK/T cell lymphoma2018
- Author(s)
  Harabuchi Y
- Organizer
  The 55th Korean Rhinologic Society Annual Congress (KRS)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 鼻性NK/T細胞リンパ腫における免疫抑制サイトカインの検討2018
- Author(s)
  熊井琢美、長門利純、岸部幹、高原幹、青木直子、及川賢輔、林達哉、小林博也、原渕保明
- Organizer
  第15回EBウイルス研究会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] Clinical inverstigation of 64 pationts with nasal NK/T-cel lymphoma2018
- Author(s)
  Takahara M, Nagato T, Kishibe K, Katada A, Hayashi T, Harabuchi Y
- Organizer
  International Conference on EBV & KSHV 2018
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] EBウイルス陽性鼻性NK/T細胞リンパ腫に対するペプチドワクチン療法の開発2018
- Author(s)
  原渕翔平、熊井琢美、長門利純、林達哉、原渕保明
- Organizer
  第57回日本鼻科学会
- Data Source
  KAKENHI-PROJECT-18H02948
[Presentation] 進行性鼻壊疽から鼻性NK/T細胞リンパ腫へ2017
- Author(s)
  原渕保明
- Organizer
  第90回日耳鼻千葉県地方部会学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04986
[Presentation] The identification of nasal NK/T-cell lymphoma-associated antigens for helper T cell-based immunotherapy2017
- Author(s)
  Kumai T, Nagato T, Takahara M, Katada A, Hayashi T, Harabuchi Y
- Organizer
  The 53rd Korean Rhinologic Society Annual Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H04986
[Presentation] 鼻腔に発生する致死性肉芽腫の謎を解く2017
- Author(s)
  原渕保明
- Organizer
  第111回鹿児島県耳鼻咽喉科学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-15H04986
[Presentation] 宿題報告　進行性鼻壊疽から鼻性NK/T細胞リンパ腫へ2016
- Author(s)
  原渕保明
- Organizer
  日本耳鼻咽喉科学会
- Place of Presentation
  名古屋
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-15H04986
[Presentation] Expression and function of LFA-1 and ICAM-1 in nasal NK/T cell lymphoma cells.2013
- Author(s)
  Yasuaki Harabuchi
- Organizer
  15th Asian Research Symposium in Rhinology
- Place of Presentation
  Tokyo
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] Nasal NK/T-cell lymphoma; its genetic features associated with Epstein-Barr virus2013
- Author(s)
  Yasuaki Harabuchi
- Organizer
  The 18th International Symposiumon Tonsils and Mucosal Barriers of the Upper Airways
- Place of Presentation
  Zurich, Switzerland
- Invited
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] Expression of chemokines in nasal natural killer/T-cell lymphoma.2010
- Author(s)
  長門利純, Kishibe K, 吉野和美, 高原幹, 原渕保明
- Organizer
  EBV meeting 2010
- Place of Presentation
  Birmingham UK
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Nasal NK/T-cell lymphoma -Association with Epstein-Barr virus, contributing to lymphomagenesis.2010
- Author(s)
  原渕保明
- Organizer
  Experimental Infectious Diseases and Cancer Research, University Children's Hospital
- Place of Presentation
  Zurich, Switzerland.(Invited Lecture)
- Year and Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 鼻性NK/T細胞リンパ腫におけるケモカインの発現2010
- Author(s)
  長門利純,岸部幹,吉野和美,高原幹,原渕保明
- Organizer
  第34回日本頭頸部癌学会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of MicroRNAs in Nasal Natural Killer/T-Cell Lymphoma Cell Lines.2010
- Author(s)
  Kishibe K, Yoshino K, Katayama A, Nagato T, Takahara M, Harabuchi Y.
- Organizer
  EBV meeting 2010
- Place of Presentation
  Birmingham UK
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Nasal NK/T-cell lymphoma -Association with Epstein-Barr virus, contributing to lymphomagenesis2010
- Author(s)
  Harabuchi Y.
- Organizer
  Invited Lecture
- Place of Presentation
  Experimental Infectious Diseases and Cancer Research, University Children's Hospital
- Year and Date
  2010-09-08
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 頭頸部悪性リンパ腫の病態と臨床-鼻性NK/T細胞リンパ腫を中心に-2010
- Author(s)
  原渕保明
- Organizer
  第17回千葉頭頸部腫瘍研究会
- Place of Presentation
  千葉(特別講演)
- Year and Date
  2010-02-27
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression and function of LFA-1 and ICAM-1 in nasal NK/T cell lymphoma cells.2010
- Author(s)
  Takahara M, Yoshino K, Nagato T, Kishibe K, Katayama A, Harabuchi Y.
- Organizer
  The 14th Biennial Conference of the International Association for Research on Epstein-Barr Virus and Associated Disease (EBV meeting 2010)
- Place of Presentation
  Birmingham,UK
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of CD70 in Nasal Natural Killer/T-cell Lymphoma. 吉野和美2010
- Author(s)
  Kishibe K, Katayama A, Nagato T, Takahara M, Harabuchi Y.
- Organizer
  EBV meeting 2010
- Place of Presentation
  Birmingham UK
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 鼻性NK/T細胞リンパ腫細胞株におけるLFA-1とICAM1の解析2010
- Author(s)
  高原幹,岸部幹,片山昭広,林達也,原渕保明
- Organizer
  第28回日耳鼻免疫アレルギー学会
- Place of Presentation
  福井
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression and function of LFA-1 and ICAM-1 in nasal NK/T cell lymphoma2009
- Author(s)
  Takahara M, Kishibe K, Nagato T, Moriai S, Ishii H, Katayama A, Harabuchi Y
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] New Treatment and Monitoring Procedures for Nasal NK/T-cell Lymphoma, Intra-Maxillary Arterial Chemotherapy and Analysis of Serum EBV DNA2009
- Author(s)
  Takahara M, Kishibe K, Nagato T, Moriai S, Ishii H, Katayama A, Harabuchi Y.
- Organizer
  The 10th Japan-Taiwan Conference in Oto-Rhino-Laryngology, Head and Neck Surgery
- Place of Presentation
  Yilan, Taiwan
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 鼻性NK/T細胞リンパ腫に対する放射線同時併用動注化学療法2009
- Author(s)
  高原幹, 岸部幹, 石井秀幸, 森合重誉, 原渕保明
- Organizer
  第110回日本耳鼻咽喉科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 鼻性NK/T細胞リンパ腫におけるmicroRNAの発現2009
- Author(s)
  岸部幹,吉野和美,長門利純,高原幹,片山昭公,林達哉,原渕保明
- Organizer
  第48回日本鼻科学会
- Place of Presentation
  島根
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of CD70 in Nasal Natural Killer/T-cell Lymphoma2009
- Author(s)
  Yoshino K, Kishibe K, Katayama A, Nagato T, Takahara M, Harabuchi Y
- Organizer
  The 113th American Academy of Otolaryngology Head and Neck Surgery Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression and function of LFA-1 and ICAM-1 in nasal NK/T cell lymphoma.2009
- Author(s)
  Takahara M, Kishibe K, Nagato T, Moriai S, Ishii H, Katayama A, Harabuchi Y.
- Organizer
  第68回日本癌学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of MMP-12 in Nasal NK/T Cell Lymphoma2009
- Author(s)
  Kishibe K, Yoshino K, Nagato T, Takahara M, Katayama A, Harabuchi Y
- Organizer
  The 113th American Academy of Otolaryngology Head and Neck Surgery Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 鼻性NK/T細胞リンパ腫に対する放射線同時併用動注化学療法2009
- Author(s)
  高原幹, 長門利純, 岸部幹, 森合重誉, 片山昭広, 林達哉, 原渕保明
- Organizer
  第47回日本癌治療学会
- Place of Presentation
  横浜
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] New Treatment and Monitoring Procedures for Nasal NK/T-cell Lymphoma, Intra-Maxillary Arterial Chemotherapy and Analysis of Serum EBV DNA.2009
- Author(s)
  Takahara M, Kishibe K, Nagato T, Moriai S, Ishii H, Katayama A, Harabuchi Y.
- Organizer
  The 10th Japan-Taiwan Conference in Oto-Rhino-Laryngology, Head and Neck Surgery
- Place of Presentation
  Yilan,Taiwan
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of CD70 in Nasal Natural Killer/T-cell Lymphoma.2009
- Author(s)
  Yoshino K, Kishibe K, Katayama A, Nagato T, Takahara M, Harabuchi Y.
- Organizer
  The 113th American Academy of Otolaryngology-Head and Neck Surgery Annual Meeting
- Place of Presentation
  San Diego,USA
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] 単球が誘導したと考えられる鼻性NK/T細胞リンパ腫の増殖とLMP1発現の検討2009
- Author(s)
  石井秀幸, 高原幹, 片山昭公, 坂東伸幸, 片田彰博, 林達哉, 原渕保明
- Organizer
  第110回日本耳鼻咽喉科学会総会
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of MMP-12 in Nasal NK/T Cell Lymphoma.2009
- Author(s)
  Kishibe K, Yoshino K, Nagato T, Takahara M, Katayama A, Harabuchi Y.
- Organizer
  The 113th American Academy of Otolaryngology-Head and Neck Surgery Annual Meeting
- Place of Presentation
  San Diego, USA
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] New treatment and monitoring procedures for nasal NK/T-cell lymphoma : intra-maxillary arterial chemotherapy and analysis of serum EBV DNA2008
- Author(s)
  Takahara M, Ishii H, Ogino T, Harabuchi Y
- Organizer
  The 12th Japan-Korea Joint Meeting of Otorhinolaryngology Head and Neck Surgery
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] New diagnostic and treatment procedures for nasal NK/Tcell lymphoma : Real-time PCR analysis of serum EBV DNA and intra-maxillary arterial chemotherapy with concomit antradiotherapy2008
- Author(s)
  Harabuchi Y, Takahara M, Kishibe K, Ishii M
- Organizer
  The 22nd Congress of the European Rhinologie Society & 27th International Symposium on Infection and Allerfy of the Nose
- Place of Presentation
  Crete, Greece
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Autocrine function of interferon-gamma-inducible protein-10 (IP-10) in nasal NK/T cell lymphoma2008
- Author(s)
  Moriai S, Takahara M, Nagato T, Kishibe K, Harabuchi Y
- Organizer
  The 13th EBV Symposium 2008
- Place of Presentation
  Guangzhou, China
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression and function of LFA-1 and ICAM-1 in nasal NK/T cell lymphoma2008
- Author(s)
  Takahara M, Kishibe K, Moriai S, Ishii H, Harabuchi Y
- Organizer
  The 13th EBV Symposium 2008
- Place of Presentation
  Guangzhou, China
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Co-culture with monocytes enhanced the expression of LMP-1 in cell lines derived from EBV positive NK malignancies2008
- Author(s)
  Ishii H, Takahara M, Harabuchi Y, Klein E
- Organizer
  The 13th EBV Symposium 2008
- Place of Presentation
  Guangzhou,China
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Expression of Metalloelastase in Nasal Natural Killer/T-Cell Lymphoma Cell Lines2008
- Author(s)
  kishibe K, Nagato T, Moriai S, Takahara M, Bandoh N, Harabuchi Y
- Organizer
  The 13th EBV Symposium 2008
- Place of Presentation
  Guangzhou, China
- Data Source
  KAKENHI-PROJECT-20390438
[Presentation] Intra-arterial chemoradiotherapy of neck cancer association nasal NK/T cell lymphoma.2006
- Author(s)
  Yasuaki Harabuchi, et.al
- Organizer
  30^<th> annual meeting of Japan head and neck cancer association
- Place of Presentation
  osaka
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Presentation] 鼻性NK/T細胞リンパ腫における放射線同時併用動注化学療法2006
- Author(s)
  原渕保明
- Organizer
  第30回日本頭頸部癌学会
- Place of Presentation
  大阪
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17390455
[Presentation] C-C chemokine receptor 4 is a remarkable molecule for novel targeted therapy against nasal natural killer/T-cell lymphoma
- Author(s)
  Toshihiro Nagato, Takumi Kumai, Hiroya Kobayashi, Yuki Komabayashi, Seigo Ueda, Kan Kishibe, Miki Takahara, Yasuaki Harabuchi
- Organizer
  16th International Symposium on EBV
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2014-07-16 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] 鼻性NK/T細胞リンパ腫における EBウイルスmicroRNA miR-BART22 の発現と機能解析
- Author(s)
  駒林優樹、岸部　幹、林　達哉、原渕保明
- Organizer
  第38回日本頭頸部癌学会
- Place of Presentation
  東京都江東区
- Year and Date
  2014-06-12 – 2014-06-13
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] Soluble ICAM-1 secretion and its functional role as an autocrine growth factor in nasal NK/T cell lymphoma cells
- Author(s)
  Miki Takahara, Toshihiro Nagato, Yuki Komabayashi, Seigo Ueda, Yasuaki Harabuchi
- Organizer
  16th International Symposium on EBV
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2014-07-16 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] Expression and function of Epstein-Barr virus-encoded microRNAs in nasal natural killer / T-cell lymphoma
- Author(s)
  Yuki Komabayashi, Miki Takahara, Seigo Ueda, Yasuaki Harabuchi
- Organizer
  16th International Symposium on EBV
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2014-07-16 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] Regulation of CDK1 and BIRC5 by EBV-encoded LMP1 in nasal NK/T-cell lymphoma cells
- Author(s)
  Seigo Ueda, Yuki Komabayashi, Miki Takahara, Michele Bernasconi, Norio Shimizu, David Nadal, Yasuaki Harabuchi
- Organizer
  16th International Symposium on EBV
- Place of Presentation
  Brisbane, Australia
- Year and Date
  2014-07-16 – 2014-07-19
- Data Source
  KAKENHI-PROJECT-24390385
[Presentation] 鼻性NK/T細胞リンパ腫におけるEBウイルスmicroRNA BART22の発現と機能解析
- Author(s)
  駒林優樹、岸部　幹、高原　幹、原渕保明
- Organizer
  第62回日本ウイルス学会
- Place of Presentation
  神奈川県横浜市
- Year and Date
  2014-11-10 – 2014-11-12
- Data Source
  KAKENHI-PROJECT-24390385

1. TAKAHARA Miki (50322904)

# of Collaborated Projects: 8 results

# of Collaborated Products: 85 results
2. KOBAYASHI Hiroya (90280867)

# of Collaborated Projects: 7 results

# of Collaborated Products: 30 results
3. KISHIBE Kan (80447101)

# of Collaborated Projects: 6 results

# of Collaborated Products: 66 results
4. NAGATO Toshihiro (80431419)

# of Collaborated Projects: 5 results

# of Collaborated Products: 66 results
5. BANDOH Nobuyuki (60312469)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
6. Kumai Takumi (00596306)

# of Collaborated Projects: 4 results

# of Collaborated Products: 35 results
7. AOZASA Katsuyuki (30115985)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. UEDA Seigo (90447102)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
9. KOMABAYASHI Yuki (40548864)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
10. OGINO Takeshi (00312455)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
11. 大栗敬幸 (70564061)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
12. 大原賢三 (20596308)

# of Collaborated Projects: 2 results

# of Collaborated Products: 14 results
13. KATAYAMA Akihiro (40374805)

# of Collaborated Projects: 1 results

# of Collaborated Products: 20 results
14. HIMI Tetsuo (90181114)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOJYA Sizuo (60161923)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 安部裕介 (90333674)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 本行忠志 (90271569)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 中塚伸一 (90303940)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 星田義彦 (40324777)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 猪原秀典 (00273657)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. 石井秀幸 (90360982)

# of Collaborated Projects: 1 results

# of Collaborated Products: 17 results
22. 野中聡 (50180758)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. 小林吉史 (70225556)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Harabuchi Yasuaki 原渕 保明

HARABUCHI Yasuaki 原渕 保明

原淵 保明 ハラブチ ヤスアキ

Research Projects

Research Products

Co-Researchers

Establishment of novel immunotherapy against nasal NK/T cell lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Biomarkers to select the immune checkpoint inhibitor-responder in head and neck cancer

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Developing novel immunotherapy against nasal NK/T cell lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of novel diagnosis and therapeutic procedures for nasal NK/T-cell lymphoma consists of targeting EBV-associated moleculesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

A foundational study for targeted therapy against EB virus and tumor growth factor in nasal NK/T-cell lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Fundamental investigation aimed at EB virus-targeted therapy for nasal NK/T-cell lymphoma.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Development of New diagnostic methods and treatments against EB virus as a target in nasal NK/T cell lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

鼻腔NK/T細胞リンパ腫発生要因の疫学的解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

反復性扁桃炎・中耳炎に対するペプチドワクチン療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular biologic, immunogenetic, and Epstein-Barr virus studies on nasal NK/T-cell lymphomaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IMMUNOLOGIC, GENETIC AND EPSTEIN-BARR VIROLOGICAL STUDIES OF MALIGNANCIES IN HEAD AND NECK LESIONPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The study of inflammatory and defensive mechanisms in otitis media with effusion.

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

IMMUNOLOGICAL AND EPSTEIN-BARR VIROLOGICAL STUDIES OF LETHAL MIDLINE GRANULOMAPrincipal Investigator

Principal Investigator

Harabuchi Yasuaki 原渕保明

HARABUCHI Yasuaki 原渕保明

原淵保明ハラブチヤスアキ

[Book] 専門医通信鼻性NK/T細胞リンパ腫2012