Egashira Yukari 江頭祐嘉合

… Alternative Names

EGASHIRA Yukari 江頭祐嘉合

江頭祐嘉合エガシラユカリ

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Researcher Number	80213528
Other IDs
External Links
Affiliation (Current)	2025: 千葉大学, 大学院園芸学研究院, 教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 千葉大学, 大学院園芸学研究院, 教授 2018 – 2019: 千葉大学, 大学院園芸学研究科, 教授 2015 – 2016: 千葉大学, 大学院園芸学研究科, 教授 2011 – 2015: 千葉大学, 園芸学研究科, 教授 2012: 千葉大学, 大学院・園芸学研究科, 教授 … More 2008 – 2010: Chiba University, 大学院・園芸学研究科, 教授 2008: 千葉大学, 園芸学研究科, 教授 2007: 千葉大学, 園芸学研究科, 准教授 2007: Chiba University, Faculty of Horticulture, Professor 2005 – 2006: 千葉大学, 園芸学部, 助教授 2002 – 2003: 千葉大学, 園芸学部, 助教授 2001: 千葉大学, 園芸学部, 助手 1995 – 1996: 千葉大学, 園芸学部, 助手 Less
Review Section/Research Field	Principal Investigator Food science / 食品科学・栄養科学 / Basic Section 38050:Food sciences-related Except Principal Investigator Basic Section 41040:Agricultural environmental engineering and agricultural information engineering-related / Agricultural environmental engineering / Boundary agriculture
Keywords	Principal Investigator ナイアシン / トリプトファン / ACMSD / キノリン酸 / ミクログリア / NAD / 炎症 / ピコリン酸 / picolinate / quinolinate … More / rat / tryptophan / ラット / LPS / IDO / 脳 / 神経毒 / 慢性炎症 / グリア細胞 / 転写因子 / IDO1 / ミクログリア細胞 / アミロイドβ / エイコサノイド / linoleic acid / immunity / niacin / マウス / リノール酸 / 生体防御 / ＮＡＤ / ファイトケミカル / SREBP / ホルモン / キヌレニン / モノクローナル抗体 / アミノカルボキシムコン酸セミアルデヒド脱炭酸酵素 / 脱炭酸酵素 / 酵素 / 豚の腎臓 / アミノカルボキシムコン酸セミアルデヒドﾞ脱炭酸酵素 … More Except Principal Investigator 機能性成分 / 培養液低温 / 生育制御 / 環境ストレス / 人工光型植物工場 / 植物工場 / 低培養液温 / 紫外線 / 遺伝子発現 / 生理活性物質 / 環境制御 / 分離・収集 / 回収 / 分離 / 食物繊維 / 機能性物質 / 未利用資源 / バイオマス / 浸漬 / 粉末化 / 乾燥 / 機能性 / 物性 / 構造 / 果皮 / カンキツ / 日長反応 / 光質 / 花芽分化 / 光条件 / 河川水 / 水路堆積物 / 硝酸態窒素 / 環境浄化 Less

トリプトファン代謝鍵酵素と腸内環境を介した脳内炎症制御機構の解明Principal Investigator
- Principal Investigator
  
  江頭祐嘉合
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Chiba University
Regulatory mechanisms of tryptophan metabolic key enzymes protecting brain functions by food componentsPrincipal Investigator
- Principal Investigator
  
  Egashira Yukari
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Chiba University
Development of a high-functional plant production system using secondary biosynthesis control in a plant factory with artificial light
- Principal Investigator
  
  Goto Eiji
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 41040:Agricultural environmental engineering and agricultural information engineering-related
- Research Institution
  Chiba University
A study on mechanism of tryptophan metabolic key enzymes protecting the brain environment by food ingredientsPrincipal Investigator
- Principal Investigator
  
  Egashira Yukari
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Chiba University
Development of efficient collection method for citrus peel as a foodstuff and search of its functionality
- Principal Investigator
  
  OGAWA Yukiharu
- Project Period (FY)
  2012 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Agricultural environmental engineering
- Research Institution
  Chiba University
Study on the regulatory mechanisms of neurodegenelation by tryptophan key enzymesPrincipal Investigator
- Principal Investigator
  
  EGASHIRA Yukari
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Chiba University
The role of tryptophan-niacin key enzymes in brain's immune systemPrincipal Investigator
- Principal Investigator
  
  EGASHIRA Yukari
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Chiba University
Construct the system of purifying eutrophic water by enhancing the functionality of aquatic vegetable, Ipomoea aquatica Forsk
- Principal Investigator
  
  TAKAGAKI Michiko
- Project Period (FY)
  2006 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Boundary agriculture
- Research Institution
  Chiba University
A novel function of tryptophan key enzyme in the brain and its regulation mechanismPrincipal Investigator
- Principal Investigator
  
  EGASHIRA Yukari
- Project Period (FY)
  2005 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Food science
- Research Institution
  Chiba University
The novel function of a key enzyme regulating tryptophan-NAD metabolismPrincipal Investigator
- Principal Investigator
  
  EGASHIRA Yukari
- Project Period (FY)
  2001 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Chiba University
ナイアシン合成の鍵酵素のモノクローナル抗体の作製とcDNAクローニングPrincipal Investigator
- Principal Investigator
  
  江頭祐嘉合
- Project Period (FY)
  1996 – 1997
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Chiba University
トリプトファン・ナイアシン代謝の鍵酵素(ACMS脱炭酸酵素)の精製と性質Principal Investigator
- Principal Investigator
  
  江頭祐嘉合
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  食品科学・栄養科学
- Research Institution
  Chiba University

[Book] Modified Rice Bran Arabinoxylan-Therapeutic Applications in Cancer and Other Diseases- (Edited by S.C.Pak, S.L.Ooi, P.S.Micalos, M.H.Ghoneum)2023
- Author(s)
  Yukari Egashira
- Total Pages
  146
- Publisher
  Springer
- ISBN
  9789811957345
- Data Source
  KAKENHI-PROJECT-21K05420
[Book] 食品学総論（江頭祐嘉合編集）2022
- Author(s)
  江頭祐嘉合
- Total Pages
  335
- Publisher
  理工図書
- Data Source
  KAKENHI-PROJECT-21K05420
[Book] 基礎栄養学（小林謙一編集）2021
- Author(s)
  江頭祐嘉合
- Total Pages
  405
- Publisher
  理工図書
- Data Source
  KAKENHI-PROJECT-21K05420
[Book] ビタミン・バイオファクター総合事典 (日本ビタミン学会編集)2021
- Author(s)
  江頭祐嘉合
- Total Pages
  635
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-21K05420
[Journal Article] ミクログリア細胞におけるトリプトファン・ナイアシン代謝鍵酵素と炎症2023
- Author(s)
  江頭祐嘉合
- Journal Title
  
  ビタミン
  
  Volume: 97 Pages: 419-421
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K05420
[Journal Article] Effect of apigenin on tryptophan metabolic key enzymes expression in lipopolysaccharide-induced microglial cells and its mechanism2023
- Author(s)
  Kurniati Dian、Hirai Shizuka、Egashira Yukari
- Journal Title
  
  Heliyon
  
  Volume: 9 Issue: 1 Pages: e12743-e12743
- DOI
  10.1016/j.heliyon.2022.e12743
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05420
[Journal Article] 野菜およびフィトケミカルの健康機能性2017
- Author(s)
  江頭　祐嘉合
- Journal Title
  
  食品と科学
  
  Volume: 59 Pages: 63-67
- Data Source
  KAKENHI-PROJECT-26450150
[Journal Article] Ferulic acid suppresses expression of tryptophan metabolic key enzyme indoleamine 2, 3-dioxygenase via NFκB and p38 MAPK in　lipopolysaccharide-stimulated microglial cells2017
- Author(s)
  M Koshiguchi, H Komazaki, S Hirai, Y Egashira
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 81 Issue: 5 Pages: 966-971
- DOI
  10.1080/09168451.2016.1274636
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26450150
[Journal Article] Regulation of rat hepaticα-amino-β-carboxymuconate-ε- semialdehyde decarboxylase, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-22014
- Author(s)
  Hiroko Matsuda, Mayumi Sato, Mako Yakushiji, Manami Koshiguchi, Shizuka Hirai, and Yukari Egashira
- Journal Title
  
  Eur.J. Nutr
  
  Volume: 53 Pages: 469-477
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580158
[Journal Article] Regulation of rat hepatic α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and sterol regulatory element-binding protein-2.2014
- Author(s)
  H Matsuda, M Sato, M Yakushiji, M Koshiguchi, S Hirai, Y Egashira
- Journal Title
  
  Eur.J. Nutr.
  
  Volume: 53 Issue: 2 Pages: 469-477
- DOI
  10.1007/s00394-013-0547-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580158
[Journal Article] Effect of dietary phytol on the expression of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism in rats2013
- Author(s)
  Hiroko Matsuda, Ryo-ta Gomi, Shizuka Hirai, Yukari Egashira
- Journal Title
  
  Bioscience, Biotechnology and Biochemistry
  
  Volume: 77
- NAID
  10031190445
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580158
[Journal Article] Effect of dietary phytol on the expression ofα-amino-β-carboxymuconate-ε- semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism in rats2013
- Author(s)
  Hiroko Matsuda, Ryota Gomi, Shizuka Hirai, and Yukari Egashira
- Journal Title
  
  Biosci. Biotech. Biochem
  
  Volume: 77(7) Pages: 1416-1419
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23580158
[Journal Article] 初代培養肝細胞における糖尿病時のトリプトファン異化代謝産物の変動2010
- Author(s)
  佐々木菜穂、真田宏夫、江頭祐嘉合
- Journal Title
  
  アミノ酸研究 4(2)
  
  Pages: 179-183
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] 初代培養肝細胞における糖尿病時のトリプトファン異化代謝産物の変動2010
- Author(s)
  佐々木菜穂, 真田宏夫, 江頭祐嘉合
- Journal Title
  
  アミノ酸研究
  
  Volume: 4 Pages: 179-183
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats2009
- Author(s)
  Naho Sasaki, Yukari Egashira, Hiroo Sanada
- Journal Title
  
  European Journal of Nutrition 48(3)
  
  Pages: 145-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats.2009
- Author(s)
  佐々木菜穂, 江頭祐嘉合, 真田宏夫
- Journal Title
  
  Eur.J.Nutr. 48(3)
  
  Pages: 145-153
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] Production of L-tryptophan-derived catabolites in hepatocytes from streptozotocin-induced diabetic rats2009
- Author(s)
  N Sasaki, Y Egashira, H Sanada
- Journal Title
  
  Eur.J.Nutr. 48巻
  
  Pages: 145-153
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] 抗高脂血症剤とトリプトファン代謝2008
- Author(s)
  飯島穂、佐々木菜穂、真田宏夫、江頭祐嘉合
- Journal Title
  
  アミノ酸研究 2(2)
  
  Pages: 147-150
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] Down-regulation of □-amino-□-carboxymuconate-□-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPAR□2008
- Author(s)
  N. Sasaki, Y. Egashira. H. Sanada
- Journal Title
  
  European Journal of Nutrition 47
  
  Pages: 80-86
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Down-regulation of α-amino-β-carboxymuconate-ε-semialdehydedecarboxylase by polyunsaturated fatty acids in hepatocytesis not mediated by PPARα2008
- Author(s)
  N Sasaki, Y Egashira, H Sanada
- Journal Title
  
  European Journal of Nutrition (in perss)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] 抗高脂血症剤とトリプトファン代謝2008
- Author(s)
  飯島稔、佐々木菜穂、真田宏夫、江頭祐嘉合
- Journal Title
  
  アミノ酸研究 2(2)
  
  Pages: 147-150
- Data Source
  KAKENHI-PROJECT-20580122
[Journal Article] Down-regulation of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase by polyunsaturated fatty acids in hepatocytes is not mediated by PPARα2008
- Author(s)
  N. Sasaki, Y. Egashira, H. Sanada
- Journal Title
  
  European Journal of Nutrition 47
  
  Pages: 80-86
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] 水生野菜エンサイの抗酸化能と季節による総ポリフェノール量の変動2008
- Author(s)
  石淵豊人, 葛西絵美, 藤巻めぐみ, 高垣美智子, 倉内伸幸, 真田宏夫, 江頭祐嘉合
- Journal Title
  
  日本栄養・食糧学会誌 61-2
  
  Pages: 55-55
- Data Source
  KAKENHI-PROJECT-18380190
[Journal Article] Dietary protein level and dietary interaction affect quinqlinic acid concentration in rats.2007
- Author(s)
  Y. Egashira, M. Sato, K. Saito, H. Sanada
- Journal Title
  
  Int. J. Vitam. Nutr. Res. 77
  
  Pages: 142-148
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Dietary protein level and dietary interaction affect quinolinic acid concentration in rats2007
- Author(s)
  Y. Egashira, M. Sato, K. Saito, H. Sanada
- Journal Title
  
  Int. J. Vitam. Nutr. Res 77
  
  Pages: 142-148
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Tryptophan-niacin metabolism in rat with puromycin aminonu cleoside-induced nephrosis.2006
- Author(s)
  Y. Egashira, S. Nagaki, H. Sanada
- Journal Title
  
  Int. J. Vitam. Nutr. Res. 76
  
  Pages: 28-33
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.2006
- Author(s)
  Y Egashira
- Journal Title
  
  Int.J.Vitam.Nutr.Res. 76・3
  
  Pages: 138-146
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic α-amino-β-carboxy muconate-ε-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway2006
- Author(s)
  Y. Egashira, M. Sato, M. Sato, R. Sugawara, A. Tanabe, M. Shin, H. Sanada
- Journal Title
  
  Int. J. Vitam. Nutr. Res 76
  
  Pages: 138-146
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Differential effects of pyrazinamide and clofibrate on gene expression of rat hepatic □-amino-□-carboxymuconate-□-semialdehyde decarboxylase, a key enzyme of the tryptophan-NAD pathway.2006
- Author(s)
  Y. Egashira. M. Sato, M. Sato、 R. Sugawara, A. Tanabe, M. Shin, H. Sanada
- Journal Title
  
  Int. J. Vitam. Nutr. Res. 76
  
  Pages: 138-146
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Tryptophan-niacin metabolism in rat with puromycin aminonucleoside-induced nephrosis2006
- Author(s)
  Y. Egashira, S. Nagaki, H. Sanada
- Journal Title
  
  Int. J. Vitam. Nutr. Res 76
  
  Pages: 28-23
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Puromycin aminonucleoside誘発ネフローゼラットのトリプトファン代謝-腎臓ACMSDの役割-2006
- Author(s)
  江頭祐嘉合、長岐新、真田宏夫
- Journal Title
  
  必須アミノ酸研究 175
  
  Pages: 12-17
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Tryptophan metabolism in rat with puromycin aminonucleoside-induced nephrosis-the role of kidney ACMSD2006
- Author(s)
  Y. Egashira, S. Nagaki, H. Sanada
- Journal Title
  
  Reports of the Research Committee of essential amino acids (Japan) 175
  
  Pages: 12-17
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Journal Article] Tryptophan-niacin metabolism in rat with puromycin aminonucleoside induced nephrosis.
- Author(s)
  Yukari Egashira et al.
- Journal Title
  
  Int.J.Vitam.Nutr.Res. (In Press)
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Alteration of tryptophan-NAD metabolism by nutritional factors and its mechanism2023
- Author(s)
  Yukari Egashira
- Organizer
  国際トリプトファン学会（ISTRY; International Society for Tryptophan Research）オンラインシンポジウム
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] LPS処理ミクログリア細胞におけるニコチンアミドモノヌクレオチド（NMN）のトリプトファン・NAD代謝鍵酵素と炎症に及ぼす影響2023
- Author(s)
  江頭祐嘉合，Dian Kurniati，平井静，Guoqing Xing
- Organizer
  日本ビタミン学会学術大会
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] LPS処理ミクログリア細胞におけるヒスチジンのトリプトファン・ NAD代謝鍵酵素と炎症に及ぼす影響2023
- Author(s)
  松山大治朗，佐藤秀平，平井静，江頭祐嘉合
- Organizer
  日本アミノ酸学会大会
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] 高たんぱく質食によるトリプトファン代謝鍵酵素ACMSD発現調節へのmTORの関与2023
- Author(s)
  佐々木航大，白田茜，西山衿加，稲葉風月，Dian Kurniati，平井静，江頭祐嘉合
- Organizer
  日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] LPS炎症時のマウス脳内トリプトファン・NAD代謝鍵酵素に及ぼす紫蘇フラボノイドの影響2022
- Author(s)
  江頭祐嘉合,平井静,Dian Kurniati
- Organizer
  日本アミノ酸学会
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] Effect of perilla flavonoid apigenin on tryptophan-NAD metabolic key enzymes expression in LPS-stimulated microglial cells and its mechanism2022
- Author(s)
  Yukari Egashira, Dian Kurniati, Shizuka Hirai
- Organizer
  22nd International congress of nutrition（ICN）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] 食品成分が炎症誘導ミクログリア細胞のトリプトファン代謝鍵酵素の発現に及ぼす影響2022
- Author(s)
  江頭祐嘉合,平井静,Dian Kurniati,越口愛美
- Organizer
  日本栄養食糧学会大会講演要旨集
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] トリプトファン・NAD代謝酵鍵素ACMSDと炎症との関連と食品成分の作用2022
- Author(s)
  江頭祐嘉合,平井静,Dian Kurniati,越口愛美
- Organizer
  JSTRY2022（日本トリプトファン研究会）
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] ラットにおけるトリプトファン・NAD代謝鍵酵素ACMSDの高たんぱく質食による発現調節2021
- Author(s)
  江頭祐嘉合, 西山衿加, 稲葉風月, Dian Kurniati, 平井静
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-21K05420
[Presentation] LPS誘発炎症ミクログリア細胞のトリプトファン代謝鍵酵素に及ぼすケルセチンの影響と作用機序2016
- Author(s)
  江頭祐嘉合，越口愛美，高内健志，平井静
- Organizer
  日本トリプトファン研究会
- Place of Presentation
  東京農業大学 (東京都、世田谷区）
- Year and Date
  2016-12-10
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] ケルセチンは NFκB 経路を介して LPS 誘発炎症ミクログリア細胞におけるトリプトファン代謝鍵酵素を抑制する2016
- Author(s)
  江頭祐嘉合，高内健志，越口愛美，平井静
- Organizer
  日本アミノ酸学会
- Place of Presentation
  東京大学 (東京都、文京区）
- Year and Date
  2016-09-12
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] ACMSD発現調節機構におけるHNF4αおよびPGC1αの役割2016
- Author(s)
  越口愛美，平井静，江頭祐嘉合
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  武庫川女子大（兵庫県、西宮市）
- Year and Date
  2016-05-14
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] Regulation of ACMSD, a key enzyme in the tryptophan-NAD pathway, by diet and hormones2015
- Author(s)
  江頭祐嘉合
- Organizer
  国際トリプトファン学会
- Place of Presentation
  ミシガン州立大学（ミシガン州・米国）
- Year and Date
  2015-09-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] Regulation　of rat hepatic ACMSD, a key enzyme in the tryptophan-NAD pathway, by dietary cholesterol and SREBP-22015
- Author(s)
  松田寛子、佐藤麻弓、薬師寺真子、越口愛美、平井静、江頭祐嘉合
- Organizer
  国際トリプトファン学会
- Place of Presentation
  ミシガン州立大学（ミシガン州・米国）
- Year and Date
  2015-09-16
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] エネルギー制限によるトリプトファン代謝鍵酵素ACMSD発現調節機構の解明2015
- Author(s)
  杉本光季、越口愛美、平井静、江頭祐嘉合
- Organizer
  日本アミノ酸学会
- Place of Presentation
  滋賀県立大学（彦根市・滋賀県）
- Year and Date
  2015-10-23
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] 脳炎症時のトリプトファン代謝鍵酵素に及ぼすフィトケミカルの影響2014
- Author(s)
  江頭祐嘉合，倉部隼，越口愛美，駒崎仁，平井静
- Organizer
  第36回日本トリプトファン研究会学術集会
- Place of Presentation
  旭川医科大学（旭川）
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] 炎症誘導ミクログリア細胞におけるフェルラ酸のトリプトファン代謝鍵酵素IDO の発現抑制作用2014
- Author(s)
  越口愛美、駒崎仁、平井静、江頭祐嘉合
- Organizer
  第68回日本栄養食糧学会
- Place of Presentation
  北海道大学（札幌）
- Year and Date
  2014-06-01
- Data Source
  KAKENHI-PROJECT-26450150
[Presentation] Modulatory effect of ferulic acid on LPS-induced indoleamine 2, 3-deoxygenase (IDO) expression in microglia.2013
- Author(s)
  M Koshiguch, H Komazaki, M Otsuka, S Hirai, Y Egashira
- Organizer
  国際栄養学会議
- Place of Presentation
  グラナダ（スペイン）
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] Modulatory effect of ferulic acid on LPS-induced indoleamine 2, 3-deoxygenase (IDO) expression in microglia2013
- Author(s)
  Manami Koshiguchi, Hitoshi Komazaki, Masako Otsuka, Shizuka Hirai, Yukari Egashira
- Organizer
  国際栄養学会議
- Place of Presentation
  グラナダ(スペイン)
- Year and Date
  2013-09-19
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] 多価不飽和脂肪酸リノール酸によるトリプトファン代謝鍵酵素ACMSDの活性抑制機構に関する研究2013
- Author(s)
  松田寛子・薬師寺真子・中込友梨・越口愛美・平井静・江頭祐嘉合
- Organizer
  日本栄養食糧学会
- Place of Presentation
  名古屋大学
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] 多価不飽和脂肪酸リノール酸によるトリプトファン代謝鍵酵素ACMSDの活性抑制機構に関する研究2013
- Author(s)
  松田寛子、薬師寺真子、中込友梨、越口愛美、平井静、江頭祐嘉合
- Organizer
  日本栄養・食糧学会大会
- Place of Presentation
  名古屋大学(愛知県)
- Year and Date
  2013-05-25
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] Effect of dietary phytol on the expression of α-amino-β-carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism in rats2012
- Author(s)
  Hiroko Matsuda, Ryo-ta Gomi, Shizuka Hirai, Yukari Egashira
- Organizer
  国際トリプトファン学会
- Place of Presentation
  オーストラリア（シドニー）
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] The study on relationship between ACMSD activity and cholesterol metabolism in rats2012
- Author(s)
  Mayumi Sato, Hiroko Matsuda, Mako Yakushiji, Shizuka Hirai, Yukari Egashira
- Organizer
  国際トリプトファン学会
- Place of Presentation
  シドニー(オーストラリア)
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] A mechanism for the production of quinolinic acid　by　dietary components or medicine2012
- Author(s)
  Yukari Egashira, Naho Sasaki, Kuniaki Saito, Minori Iijima
- Organizer
  国際トリプトファン学会
- Place of Presentation
  オーストラリア（シドニー）
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] Effect of dietary phytol on the expression ofα-amino-β- carboxymuconate-ε-semialdehyde decarboxylase, a key enzyme of tryptophan-niacin metabolism in rats2012
- Author(s)
  Hiroko Matsuda, Ryo-ta Gomi, Shizuka Hirai, Yukari Egashira
- Organizer
  国際トリプトファン学会
- Place of Presentation
  シドニー(オーストラリア)
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] The study on relationship between ACMSD activity and cholesterol metabolism in rats2012
- Author(s)
  Mayumi Sato, Hiroko Matsuda, Mako Yakushiji, Shizuka Hirai, Yukari Egashira
- Organizer
  国際トリプトファン学会
- Place of Presentation
  オーストラリア（シドニー）
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] A mechanism for the production of quinolinic acid by dietary components or medicine2012
- Author(s)
  Yukari Egashira, Naho Sasaki, Kuniaki Saito,Minori Iijima
- Organizer
  国際トリプトファン学会
- Place of Presentation
  シドニー(オーストラリア)
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] 食品成分フィトールがトリプトファン・ナイアシン代謝鍵酵素の遺伝子発現に及ぼす影響2011
- Author(s)
  松田寛子、平井静、江頭祐嘉合
- Organizer
  日本栄養・食糧学会大会
- Place of Presentation
  お茶ノ水女子大学(東京都)
- Year and Date
  2011-05-15
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] 高コレステロール負荷がラットにおけるトリプトファン代謝系の主要酵素活性と遺伝子発現に及ぼす影響2011
- Author(s)
  佐藤麻弓、五味亮太、松田寛子、薬師寺真子、平井静、江頭祐嘉合
- Organizer
  日本トリプトファン研究会
- Place of Presentation
  東邦大学(千葉県)
- Year and Date
  2011-12-04
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] 食品成分フィトールによるトリプトファン・ナイアシン代謝酵素の遺伝子発現調節機構2010
- Author(s)
  松田寛子, 五味亮太, 平井静, 江頭祐嘉合
- Organizer
  日本トリプトファン研究会第32回学術集会
- Place of Presentation
  滋賀県立大学
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] 食品成分によるトリプトファン・ナイアシン代謝酵素の発現調節機構に関する研究2010
- Author(s)
  松田寛子、五味亮太、平井静、江頭祐嘉合
- Organizer
  日本農芸化学会関東支部2010年度支部大会
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] In Vivoとin vitroにおける糖尿病時のトリプトファン代謝産物の変動2010
- Author(s)
  佐々木菜穂, 真田宏夫, 江頭祐嘉合
- Organizer
  日本トリプトファン研究会第32回学術集会
- Place of Presentation
  滋賀県立大学
- Year and Date
  2010-12-05
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] 食品成分によるトリプトファン・ナイアシン代謝酵素の発現調節機構に関する研究2010
- Author(s)
  松田寛子, 五味亮太, 平井静, 江頭祐嘉合
- Organizer
  日本農芸化学会関東支部2010年度支部大会
- Place of Presentation
  千葉大学園芸学部
- Year and Date
  2010-10-09
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] In vivoとin vitroにおける糖尿病時のトリプトファン代謝産物の変動2010
- Author(s)
  佐々木菜穂、真田宏夫、江頭祐嘉合
- Organizer
  日本トリプトファン研究会第32回学術集会
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] 食品成分フィトールによるトリプトファン・ナイアシン代謝酵素の遺伝子発現調節機構2010
- Author(s)
  松田寛子、五味亮太、平井静、江頭祐嘉合
- Organizer
  日本トリプトファン研究会第32回学術集会
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] Effect of dehydroisoandrosterone on tryptophan metabolism and quinolinic acid production in rats2009
- Author(s)
  Yukari Egashira, Minako Okamura, Hiroo Sanada
- Organizer
  国際栄養学会議
- Place of Presentation
  B I TEK(バンコク(タイ)
- Year and Date
  2009-10-06
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] Dietary interaction and hormones affect serum quinolinic acid production in rats, accompanied with alteration of ACMSD activity and its mRNA expression.2009
- Author(s)
  江頭祐嘉合, 真田宏夫, 齋藤邦明, 岡村美那子
- Organizer
  国際トリプトファン学会
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] Dietary interaction and hormones affect serum quinolinic acid production in rats, accompanied with alteration of ACMSD activity and its mRNA expression.2009
- Author(s)
  Yukari Egashira, Hiroo Sanada, Kuniaki Saito, Minako Okamura
- Organizer
  国際トリプトファン学会
- Place of Presentation
  フィレンツェ大学(イタリア)
- Year and Date
  2009-07-10
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] Effect of dehydroisoandrosterone on tryptophan metabolism and quinolinic acid production in rats.2009
- Author(s)
  江頭祐嘉合, 岡村美那子, 真田宏夫
- Organizer
  国際栄養学会議
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] 水生野菜エンサイの抗酸化能と季節による総ポリフェノール量の変動2008
- Author(s)
  石淵豊人, 葛西絵美, 藤巻めぐみ, 高垣美智子, 倉内伸幸, 真田宏夫, 江頭祐嘉合
- Organizer
  日本栄養・食糧学会誌
- Place of Presentation
  (61 : 2, 55)
- Data Source
  KAKENHI-PROJECT-18380190
[Presentation] デヒドロイソアンドロステロンによるラットの血中キノリン酸量への影響2008
- Author(s)
  岡村美那子、齋藤邦明、真田宏夫、江頭祐嘉合
- Organizer
  第62回日本栄養食糧学会大会
- Data Source
  KAKENHI-PROJECT-20580122
[Presentation] Effects of various dietary phytochemicals on2-amino-3-carboxymuconate-6-semialdehyde decarboxylaseactivitX a key enzyme of tryptophan-niacin metabolism,in rats2007
- Author(s)
  Y Egashira
- Organizer
  アジア栄養学会議
- Place of Presentation
  台北(台湾)
- Year and Date
  2007-09-10
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Effects of various dietary phytochemicals on 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase activity, a key enzyme of typtophan-niacin metabolism, in rats2007
- Author(s)
  Y. Egashira, J. Kurabe, H. Sanada
- Organizer
  10th Asian Congress of Nutrition
- Place of Presentation
  Taipei
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Effects of various dietary phytochemicals on 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase activity, a keyenzyme of tryptophan-niacin metabolism, in rats2007
- Author(s)
  Y. Egashira, Jun Kurabe, Hiroo Sanada
- Organizer
  10th Asian Congress of Nutrition
- Place of Presentation
  台北
- Year and Date
  2007-09-10
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Dietary fat and peroxisome-proliferators affect production of quinolinate in rats, accompanied with suppression of gene expression of ACMSD2006
- Author(s)
  Y. Egashira, et. al.
- Organizer
  11th International meeting on tryptophan research
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Down-regulation of ACMSD by polyunsaturated fatty acids in hepatocytes is not mediated by PPAR□.2006
- Author(s)
  N. Sasaki, Y. Egashira、 H. Sanada
- Organizer
  11th International meeting on tryptophan research
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Down-regulation of ACMSD by polyunsaturated fatty acids in hepatocytes is not mediated by PPARα2006
- Author(s)
  N. Sasaki, Y. Egashira, H. Sanada
- Organizer
  llth International meeting on tryptophan research
- Place of Presentation
  Tokyo
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Dietary fat and peroxisome-proliferators affect production of quinolinate in rats, accompanied with suppression. of gene expression of ACMSD.2006
- Author(s)
  Y. Egashira et al.
- Organizer
  11th International meeting on tryptophan research
- Place of Presentation
  東京
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Effects of dietary fat and protein on quinolinic acid production in rats.2005
- Author(s)
  Y. Egashira et al.
- Organizer
  18th International congress of Nutrition
- Place of Presentation
  南アフリカ
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] Effects of dietary fat and protein on quinolinic acid production in rats2005
- Author(s)
  Y. Egashira, et. al.
- Organizer
  18th International congress of Nutrition
- Place of Presentation
  South Africa
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-17580105
[Presentation] 高コレステロール負荷がラットにおけるトリプトファン代謝系の主要酵素活性と遺伝子発現に及ぼす影響
- Author(s)
  佐藤麻弓、五味亮太、松田寛子、薬師寺真子、平井静、江頭祐嘉合
- Organizer
  日本トリプトファン研究会
- Place of Presentation
  東邦大学薬学部
- Data Source
  KAKENHI-PROJECT-23580158
[Presentation] 食品成分フィトールがトリプトファン・ナイアシン代謝鍵酵素の遺伝子発現に及ぼす影響
- Author(s)
  松田寛子、平井静、江頭祐嘉合
- Organizer
  日本栄養・食糧学会
- Place of Presentation
  お茶の水女子大学
- Data Source
  KAKENHI-PROJECT-23580158

1. MARUO Toru (20143266)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. Hirai Shizuka (90432343)

# of Collaborated Projects: 2 results

# of Collaborated Products: 8 results
3. SANADA Hiroo (60196293)

# of Collaborated Projects: 2 results

# of Collaborated Products: 15 results
4. TAKAGAKI Michiko (00206715)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. OZAWA Kiyoshi (40360391)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. KURAUCHI Nobuyuki (00256835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. OGAWA Yukiharu (00373126)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Hikida Yoshio (50127908)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Yamamoto Nami (20351934)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. Goto Eiji (00186884)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 加川夏子 (60467686)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 吉田英生 (40729852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. KOSHIGUCHI Manami

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results

Egashira Yukari 江頭 祐嘉合

EGASHIRA Yukari 江頭 祐嘉合

江頭 祐嘉合 エガシラ ユカリ

Research Projects

Research Products

Co-Researchers

トリプトファン代謝鍵酵素と腸内環境を介した脳内炎症制御機構の解明Principal Investigator

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Research Institution

Regulatory mechanisms of tryptophan metabolic key enzymes protecting brain functions by food componentsPrincipal Investigator

Principal Investigator

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Review Section

Research Institution

Development of a high-functional plant production system using secondary biosynthesis control in a plant factory with artificial light

Principal Investigator

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Review Section

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A study on mechanism of tryptophan metabolic key enzymes protecting the brain environment by food ingredientsPrincipal Investigator

Principal Investigator

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Development of efficient collection method for citrus peel as a foodstuff and search of its functionality

Principal Investigator

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Research Institution

Study on the regulatory mechanisms of neurodegenelation by tryptophan key enzymesPrincipal Investigator

Principal Investigator

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The role of tryptophan-niacin key enzymes in brain's immune systemPrincipal Investigator

Principal Investigator

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Construct the system of purifying eutrophic water by enhancing the functionality of aquatic vegetable, Ipomoea aquatica Forsk

Principal Investigator

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Research Institution

A novel function of tryptophan key enzyme in the brain and its regulation mechanismPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Institution

The novel function of a key enzyme regulating tryptophan-NAD metabolismPrincipal Investigator

Principal Investigator

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Research Institution

ナイアシン合成の鍵酵素のモノクローナル抗体の作製とcDNAクローニングPrincipal Investigator

Principal Investigator

Project Period (FY)

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Research Field

Research Institution

トリプトファン・ナイアシン代謝の鍵酵素(ACMS脱炭酸酵素)の精製と性質Principal Investigator

Principal Investigator

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Research Institution

[Book] Modified Rice Bran Arabinoxylan-Therapeutic Applications in Cancer and Other Diseases- (Edited by S.C.Pak, S.L.Ooi, P.S.Micalos, M.H.Ghoneum)2023

Author(s)

Egashira Yukari 江頭祐嘉合

EGASHIRA Yukari 江頭祐嘉合

江頭祐嘉合エガシラユカリ

[Journal Article] ミクログリア細胞におけるトリプトファン・ナイアシン代謝鍵酵素と炎症2023

[Journal Article] Ferulic acid suppresses expression of tryptophan metabolic key enzyme indoleamine 2, 3-dioxygenase via NFκB and p38 MAPK in　lipopolysaccharide-stimulated microglial cells2017