NAGANO Yutaka 長野豊

… Alternative Names

永野豊ナカ゛ノユタカ

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Researcher Number	80228048
Other IDs
External Links
Affiliation (based on the past Project Information) *help	2012 – 2013: 大阪歯科大学, 歯学部, 講師(非常勤) 2007 – 2011: Osaka Dental University, 歯学部, 講師 2008: 大阪歯科大, 歯学部, 講師 1997 – 2003: 大阪歯科大学, 歯学部, 講師 1992: Kyoto University, Dept. Geriatric Medicine Scientist., 医学部老年科, 助手 1990 – 1992: 京都大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Social dentistry / 病態科学系歯学(含放射線系歯学) Except Principal Investigator 病態科学系歯学(含放射線系歯学) / Circulatory organs internal medicine / 内分泌・代謝学 / Periodontal dentistry / 内科学一般 / General medical chemistry / Pathobiological dentistry/Dental radiology
Keywords	Principal Investigator 歯周病 / 歯周炎 / メタボリックシンドローム / Chronic Inflammation / Endothelial Cell / Macrophage / Periodontitis / Atherosclerosis / Fractalkine / 内皮細胞 … More / 慢性炎症 / 血管内皮細胞 / マクロファージ / 動脈硬化症 / フラクタルカイン / 酸化LDL / バイオマーカー / 社会医学 / シグナル伝達 / メタボリックシンドローム / 歯学 / 内科 / 社会歯学 … More Except Principal Investigator 動脈硬化 / マクロファ-ジ / MCP-1 / ICAM-1 / マクロファージ / phospholipase C / NK細胞 / Macrophage / 歯周病 / RANKL / NK cell / Periodontitis / Fractalkine / IL-2 / T細胞 / preconditioning / alcohol / reperfusion / ischemia / protein kinase C / adenosine / モルモット / Ischemic preconditioning / 心筋虚血 / アルコール / CD2 / LDL receptor / LDL受容体 / 線維芽細胞 / Oxidized LDL receptor / Oxidized LDL / 酸化HDL / 酸化LDL受容体 / 酸化LDL / 11β-HSD1 / メタボリックシンドローム / シグナル伝達 / guineapig / high enegy phosphate / reactie oxygen species / ultrastructure / oxygen free radical / エネルギー代謝 / Vascular endothelial cell / Monocyte / T cell / フィブロネクチン / インテグリン / 慢性辺縁性歯周炎 / CX_3CR1 / フラクタルカイン / THP-1細胞 / 血管内皮細胞 / 単球 / fractalkine / 辺縁性歯周炎 / Chemokine / Extracellular matrix / Adhesion molecule / Osteoblast / T cell activation / 線維芽細胞E11細胞 / PHA刺激T細胞 / ケモカイン / 細胞外マトリックス蛋白 / 細胞接着 / 歯周炎 / ラット / 再灌流 / PI3-kinase / adapter proteins / tyrosine kinase / cytotoxicity / signal pathway / NK cells / PI 3キナーゼ / PI3-キナーゼ / アダプター蛋白 / チロシンキナーゼ / 抗腫瘍活性 / Probucol / Hepatocyte / HMG-CoA Reductase / WHHL-rabbit / プロブコ-ル / HMG-CoA還元酵素 / プロブコール / 肝細胞 / HMG-C_0A還元酵素 / WHHL-ウサギ / protein engineering / human genome / antioxidant / modified LDL / Cholesterol / Scavenger receptor / Atherosclerosis / LDL / コレステロ-ル / 泡沫細胞 / スカベンジャ受容体 / プロモーター / 遺伝子構造 / 抗酸化剤 / コラーゲン / ラジカル反応 / コレステロール / スカベンジャー受容体 / Kuffer cell / Acetyl LDL receptor / Oxidized HDL / 走化因子 / クッパー細胞 / アセチルLDL受容体 / WHHL rabbit / fibroblast / macrophage / beta-VLDL / WHHLウサギ / 受容体 / βVLDL / B-VLDL / ワタナベウサギ / β-VLDL / Lyso-phosphatidyl-choline / 家族性高コレステロ-ル血症 / 粥状動脈硬化 / 平滑筋細胞 / モノクロナ-ル抗体 / HDL / アポAーI / リゾフォスファチジルコリン / 虚血性心疾患 / 動脈硬化症 / グルココルチコイド / 内科 / 歯学 / メタボリックシンドローム Less

Establishment of biomarkers that reflect periodontal conditionPrincipal Investigator
- Principal Investigator
  
  NAGANO Yutaka
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Osaka Dental University
The role of 11β-HSD1, an intracellular glucocorticoid-activating enzyme, in periodontal disease
- Principal Investigator
  
  SAWAI Hirofumi
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Pathobiological dentistry/Dental radiology
- Research Institution
  Osaka Dental University
The role of periodontal disease in formation of atherosclerotic lesion
- Principal Investigator
  
  DOMAE Naochika
- Project Period (FY)
  2010 – 2012
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
Studies on the etiological relationship between periodontitis and life-style related diseases
- Principal Investigator
  
  DOMAE Naochika
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Periodontal dentistry
- Research Institution
  Osaka Dental University
Elucidation of the relevance between oral health and common systemic diseases -an approach for early detection and treatment of periodontitis-Principal Investigator
- Principal Investigator
  
  NAGANO Yutaka
- Project Period (FY)
  2007 – 2009
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Social dentistry
- Research Institution
  Osaka Dental University
Elucidation of the role of fractalkine in chronic inflammatory diseases -An approach for its clinical applicationPrincipal Investigator
- Principal Investigator
  
  NAGANO Yutaka
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University
The roles of interaction between adhesion molecules, chemokines and vascular endothelial cells in the pathogenesis of periodontitis
- Principal Investigator
  
  DOMAE Naochika
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University
Signal Transduction in the Cardioprotective Effect of Light Alcohol and its clinical application for ischemic preconditioning
- Principal Investigator
  
  MIYAMAE Masami
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka Dental University
Signal Transduction in the Cardioprotective Effect of Alcohol
- Principal Investigator
  
  MIYAMAE Masami
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Circulatory organs internal medicine
- Research Institution
  Osaka Dental University
The role of adhesion molecules and cytokines in chronic periodontitis
- Principal Investigator
  
  DOMAE Naochika
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University
CD2-mediated signal pathway in NK cell activation
- Principal Investigator
  
  UMEHARA Hisanori
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  病態科学系歯学(含放射線系歯学)
- Research Institution
  Osaka Dental University
Cell and molecular biological approaches to atherosclerosis in an animal model for familial hypercholesterolemia.
- Principal Investigator
  
  KITA Toru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (A)
- Research Field
  
  内分泌・代謝学
- Research Institution
  KYOTO UNIVERSITY
Molecular biology of macrophage scavenger receptors and modified LDL;
- Principal Investigator
  
  KODAMA Tatsuhiko
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内科学一般
- Research Institution
  UNIVERSITY OF TOKYO
Establishment of a new antiatherosclerotic drug and its screening methods using an animal model.
- Principal Investigator
  
  KITA Toru
- Project Period (FY)
  1991 – 1992
- Research Category
  
  Grant-in-Aid for Developmental Scientific Research (B)
- Research Field
  
  内分泌・代謝学
- Research Institution
  KYOTO UNIVERSITY
Studies on the initiation of atherosclerosis
- Principal Investigator
  
  KITA Toru
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for international Scientific Research
- Research Institution
  KYOTO UNIVERSITY
Purification and structure determination of P-VLDL receptor
- Principal Investigator
  
  MURAKAMI Motonobu
- Project Period (FY)
  1990 – 1992
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  General medical chemistry
- Research Institution
  KYOTO UNIVERSITY

All 2013 2012 2011 2009 2008 2007

All Journal Article Presentation Book

[Book] 新臨床栄養学(増補版)2011
- Author(s)
  長野豊
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-22592323
[Book] 動脈硬化. 臨床分子細胞生物学2009
- Author(s)
  長野豊
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19592420
[Book] 臨床分子細胞生物学2009
- Author(s)
  長野豊
- Total Pages
  294
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-19592420
[Book] 酸化ストレスと心血管病2007
- Author(s)
  長野豊
- Total Pages
  294
- Publisher
  日本医学出版
- Data Source
  KAKENHI-PROJECT-19592420
[Book] 新臨床栄養学2007
- Author(s)
  長野豊
- Total Pages
  618
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-19592420
[Book] プロブコール. 酸化ストレスと心血管病2007
- Author(s)
  長野豊
- Publisher
  東京:日本医学出版
- Data Source
  KAKENHI-PROJECT-19592420
[Book] 高脂血症・動脈硬化. 新臨床栄養学2007
- Author(s)
  長野豊
- Publisher
  東京:医学書院
- Data Source
  KAKENHI-PROJECT-19592420
[Journal Article] Involvement of 11β-HSD1 in metabolic syndrome and periodontal disease2013
- Author(s)
  Shiraishi M, Sawai H, Nagano Y, Ueda M, Umeda M
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 47巻 Pages: 7-10
- NAID
  110009603273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23593113
[Journal Article] Involvement of 11β-HSD1 in metabolic syndrome and periodontal disease2013
- Author(s)
  Shiraishi M, Sawai H, Nagano Y, Ueda M, Umeda M.
- Journal Title
  
  Journal of Osaka Dental University
  
  Volume: 47 Pages: 7-10
- NAID
  110009603273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592105
[Journal Article] Involvement of 11β-HSD1 in metabolic syndrome and periodontal disease2013
- Author(s)
  Shiraishi M, Sawai H, Nagano Y, Ueda M, Umeda M.
- Journal Title
  
  Journal of Osaka Dental University
  
  Volume: 47 Pages: 7-10
- NAID
  110009603273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592323
[Journal Article] Involvement of 11β-HSD1 in metabolic syndrome and periodontal disease2013
- Author(s)
  Masanori Shiraishi、Hirofumi Sawai、 Yutaka Nagano、Masatoshi Ueda、Makoto Umeda
- Journal Title
  
  Journalof Osaka Dental University
  
  Volume: 47 Pages: 7-10
- NAID
  110009603273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592105
[Journal Article] Involvement of 11 β -HSD1 in metabolic syndrome and periodontal disease.2013
- Author(s)
  Shiraishi M, Sawai H, Nagano Y, Ueda M,Umeda M.
- Journal Title
  
  J Osaka Dent Univ
  
  Volume: 47 Pages: 7-10
- NAID
  110009603273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592323
[Journal Article] A low ratio of high molecular weight adiponectin to total adiponectin associates with periodontal status in middle-aged men2011
- Author(s)
  Yutaka Nagano、Kumiko Arishiro、Masako Uene 、 Tatsuro Miyake 、 Masaki Kambara 、 Yasuhiro Notohara、Masanori Shiraishi、 Masatoshi Ueda、Naochika Domae
- Journal Title
  
  Biomarkers
  
  Volume: 16 Issue: 2 Pages: 106-111
- DOI
  10.3109/1354750x.2010.533286
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22592105, KAKENHI-PROJECT-22592323, KAKENHI-PROJECT-23593113
[Journal Article] Induction of osteoprotegerin mRNA during differentiation of monocytes into macrophages.2009
- Author(s)
  NOTOHARA Y, NAGANO Y, DOMAE N, UEDA M.
- Journal Title
  
  J Osaka Dent Univ 43
  
  Pages: 37-42
- NAID
  110007160621
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592420
[Journal Article] Emdogain stimulates matrix degra dation by osteoblasts2008
- Author(s)
  GODA S, INOUE H, KANESHITA Y, NAGANO Y, IKEO T, IIDA J, DOMAE N
- Journal Title
  
  J Dent Res 87
  
  Pages: 782-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592398
[Journal Article] Emdogain stimulates matrix degradation by osteoblasts.2008
- Author(s)
  GODA S, INOUE H, KANESHITA Y, NAGANO Y, IKEO T, IIDA J, DOMAE N.
- Journal Title
  
  J Dent Res 87(8)
  
  Pages: 782-787
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592420
[Presentation] Involvement of 11β- HSD1 in metabolic syndrome and periodontal disease2012
- Author(s)
  Shiraishi M, Sawai H, Nagano Y, Ueda M, Umeda M
- Organizer
  The 98^t h Annual Meeting of American Academy of Periodontology in collaboration with the Japanese Society of Periodontology
- Place of Presentation
  Los Angeles, USA
- Year and Date
  2012-10-01
- Data Source
  KAKENHI-PROJECT-23593113
[Presentation] 歯周病におけるメタボリックシンドローム関連酵素11β-HSD1の関与2012
- Author(s)
  白石真教,澤井宏文,長野豊,能登原靖宏,居波薫,吉田博昭,益崎裕章,堂前尚親,上田雅俊,梅田誠
- Organizer
  日本歯周病学会2012秋季学術大会(第55回)
- Place of Presentation
  つくば国際会議場(つくば市)
- Year and Date
  2012-09-23
- Data Source
  KAKENHI-PROJECT-23593113
[Presentation] Systemic effects of non-surgical treatment of periodontitis.2012
- Author(s)
  Nagano Y.
- Organizer
  The XVI International Symposium on Atherosclerosis
- Place of Presentation
  Sydney, Australia
- Data Source
  KAKENHI-PROJECT-23593113
[Presentation] Systemic effects of non-surgical treatment of periodontitis2012
- Author(s)
  Nagano Y, Notohara Y, Arishiro K, Shiraishi M, Ueda M, Domae N
- Organizer
  The XVI international symposium on atherosclerosis
- Place of Presentation
  Sydney, Australia
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-23593113
[Presentation] Systemic effects of non-surgical treatment of periodontitis.2012
- Author(s)
  Nagano Y.
- Organizer
  The XVI international symposium on atherosclerosis
- Place of Presentation
  Sydney(Australia)
- Year and Date
  2012-03-28
- Data Source
  KAKENHI-PROJECT-22592323
[Presentation] Serum MDA-LDL level is elevated in periodontitis patients and is reduced by standard periodontal treatment2011
- Author(s)
  Shiraishi M, Nagano Y, Notohara Y, Arishiro K, Ueda M, Domae N
- Organizer
  第43回日本動脈硬化学会総会・学術集会
- Place of Presentation
  ロイトン札幌(札幌市)
- Year and Date
  2011-07-15
- Data Source
  KAKENHI-PROJECT-23593113
[Presentation] 歯周病患者における血清MDA-LDL濃度の上昇と歯周治療による改善2011
- Author(s)
  白石真教,長野豊,能登原靖宏,有城久美子,堂前尚親,上田雅俊
- Organizer
  日本歯周病学会2011秋季学術大会(第54回)
- Place of Presentation
  海峡メッセ下関(山口市)
- Year and Date
  2011-09-24
- Data Source
  KAKENHI-PROJECT-23593113
[Presentation] Osteoprotegerin is induced during differentiation of monocytes2008
- Author(s)
  NOTOHARA Y, NAGANO Y, DOMAE N, UEDA M
- Organizer
  The AAP 94^<th> Annual Meeting
- Place of Presentation
  Seattle
- Year and Date
  2008-09-08
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] 単球系細胞のマクロファージ化に伴うosteoprogerin mRNAの誘導2008
- Author(s)
  能登原靖宏,長野豊,堂前尚親,上田雅俊
- Organizer
  第516回大阪歯科学会
- Place of Presentation
  大阪府
- Year and Date
  2008-12-13
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] 動脈硬化の危険因子と歯周状態との関連2008
- Author(s)
  長野豊, 他
- Organizer
  第40回日本動脈硬化学会総会
- Place of Presentation
  つくば国際会議場(茨城県)
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19592420
[Presentation] 動脈硬化の危険因子と歯周状態との関連2008
- Author(s)
  長野豊
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  茨城県
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19592420
[Presentation] THP-1細胞のマクロファージ化に伴うosteoprotegerin mRNAの誘導2008
- Author(s)
  能登原靖宏,長野豊,堂前尚親,上田雅俊
- Organizer
  .日本歯周病学会2008春季学術大会(第51回)
- Place of Presentation
  埼玉県
- Year and Date
  2008-04-25
- Data Source
  KAKENHI-PROJECT-19592398
[Presentation] 動脈硬化の危険因子と歯周状態との関連2008
- Author(s)
  長野豊,有城久美子,藥師寺健太郎,能登原靖宏,上田雅俊, 三宅達郎,神原正樹,堂前尚親
- Organizer
  第40回日本動脈硬化学会総会・学術集会
- Place of Presentation
  茨城県
- Year and Date
  2008-07-10
- Data Source
  KAKENHI-PROJECT-19592398

1. DOMAE Naochika (60115889)

# of Collaborated Projects: 11 results

# of Collaborated Products: 12 results
2. MIYAMAE Masami (20298821)

# of Collaborated Projects: 5 results

# of Collaborated Products: 0 results
3. MASAKI Kambara (90103085)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
4. MIYAKE Taturou (40200141)

# of Collaborated Projects: 4 results

# of Collaborated Products: 1 results
5. KITA Toru (60161460)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
6. UMEHARA Hisanori (70247881)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. SAWAI Hirofumi (40298823)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
8. NOTOHARA Yasuhiro (10548324)

# of Collaborated Projects: 3 results

# of Collaborated Products: 5 results
9. MURAKAMI Motonobu (10157761)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
10. MATSUMOTO Mituhiro (20229579)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
11. YOHSIOKA Hideyuki (30231690)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. UEDA Masatoshi (00067117)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
13. GODA Seiji (70351476)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
14. ARISHIRO Kumiko (20460769)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
15. IMAI Hisao (80067024)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
16. CHAIT Alan

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
17. INOUE Hiroshi (10330143)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
18. MASUZAKI Hiroaki (00291899)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. INAMI Kaoru (40548327)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. KANEDA Kazuhiro (90533886)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
21. ARAI Hidenori (60232021)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. KODAMA Tatsuhiko (90170266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
23. DOI Takefumi (00211409)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
24. MORIKUNI Tadahiro (60098027)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
25. FUKUSHIMA Hisanori (50103099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
26. 成宮周 (70144350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
27. NAGANO Hiroyuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
28. SADAHIRO Ryuhzou

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
29. NARISADA Masayuki

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
30. ALAN CHAIT

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
31. GOLDSTEIN Jo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
32. 長野洋幸

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

NAGANO Yutaka 長野 豊

永野 豊 ナカ゛ノ ユタカ

Research Projects

Research Products

Co-Researchers

Establishment of biomarkers that reflect periodontal conditionPrincipal Investigator

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Principal Investigator

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Elucidation of the relevance between oral health and common systemic diseases -an approach for early detection and treatment of periodontitis-Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the role of fractalkine in chronic inflammatory diseases -An approach for its clinical applicationPrincipal Investigator

Principal Investigator

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Research Institution

Principal Investigator

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NAGANO Yutaka 長野豊

永野豊ナカ゛ノユタカ