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HAISHIMA Yuji  〓島 由二

… Alternative Names

はい島 由二  ハイシマ ユウジ

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Researcher Number 80228379
Other IDs
  • ORCIDhttps://orcid.org/0009-0000-1781-5554
Affiliation (based on the past Project Information) *help 2005 – 2006: 国立医薬品食品衛生研究所, 療品部, 室長
1999 – 2002: 国立医薬品食品衛生研究所, 療品部, 室長
1999: 日立医療品食品衛生研究所, 療品部, 室長
1997: 国立医薬品食品衛生研究所, 療品部, 室長
1997: National Institute of Health Sciences, Bacteriology, 衛生微生物部, 室長 … More
1996: 国立衛生試験所, 衛生微生物部, 主任研究員
1994 – 1996: 国立衛生試験所, 衛生微生物部, 研究員
1995: National Institute of Health Sciences Microbiology, Researcher, 衛生微生物部, 研究員 Less
Review Section/Research Field
Principal Investigator
Bacteriology (including Mycology) / Morphological basic dentistry
Except Principal Investigator
Morphological basic dentistry / Bacteriology (including Mycology) / Periodontal dentistry / Periodontal dentistry
Keywords
Principal Investigator
エンドトキシン / リピドA / リポ多糖 / アンタゴニスト / Porphyromonas gingivalis
Except Principal Investigator
Porphyromonas gingivalis / rCTB / periodontal disease / fimbria / mucosal vaccination … More / 粘膜免疫 / IgA / 線毛 / Porphyromanas gingivalis / 粘膜ワクチン / 歯周病 / 歯周病ワクチン / C3H / P.gingivalis / synthetic lipid A / antagonist / lipid A / endotoxin / サクシニル化 / 化学合成リピドA / アンタゴニスト / リピドA / エンドトキシン / biological properties / lipopolysaccharide / 化学合成 / 生物活性 / 合成リピドA / 内毒素 / 歯周病モデル動物 / 歯槽骨吸収 / 経鼻投与 / (8)血清型 / (7)莢膜 / rCTBコンジュゲート / (6)LPS / (5)rCTB / (4)LPS / (3)Porphyromonas gingivalis / (2)粘膜免疫 / (1)歯周病ワクチン / 無毒化LPS / リコンビナントコレラトキシンB / 分泌型IgA / 歯周病予防 / LPS / リコンビナントコレラトキシン / プロテアーゼ阻害剤 / ワクチン / 経鼻免疫 / TNF-alpha / HeJ mice / HeJマウス / succinylation Less
  • Research Projects

    (9 results)
  • Co-Researchers

    (9 People)
  •  A drug development study for a periodontal disease : Biological properties of synthetic lipid A of Porphyromonas gingivalis lipopolysaccharide

    • Principal Investigator
      KUMADA Hidefumi
    • Project Period (FY)
      2005 – 2006
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Kanagawa Dental College
  •  Intranasal immunization of mice with P. gingivalis fimbriae and recombinant cholera toxin B subunit induces strong mucosal and systemic immune responses

    • Principal Investigator
      KUMADA Hidefumi
    • Project Period (FY)
      2001 – 2002
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Prevention and treatment of periodntal disease ; the developments of mucosal vaccination and protease inhibitor

    • Principal Investigator
      UMEMOTO Toshio
    • Project Period (FY)
      1999 – 2001
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      Kanagawa Dental College
  •  Prevention and treatment of periodontal disease ; the application to basic research and drug development on mucosal vaccination

    • Principal Investigator
      KUMADA Hidefimi
    • Project Period (FY)
      1999 – 2000
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Periodontal dentistry
    • Research Institution
      Kanagawa Dental College
  •  細菌内毒素アンタゴニスト構造体の分子モデリング(II)-アンタゴニスト活性に対するリン酸基の影響-Principal Investigator

    • Principal Investigator
      はい島 由二
    • Project Period (FY)
      1996
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      国立衛生試験所
  •  Elucidation of the chemical factor controlling the antagonistic structure of the lipid A, and mechanism of its suppressive activity

    • Principal Investigator
      TANAMOTO Ken-ichi
    • Project Period (FY)
      1996 – 1997
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      NATIONA INSTITUTE OF HEALTH SCIENCES
  •  細菌内毒素アンタゴニスト構造体の分子モデリング-光学異性リピドAアナログの化学合成-Principal Investigator

    • Principal Investigator
      配島 由二
    • Project Period (FY)
      1995
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      国立衛生試験所
  •  Porphyromonas gingivalisのリピドAアナログの化学合成Principal Investigator

    • Principal Investigator
      配島 由二
    • Project Period (FY)
      1994
    • Research Category
      Grant-in-Aid for Encouragement of Young Scientists (A)
    • Research Field
      Morphological basic dentistry
    • Research Institution
      国立衛生試験所
  •  Elucidation of the chemical structure possessing antagonistic activity of endotoxin using chemical synthesis

    • Principal Investigator
      TANAMOTO Kenich
    • Project Period (FY)
      1994 – 1995
    • Research Category
      Grant-in-Aid for General Scientific Research (C)
    • Research Field
      Bacteriology (including Mycology)
    • Research Institution
      National Institute of Health Sciences
  • 1.  KUMADA Hidefumi (60120995)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 2.  HAMADA Nobushiro (20247315)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 0 results
  • 3.  WATANABE Kiyoko (70148021)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 4.  OZONO Satou (40084785)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  TAKAHASHI Yusuke (20267511)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 6.  TANAMOTO Kenich (60107430)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 7.  ISHIKAWA Eriko (10104340)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 8.  UMEMOTO Toshio (20067036)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  AMANO Shigeru (90167958)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results

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