HORIE Ryouichi 堀江良一

… Alternative Names

堀江良一ホリエリヨウイチ

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Researcher Number	80229228
External Links
Affiliation (Current)	2025: 神奈川工科大学, 健康医療科学部, 研究員
Affiliation (based on the past Project Information) *help	2023: 神奈川工科大学, 健康医療科学部, 研究員 2016 – 2022: 北里大学, 医療衛生学部, 教授 2007 – 2015: Kitasato University, Facutly of Medicine, Associate Professor 2002 – 2006: 北里大学, 医学部, 助教授 2000 – 2003: 北里大学, 医学部, 講師 1997: 東京大学, 医学部, 助手 1997: 東京大学, 医学部附属病院, 助手
Review Section/Research Field	Principal Investigator Human pathology / Basic Section 49020:Human pathology-related / Human pathology / Hematology Except Principal Investigator Human pathology / Hematology / Hematology / Basic Section 49020:Human pathology-related / Human pathology
Keywords	Principal Investigator JunB / CD30 / NF-κB / Hodgkinリンパ腫 / NPM-ALK / 未分化大細胞型リンパ腫 / P80 / ホジキンリンパ腫 / ゲノム異常 / PD-L1 … More / ATL / HTLV-1 / Hodgkin lymphoma / CD30 promoter / NF-kB / 未分化大細胞性リンパ腫 / Ets-1 / NF-κB阻害薬 / 腫瘍化 / chromosomal instability / flower cell / Tax / PI3K / ROS / genomic instability / 活性酸素種 / 幹細胞 / 低酸素誘導因子 / 細胞分化 / HIF-1 / 活性酸素 / 分化 / anaplastic large cell lymphoma / ALCL / Nf-kB / Hogkinリンパ腫 / Hodgkin and Reed-Sternberg cells / Hodgkin's lymphoma / signalosome / IKK / NIK / TRAF / IL-13 / Hodgkin、Reed-Sternberg細胞 / Hodgkin、Reed-sternberg細胞 / multimer formation / functional domain / translin / DNA binding protein / chromosomal translocation / hematologic neoplasm / 遺伝子組み換え / 多量体形成 / 機能ドメイン / トランスリン / DNA結合蛋白 / 染色体転座 / 造血器腫瘍 / Hodgkin リンパ腫 / シグナル伝達 / ALK / HSP90 / CD40 / LMP-1 / EBウイルス / Hodkinリンパ腫 / NPM-Alk / ポジキンリンパ腫 … More Except Principal Investigator CD30 / myosin / ATL / HTLV-1 / NF-kB / クローニング / 血小板 / ミオシン軽鎖 / 血液細胞 / ミオシン / シグナル伝達 / 癌 / DNA methylation / NPM-ALK / ALCL / Hodgkin's Lymphoma / アイソフォーム / ミオシン重鎖 / platelet / cloning / cDNA / myosin I / EBウイルス / リンパ芽球様細胞株 (LCL) / ホジキンリンパ腫 / isoform / 単球 / 非古典的ミオシン / LMP-1 / リンパ芽球様細胞株(LCL) / Epstein-Barr(EB)ウイルス / リンパ増殖性疾患 / リンパ芽球様細胞株 / RNA Sequence / CGH 法 / CD30L / Epstein-Barr ウイルス / CD30 ligand / RNAシークエンス / アレイCGH法 / LCL / ゲノム異常 / Epstein-Barr (EB) ウイルス / リンパ芽球様細胞株（LCL） / Epstein―Barr virus (EBV) / Virus / T-lymphocytes / Signal transduction / Cancer / ウイルス / ウィルス / Tリンパ球 / molecular pathophysiology / diagnosis / lymphoma / signal transduction / cancer / Hodgkin lymphoma / expression profile / DNA microarray / TRAF protein / 分子病態 / 診断 / リンパ腫 / mutant / MYH-9 / proplatelet / may-Hegglin anomaly / myosin sunerfamily / バキュロウイルス / rho-kinase / rho / GFP / 軽鎖 / 遺伝子異常 / 遺伝子変異 / TRAF蛋白質 / DNAアレイ / 受容体シグナル / Anaplastic Large Cell Lymphoma / ホジキン病 / unconventional myosin / lymphocyte / myosin light chain / myosin heavy chain / リン酸化 / library / sequence / cord blood / モノクローナル抗体 / 網血小板 / mpl / ライブラリー / シークエンス / 臍帯血 / Hodgkinリンパ腫 / CD0 / EB ウイルス / Epstein-Barr virus (EBV) / 分子標的療法 / 細胞分化 / ニッチ / 癌幹細胞 / 巨核球 / Golgi complex / ミオシン・スーパーファミリー / Jurkat細胞 / 多発性骨髄腫 / 白血病細胞株 / myosin X / myosin VI / myosinVI / MYH9 異常症 Less

Roles of NF-kB activation in tumorigenesis of HTLV-1-infected cells by CD30Principal Investigator
- Principal Investigator
  
  堀江良一
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kanagawa Institute of Technology
Genomic instability and tumorigenesis by CD30 in HTLV-1-infected cellsPrincipal Investigator
- Principal Investigator
  
  Horie Ryouichi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kitasato University
Genomic abnormalities by CD30 and their roles in the tumorigenic process of Epstein-Barr virus-infected cells
- Principal Investigator
  
  WATANABE Mariko
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49020:Human pathology-related
- Research Institution
  Kitasato University
Regulation of Hodgkin lymphoma cell differentiation by reactive oxygen speciesPrincipal Investigator
- Principal Investigator
  
  Horie Ryouichi
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Analyses of molecular pathogenesis of Hodgkin lymphoma by transformation of B cells and humanized mice model
- Principal Investigator
  
  WATANABE Mariko
- Project Period (FY)
  2014 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Signal integration by CD30 through HSP90 in classical Hodgkin lymphomaPrincipal Investigator
- Principal Investigator
  
  Horie Ryouichi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Analyses of molecular bases of cancer stem cells and their differentiation in Hodgkin lymphoma
- Principal Investigator
  
  WATANABE MARIKO
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Analyses of molecular bases by LMP-1 and CD30, which mediate transformation of lymphocytes to Hodgkin lymphoma cellsPrincipal Investigator
- Principal Investigator
  
  HORIE RYOUICHI
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Molecular mechanisms of Hodgkin and anaplastic large cell lymhoma triggered by CD30 induction and P80Principal Investigator
- Principal Investigator
  
  HORIE Ryouichi
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Pathological analyses of myosin superfamily disorders
- Principal Investigator
  
  HIGASHIHARA Masaaki
- Project Period (FY)
  2006 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kitasato University
Abnormalities in TCR signal transduction in T cell non-Hodgkin's lymphoma as a basis for a new classification system.
- Principal Investigator
  
  WATANABE Toshiki
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  The University of Tokyo
Analysis of molecular basis for occurance of Hodgkin lympnoma and anaplastic large cell lymphomaPrincipal Investigator
- Principal Investigator
  
  HORIE Ryouichi
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  Kitasato University
Studies on abnormalities of membrane receptor signaling in malignant lymphoma cells as a basis of diagnosis and treatment
- Principal Investigator
  
  WATANABE Toshiki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  The University of Tokyo
Analyses of phenotypic changes of Hodgkin and Reed-Stemberg cells to anaplastic large cell lymphoma cells by p80.Principal Investigator
- Principal Investigator
  
  HORIE Ryouichi
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KITASATO UNIVERSITY
Functional analysis of myosin superfamily in blood cells
- Principal Investigator
  
  HIGASHIHARA Masaaki
- Project Period (FY)
  2003 – 2004
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kitasato University
Molecular analysis of aberrant signal transduction of membrane receptors as a basis for diagnosis and treatment of malignant lymphomas
- Principal Investigator
  
  WATANABE Toshiki
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Human pathology
- Research Institution
  The University of Tokyo
Analyses of molecular bases of Hodgkin lymphoma by CD30-NF-kB pathway.Principal Investigator
- Principal Investigator
  
  HORIE Ryouichi
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Human pathology
- Research Institution
  KITASATO UNIVERSITY
Analysis of expression and function of myosins in hematological cells
- Principal Investigator
  
  HIGASHIHARA Masaaki
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  Kitasato University
Genetic and functional analysis of myosin I of blood cells
- Principal Investigator
  
  HIGASHIHARA Masaaki
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  KITASATO UNIVERSITY
Clarification of the mechanism involved in chromosomal translocations founded in hematologic neoplasms.Principal Investigator
- Principal Investigator
  
  AOKI Katsunori, 堀江良一
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Hematology
- Research Institution
  The University of Tokyo

[Book] 特集　ホジキンリンパ腫2016
- Author(s)
  堀江良一
- Total Pages
  148
- Publisher
  医薬ジャーナル
- Data Source
  KAKENHI-PROJECT-26460440
[Book] 特集　ホジキンリンパ腫2016
- Author(s)
  堀江良一
- Total Pages
  148
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-26460439
[Book] 実験医学増刊Vol.302012
- Author(s)
  堀江良一, 他
- Total Pages
  224
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23590433
[Book] シグナル伝達　研究最前線　２０１２2012
- Author(s)
  堀江良一　他
- Total Pages
  222
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23590433
[Book] 実験医学増刊Vol.302012
- Author(s)
  堀江良一, 他
- Total Pages
  224
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-23590432
[Book] 病理と臨床Vol.29 2011年臨時増刊号2011
- Author(s)
  堀江良一, 他
- Total Pages
  545
- Publisher
  文光社
- Data Source
  KAKENHI-PROJECT-23590432
[Book] 悪性リンパ腫の基礎と臨床2011
- Author(s)
  堀江良一, 他
- Total Pages
  538
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590374
[Book] 病理と臨床Vol.29 2011年臨時増刊号2011
- Author(s)
  堀江良一, 他
- Total Pages
  545
- Publisher
  文光社
- Data Source
  KAKENHI-PROJECT-23590433
[Book] みんなに役立つ悪性リンパ腫の基礎と臨床(リンパ腫微小環境)(押味和夫編)
- Author(s)
  堀江良一
- Publisher
  医薬ジャーナル社
- Data Source
  KAKENHI-PROJECT-20590374
[Book] 病理診断に役立っ分子生物学(臨時増刊号29)(金井弥栄、石川俊平、池田栄一編)(病理と臨床)
- Author(s)
  堀江良一
- Publisher
  文光堂
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] CD30 nduces Reed‐Sternberg cell‐like morphology and chromosomal instability in classic Hodgkin lymphoma cell lines2023
- Author(s)
  Watanabe Mariko、Hatsuse Hiromi、Nagao Kazuaki、Nakashima Makoto、Uchimaru Kaoru、Otsu Makoto、Miyazaki Koji、Horie Ryouichi
- Journal Title
  
  Cancer Science
  
  Volume: 114 Issue: 8 Pages: 3433-3445
- DOI
  10.1111/cas.15874
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06429, KAKENHI-PROJECT-22K15420
[Journal Article] CD30 stimulation induces multinucleation and chromosomal instability in HTLV-1-infected cell lines2023
- Author(s)
  Watanabe Mariko、Hatsuse Hiromi、Nagao Kazuaki、Tanaka Yuetsu、Watanabe Toshiki、Horie Ryouichi
- Journal Title
  
  International Journal of Hematology
  
  Volume: 118 Issue: 1 Pages: 75-87
- DOI
  10.1007/s12185-023-03583-1
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K06429
[Journal Article] Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase‐1 through HIF‐1α2021
- Author(s)
  Nakashima Makoto、Watanabe Mariko、Nakano Kazumi、Uchimaru Kaoru、Horie Ryouichi
- Journal Title
  
  Cancer Science
  
  Volume: 112 Issue: 6 Pages: 2542-2555
- DOI
  10.1111/cas.14890
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16580, KAKENHI-PROJECT-19K07442, KAKENHI-PROJECT-20K07379
[Journal Article] Impact of Anti-GPIIb/IIIa antibody-producing B cells as a predictor of the response to lusutrombopag in thrombocytopenic patients with liver disease.2020
- Author(s)
  Wada N, Uojima H, Satoh T, Okina S, Iwasaki S, Shao X, Takiguchi H, Arase Y, Itokawa N, Atsukawa M, Miyazaki K, Hidaka H, Kako M, Kagawa T, Iwakiri K, Horie R, Suzuki T, Koizumi W.
- Journal Title
  
  Dig Dis.
  
  Volume: Aug 6 Issue: 3 Pages: 1-9
- DOI
  10.1159/000510692
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07379
[Journal Article] Jietacins, azoxy natural products, as novel NF-kB inhibitors: discovery, synthesis, biological activity, and mode of action2019
- Author(s)
  Mariko Watanabe, Akihiro Sugawara, Yoshihiko Noguchi, Tomoyasu Hirose, Satoshi Omura, Toshiaki Sunazuka, Ryouichi Horie
- Journal Title
  
  Eur. J. Med. Chem.
  
  Volume: 178 Pages: 636-647
- DOI
  10.1016/j.ejmech.2019.05.079
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06586, KAKENHI-PROJECT-19K07442, KAKENHI-PROJECT-19K16318, KAKENHI-PROJECT-17K08728
[Journal Article] CD30 characterizes polylobated lymphocytes and disease progression in HTLV-1-infected individuals.2018
- Author(s)
  Nakashima M, Yamochi T, Watanabe M, Uchimaru K, Utsunomiya A, Higashihara M, Watanabe T, Horie R.
- Journal Title
  
  Clin Cancer Res.
  
  Volume: 24 Issue: 21 Pages: 5445-5457
- DOI
  10.1158/1078-0432.ccr-18-0268
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08728, KAKENHI-PROJECT-16H05248, KAKENHI-PROJECT-16H06277
[Journal Article] Role of exosomes as a proinflammatory mediator in the development of EBV-associated lymphoma.2018
- Author(s)
  Higuchi H, Yamakawa N, Imadome KI, Yahata T, Kotaki R, Ogata J, Kakizaki M, Fujita K, Lu J, Yokoyama K, Okuyama K, Sato A, Takamatsu M, Kurosaki N, Alba SM, Azhim A, Horie R, Watanabe T, Kitamura T, Ando K, Kashiwagi T, Matsui T, Okamoto A, Handa H, Kuroda M, Nakamura N, Kotani A.
- Journal Title
  
  Blood
  
  Volume: 131 Issue: 23 Pages: 2552-2567
- DOI
  10.1182/blood-2017-07-794529
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K08728, KAKENHI-PROJECT-18K15402, KAKENHI-PROJECT-17H04067, KAKENHI-PROJECT-17H04212
[Journal Article] Relationship between response to lusutrombopag and splenic volume.2018
- Author(s)
  Uojima H, Arase Y, Itokawa N, Atsukawa M, Satoh T, Miyazaki K, Hidaka H, Sung JH, Kako M, Tsuruya K, Kagawa T, Iwakiri K, Horie R, Koizumi W.
- Journal Title
  
  World J Gastroenterol.
  
  Volume: 24 Issue: 46 Pages: 5271-5279
- DOI
  10.3748/wjg.v24.i46.5271
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K08728
[Journal Article] Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling.2018
- Author(s)
  Nakashima M, Watanabe M, Uchimaru K, Horie R.
- Journal Title
  
  Biol Cell.
  
  Volume: 110 Issue: 5 Pages: 1-16
- DOI
  10.1111/boc.201800002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460439, KAKENHI-PROJECT-16H06277
[Journal Article] Trogocytosis of ligand-receptor complex and its intracellular transport in CD30 signalling.2018
- Author(s)
  Nakashima M, Watanabe M, Uchimaru K, Horie R.
- Journal Title
  
  Biol Cell.
  
  Volume: 110 Pages: 1-16
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K08728
[Journal Article] CD30 induces heat shock protein 90 and signal integration in classic Hodgkin lymphoma cells2017
- Author(s)
  Watanabe M, Nakano K, Kadin ME, Higashihara M, Watanabe T, Horie R
- Journal Title
  
  Am J Pathol
  
  Volume: 187 Issue: 1 Pages: 163-175
- DOI
  10.1016/j.ajpath.2016.09.007
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460440, KAKENHI-PROJECT-26460439
[Journal Article] Sucsessful treatment with ibrutinib of intractable thrombocytopenia associated with recurrent chronic lymphocytic leukemia2017
- Author(s)
  Ishida T, Yokoyama M, Danbara M, Michisita Y, Horie R, Higashihara M, Miyazaki K
- Journal Title
  
  The Kitasato Medical Journal
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460440
[Journal Article] Brefeldin A exerts differential effects on anaplastic lymphoma kinase positive anaplastic large cell lymphoma and classical Hodgkin lymphoma cell lines2015
- Author(s)
  Toda T, Watanabe M, Kawato J, Kadin ME, Higashihara M, Kunisada T, Umezawa K, and Horie R
- Journal Title
  
  Br J Haematol
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460439
[Journal Article] Immature platelet fraction measurement is influenced by platelet size and is a useful parameter for discrimination of macrothrombocytopenia2015
- Author(s)
  Miyazaki K, Koike Y, Kunishima S, Ishii R, Danbara M, Horie R, Yatomi Y, Higashihara M
- Journal Title
  
  Hematology
  
  Volume: 20 Issue: 10 Pages: 587-592
- DOI
  10.1179/1607845415y.0000000021
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26460439, KAKENHI-PROJECT-26460440
[Journal Article] Brefeldin A exerts differential effects on anaplastic lymphoma kinase positive anaplastic large cell lymphoma and Hodgkin lymphoma cell lines.2015
- Author(s)
  T. Toda, M. Watanabe, J. Kawato, M. Higashihara, T. Kunisada, K. Umezawa and R. Horie
- Journal Title
  
  British J. Haematology
  
  Volume: 170 Issue: 6 Pages: 837-846
- DOI
  10.1111/bjh.13508
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26350975, KAKENHI-PROJECT-26460439, KAKENHI-PROJECT-26460440
[Journal Article] Brefeldin A exerts differential effects on anaplastic lymphoma kinase positive anaplastic large cell lymphoma and classical Hodgkin lymphoma cell lines2015
- Author(s)
  Toda T, Watanabe M, Kawato J, Kadin ME, Higashihara M, Kunisada T, Umezawa K, and Horie R
- Journal Title
  
  Br J Haematol
  
  Volume: in press
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460440
[Journal Article] Activation of Akt involves resistance to NF-κB inhibition and abrogation of both triggers synergistic apoptosis in lung adenocarcinoma cells2014
- Author(s)
  Togano T, Watanabe M, Itoh K, Umezawa K, Masuda N, Higashihara M, Horie R
- Journal Title
  
  Lung Cancer
  
  Volume: 83 Issue: 2 Pages: 139-145
- DOI
  10.1016/j.lungcan.2013.10.018
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] Combined inhibition of NF-κB and Bcl-2 triggers synergistic reduction of viability and induces apoptosis in melanoma cells2014
- Author(s)
  Watanabe M, Umezawa K, Higashihara M, Horie R
- Journal Title
  
  Oncol Res
  
  Volume: 印刷中
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Combined inhibition of NF-κB and Bcl-2 triggers synergistic reduction of viability and induces apoptosis in melanoma cells2014
- Author(s)
  Watanabe M, Umezawa K, Higashihara M, Horie R.
- Journal Title
  
  Oncol Res
  
  Volume: 未定
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] ホジキンリンパ腫と未分化大細胞型リンパ腫におけるCD30過剰発現機構2014
- Author(s)
  堀江良一
- Journal Title
  
  血液内科
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Combined inhibition of NF-κB and Bcl-2 triggers synergistic reduction of viability and induces apoptosis in melanoma cells2014
- Author(s)
  Watanabe M, Umezawa K, Higashihara M, Horie R
- Journal Title
  
  Oncol Res.
  
  Volume: 21(4) Issue: 4 Pages: 173-80
- DOI
  10.3727/096504014x13887748696707
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] ジキンリンパ腫と未分化大細胞型リンパ腫におけるCD30過剰発現機構2014
- Author(s)
  堀江良一
- Journal Title
  
  血液内科
  
  Volume: (印刷中)
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Current Molecular Targets of Lymphomas2013
- Author(s)
  Horie R.
- Journal Title
  
  Forum Immun Dis Ther
  
  Volume: 4(1) Pages: 11-23
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24369220
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Molecularly-targeted strategy and NF-κB in lymphoid malignancies2013
- Author(s)
  Horie R
- Journal Title
  
  J Clin Exp Hematop
  
  Volume: 53 Pages: 185-95
- NAID
  130003383993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Current Molecular Targets of Lymphomas2013
- Author(s)
  Horie R
- Journal Title
  
  Forum Immun Dis Ther
  
  Volume: ４ Pages: 11-23
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Molecularly-targeted strategy and NF-κB in lymphoid malignancies2013
- Author(s)
  Horie R
- Journal Title
  
  J Clin Exp Hematop
  
  Volume: 53 Pages: 185-95
- NAID
  130003383993
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Molecularly-targeted strategy and NF-κB in lymphoid malignancies2013
- Author(s)
  Horie R
- Journal Title
  
  J Clin ExpHematop
  
  Volume: 53(3) Pages: 185-95
- NAID
  130003383993
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24369220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Hodgkinリンパ腫の発症・維持における炎症の役割2013
- Author(s)
  堀江良一
- Journal Title
  
  血液内科
  
  Volume: 67 Pages: 460-466
- URL
  http://www.kahyo.com/item/KS201310-674
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Hodgkinリンパ腫の発症・維持における炎症の役割2013
- Author(s)
  堀江良一
- Journal Title
  
  血液内科
  
  Volume: 67 Pages: 460-466
- URL
  http://www.kahyo.com/item/KS201310-674
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Molecularly-targeted strategy and NF-κB in lymphoid malignancies2013
- Author(s)
  Horie R.
- Journal Title
  
  J Clin ExpHematop
  
  Volume: 53(3) Pages: 185-95
- NAID
  130003383993
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/24369220
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Current Molecular Targets of Lymphomas2013
- Author(s)
  Horie R
- Journal Title
  
  Forum Immun Dis Ther
  
  Volume: 4(1) Issue: 1 Pages: 11-23
- DOI
  10.1615/forumimmundisther.2013008322
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Incidence and clinical significance of abberrant T-cell marker expression on diffuse large B-cell lymphoma cells.2013
- Author(s)
  Suzuki Y, Yoshida T, Wang G, Aoki T, Katayama T, Miyamoto S, Miyazaki K, Iwabuchi K, Danbara M, Nakayama M, Horie R, Nakamine H, Sato Y, Nakamura N, Niitsu N.
- Journal Title
  
  Acta Hematologica
  
  Volume: 130 Issue: 4 Pages: 230-237
- DOI
  10.1159/000348550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590414, KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433, KAKENHI-PROJECT-24590703
[Journal Article] Surface CD3 expression proceeds through both myosin regulatory light chain 9 (MYL9)-dependent and MYL9-independent pathways in Jurkat cells2012
- Author(s)
  Aoki T, Miyazaki K, Katayama T, Watanabe M, Horie R, Danbara M, Higashihara M
- Journal Title
  
  J Smooth Muscle Res.
  
  Volume: 48(5-6) Pages: 137-47
- NAID
  10031151480
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/23538510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Surface CD3 expression proceeds through both myosin regulatory light chain 9 (MYL9)-dependent and MYL9-independent pathways in Jurkat cells2012
- Author(s)
  Aoki T, Miyazaki K, Katayama T, Watanabe M, Horie R, Danbara M, Higashihara M
- Journal Title
  
  J Smooth Muscle Res.
  
  Volume: 48(5-6) Pages: 137-47
- NAID
  10031151480
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/23538510
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Involvement of DNA binding domain in the cellular stability and importin affinity of NF-κB component RelB2012
- Author(s)
  Takeiri, M., Horie, K., Takahashi, D., Watanabe, M., Horie, R., Simizu, S. & Umezawa, K
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 10 Issue: 15 Pages: 3053-3059
- DOI
  10.1039/c2ob07104e
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-20113008, KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] Targeted Repression of Overexpressed CD30 Downregulates NF-κB and ERK1/2 Pathway in Hodgkin Lymphoma Cell Lines2012
- Author(s)
  Watanabe M, Nakano K, Togano T, Nakashima M, Higashihara M, Kadin M.E., Watanabe, T, Horie R
- Journal Title
  
  Oncol Res.
  
  Volume: 19(10-11) Pages: 463-9
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22715589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Synergistic effect of 5-azacytidine and NF-κB inhibitor DHMEQ on apoptosis induction in myeloid leukemia cells2012
- Author(s)
  Togano T, Nakashima M, Watanabe M,Umezawa K, Watanabe T, Higashihara M, Horie R
- Journal Title
  
  Oncol Res.
  
  Volume: 20(12) Issue: 12 Pages: 571-7
- DOI
  10.3727/096504013x13775486749371
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] Ets-1 activates overexpression of JunB and CD30 in Hodgkin's lymphoma and anaplastic large-cell lymphoma2012
- Author(s)
  Watanabe M, Itoh K, Togano T, Kadin ME, Watanabe T, Higashihara M, Horie R
- Journal Title
  
  Am J Pathol
  
  Volume: 180(2) Issue: 2 Pages: 831-8
- DOI
  10.1016/j.ajpath.2011.10.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] Surface CD3 expression proceeds through both myosin regulatory light chain 9 (MYL9)-dependent and MYL9-independent pathways in Jurkat cells.2012
- Author(s)
  Aoki T, Miyazaki K, Katayama T, Watanabe M, Horie R, Danbara M, Higashihara M.
- Journal Title
  
  J Smooth Muscle Res.
  
  Volume: 48(5-6) Pages: 137-47
- NAID
  10031151480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590433
[Journal Article] Targeted Repression of Overexpressed CD30 Downregulates NF-κB and ERK1/2 Pathway in Hodgkin Lymphoma Cell Lines2012
- Author(s)
  Watanabe M, Nakano K, Togano T, Nakashima M, Higashihara M, Kadin M.E., Watanabe, T, Horie R
- Journal Title
  
  Oncol Res.
  
  Volume: 19(10-11) Pages: 463-9
- URL
  http://www.ncbi.nlm.nih.gov/pubmed/22715589
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Surface CD3 expression proceeds through both myosin regulatory light chain 9 (MYL9)-dependent and MYL9-independent pathways in Jurkat cells.2012
- Author(s)
  Aoki T, Miyazaki K, Katayama T, Watanabe M, Horie R, Danbara M, Higashihara M.
- Journal Title
  
  J Smooth Muscle Res.
  
  Volume: 48(5-6) Pages: 137-47
- NAID
  10031151480
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432
[Journal Article] Association of CD20 levels with clinicopathological parameters and its prognostic significance for patients with DLBCL2012
- Author(s)
  Suzuki Y, Yoshida T, Wang G, Togano T, Miyamoto S, Miyazaki K, Iwabuchi K, Nakayama M, Horie R, Niitsu N, Sato Y, Nakamura N
- Journal Title
  
  Ann Hematol
  
  Volume: 91(7) Issue: 7 Pages: 997-1005
- DOI
  10.1007/s00277-012-1407-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590414, KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] A patient with acute lymphoblastic leukaemia presenting with an extremely high level (21.0%) of HbA1c2011
- Author(s)
  Suzuki Y, Shichishima T, Yamashiro Y, Kimura H, Ishii R, Miyazaki K, Horie R, Moriya T, Hattori Y
- Journal Title
  
  Ann Clin Biochem
  
  Volume: 48(5) Issue: 5 Pages: 474-477
- DOI
  10.1258/acb.2011.010121
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22591044, KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] The side population, as a precursor of Hodgkin and Reed-Sternberg cells and a target for nuclear factor-κB inhibitors in Hodgkin's lymphoma2011
- Author(s)
  Nakashima M, Ishii Y, Watanabe M, Togano T, Umezawa K, Higashihara M, Watanabe T, Horie R
- Journal Title
  
  Cancer Sci
  
  Volume: 101(11) Issue: 11 Pages: 2490-6
- DOI
  10.1111/j.1349-7006.2010.01693.x
- NAID
  10027834044
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] Re-appearance of hepatitis B virus following therapy with rituximab for lymphoma is not rare in Japanese patients with past hepatitis B virus infection2011
- Author(s)
  Watanabe M, Shibuya A, Tsunoda Y, Danbara M, Ishii R, Ohsaka M, Takada J, Tanaka Y, Okuwaki Y, Minamino T, HidakaH, Nakazawa T, Horie R, Higashihara M, Koizumi W
- Journal Title
  
  Liver Int.
  
  Volume: 31(3) Issue: 3 Pages: 340-7
- DOI
  10.1111/j.1478-3231.2010.02417.x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590432, KAKENHI-PROJECT-23590433
[Journal Article] Inhibition of active HIV-1 replication by NF-kappaB inhibitor DHMEQ.2010
- Author(s)
  Miyake A, Ishida T, Yamagishi M, Hara T, Umezawa K, Watanabe T, Horie R.
- Journal Title
  
  Microbes Infect. 12
  
  Pages: 400-408
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Constitutive activity of nuclear transcription factor kappaB is observed in follicular lymphoma.2010
- Author(s)
  Suzuki Y, Yoshida T, Horie R, Tsuruta T, Togano T, Ohsaka M, Miyazaki K, Danbara M, Ohtani S, Okayasu I, Higashihara M.
- Journal Title
  
  J Clin Exp Hematop. 50
  
  Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] CD3- and CD4-positive plasmablastic lymphoma: a literature review of JapanesePlasmablastic, lymphoma cases.2010
- Author(s)
  Suzuki Y, Yoshida T, Nakamura N, Kamata H, Kotani S, Ohsaka M, Kajita S, Miyazaki K, Ohtani S, Nakayama M, Horie R, Hayakawa K, Niitsu N, Higashihara M.
- Journal Title
  
  Intern Med. 49
  
  Pages: 1801-1805
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] CD3- and CD4-positive plasmablastic lymphoma : a literature review of Japanese Plasmablastic lymphoma cases.2010
- Author(s)
  Suzuki Y(10名)Horie R(3名)
- Journal Title
  
  Intern Med.
  
  Volume: 49 Pages: 1801-1805
- NAID
  130000299647
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Constitutive activity of nuclear transcription factor kappaB is observed in follicular lymphoma.2010
- Author(s)
  Suzuki Y(1名)Horie R(8名)
- Journal Title
  
  J Clin Exp Hematop.
  
  Volume: 50 Pages: 45-50
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Inhibition of active HIV-1 replication by NF-kappaB inhibitor DHMEQ.2010
- Author(s)
  Miyake A, (3名), Horie R
- Journal Title
  
  Microbes and Infection (in press, [Epub ahead of print])
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] A case of giardiasis expressing severe systemic symptoms and marked, hypereosinophilia.2010
- Author(s)
  Suzuki Y, Nakamura T, Tokoro M, Togano T, Ohsaka M, Kohri M, Hirata Y, Miyazaki K, Danbara M, Horie R, Miura I, Sunakawa K, Higashihara M.
- Journal Title
  
  Parasitol Int. 59
  
  Pages: 487-489
- NAID
  10029825838
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] The side population, as a precursor of Hodgkin and Reed-Sternberg cells and a target for nuclear factor-kB inhibitors in Hodgkin's lymphoma.2010
- Author(s)
  Nakashima M(6名) Horie R
- Journal Title
  
  Cancer Sci.
  
  Volume: 101 Pages: 2490-2496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] The side population, as a precursor of Hodgkin and Reed-Sternberg cells and a target for nuclear factor-kappaB inhibitors in Hodgkin's lymphoma.2010
- Author(s)
  Nakashima M, Ishii Y, Watanabe M, Togano T, Umezawa K, Higashihara M, Watanabe T, Horie R.
- Journal Title
  
  Cancer Sci. 101
  
  Pages: 2490-2496
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Induction of oncogene addiction shift to NF-kB by camptothecin in solid tumor cells.2009
- Author(s)
  Togano T, (7名), Horie R
- Journal Title
  
  Biochem Biophys Res Commun 390
  
  Pages: 60-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] CD20-positive T-cell large granular lymphocyte leukemia: case report and review of the literature.2009
- Author(s)
  Miyazaki K, Ohsaka M, Suzuki Y, Danbara M, Horie R, Higashihara M.
- Journal Title
  
  Intern Med. 48
  
  Pages: 1443-1447
- NAID
  130000122030
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Induction of oncogene addiction shift to NF-kB by camptothecin in solid tumor cells.2009
- Author(s)
  Togano T, Sasaki M, Watanabe M, Makoto Nakashima M, Tsuruo T, Umezawa K, Higashihara M, Toshiki Watanabe T, Horie R.
- Journal Title
  
  Biochem Biophys Res Commun. 390
  
  Pages: 60-64
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Transient inhibition of NF-kappaB by DHMEQ induces cell death of primary effusion lymphoma without HHV-8 reactivation.2009
- Author(s)
  Dabaghmanesh N, Matsubara A, Miyake A, Nakano K, Ishida T, Katano H, Horie R, Umezawa K, Watanabe T.
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 737-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Lymphoproliferative disorders after immunosuppressive therapy for aplastic anemia: a case report and literature review.2009
- Author(s)
  Suzuki Y, Niitsu N, Hayama M, Katayama T, Ishii R, Osaka M, Miyazaki K, Danbara M, Horie R, Yoshida T, Nakamura N, Higashihara M.
- Journal Title
  
  Acta Haematol. 121
  
  Pages: 21-26
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Transient inhibition of NF-kappaB by DHMEQ induces cell death of primary effusion lymphoma without HHV-8 reactivation.2009
- Author(s)
  Dabaghmanesh N, (5名), Horie R, (1名), Watanabe T
- Journal Title
  
  Cancer Sci. 100
  
  Pages: 737-746
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues.2008
- Author(s)
  Yamamoto M, Horie R, (5名).
- Journal Title
  
  J Med Chem. 51
  
  Pages: 5780-5788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Hypomethylation of CD30 CpG islands with aberrant JunB expression drives CD30 induction in Hodgkin lymphoma and anaplastic large cell lymphoma.2008
- Author(s)
  Watanabe M, Ogawa Y, Itoh K, Koiwa T, Kadin ME, Watanabe T, Okayasu I, Higashihara M, Horie R.
- Journal Title
  
  Lab Invest. 88
  
  Pages: 48-57
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues.2008
- Author(s)
  Yamamoto M, Horie R, Takeiri M, Kozawa I, Umezawa K.
- Journal Title
  
  J Med Chem. 51
  
  Pages: 5780-5788
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Identification of the RelA domain responsible for action of a new NF-kappaB inhibitor DHMEQ.2008
- Author(s)
  Watanabe M, (5名), Horie R.
- Journal Title
  
  Biochem Biophys Res Commun. 376
  
  Pages: 310-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Identification of the RelA domain responsible for action of a new NF-kappaB inhibitor DHMEQ.2008
- Author(s)
  Watanabe M, Nakashima M, Togano T, Higashihara M, Watanabe T, Umezawa K, Horie R.
- Journal Title
  
  Biochem Biophys Res Commun. 376
  
  Pages: 310-314
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Induction of apoptosis in Epstein-Barr virus-infected B-lymphocytes by the NF-kB inhibitor DHMEQ2008
- Author(s)
  Miyake A, Dewan MdZ, Ishida T, Watanabe M, Honda M, Sata T, Yamamoto N, Umezawa K, Watanabe T, Horie R.
- Journal Title
  
  Microbes and Infection (in press)
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] Induction of apoptosis in Epstein-Barr virus-infected B-lymphocyteby the NF-κB inhibitor DHMEQ.2008
- Author(s)
  Miyake A, (5名), Horie R.
- Journal Title
  
  Microbes Infect. 10
  
  Pages: 748-756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Induction of apoptosis in Epstein-Barr virus-infected B-lymphocytes by the NF-?B inhibitor DHMEQ.2008
- Author(s)
  Miyake A, Dewan MZ, Ishida T, Watanabe M, Honda M, Sata T, Yamamoto N, Umezawa K, Watanabe T, Horie R.
- Journal Title
  
  Microbes Infect. 10
  
  Pages: 748-56
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590374
[Journal Article] Dehydroxymethylepoxyquinomicin(DHMEQ)therapy reduces tumor formation in mice inoculated with tax-deficient adult T-cell leukemia-derived cell lines2007
- Author(s)
  Ohsugi, T, Kumasaka, T, Okada, S, Ishida, T, Yamaguchi, K, Horie, R, Watanabe, T, Umezawa, K
- Journal Title
  
  Cancer Lett 257(2)
  
  Pages: 206-15
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] TRAF activation of C/EBPβ (NF-IL6) via p38MAPK induces HIV-1 gene expression in monocytes/macrophages2007
- Author(s)
  Horie R, Ishida T, Maruyama-NagaiM, et. al.,
- Journal Title
  
  Micobes and Infection 9
  
  Pages: 721-728
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] IkBalpa independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin-Reed-Sternberg cells.2007
- Author(s)
  Watanabe M, 10名, Horie R
- Journal Title
  
  Lab Invest. 87
  
  Pages: 372-382
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] TRAF activation of C/EBPb (NF-IL6) via p38 MAPK induces HIV-1 gene expre ssion in monocvtes/macrophages2007
- Author(s)
  Horie R, 8名
- Journal Title
  
  Microbes Infect 48
  
  Pages: 721-728
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] TRAF activation of C/EBPβ(NF-lL6)via p38MAPK induces HIV-1 gene expressi on in monocytes/macrophages2007
- Author(s)
  Horie R, Ishida T, Maruyama-Nagai M, et. al.
- Journal Title
  
  Micobes and Infection 9
  
  Pages: 721-728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] Dehydroxymethylepoxyquinomicin(DHMEQ)therapy reduces tumor formation in mice inoculated with tax-deficient adult T-cell leukemia-derived cell lines.2007
- Author(s)
  Ohsugi T, 4名, Horie R, 2名
- Journal Title
  
  Cancer Lett. 257
  
  Pages: 206-215
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] TRAF activation of C/EBPb (NF-IL6) via p38 MAPK induces HIV-1 gene expression in monocytes/macrophages2007
- Author(s)
  Horie, R, Ishida, T, Maruyama-Nagai, M, Ito, K, Watanabe, M, Yoneyama, A, Higashihara, M, Kimura, S, Watanabe, T
- Journal Title
  
  Microbes Infect 48
  
  Pages: 721-8
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] IkBalpa independent induction of NF-kappaB and its inhibition b DHMEQ in Hodgkin-Reed-Sternberg cells2007
- Author(s)
  Watanabe, M, Dewan, MZ, Taira, M, Shoda, M, Honda, M, Sata, T, Higashihara, M, Kadin, ME, Watanabe, T, Yamamoto, N, Umezawa, K, Horie, R
- Journal Title
  
  Lab Invest 87
  
  Pages: 372-82
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] Dehydroxymethylepoxyquinomicin (DHMEQ) therapy reduces tumor formation in mice inoculated with Tax-deficient adult T-cell leukemia-derived cell lines2007
- Author(s)
  Ohsugi T, Kumasaka T, Okada S, Ishida T, Yamaguchi K, Horie R, Watanabe T, Umezawa K.
- Journal Title
  
  Cancer Letters 257
  
  Pages: 206-215
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] IkBalpa independent induction of NF-kappaB and its inhibition by DHMEQ in Hodgkin-Reed-Stemberg cells2007
- Author(s)
  Watanabe M, 10名, Horie R
- Journal Title
  
  Lab Invest 87
  
  Pages: 372-382
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] IκBα independent induction of NF-κB and its inhibition by DHMEQ in Hodgkin-Reed-Sternberg cells.2007
- Author(s)
  Watanabe M, Dewan Md.Z, Taira M, Shoda M, Honda M, Sata T, Higashihara M, Kadin ME, Watanabe T, Yamamoto N, Umezawa K, Horie R
- Journal Title
  
  Laboratory Investigation 87
  
  Pages: 372-382
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] TRAF activation of C/EBPb(NF-IL6)via p38 MAPK induces HIV-1 gene expression in monocytes/macrophages.2007
- Author(s)
  Horie R, 8名
- Journal Title
  
  Microbes Infect. 48
  
  Pages: 721-728
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] TRAF activation of C/EBPb (NF-IL6) via p38 MAPK induces HIV-1 gene expression in monocytes/macrophages2007
- Author(s)
  Horie R, Ishida T, Maruyama-Nagai M, Ito K, Watanabe M, Yoneyama A, Higashihara M, Kimura S, Watanabe T.
- Journal Title
  
  Microbes and Infection 9
  
  Pages: 721-728
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] Dehydroxymethylepoxyquinomicin (DHMEQ) therapy reduces tumor formation inmice inoculated with tax-deficient adult T-cell leukemia-derived cell lines2007
- Author(s)
  Ohsugi T, 4名, Horie R, 2名
- Journal Title
  
  Cancer Lett 257
  
  Pages: 206-215
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] Transactivation of the ICAM-1 gene by CD30 in Hodgkin's lymphoma2006
- Author(s)
  Uchihara JN-4名-Horie R, 他4名
- Journal Title
  
  Int J Cancer 118(5)
  
  Pages: 1098-107
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] DHMEQ,a new NF-kappaB inhibitor,induces apoptosis and enhances fludarabine effects on chronic lymphocytic leukemia cells2006
- Author(s)
  HorieR, 他9名
- Journal Title
  
  Leukemia 20(5)
  
  Pages: 800-6
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] In vitro and in vivo antitumor activity of the NF-kB inhibitor DHMEQ in the human T-cell leukemia virus type I-transformed cell line, HUT-1022006
- Author(s)
  Ohsugi T, Kumasaka T, Ishida A, Ishida T, Horie R, Watanabe T, Umezawa K, Yamaguchi K.
- Journal Title
  
  Leuk Res 30
  
  Pages: 90-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] In vitro and in vivo antitumor activity of the NF-kappaB inhibitor DHMEQ in the human cell leukemia virus type I-infected cell line,HUT-1022006
- Author(s)
  Ohsugi T-3名-Horie R, 他3名
- Journal Title
  
  Leuk Res 30(1)
  
  Pages: 90-7
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] DHMEQ, a new NF-κB inhibitor induces apoptosis of chronic lymphocytic leukemia cells and enhances effect of fludarabine2006
- Author(s)
  Horie R
- Journal Title
  
  Leukemia (印刷中)
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] DHMEQ, a new NF-κB inhibitor induces apoptosis of chronic lymphocytic leukemia cells and enhances effect of fludarabine2006
- Author(s)
  Horie R, Watanabe M, Okamura T, et. al.,
- Journal Title
  
  Leukemia 20
  
  Pages: 800-806
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] DHMEQ, a new NF-κB inhibitor induces apoptosis of chronic Lymphocytic leukemia cells and enhances effect of fludarabine2006
- Author(s)
  Horie R, Watannbe M, Okamura T, Taira M, Higashihara M, Watanabe T, Umezawa K
- Journal Title
  
  Leukemia 20
  
  Pages: 800-806
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] Transactivation of the ICAM-1 gene by CD30 in Hodgkin's Lymphoma.2006
- Author(s)
  Uchihara JN, Matsuda T, Okudaira T, Ishikawa C, Masuda M, Horie R, Watanabe T, Ohta T, Takasu N, Mori N
- Journal Title
  
  International Journal of Cancer 118
  
  Pages: 1098-1107
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] In vitro and in vivo antitumor activity of the NF-kB inhibitor DHMEQ in the human T-cell leukemia virus type 1-transformed cell line, Hut-1022006
- Author(s)
  Ohsugi T, Kumasaka T, Ishida A, Ishida T, Horie R, Watanabe T, Umezawa K, Yamaguchi K.
- Journal Title
  
  Leukemia Research 30
  
  Pages: 90-97
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] In vitro and in vivo antitumor activity of the NF-κB inhibitor DHMEQ in the human T-cell leukemia virus type 1-transformed cell line, HUT-1022006
- Author(s)
  Ohsugi T, Kumasaka T, Ishida A, Ishida T, Horie R, Watanabe T, Umezawa K, Yamaguchi K
- Journal Title
  
  Leukemia Research 30
  
  Pages: 90-97
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] In vitro and in vivo antitumor activity of the NF-kappaB inhibitor DHMEQ in the human T-cell leukemia virus type I-infected cell line, HUT-102.2006
- Author(s)
  Ohsugi T-3名-, Horie R 他3名
- Journal Title
  
  Leuk Res. 30(1)
  
  Pages: 90-7
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] DHMEQ, a new NF-kB inhibitor induces apoptosis of chronic lymphocytic leukemia cells and enhances effect of fludarabine2006
- Author(s)
  Horie R, Watanabe M, Okamura T, Taira M, Higashihara M, Watanabe T, Umezawa K
- Journal Title
  
  Leukemia 20
  
  Pages: 800-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] DHMEQ, a new NF-kappaB inhibitor, induces apoptosis and enhances fludarabine effects on chronic lymphocytic leukemia cells2006
- Author(s)
  Horie, R, Watanabe, M, Okamura, T, Taira, M, Shoda, M, Motoji, T, Utsunomiya, A, Watanabe, T, Higashihara, M, Umezawa, K
- Journal Title
  
  Leukemia 20
  
  Pages: 800-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] DHMEQ, a new NF-kB inhibitor induces apoptosis of chronic lymphocytic2006
- Author(s)
  Horie R, Watanabe M, Okamura T, Taira M, Higashihara M, Watanabe T, Umezawa K.
- Journal Title
  
  Leukemia 20
  
  Pages: 800-806
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] Hodgkin's lymphoma cells are efficiently engrafted and expressed tumor marker CD30 with constitutive NF-kB activity in unconditioned NOD-SCID/gcnull (NOG) mice2006
- Author(s)
  Dewan Md.Z, Watanabe M, Ahmed S, Terashima K, Horiuchi S, Sata T, Honda M, Ito M, Watanabe T, Horie R, Yamamoto N.
- Journal Title
  
  Cancer Sci 96
  
  Pages: 466-473
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] Transactivation of the ICAM-1 gene by CD30 in Hodgkin''s Lymphoma2006
- Author(s)
  Uchihara JN, Matsuda T, Okudaira T, Ishikawa C, Masuda M, Horie R, Watanabe T, Ohta T, Takasu N, Mori N.
- Journal Title
  
  International Journal of cancer 118
  
  Pages: 1098-1107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Journal Article] Transactivation of the ICAM-1 gene by CD30 in Hodgkin's lymphoma.2006
- Author(s)
  Uchihara JN-4名, Horie R 他4名
- Journal Title
  
  Int J Cancer. 118(5)
  
  Pages: 1098-107
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] Transactivation of the ICAM-1 gene by CD30 in Hodgkin's Lymphoma.2006
- Author(s)
  Uchihara JN, Matsuda T, Okudaira T, Ishikawa C, Masuda M, Horie R, Watanabe T, Ohta T, Takasu N, Mori N.
- Journal Title
  
  Int J Cancer 118
  
  Pages: 1098-1107
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] DHMEQ, a new NF-kB inhibitor induces apoptosis of chronic lymphocytic leukemia cells and enhances effect of fludarabine2006
- Author(s)
  Horie R et al.
- Journal Title
  
  Leukemia 20
  
  Pages: 800-806
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] Blocking NF-kappaB as a potential strategy to treat adult T-cell leukemia/lymphoma.2006
- Author(s)
  Horie R, Watanabe T, Umezawa K
- Journal Title
  
  Drug News Perspect 19(4)
  
  Pages: 201-9
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] Blocking NF-kappaB as a potential strategy to treat adult T-cell leukemia/lymphoma2006
- Author(s)
  Horie, R, Watanabe, T, Umezawa, K
- Journal Title
  
  Drug News Perspect
  
  Pages: 201-209
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] DHMEQ, a new NF-kappaB inhibitor, induces apoptosis and enhances fludarabine effects on chronic lvmnhocvtic leukemia cells.2006
- Author(s)
  Horie R 他9名
- Journal Title
  
  Leukemia 20(5)
  
  Pages: 800-6
- Data Source
  KAKENHI-PROJECT-18590345
[Journal Article] JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD302005
- Author(s)
  Watanabe M, (7名略), Horie R.
- Journal Title
  
  Cancer Res. 65(17)
  
  Pages: 7628-34
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] In vivo Antitumor Activity of the NF-_B Inhibitor Dehydroxymethylepoxy-quinomicin in a Mouse Model of Adult T-cell Leukemia2005
- Author(s)
  Ohsugi T, Horie R, Kumasaka T, Ishida A, Ishida T, Yamaguchi K, Watanabe T, Umezawa K, Urano T
- Journal Title
  
  Carcinogenesis 26
  
  Pages: 1382-1388
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] JunB induced by constitutive CD30-extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase signaling activates the CD30 promoter in anaplastic large cell lymphoma and reed-sternberg cells of Hodgkin lymphoma.2005
- Author(s)
  Watanabe M, Sasaki M, Itoh K, Higashihara M, Umezawa K, Kadin ME, Abraham LJ, Watanabe T, Horie R.
- Journal Title
  
  Cancer Res. 65
  
  Pages: 7628-7634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Duel targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ,----.2005
- Author(s)
  Watanabe M, (16名略), Horie R.
- Journal Title
  
  Blood. 106(7)
  
  Pages: 2462-2471
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] A novel NF-kB inhibitor DHMEQ selectively targets constitutive NF-kB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo.2005
- Author(s)
  Watanabe M, (12名略), Horie R.
- Journal Title
  
  Int J Cancer. 114(1)
  
  Pages: 32-38
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ, a potent and selective inhibitor of NF-{kappa}B, as a strategy for chemoprevention and therapy of adult T-cell leukemia.2005
- Author(s)
  Watanabe M, Ohsugi T, Shoda M, Ishida T, Aizawa S, Maruyama-Nagai M, Utsunomiya A, Koga S, Yamada Y, Kamihira S, Okayama A, Kikuchi H, Uozumi K, Yamaguchi K, Higashihara M, Umezawa K, Watanabe T, Horie R.
- Journal Title
  
  Blood 106
  
  Pages: 2462-2471
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Aberrant NF-kB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts.2005
- Author(s)
  Nonaka M, Horie R, (16名略), Yamaoka S
- Journal Title
  
  Oncogene 24(4)
  
  Pages: 3976-86
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Aberrant NF-kB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts2005
- Author(s)
  Nonaka M, Horie R, Itoh K, Watanabe T, Yamamoto N, Yamaoka S.
- Journal Title
  
  Oncogene 24
  
  Pages: 3976-3986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] Aberrant NF-kB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts2005
- Author(s)
  Nonaka M, Horie R, Itoh K, et al.
- Journal Title
  
  Oncogene (in press)
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] Hodgkin's lymphoma cells are efficiently engrafted and tumor marker CD30 is expressed with constitutive NF-kappaB activity in unconditioned -----.2005
- Author(s)
  Dewan MZ, (8名略), Horie R, Yamamoto N.
- Journal Title
  
  Cancer Sci. 96(8)
  
  Pages: 466-473
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] JunB induced by constitutive CD30-extracellular single-regulated kinase 1/2mitogen-activatedproteinkinasesignalingactivates the CD30 promoter----2005
- Author(s)
  Watanabe M, (7名略), Horie R
- Journal Title
  
  Cancer Res. 65(17)
  
  Pages: 7628-7634
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Aberrant NF-kB2/p52 expression in Hodgkin/Reed-Sternberg cells and CD30-transformed rat fibroblasts.2005
- Author(s)
  Nonaka M, Horie R, Itoh K, Watanabe T, Yamamoto N, Yamaoka S
- Journal Title
  
  Oncogene 24
  
  Pages: 3976-3986
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] A novel NF-kappaB inhibitor DHMEQ selectively targets constitutive NF-kappaB activity and induces apoptosis of multiple-myelome cells in vitro and in and in vivo2005
- Author(s)
  Watanabe M--10名--Horie R.
- Journal Title
  
  Int J Cancer. 114(1)
  
  Pages: 32-38
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] A novel NF-kB inhibitor DHMEQ selectively targets constitutive NF-kB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo.2005
- Author(s)
  Watanabe M, Dewan MZ, Okamura T, Sasaki M, Itoh K, Higashihara M, Mizoguchi H, Honda M, Sata T, Watanabe T, Yamamoto N, Umezawa K, Horie R.
- Journal Title
  
  Int J Cancer. 114
  
  Pages: 32-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] A novel NF-kB inhibitor DHMEQ selectively targets constitutive NF-kB activity and induces apoptosis of multiple myeloma cells in vitro and in vivo2005
- Author(s)
  Watanabe M, Dewan Z, Okamura T, Sasaki M, Itoh K, Higashihara M, Mizoguchi H, Honda M, Sata T, Watanabe T, Yamamoto N, Umezawa K, Horie R
- Journal Title
  
  Int J Cancer 114
  
  Pages: 32-38
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] Elevated expression of CD30 in adult T-cell leukemia cell lines : possible role in constitutive NF-kB activation2005
- Author(s)
  Higuchi M, Matsuda T, Mori N, Yamada Y, Horie R, Watanabe T, Takahashi M, Oie M, Fujii M
- Journal Title
  
  Retrovirology 2(epub)
  
  Pages: 29-29
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] JunB induced by constitutive CD30-ERK1/2 MAPK signaling activates the CD30 promoter in anaplastic large cell lymphoma and Reed-Sternberg cells of Hodgkin lymphoma2005
- Author(s)
  Watanabe M, Sasaki M, Itoh K, Higashihara M, Umezawa K, Kadin ME, Abraham LJ, Watanabe T, Horie R.
- Journal Title
  
  Cancer Res 65
  
  Pages: 7628-7634
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] A novel NF-kB inhibitor DHMEQ selectively targets constitutive NF-k B activity and induces apoptosis of multiple mveloma cells in vitro a2005
- Author(s)
  Watanabe M, (12名略), Horie R.
- Journal Title
  
  Int J Cancer. 114(1)
  
  Pages: 32-8
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Dual targeting of transformed and untransformed HTLV-1-infected T cells by DHMEQ,-----.2005
- Author(s)
  Watanabe M, (16名略), Horie R.
- Journal Title
  
  Blood 106(7)
  
  Pages: 2462-71
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Dual targeting of transformed untransformed HTLV- 1-infected T-cells by DHMEQ, a potent and selective inhibitor of NF-kB, as a strategy for chemoprevention and therapy of adult T cell leukemia2005
- Author(s)
  Watanabe M, Ohsugi T, Shoda M, Ishida T, Aizawa S, Maruyama-Nagai M, Utsunomiya A, Koga S, Yamada Y, Kamihira S, Okayama A, Kikuchi H, Uozumi K, Yamaguchi K, Higashihara M, Umezawa K, Watanabe T, Horie R
- Journal Title
  
  BLOOD 106
  
  Pages: 2462-2471
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] In vivo antitumor activity of the NF-kappaB inhibitor dehydroxymethylepoxyquinomicin in a mouse model of adult T-cell leukemia.2005
- Author(s)
  Ohsugi T, Horie R, (6名), Urano T.
- Journal Title
  
  Carcinogenesis. 26(8)
  
  Pages: 1382-1388
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-kB activation in anaplastic large cell lymphoma2004
- Author(s)
  Horie R
- Journal Title
  
  Cancer Cell 5
  
  Pages: 353-364
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Journal Article] The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-kB activation in anaplastic large cell lymphoma.2004
- Author(s)
  Horie R, Watanabe M, Ishida T, Koiwa T, Aizawa S, Ito K, Higashihara M, Kadin E, Watanabe T
- Journal Title
  
  Cancer Cell 5
  
  Pages: 353-364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-kappaB activation in anaplastic large cell lymphoma.2004
- Author(s)
  Horie R--他10名
- Journal Title
  
  Cancer Cells. 5(4)
  
  Pages: 353-364
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Prompt tumor formation and maintenance of constitutive NF-kappaB activity of multiple myeloma cells in NOD/SCID/gammacnull mice.2004
- Author(s)
  Dawan MZ--8名--Horie R, Yamamoto N.
- Journal Title
  
  Cancer Sci. 95(7)
  
  Pages: 564-568
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Rapid Tumor Death Model for Evaluation of New Therapeutic Agents for Adult T-cell Leukemia2004
- Author(s)
  Takeo Ohsugi, Kazunari Yamaguchi, Toshio Kumasaka, Takaomi Ishida, Ryouichi Horie, Toshiki Watanabe, Noboru Sakio, Toshio Fujimoto, Noriyuki Sakamoto, Toru Urano
- Journal Title
  
  Lab Invest 84
  
  Pages: 263-266
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16390103
[Journal Article] Rapid tumor death model for evaluation of new therapeutic agents for adult T-cell leukemia.2004
- Author(s)
  Ohsugi T, Yamaguchi K, Kumasaka T, Ishida T, Horie R, Watanabe T, Sakio N, Fujimoto T, Sakamoto N, Urano T.
- Journal Title
  
  Lab Invest. 84
  
  Pages: 263-266
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-κB activation in anaplastic large cell lymphoma2004
- Author(s)
  Horie R, Watanabe M, Ishida T, Koiwa T, Aizawa S, Itoh K, Higashihara M, Kadin ME, Watanabe T.
- Journal Title
  
  Cancer Cell 5
  
  Pages: 353-364
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Journal Article] The NPM-ALK oncoprotein abrogates CD30 signaling and constitutive NF-kappaB activation in anaplastic large cell lymphoma.2004
- Author(s)
  Horie R, 他10名
- Journal Title
  
  Cancer Cell. 5(4)
  
  Pages: 353-64
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Rapid tumor death model for evaluation of new therapeutic agents for adult T cell leukemia.2004
- Author(s)
  Ohsugi T--3名--Horie R--4名--Urano T.
- Journal Title
  
  Lap Invest. 84(2)
  
  Pages: 263-266
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] Rapid tumor death model for evaluation of new therapeutic agents for adult T-cell leukemia.2004
- Author(s)
  Ohsugi T, 3名, Horie R, 4名, Urano T.
- Journal Title
  
  Lab Invest. 84(2)
  
  Pages: 263-6
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590294
[Journal Article] AP-1 mediated relief of repressive activity of the CD30 promoter microsatellite in Hodgkin and Reed-Sternberg cells.2003
- Author(s)
  Watanabe M, Ogawa Y, Ito K, Higashihara M, Kadin ME, Abraham LJ, Watanabe T, Horie R
- Journal Title
  
  Am J Pathol 163
  
  Pages: 633-641
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Journal Article] Ligand-independent signaling by overexpressed CD30 drivers NF-kB activation in Hodgkin-Reed Sternberg cells.2002
- Author(s)
  Horie R
- Journal Title
  
  Oncogene 21
  
  Pages: 2493-2503
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Journal Article] Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cells2002
- Author(s)
  Horie R
- Journal Title
  
  Am J Pathol 160
  
  Pages: 1647-1654
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Journal Article] Ligand-independent signaling by overexpressed CD30 drives NF-κB activation in Hodgkin-Reed Sternberg cells.2002
- Author(s)
  Horie R, Watanabe T, Morishita Y, Ito K, Ishida T, Kanegae Y, Saito I, Higashihara M, Mori S, Kadin ME, Watanabe T.
- Journal Title
  
  Oncogene 21
  
  Pages: 2493-2503
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Journal Article] Cytoplasmic aggregation of TRAF2 and TRAF5 proteins in the Hodgkin-Reed-Sternberg cells2002
- Author(s)
  Horie R, Watanabe T, Ito K, Morisita Y, Watanabe M, Ishida T, Higashihara M, Kadin M, Watanabe T.
- Journal Title
  
  Am J Pathol 160
  
  Pages: 1647-1654
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-14370067
[Patent] NF-κB阻害剤2017
- Inventor(s)
  堀江良一他６名
- Industrial Property Rights Holder
  学校法人北里研究所
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2017-181123
- Filing Date
  2017
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] CD30によるHTLV-1感染細胞株における多核細胞の誘導機構2023
- Author(s)
  堀江良一、渡邉真理子、初瀬洋美、長尾和右、大津真、宮崎浩二、渡邉俊樹
- Organizer
  第9回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06429
[Presentation] CD30シグナルが誘導する染色体不安定性の促進機構2022
- Author(s)
  中島誠,宇都宮與,渡邉俊樹,堀江良一,内丸薫
- Organizer
  第81回日本癌学会学術総会　横浜
- Data Source
  KAKENHI-PROJECT-20K07379
[Presentation] ホジキンリンパ腫細胞の活性酸素による分化とHIF-1αを介したヘムオキシダーゼ1による分化制御2021
- Author(s)
  堀江良一、中島誠、渡邊真理子、中野和民、内丸薫.
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07442
[Presentation] ホジキンリンパ腫細胞の活性酸素による分化とHIF-1αを介したヘムオキシダーゼ1による分化制御2021
- Author(s)
  堀江良一、中島誠、渡邊真理子、中野和民、内丸薫
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07379
[Presentation] 成人T細胞白血病リンパ腫においてCD30シグナルは染色体不安定性を高める2021
- Author(s)
  中島誠、宇都宮與、渡邉俊樹、堀江良一、内丸薫
- Organizer
  第83回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07379
[Presentation] ホジキンリンパ腫細胞のROSによる分化とHIF-1αを介したヘムオキシダーゼ1による分化制御2020
- Author(s)
  中島誠、渡邊真理子、中野和民、内丸薫、堀江良一
- Organizer
  第8２回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07442
[Presentation] ホジキンリンパ腫細胞のROSによる分化とHIF-1αを介したヘムオキシダーゼ1による分化制御2020
- Author(s)
  中島誠、渡邉真理子、中野和民、内丸薫、堀江良一
- Organizer
  第82回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-20K07379
[Presentation] 活性酸素種によるホジキンリンパ腫細胞の分化とHIF-1αを介したHeme Oxygenase 1による分化制御機構2019
- Author(s)
  中島誠、渡邉真理子、中野和民、内丸薫、堀江良一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] 活性酸素種によるホジキンリンパ腫細胞の分化とHIF-1αを介したHeme Oxygenase 1による分化制御機構2019
- Author(s)
  中島誠、渡邊真理子、中野和民、内丸薫、堀江良一
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K07442
[Presentation] CD30陽性HTLV-1感染細胞の特徴とブレンツキシマブベドチンの効果について2018
- Author(s)
  中島誠、矢持忠徳、渡邊真理子、宇都宮與、東原正明、渡邉俊樹、内丸薫、堀江良一
- Organizer
  第80回日本血液学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] トロゴサイトーシスによるCD30 リガンド・レセプター複合体の細胞内移行機構の解析2018
- Author(s)
  Makoto Nakashima, Mariko Watanabe, Kaoru Uchimaru1, Ryouichi Horie
- Organizer
  第77回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] CD30リガンド刺激によるCD30+HTLV-1感染細胞の増殖とブレンツキシマブベドチンの効果の解析2018
- Author(s)
  中島誠、矢持忠徳、渡邊真理子、宇都宮與、東原正明、渡邉俊樹、内丸薫、堀江良一
- Organizer
  第5回日本HTLV-1学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] CD30シグナルにおけるリガンド・レセプター複合体の内在化と細胞内輸送2017
- Author(s)
  中島誠、渡邉真理子、内丸薫、堀江良一
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] 古典的Hodgkinリンパ腫におけるCD30を介したHSP90誘導とシグナル伝達制御機構の解析2017
- Author(s)
  渡邉真理子、東原正明、堀江良一
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] 古典的 Hodgkin リンパ腫における CD30 を介した HSP90 誘導シグナル伝達制御機構の解析2017
- Author(s)
  渡邉真理子、東原正明、堀江良一
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] Internalization of ligand-receptor complex and its intracellular transport in CD30 signaling2017
- Author(s)
  Makoto Nakashima, Mariko Watanabe, Kaoru Uchimaru, Ryouich Horie
- Organizer
  第79回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] 古典的Hodgkinリンパ腫におけるCD30を介したHSP90誘導とシグナル統合機構の解析2017
- Author(s)
  堀江良一、渡邉真理子、内丸薫、中野和民、Marshall E. Kadin、渡邉俊樹、東原正明
- Organizer
  第57回日本リンパ網内系学会総会
- Data Source
  KAKENHI-PROJECT-17K08728
[Presentation] 成人T細胞性白血病におけるCD30陽性集団に高倍数体細胞は出現する2016
- Author(s)
  中島誠、矢持忠徳、渡邉真理子、内丸薫、宇都宮與、東原正明、渡邉俊樹、堀江良一
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島県市町村自治会館（鹿児島県鹿児島市）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26460440
[Presentation] 古典的Hodgkinリンパ腫におけるCD30を介したHSP90誘導とシグナル統合機構の解析2016
- Author(s)
  堀江良一、渡邉真理子、内丸薫、中野和民、Marshall E. Kadin、渡邉俊樹、東原正明
- Organizer
  第56回日本リンパ網内系学会
- Place of Presentation
  ホテル日航熊本 (熊本県熊本市 ) (誌上発表)
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26460440
[Presentation] 古典的Hodgkinリンパ腫におけるCD30を介したHSP90誘導とシグナル統合機構の解析2016
- Author(s)
  堀江良一、渡邉真理子、内丸薫、中野和民、Marsha ll E. Kadin、、渡邉俊樹、東原正明
- Organizer
  第56回日本リンパ網内系学会
- Place of Presentation
  ホテル日航熊本（熊本県熊本市）（誌上発表）
- Year and Date
  2016-09-01
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] 成人T細胞性白血病におけるCD30陽性集団に高倍数体細胞は出現する2016
- Author(s)
  中島誠、矢持忠徳、渡邉真理子、内丸薫、宇都宮與、東原正明、渡邉俊樹、堀江良一
- Organizer
  第3回日本HTLV-1学会学術集会
- Place of Presentation
  鹿児島県市町村自治会館（鹿児島県鹿児島市）
- Year and Date
  2016-08-26
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] The emergence of hyperploid cells in CD30+ subpopulation of adult T-cell leukemia.2016
- Author(s)
  Makoto Nakashima, Tadanori Yamochi, Ma riko Watanabe, Atae Utsunomia, Masaaki Higashihara, Kaoru Uchimaru, Toshiki Watanabe, Ryouichi Horie
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] The emergence of hyperploid cells in CD30+ subpopulation of adult T-cell leukemia2016
- Author(s)
  Makoto Nakashima, Tadanori Yamochi, Mariko Watanabe, Atae Utsunomia, Masaaki Higashihara, Kaoru Uchimaru, Toshiki Watanabe, Ryouichi Horie
- Organizer
  第78回日本血液学会
- Place of Presentation
  パシフィコ横浜（神奈川県横浜市）
- Year and Date
  2016-10-13
- Data Source
  KAKENHI-PROJECT-26460440
[Presentation] Differential effects of Brefeldin A on anaplastic large cell lymphoma and Hodgkin lymphoma2015
- Author(s)
  堀江良一、戸田崇史、渡邉真理子、河戸淳仁、Marshall E. Kadin、梅澤一夫、東原正明
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県・金沢市
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] ALK陽性未分化大細胞型リンパ腫と古典的Hodgkinリンパ腫細胞株に対して異なる感受性を示す薬剤の探索とBrefeldin Aの同定2015
- Author(s)
  堀江良一、戸田崇史、渡邉真理子、河戸淳仁、梅澤一夫、東原正明
- Organizer
  第55回日本リンパ網内系学会総会
- Place of Presentation
  岡山コンベンションセンター（岡山県・岡山市）
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26460440
[Presentation] ALK陽性未分化大細胞型リンパ腫と古典的Hodgkinリンパ腫細胞株に対して異なる感受性を示す薬剤の探索とBrefeldin Aの同定2015
- Author(s)
  堀江良一、戸田崇史、渡邉真理子、河戸淳仁、梅澤一夫、東原正明
- Organizer
  第54回日本リンパ網内系学会総会
- Place of Presentation
  岡山県・岡山市
- Year and Date
  2015-06-21
- Data Source
  KAKENHI-PROJECT-26460439
[Presentation] Differential effects of Brefeldin A on anaplastic large cell lymphoma and Hodgkin lymphoma2015
- Author(s)
  堀江良一、戸田崇史、渡邉真理子、河戸淳仁、Marshall E. Kadin、梅澤一夫、東原正明
- Organizer
  第77回日本血液学会学術集会
- Place of Presentation
  石川県立音楽堂他（石川県・金沢市）
- Year and Date
  2015-10-16
- Data Source
  KAKENHI-PROJECT-26460440
[Presentation] Hodgkinリンパ腫細胞の分化と癌幹細胞. シンポジウムIII 「Hodgkinリンパ腫の分子機構の解明と新たな治療戦略」2014
- Author(s)
  堀江良一
- Organizer
  第54回日本リンパ網内系学会総会
- Place of Presentation
  山形国際ホテル（山形）
- Year and Date
  2014-06-20
- Invited
- Data Source
  KAKENHI-PROJECT-26460440
[Presentation] Hodgkinリンパ腫と未分化大細胞型リンパ腫におけるCD30過剰発現機構の解析2013
- Author(s)
  堀江良一, 渡邉真理子, 伊藤金次, 栂野富輝, KADIN Marshall E, 渡邉俊樹, 東原正明
- Organizer
  第53回日本リンパ網内系学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Hodgkinリンパ腫と未分化大細胞型リンパ腫におけるCD30過剰発現機構の解析2013
- Author(s)
  堀江良一, 渡邉真理子, 伊藤金次, 栂野富輝, KADIN Marshall E, 渡邉俊樹, 東原正明
- Organizer
  第53回日本リンパ網内系学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] CD30 repression triggers global gene responses and anti-proliferative effects in Hodgkin lymphoma2013
- Author(s)
  堀江良一, 渡邉真理子, 中野和民, 栂野富輝, Marshall E. Kadin, 渡邉俊樹, 東原正明
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] he regulation of ''inflammatory niche'' with tumor derived small RNAs2013
- Author(s)
  山川奈津子, 横山和明, Jun Lu, 今留謙一, 渡辺俊樹, 堀江良一, 穂積勝人, 八幡崇, 安藤潔, 中村直哉, 幸谷愛
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] The regulation of ''inflammatory niche'' with tumor derived small RNAs2013
- Author(s)
  山川奈津子, 横山和明, Jun Lu, 今留謙一, 渡辺俊樹, 堀江良一, 穂積勝人, 八幡崇, 安藤潔, 中村直哉, 幸谷愛
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2013-10-11
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] CD30 repression triggers global gene responses and anti-proliferative effects in Hodgkin lymphoma2013
- Author(s)
  堀江良一, 渡邉真理子, 中野和民, 栂野富輝, Marshall E. Kadin, 渡邉俊樹, 東原正明
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Year and Date
  2013-10-12
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Hodgkinリンパ腫と未分化大細胞性リンパ腫におけるCD30過剰発現機構の解析2012
- Author(s)
  堀江良一, 渡邉真理子, 伊藤金次, 栂野富輝, Kdin E Marshall, 渡邉俊樹, 東原正明
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Molecular mechanisms of CD30 overexpression in Hodgkin’s lymphoma and anaplastic large-cell lymphoma2012
- Author(s)
  Ryouichi Horie, Mariko Watanabe, Kinji Itoh, Tomiteru Togano, Marshall E. Kadin, Toshiki Watanabe, Masaaki Higashihara
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] The function of small RNAs conjugated in exosome in inflammatory niche of EBV positive lymphoma2012
- Author(s)
  Ai Kotani, Jen Lu, Toshiki Watanabe, Ryoichi Horie, Kiyoshi Ando, Naoya Nakamura
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] The function of small RNAs conjugated in exosome in inflammatory niche of EBV positive lymphoma2012
- Author(s)
  Ai Kotani, Jen Lu, Toshiki Watanabe, Ryoichi Horie, Kiyoshi Ando, Naoya Nakamura
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-20
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Molecular mechanisms of CD30 overexpression in Hodgkin’s lymphoma and anaplastic large-cell lymphoma2012
- Author(s)
  Ryouichi Horie, Mariko Watanabe, Kinji Itoh, Tomiteru Togano, Marshall E. Kadin, Toshiki Watanabe, Masaaki Higashihara
- Organizer
  日本血液学会第74回日本血液学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] Hodgkinリンパ腫と未分化大細胞性リンパ腫におけるCD30過剰発現機構の解析2012
- Author(s)
  堀江良一, 渡邉真理子, 伊藤金次, 栂野富輝, Kdin E Marshall, 渡邉俊樹, 東原正明
- Organizer
  第74回日本血液学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-10-21
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] Hodgkinリンパ腫の前駆細胞における分子基盤の解析と分子標的療法の基礎的検討2011
- Author(s)
  堀江良一, 中島誠, 渡邉真理子, 栂野冨輝, 梅澤一夫, 渡邉俊樹, 東原正明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Hodgkinリンパ腫の前駆細胞における分子基盤の解析と分子標的療法の基礎的検討2011
- Author(s)
  堀江良一、中島誠、渡邉真理子、栂野冨輝、梅澤一夫、渡邉俊樹、東原正明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] EBV陽性リンパ腫微小環境における分泌性EBVコードmiRNA2011
- Author(s)
  井上優希, 中村直哉, 阿部幸一郎, 豊嶋孝恵, 堀江良一, 渡邉俊樹, 安藤潔, 幸谷愛
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Hodgkinリンパ腫の前駆細胞における分子基盤の解析と分子標的療法の基礎的検討2011
- Author(s)
  堀江良一、中島誠、渡邉真理子、栂野冨輝、梅澤一夫、渡邉俊樹、東原正明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋国際会議場
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] Side populationはHodgkin,Reed‐Sternberg細胞の前駆細胞集団でNF‐κB阻害薬DHMEQの標的となる。2011
- Author(s)
  堀江良一, 中島誠, 石井有実子, 渡邉真理子, 栂野富輝, 渡邉俊樹, 梅澤一夫, 東原正明
- Organizer
  第51回日本リンパ網内系学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] Hodgkinリンパ腫の前駆細胞における分子基盤の解析と分子標的療法の基礎的検討2011
- Author(s)
  堀江良一, 中島誠, 渡邉真理子, 栂野冨輝, 梅澤一夫, 渡邉俊樹, 東原正明
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] EBV陽性リンパ腫微小環境における分泌性EBVコードmiRNA2011
- Author(s)
  井上優希, 中村直哉, 阿部幸一郎, 豊嶋孝恵, 堀江良一, 渡邉俊樹, 安藤潔, 幸谷愛
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-15
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] Side populationはHodgkin,Reed‐Sternberg細胞の前駆細胞集団でNF‐κB阻害薬DHMEQの標的となる。2011
- Author(s)
  堀江良一,中島誠,石井有実子,渡邉真理子,栂野富輝,渡邉俊樹,梅澤一夫,東原正明
- Organizer
  第51回日本リンパ網内系学会総会
- Place of Presentation
  福岡
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] Affect of aberrant T cell antigen expewssion on DLBCL patients'backgrownd and prognosis2010
- Author(s)
  Suzuki Y(13名)Horie R, Higashihara M
- Organizer
  第72回日本血液学会学術集会
- Place of Presentation
  パシフィコ横浜(神奈川県)
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] Affect of aberrant T cell antigenexpression on DLBCL patients'background and prognosis.2010
- Author(s)
  Suzuki Y.,(13名)Horie R, Higashihara M
- Organizer
  第72回日本血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] Identification of the RelA domainresponsible for the action of a newNF-kB inhibitor DHMEQ2009
- Author(s)
  RyouichiHorie, (3名)Masaaki Higashihara, Toshiki Watanabe, Kazuo Umezawa
- Organizer
  第71回日本血液学会学術総会
- Place of Presentation
  京都
- Year and Date
  2009-10-23
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] NF-kB阻害剤DHMEQの標的分子と核への分布を阻害するドメインの同定2009
- Author(s)
  堀江良一, (他6名)
- Organizer
  第13回日本がん分子標的治療研究会学術集会
- Place of Presentation
  徳島
- Year and Date
  2009-06-26
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] CD30プロモーターメチル化とJunBを介したCD30誘導機構の解析2008
- Author(s)
  堀江良一、(7名)東原正明
- Organizer
  第67回日本癌学会学術総会
- Place of Presentation
  名古屋
- Year and Date
  2008-10-30
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] CD30プロモーターメチル化とJunBを介したCD30誘導機構の解析2008
- Author(s)
  堀江良一, 他7名
- Organizer
  日本血液学会総会
- Place of Presentation
  京都国際会館
- Year and Date
  2008-10-12
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] 難治性リンパ系悪性腫瘍におけるNF一κBシグナル伝達への阻害剤の応用2008
- Author(s)
  堀江良一
- Organizer
  第12回がん分子標的治療学会シンポジウム招待講演
- Place of Presentation
  東京
- Year and Date
  2008-06-28
- Data Source
  KAKENHI-PROJECT-20590374
[Presentation] 変異型lkBaを有するH-RS細胞でのIkBbを介したNF-kB誘導とDHMEQによる分子標的療法2007
- Author(s)
  堀江良一、渡邉真理子、Dewan MdZ, 他
- Organizer
  第69回日本血液学会第49回日本臨床血液学会合同総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] 変異型IkBaを有するH-RS細胞でのlkBbを介したNF・kB誘導とDHMEQによる分子標的療法2007
- Author(s)
  堀江良一、渡邉真理子、Dewan MdZ, 他
- Organizer
  第69回日本血液学会第49回日本臨床血液学会合同総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-11
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] IkBb mediated NF-kB induction in H-RS cells bearring mutant IkBa and its inhibition by DHMEQ2007
- Author(s)
  堀江良一、渡邉真理子、Dewan MdZ, 他
- Organizer
  第66向日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-03
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] IkBb mediated NF-kB induction in H-RS cells bearing mutant IkBa and its Inhibition by DHMEQ2007
- Author(s)
  Horie R, Watanabe M, Dewan MdZ, et. al.
- Organizer
  The 66th Annual Meeting of the Japanese Cancer Association
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] Transient inhibition of NF-kB by DHMEQ in primary effusion lymphoma destroys cancer cells without induction of viral replication.2007
- Author(s)
  Dabaghmanesh N, 三宅在子、堀江良一、Dewan MdZ, 山本直樹、渡邉俊樹
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2007-10-22
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] Transient inhibition of NF-kBby DHMEQ in primary effusion lymphoma destroys cancer cells with outinduction of viral relication2007
- Author(s)
  Nazanin D, 三宅在子、堀江良一、Dewan MdZ, 山本直樹、渡邉俊樹
- Organizer
  第55回日本ウイルス学会学術集会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2007-10-22
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] IkBb mediated NF-kB induction in H-RS cells bearing mutant IkBa and its inhibition by DHMEQ DHMEQ, a new NF-kB inhibitor induces apoptosis2007
- Author(s)
  Horie R, Watanabe M, Dewan MdZ, et. al.
- Organizer
  The 69th Annual Meeting of the Japanese Society of Hematology, the 49th Annual Meeting of the Japanese Society of clinical Hematology
- Place of Presentation
  Yokohama, Japan
- Year and Date
  2007-10-11
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] IkBb mediated NF-kB induction in H-RS cells bearing mutant IkBa and its inhibition by DHMEQ2007
- Author(s)
  堀江良一、渡邉真理子、Dewan MdZ、, 他
- Organizer
  第66回日本癌学会学術総会
- Place of Presentation
  パシフィコ横浜、横浜
- Year and Date
  2007-10-03
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] 変異型IkBaを有するH-RS細胞でのIkBbを介したNF-kB誘導とDHMEQによる分子標的療法2007
- Author(s)
  堀江良一, 他8名
- Organizer
  第49回日本臨床血液学会総会
- Place of Presentation
  横浜
- Year and Date
  2007-10-12
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Presentation] Transient inhibition of NF-kB by DI-IMEQ in primary effusion lymphoma destroys cancer cells without induction of viral replication2007
- Author(s)
  Debaghmanesh N, Miyake A, Horie R., Dewan MdZ, Yamamoto N, Watanabe T.
- Organizer
  The 55th Annual Meeting of the Japanese Society for Virology
- Place of Presentation
  Sapporo, Japan
- Year and Date
  2007-10-22
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18390111
[Presentation] Targeting of constitutive NF-KB activation in transformed and untransformed HTLV-1-infected T cells by DHMEQ : A strategy for chemoprevention and therapy of adult T-cell leukemia. Int J Mol. Med2006
- Author(s)
  R., Horie
- Organizer
  The 11th world Congress on Advances in Oncology, 9 th International Symposium on Molecular Medicine
- Place of Presentation
  Hersonissos, Crete, Greece
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590345
[Presentation] Hodgkinリンパ腫と未分化大細胞型リンパ腫におけるCD30過剰発現機構の解析
- Author(s)
  堀江良一、渡邉真理子、伊藤金次、栂野富輝、KADIN Marshall E、渡邉俊樹、東原正明
- Organizer
  第53回日本リンパ網内系学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] CD30 repression triggers global gene responses and anti-proliferative effects in Hodgkin lymphoma
- Author(s)
  堀江良一、渡邉真理子、中野和民、栂野富輝、Marshall E. Kadin、渡邉俊樹、東原正明
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590432
[Presentation] Hodgkinリンパ腫と未分化大細胞型リンパ腫におけるCD30過剰発現機構の解析
- Author(s)
  堀江良一、渡邉真理子、伊藤金次、栂野富輝、Kadin Marshall E、渡邉俊樹、東原正明
- Organizer
  第53回日本リンパ網内系学会総会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590433
[Presentation] CD30 repression triggers global gene responses and anti-proliferative effects in Hodgkin lymphoma
- Author(s)
  堀江良一、渡邉真理子、中野和民、栂野富輝、Marshall E. Kadin、渡邉俊樹、東原正明
- Organizer
  第75回日本血液学会学術集会
- Place of Presentation
  札幌
- Data Source
  KAKENHI-PROJECT-23590433

1. HIGASHIHARA Masaaki (80165084)

# of Collaborated Projects: 8 results

# of Collaborated Products: 20 results
2. WATANABE Toshiki (30182934)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
3. WATANABE MARIKO (90270701)

# of Collaborated Projects: 4 results

# of Collaborated Products: 33 results
4. AOKI Katsunori (40291322)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. ISHIDA Takaomi (80293447)

# of Collaborated Projects: 3 results

# of Collaborated Products: 14 results
6. DANBARA Mikio (80255348)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
7. MIYAZAKI Kouji (90261966)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
8. AKIYAMA Nobu (50286358)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. SUNAGA Shinji (70282621)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. TAKAISHI Masaaki (10256307)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. KANEKO Takako (00286361)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. KAMATA Kouju (20146343)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. NIITSU Nozomi (20256697)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. IKEBE Mitsuo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. SHICHISHIMA Tsutomu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 渡辺俊樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 56 results
17. 清水史郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 廣瀬友靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 梅沢一夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
20. 中島誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 佐藤雄一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

HORIE Ryouichi 堀江 良一

堀江 良一 ホリエ リヨウイチ

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Co-Researchers

Roles of NF-kB activation in tumorigenesis of HTLV-1-infected cells by CD30Principal Investigator

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Genomic instability and tumorigenesis by CD30 in HTLV-1-infected cellsPrincipal Investigator

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Regulation of Hodgkin lymphoma cell differentiation by reactive oxygen speciesPrincipal Investigator

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Signal integration by CD30 through HSP90 in classical Hodgkin lymphomaPrincipal Investigator

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Analyses of molecular bases by LMP-1 and CD30, which mediate transformation of lymphocytes to Hodgkin lymphoma cellsPrincipal Investigator

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Molecular mechanisms of Hodgkin and anaplastic large cell lymhoma triggered by CD30 induction and P80Principal Investigator

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Analysis of molecular basis for occurance of Hodgkin lympnoma and anaplastic large cell lymphomaPrincipal Investigator

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Analyses of phenotypic changes of Hodgkin and Reed-Stemberg cells to anaplastic large cell lymphoma cells by p80.Principal Investigator

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Project Period (FY)

HORIE Ryouichi 堀江良一

堀江良一ホリエリヨウイチ

[Book] 特集　ホジキンリンパ腫2016

[Book] 特集　ホジキンリンパ腫2016

[Book] シグナル伝達　研究最前線　２０１２2012