TOHDA Shuji 東田修二

… Alternative Names

東田修二トウダシュウジ

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Researcher Number	80251510
Other IDs
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Affiliation (Current)	2025: 東京科学大学, 大学院医歯学総合研究科, 教授
Affiliation (based on the past Project Information) *help	2016 – 2022: 東京医科歯科大学, 大学院医歯学総合研究科, 教授 2015: 東京医科歯科大学, 医歯(薬)学総合研究科, 教授 2011 – 2014: 東京医科歯科大学, 医歯(薬)学総合研究科, 准教授 2010: Tokyo Medical and Dental University, 大学院・医歯学総合研究科, 准教授 2009: Tokyo Medical and Dental University, 医歯学総合研究科, 准教授 … More 2007 – 2008: Tokyo Medical and Dental University, Department of Laboratory Medicine, Associate Professor 2006: 東京医科歯科大学, 大学院医歯学総合研究科, 助教授 1999 – 2005: Tokyo Medical and Dental University, Department of Laboratory Medicine, Associate Professor, 大学院・医歯学総合研究科, 助教授 2003: Tokyo Medical and Dental University, Postgraduate School, Associate Professor, 大学院・医歯学総合研究所, 助教授 1997 – 1998: 東京医科歯科大学, 医学部, 講師 1993 – 1995: 東京医科歯科大学, 医学部, 助手 Less
Review Section/Research Field	Principal Investigator Laboratory medicine / Laboratory medicine / Basic Section 52010:General internal medicine-related / Hematology Except Principal Investigator Laboratory medicine / Laboratory medicine
Keywords	Principal Investigator Notch / 白血病 / Delta / Jagged / 白血病幹細胞 / 分子標的薬 / 薬剤感受性検査 / 急性白血病 / 分子標的治療 / acute myeloblastic leukemia … More / G-CSF / 急性骨髄性白血病 / NOTCH / ガンマセクレターゼ / 幹細胞 / 遺伝子パネル検査 / 次世代シークエンサ解析 / 分子標的治療薬 / シグナル蛋白 / コンパニオン検査 / HIF / 低酸素 / コンパニオン診断検査 / Myelodysplastic syndrome / Lymphoma / Gamma-secretase / Molecular-targeting therapy / Leukemia / アポトーシス / 骨髄異形成症候群 / リンパ腫 / leukemia / signal transduction / シグナル伝達 / 自己複製 / MYD88 / BMI1 / Hedgehog / BMP / mTOR / Notchリガンド / 臨床血液学 / 情報伝達系 / 造血因子 … More Except Principal Investigator 急性骨髄性白血病 / サイトカイン / 白血病幹細胞 / Notch Ligand / 残存白血病細胞 / WT-1 gene / acute myelogenous leukemia / WT-1遺伝子 / 白血病 / 制癌剤 / 急性白血病 / Leukemia Cell Line / Molecular-Targeting Therapy / Leukemia / 白血病細胞株 / 分子標的療法 / Gene-targeted Therapy / Residnal Leukemia Cells / Acute Myelovlastiv Leukemia / 遺伝子標的治療 / Jagged protein / Notch protein / IgH gene rearrangement / residual leukemic cells / IgH遺伝子再構成 / Jagged蛋白 / Notch蛋白 / cytokines / leukemic balst progenitors / leukemic cells / T細胞レセプター遺伝子 / 免疫グロブリン重鎖遺伝子 / 白血病コロニー / 白血病細胞 / アポトーシス / 白血病性幹細胞 / 切断点 / 染色体転座 / 悪性リンパ腫 / Zinc finger / Trans cription factor / BCL6 gene / 白血病治療 / 自己再生能 / 造血因子 Less

Development of molecular targeted drug sensitivity tests that integrate gene panel testing and signaling protein analysis for leukemiaPrincipal Investigator
- Principal Investigator
  
  TOHDA Shuji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Tokyo Medical and Dental University
Companion Diagnostics to predict the effects of molecularly-targeted drugs on acute leukemia stem cellsPrincipal Investigator
- Principal Investigator
  
  Tohda Shuji
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Tests for self-renewal signals of acute leukemia stem cells and prediction of the effects of molecular-targeted drugs for the signalsPrincipal Investigator
- Principal Investigator
  
  TOHDA Shuji
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Tests for quantity and characteristics of acute leukemia stem cells to search molecular-targeted therapies suitable for each casePrincipal Investigator
- Principal Investigator
  
  SHUJI TOHDA
- Project Period (FY)
  2011 – 2013
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Role of Notch in the pathophysiology of leukemia stem cells and drug sensitivity tests for Notch inhibitorsPrincipal Investigator
- Principal Investigator
  
  TOHDA Shuji
- Project Period (FY)
  2008 – 2010
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
A novel therapy targeting Notch molecule against leukemia and a method to select patients suitable for the therapyPrincipal Investigator
- Principal Investigator
  
  SHUJI Tohda
- Project Period (FY)
  2006 – 2007
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
The method to surmise the prognosis of leukemia patients by analyzing the function of Notch proteinPrincipal Investigator
- Principal Investigator
  
  TOHDA Shuji
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Study on the System Detecting the Effect of the Molecular-Targeting Therapy for Leukemia and the Patients Prognosis.
- Principal Investigator
  
  NARA Nobuo
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Study on the System Detecting the residual Leukeinic Cells after the Gene-targeted Therapy forLeukemia
- Principal Investigator
  
  MARA Nobuo
- Project Period (FY)
  2002 – 2003
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Development of the method to surmise the prognosis of acute myeloblastic leukemia patients by analyzing the expression of Notch proteinPrincipal Investigator
- Principal Investigator
  
  TOHDA Shuji
- Project Period (FY)
  2001 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
The establishment of the system that predicts the prognosis of acute leukemia patients on the basis of the biological properties of leukemic blast progenitors.
- Principal Investigator
  
  NARA Nobuo
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
Development of the method to infer the responsiveness of acute myeloblastic leukemia cells for G-CSFPrincipal Investigator
- Principal Investigator
  
  TOHDA Shuji
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
The establishment of the method which detects the minimal residual leukemic cells in acute myelogenous patients in remisson and predicts the patients prognosis.
- Principal Investigator
  
  NARA Nobuo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory medicine
- Research Institution
  Tokyo Medical and Dental University
白血病細胞における造血因子の細胞内情報伝達系の解明Principal Investigator
- Principal Investigator
  
  東田修二
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for Encouragement of Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Tokyo Medical and Dental University
B細胞リンパ腫に関与する遺伝子(BCL-5)の同定と発症メカニズムの研究
- Principal Investigator
  
  広沢信作
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
白血病細胞の増殖阻止を目的とした制癌剤とサイトカインの併用療法に関する研究
- Principal Investigator
  
  奈良信雄
- Project Period (FY)
  1994
- Research Category
  
  Grant-in-Aid for Scientific Research on Priority Areas
- Research Institution
  Tokyo Medical and Dental University
白血病細胞の増殖阻止を目的とした制癌剤とサイトカインの併用療法に関する研究
- Principal Investigator
  
  NARA Nobuo
- Project Period (FY)
  1993
- Research Category
  
  Grant-in-Aid for Cancer Research
- Research Institution
  Tokyo Medical and Dental University

[Book] 標準臨床検査医学第5版　（分担）第10章　染色体検査・遺伝子検査2023
- Author(s)
  山田俊幸、大西宏明（編集）、東田修二（分担執筆）
- Total Pages
  448
- Publisher
  医学書院
- ISBN
  9784260049672
- Data Source
  KAKENHI-PROJECT-20K07780
[Book] 臨床検査のガイドラインJSLM20152015
- Author(s)
  東田修二（分担執筆）
- Total Pages
  446
- Publisher
  日本臨床検査医学会
- Data Source
  KAKENHI-PROJECT-26460669
[Book] 遺伝子・染色体検査学2015
- Author(s)
  池内達郎、小原深美子、東田修二、中田章史、奈良信雄、吉田光明
- Total Pages
  244
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-26460669
[Book] 日常診療のための検査値のみかた　-　造血器腫瘍関連染色体・遺伝子検査2015
- Author(s)
  東田修二（分担執筆）
- Total Pages
  757
- Publisher
  中外医学社
- Data Source
  KAKENHI-PROJECT-26460669
[Book] 造血器腫瘍、染色体・遺伝子検査、造血器腫瘍の検査結果の評価・解釈.血液検査学2012
- Author(s)
  東田修二
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590662
[Book] 「血液検査学」造血器腫瘍、染色体・遺伝子検査、造血器腫瘍の検査結果の評価・解釈2012
- Author(s)
  東田修二（分担執筆）
- Total Pages
  32
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590662
[Book] 「顕微鏡検査ハンドブック-臨床に役立つ形態学」BおよびT前駆細胞の腫瘍、成熟B細胞腫瘍、成熟T細胞腫瘍・NK細胞腫瘍2012
- Author(s)
  東田修二（分担執筆）
- Total Pages
  7
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-23590662
[Book] 「遺伝子分析科学」遺伝子検査結果の評価-血液疾患-2011
- Author(s)
  東田修二（分担執筆）
- Total Pages
  257
- Publisher
  宇宙堂八木書店
- Data Source
  KAKENHI-PROJECT-23590662
[Book] 急性白血病、血友病など17項目(福井次矢、奈良信雄編)(内科診断学第2版)2008
- Author(s)
  東田修二
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-20590557
[Book] 可溶性IL-2レセプター、顆粒球コロニー刺激因子など15項目(櫻林郁之介、熊坂一成監修)(最新臨床検査項目辞典)2008
- Author(s)
  東田修二
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-20590557
[Book] 「疾患からまとめた病態生理FIRST AID」急性白血病など2007
- Author(s)
  東田修二(分担執筆)
- Publisher
  メディカル・サイエンス・インターナショナル社
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] <i>TYRO3</i> Knockdown Suppresses the Growth of Myeloid Leukaemia Cells2022
- Author(s)
  SAITO TATSUYA、ITOH MAI、TOHDA SHUJI
- Journal Title
  
  Anticancer Research
  
  Volume: 42 Issue: 4 Pages: 1757-1761
- DOI
  10.21873/anticanres.15652
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07780
[Journal Article] Effects of HOXA9 Inhibitor DB818 on the Growth of Acute Myeloid Leukaemia Cells2021
- Author(s)
  SONODA YURI、ITOH MAI、TOHDA SHUJI
- Journal Title
  
  Anticancer Research
  
  Volume: 41 Issue: 4 Pages: 1841-1847
- DOI
  10.21873/anticanres.14950
- Data Source
  KAKENHI-PROJECT-20K07780
[Journal Article] Sirtuin 1 Activation Suppresses the Growth of T-lymphoblastic Leukemia Cells by Inhibiting NOTCH and NF-κB Pathways2020
- Author(s)
  OKASHA SALWA M.、ITOH MAI、TOHDA SHUJI
- Journal Title
  
  Anticancer Research
  
  Volume: 40 Issue: 6 Pages: 3155-3161
- DOI
  10.21873/anticanres.14297
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07780
[Journal Article] Metformin suppresses the growth of leukemia cells partly through downregulation of AXL receptor tyrosine kinase2020
- Author(s)
  Saito Tatsuya、Itoh Mai、Tohda Shuji
- Journal Title
  
  Leukemia Research
  
  Volume: 94 Pages: 106383-106383
- DOI
  10.1016/j.leukres.2020.106383
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07780
[Journal Article] Chloroquine Inhibits Self-Renewal of Blast Progenitors Synergistically With Phytochemicals or Nonsteroidal Anti-inflammatory Drugs in Hematological Malignant Cell Lines2019
- Author(s)
  KAWAGUCHI-IHARA NORIKO、ZHAO YAN、NAKAMURA SUZUNE、SUZUKI KEIKO、ZHANG YI、TOHDA SHUJI、MUROHASHI IKUO
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 1 Pages: 87-98
- DOI
  10.21873/anticanres.13083
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells2019
- Author(s)
  ITOH MAI、OKUHASHI YUKI、TAKAHASHI YUSUKE、SONODA YURI、MOHAMMAD SALWA、SAITO TATSUYA、SHIRATORI ERIKA、TOHDA SHUJI
- Journal Title
  
  Anticancer Research
  
  Volume: 39 Issue: 8 Pages: 4165-4170
- DOI
  10.21873/anticanres.13575
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] GLI1 and CTNNB1 Knockdown Activates NOTCH and mTOR Signalling in NB4 Myeloid Leukaemia Cells2018
- Author(s)
  OKUHASHI YUKI、ITOH MAI、TOHDA SHUJI
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 11 Pages: 6329-6332
- DOI
  10.21873/anticanres.12990
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] FOXP3 knockdown inhibits the proliferation and reduces NOTCH1 expression of T cell acute lymphoblastic leukemia cells2018
- Author(s)
  Yonekura Satoru、Itoh Mai、Shiratori Erika、Ohtaka Mika、Tohda Shuji
- Journal Title
  
  BMC Research Notes
  
  Volume: 11 Issue: 1 Pages: 582-582
- DOI
  10.1186/s13104-018-3700-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] NOTCH activation promotes glycosyltransferase expression in human myeloid leukemia cells2018
- Author(s)
  Wang Shichun、Itoh Mai、Shiratori Erika、Ohtaka Mika、Tohda Shuji
- Journal Title
  
  Hematology Reports
  
  Volume: 10 Issue: 3 Pages: 7576-7576
- DOI
  10.4081/hr.2018.7576
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] Effects of MERTK Inhibitors UNC569 and UNC1062 on the Growth of Acute Myeloid Leukaemia Cells2018
- Author(s)
  Koda Y, Itoh M, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 38 Issue: 1 Pages: 199-204
- DOI
  10.21873/anticanres.12208
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] BMI1 Inhibitors Down-regulate NOTCH Signaling and Suppress Proliferation of Acute Leukemia Cells2017
- Author(s)
  Ohtaka M, Itoh M, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Pages: 6047-6053
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] Hedgehog Stimulation Suppresses Clonogenicity and Activates NOTCH Signalling in T-lymphoblastic Leukaemia Jurkat Cells2017
- Author(s)
  Okuhashi Y, Itoh M, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Pages: 5005-5009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] 腫瘍マーカーとコンパニオン診断の適切利用による個別化医療の推進2017
- Author(s)
  東田修二
- Journal Title
  
  臨床病理
  
  Volume: 65 Pages: 314-316
- Data Source
  KAKENHI-PROJECT-26460669
[Journal Article] Detection of the MYD88 mutation by the combination of the allele-specific PCR and quenching probe methods2017
- Author(s)
  Nogami S, Kawaguchi-Ihara N, Shiratori E, Ohtaka M, Itoh M, Tohda S
- Journal Title
  
  International Journal of Laboratory Hematology
  
  Volume: 39 Issue: 2 Pages: 163-168
- DOI
  10.1111/ijlh.12598
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460669, KAKENHI-PROJECT-17K09005
[Journal Article] MYD88 Inhibitor ST2825 Suppresses the Growth of Lymphoma and Leukaemia Cells2017
- Author(s)
  Shiratori E, Itoh M, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 37 Pages: 6203-6209
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] 腫瘍マーカーとコンパニオン診断の適切利用による個別化医療の推進2017
- Author(s)
  東田修二
- Journal Title
  
  臨床病理
  
  Volume: 65 Pages: 314-316
- Data Source
  KAKENHI-PROJECT-17K09005
[Journal Article] Establishment of a quenching probe method for detection of NPM1 mutations in acute myeloid leukemia cells2016
- Author(s)
  Kawaguchi-Ihara N, Itoh M, Murohashi I, Tohda S
- Journal Title
  
  Oncology Letters
  
  Volume: 4 Pages: 2429-2432
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460669
[Journal Article] 造血器腫瘍のバイオマーカー：白血病幹細胞の個性診断をめざして2015
- Author(s)
  東田修二
- Journal Title
  
  臨床病理
  
  Volume: 63 Pages: 1110-1113
- Data Source
  KAKENHI-PROJECT-26460669
[Journal Article] NOTCH signaling roles in acute myeloid leukemia cell growth and interaction with other stemness-related signals2014
- Author(s)
  Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 34 Pages: 6259-6264
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26460669
[Journal Article] Effect of EPH-ephrin signaling on the growth of human leukemia cells2014
- Author(s)
  Takahashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 34 Pages: 2913-2918
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-26460669
[Journal Article] Effects of the HIF1 inhibitor, echinomycin, on growth and NOTCH signalling in leukaemia cells2013
- Author(s)
  Yonekura S, Itoh M, Okuhashi Y, Takahashi Y, Ono A, Nara N, Tohda S
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 3099-3103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Comparative effects of PP242 and rapamycin on mTOR signalling and NOTCH signalling in leukemia cells2013
- Author(s)
  Ono A, Oike R, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 33 Pages: 809-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] NOTCH Knockdown affects the proliferation and mTOR signaling of leukemia cells2013
- Author(s)
  Okuhashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 4293-4298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] NOTCH Knockdown affects the proliferation and mTOR signaling of leukemia cells2013
- Author(s)
  Okuhashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 33 Pages: 4293-4298
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Comparative effects of PP242 and rapamycin on mTOR signalling and NOTCH signalling in leukemia cells2013
- Author(s)
  Ono A, Oike R, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Res
  
  Volume: 33 Pages: 809-813
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] 微少残存白血病の検出法2013
- Author(s)
  東田修二
- Journal Title
  
  検査と技術
  
  Volume: 41 Pages: 19-24
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Effects of the HIF1 inhibitor, echinomycin, on growth and NOTCH signalling in leukaemia cells2013
- Author(s)
  Yonekura S, Itoh M, Okuhashi Y, Takahashi Y, Ono A, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 33 Pages: 3099-3103
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] リンパ系腫瘍：造血器腫瘍の新展開 WHO分類第４版2012
- Author(s)
  東田修二
- Journal Title
  
  臨床病理
  
  Volume: 60 Pages: 560-564
- NAID
  10030990548
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Effect of BMP4 on the growth and clonogenicity of human leukemia and lymphoma cells2012
- Author(s)
  Takahashi Y, Ishigaki T, Okuhashi Y, Ono A, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 32 Pages: 2813-2817
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] リンパ系腫瘍:造血器腫瘍の新展開WHO分類第4版2012
- Author(s)
  東田修二
- Journal Title
  
  臨床病理
  
  Volume: 60 Pages: 560-564
- NAID
  10030990548
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Advantages of the quenching probe method over otherPCR-based methods for detection of theJAK2 V617F mutation2012
- Author(s)
  Ono A, Okuhashi Y, Takahashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Oncology Lett
  
  Volume: 4 Issue: 2 Pages: 205-8
- DOI
  10.3892/ol.2012.741
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790523, KAKENHI-PROJECT-23590662
[Journal Article] Flow cytometric analysis of Notch1 and Jagged1 expression in normal blood cells and leukemia cells2012
- Author(s)
  Kanamori E, Itoh M, Tojo N, Koyama T, Nara N, Tohda S
- Journal Title
  
  Exp Ther Med
  
  Volume: 4 Issue: 3 Pages: 397-400
- DOI
  10.3892/etm.2012.633
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22790523, KAKENHI-PROJECT-23590662
[Journal Article] Effects of combination of notch inhibitor plus hedgehog inhibitor or Wnt inhibitor on growth of leukemia cells2011
- Author(s)
  Okuhashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 31 Pages: 893-896
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Promotion of the self-renewal capacity of human leukemia cells by sonic hedgehog protein2011
- Author(s)
  Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Murohashi I, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 31 Pages: 781-784
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23590662
[Journal Article] Promotionof the Self-renewal Capacity of Human Leukemia Cells by Sonic Hedgehog Protein.2011
- Author(s)
  Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Murohashi I, Nara N, Tohda S
- Journal Title
  
  Anticancer Res. 31
  
  Pages: 781-784
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Effects of Combination of Notch Inhibitor plus Hedgehog Inhibitor or Wnt Inhibitor on Growth of Leukemia Cells.2011
- Author(s)
  Okuhashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Res. 31
  
  Pages: 893-896
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Effects of gamma-secretase inhibitors on the growth of leukemia cells.2010
- Author(s)
  Okuhashi Y, Nara N, Tohda S
- Journal Title
  
  Anticancer Res. 30
  
  Pages: 495-498
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Gamma-secretase inhibitors induce erythroid differentiation in erythroid leukemia cell lines2010
- Author(s)
  Okuhashi Y, Itoh M, Arai A, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 4071-4074
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Amplification of IGH/CCND1 fusion gene in a primary plasma cell leukemia-case2010
- Author(s)
  Ishigaki T, Sasaki K, Kobayashi H, Tohda S
- Journal Title
  
  Cancer Genetics and Cytogenetics
  
  Volume: 201 Pages: 62-65
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] 白血病の分子標的治療のケミカルバイオロジー2010
- Author(s)
  東田修二
- Journal Title
  
  臨床化学 39
  
  Pages: 234-237
- NAID
  10025632530
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Gamma-secretase inhibitors induce erythroid differentiation in erythroid leukemia cell lines.2010
- Author(s)
  Okuhashi Y, Itoh M, Arai A, Nara N, Tohda S
- Journal Title
  
  Anticancer Res. 30
  
  Pages: 4071-4074
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Amplification of IGH/CCND1 fusion gene in a primary plasma cell leukemia case.2010
- Author(s)
  Ishigaki T, Sasaki K, Watanabe K, Nakamura N, Toyota S, Kobayashi H, Tohda S
- Journal Title
  
  Cancer Genet Cytogenet. 201
  
  Pages: 62-65
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Effects of gamma-secretase inhibitors on the growth of leukemia cells2010
- Author(s)
  Okuhashi Y, Nara N, Tohda S
- Journal Title
  
  Anticancer Research
  
  Volume: 30 Pages: 495-498
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] NF-kappaB activation induced by Notch ligand stimulation in acute myeloid leukemia cells2009
- Author(s)
  Itoh M, Fu L, Tohda S
- Journal Title
  
  Oncology Reports 22
  
  Pages: 631-634
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Transition of cleaved Notch1 and gene expression changes in myeloblastic leukemia cells stimulated with notch ligands.2009
- Author(s)
  Fu L, Katsube K, Tohda S
- Journal Title
  
  Anticancer Res. 29
  
  Pages: 3967-3970
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells.2009
- Author(s)
  Kawahara T, Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Res. 29
  
  Pages: 4629-4632
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] NF-kappaB activation induced by Notch ligandstimulation in acute myeloid leukemia cells.2009
- Author(s)
  Itoh M, Fu L, Tohda S
- Journal Title
  
  Oncol Rep. 22
  
  Pages: 631-634
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Cyclopamine and quercetin suppress the growth of leukemia and lymphoma cells2009
- Author(s)
  Kawahara T, Kawaguchi-Ihara N, Okuhashi Y, Itoh M, Nara N, Tohda S
- Journal Title
  
  Anticancer Research 29
  
  Pages: 4629-4632
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] 白血病の病態におけるNotchの機能解析2009
- Author(s)
  東田修二
- Journal Title
  
  臨床病理 57
  
  Pages: 351-356
- NAID
  10025224703
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Transition of cleaved Notch1 and gene expression changes in myeloblastic leukemia cells stimulated with notch ligands2009
- Author(s)
  Fu L, Katsube K, Tohda S
- Journal Title
  
  Anticancer Research 29
  
  Pages: 3967-3970
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] An autopsy case of multicentric Castleman's disease associated with interstitial nephritis and secondary AA amyloidosis2008
- Author(s)
  Morita-Hoshi Y, Tohda S, Miura O, Nara N
- Journal Title
  
  International Journal of Hematology 87
  
  Pages: 69-74
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Negative feedback regulation of colitogenie CD4+T cells byincreased granulopoiesis2008
- Author(s)
  Nemoto Y, Kanai T, Tohda s, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M
- Journal Title
  
  Inflammatory Bowel Diseases 14
  
  Pages: 1491-1503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Promotion of the self-renewal capacity of human acute leukemia cells by Wnt3A2008
- Author(s)
  Kawaguchi-Ihara N, Murohashi I, Nara N, Tohda S
- Journal Title
  
  Anticancer Research 28
  
  Pages: 2701-2704
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury.2008
- Author(s)
  Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, Kuwahara M, Tohda S, Sakano S, Sasaki S.
- Journal Title
  
  Kidney Int 73
  
  Pages: 1240-1250
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Expression and function of the Delta-1/Notch-2/Hes-1 pathway during experimental acute kidney injury2008
- Author(s)
  Kobayashi T, Terada Y, Kuwana H, Tanaka H, Okado T, KUwahara M, Tohda S, Sakano S, Sasaki S
- Journal Title
  
  Kidney International 73
  
  Pages: 1240-1250
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Promotion of the self-renewal capacity of human acute leukemia cells by Wnt3A.2008
- Author(s)
  Kawaguchi-Ihara N, Murohashi I, Nara N, Tohda S
- Journal Title
  
  Anticancer Res. 28
  
  Pages: 2701-2704
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Negative feedback regulation of colitogenic CD4+ T cells by increased granulopoiesis.2008
- Author(s)
  Nemoto Y, Kanai T, Tohda S, Totsuka T, Okamoto R, Tsuchiya K, Nakamura T, Sakamoto N, Fukuda T, Miura O, Yagita H, Watanabe M.
- Journal Title
  
  Inflamm Bowel Dis 14
  
  Pages: 1491-1503
- Data Source
  KAKENHI-PROJECT-20590557
[Journal Article] Involvement of Notch signaling in myelodysplastic syndrome2007
- Author(s)
  Fu L, Nara N, Tohda S
- Journal Title
  
  Leukemia Research 31
  
  Pages: 1168-1169
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Involvement of Notch signaling in myelodysplastic syndrome2007
- Author(s)
  Fu L, Nara N, Tohda S.
- Journal Title
  
  Leukemia Research 31
  
  Pages: 1168-1169
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells2007
- Author(s)
  Kogoshi H, Sato T, Koyama T Nara N, Tohda S
- Journal Title
  
  Oncology Reports 18
  
  Pages: 77-80
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Gamma-secretase inhibitors suppress the growth of Leukemia and lymphoma cells2007
- Author(s)
  Kogoshi H, Sato T, Koyama T Nara N, Tohda S
- Journal Title
  
  Oncology Reports 18
  
  Pages: 77-80
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Gamma-secretase inhibitors suppress the growth of leukemia and lymphoma cells2007
- Author(s)
  Kogoshi H, Sato T, Koyama T, Nara N, Tohda S.
- Journal Title
  
  Oncology Reports 18
  
  Pages: 77-80
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors2006
- Author(s)
  Tohda S, Sato T, Kogoshi H, Fu L, Sakano S, Nara N.
- Journal Title
  
  Leukemia Research 30
  
  Pages: 1385-1390
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] 白血病発症におけるNOTCH遺伝子異常-Notch阻害剤による治療の可能性2006
- Author(s)
  東田修二
- Journal Title
  
  医学のあゆみ 217
  
  Pages: 1093-1096
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Establishment of a novel B-cell lymphoma cell line with suppressed growth by gamma-secretase inhibitors2006
- Author(s)
  Tohda S, Sato T, Kogoshi H, Fu L, Sakano S, Nara N
- Journal Title
  
  Leukemia Research 30
  
  Pages: 1385-1390
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] 遺伝子検査の有用性 : 特に診断と治療効果判定2006
- Author(s)
  東田修二
- Journal Title
  
  日本検査血液学会雑誌 7
  
  Pages: 340-343
- NAID
  10018040260
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] NOTCH1 mutations are rare in acute myeloid leukemia2006
- Author(s)
  Fu L, Kogoshi H, Nara N, Tohda S.
- Journal Title
  
  Leukemia and Lymphoma 47
  
  Pages: 2400-2403
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] NOTCH1 mutations are rare in acute myeloid leukemia2006
- Author(s)
  Fu L, Kogoshi H, Nara N, Tohda S
- Journal Title
  
  Leukemia and Lymphoma 47
  
  Pages: 2400-2403
- Description
  「研究成果報告書概要(和文)」より
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18590522
[Journal Article] Effect of Notch ligands on in vitro sensitivity to chemotherapeutic drugs in leukemia and lymphoma cells.2005
- Author(s)
  Kogoshi H, Tohda S, Fu L, Koyama T, Nara N
- Journal Title
  
  Oncology Reports 14
  
  Pages: 723-726
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] The Notch ligand, Delta-1, alters retinoic acid-induced neutrophilic differentiation into monocytic and reduced RA-induced apoptosis in NB4 cells2005
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N
- Journal Title
  
  Leukemia Research 29
  
  Pages: 197-203
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells.2005
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N.
- Journal Title
  
  Leukemia Research 29
  
  Pages: 197-203
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Effect of Notch ligands on in vitro sensitivity to chemotherapeutic drugs in leukemia and lymphoma cells.2005
- Author(s)
  Kogoshi H, Tohda S, Fu L, Nara N.
- Journal Title
  
  Oncology Reports 14
  
  Pages: 723-726
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells.2005
- Author(s)
  Tohda S, Kogoshi H, Murakami N, Sakano S, Nara N
- Journal Title
  
  Experimental Hematology 33
  
  Pages: 558-563
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] The Notch ligand, Delta-1, alters retinoic acid-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells2005
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N
- Journal Title
  
  Leukemia Research 29
  
  Pages: 197-203
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduces RA-induced apoptosis in NB4 cells.2005
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N
- Journal Title
  
  Leukemia Research 29
  
  Pages: 197-203
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] Effect of Notch ligands on in vitro sensitivity to chemotherapeutic drugs in leukemia and lymphoma cells2005
- Author(s)
  Kogoshi H, Tohda S, Fu L, Nara N
- Journal Title
  
  Oncology Reports 14
  
  Pages: 723-726
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Diverse Effects of the Notch Ligands Jagged1 and Delta1 on the Growth and Differentiation of Primary Acute Myeloblastic Leukemia Cells2005
- Author(s)
  Tohda S, Kogoshi H, Sakano S, Nara N
- Journal Title
  
  Experimental Hematology 33
  
  Pages: 558-563
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] The Notch ligand, Delta-1, alters retinoic acid (RA)-induced neutrophilic differentiation into monocytic and reduced RA-induced apoptosis in NB4 cells.2005
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Sakano S, Nara N
- Journal Title
  
  Leukemia Research 29
  
  Pages: 197-203
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells.2005
- Author(s)
  Tohda S, Kogoshi H, Murakami N, Sakano S, Nara N.
- Journal Title
  
  Experimental Hematology 33
  
  Pages: 558-563
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Nara N
- Journal Title
  
  International Journal of Molecular Medicine Vol 14
  
  Pages: 223-226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] The Notch ligand, Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Sakano S, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 13
  
  Pages: 419-423
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] The Notch ligand, Delta-1, reduces TNF-α-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 861-866
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] The Notch ligand, Delta-1, reduces TNF-α-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cell2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N
- Journal Title
  
  International Journal of Molecular Medicine Vol 14
  
  Pages: 861-866
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] The Notch ligand, Delta-1, reduces TNF-α-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 4
  
  Pages: 861-866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] The Notch ligand, Delta-1, reduces TNF-a-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 861-866
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Sakano S, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 13
  
  Pages: 419-423
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloblastic leukemia cell lines2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 223-226
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 223-226
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloblastic leukemia cell lines.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Nara N.
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 223-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] The Notch ligand, Delta-1, reduces TNF-α-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, KogoshiH, Nara N
- Journal Title
  
  International Journal of Molecular Medicine Vol 14
  
  Pages: 861-866
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] TNF-α-induced growth suppression and apoptosis by decreasing activation of caspases in U937 cells.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Kogoshi H, Nara N.
- Journal Title
  
  International Journal of molecular Medicine 14
  
  Pages: 861-866
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Notch ligands, Delta-1, partially inhibits GM-CSF-induced differentiation and apoptosis along with reducing the cleavage of PARP in U937 cells.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Sakano S, Nara N.
- Journal Title
  
  International Journal of Molecular Medicine 13
  
  Pages: 419-423
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590446
[Journal Article] Cellular analysis of growth suppression induced by the Notch ligands, Delta-1 and Jagged-1 in two myeloid leukemia cell lines.2004
- Author(s)
  Murata-Ohsawa M, Tohda S, Nara N
- Journal Title
  
  International Journal of Molecular Medicine 14
  
  Pages: 223-226
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-16590448
[Journal Article] Diverse Effects of the Notch Ligands Jagged1 and Delta1 on the Growth and Differentiation of Primary Acute Myeloblastic Leukemia Cells
- Author(s)
  Tohda S, Kogoshi H, Sakano S, Nara N
- Journal Title
  
  Experimental Hematology (in press)
- Data Source
  KAKENHI-PROJECT-16590446
[Presentation] NOTCH阻害剤IMR-1AのTリンパ芽球性白血病細胞の増殖に対する効果2022
- Author(s)
  伊藤千紗、東田修二、伊藤真以
- Organizer
  第69回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07780
[Presentation] c-MYC阻害剤の白血病細胞の増殖に対する効果2022
- Author(s)
  野口琴未、東田修二、伊藤真以
- Organizer
  第69回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07780
[Presentation] 白血病細胞の増殖におけるレニン・アンジオテンシン系の作用と治療への応用2022
- Author(s)
  伊藤真以、東田修二
- Organizer
  第69回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07780
[Presentation] NOTCH阻害剤SAHM1のTリンパ球性白血病細の増殖に対する効果2021
- Author(s)
  伊藤千紗, 伊藤真以, 東田修二
- Organizer
  第68 回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07780
[Presentation] HOXA9阻害剤による白血病細胞株の増殖抑制作用2020
- Author(s)
  薗田由莉、伊藤真以、東田修二
- Organizer
  第67回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-20K07780
[Presentation] Metformin inhibits the growth of myeloid leukemia cells partly due to suppression of tyro3 expression2019
- Author(s)
  Tatsuya Saito, Mai Itoh, Shuji Tohda
- Organizer
  24th Congress of European Hematology Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] FLT3-ITD Enhances Proliferation and Survival of AML Cells through Activation of RSK1 to Upregulate the mTORC1/eIF4F Pathway Cooperatively with PIM or PI3K and to Inhibit Bad and Bim2019
- Author(s)
  Ayako Nogami, Watanabe Daisuke, Keigo Okada, Hiroki Akiyama, Yoshihiro Umezawa, Toshikage Nagao, Shuji Tohdaand Osamu Miura
- Organizer
  60th ASH Annual Meeting and Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] TIM-3蛋白のバーキットリンパ腫細胞株の増殖における意義の検討2018
- Author(s)
  白鳥恵理香、大高美香、伊藤真以、東田修二
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] 種々の白血病細胞の増殖に対するBrequinar sodiumの作用2018
- Author(s)
  大高美香、伊藤真以、東田修二
- Organizer
  第65回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] siRNAとCRISPER/Cas9システムを用いたゲノム編集による白血病細胞の増殖への効果2017
- Author(s)
  奥橋佑基、細萓茂実、東田修二
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] BMI1 inhibitors suppress cell growth and NOTCH signalling of acute leukemia cells2017
- Author(s)
  Mika Ohtaka, Mai Itoh, and Shuji Tohda
- Organizer
  46th Annual Scientific Meeting of the International Society for Experimental Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] MERチロシンキナーゼ阻害による白血病細胞の増殖抑制2017
- Author(s)
  甲田祐樹、大高美香、白鳥恵理香、伊藤真以、東田修二
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] リンパ系腫瘍細胞に対するMYD88阻害薬の細胞分子生物学的作用2017
- Author(s)
  白鳥恵理香、大高美香、伊藤真以、東田修二
- Organizer
  第64回日本臨床検査医学会学術集会
- Data Source
  KAKENHI-PROJECT-17K09005
[Presentation] 白血病細胞の増殖に対するMERチロシンキナーゼの阻害剤の作用2016
- Author(s)
  甲田祐樹、大高美香、白鳥恵理香、伊藤真以、東田修二
- Organizer
  第63回日本臨床検査医学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2016-09-02
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] Highly Sensitive Detection of MYD88 Mutation by Combination of Allele-specific PCR and Quenching Probe Method2016
- Author(s)
  Shohei Nogami, Mai Itoh, and Shuji Tohda
- Organizer
  The 14th Asian Society for Clinical Pathology and Laboratory Medicine Congress
- Place of Presentation
  National Taiwan University (Taipei, Taiwan)
- Year and Date
  2016-03-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 急性Tリンパ芽球性白血病におけるPTENの機能解析2016
- Author(s)
  奥橋佑基、細萓茂実、東田修二
- Organizer
  第63回日本臨床検査医学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2016-09-04
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 白血病細胞でのNOTCHシグナル活性化に伴うmicroRNA発現の変化2016
- Author(s)
  野上祥平、白鳥恵理香、大高美香、伊藤真以、東田修二
- Organizer
  第63回日本臨床検査医学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2016-09-04
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] Mechanisms of suppressive effects of MYD88 Inhibitors on the Growth of Lymphoma and Leukemia Cells2016
- Author(s)
  Erika Shiratori, Mai Itoh, Mika Ohtaka, Shohei Nogami, Shuji Tohda
- Organizer
  The 58th American Society of Hematology
- Place of Presentation
  San Diego (USA)
- Year and Date
  2016-12-04
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] BMI1 阻害剤による白血病細胞のアポトーシス誘導を介した増殖抑制作用2016
- Author(s)
  大高美香、野上祥平、白鳥恵理香、伊藤真以、東田修二
- Organizer
  第63回日本臨床検査医学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2016-09-04
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 腫瘍マーカーとコンパニオン診断の適切利用による個別化医療の推進2016
- Author(s)
  東田修二
- Organizer
  第63回日本臨床検査医学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2016-09-03
- Invited
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] MYD88の阻害によるリンパ腫細胞の増殖抑制作用2016
- Author(s)
  白鳥恵理香、野上祥平、大高美香、伊藤真以、東田修二
- Organizer
  第63回日本臨床検査医学会
- Place of Presentation
  神戸国際会議場（神戸市）
- Year and Date
  2016-09-04
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 白血病細胞における糖転移酵素の発現とNotchシグナル活性化との関連2015
- Author(s)
  王詩淳、野上祥平、白鳥恵理香、大高美香、伊藤真以、東田修二
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜市）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 白血病細胞に対するBMI阻害剤の細胞分子生物学的作用2015
- Author(s)
  大高美香、白鳥恵理香、王詩淳、野上祥平、伊藤真以、東田修二
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜市）
- Year and Date
  2015-11-20
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] リンパ腫・白血病細胞株の増殖に対するMYD88阻害薬とBTK阻害薬の作用2015
- Author(s)
  白鳥恵理香、野上祥平、王詩淳、大高美香、伊藤真以、東田修二
- Organizer
  第62回日本臨床検査医学会学術集会
- Place of Presentation
  長良川国際会議場（岐阜市）
- Year and Date
  2015-11-21
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 白血病細胞の増殖に対するBmi1阻害剤の作用2014
- Author(s)
  大高美香、高橋祐介、白鳥恵理香、伊藤真以、東田修二
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-11-24
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] BCR-ABL融合遺伝子の定量RT-PCR法と定性RT-Nested PCR法での検出感度の比較2014
- Author(s)
  白鳥恵理香、大高美香、高橋祐介、伊藤真以、東田修二
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-11-24
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] 造血器腫瘍のバイオマーカー：白血病幹細胞の個性診断をめざして. シンポジウム　癌生物学とバイオマーカー探索2014
- Author(s)
  東田修二
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-11-25
- Invited
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] Quenching probe法を用いたNPM1遺伝子変異の検出法2014
- Author(s)
  川口寛子、伊藤真以、室橋郁生、東田修二
- Organizer
  第61回日本臨床検査医学会学術集会
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-11-24
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] Effects of GLI1 and CTNNB1 knockdown on NOTCH signaling of leukemia cells2014
- Author(s)
  Yuki Okuhashi, Yusuke Takahashi, Mika Ohtaka, Erika Shiratori, Shijun O, Mai Itoh, Shuji Tohda
- Organizer
  The 56th American Society of Hematology
- Place of Presentation
  サンフランシスコ（アメリカ）
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-26460669
[Presentation] Effects of NOTCH knockdown on the proliferation and mTOR signaling of mTOR signaling of T-ALL and AML cell lines2013
- Author(s)
  Yuki Okuhashi, Mai Itoh, Nobuo Nara, Shuji Tohda
- Organizer
  The 55^<th> American Society of Hematology
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2013-12-07
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] Effects of hypoxia on HIF, Notch, Akt, and NF-kB signaling in leukemia cell lines2013
- Author(s)
  Mai Itoh, Yusuke Takahashi, Yuki Okuhashi, Shuji Tohda
- Organizer
  The 55^<th> American Society of Hematology
- Place of Presentation
  New Orleans, LA, USA
- Year and Date
  2013-12-09
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 白血病細胞におけるEph/ephrin系とNotch系との相互作用2013
- Author(s)
  高橋祐介, 奥橋佑基, 伊藤真以, 東田修二
- Organizer
  第60回日本臨床検査医学会学術集会
- Place of Presentation
  神戸
- Year and Date
  2013-11-03
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 骨髄微小環境を再現した低酸素培養が白血病細胞に及ぼす影響2012
- Author(s)
  伊藤真以, 奥橋佑基, 高橋祐介, 大野彩, 東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 白血病細胞におけるNotchシグナルのmTORシグナルへの作用2012
- Author(s)
  奥橋佑基, 大野彩, 高橋祐介, 伊藤真以, 東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] シンポジウム「血液疾患遺伝子解析の読み方のポイント」:悪性リンパ腫の診断に必要な遺伝子解析と結果の読み方2012
- Author(s)
  東田修二
- Organizer
  第13回日本検査血液学会学術集会
- Place of Presentation
  高槻
- Year and Date
  2012-07-29
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 白血病細胞の増殖に対するmTOR阻害剤の作用2012
- Author(s)
  大野彩, 奥橋佑基, 高橋祐介, 伊藤真以, 東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] チロシンキナーゼ阻害薬投与中の慢性骨髄性白血病患者における微少残存病変検出の3種の遺伝子検査法の比較2012
- Author(s)
  東田修二, 大野彩, 高橋祐介, 奥橋佑基, 伊藤真以
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] Eph/ephrinの白血病細胞の増殖に対する作用2012
- Author(s)
  高橋祐介, 奥橋佑基, 大野彩, 伊藤真以, 東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Year and Date
  2012-12-02
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] BMP4の白血病細胞の増殖に対する作用2011
- Author(s)
  高橋祐介, 石垣知寛, 奥橋佑基, 大野彩, 伊藤真以, 東田修二
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 白血病細胞の増殖におけるHedgehogシグナルとNotchシグナルの相互作用2011
- Author(s)
  奥橋佑基, 大野彩, 高橋祐介, 伊藤真以, 東田修二
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2011-11-19
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 骨髄増殖性腫瘍におけるJAK2V617F変異の種々の検出法の比較2011
- Author(s)
  大野彩, 高橋祐介, 奥橋佑基, 伊藤真以, 東田修二
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山
- Year and Date
  2011-11-20
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] レナリドミド著効例を含む5q-症候群の3例2011
- Author(s)
  東田修二, 奈良信雄
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Year and Date
  2011-10-14
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 白血病細胞の増殖におけるNotchシグナルとWnt, Hedgehogシグナルとの相互作用2010
- Author(s)
  奥橋佑基, 石垣知寛, 伊藤真以, 東田修二
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  東京
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] 白血病細胞の増殖におけるNotchシグナルとWnt, Hedgehogシグナルとの相互作用2010
- Author(s)
  奥橋佑基, 石垣知寛, 伊藤真以, 東田修二
- Organizer
  第57回日本臨床検査医学会学術集会
- Place of Presentation
  京王プラザホテル(東京都)
- Year and Date
  2010-09-10
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] 白血病の分子標的治療のケミカルバイオロジー2009
- Author(s)
  東田修二
- Organizer
  第49回日本臨床化学会学術集会ワークショップ
- Place of Presentation
  長崎
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] 白血病の分子標的治療のケミカルバイオロジー2009
- Author(s)
  東田修二
- Organizer
  第49回日本臨床化学会学術集会
- Place of Presentation
  長崎大学医学部
- Year and Date
  2009-09-18
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] Notchシグナル阻害剤による赤白血病細胞の赤芽球分化誘導効果2009
- Author(s)
  奥橋佑基、河原達雄、井原寛子、星百合子、東田修二
- Organizer
  第56回日本臨床検査医学会総会
- Place of Presentation
  札幌
- Year and Date
  2009-08-28
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] 白血病の病態におけるNotchの機能解析2008
- Author(s)
  東田修二
- Organizer
  第55回日本臨床検査医学会総会
- Place of Presentation
  名古屋国際会議場
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] 日本臨床検査医学会学会賞生命科学賞受賞、受賞講演.白血病の病態におけるNotchの機能解析2008
- Author(s)
  東田修二
- Organizer
  第55回日本臨床検査医学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-11-28
- Data Source
  KAKENHI-PROJECT-20590557
[Presentation] Notchシグナル阻害剤による白血病・リンパ腫細胞の増殖抑制2007
- Author(s)
  東田修二、小越英恵、付王路、星百合子
- Organizer
  第54回日本臨床検査医学会総会
- Place of Presentation
  大阪
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(和文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Presentation] Growth inhibition of leukemia and lymphoma cells by Notch signalling inhibitors2007
- Author(s)
  Tohda S, Kogoshi H, Fu L, Hoshi Y.
- Organizer
  54th meeting of Japanese Society of Laboratory Medicine
- Place of Presentation
  Osaka
- Year and Date
  2007-11-24
- Description
  「研究成果報告書概要(欧文)」より
- Data Source
  KAKENHI-PROJECT-18590522
[Presentation] Effects of hypoxia on HIF, Notch, Akt, and NF-κB signaling in leukemia cell lines
- Author(s)
  Mai Itoh, Yusuke Takahashi, Yuki Okuhashi, Shuji Tohda
- Organizer
  The 55th American Society of Hematology
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 白血病細胞におけるNotchシグナルのmTORシグナルへの作用
- Author(s)
  奥橋佑基、大野彩、高橋祐介、伊藤真以、東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] レナリドミド著効例を含む5q-症候群の３例
- Author(s)
  東田修二, 奈良信雄
- Organizer
  第73回日本血液学会学術集会
- Place of Presentation
  名古屋
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 骨髄微小環境を再現した低酸素培養が白血病細胞に及ぼす影響
- Author(s)
  伊藤真以、奥橋佑基、高橋祐介、大野彩、東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] 悪性リンパ腫の診断に必要な遺伝子解析と結果の読み方
- Author(s)
  東田修二
- Organizer
  第13回日本検査血液学会学術集会・シンポジウム
- Place of Presentation
  高槻
- Invited
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] Effects of NOTCH knockdown on the proliferation and mTOR signaling of mTOR signaling of T-ALL and AML cell lines
- Author(s)
  Yuki Okuhashi, Mai Itoh, Nobuo Nara, Shuji Tohda
- Organizer
  The 55th American Society of Hematology
- Place of Presentation
  New Orleans, LA, USA
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] フローサイトメトリーによる正常血球および白血病細胞におけるNotch1蛋白の解析
- Author(s)
  金盛英里子、小山高敏、奈良信雄、東田修二、東條尚子
- Organizer
  第12回日本検査血液学会学術集会
- Place of Presentation
  倉敷
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] BMP4の白血病細胞の増殖に対する作用
- Author(s)
  高橋祐介、石垣知寛、奥橋佑基、大野彩、伊藤真以、東田修二
- Organizer
  第58回日本臨床検査医学会学術集会
- Place of Presentation
  岡山
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] チロシンキナーゼ阻害薬投与中の慢性骨髄性白血病患者における微少残存病変検出の３種の遺伝子検査法の比較
- Author(s)
  東田修二、大野彩、高橋祐介、奥橋佑基、伊藤真以
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590662
[Presentation] Eph/ephrinの白血病細胞の増殖に対する作用
- Author(s)
  高橋祐介、奥橋佑基、大野彩、伊藤真以、東田修二
- Organizer
  第59回日本臨床検査医学会学術集会
- Place of Presentation
  京都
- Data Source
  KAKENHI-PROJECT-23590662

1. NARA Nobuo (00142258)

# of Collaborated Projects: 6 results

# of Collaborated Products: 9 results
2. MURAKAMI Naomi (50143582)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. 黒川浩 (50242201)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 広沢信作 (50143574)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鈴木謙 (90251511)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 三木徹 (90242180)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. OHTAKA Mika

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
8. SHIRATORI Erika

# of Collaborated Projects: 1 results

# of Collaborated Products: 12 results
9. 大澤真以

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

TOHDA Shuji 東田 修二

東田 修二 トウダ シュウジ

Research Projects

Research Products

Co-Researchers

Development of molecular targeted drug sensitivity tests that integrate gene panel testing and signaling protein analysis for leukemiaPrincipal Investigator

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Companion Diagnostics to predict the effects of molecularly-targeted drugs on acute leukemia stem cellsPrincipal Investigator

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Tests for self-renewal signals of acute leukemia stem cells and prediction of the effects of molecular-targeted drugs for the signalsPrincipal Investigator

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Tests for quantity and characteristics of acute leukemia stem cells to search molecular-targeted therapies suitable for each casePrincipal Investigator

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Role of Notch in the pathophysiology of leukemia stem cells and drug sensitivity tests for Notch inhibitorsPrincipal Investigator

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A novel therapy targeting Notch molecule against leukemia and a method to select patients suitable for the therapyPrincipal Investigator

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The method to surmise the prognosis of leukemia patients by analyzing the function of Notch proteinPrincipal Investigator

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Study on the System Detecting the Effect of the Molecular-Targeting Therapy for Leukemia and the Patients Prognosis.

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Study on the System Detecting the residual Leukeinic Cells after the Gene-targeted Therapy forLeukemia

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Development of the method to surmise the prognosis of acute myeloblastic leukemia patients by analyzing the expression of Notch proteinPrincipal Investigator

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The establishment of the system that predicts the prognosis of acute leukemia patients on the basis of the biological properties of leukemic blast progenitors.

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Development of the method to infer the responsiveness of acute myeloblastic leukemia cells for G-CSFPrincipal Investigator

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The establishment of the method which detects the minimal residual leukemic cells in acute myelogenous patients in remisson and predicts the patients prognosis.

Principal Investigator

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TOHDA Shuji 東田修二

東田修二トウダシュウジ

[Book] 標準臨床検査医学第5版　（分担）第10章　染色体検査・遺伝子検査2023

[Book] 日常診療のための検査値のみかた　-　造血器腫瘍関連染色体・遺伝子検査2015

[Book] 急性白血病、血友病など17項目(福井次矢、奈良信雄編)(内科診断学第2版)2008