MANDAI Michiko 万代道子

… Alternative Names

万代道子マンダイミチコ

MANDEI Michiko 万代道子

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Researcher Number	80263086
External Links
Affiliation (Current)	2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 客員研究員
Affiliation (based on the past Project Information) *help	2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 客員研究員 2019 – 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 副プロジェクトリーダー 2015 – 2017: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 副プロジェクトリーダー 2014: 独立行政法人理化学研究所, 多細胞システム形成研究センター, 副プロジェクトリーダー 2013: 独立行政法人理化学研究所, 発生・再生科学総合研究センター, 副プロジェクトリーダー … More 2012: 独立行政法人理化学研究所, 網膜再生医療研究開発プロジェクト, 副プロジェクトリーダー 2006 – 2011: RIKEN, Laboratory for Retinal Regeneration, Researcher, 網膜再生医療研究チーム, 研究員 2004 – 2005: 京都大学, 医学研究科, 助手 2001: 京大, 医学(系)研究科(研究院), 助手 1997 – 2000: 京都大学, 医学研究科, 助手 1999: 京都大学, 大学院・医学研究科, 助手 1995: Kyoto Univ., Graduate School of Medicine Instructor, 医学研究科, 助手 Less
Review Section/Research Field	Principal Investigator Ophthalmology / Ophthalmology / Basic Section 56060:Ophthalmology-related Except Principal Investigator Ophthalmology / Ophthalmology / Basic Section 56060:Ophthalmology-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
Keywords	Principal Investigator 網膜変性 / 視細胞移植 / 網膜組織移植 / エンドトキシンぶどう膜炎 / 眼科学 / 再生医学 / 網膜移植 / LPS / VEGF / 17 beta estradiol … More / シナプス形成 / ES/iPS細胞 / リポポリサッカライト / 一酸化窒素合成酵素 / レクチン / Nrl / 移植環境 / グリオーシス / 移植治療 / ES細胞 / 立体分化培養 / 網膜シート移植 / 組織移植 / エンドトキシンブドウ膜炎 / 細胞浸潤 / E-セレクチン / P-セレクチン / エストロゲン / 遺伝子発現 / 血管内皮 / タモキシフェン / モノクローナル抗体 / cellular infiltration / endotoxin-induced uveitis / E-selectin / P-selectin / estrpgen / gene expression / vaxcular endothelium / 17beta estradiol / VEGFR2 / 血管内皮細胞 / 脈絡膜血管新生(CNV) / 未熟児網膜症 / 17beta-estradiol / ぶどう膜炎 / 増殖 / choroidal neovascularization (CNV) / vascular endothelial cell / VEGFR-2 / retinopty of prematurity (ROP) / 網膜色素変性 / 遺伝子診断 / 抗リカバリン抗体 / 網膜自発蛍光 / 自己免疫網膜症 / 網膜光干渉断層像 / 色 / retinitis pigmentosa / genetic diagnosis / anti-recoverin antibody / autoimmune retinopathy / retinal autofluorescence / ES/iPS由来網膜 / 移植 / 遺伝改変 / iPS細胞 / シナプス定量 / 遺伝改変株 / 自己組織化網膜 / 生着 / シナプスマーカー / ES/iPS細胞由来網膜 / 多電極アレイ / CLEM / 視機能回復 / 網膜再生 / 視細胞シナプス / 水平細胞 … More Except Principal Investigator 網膜色素上皮 / 周皮細胞 / 内皮細胞 / PDGF受容体 / アポトーシス / bax遺伝子 / bcl-2遺伝子 / NMDA受容体 / グルタミン酸 / 虚血性網膜細胞死 / DNAの断片化 / delayed neruonal death / Apoptosis / DNA fragmentation / Bax / Bcl-2 / Glutamate / Nitric oxide / 再生医療 / in situ hybridization / 神経網膜 / 発生 / 変性プライマー / RCSラット / サブトラクション / 網膜血管新生 / vascular-remodeling / Ang1 / PDGFR-α抗体 / PDGFR-β抗体 / 血管発生 / 血小板由来増殖因子 / 血管内皮細胞 / 血管壁細胞 / 血管リモデリング / エンドトキシンぶどう膜炎 / サイトカイン / TGF-β / 一酸化窒素合成酵素 / 色素上皮 / 角膜上皮 / エンドセリン / エンドトキシぶどう膜炎 / 新生血管 / 自己免疫性ブドウ膜炎 / PCR / ぶどう膜炎 / 虹彩毛様体 / Endotoxin-indwed uveitis / cytokine / TGF-beta / Nitric Oxid / Endothelin / retinal pyment epithelium / corneal epithelium / 虚血性網膜神経細胞死 / TUNEL陽性(DNA断片化)細胞 / 一酸化窒素 / TUNE陽性(DNA断片化)細胞 / bal-2遺伝子 / 虚血網膜 / 遅発性神経細胞死 / N-メチル-D-アスパラギン酸(NMDA) / TUNEL positive cell / 増殖性硝子体網膜症 / E2F転写因子 / NF_KB転写因子 / 遺伝子導入 / NFkBデコイ / 網膜芽細胞腫 / 変異型Rb遺伝子導入 / 遺伝子治療 / NFkB転写因子 / PVR / NF_<kappa>B / E2F / gene transfer / 虚血性神経細胞死 / 一酸化炭素(NO) / 一酸化窒素(NO) / TUNEL染色 / N-methyl-D-aspartate(NMDA) / 温度感受性リポソーム / 薬物送達 / 脈絡膜新生血管 / 加齢黄斑変性症 / 光化学療法 / 光線力学療法 / 加齢黄班変性症 / レーザー / thermo-sensitive liposone / dny delivery / choroidal recvasalarization / age-related macular degeieration / photodynamic therapy / slit lamp / 白血球 / 網膜 / 糖尿病 / leukocyte / retina / diabetes / アンジオポイエチン2 / AT1受容体 / 糖尿病網膜症 / 網膜浮腫 / 眼内血管増殖疾患 / 内皮-周皮細胞間制御機構 / pericyte loss / アンジオテンシン / ATI阻害薬 / アンジオポエチン1 / ストレプトゾトシン糖尿病ラット / アンジオポイエチン1 / Tie2 / VEGFファミリー / アンジオポイエチン / アンジオランシン / VEGF / 血管増殖 / 透過性 / endothelial cells / pericytes / angiopoietin 2 / AT 1 receptor / angiotensin / diabetic retinopathy / retinal edema / PDGF-receptor / 視細胞 / トランスジェニックマウス / 網膜移植 / in situ hybridzation / photoreceptor / regenerative medicine / transgenic mice / retinal transplantation / 網膜色素変性 / iPS細胞 / 薬物治療 / 網膜色素変性症 / 組織保存 / 能動的低代謝 / 冬眠 / 休眠 / オルガノイド / 日内休眠 / 組織保存法 / 網膜シート / 低温耐性 / 低代謝耐性 Less

ES/iPS細胞由来網膜移植の機能的生着向上のためのホスト網膜環境に関する研究Principal Investigator
- Principal Investigator
  
  万代道子
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Institute of Physical and Chemical Research
ES/iPS由来網膜組織を用いた実用的な視機能再建のための次世代治療の開発Principal Investigator
- Principal Investigator
  
  万代道子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Institute of Physical and Chemical Research
網膜色素変性に対するリードスルー薬の開発
- Principal Investigator
  
  前田亜希子
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Institute of Physical and Chemical Research
Development of a novel tissue preservation method via mammalian hypometabolism
- Principal Investigator
  
  高橋政代
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  Ritsumeikan University
  Institute of Physical and Chemical Research
Development of new types of ES/iPS-retina for better synaptic integrationPrincipal Investigator
- Principal Investigator
  
  Mandai Michiko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Institute of Physical and Chemical Research
Evaluaton of ES/iPS-retinal sheettransplantation in reference to retinal cell transplantation in mouse retnal degeneration modelPrincipal Investigator
- Principal Investigator
  
  MANDAI Michiko
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  The Institute of Physical and Chemical Research
Modulation of host environment in retinal cell transplantation using retinal degeneration models.Principal Investigator
- Principal Investigator
  
  MANDAI Michiko
- Project Period (FY)
  2009 – 2011
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  The Institute of Physical and Chemical Research
Detailed studies on the conditions of ES derived photoreceptor precursors and the host retinal environment for the successful transplantationPrincipal Investigator
- Principal Investigator
  
  MANDAI Michiko
- Project Period (FY)
  2007 – 2008
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  The Institute of Physical and Chemical Research
Multi-analytic approach to the understanding of the patho-physiology of retinitis pigmentosa and related diseases using genetic, immunologic and clinical imaging methodsPrincipal Investigator
- Principal Investigator
  
  MANDAI Michiko
- Project Period (FY)
  2005 – 2006
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  RIKEN
  Kyoto University
Transplantation of enriched photoreceptor precursor cells into degenerated retina and conditioning of host retina.
- Principal Investigator
  
  AKIMOTO Masayuki
- Project Period (FY)
  2004 – 2005
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
眼内新生血管における性差とその病態機序及び治療におけるエストロゲンの役割Principal Investigator
- Principal Investigator
  
  万代道子
- Project Period (FY)
  2001
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
増殖因子制御による血管発生の時間的・空間的解析
- Principal Investigator
  
  TAKAGI Hitoshi (高木均)
- Project Period (FY)
  2000 – 2001
- Research Category
  
  Grant-in-Aid for Exploratory Research
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
The pathological investigation of proliferative diabetic retinopathy based on the control of retinal pericytes
- Principal Investigator
  
  TAKAGI Hitoshi
- Project Period (FY)
  2000 – 2002
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
Photodynamic Therapy and dry delivery system for choroidal recvasalarization
- Principal Investigator
  
  NISHIWAKI Hirokazu
- Project Period (FY)
  1999 – 2001
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
The role of leukocyte in the pathogeuesis of diabctic retiuoparthy
- Principal Investigator
  
  KIRYU Junichi
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
The role of estrogen for the etiology and treatment of intraocular inflammation and neovascularizationPrincipal Investigator
- Principal Investigator
  
  MANDAI Michiko
- Project Period (FY)
  1999 – 2000
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
The elucidation of molecular mechanism in delayed neruonal death and its control in rat retina
- Principal Investigator
  
  HONDA Yoshihito
- Project Period (FY)
  1998 – 1999
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
Key Molecules involved in the Early Phase of Anterior UveitisPrincipal Investigator
- Principal Investigator
  
  MANDAI Michiko
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
The study of apoptosis and contributions of Bcl-2 family genes in delayed neruonal death after retinal ischemia
- Principal Investigator
  
  KASHII Satoshi
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
Inhibition of proliferative vitreo retinopathy by controling the related transcription factors.
- Principal Investigator
  
  TAKAHASHI Masayo
- Project Period (FY)
  1997 – 1998
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY
細胞接着機構が神経網膜の誕生と再生に果たす役割の解明
- Principal Investigator
  
  吉村長久
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
ぶどう膜炎における血液-房水関門の破綻と一酸化窒素合成酵素の関与についてPrincipal Investigator
- Principal Investigator
  
  万代道子
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
網膜色素上皮細胞における貧食能特異受容体のクローニング
- Principal Investigator
  
  栗山晶治
- Project Period (FY)
  1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kyoto University
Cytokine expression in ocular tissne and theirde in the pathegenesis of Uveitis
- Principal Investigator
  
  KASHII Satoshi
- Project Period (FY)
  1993 – 1995
- Research Category
  
  Grant-in-Aid for General Scientific Research (B)
- Research Field
  
  Ophthalmology
- Research Institution
  KYOTO UNIVERSITY

[Book] 医学のあゆみ「末期変性網膜に対するES/iPS細胞由来網膜シート移植」2015
- Author(s)
  万代　道子
- Total Pages
  5
- Publisher
  医歯薬出版
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 実験医学増刊号「再生医療２０１５」2015
- Author(s)
  万代　道子
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 日本の眼科「網膜再生治療の現在と未来」2015
- Author(s)
  万代　道子
- Total Pages
  4
- Publisher
  日本眼科医会
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 実験医学「末期網膜変性モデルに対するES/iPS細胞由来網膜シート移植による再生治療」2015
- Author(s)
  万代　道子
- Total Pages
  5
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 再生医療用語ハンドブック「網膜再生　羊膜」2015
- Author(s)
  万代　道子
- Total Pages
  2
- Publisher
  メディカルトリビューン
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 再生医療技術の最前線「網膜の再生医療」2013
- Author(s)
  万代　道子
- Total Pages
  8
- Publisher
  ジーエムシー出版
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 臨床眼科「ES細胞、iPS細胞による網膜の再生」2013
- Author(s)
  万代　道子
- Total Pages
  5
- Publisher
  医学書院
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 再生医療　上皮感覚器「神経網膜の再生」2013
- Author(s)
  万代　道子
- Total Pages
  7
- Publisher
  朝倉書店
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 日本医師会雑誌「網膜の再生医療」2013
- Author(s)
  万代　道子
- Total Pages
  5
- Publisher
  日本医師会
- Data Source
  KAKENHI-PROJECT-24592688
[Book] 多能性幹細胞を用いた加齢黄斑変性の細胞移植治療,医学のあゆみ2011
- Author(s)
  万代道子、高橋政代
- Data Source
  KAKENHI-PROJECT-21592270
[Book] 医学のあゆみ2011
- Author(s)
  万代道子、高橋政代
- Total Pages
  4
- Publisher
  多能性幹細胞を用いた加齢黄斑変性の細胞移植治療
- Data Source
  KAKENHI-PROJECT-21592270
[Book] 実験医学26、網膜疾患の再生医療第2章幹細胞の臨床応用、7頁2008
- Author(s)
  万代道子・高橋政代
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-19592049
[Book] 網膜の再生医療第3章臨床応用への道ティッシュエンジニアリング2007、6頁2007
- Author(s)
  高橋政代・万代道子
- Publisher
  日本組織工学会監修日本医学館
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] Establishment of Immunodeficient Retinal Degeneration Model Mice and Functional Maturation of Human ESC-Derived Retinal Sheets after Transplantation2018
- Author(s)
  Iraha Satoshi、Tu Hung-Ya、Yamasaki Suguru、Kagawa Takahiro、Goto Motohito、Takahashi Riichi、Watanabe Takehito、Sugita Sunao、Yonemura Shigenobu、Sunagawa Genshiro A.、Matsuyama Take、Fujii Momo、Kuwahara Atsushi、Kishino Akiyoshi、Koide Naoshi、Eiraku Mototsugu、Tanihara Hidenobu、Takahashi Masayo、Mandai Michiko
- Journal Title
  
  Stem Cell Reports
  
  Volume: 10 Pages: 1059-1074
- DOI
  10.1016/j.stemcr.2018.01.032
- NAID
  120007037461
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16994, KAKENHI-PROJECT-15KT0086, KAKENHI-PROJECT-17H04351, KAKENHI-PROJECT-15K10913, KAKENHI-PROJECT-18H02959, KAKENHI-PROJECT-16K21633
[Journal Article] iPSC-derived retina transplants improve vision in rd1 end-stage retinal degeneration mice2017
- Author(s)
  Mandai M, Fujii M, Hashiguchi T, Sunagawa GA, Ito S, Sun J, Kaneko J, Sho J, Yamada C, Takahashi M
- Journal Title
  
  Stem Cell Reports
  
  Volume: 8 Pages: 69-83
- DOI
  10.1016/j.stemcr.2016.12.008
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K10913
[Journal Article] Protective effects of human iPS-derived retinal pigmented epithelial cells in comparison with human mesenchymal stromal cells and human neural stem cells on the degenerating retina in rd1 mice.2015
- Author(s)
  Sun J, Mandai M, Kamao H, Hashiguchi T, Shikamura M, Kawamata S, Sugita S, Takahashi M.
- Journal Title
  
  Stem Cells
  
  Volume: 33（5） Pages: 1543-1553
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592688
[Journal Article] Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice.2014
- Author(s)
  Juthaporn Assawachananont, Michiko Mandai, Satoshi Okamoto, Chikako Yamada, Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, Masayo Takahashi.
- Journal Title
  
  Stem Cell Reports
  
  Volume: 2（5） Pages: 662-674
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592688
[Journal Article] Transplantation of Embryonic and Induced Pluripotent Stem Cell-Derived 3D Retinal Sheets into Retinal Degenerative Mice2014
- Author(s)
  Juthaporn Assawachananont, Michiko Mandai,* Satoshi Okamoto, Chikako Yamada,Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, and Masayo Takahashi
- Journal Title
  
  Stem Cell Reports
  
  Volume: 2(5) Pages: 662-674
- DOI
  10.1016/j.stemcr.2014.03.011
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24592688
[Journal Article] Developing rods transplanted into the degenerating retina of Crx-knockout mice exhibit neural activity similar to native photoreceptors.2013
- Author(s)
  Homma K、Okamoto S、Mandai M、Gotoh N、ajasimha HK、Chang YS、Chen S、Li W、Cogliati T 、Swaroop A 、Takahashi M
- Journal Title
  
  Stem Cells
  
  Volume: (印刷中) Pages: 1149-1159
- DOI
  10.1002/stem.1372
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22791702, KAKENHI-PROJECT-23592561, KAKENHI-PROJECT-24592688
[Journal Article] Use of lectins to enrich mouse ES-derived retinal progenitor cells for the purpose of transplantation therapy2010
- Author(s)
  Mandai M, Ikeda H, Jin ZB, Iseki K, Ishigami C, Takahashi M
- Journal Title
  
  Cell Transplantation
  
  Volume: 19 Pages: 9-19
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592270
[Journal Article] Detection of Localized Retinal Malfunction in Retinal Degeneration Model Using a Multielectrode Array System2009
- Author(s)
  Homma K, Osakada F, Hirami Y, Jin ZB, Mandai M, Takahashi M
- Journal Title
  
  J Neurosci Res
  
  Volume: 87 Pages: 2175-2182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592270
[Journal Article] Detection of Localized Retinal Malfunction in Retinal Degeneration Model Using a Multielectrode Array System2009
- Author(s)
  Homma K, Osakada F, Hirami Y, Jin ZB, Mandai M, Takahashi M
- Journal Title
  
  J Neurosci Res 87
  
  Pages: 2175-2182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592270
[Journal Article] Toward the generation of rod and cone potoreceptors from mouse,monkey and human embryonic stem cells.2008
- Author(s)
  Osakada F, Ikeda H, Mandai M, Wataya T, Watanabe K, Yoshimura N, Akaike A, Sasai Y, Takahashi M..
- Journal Title
  
  Nat Biotechnol. 26(2)
  
  Pages: 215-24
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] Toward the generation of rod and cone photoreceptors from mouse, monkey and human embryonic stem cells2008
- Author(s)
  Osakada F, Ikeda H, Mandai M, Wataya T, Watanabe K, Yoshimura N, Akaike A, Sasai Y, Takahashi M
- Journal Title
  
  Nature Biotechnology 26
  
  Pages: 215-224
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] Detection of localized retinal malfunction in retinal degeneration model using a multi-electrode array system2008
- Author(s)
  Homma K, Osakada F, Hirami Y, Jin ZB, Mandai M, Takahashi M
- Journal Title
  
  J Neurosci Res. 2552
  
  Pages: 2175-2182
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] Chondroitinase ABC Treatment Enhances Synaptogenesis Between Transplamt and Host Neurons in Model of Retinal Degeneration2007
- Author(s)
  Suzuki T, Akimoto M, Imai H, Ueda Y, Mandai M, Yoshimura N, Swaroop A, Takahashi M
- Journal Title
  
  Cell Transplantation 16
  
  Pages: 493-503
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] The effect of dendritic cells on the retinal cell transplantation2007
- Author(s)
  Oishi A, Nagai T, Mandai M, Takahashi M, Yoshimura N
- Journal Title
  
  Biochemical and Biophysical Research Communications 363
  
  Pages: 292-296
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] Use of lectins to enrich mouse ES-derived retinal progenitor cells for the purpose of transplantation therapy
- Author(s)
  Michiko Mandai
- Journal Title
  
  Stem cells
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19592049
[Journal Article] Use of lectins to enrich mouse ES-derived retinal progenitor cells for the purpose of transplantation therapy
- Author(s)
  Mandai M, Ikeda H, Jin ZB, Iseki K, Ishigami C, Takahashi M
- Journal Title
  
  Cell Transplantation (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21592270
[Patent] 移植用細胞集団及びその製造方法2016
- Inventor(s)
  万代道子、高橋政代、山崎優
- Industrial Property Rights Holder
  国立研究開発法人理研研究所、大日本住友製薬株式会社
- Industrial Property Rights Type
  特許
- Filing Date
  2016-11-25
- Data Source
  KAKENHI-PROJECT-15K10913
[Presentation] iPS細胞を用いた網膜再生医療2021
- Author(s)
  万代道子
- Organizer
  第20回日本再生医療学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] 網膜色素変性に対するiPS由来網膜移植治療2021
- Author(s)
  万代道子
- Organizer
  第40回日本眼薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] 次世代型ヒトES細胞由来網膜組織の末期網膜変性ラットへの移植後の表現型2020
- Author(s)
  万代道子
- Organizer
  第124回日本眼科学学会総会
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] iPS由来網膜シートを用いた再生医療2020
- Author(s)
  万代道子
- Organizer
  第21回日本ロービジョン学会学術総会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] iPS由来網膜組織を用いた再生治療2019
- Author(s)
  万代道子
- Organizer
  日本眼科学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] Regeneration therapy for retinal degeneration using iPS cell-derived retinal tissue2019
- Author(s)
  万代道子
- Organizer
  眼薬理学会
- Invited
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] Transplantation of ES/iPS-derived 3D retina～Over view of current work2019
- Author(s)
  万代　道子
- Organizer
  10 Years Vision Research in Paris
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] ヒトiPS 細胞由来網膜移植後のラット及びサル網膜変性モデルでの中長期生着と機能検証2019
- Author(s)
  万代道子　 Tu Hung-Y ほか
- Organizer
  日本眼科学会
- Data Source
  KAKENHI-PROJECT-19K09942
[Presentation] Regeneration therapy using IPS-derived retinal cells2017
- Author(s)
  万代道子
- Organizer
  EURETINA
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10913
[Presentation] 網膜末期変性モデルへのiPS由来網膜組織移植後の視機能評価2017
- Author(s)
  万代道子
- Organizer
  ConBio2017（2017年度生命科学系学会合同年次大会）
- Invited
- Data Source
  KAKENHI-PROJECT-15K10913
[Presentation] iPS由来網膜を用いた末期網膜変性モデルマウスの視機能改善2017
- Author(s)
  万代道子
- Organizer
  第121回日本眼科学会
- Data Source
  KAKENHI-PROJECT-15K10913
[Presentation] IPS CELL-DERIVED RETINAL CELL TRANSPLANTATION2017
- Author(s)
  万代道子
- Organizer
  第58回日本神経学会学術大会
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K10913
[Presentation] Regeneration therapy for retinal degeneration2015
- Author(s)
  Michiko Mandai
- Organizer
  Asia-ARVO 2015
- Place of Presentation
  Yokohama,JAPAN
- Year and Date
  2015-02-19
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] Retinal regeneration therapy for retinal degenaration using ES/iPS derived retinal tissue2015
- Author(s)
  Michiko Mandai
- Organizer
  Asia-ARVO 2015
- Place of Presentation
  Yokohama,JAPAN
- Year and Date
  2015-02-18
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] iPS細胞由来細胞/組織を用いた網膜再生医療2014
- Author(s)
  万代　道子
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-17
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] Light-evoked Response Recordings from Degenerating Mouse Retina: Effect of Valproic Acid Application on Spontaneous Activity2013
- Author(s)
  Jun Kaneko, Michiko Mandai, Masayo Takahashi
- Organizer
  ＡＲＶＯ2013
- Place of Presentation
  Seattle, Washington.U.S.A
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] Presentation Title: Differentiation and transplantation of mouse ESC- and iPSC-derived retina-like sheets in retinal degeneration mouse2013
- Author(s)
  Juthaporn Assawachananont, Michiko Mandai, Satoshi Okamaoto, Jun Kaneko, Chikako Yamada, Mototsugu Eiraku, Shigenobu Yonemura, Yoshiki Sasai, Masayo
- Organizer
  ＡＲＶＯ2013
- Place of Presentation
  Seattle, Washington.U.S.A
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] マウス網膜変性モデルでの視細胞移植2011
- Author(s)
  万代道子
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] Preparation of iPS-derived RPE Sheets for Transplantation Therapy2011
- Author(s)
  Hiroyuki Kamao, Satoshi Okamoto, Michiko Mandai, Yasuhiko Hirami, Junichi Kiryu, Masayo Takahashi
- Organizer
  ARVO 2011 Annual Meeting
- Place of Presentation
  Fort Lauderdale, FL, U.S.A
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] A prototype instrument for subretinal transplantation of retinal pigment epithelial cell sheets2011
- Author(s)
  Hirami Y, Kurimoto Y, Konishi S, Mita O, Harada N, Kamao H, Mandai M, Kiryu J, Takahashi M
- Organizer
  第50回日本網膜硝子体学会総会
- Place of Presentation
  東京
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 視細胞移植と網膜機能2011
- Author(s)
  金子潤、万代道子、本間耕平、高橋政代
- Organizer
  第15回視覚科学フォーラム
- Place of Presentation
  大阪大学,大阪
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] A prototype instrument for subretinal transplantation of retinal pigmentepithelial cell sheets2011
- Author(s)
  Hirami Y, Kurimoto Y, Konishi S, Mita O, Harada N, Kamao H, Mandai M, Kiryu J, Takahashi M
- Organizer
  第50回日本網膜硝子体学会総会
- Place of Presentation
  東京国際フォーラム,東京
- Year and Date
  2011-12-03
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 移植網膜の機能評価2011
- Author(s)
  万代道子
- Organizer
  第65回日本臨床眼科学会
- Place of Presentation
  東京
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] マウス網膜変性モデルでの視細胞移植2011
- Author(s)
  万代道子
- Organizer
  第10回日本再生医療学会総会
- Place of Presentation
  東京都・京王プラザホテル
- Year and Date
  2011-03-02
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 移植網膜の機能評価2011
- Author(s)
  万代道子
- Organizer
  第65回日本臨床眼科学会
- Place of Presentation
  東京国際フォーラム,東京
- Year and Date
  2011-10-07
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 視細胞移植と網膜機能2011
- Author(s)
  金子潤、万代道子、本間耕平、高橋政代
- Organizer
  第15回視覚科学フォーラム
- Place of Presentation
  大阪
- Year and Date
  2011-08-29
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] Preparation of iPS-derived RPE Sheets for Transplantation Therapy2011
- Author(s)
  Hiroyuki Kamao, Satoshi Okamoto, Michiko Mandai, Yasuhiko Hirami, Junichi Kiryu, Masayo Takahashi
- Organizer
  ARVO 2011 Annual Meeting
- Place of Presentation
  Fort Lauderdale, FL. U. S. A
- Year and Date
  2011-05-04
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] マウス変性網膜への視細胞移植の条件検討2010
- Author(s)
  万代道子
- Organizer
  第114回日本眼科学会
- Place of Presentation
  名古屋市・名古屋国際会議場
- Year and Date
  2010-04-16
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] Neuronal activities of transplanted retinal cells in retinal degeneration models2010
- Author(s)
  Kohei homma, Satoshi Okamoto, Michiko Mandai, Masayo Takahashi
- Organizer
  40th Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜変性マウスにおける移植網膜視細胞の神経活動2010
- Author(s)
  本間耕平, 万代道子, 金子兵, 高橋政代
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  神戸市・神戸コンベンションセンター
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜の移植による再生医療2010
- Author(s)
  万代道子
- Organizer
  第42回日本臨床分子形態学会総会
- Place of Presentation
  静岡
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] Measurement Of Neuronal Activities Of Transplanted Retinal Cells In Retinal Degeneration Models2010
- Author(s)
  Kohei Homma, Zi-Bing Jin, Michiko Mandai, Masayo Takahashi
- Organizer
  The Association for Research in Vision and Ophthalmology
- Place of Presentation
  Fort Lauderdale, FL, USA
- Year and Date
  2010-05-06
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜変性マウスにおける移植網膜視細胞の神経活動2010
- Author(s)
  本間耕平,万代道子,金子兵,高橋政代
- Organizer
  第33回日本神経科学大会
- Place of Presentation
  兵庫神戸
- Year and Date
  2010-09-02
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] Neuronal activities of transplanted retinal cells in retinal degeneration models2010
- Author(s)
  Kohei Homma, Satoshi Okamoto, Michiko Mandai, Masayo Takahashi
- Organizer
  40^<th> Society for Neuroscience
- Place of Presentation
  San Diego, CA, USA
- Year and Date
  2010-11-16
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] マウス変性網膜への視細胞移植の条件検討2010
- Author(s)
  万代道子
- Organizer
  第114回日本眼科学会
- Place of Presentation
  愛知名古屋
- Year and Date
  2010-04-06
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜の移植による再生医療2010
- Author(s)
  万代道子
- Organizer
  第42回日本臨床分子形態学会総会
- Place of Presentation
  三島市・東レ研修センター
- Year and Date
  2010-09-25
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜変性マウスにおける移植網膜視細胞の神2010
- Author(s)
  本間耕平,万代道子,高橋政代
- Organizer
  第14回視覚科学フォーラム研究会
- Place of Presentation
  茨城県つくば
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜変性マウスにおける移植網膜視細胞の神経活動計測2010
- Author(s)
  本間耕平, 万代道子, 高橋政代
- Organizer
  第14回視覚科学フォーラム研究会
- Place of Presentation
  つくば市・筑波大学
- Year and Date
  2010-08-27
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] マウス網膜への視細胞移植の条件検討2009
- Author(s)
  万代道子
- Organizer
  第8回日本再生医療学会総会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] マウス変性網膜への視細胞移植2009
- Author(s)
  万代道子
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京都、東京国際フォーラム
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] マウス変性網膜への視細胞移植2009
- Author(s)
  万代道子
- Organizer
  第113回日本眼科学会総会
- Place of Presentation
  東京
- Year and Date
  2009-04-24
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜の再生医療2009
- Author(s)
  万代道子
- Organizer
  ヒト細胞学会
- Place of Presentation
  東京
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 網膜の再生医療2009
- Author(s)
  万代道子
- Organizer
  ヒト細胞学会
- Place of Presentation
  東京都、東京慈恵会医科大学
- Year and Date
  2009-08-22
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] マウス変性網膜への視細胞移植2009
- Author(s)
  万代道子
- Organizer
  厚生労働省難治性疾患克服研究事業網膜脈絡膜・視神経萎縮症調査研究班平成20年度班会議
- Place of Presentation
  名古屋市立大学病棟・中央診療棟3F大ホール
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] Retinal transplantation therapy for rd1 mice Okinawa Institute of Science and Technology International Workshop2009
- Author(s)
  万代道子
- Organizer
  Retina : Neural Stem Cells and Photoreceptor Degeneration
- Place of Presentation
  沖縄
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] Retinal transplantation therapy for rd1 mice2009
- Author(s)
  万代道子
- Organizer
  Okinawa Institute of Science and Technology International Workshop "Retina : Neural Stem Cells and Photoreceptor Degeneration"
- Place of Presentation
  沖縄県恩納村
- Year and Date
  2009-11-10
- Data Source
  KAKENHI-PROJECT-21592270
[Presentation] 多点電極測定系による網膜変性モデルにおける視細胞機能の複数点同時計測2008
- Author(s)
  本間耕平・万代道子
- Organizer
  第46回日本生物物理学会年会
- Place of Presentation
  福岡国際会議場
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] 網膜の再生医療をめざして2008
- Author(s)
  万代道子
- Organizer
  第7回日本再生医療学会総会
- Place of Presentation
  名古屋
- Year and Date
  2008-03-14
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] 網膜再生治療開発の戦略眼科幹細胞研究の現状2008
- Author(s)
  万代道子
- Organizer
  第112回日本眼科学会総会
- Place of Presentation
  パシフィコ横浜
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] 多点電極測定系によるMNU網膜変性モデルを用いた網膜神経機能測定法の評価2008
- Author(s)
  本間耕平・万代道子
- Organizer
  第31回日本神経科学大会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] 移植ホスト網膜の環境の検討-成体網膜と新生児網膜2008
- Author(s)
  万代道子
- Organizer
  第62回日本臨床眼科学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] 移植時ホスト網膜の環境の検討-成体網膜と新生児網膜2008
- Author(s)
  万代道子
- Organizer
  第62回日本臨床眼科学会
- Place of Presentation
  東京国際フォーラム
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] ヒトおよびサルES細胞からの網膜色素上皮および視細胞分化誘導、2007
- Author(s)
  万代道子
- Organizer
  第111回日本眼科学会総会
- Place of Presentation
  大阪
- Data Source
  KAKENHI-PROJECT-19592049
[Presentation] 網膜変性マウスに対するES/iPS由来細胞網膜の移植治療
- Author(s)
  万代　道子
- Organizer
  第66回日本臨床眼科学会
- Place of Presentation
  国立京都国際会館,京都
- Invited
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] Differentiation and Transplantation of Mouse ES and iPS Derived Retina-like Sheets in Retinal Degeneration Mouse (rd1) Paper Session.
- Author(s)
  Juthaporn Assawachananont, Michiko Mandai, Satoshi Okamoto, Jun Kaneko, Mototsugu Eiraku, Yoshiki Sasai, Masayo Takahashi
- Organizer
  ARVO2012
- Place of Presentation
  Greater Fort Lauderdale/Broward County Convention Center,Fort Lauderdale, Fl, USA
- Data Source
  KAKENHI-PROJECT-24592688
[Presentation] Electrophysiological Evaluation of Mouse ES and iPS Derived Retina-like Sheet Transplantation in Retinal Degeneration Mouse Poster Session.
- Author(s)
  Jun Kaneko, Michiko Mandai, Juthaporn Assawachananont, Satoshi Okamoto, Mototsugu Eiraku, Yoshiki Sasai, Masayo Takahashi
- Organizer
  ARVO2012
- Place of Presentation
  Greater Fort Lauderdale/Broward County Convention Center ,Fort Lauderdale, Fl, USA
- Data Source
  KAKENHI-PROJECT-24592688

1. TAKAHASHI Masayo (80252443)

# of Collaborated Projects: 12 results

# of Collaborated Products: 33 results
2. KASHII Satoshi (50194717)

# of Collaborated Projects: 7 results

# of Collaborated Products: 0 results
3. TAKAGI Hitoshi (70283596)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
4. HONDA Yoshihito (90026930)

# of Collaborated Projects: 6 results

# of Collaborated Products: 0 results
5. TANIHARA Hidenobu (60217148)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
6. 栗山晶治 (50260625)

# of Collaborated Projects: 4 results

# of Collaborated Products: 0 results
7. KIRYU Junichi (80281096)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
8. SUZUMA Kiyoshi (80335265)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
9. NISHIWAKI Hirokazu (90303841)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
10. AKIMOTO Masayuki (90303453)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
11. 吉村長久 (70211662)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
12. 岡本直之 (70263069)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
13. HOMMA Kohei (80462729)

# of Collaborated Projects: 1 results

# of Collaborated Products: 11 results
14. TANABE Masayo (80243020)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. KOSUGI Shinji (50252432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 喜多美穂里 (00252453)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 前田亜希子 (40776423)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 大西暁士 (70569102)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 砂川玄志郎 (70710250)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
20. Tu HungYa (10780835)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
21. 高須正行

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
22. OKAMOTO Satoshi

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
23. 米村重信

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
24. 高橋枝里

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
25. 杉田直

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
26. 小出直史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MANDAI Michiko 万代 道子

万代 道子 マンダイ ミチコ

MANDEI Michiko 万代 道子

Research Projects

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ES/iPS細胞由来網膜移植の機能的生着向上のためのホスト網膜環境に関する研究Principal Investigator

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ES/iPS由来網膜組織を用いた実用的な視機能再建のための次世代治療の開発Principal Investigator

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Development of new types of ES/iPS-retina for better synaptic integrationPrincipal Investigator

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Evaluaton of ES/iPS-retinal sheettransplantation in reference to retinal cell transplantation in mouse retnal degeneration modelPrincipal Investigator

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Modulation of host environment in retinal cell transplantation using retinal degeneration models.Principal Investigator

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Detailed studies on the conditions of ES derived photoreceptor precursors and the host retinal environment for the successful transplantationPrincipal Investigator

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Multi-analytic approach to the understanding of the patho-physiology of retinitis pigmentosa and related diseases using genetic, immunologic and clinical imaging methodsPrincipal Investigator

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眼内新生血管における性差とその病態機序及び治療におけるエストロゲンの役割Principal Investigator

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MANDAI Michiko 万代道子

万代道子マンダイミチコ

MANDEI Michiko 万代道子