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Sunagawa Genshiro  砂川 玄志郎

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Genshiro Sunagawa  砂川 玄志郎

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Researcher Number 70710250
Other IDs
Affiliation (Current) 2022: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 上級研究員
Affiliation (based on the past Project Information) *help 2020 – 2021: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 上級研究員
2018 – 2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 基礎科学特別研究員
2015: 国立研究開発法人理化学研究所, 多細胞システム形成研究セン ター, 研究員
2015: 国立研究開発法人理化学研究所, 多細胞システム形成研究センター, 研究員
2014: 独立行政法人理化学研究所, 生命システム研究センター, 研究員
Review Section/Research Field
Principal Investigator
Neurophysiology / General neuroscience / Animal physiology/Animal behavior / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Transformative Research Areas, Section (III) / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related / Basic Section 55060:Emergency medicine-related / Medium-sized Section 50:Oncology and related fields
Keywords
Principal Investigator
休眠 / 冬眠 / 能動的低代謝 / マウス / 低温耐性 / QIH / 睡眠時間 / NMDA / CRISPR / Nr3a … More / カルシウム / 睡眠恒常性 / SSS / カルシウムイオン / 睡眠 / 覚醒 / 非侵襲 / 機能的MRI / 非侵襲代謝評価 / CAGE解析 / 低体温 / ハムスター / 日内休眠 / 低代謝耐性 / 急性疾患 / 冬眠の臨床応用 / 搬送医療 … More
Except Principal Investigator
能動的低代謝 / 冬眠 / 休眠 / 低体温循環停止法 / ヒトiPS細胞 / 病態モデル / 臓器保護 / 組織保存 / オルガノイド / 日内休眠 / 組織保存法 / 網膜シート / 低温耐性 / 低代謝耐性 / 再生医療 / 低代謝療法 / がん / 人工冬眠 Less
  • Research Projects

    (10 results)
  • Research Products

    (48 results)
  • Co-Researchers

    (25 People)
  •  休眠時低温耐性を理解するためのマウスを用いた新規in vitro評価系の開発Host Researcher

    • Host Researcher
      砂川 玄志郎
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for JSPS Fellows
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  低代謝療法の基盤となる脳から末梢組織への休眠シグナルの解明

    • Principal Investigator
      大鶴 繁
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55060:Emergency medicine-related
    • Research Institution
      Kyoto University
  •  Can hibernation delay acute illness and improve outcome?Principal Investigator

    • Principal Investigator
      砂川 玄志郎
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Challenging Research (Pioneering)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  人工冬眠マウスモデルを用いた新規がん治療標的の探索

    • Principal Investigator
      向井 英史
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 50:Oncology and related fields
    • Research Institution
      Nagasaki University
  •  The molecular mechanisms of active hypometabolismPrincipal Investigator

    • Principal Investigator
      砂川 玄志郎
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Transformative Research Areas (B)
    • Review Section
      Transformative Research Areas, Section (III)
    • Research Institution
      Institute of Physical and Chemical Research
  •  低体温循環停止における「人工冬眠」併用による効率的な臓器保護法の開発

    • Principal Investigator
      川東 正英
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Kyoto University
  •  Development of a novel tissue preservation method via mammalian hypometabolism

    • Principal Investigator
      高橋 政代
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
    • Research Institution
      Institute of Physical and Chemical Research
  •  Functional MRI Brain imaging in Torpid MicePrincipal Investigator

    • Principal Investigator
      Genshiro Sunagawa
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 44050:Animal physiological chemistry, physiology and behavioral biology-related
    • Research Institution
      Institute of Physical and Chemical Research
  •  Hypothermia in inbred micePrincipal Investigator

    • Principal Investigator
      砂川 玄志郎
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Research Institution
      Institute of Physical and Chemical Research
  •  Understanding the design principles of of sleep/wake dynamics in mammalsPrincipal Investigator

    • Principal Investigator
      Sunagawa Genshiro
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Neurophysiology / General neuroscience
      Animal physiology/Animal behavior
    • Research Institution
      Institute of Physical and Chemical Research

All 2020 2019 2018 2016 2015 2014

All Journal Article Presentation Patent

  • [Journal Article] A Discrete Neuronal Circuit that induces Hibernation-like State in Rodents.2020

    • Author(s)
      Takahashi TM, Sunagawa GA, Soya S, Abe M, Sakurai K, Ishikawa K, Yanagisawa M, Hama H, Hasegawa E, Miyawaki A, Sakimura K, Takahashi M, Sakurai T
    • Journal Title

      Nature

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Journal Article] 睡眠と冬眠と代謝2020

    • Author(s)
      砂川 玄志郎
    • Journal Title

      睡眠医療

      Volume: 13 Pages: 137-141

    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Journal Article] 休眠とその医学応用可能性2020

    • Author(s)
      砂川玄志郎
    • Journal Title

      実験医学

      Volume: 6 Pages: 978-981

    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Journal Article] A discrete neuronal circuit induces a hibernation-like state in rodents2020

    • Author(s)
      Takahashi TM, Sunagawa GA, Soya S, Abe M, Sakurai K, Ishikawa K, Yanagisawa M, Hama H, Hasegawa E, Miyawaki A, Sakimura K, Takahashi M, Sakurai T.
    • Journal Title

      Nature

      Volume: - Pages: 109-114

    • DOI

      10.1038/s41586-020-2163-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0070, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-19K09241, KAKENHI-PROJECT-18KK0458, KAKENHI-ORGANIZER-16H06400, KAKENHI-PLANNED-16H06401, KAKENHI-PUBLICLY-19H04894, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-18H02595, KAKENHI-PROJECT-19J20876, KAKENHI-PROJECT-19K22465
  • [Journal Article] 休眠とその医学応用可能性2020

    • Author(s)
      砂川玄志郎
    • Journal Title

      実験医学

      Volume: 6 Pages: 978-981

    • Data Source
      KAKENHI-PLANNED-20H05767
  • [Journal Article] 休眠とその医学応用可能性2020

    • Author(s)
      砂川玄志郎
    • Journal Title

      実験医学

      Volume: 6 Pages: 978-981

    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Journal Article] A Discrete Neuronal Circuit that induces Hibernation-like State in Rodents.2020

    • Author(s)
      Takahashi TM, Sunagawa GA, Soya S, Abe M, Sakurai K, Ishikawa K, Yanagisawa M, Hama H, Hasegawa E, Miyawaki A, Sakimura K, Takahashi M, Sakurai T
    • Journal Title

      Nature

      Volume: -

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Journal Article] 睡眠と冬眠と代謝2019

    • Author(s)
      砂川 玄志郎
    • Journal Title

      睡眠医療

      Volume: 13 Pages: 137-141

    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Journal Article] 睡眠と冬眠と代謝2019

    • Author(s)
      砂川 玄志郎
    • Journal Title

      睡眠医療

      Volume: 13 Pages: 137-141

    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Journal Article] Involvement of Ca2+-Dependent Hyperpolarization in Sleep Duration in Mammals2016

    • Author(s)
      Fumiya Tatsuki, Genshiro A. Sunagawa, Shoi Shi, Etsuo A. Susaki, Hiroko Yukinaga, Dimitri Perrin, Kenta Sumiyama, Maki Ukai-Tadenuma, Hiroshi Fujishima, Rei-ichiro Ohno, Daisuke Tone, Koji L. Ode, Katsuhiko Matsumoto, Hiroki R. Ueda
    • Journal Title

      Neuron

      Volume: 印刷中 Pages: 70-85

    • DOI

      10.1016/j.neuron.2016.02.032

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-23115006, KAKENHI-PUBLICLY-26113720, KAKENHI-PROJECT-15H05650, KAKENHI-PROJECT-14J06417, KAKENHI-PROJECT-26870858, KAKENHI-PROJECT-25221004
  • [Journal Article] Mammalian Reverse Genetics without Crossing Reveals Nr3a as a Short-Sleeper Gene2016

    • Author(s)
      Sunagawa GA, Sumiyama K, Ukai-Tadenuma M, Perrin D, Fujishima H, Ukai H, Nishimura O, Shi S, Ohno R, Narumi R, Shimizu Y, Tone D, Ode KL, Kuraku S, Ueda HR.
    • Journal Title

      Cell Reports

      Volume: 14 Pages: 1-16

    • DOI

      10.1016/j.celrep.2015.12.052

    • Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26640134, KAKENHI-PLANNED-23115006, KAKENHI-PUBLICLY-26113720, KAKENHI-PROJECT-25221004, KAKENHI-PROJECT-14J06417, KAKENHI-PROJECT-26870858, KAKENHI-PROJECT-26710014
  • [Patent] 冬眠様状態を誘発する方法およびそのための装置2019

    • Inventor(s)
      櫻井武、高橋徹、砂川玄志郎
    • Industrial Property Rights Holder
      櫻井武、高橋徹、砂川玄志郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Patent] 冬眠様状態を誘発する方法およびそのための装置2019

    • Inventor(s)
      櫻井武、高橋徹、砂川玄志郎
    • Industrial Property Rights Holder
      櫻井武、高橋徹、砂川玄志郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Patent] 冬眠様状態を誘発する方法およびそのための装置2019

    • Inventor(s)
      櫻井武、高橋徹、砂川玄志郎
    • Industrial Property Rights Holder
      櫻井武、高橋徹、砂川玄志郎
    • Industrial Property Rights Type
      特許
    • Filing Date
      2019
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] A discrete neuronal circuit induces a hibernation-like state in rodents2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      Hibernation Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PLANNED-20H05767
  • [Presentation] 冷たいことには理由がある ~冬眠から考える人類の未来~2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      日本神経科学大会 市民公開パネルディスカッション「2050年の脳科学と社会」
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] 冷たいことには理由がある ~冬眠から考える人類の未来~2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      日本神経科学大会 市民公開パネルディスカッション「2050年の脳科学と社会」
    • Data Source
      KAKENHI-PLANNED-20H05767
  • [Presentation] A hibernation-like condition in mice: the physiological aspects of Q neurons-induced hypometabolism.2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      第43回 分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Presentation] A hibernation-like condition in mice: the physiological aspects of Q neurons-induced hypometabolism.2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      第43回 分子生物学会年会
    • Data Source
      KAKENHI-PLANNED-20H05767
  • [Presentation] A discrete neuronal circuit induces a hibernation-like state in rodents2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      Hibernation Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] 冷たいことには理由がある ~冬眠から考える人類の未来~2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      日本神経科学大会 市民公開パネルディスカッション「2050年の脳科学と社会」
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Presentation] A hibernation-like condition in mice: the physiological aspects of Q neurons-induced hypometabolism.2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      第43回 分子生物学会年会
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] A discrete neuronal circuit induces a hibernation-like state in rodents2020

    • Author(s)
      砂川 玄志郎
    • Organizer
      Hibernation Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Presentation] Daily torpor in mice as a model of active hypometabolism in mammals2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      NEURO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] マウスを用いた人工冬眠の研究2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第63回 宇宙科学技術連合講演会
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] 冬眠の臨床応用に向けて:能動的低代謝を体温管理療法に応用できるか?2019

    • Author(s)
      砂川 玄志郎
    • Organizer
      第22回日本脳低温療法・体温管理学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Presentation] Toward clinical application of active hypometabolism2019

    • Author(s)
      Genshiro A Sunagawa
    • Organizer
      The 9th Federation of Asian and Oceanian Physiological Societies Congress
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] 冬眠のひみつ2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      文部科学省 新学術領域研究 「温度生物学」 市民公開講座
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] マウス休眠をモデルとした能動的低代謝の研究: 骨格筋における休眠特異的遺伝子発現の解析2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第3回冬眠休眠研究会
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] マウス休眠をモデルとした能動的低代謝の研究: 骨格筋における休眠特異的遺伝子発現の解析2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第3回冬眠休眠研究会
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] 冬眠の臨床応用に向けて:能動的低代謝を体温管理療法に応用できるか?2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第22回日本脳低温療法・体温管理学会学術集会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] Daily torpor in mice as a model of active hypometabolism in mammals2019

    • Author(s)
      砂川 玄志郎
    • Organizer
      NEURO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Presentation] マウスの日内休眠における骨格筋の遺伝子発現の変化2019

    • Author(s)
      砂川 玄志郎
    • Organizer
      第22回日本脳低温療法・体温管理学会学術集会
    • Data Source
      KAKENHI-PROJECT-19H01066
  • [Presentation] 冬眠の臨床応用に向けて:能動的低代謝を体温管理療法に応用できるか?2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第22回日本脳低温療法・体温管理学会学術集会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] Daily torpor in mice as a model of active hypometabolism in mammals2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      NEURO2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] 冬眠のひみつ2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      文部科学省 新学術領域研究 「温度生物学」 市民公開講座
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] マウスを用いた人工冬眠の研究2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第63回 宇宙科学技術連合講演会
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] マウスの日内休眠における骨格筋の遺伝子発現の変化2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第22回日本脳低温療法・体温管理学会学術集会
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] マウスの日内休眠における骨格筋の遺伝子発現の変化2019

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      第22回日本脳低温療法・体温管理学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] Toward clinical application of active hypometabolism: studying active hypometabolism via mouse daily torpor as a model system2018

    • Author(s)
      Genshiro A Sunagawa
    • Organizer
      Torpor and Metabolism Workshop
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] Toward clinical application of active hypometabolism: using mouse daily torpor as a model system2018

    • Author(s)
      Genshiro A Sunagawa
    • Organizer
      Life of genomes - 2018
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] Physiological Phenotyping by Non-invasive Respiratory Recordings2018

    • Author(s)
      Genshiro A Sunagawa
    • Organizer
      The 41st Annual Meeting of the Molecular Biology Society of Japan
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-18H04706
  • [Presentation] Physiological Phenotyping by Non-invasive Respiratory Recordings2018

    • Author(s)
      Genshiro A Sunagawa
    • Organizer
      The 41st Annual Meeting of the Molecular Biology Society of Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K06347
  • [Presentation] Screening complex biological systems at organismal level: sleep and hibernation.2016

    • Author(s)
      Genshiro A. Sunagawa.
    • Organizer
      Kanazawa University Brain/Liver Interface Medicine Research Center Symposium
    • Place of Presentation
      金沢大学・金沢市・石川県
    • Year and Date
      2016-03-07
    • Invited
    • Data Source
      KAKENHI-PROJECT-26870858
  • [Presentation] Screening complex organismal level biological systems : sleep and hibernation2016

    • Author(s)
      Genshiro A. Sunagawa.
    • Organizer
      SRI Biosciences Division seminar
    • Place of Presentation
      SRI・サンフランシスコ・アメリカ
    • Year and Date
      2016-07-29
    • Data Source
      KAKENHI-PROJECT-26870858
  • [Presentation] Toward hypometabolic organ preservation: the development of stable induction method for mouse torpor.2016

    • Author(s)
      Genshiro A. Sunagawa, Masayo Takahashi.
    • Organizer
      The 15th Congress of the Japanese Society for Regenerative Medicine
    • Place of Presentation
      大阪国際会議場・大阪市・大阪府
    • Year and Date
      2016-03-19
    • Data Source
      KAKENHI-PROJECT-26870858
  • [Presentation] Next-generation Sleep Phenotyping System for Mice.2015

    • Author(s)
      Genshiro A. Sunagawa, Hiroki R. Ueda.
    • Organizer
      The 38th Annual Meeting of the Japan Neuroscience Society
    • Place of Presentation
      国際会議場・神戸市・兵庫県
    • Year and Date
      2015-07-30
    • Data Source
      KAKENHI-PROJECT-26870858
  • [Presentation] Next-generation Sleep Phenotyping System for Mice.2014

    • Author(s)
      Genshiro A. Sunagawa
    • Organizer
      Homeodynamics in Clocks, Sleep and Metabolism, TOKYO TRANSLATIONAL THERAPEUTICS MEETING
    • Place of Presentation
      Ito Hall, Ito International Research Center, The University of Tokyo
    • Year and Date
      2014-09-24
    • Data Source
      KAKENHI-PROJECT-26870858
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  • 16.  SHIMIZU Yoshihiro
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  • 18.  阿部 学
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  • 19.  征矢 英昭
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  • 20.  桜井 武
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  • 21.  崎村 建司
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  • 22.  鵜飼 英樹
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  • 23.  大出 晃士
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  • 24.  隅山 健太
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  • 25.  洲崎 悦生
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